Dissertations / Theses on the topic 'B pr'
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Oliveira, Mara Cristina Lopes de. "Preparação de ímas HDDR e ligas de Pr-Fe-Co-B-Nb-M (M=Al, P, Cu, Ga e/ou Gd) e caracterização de suas propriedades magnéticas e resistência à corrosão." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/85/85134/tde-21092009-103331/.
Full textHDDR process has attracted great interest for producing polymer- bonded rareearth based magnets. It presents commercial advantages when compared with conventional sintered magnets owing to easy and low cost manufacturing. With the development of anisotropic powders using praseodymium, the expectations about this process grow e also the need for studying new compositions and alloy additions. In this work the magnetic properties of polymer-bonded magnets prepared with PrFeB magnetic alloys using HDDR process have been studied. Pr14FebalCo16B6Nb0,1 was used as the reference alloy Phosphorus, copper, aluminium, galium and gadolynium additions have been performed to increase the magnetic properties of the reference alloy. The microstructural characterization of the magnets has been carried out through optical microscopy and SEM. The complex microsctructure influences the electrochemical behavior of the magnetic alloys. The literature about this subject is scarce. Thus, the corrosion resistance of the different alloys prepared during this work was evaluated using electrochemical impedance spectroscopy and potentiodynamic polarization curves. A correlation between the microstructural features and the electrochemical behavior of the alloys has been established. The results showed that phosphorus and aluminium additions up to 1.0wt% had a beneficial effect on the magnetic properties and corrosion resistance of the alloys. Copper additions, on the other hand, strongly diminished the magnetic properties of the reference alloy.
Bollero, Real Alberto. "Isotropic nanocrystalline (Nd,Pr)(Fe,Co)B permanent magnets." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2003. http://nbn-resolving.de/urn:nbn:de:swb:14-1069758225796-19366.
Full textNanocrystalline permanent magnets present unusual magnetic properties because of surface/interface effects different from those of bulk or microcrystalline materials. This work presents results of a systematic investigation of the relationship between microstructure and magnetic properties in isotropic nanocrystalline (Nd,Pr)(Fe,Co)B permanent magnets. Highly coercive (Nd,Pr)FeB-type magnets have been produced using high energy ball milling and melt-spinning. The influence of small amounts of additives, Dy and Zr, and the substitution of Nd by Pr on the microstructural and magnetic properties are shown. An assessment of the hot deformation behaviour has been carried out. Intensive milling of an alloy with starting composition Pr9Nd3Dy1Fe72Co8B6.9Zr0.1 yields, after annealing treatment, nearly single-phase magnet powders with a maximum energy product (BH)max?î140kJm-3. Co has a beneficial effect on the intrinsic magnetic properties but also on the microstructure, with a mean grain size of 20nm. Intensive milling is used to produce high-performance nanocomposite magnets by blending this latter alloy with different fractions of soft magnetic alfa-Fe. Addition of 25wt.% alfa-Fe leads to a high (BH)max=178 kJm-3 due to an effective exchange-coupling between the hard and the soft magnetic phases. The intergrain interactions between the crystallites of the nanocomposite structure are analysed. Demagnetisation recoil loops of the nanocomposite magnets show relatively open minor loops due to the exchange-spring mechanism. Information about the intergrain interactions during demagnetisation are obtained by plotting the deviation of the demagnetising remanence from the Wohlfarth-model (¡§deltaJ-plot¡¨). Exchange-coupling phenomena are studied by analysing the evolution of the corresponding deltaJ values when varying (i) the alfa-Fe content, (ii) the annealing temperature, i.e. the grain size and (iii) the measurement temperature. Low temperature measurements do not reveal any sign of spin reorientation for these Pr-based nanocomposite magnets. The work concludes showing the possibility of using a mechanically activated gas-solid reaction to obtain an effective grain refined microstructure starting from stoichiometric Nd2(Fe1-xCox)14B alloys (x=0-1). These compounds were milled under enhanced hydrogen pressure and temperature leading to their disproportionation into NdH2+delta and bcc-(Fe,Co) (x=0-0.75) or fcc-Co (x=1). Grain sizes of recombined Nd2(Fe,Co)14B materials were found to be 40-50nm
Shabani, Naim. "Prognostische Signifikanz der Expression von Estrogenrezeptor alpha (ER-α) und beta (ER-β), Progesteronrezeptor A (PR-A) und B (PR-B) in Endometriumkarzinomen." Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-79711.
Full textCorfield, Martin Richard. "Production of sintered permanent magnets based on (Nd/Pr)Fe-B alloys." Thesis, University of Birmingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410302.
Full textJúnior, Carlos Valério da Rocha. "Padrão de metilação do receptor de progesterona (PGR) em endométrio eutópico de pacientes com infertilidade relacionada à endometriose durante a fase secretora." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/17/17145/tde-20072016-100229/.
Full textEndometriosis is a disease characterized by ectopic growth of endometrial tissue histologically similar to the eutopic endometrium. Among this symptoms, is infertility accounts which is related to decreased endometrial receptivity and resistance to progesterone, important hormone involved in the establishment of this process and the maintenance of pregnancy. The etiology of endometriosis is not well known, but studies suggest that this disorder can be linked to epigenetic mechanisms of regulation of gene expression such as DNA methylation. The endometrial responsiveness to progesterone is mediated by receptors (PR-A and PR-B) which seem to be suppressed in these patients, possibly reducing or inactivity of these receptors, which could be a mechanism involved in the infertility associated with endometriosis. Studies in methylation of the gene encoding the A and B isoforms of progesterone receptor (PGR) showed that exon 1 of the PR-B isoform is hypermethylated and silenced have its expression in patients with the disease. However it has not been rated the methylation profile of this gene in infertile women with the disease, which could be involved in the infertility presented by these patients. The goal from study was to evaluate the methylation pattern of the PGR gene in eutopic endometrium of women with infertility related to endometriosis and infertile controls during the secretory phase. Endometrial biopsies were performed on 12 23 patients, divided into two groups: 12 infertile women without endometriosis (infertile Control) and 11 infertile women with endometriosis (Endometriosis). All endometrium collected were confirmed in the secretory phase of the cycle by classical histological analysis according to the criteria of Noyes. Genomic DNA was extracted with the QIAamp DNA Mini Kit and using the modified EpiTec Bissulfite Kit. The methylation pattern of PR-A and PR-B isoforms was assessed by HRM technique (Melting High Resolution) Methylation analysis of PR isoform The analyzed showed that the region is hipometilada, wherein the percentage of methylation was found 0% in both the groups with and without endometriosis. However, in the group with endometriosis, the PR-B isoform showed partially methylated in most patients with methylation percentage of 50% (n = 8), only one patient showed methylation in 80% of isoform B. In the group without endometriosis the PR-B isoform was shown hipometilada (0%). The hypomethylation of PR-A isoform suggests that this gene be in its active form, without change in his expression. However, hypermethylation of the PR-B isoform in women with endometriosis may be associated with gene silencing or reducing the expression, suggesting that the low response to progesterone in women with endometriosis can be directly linked to the reduction of its receptors in these patients
Suarez, Guillermo Mendoza. "Magnetic properties of nanostructure and hot-deformed melt-spun Pr-Fe-B alloys." Thesis, University of Sheffield, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264436.
Full textFARIA, JUNIOR RUBENS N. de. "The Structures and properties of Pr/Nd-Fe-B-(Cu) permanent magnets and alloys." reponame:Repositório Institucional do IPEN, 1993. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10359.
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Thesis (Ph.D)
IPEN/T
University of Birmingham, Birmingham, England
Siqueira, Scheyla Daniela Vieira da Silva. "Anfotericina b pr?-aquecida: um novo sistema terap?utico para infec??es f?ngicas." Universidade Federal do Rio Grande do Norte, 2013. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13404.
