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Journal articles on the topic 'Basal cell carcinoma'

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Author: Grafiati

Published: 4 June 2021

Last updated: 27 July 2024

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1

Aoki, Natsuko, Hiroyuki Morisaka, Kimiko Nakajima, and Shigetoshi Sano. "Adenoid-cystic Basal Cell Carcinoma." Nishi Nihon Hifuka 78, no. 2 (2016): 99–100. http://dx.doi.org/10.2336/nishinihonhifu.78.99.

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2

Bennani, Mounia, Rhizlane Chaoui, Sara Elloudi, Zakia Douhi, Hanane BayBay, and Fatima Zahra Mernissi. "Axillary basal cell carcinoma: New case report." Journal of Clinical Research and Reports 3, no. 4 (March 13, 2020): 01–03. http://dx.doi.org/10.31579/2690-1919/058.

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Basal cell carcinoma (BCC) is the most common skin cancer, but significant differences exist in its incidence in the various anatomical locations. Unusual sites include the axillae, breasts, perianal area, genitalia, palms, and soles the axilla is one of the most sun-protected body sites and represents a rare location at which BCC develops, up to 2014, 70 cases of axillary BCC were reported in 69 patients (4) then in 2017, 6 new cases were reported in a Japanese study out of a total of 333 CBC, probably the real incidence is underestimated because no systematic study of axillary BCC has generally been conducted.

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3

Kiladze, N., T. Shulaia, A. Bulinska, and L. Abrahamovych. "Dermatoscopic Criteria of Non-Pigmented Basal Cell Carcinoma." Lviv clinical bulletin 3, no. 7 (September 12, 2014): 32–34. http://dx.doi.org/10.25040/lkv2014.03.032.

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4

Gheewala Dinesh Prasad, Frenali. "A Rare Site of Basal Cell Carcinoma - Axilla!" International Journal of Science and Research (IJSR) 12, no. 2 (February 5, 2023): 1349–50. http://dx.doi.org/10.21275/sr23217224739.

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5

Kuijpers, Danielle I., Monique R. Thissen, and Martino H. Neumann. "Basal Cell Carcinoma." American Journal of Clinical Dermatology 3, no. 4 (2002): 247–59. http://dx.doi.org/10.2165/00128071-200203040-00003.

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6

Alexander Paterson, Luke. "Basal cell carcinoma." InnovAiT: Education and inspiration for general practice 14, no. 4 (February 15, 2021): 250–57. http://dx.doi.org/10.1177/1755738021990416.

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Basal cell carcinomas are the most common of all skin cancers, but are often overlooked, perhaps in the wake of increased public awareness of the dangers posed by malignant melanoma. The incidence has been increasing rapidly, adding to the workload of an already stretched primary and secondary care service. A better understanding of how these slow-growing lesions present and behave may help GPs to feel more comfortable managing patients in primary care.

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7

Arenberger, Petr, and Jiří Ettler. "Basal cell carcinoma." Onkologie 10, no. 2 (May 1, 2016): 62–65. http://dx.doi.org/10.36290/xon.2016.015.

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8

Mustofa, Ali, Tri Rosalia Nur Sholikah, Tapi Singgar Niari, and Yuli Wahyu Rahmawati. "Basal Cell Carcinoma." MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan 9, no. 1 (February 1, 2022): 62. http://dx.doi.org/10.26714/magnamed.9.1.2022.62-68.

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Background: Basal Cell Carcinoma (BCC) is a malignant neoplasm of non-keratinized cells in the basal layer of the epidermis, which is locally invasive, aggressive, destructive, and rarely metastasizes. BCC more commonly occurs in the elderly. Exposure to ultraviolet (UV) rays is the main risk factor for BCC, so predilection is areas of the body that are exposed to UV rays, especially the face, ears, and neck.Case presentation: The following is a case report of a 65-year-old female patient who works as a farmer. The patient was diagnosed with basal cell carcinoma (BCC) with complaints of black nodules on the face, itching, and bleeding easily. With Dermatological status obtained. The lesion ad regio Fascialis Dextra shows a solitary hyperpigmented nodule, nummular in size, well-circumscribed, and unilateral.Conclusion:Basal cell carcinoma is a malignant skin tumor originating from non-keratinizing cells in the basal layer of the epidermis.