Full textCoordena??o de Aperfei?oamento de Pessoal de N?vel Superior
2020-01-01
O aquecimento moderado (70?C por 20 min) de solu??es micelares de Anfotericina B (AmB) gera um rearranjo molecular que apresenta diminui??o significativa na sua toxicidade sem comprometer sua atividade. O objetivo desse trabalho foi avaliar aspectos f?sico-qu?micos e farmacol?gicos das solu??es micelares de Anfotericina B n?o-aquecida (AmB-M) e aquecida (AmB-A) antes e ap?s o congelamento e posterior liofiliza??o. Para isso foram feitas avalia??es antes e depois do congelamento e secagem. As amostras foram analisadas nas seguintes concentra??es: 50 mg.L-1, 5 mg.L-1, 0,5 mg.L-1 e 0,05 mg.L-1. O teste de libera??o de pot?ssio e hemoglobina de eritr?citos foi realizado para avaliar a toxicidade aguda e cr?nica, respectivamente. A efic?cia das solu??es foi analisada por meio da libera??o de pot?ssio e do teste da concentra??o inibit?ria m?nima em uma cepa de Candida albicans. Ap?s o aquecimento, foi observada uma turva??o caracter?stica do rearranjo estrutural molecular da AmB aquecida. Adicionalmente, a AmB-A apresentou deslocamento no comprimento m?ximo de absor??o de 327 nm para 323 nm. Essas caracter?sticas se mantiveram ap?s a liofiliza??o, evidenciando estabilidade f?sico-qu?mica dessa nova forma estrutural micelar. Com rela??o ? toxicidade, a AmB-M produziu significativamente maior valor de libera??o de hemoglobina que a forma aquecida. Esses resultados foram observados independentes do tipo de amostra (antes e depois da liofiliza??o). Por?m, n?o houve diferen?a entre AmB-M e AmB-A quanto ? atividade antif?ngica. Portanto, foi demonstrado que a liofiliza??o n?o mudou o comportamento da forma aquecida da AmB comprovando sua viabilidade para ser liofilizada e produzida em escala industrial
Hardy, Stephen Paul. "Place and its relations in late twentieth century cultural theory and British fiction." Thesis, University of Warwick, 2001. http://wrap.warwick.ac.uk/4171/.
Full textMitchell, Michael. "Hidden mutualities : Faustian themes in the postcolonial." Thesis, University of Warwick, 2000. http://wrap.warwick.ac.uk/4522/.
Full textCrespo-Perona, Miguel Ángel. "An aesthetics of sacredness : a Nietzschean reading of James Joyce and T. S. Eliot." Thesis, University of Warwick, 1999. http://wrap.warwick.ac.uk/4289/.
Full textLangdon, John Douglass. "Rejecting the pale companion : mythemes of immortality in and beyond William Shakespeare's A Midsummer Night's Dream." Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7149/.
Full textMilligan, Tony. "Iris Murdoch's romantic Platonism." Thesis, University of Glasgow, 2005. http://theses.gla.ac.uk/7485/.
Full textAltorf, Marije. "Iris Murdoch and the art of imagination : imaginative philosophy as response to secularism." Thesis, University of Glasgow, 2004. http://theses.gla.ac.uk/1677/.
Full textJohnstone, Michael. "Liberty or death : a practical and theoretical exploration of alternatives to free will and determinism in contemporary historical fiction." Thesis, University of Gloucestershire, 2011. http://eprints.glos.ac.uk/2009/.
Full textVerdum, Priscila de Lima. "Forma??o continuada de professores da educa??o b?sica : pol?ticas e pr?ticas." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2010. http://tede2.pucrs.br/tede2/handle/tede/3645.
Full textEsse estudo insere-se na linha de Forma??o, Pol?ticas e Pr?ticas em Educa??o do PPGEdu da PUCRS e faz parte do conjunto de trabalhos/pesquisas produzidos no CEES (Centro de Estudos em Educa??o Superior /PUCRS). A presente pesquisa teve como tema a forma??o continuada de professores da educa??o b?sica, realizada em parceria entre MEC, Institui??es de Ensino Superior (IES) e Sistemas P?blicos de Ensino (SPE). O objetivo principal foi analisar como um Centro de Pesquisa e Desenvolvimento da Educa??o, selecionado pelo edital SEIF/MEC n? 01/2003, para implementa??o da Rede Nacional de Forma??o Continuada de Professores da Educa??o B?sica (REDE), percebeu essa proposta e atuou no processo de forma??o continuada de professores da educa??o b?sica, a partir da fala dos seus executores e da proposta pedag?gica. Com essa an?lise objetivou-se destacar aspectos importantes de serem considerados numa iniciativa, como essa da REDE, que venham a contribuir para o desenvolvimento profissional docente e, por consequ?ncia, para a melhoria da pr?tica pedag?gica. Trata-se de uma pesquisa de cunho qualitativo, inserida no paradigma construtivista, cuja abordagem utilizada para investiga??o foi o Estudo de Caso, realizado no CAEF - Centro de Artes e Educa??o F?sica, sediado na UFRGS (Universidade Federal do Rio Grande do Sul). Al?m de envolver a pesquisa bibliogr?fica sobre o tema em estudo, a coleta do material para a realiza??o do trabalho teve como fontes: an?lise documental, observa??o direta e entrevistas. Os dados coletados foram examinados a partir da metodologia da An?lise Textual Discursiva (MORAES & GALLIAZI, 2007). O aporte te?rico tem base em autores como: Contreras (2002), Marcelo (1999), P?rez G?mez (1998), Tardif (2002), Perrenoud (2002), N?voa (1995), Candau (1998), Rios (2003), entre outros. O estudo permitiu destacar alguns importantes aspectos de serem considerados numa proposta, como a da REDE, entre eles: a considera??o das necessidades dos professores na planifica??o das a??es; a avalia??o sistematizada da elabora??o, execu??o e resultados das a??es; a profissionaliza??o dos formadores.
Silva, Filho Miguel Adelino da. "An?lise in vitro da atividade antif?ngica e de toxicidade da anfotericina B pr?-aquecida." Universidade Federal do Rio Grande do Norte, 2011. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13349.
Full textThe aim of this work was to evaluate how an aqueous micellar system containing Amphotericin B (AmB) and sodium deoxycholate (DOC) can be rebuilt after heating treatment. Also a review of the literature about the new physicochemical and biological properties of this new system was carried out. Afterwards, heated (AmB-DOC-H) and unheated (AmB-DOC) micelles were subsequently diluted at four different concentrations (50mg.L-1, 5mg.L-1, 0.5mg.L-1 and 0.05mg.L-1) to perform the physicochemical study and, then, the pharmacotoxicity assay, in which two cell models were used for the in vitro experiments, Red Blood Cells (RBC) from human donors and Candida parapisilosis (Cp). While potassium (K+) and hemoglobin leakage from RBC were the used parameters to evaluate the acute and chronic toxicity, respectively, the efficacy of AmB-DOC and AmB-DOC-H were assessed by K+ leakage and cell survival rate from Cp. The spectral study revealed a slight change on the aggregate peak from 327nm to 323nm for AmB-DOC-H compared to AmB-DOC. Concerning the toxicity, although AmB-DOC and AmB-DOC-H presented different behavior for hemoglobin leakage, AmB-DOC produced higher leakage than AmB-DOC-H at high concentrations (from 5mg.L-1) with values tending to zero. However, concerning K+ leakage, both AmB-DOC and AmB-DOC-H, showed similar profile for both cell models, RBC and Cp (p<0,05). AmB-DOC-H and AmB-DOC also revealed similar profile of activity against Cp with equivalent survival rate. In short, the AmB-DOC-H showed much less toxicity than AmB-DOC, but remained as active as the late one against fungal cell. Therefore, the results highlight the importance of this new procedure as a simple, inexpensive and safe alternative to produce a new kind of micelle system for treatment of systemic fungal infections
A anfotericina B micelar (AmB) ? um importante agente antimicrobiano utilizado contra infec??es f?ngicas sist?micas. No entanto, seu uso ? limitado devido a sua alta toxicidade. Formula??es de anfotericina B em estruturas lip?dicas s?o menos t?xicas, por?m apresentam elevado custo. A AmB em solu??o aquosa possui formas monom?ricas e agregadas, estes ?ltimos s?o os respons?veis pelas rea??es adversas. Este trabalho avaliou a AmB desoxicolato de s?dio (AmB-DOC) e AmB aquecida (AmBDOC- H) em rela??o a sua toxicidade e atividade, bem como perfil de seu espectro em quatro concentra??es diferentes (50mg.L-1, 5mg.L-1, 0,5mg.L-1 e 0.05mg.L-1). O aquecimento controlado das solu??es AmB levou a altera??es no espectro de 327nm AmB (agregados) para 323nm (superagregados). Al?m disso, quando as amostras foram submetidas ao processo de dilui??o, apresentam o mesmo comportamento espectrofotom?trico: ambas as amostras diminuem o pico das formas auto-associadas at? apresentarem apenas mon?meros com pico em 409nm, o que sugere um processo de libera??o de mon?meros por concentra??o-dependente. No que diz respeito ? toxicidade, AmB-DOC e AmB-DOC-H apresentaram comportamentos distintos: a taxa de libera??o de hemoglobina de hem?cias para AmB-DOC, em altas concentra??es, foi muito superior a AmB-DOC-H, cujos valores tendem a zero (p <0,05). J? em rela??o ? libera??o de K+ ambas as amostras apresentaram perfil semelhante. Sobre a atividade, AmB-H mant?m o mesmo perfil da AmB-DOC. Em suma, a AmB-DOC-H ? muito menos t?xica do que AmB-DOC e mantendo a atividade. Sendo este procedimento uma alternativa simples, de baixo custo e segura para, em um o futuro pr?ximo, ser utilizada no tratamento de infec??es f?ngicas sist?micas
Santos, Patricia Brissi. "Efeitos da adição de surfactante e moagem de alta velocidade em pós magnéticos à base de Pr-Fe-B obtidos via HDDR." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/85/85134/tde-26012012-145626/.
Full textThis work verified the effect caused by adding the surfactant in the high speed/energy milling in order to obtain Pr12Fe65.9Co16B6Nb0.1 magnetic nanopowders. The first part of this work involved the magnetic powder obtainment through the process of hydrogenation, disproportionation, desorption and recombination (HDDR). The pressure of H2 during the hydrogenation and disproportion steps was 930 mbar and the temperature of desorption and recombination was 840 ºC. Initially, the HDDR powders were subjected a highspeed milling process at 900 rpm, with quantity variations of the milling medium (cyclohexane) and without the addition of oleic acid. Then, the HDDR powders were subjected to the milling process with the addition of oleic acid and with milling time variations. After the milling process, heat treatments of the powder were carried out at 700 °C or 800 °C for 30 minutes in order to obtain the crystallization of the powder. By performing the procedures, it was verified that the milling efficiency improved with the addition of 6.6 ml of cyclohexane as the milling medium and with the addition of oleic acid. It was determined that for the surfactant additions of 0.02 ml to 0.05 ml, with a milling time of up to 360 minutes, powder agglomeration does not occur in the milling pot and the milling efficiency is higher than 90%. The second stage of this work involved the magnetic powders characterization obtained by using vibrating sample magnetometer, scanning electron microscopy, transmission electron microscopy and X-ray diffraction. Through the characterizations it was found that the powders magnetic properties improved when the addition of oleic acid in a high-speed /energy milling occurred. It was also verified that the α-Fe phase, present in the powder, shows a crystallite size decrease (from 35 nm to ~ 10 nm) when the time milling variation occurred; meanwhile, the crystallinity degree was lower in the Pr2Fe14B phase when the time milling variations was carried out.
Liu, Zhongwu. "The sub-ambient, ambient and elevated temperature magnetic properties of nanophase Nd/Pr-Fe-B based alloys." Thesis, University of Sheffield, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419650.
Full textAlves, Selda Gomes de Souza. "Pr?tica do acolhimento ? pessoa idosa na aten??o b?sica: uma estrat?gia de humaniza??o." Universidade Federal do Rio Grande do Norte, 2009. http://repositorio.ufrn.br:8080/jspui/handle/123456789/14689.
Full textThe aging of the population already is a fact, before considered a phenomenon, today, is part of the reality of the majority of the societies in the world. The present study it has as objective to analyze the practical one of the shelter developed for the team to multidiscipline for the elderly in the Strategy of Health of the Family. One is about a descriptive and explorat?ria inquiry, developed by means of quantitative boarding. The population of this study consisted of nineteen teams that work in the inserted ESF in the urban zone of the city of Sousa-PB, understanding a complete of 133 professionals. The collection of date was carried through through a questionnaire contends closed questions, referring to the partner-demographic date e, specific open questions. The main results indicate that the professionals of Health of the city of Sousa, PB, that had participated of this study had consisted in a complete of 76. Amongst these, 20% are nurses, followed of the odont?logos in 6%; 35% are ACS and technician of nursing with 19%. The age of the interviewed ones meets in the age band enters, 21 and 30 years, in 43%. The majority is of the feminine sex with a 84% total. Already in accordance with civil state 34% is married. If treating to the wage, the doctor has of greater of 12 wages. The participants present the percentile greater of formed time of with referring 33% of 1 the 3 years of formation. E finally, the changeable time of performance, if had detached 39% of the participants with 08 the 11 years. With regard to as if it processes the reception and attendance to the person in the ESF, we can observe that, with priority attendance was prominence with 27% of the participants, followed of a considerate attendance with 26%. Already in relation to the actions that are developed daily in the ESF, these they are come back toward the HIPERDIA with 40%, followed of actions ruled in orientation with 27%. Some actions they are carried through in accordance with the aged necessity of each (13%) and through visits domiciliary (9%). It was asked to them as the shelter was facilitated in the UBS, these had told that it is through the attention that is excused the aged one (35%), and finally, as this made it difficult age, in its majority with 37% they had not wanted to answer, followed of the lack of understanding with 26%. With this study it was possible to conclude that the practical one developed for the professionals of the ESF of the city of Sousa, PB with the elderly, is characterized by an assistance ruled in the clinical aspect, little focused in the actions that to permeate the PNH
O envelhecimento da popula??o j? ? um fato, antes considerado um fen?meno, hoje, faz parte da realidade da maioria das sociedades no mundo. O presente estudo tem como objetivo analisar a pr?tica do acolhimento desenvolvida pela equipe multidisciplinar para a pessoa idosa na Estrat?gia de Sa?de da Fam?lia. Trata-se de uma investiga??o descritiva e explorat?ria, desenvolvida mediante abordagem quantitativa. A popula??o deste estudo constituiu-se de dezenove equipes que trabalham na ESF inseridas na zona urbana do munic?pio de Sousa-PB, compreendendo um total de 133 profissionais. A coleta de dados foi realizada atrav?s de um question?rio contendo quest?es fechadas, referente aos dados s?cio-demogr?ficos e, quest?es abertas espec?ficas. Os principais resultados indicam que os profissionais de Sa?de do munic?pio de Sousa, PB, que participaram deste estudo constitu?ram-se num total de 76. Dentre estes, 20% s?o enfermeiros, seguido dos odont?logos em 6%; 35% s?o ACS e t?cnicos de enfermagem com 19%. A idade dos entrevistados encontra-se na faixa et?ria entre, 21 e 30 anos, em 43%. A maioria ? do sexo feminino com um total de 84%. J? de acordo com o estado civil 34% s?o casados. Se tratando do sal?rio, o m?dico tem o de maior de 12 sal?rios. Os participantes apresentam o maior percentual de tempo de formado com 33% referente de 1 a 3 anos de forma??o. E por fim, a vari?vel tempo de atua??o, se destacaram 39% dos participantes com 08 a 11 anos. Com rela??o a como se processa a recep??o e atendimento ? pessoa na ESF, podemos observar que, o atendimento priorit?rio foi destaque com 27% dos participantes, seguido de um atendimento atencioso com 26%. J? em rela??o ?s a??es que s?o desenvolvidas diariamente na ESF, essas est?o voltadas para o HIPERDIA com 40%, seguidas de a??es pautadas em orienta??es com 27%. algumas a??es s?o realizadas de acordo com a necessidade de cada idoso (13%) e atrav?s de visitas domiciliares (9%). Foi-lhes perguntado como o acolhimento era facilitado na UBS, esses relataram que ? atrav?s da aten??o que ? dispensada ao idoso (35%), e por fim, como este era dificultado, em sua maioria com 37% n?o quiseram responder, seguidos da falta de compreens?o com 26%. Com este estudo foi poss?vel concluir que a pr?tica desenvolvida pelos profissionais da ESF do munic?pio de Sousa, PB com a pessoa idosa, ? caracterizada por uma assist?ncia pautada no aspecto cl?nico, pouco focalizado nas a??es que permeiam a PNH
Cossi, Marcelly Santos. "A sa?de do trabalhador na aten??o b?sica: concep??es e pr?ticas dos enfermeiros." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br/handle/123456789/19614.