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9

AFTAB, MUHAMMAD FARRUKH, IRFAN AHMAD, and ABDUL MANAN. "BASAL CELL CARCINOMA." Professional Medical Journal 14, no. 02 (September 6, 2007): 204–11. http://dx.doi.org/10.29309/tpmj/2007.14.02.4876.

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Introduction:- Basal cell carcinoma is the most common skinmalignancy, accounting for about 80% of all skin cancers and may be lethal. Its recognition and management shouldbe familiar to all the general surgeons. Objective:- To describe the prevalence, mode of presentation and varioussurgical options of reconstruction in the management of basal cell carcinoma (BCC) with a local perspective. Setting:-Nishtar Hospital, Multan. Duration:- One year (October 2002 to September 2003). Sample size:- 60 patients. Studydesign:- Descriptive study. Results:- Out of sixty cases, 50 (83%) were male and 10 (17%) were female. Majority ofthe patients presented to us above the age of 45 years and the incidence of BCC increases with the age. The male tofemale ratio was 5:1. Out of 60 cases 26 (20 male, 6 female) 43.3% were farmer, 16 (all male) 26.6% was constructionworkers, 10 (8 male, 2 female) 16.6% were unemployed and 8 (all female) 13.3% were household. No patient presentedbefore 5 years after the development of the lesion. 34 (30 male, 4 female) 56.6% for the last 6-10 years, 20 (16 male,4 female) 33.3% for the last 11-15 years, 2 (all male) 3.3% for 16-20 years and 4 (2 male, 2 female) 6.6% had lesionsfor > 20 years. All the lesions encountered in present study occurred on exposed head and neck region as is evidentfrom the table-III. Most of the patients had the nodular pigmented type of BCC and majority of them were male. Noneof them have Gorlin’s syndrome (Table-IV). Common variant on histopathology was found to be solid type withadenocystic type being the commonest lesion. After the excision of the lesion the skin defect most of the time wasclosed by the mean of split skin graft. Direct closure was done in quarter of the patients. A number of postoperativecomplications were observed after various reconstructive procedures. Wound was found to be commonest complication;with majority of cases getting only minor wound infection. Conclusion:- Delay in presentation has an overall negativeeffect on the outcome. A simple excision, excision biopsy with adequate margin clearance gives surgeon more freedomfor reconstruction.

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10

Rubin, Adam I., Elbert H. Chen, and Désirée Ratner. "Basal-Cell Carcinoma." New England Journal of Medicine 353, no. 21 (November 24, 2005): 2262–69. http://dx.doi.org/10.1056/nejmra044151.

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11

Hacker, Steven M., John F. Browder, and Francisco A. Ramos-Caro. "Basal cell carcinoma." Postgraduate Medicine 93, no. 8 (June 1993): 101–11. http://dx.doi.org/10.1080/00325481.1993.11701719.

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12

Haupt, Helen M., Jere B. Stern, and Mouta S. Dilaimy. "Basal Cell Carcinoma." American Journal of Surgical Pathology 24, no. 9 (September 2000): 1291–94. http://dx.doi.org/10.1097/00000478-200009000-00014.

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13

Brooke, Rebecca CC. "Basal cell carcinoma." Clinical Medicine 5, no. 6 (November 1, 2005): 551–54. http://dx.doi.org/10.7861/clinmedicine.5-6-551.

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14

Lear, J. T., I. Harvey, D. De Berker, R. C. Strange, and A. A. Fryer. "Basal cell carcinoma." Journal of the Royal Society of Medicine 91, no. 11 (November 1998): 585–88. http://dx.doi.org/10.1177/014107689809101110.

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15

Eagle, Kim, Jeffrey S. Dover, and Richard A. Johnson. "Basal-Cell Carcinoma." New England Journal of Medicine 329, no. 8 (August 19, 1993): 545. http://dx.doi.org/10.1056/nejm199308193290806.

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16

Wong, C. S. M. "Basal cell carcinoma." BMJ 327, no. 7418 (October 4, 2003): 794–98. http://dx.doi.org/10.1136/bmj.327.7418.794.