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O estudo tem por objetivo analisar as concep??es e as pr?ticas desenvolvidas pelos enfermeiros no ?mbito da sa?de do trabalhador na Aten??o B?sica, e justifica-se pela necessidade de amplia??o do conhecimento dessa ?rea tem?tica. Estudo anal?tico com abordagem qualitativa realizado nas unidades de sa?de da aten??o b?sica dos distritos sanit?rios da cidade de Natal-RN, em apenas uma unidade de sa?de de cada bairro. A coleta das informa??es aconteceu entre agosto e outubro de 2014, por meio de entrevistas semiestruturadas, na seguinte sequ?ncia: sele??o dos entrevistados e marca??o da entrevista; realiza??o das entrevistas e aplica??o do instrumento de coletas de dados, a fim de tra?ar o perfil sociodemogr?fico da popula??o alvo; transcri??o das entrevistas; categoriza??o das informa??es e an?lise ? luz da hermen?utica-dial?tica. O conceito de Sa?de do Trabalhador referido pelos sujeitos investigados, apesar de simplificado no tocante ?s especificidades dos trabalhadores, revelou-se com uma dimens?o ampla, com a perspectiva da abordagem do trabalhador no seu ?mbito f?sico, ps?quico e social, sugerindo uma boa apreens?o de acordo com o conceito ampliado de sa?de. Al?m disso, foi poss?vel afirmar o reconhecimento de uma atua??o ainda incipiente dos enfermeiros da Aten??o B?sica sobre a Sa?de do Trabalhador, cujo desempenho foi apontado como falho. Foram citadas, em geral, algumas a??es pontuais de Sa?de do Trabalhador realizadas nas unidades de sa?de. Outras atividades mostraram-se rotineiras, sendo realizadas por uma minoria de profissionais conscientes sobre a import?ncia e necessidade de atingir esses usu?rios, a fim de engaj?-los na rotina da unidade de sa?de. A maioria dos profissionais relatou a n?o abordagem da Sa?de do Trabalhador durante a gradua??o em enfermagem, destacando uma car?ncia no campo te?rico e pr?tico na ?rea
This study aims to analyze concepts and practices developed by nurses in occupational health in primary care, and it is justified by the need to expand knowledge of this thematic area. This is an analytical qualitative study carried out in primary care units of health districts of the city of Natal-RN, in one health unit in each neighborhood. Data collection was held from August to October 2014, through semistructured interviews, in the following order: Selection of respondents and scheduling of interview; interviews and application of data collection instrument in order to trace socio-demographic profile of the target population; transcription of interviews; categorization of information and analysis in light of hermeneutic-dialectic. The concept of Occupational Health reported by subjects investigated, although simplified with respect to specificities of workers, was revealed with a wide dimension, with perspective of workers? approach in their physical, mental and social context, suggesting a good seizure according to the expanded concept of health. Furthermore, it was possible to affirm the recognition of an incipient performance of primary care nurses on Occupational Health, whose performance was appointed as defective. In general, some specific actions of Occupational Health, carried out in health facilities, were cited. Other activities showed up to be routine, being held by a minority of professionals aware of the importance and need to reach these users, in order to engage them in the routine of the health unit. Most professionals reported not having approached Occupational Health during undergraduate nursing, highlighting a lack in theoretical and practical aspects of the area
Westlake, Elizabeth. "Learn to live and learn to die : Heinrich Suso's Scire Mori in fifteenth century England." Thesis, University of Birmingham, 1993. http://etheses.bham.ac.uk//id/eprint/2825/.
Full textBarreiros, André Mateus. "Estudo sobre a pedogênese na transição arenitos-basaltos na bacia do córrego gurupá (Floraí/PR)." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/8/8135/tde-12092013-110619/.
Full textThe goal of the present research is to show which pedogenetic processes take place in the genesis and evolution of soils in the northwest of the state of Paraná, aiming specifically on the formation of nitic horizons on top of latosolic horizons in a basaltic area, inserted in a lithological transition zone, between basalts and sandstones. The study area is the Gurupá Creek hydrographical basin, located in Floraí - PR. In this process, photointerpretation techniques and procedures were used for the geological survey, in order to elucidate the substratum´s distribution, landforms and associated soils. The final cartographic product is a Morpholithological Map. The Structural Analysis of the Pedological Coverage supplied us with the procedures which allowed the multi-scalar analysis of the organization and dynamics of the soil coverage. The pedological system studied in this research presents a sandy superficial volume, and an increase in clay content in the subsuperficial volumes, organized in polyhedral blocks or microaggregated structure, clearly distinguishable during the field work; the analysis of the physical and chemical parameters revealed a morphological difference between the quartz grains in depth and heterogeneous concentration of elements and oxides in the studied profiles. With the support of different concepts, techniques and procedures of soil micromorphology, we demonstrated that an intense geochemical dissolution of the quartz grains is currently taking place, in the form of dissolution gulfs, abundant plasmic separations in the contact of the sandy and argilic volumes, with an evolution in depth and intense illuviated clay accumulation in the subsurface, causing the reorganization of the microaggregated structure in polyhedral blocks, with an ascending evolution. In synthesis, this system evolves through the transportation of matter, which promotes reorganizations within the pedological coverage (elluviation/illuviation), indicating that the area is going through a period of pedobioclimatic imbalance.
Green, Johanna M. E. "Judgement Day I, Resignation A and Resignation B : a conceptual unit in the Exeter Book." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3725/.
Full textOhashi, Tadashi. "Utilização de quitina e mordente na remoção do corante preto Remazol B por adsorção." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266703.