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17

GROSSHANS, E. "Basal cell carcinoma." Journal of the European Academy of Dermatology and Venereology 11 (September 1998): S51—S52. http://dx.doi.org/10.1016/s0926-9959(98)94736-5.

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18

Cannon, Paul S., Shyamala C. Huilgol, Dinesh Selva, and Raman Malhotra. "Basal Cell Carcinoma." Ophthalmology 116, no. 11 (November 2009): 2266–67. http://dx.doi.org/10.1016/j.ophtha.2009.06.034.

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19

Goldberg, L. H. "Basal cell carcinoma." Lancet 347, no. 9002 (March 1996): 663–67. http://dx.doi.org/10.1016/s0140-6736(96)91208-8.

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20

RISHIRAJ, BOB, and JOEL B. EPSTEIN. "BASAL CELL CARCINOMA." Journal of the American Dental Association 130, no. 3 (March 1999): 375–80. http://dx.doi.org/10.14219/jada.archive.1999.0207.

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21

Chung, Seum. "Basal Cell Carcinoma." Archives of Plastic Surgery 39, no. 2 (2012): 166. http://dx.doi.org/10.5999/aps.2012.39.2.166.

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22

POLLACK, SHELDON V. "Basal Cell Carcinoma." Journal of Dermatologic Surgery and Oncology 12, no. 8 (August 1986): 797–804. http://dx.doi.org/10.1111/j.1524-4725.1986.tb01985.x.

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23

Lear, J. T., and A. G. Smith. "Basal cell carcinoma." Postgraduate Medical Journal 73, no. 863 (September 1, 1997): 538–42. http://dx.doi.org/10.1136/pgmj.73.863.538.

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24

&NA;. "Basal cell carcinoma." Advances in Anatomic Pathology 6, no. 6 (November 1999): 335. http://dx.doi.org/10.1097/00125480-199911000-00012.

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25

Matuschek, Christiane, Norman Philipp Hoff, Matthias Peiper, Wilfried Budach, Peter Arne Gerber, and Edwin Bölke. "Basal cell carcinoma." Wiener klinische Wochenschrift 122, no. 7-8 (April 2010): 219. http://dx.doi.org/10.1007/s00508-010-1368-3.

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26

Sobanko, Joseph F., Cassio Lynm, and Misha Rosenbach. "Basal Cell Carcinoma." JAMA Dermatology 149, no. 6 (June 1, 2013): 766. http://dx.doi.org/10.1001/jamadermatol.2013.368.

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27

Ramachandran, Sudarshan, Anthony A. Fryer, Andrew G. Smith, John T. Lear, Bill Bowers, Christopher E. M. Griffiths, Peter W. Jones, and Richard C. Strange. "Basal cell carcinoma." Cancer 89, no. 5 (September 1, 2000): 1012–18. http://dx.doi.org/10.1002/1097-0142(20000901)89:5<1012::aid-cncr10>3.0.co;2-o.

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28

Cameron, Michael C., Erica Lee, Brian P. Hibler, Cerrene N. Giordano, Christopher A. Barker, Shoko Mori, Miguel Cordova, Kishwer S. Nehal, and Anthony M. Rossi. "Basal cell carcinoma." Journal of the American Academy of Dermatology 80, no. 2 (February 2019): 321–39. http://dx.doi.org/10.1016/j.jaad.2018.02.083.

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29

Cameron, Michael C., Erica Lee, Brian P. Hibler, Christopher A. Barker, Shoko Mori, Miguel Cordova, Kishwer S. Nehal, and Anthony M. Rossi. "Basal cell carcinoma." Journal of the American Academy of Dermatology 80, no. 2 (February 2019): 303–17. http://dx.doi.org/10.1016/j.jaad.2018.03.060.

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30

Chuang, Tsu-Yi, Andrei Popescu, W. P. Daniel Su, and Christopher G. Chute. "Basal cell carcinoma." Journal of the American Academy of Dermatology 22, no. 3 (January 1990): 413–17. http://dx.doi.org/10.1016/0190-9622(90)70056-n.

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31

Faqe Qadir, Chnoor Mohammed, and Karzan Ghafur Khidhir. "Investigating Expression of Skin Basal Cell Carcinoma Molecular Biomarkers." Journal of Zankoy Sulaimani - Part A 22, no. 1 (April 5, 2020): 265–72. http://dx.doi.org/10.17656/jzs.10791.

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32

Bensaida, Lamiaa, Sarah Sabur, Samir Mazouz, Noureddine Gharib, and Abdellah Abbassi. "Extensive perianal basal cell carcinoma: a case report." International Journal of Medical Reviews and Case Reports 2, Reports in Surgery and Dermatolo (2019): 1. http://dx.doi.org/10.5455/ijmrcr.extensive-perianal-basal-cell-carcinoma.

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33

Snarskaya, Elena S., L. R. Plieva, and I. S. Maximov. "Metatypical basal cell carcinoma in young man." Russian Journal of Skin and Venereal Diseases 19, no. 3 (June 15, 2016): 132–36. http://dx.doi.org/10.18821/1560-9588-2016-19-3-132-136.

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Malignant epithelial skin tumors are leading among oncological diseases worldwide. In most cases epithelial skin tumors affect areas, susceptible to the action of adverse environmental factors. Metatypical basal cell carcinoma is a variant of basal cell carcinoma that combines the features of basal cell and squamous cell carcinomas. It characterized by infiltrative growth and the destruction of the underlying tissues, pain, bleeding, formation of distant metastases and frequent relapses. Metatypical basal cell carcinoma is more common in women, with the average age is 70.5 years. Historical data, the results of own clinical investigations, rare case of metatypical basal cell carcinoma of the young man, who was successfully treated with recombinant interferon-a2 and prospidinum are presented.

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34

Gómez Sánchez, J., P. de Castro Monedero, and B. Mirón Pozo. "Basal cell carcinoma of perianal location." Cirugía Andaluza 31, no. 2 (May 8, 2020): 193–95. http://dx.doi.org/10.37351/2020312.26.

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Resumen El carcinoma basocelular constituye el cáncer de piel más habitual, representando aproximadamente el 80% de los tumores malignos cutáneos no melanoma. Su origen, en las células basales epidérmicas, parece estar desencadenado por la sobreexposición solar, por eso aparece con frecuencia en la región facial, cervical y tronco. Su aparición en áreas no expuestas al sol, como la región perianal, es extremadamente rara, representando en esta región el 0,2% de todos los carcinomas basocelulares diagnosticados. Se presenta a continuación el caso clínico de un carcinoma basocelular tipo nodular a nivel perianal, con el objetivo de exponer su imagen y tratamiento dada su anecdótica incidencia.

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35

Mehta, Karaninder S., Vikram K. Mahajan, Pushpinder S. Chauhan, Anju Lath Sharma, Vikas Sharma, C. Abhinav, Gayatri Khatri, Neel Prabha, Saurabh Sharma, and Muninder Negi. "Metastatic Basal Cell Carcinoma: A Biological Continuum of Basal Cell Carcinoma?" Case Reports in Dermatological Medicine 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/157187.

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Basal cell carcinoma (BCC) accounts for 80% of all nonmelanoma skin cancers. Its metastasis is extremely rare, ranging between 0.0028 and 0.55 of all BCC cases. The usual metastasis to lymph nodes, lungs, bones, or skin is from the primary tumor situated in the head and neck region in nearly 85% cases. A 69-year-old male developed progressively increasing multiple, fleshy, indurated, and at places pigmented noduloulcerative plaques over back, chest, and left axillary area 4 years after wide surgical excision of a pathologically diagnosed basal cell carcinoma. The recurrence was diagnosed as infiltrative BCC and found metastasizing to skin, soft tissue and muscles, and pretracheal and axillary lymph nodes. Three cycles of chemotherapy comprising intravenouscisplatin (50 mg) and 5-florouracil (5-FU, 750 mg) on 2 consecutive days and repeated at every 21 days were effective. As it remains unclear whether metastatic BCC is itself a separate subset of basal cell carcinoma, we feel that early BCC localized at any site perhaps constitutes a biological continuum that may ultimately manifest with metastasis in some individuals and should be evaluated as such. Long-standing BCC is itself potentially at risk of recurrence/dissemination; it is imperative to diagnose and appropriately treat all BCC lesions at the earliest.