Full textTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Química
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Resumo: Neste trabalho foi investigado o tratamento físico-químico para a remoção do corante reativo Preto Remazol B por adsorção utilizando quitina isolada de resíduo industrial (exoesqueleto de camarão). A extração da quitina foi feita a partir do resíduo industrial de exoesqueleto de camarão através do tratamento de descoloração com NaClO, seguido de desproteinização por álcali à temperatura de 100ºC e liofilização. A quitina obtida foi separada por granulometria, sendo selecionada para os estudos com adsorção a fração da malha 16. O processo de remoção do corante reativo Preto Remazol B foi utilizado como um novo método, aplicando a técnica de adsorção, com posterior laqueadura com soluções inorgânica e orgânica como mordentes, no sentido de aumentar e melhorar a fixação do corante hidrolisado. Um planejamento fatorial de dois níveis foi empregado para analisar a influência da velocidade de agitação, pH, tempo de adsorção e temperatura num sistema de banho finito, contendo uma solução do corante Preto Remazol B, operando em sistema de pressão ambiente. Nos experimentos, o volume do banho e as quantidades do adsorvente foram mantidas constantes em sistema aberto, sob agitação constante. A variação das velocidades foi planejada em baixa, média e alta agitação em Banho-Maria. Os resultados obtidos demonstraram que a adsorção realizada em temperatura elevada apresentou melhor rendimento nos tingimentos, como também no pH 3,0 do banho. O produto formado da complexação Preto remazol B e quitina foi separado da solução por decantação, sendo a quantidade do corante não adsorvida determinada por espectrofotometria em UV-Vis, usando uma curva de calibração do corante a 597nm. Os ensaios 11 e 13 respectivamente, indicaram absorbância zero a ? = 597 nm, sugerindo que, no tingimento propriamente dito, a eficiência de adsorção dos corantes ocorreu no meio ácido, e que outros fatores como tempo, temperatura e velocidade não influenciaram diretamente no rendimento. A operação pós-tingimento denominada de polimento, determinou definitivamente o resultado final da adsorção, onde o uso da solução de sulfato de alumínio a 2%, como mordente possibilitou maior adesão do corante reativo hidrolisado à quitina no banho de tintura. O novo tratamento físico-químico proposto removeu totalmente o corante do efluente têxtil, apresentando baixo custo, além de gerar um produto similar a não-tecido
Abstract: In this work was investigate the physical-chemical treatment for the removal Remazol Black B dye reagent by adsorption using chitin isolated from industrial waste (exoskeleton shrimp). The extraction of chitin was made from industrial waste of shrimp (exoskeleton of shrimp) in the decolorization treatment with NaClO, followed by deproteinization of alkali solution at temperature of 1000C, and freeze dried. The chitin were separated by granulometry corresponding to fraction mesh 16. The removal process of Remazol Black B dye was used a new method applying the technique of adsorption with subsequent ligation with inorganic and organic mordants solutions, in order to enhance and improve the fixing of dye hydrolyzate. A two -level of factorial design was employed to analyze the influence of stirring speed, the pH, and temperature in adsorption system containing a finite bath synthetic solution of Remazol Black B dye, operating in pressure system. In the experiments, the volume of the bath and the amount of the adsorbent were kept constant agitation. The ranges of speeds were planned in low medium and higher agitation in water bath. The results showed that the adsorption carried out at elevate temperature has a better efficiency in dyeing, but also the bath pH3.0. The product formed by complexation Remazol Black B and chitin was separated from the solution by decantation, and the amount of the dye do not adsorbed was determined by UV-Vis spectrophometer using a calibration curve in colorant at 597nm. The assays 11 and 13, respectively, indicated absorbance at ? = 597 nm zero, suggesting adsorption efficiency of the dyes takes place in acid médium, and other factors such as time, temperature and speed (rpm) do not directly influenced the process. The operation after dyeing called polishing definitively determine the final result of adsorption, where the use of aluminium sulphate solution at 2%, promoted greater adherence allowed hydrolyzate of the reactive dye in the bath and chitin, suggesting the new proposed physical-chemical treatment to removal dyes pigments from textile effluent, and showed low cost, beyond that generate similar to a non-woven
Doutorado
Sistema de Processos Quimicos e Informatica
Doutor em Engenharia Química
Charpin, Caroline. "Nouveaux auto-anticorps dans la polyarthrite rhumatoïde." Thesis, Aix-Marseille 2, 2011. http://www.theses.fr/2011AIX22128/document.
Full textRheumatoid arthritis (RA) is a chronic inflammatory disease with a prevalence of 0.5% wordwilde. HLA-DR genes are the strongest genetic prevalence in RA. The sera of RA patients contain many auto-antibodies. The most characteristic are directed at citrullinated proteins (ACPA). ACPA can be detected by commercially available enzyme-linked immune-absorbent assays using synthetic cyclic citrullinated peptides (CCP).1/In the first work we tested whether the presence of RA associated HLA-DRB1 alleles individually influences anti-CCP production in a population of RA from Marseille. We showed RA associated HLA-DR alleles are not mandatory for the production of anti-CCP. HLA-DRB1*04:04 was the most strongly associated with the presence of anti-CCP in RA sera. 2/ Anti-CCP antibodies are detected in 65% of RA patients. We wanted to detect new auto-antibodies for the diagnosis of RA.By screening protein arrays we found that B-Raf (v raf murine sarcoma viral oncogen homologue B1) is a major non-citrullinated auto-antigen recognized by 35% of RA patients’sera. B-Raf encodes a serine threonine-kinase involved in the MAPK signaling pathway. We showed that anti-B-Raf auto-antibodies activate the in vitro phosphorylation of MEK1 mediated by B-Raf.We found that one peptide of B-Raf, p25, is specifically recognized by auto-antibodies from RA patients. Of interest, anti-p25 auto-antibodies are detected in 21% of anti-CCP negative RA patients.3/We identified 24 new auto-antigens associated with RA patients with disease duration less than one year using 8000 human protein arrays. We identified four auto-antigens recognized almost uniquely by sera of early RA patients: GABA(A) receptor associated protein like, zinc finger protein 706, tropomyosin 2 and WIBG (within BGCN homolog (Drosophila)). These reactivities were confirmed by ELISA on purified proteins. Auto-antibodies to anti-WIBG identify exclusively RA patients’sera. These new auto-antigens could be used for the diagnosis of anti-CCP negative RA patients and in early RA
Dick, Maria-Daniella. "Dante ... Joyce : Derrida." Thesis, University of Glasgow, 2010. http://theses.gla.ac.uk/2494/.
Full textRobson, Julia Caroline. "The dialectic of self and other in Montaigne, Proust and Woolf." Thesis, University of Warwick, 2000. http://wrap.warwick.ac.uk/4372/.
Full textDeans, Alexander Eden Atkinson. "Labouring bodies, feeling minds : intellectual improvement and Scottish writing, 1759-1828." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6170/.
Full textFrizzo, Ta?s Cristine Ernst. "Educa??o e natureza : os desafios da ambientaliza??o em escolas pr?ximas a unidades de conserva??o." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2018. http://tede2.pucrs.br/tede2/handle/tede/8085.
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Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES
The aim of this research was to understand the relationship of schools and the place where they are inserted. The study investigated what factors can influence the environmentalization of schools' curriculum. An ethnographic approach was applied. The study was based on data collected in schools in Viam?o and Porto Alegre, in Brazil, which are located around conservation areas. The research identified that the main concern related to the environment in most schools were global issues, especially in regards to solid waste issues. In one of the schools analysed, it was identified a focus on the value of the school location and of the conservation area. Factors that influenced the environmentalization of the school?s curriculum were: the effects of public policy; the school documents; the presence of a conservation area next to the school and its relationship with the place; the agency of nonhuman actors and issues related to human actions and emotions, e.g. violence, the recognition of the nature and the concern with environment issues. The research also identified some elements that facilitated a connection between schools and the conservation areas, and other elements that, on the contrary, hampered or banned the access of students and educators in those areas. The factors that contributed to the relationship between schools and conservation areas were their geographic proximity; the efforts of managers and other staff in the conservation areas to promote environmental education in schools; the presence of educators and managers engaged with environmental issues, and the incentives of public policies addressing environmental education and sustainability. The challenges identified were related to the restricted number of staff in the conservation areas and to the limited financial resources available. Public policies can facilitate the relationship between schools and conservation areas however they can also make the process more difficult. Examples are the rules and orientations about the school curriculum, the rules for visitors in conservation areas and the historical conflicts related to the establishment of conservation areas in Brazil. Despite impositions and difficulties faced by schools, the creativity of the people and the influence of the place allow them to stand up to challenges related to the environmentalization of the curriculum.