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36

Prathyusha, G., L. Krishna, M. Jyothi, and Y. Sravanthi. "Pigmented Basal Cell Carcinoma – Adenoid Cystic Pattern: A Rare Case Report." Scholars Journal of Medical Case Reports 10, no. 12 (December 20, 2022): 1225–28. http://dx.doi.org/10.36347/sjmcr.2022.v10i12.020.

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Basal cell carcinoma is the most common malignant tumour of skin, comprising 80% of non-melanoma cancers. Intermittent exposure to ultraviolet radiation is an important risk factor. Pigmented basal cell carcinoma is a clinical and histological variant of basal cell carcinoma that exhibits increased pigmentation. It is a very rare variant, although its frequency can reach upto 6% of total basal cell carcinomas. Herein, we are reporting a case of pigmented basal cell carcinoma of nose which is a rare presentation.

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37

Nasser, Nilton, Nilton Nasser Filho, Bruno Trauczynski Neto, and Lissandra Melati da Silva. "Giant basal cell carcinoma." Anais Brasileiros de Dermatologia 87, no. 3 (June 2012): 469–71. http://dx.doi.org/10.1590/s0365-05962012000300019.

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The basal cell carcinoma is the most common skin cancer but the giant vegetating basal cell carcinoma reaches less than 0.5 % of all basal cell carcinoma types. The Giant BCC, defined as a lesion with more than 5 cm at its largest diameter, is a rare form of BCC and commonly occurs on the trunk. This patient, male, 42 years old presents a Giant Basal Cell Carcinoma which reaches 180 cm2 on the right shoulder and was negligent in looking for treatment. Surgical treatment was performed and no signs of dissemination or local recurrence have been detected after follow up of five years.

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38

Rosen, Jordan, Katherine Nolan, Noah Shaikh, Les Rosen, and Martin Zaiac. "Coexisting Basal Cell Carcinoma and Squamous Cell Carcinoma in Congenital Nevus Sebaceous." SKIN The Journal of Cutaneous Medicine 2, no. 3 (April 30, 2018): 181–85. http://dx.doi.org/10.25251/skin.2.3.6.

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Nevus sebaceous is a congenital epidermal hamartoma characterized by hyperplastic changes to the epidermis and adnexa. Nevus sebaceous is associated with an elevated risk of cutaneous neoplasms, most often benign; however, malignant neoplasms, most notably basal cell carcinoma, can also present in these patients. Although a rare occurrence, more often affecting adult patients, squamous cell carcinomas have also been reported to arise at the site of pre-existing nevus sebaceous. Herein we report a unique case of a patient with basal cell carcinoma and squamous cell carcinoma arising concurrently in the same nevus sebaceous.

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39

Proia, Alan D., M. Angelica Selim, Jason C. Reutter, and John J. Michon. "Basal Cell–Signet-Ring Squamous Cell Carcinoma of the Eyelid." Archives of Pathology & Laboratory Medicine 130, no. 3 (March 1, 2006): 393–96. http://dx.doi.org/10.5858/2006-130-393-bcscco.

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Abstract A 93-year-old woman developed a mass on her right lower eyelid that was present for more than 6 months but underwent rapid expansion during several weeks prior to her ophthalmological evaluation. Examination revealed an approximately 1.8 cm in diameter, fleshy, fungating growth involving more than 60% of the right lower eyelid. Excisional biopsy disclosed a neoplasm arising from the epidermis composed of adjoining basal cell and signet-ring squamous cell carcinoma, without a transition zone. The cells comprising the basal and squamous cell carcinomas were distinct immunophenotypically, with only the basal cell carcinoma reacting with Ber-EP4 and CAM 5.2 antibodies. To our knowledge, this case represents the first example of a collision tumor composed of basal cell and signet-ring squamous cell carcinoma.

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40

Sarma, Deba P., Daniel Olson, Jennifer Olivella, Tracey Harbert, Bo Wang, and Stephanie Ortman. "Clear Cell Basal Cell Carcinoma." Pathology Research International 2011 (April 20, 2011): 1–4. http://dx.doi.org/10.4061/2011/386921.