O objetivo desta pesquisa foi compreender como a escola se relaciona com o lugar em que est? inserida, observando os fatores que podem influenciar a ambientaliza??o do curr?culo. Foi utilizada uma abordagem de inspira??o etnogr?fica, sendo estudadas escolas de Viam?o e de Porto Alegre, RS, localizadas no entorno de unidades de conserva??o. Observou-se que a maioria das escolas tinha como preocupa??o ambiental quest?es globais, principalmente no que se refere aos problemas associados aos res?duos s?lidos. Uma das escolas pesquisadas destacou-se pelo foco na valoriza??o do lugar e da unidade de conserva??o. Fatores como os efeitos de pol?ticas p?blicas; os documentos escolares; a presen?a de uma unidade de conserva??o pr?xima ? escola e as rela??es com o lugar; a ag?ncia de entidades n?o humanas e as quest?es oriundas das a??es e emo??es humanas, tais como a viol?ncia, a valoriza??o da natureza e a preocupa??o com a quest?o ambiental, estavam relacionados com a ambientaliza??o do curr?culo. Foram observados elementos que facilitavam a aproxima??o entre escolas e unidades de conserva??o e outros que, ao contr?rio, dificultavam ou impediam o acesso dos estudantes e dos professores nessas ?reas. Entre os fatores que contribu?ram nessa rela??o est?o a proximidade f?sica entre escolas e unidades de conserva??o; os investimentos dos gestores e funcion?rios das unidades de conserva??o na promo??o da educa??o ambiental nas escolas; a presen?a de professores e de gestores engajados com as quest?es ambientais e os incentivos das pol?ticas p?blicas para a educa??o ambiental e para a sustentabilidade. Entre os desafios observados est?o o n?mero reduzido de funcion?rios nas unidades de conserva??o e a pouca disponibilidade de recursos financeiros. As pol?ticas p?blicas podem facilitar a rela??o entre escolas e unidades de conserva??o, mas tamb?m podem dificultar esse processo. Exemplo disso s?o as normas e orienta??es sobre o curr?culo escolar, as regras para visitantes nas unidades de conserva??o e os conflitos hist?ricos relacionados ? implanta??o das unidades de conserva??o no Brasil. Apesar das imposi??es e dificuldades que chegam ?s escolas, a criatividade das pessoas e a influ?ncia do lugar permitem avan?ar no enfrentamento dos desafios relacionados ? ambientaliza??o do curr?culo.
Östrand, Therese. "Analysis of CHS, MEB5.2, PDX1.3 and PR-5 expression in Arabidopsis thaliana ecotypes during UV-B irradiation." Thesis, Örebro universitet, Akademin för naturvetenskap och teknik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-9733.
Full textAzevedo, Luciana Fernandes de Medeiros. "Nervos: rede de discursos e pr?ticas de cuidado na aten??o b?sica no munic?pio de Natal/RN." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17387.
Full textThe Primary Health Care and one of its main strategies, the Family Health Strategy (ESF), are framed as the gateway to the Public Health System (SUS). Thus, most of the incident and prevalent health problems in the population attended should be solved at this level of care, including psychological suffering, and the so-called complaint of nerves. Nerves and nervous denote a complexity that is not always well comprehended by health workers, in such a way that the care to this kind of problem is usually inadequate. In this line of thought, the general objective of this study is to analyze the network of discourses and the care to the psychological suffering, expressed as nerves, in SUS daily Primary Health Care. Besides and more specifically, it aims at identifying the principles and guidelines of the Primary Health Care in mental health; to investigate health workers positioning before psychological suffering and complaints of nerves, and also analyze different actions and practices of care carried out in different Health Units towards complaints like nerves. Institutional Ethnography was the theoreticalmethodological perspective adopted for the work. This approach seeks to understand and analyze the institutional relationships in a particular context considering sociostructural influences and power relations, as well as daily discourses and practices. Based on interviews with health professionals, informal conversations and observations in six Health Units with ESF teams from different sanitary districts in Natal/RN, it was possible to check that the index of complaint of nerves is high. The referral to psychologists and psychiatrists, as well as the prescription of psychotropic drugs appear as the most common intervention at this level of care. In general, the participants complain that they have poor specialized knowledge about the theme of mental health. They face the problem of bad work conditions and the lack of institutional support, which make actions of illnesses prevention and health promotion even more difficult. Besides, there are different ongoing practices such as meetings for hypertensive and aged people, walk, visit, round-table discussions and community therapy. However, not all of these actions are aimed at the care of psychological suffering. It is observed that the Matrix Support, which is a methodological strategy of supervision and follow up forcases of mental health, hasn t been totally implemented in the municipal system, although it is a tool that has been used by psychologists in some Health Units in the city. It was also verified that the health care practices to the problem of nerves strongly depend on the professional s commitment with the PSF guidelines and on mental health policies, in addition to continued support, when available, from other professional who works as matrix supporter
A aten??o b?sica e uma de suas principais estrat?gias, a Estrat?gia Sa?de da Fam?lia (ESF), se configuram como a porta de entrada para o Sistema ?nico de Sa?de (SUS). Dessa maneira, boa parte dos problemas de sa?de incidentes e prevalentes na popula??o dscrita deve ser resolvida nesse n?vel de aten??o, incluindo o sofrimento psicol?gico e a denominada queixa de nervoso. Nervos e nervoso denotam uma complexidade que nem sempre ? bem compreendida pelos trabalhadores de sa?de, de maneira que o cuidado a esse tipo de problema geralmente ? inadequado. O objetivo geral desse trabalho ? analisar a rede de discursos e de cuidados no atendimento ao sofrimento psicol?gico que se expressa como nervos, no cotidiano da aten??o b?sica do SUS. Mais especificamente, identificar os princ?pios e diretrizes da aten??o b?sica em sa?de mental; investigar o posicionamento dos trabalhadores de sa?de diante do sofrimento psicol?gico e das queixas de nervos, e analisar as diferentes a??es e pr?ticas de cuidado realizados nas diferentes Unidades de Sa?de diante de queixas como nervos. A perspectiva te?rico-metodol?gica adotada no trabalho foi a Etnografia Institucional. Essa abordagem busca compreender e analisar as rela??es institucionais em determinado contexto considerando as influ?ncias socioestruturais e as rela??es de poder, bem como as pr?ticas e os discursos cotidianos. Foram realizadas entrevistas com trabalhadores de sa?de, conversas informais e observa??es em seis Unidades de Sa?de com equipes da ESF de diferentes distritos sanit?rios do munic?pio de Natal/RN. Constatou-se o alto ?ndice de queixas de nervos, sendo que o encaminhamento a psic?logos e psiquiatras e a prescri??o de psicotr?picos s?o a forma mais comum de interven??o. Em geral, h? uma falta de conhecimento especializado sobre o tema da sa?de mental, bem como aus?ncia de discuss?es sobre as pol?ticas de sa?de mental. De um lado, as condi??es de trabalho e a falta de apoio institucional dificultam a realiza??o de a??es de preven??o de doen?as e promo??o ? sa?de. Por outro, h? diferentes pr?ticas em andamento tais como reuni?es de hipertensos e idosos, caminhadas, visitas, rodas de conversas e terapia comunit?ria embora nem todas visem o cuidado espec?fico ao sofrimento psicol?gico. O apoio matricial, estrat?gia metodol?gica de supervis?o e acompanhamento de casos de sa?de mental, vem sendo implantado por psic?logos em algumas Unidades de Sa?de do munic?pio, por?m ainda n?o est? totalmente implantado na rede. As pr?ticas de cuidado aos problemas de nervos dependem principalmente do envolvimento do trabalhador com as diretrizes da ESF e das pol?ticas de sa?de mental, al?m do apoio sistem?tico, quando dispon?vel, de outro profissional que funciona como apoiador matricial
Oligurski, Eliana Maria. "A possibilidade de incorporar a pesquisa na pr?tica cotidiana do professor do ensino fundamental." Pontif?cia Universidade Cat?lica de Campinas, 2009. http://tede.bibliotecadigital.puc-campinas.edu.br:8080/jspui/handle/tede/630.