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Introduction. Clear cell basal cell carcinoma (BCC) is an uncommon and unusual variant of BCC, which is characterized by a variable component of clear cells. The pathogenesis of this histological variant and its clinical significance has not been clarified. Differentiation of this uncommon variant of BCC from other clear cell tumors is important for the treatment. Case Presentation. A 65-year-old male presented with a 0.9 cm dome-shaped lesion on his upper chest. A shave biopsy revealed a dermal basaloid tumor that comprised nests with a peripheral palisading pattern, retraction artifacts, and striking clear cell changes. Histopathologic examination, along with findings from immunohistochemical studies and special staining of the clear cells, supports the diagnosis of clear cell basal cell carcinoma. Conclusion. Clear cell BCC is a rare and unusual variant of BCC. The underlying pathogenesis of this subtype is unclear; however, accurate identification may affect treatment and prognosis.

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41

Claassen, Stephanie L., Michael C. Royer, and Walter L. Rush. "Granular Cell Basal Cell Carcinoma." American Journal of Dermatopathology 36, no. 7 (July 2014): e121-e124. http://dx.doi.org/10.1097/dad.0000000000000020.

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42

Dundr, Pavel, Jiri Stork, Ctibor Povysil, and Frantisek Vosmik. "Granular cell basal cell carcinoma." Australasian Journal of Dermatology 45, no. 1 (February 2004): 70–72. http://dx.doi.org/10.1111/j.1440-0960.2004.00034.x.

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43

Mrak, R. E., and G. F. Baker. "Granular cell basal cell carcinoma." Journal of Cutaneous Pathology 14, no. 1 (February 1987): 37–42. http://dx.doi.org/10.1111/j.1600-0560.1987.tb00124.x.

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44

STARINK, T. M., C. E. M. BLOMJOUS, T. J. STOOF, and J. C. VAN DER LINDEN. "Clear cell basal cell carcinoma." Histopathology 17, no. 5 (November 1990): 401–5. http://dx.doi.org/10.1111/j.1365-2559.1990.tb00759.x.

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45

Roewe, R. J., Matthew A. Uhlman, Nathan A. Bockholt, and Amit Gupta. "Basal Cell Carcinoma of the Penis: A Case Report and Review of the Literature." Case Reports in Urology 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/173076.

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Basal cell carcinoma of the penis is an extremely rare entity, accounting for less than 0.03% of all basal cell carcinomas. Fortunately, wide local excision of such lesions is generally curative. Fewer than 25 cases have been reported in the literature describing penile basal cell carcinoma. Here we report a case of penile basal cell carcinoma cured with wide local excision.

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46

Carroll, David M., Elizabeth M. Billingsley, and Klaus F. Helm. "Diagnosing Basal Cell Carcinoma by Dermatoscopy." Journal of Cutaneous Medicine and Surgery 3, no. 2 (October 1998): 62–67. http://dx.doi.org/10.1177/120347549800300202.

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Background: Dermatoscopy (DS) has been used primarily to evaluate pigmented skin lesions. Little information is available on DS findings of basal cell carcinoma (BCC). Dermatoscopy is a noninvasive technique that allows visualization of cutaneous features from the skin surface to the papillary dermis. Basal cell carcinoma, the most common cutaneous malignancy, is traditionally diagnosed clinically and confirmed with biopsy. Objective: To determine the dermatoscopic features of non-pigmented basal cell carcinomas. Methods: The dermatoscopic findings of 27 lesions that clinically were suspicious for BCC were analyzed. Results: Of these 27 clinically suspect lesions, the biopsies revealed BCC in 20 specimens and squamous cell carcinoma (SCC) in two specimens. Twenty of these 22 specimens had dermatoscopic findings of BCC: diffusely distributed, branching blood vessels, asymmetric, and narrow blood vessels distributed deeper in the dermis, or a milky-red corona with superficial wide blood vessels. One nodular BCC in our study showed no distinct findings. Conclusions: Many BCCs have characteristic DS findings; however, dermatoscopic examination of some tumours will not demonstrate any known characteristic findings. As such, the DS criteria we propose for BCC are best utilized as an adjunctive study of clinical impressions. Biopsy remains the definitive diagnostic tool.

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47

Kadam, Sameer Arun, Kirti G. Pardeshi, Hoogar Mallinath Basalingappa, Satish Bhasale, Vaishali Bhonsle, Nakul Sampat, and Arvind Valand. "Multiple-lesion, non-familial basal cell carcinoma-An interesting oddity." IP Journal of Diagnostic Pathology and Oncology 8, no. 4 (December 15, 2023): 225–29. http://dx.doi.org/10.18231/j.jdpo.2023.053.

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Basal cell carcinoma (BCC) is the most common primary carcinoma of skin, which accounts for three-fourth of all primary skin tumours. Basal carcinoma occurs commonly as a single lesion, though occasionally it can occur as Multiple lesions, which may occur in close association with heredofamilial conditions such as nevoid basal cell carcinoma syndrome (Gorlin’s syndrome), Bazex syndrome, Rombo syndrome, and unilateral basal cell nevus syndrome. The case of multiple basal cell carcinomas being presented here is unique in its occurrence inasmuch as it is not associated with heredofamilial conditions, and despite not being associated with heredofamilial conditions there is occurrence of multiple basal carcinomas in a patient in a tertiary care hospital in a dominantly tribal region. The patient has no family history of genodermatosis that could increase the incidence of multiple basal cell carcinomas such as xeroderma pigmentosum, and no history of other predisposing conditions including actinic keratosis, Bowen’s Disease, leukoplakia, Erythroplasia of Queyrat, keratoacanthoma, radiation dermatitis and exposure to arsenicals, psoralen and other photosensitizing medications. However, the patient had history of having raised macules over the face which were diagnosed as seborrheic keratosis.

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48

Lu, Qingli, Yuanyuan Qu, Yuan Ding, and Xiaojing Kang. "p75NTR/proBDNF Modulates Basal Cell Carcinoma (BCC) Immune Microenvironment via Necroptosis Signaling Pathway." Journal of Immunology Research 2021 (February 1, 2021): 1–10. http://dx.doi.org/10.1155/2021/6652846.

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Basal cell carcinoma (BCC) is the most common skin cancer. While most of the basal cell carcinomas were localized lesion and can be easily managed, the treatment options to the advanced basal cell carcinomas are still remarkably limited. In recent years, proBDNF and its receptor p75NTR have been reported to play important roles in various diseases, including cancers and psychotic disorders. However, the role of p75NTR/proBDNF signaling in basal cell carcinoma remains unclear. Here, we found that the expression level of p75NTR/proBDNF was decreased in basal cell carcinoma patient samples and cell lines. In vitro study showed overexpression of p75NTR/proBDNF could significantly facilitate tumor cell death, including inflammatory-silent apoptosis and lytic inflammatory activated necroptosis. In vivo study showed overexpression of p75NTR/proBDNF dramatically promotes tumor-associated macrophage (M1) and T cell recruitment in a syngeneic mouse model of BCC. These results show a crucial role for p75NTR/proBDNF signaling in basal cell carcinoma immune microenvironment.

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Damin, Daniel C., Mario A. Rosito, Pedro Gus, Claudio Tarta, Marcos Weindorfer, Marcos B. Burger, and Andre Cartell. "Perianal Basal Cell Carcinoma." Journal of Cutaneous Medicine and Surgery 6, no. 1 (January 2002): 26–28. http://dx.doi.org/10.1177/120347540200600106.

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Abstract:

Background: A case of basal cell carcinoma (BCC) of the perianal region is reported. This tumor is extremely rare in this location and behaves rather innocently. Objective: Clinical and histopathologic characteristics of perianal BCC, as well as the choices of treatment, are outlined. Conclusion: The tumor should be histologically distinguished from basaloid carcinoma of the anus, which is much more aggressive and metastasizes early, thus requiring a different therapy.

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Shah, Isha, Aastha Shah, and U. Suryanarayan. "Metastatic basal cell carcinoma." Journal of Radiation and Cancer Research 12, no. 1 (2021): 27. http://dx.doi.org/10.4103/jrcr.jrcr_24_20.

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