Full textThis research aims to verify the possible link between teaching and research in teacher s work in basic education. The research was conducted in a Municipal Elementary School in the city of Campinas, with teachers and students of the first years of Elementary School. We analyzed documents, as the Pedagogical Project of the school and texts presented by students, and also interviewed students and teachers in order to clarify their conceptions of research. The results of this research point out that it is possible to develop a pedagogical practice in Elementary School articulating teaching and research, and taking research as a way to promote intellectual and integral development of students, as well as integration between school and its community. Nevertheless, to achieve this objective, it is necessary that the school, and the educational system as a whole, offer conditions for projects like the one exposed in this study to achieve success.
Esta pesquisa tem como objetivo verificar a poss?vel articula??o entre ensino e pesquisa na pr?tica pedag?gica do professor da educa??o b?sica. O estudo foi realizado em uma escola da Rede Municipal de Campinas-SP, com alunos e professores das s?ries iniciais do ensino fundamental, a partir da an?lise de documentos, como o Projeto Pol?tico Pedag?gico da Escola, e de trabalhos produzidos pelos estudantes. Foram tamb?m realizadas entrevistas e question?rios para an?lise das concep??es de pesquisa destes professores e alunos. Os resultados apontam que ? poss?vel desenvolver na escola b?sica uma pr?tica pedag?gica que articule ensino e pesquisa, tornando esta ?ltima uma fonte catalizadora de desenvolvimento integral e intelectual dos alunos, bem como de integra??o entre escola e comunidade. Para tal, no entanto, ? de fundamental import?ncia que a escola, e o sistema educativo como um todo, ofere?am condi??es para que propostas como as analisadas no presente estudo possam ser efetivadas.
Hoffmann, Lucia. "Associação entre o polimorfismo genético da apolipoproteína-B e fatores de risco cardíaco em pacientes da região dos Campos Gerais-PR." UNIVERSIDADE ESTADUAL DE PONTA GROSSA, 2012. http://tede2.uepg.br/jspui/handle/prefix/970.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
Apolipoprotein B (apoB) is the principal protein from low density lipoprotein (LDL) involved in cholesterol metabolism and transport. Single nucleotide polymorphisms (SNPs) in the human apoB gene have been associated with cardiovascular disease risk, such as Coronary Artery Disease (CAD), dyslipidemia and atherosclerosis. These multifactorial diseases are generated by interaction between environmental and genetic factors. Previous works investigated the genetic causative components of these diseases and focused mainly on polymorphisms that occur in genes encoding structural proteins and enzymes related to lipid profile. The present study aimed to investigate the MspI polymorphism in the apoB gene association with cardiovascular risk factors in a case-control patients group from the Campos Gerais region (Paraná, Brazil) population, moreover to determine this polymorphism allele and genotype frequencies, and also to associate the obtained genetic data with cardiac risk related variables by using correlation analysis. We evaluated 66 patients, from which 55 patients formed the cardiovascular risk group, and 11 others composed the group without risk – control. The patients mean age was 60 ± 10.0 years in the group with risk and 53 ± 14.0 years in the control group. The MspI polymorphism (exon 26) on apoB gene was characterized by PCR-RFLP and, after restriction, DNA fragments were identified by electrophoresis using agarose gel. The normal allele was named M1 and the mutated allele was called M2. The obtained values for MspI polymorphism genotypic frequencies were 0.82, 0.09, 0.09 for the control group, and 0.76, 0.24, 0.00 for the CAD risk group, respectively for genotypes M1M1, M1M2, M2M2. It was showed that the M1M1 homozygous was dominant in the genotype distribution for both groups. There was no significant difference between the allele and genotype frequencies for MspI polymorphism in the apoB gene (2 = 5.90, P > 0.05; Contingency Test) when comparing the two groups. Therefore, the distribution of the studied polymorphism in the Campos Gerais region population presented to be in Hardy-Weinberg equilibrium both for the control group and for the CAD risk patients group, keeping stable the polymorphism, what was already previously reported for Chinese and Korean populations. The Pearson correlation analysis performed between the risk variables (age, diabetes mellitus, high LDL, high triglycerides, low HDL, hypothyroidism, weight, body mass index) showed correlation between the most of the variables for M1M1 and M1M2 genotypes. But for the total population (n = 66), the association of the apoB gene polymorphism was not correlated with cardiac risk variables. In the end, this research presented data for understanding the association of apoB gene polymorphism with lipid metabolism disorder in the development of risk factors for cardiovascular disease in the population of Campos Gerais (PR).
A apolipoproteína B (apoB) é a principal proteína da lipoproteína de baixa densidade (LDL) que está envolvida no transporte e metabolismo do colesterol. Polimorfismos de único nucleotídeo (SNPs) no gene da apoB humana têm sido associados ao risco para doenças cardiovasculares, como a Doença Arterial Coronariana (DAC), as dislipidemias e a aterosclerose. Estas doenças são caracterizadas como multifatoriais, causadas pela interação entre fatores ambientais e genéticos. Estudos de investigação dos componentes genéticos causadores destas doenças têm focado principalmente em polimorfismos nos genes que codificam proteínas estruturais e enzimas relacionadas ao perfil lipídico. Este trabalho teve como objetivo investigar a associação do polimorfismo MspI no gene da apoB com os fatores de risco cardiovascular em um grupo de pacientes caso-controle na população da Região dos Campos Gerais (Paraná, Brasil), além de determinar as frequências alélicas e genotípicas deste polimorfismo, e associar os dados genéticos obtidos com as variáveis relacionadas aos riscos cardíacos através da análise de correlação. Foram avaliados 66 pacientes, dos quais 55 compuseram o grupo com risco cardiovascular, e os 11 demais formaram o grupo sem risco – controle. A idade média dos pacientes foi de 60 ± 10,0 anos no grupo com risco e 53 ± 14,0 anos no grupo controle. O polimorfismo MspI (exon 26) no gene da apoB foi caracterizado por PCR-RFLP, sendo os fragmentos de DNA, após a restrição, identificados por eletroforese em gel de agarose. O alelo normal foi denominado M1 e o alelo mutado M2. As frequências genotípicas encontradas para o polimorfismo MspI foram 0,82, 0,09 e 0,09 para o grupo controle; e 0,76, 0,24 e 0,00 para o grupo de pacientes com risco, respectivamente para os genótipos M1M1, M1M2 e M2M2. O homozigoto M1M1 foi predominante na distribuição genotípica para ambos os grupos. Não houve diferença significativa entre as frequências genotípicas e alélicas do polimorfismo MspI no gene da apoB (2 = 5,90; P > 0,05; Teste de Contingência), quando comparados os 2 grupos em estudo. Assim, a distribuição do polimorfismo estudado na população da região dos Campos Gerais (PR) se mostrou no equilíbrio de Hardy-Weinberg, tanto no grupo controle quanto no grupo de pacientes com risco cardíaco, mantendo o polimorfismo estável, sendo estes resultados também relatados para as populações chinesa e coreana. Na análise de correlação de Pearson entre as variáveis de risco (idade, diabetes mellitus, LDL alto, triglicerídios alto, HDL baixo, hipotireoidismo, peso, índice de massa corporal), observou-se que a maioria das variáveis analisadas se correlacionaram para os genótipos M1M1 e M1M2. Já para a população total estudada (n = 66), a associação do polimorfismo gênico da apoB não apresentou correlação com as variáveis de risco cardíaco. Enfim, esta pesquisa apresentou dados para o entendimento da associação do polimorfismo do gene da apoB com o distúrbio de metabolismo lipídico no desenvolvimento de fatores de risco para doenças cardiovasculares na população dos Campos Gerais (PR).
Damion, Marina. "N?cleo de apoio ? sa?de da fam?lia (NASF) : a pr?tica de psic?logas na aten??o b?sica." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2018. http://tede2.pucrs.br/tede2/handle/tede/7948.
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Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES
The purpose of this study is to understand how are configured the practices and the work processes of psychologists of NASF in the city of Porto Alegre and metropolitan region. The Family Health Support Center (NASF) has as main objective to qualify Primary Care and increase the resolution of care through multidisciplinary action and technical-pedagogical support with the inclusion of new nuclei of knowledge and strategies of care along with Family Health Teams (ESF). In this context, the insertion of at least one mental health professional in the NASF is also recommended, among them psychology professionals. In addition to mental health, psychology also promotes actions aimed at the health of the family and the territorialization of care, encountering contexts of complexity in the performance of basic care. The research that characterizes the empirical section of this dissertation consists of a qualitative, exploratory and descriptive study. The participants were six psychologists, aged between 29 and 45 years, working in NASFs in Porto Alegre and Metropolitan Region, invited by the snowball method, in which one professional indicates the next to participate. The inclusion criterion was that the participants worked for at least six months in the NASF. The instrument used in the data collection was a semi-directed interview, which was recorded in audio and transcribed. For the analysis of the material, Thematic Analysis technique was used, giving rise to three thematic axes of analysis, which were named: 1) Individual care: subjective health productions and their scope; 2) Me, them and us: interfaces between field and core; 3) The individual in the psychosocial perspective: specifics of the psychologist in NASF. The results point out that the practice of individual care is still an important aspect of NASF policy guidelines, so that the professionals attribute to this practice the professional responsibility and belonging to the specificity of their clinical identity. At the same time, it is pointed towards an approach of the clinic to the psychosocial and health promotion practices, which integrate the professional nuclei and make up a field performance. In this sense, we seek to problematize the NASF psychologist's practice in the current political context and the complexity of its performance.
O objetivo desse estudo ? compreender como se configuram as pr?ticas e os processos de trabalho dos psic?logos inseridos nos NASF na cidade de Porto Alegre e regi?o metropolitana. O N?cleo de Apoio ? Sa?de da Fam?lia (NASF) tem como objetivo principal qualificar a Aten??o B?sica e aumentar a resolutividade da aten??o, por meio da atua??o multidisciplinar e apoio t?cnico-pedag?gico com a inclus?o de novos n?cleos de saberes e estrat?gias de cuidado juntamente ?s Equipes de Sa?de da Fam?lia (ESF). Diante desse contexto, tamb?m se preconiza a inser??o de pelo menos um profissional da ?rea de sa?de mental no NASF, dentre eles profissionais da psicologia. Al?m da sa?de mental, a psicologia tamb?m promove a??es voltadas ? sa?de da fam?lia e ? territorializa??o do cuidado, deparando-se com contextos de complexidade na atua??o na aten??o b?sica. A pesquisa que caracteriza a se??o emp?rica desta disserta??o consiste em um estudo qualitativo, de car?ter explorat?rio e descritivo. As participantes foram seis psic?logas, com idades entre 29 e 45 anos, atuantes em NASFs de Porto Alegre e Regi?o Metropolitana, convidadas a partir do m?todo snowball, no qual um profissional indica o pr?ximo para participar da pesquisa. O crit?rio de inclus?o foi que as participantes atuassem por, pelo menos, seis meses no NASF. O instrumento utilizado na coleta de dados foi uma entrevista semi-dirigida, que foram gravadas em ?udio e transcritas. Quanto ? an?lise do material, utilizou-se a t?cnica de An?lise Tem?tica, dando origem a tr?s eixos tem?ticos de an?lise, as quais foram nomeadas: 1) Atendimento individual: produ??es subjetivas em sa?de e seus alcances; 2) Eu, eles e n?s: interfaces entre campo e n?cleo; 3) O individual na perspectiva psicossocial: especificidades do psic?logo no NASF. Os resultados apontam que a pr?tica do atendimento individual ainda constitui aspecto de importante discuss?o entre as diretrizes da pol?tica do NASF, de forma que os profissionais atribuem a essa pr?tica uma responsabilidade profissional e pertencente a especificidade da sua identidade cl?nica. Ao mesmo tempo, aponta-se para uma aproxima??o da cl?nica ?s pr?ticas psicossociais e de promo??o da sa?de, que integram os n?cleos profissionais e comp?em uma atua??o do campo. Nesse sentido, busca-se problematizar a pr?tica do psic?logo no NASF no contexto pol?tico atual e a complexidade da sua atua??o.
Mitsigkas, Neophytos. "Using novels in English language teaching in Cyprus." Thesis, University of Essex, 2016. http://repository.essex.ac.uk/19316/.
Full textKan, Tabitha G. "Renderings of the abyss : some changing nineteenth-century literary perceptions of the animal/human divide." Thesis, University of Essex, 2016. http://repository.essex.ac.uk/19458/.
Full textVieira, Otávio Augusto Ruiz Paccola. "Geologia da folha Guapiara 1:50000 (SG-22-X-B-II-2) /." Rio Claro, 2017. http://hdl.handle.net/11449/150504.
Full textOrientador: Antonio Misson Godoy
Banca: Washington Barbosa Leite Junior
Banca: Jefferson Cassu Manzano
Resumo: A Folha topográfica de Guapiara 1: 50000 (SG-22-X-B-II-2) situa-se no extremo sul do estado de São Paulo e compreende na porção central da Província Mantiqueira a faixa centro-sul do Cinturão Ribeira. O arcabouço geológico local envolve rochas da sequência metavulcanossedimentar do Supergrupo Açunguí, de idade meso- a neoproterozoicas metamorfizadas e deformadas no Neoproterozoico, associadas a rochas granitoides gerados durante os episódios colisionais ligados ao Ciclo Brasiliano e à formação do Supercontinente Gondwana. Na região, oito unidades litoestratigráficas principais foram mapeadas: metassedimentos da Formação Água Clara e dos grupos Votuverava e Itaiacoca de idade meso- a neoproterozoica, corpos graníticos neoproterozoicos representantes do Granito Três Córregos, corpos graníticos neoproterozoicos a cambrianos do Granito Capão Bonito, rochas sedimentares do Grupo Itararé, intrusivas básicas associadas a Formação Serra Geral e sedimentos recentes Quaternários. O quadro estruturalmetamórfico é determinado dominantemente pelo arranjo tectônico final neoproterozóico, evidenciado nas rochas epimetamórficas por uma evolução estrutural do tipo polifásica. As estruturas primárias S0, devido aos intensos processos de transposição das foliações dúctil e deformação milonítica, apresentamse preservadas de forma escassa em algumas áreas, com predomínio somente do acamamento gradacional reliquiar S0, nas áreas menos deformadas, a um bandamento tectônico nas re... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The Topographic Sheet of Guapiara 1: 50000 (SG-22-X-B-II-2) is located in the southernmost part of the state of São Paulo and comprises the central portion of the Mantiqueira Province, the central-southern belt of the Ribeira Belt. The local geological framework involves rocks from the metavulcanosedimentary sequence of the Açunguí Supergroup, meso to neoproterozoic metamorphosed age and deformed in the neoproterozoic, associated with granitoid rocks generated during the collisional episodes related to the Brasilian Cycle and to the formation of the Gondwana Supercontinent. In the region, eight main lithostratigraphic units were mapped: metasediments of the Água Clara Formation and the Votuverava and Itaiacoca Groups of meso-neoproterozoic age, neoproterozoic granite bodies representing the Três Córregos Granite, granite neoproterozoic bodies of the Capão Bonito Granite, sedimentary rocks of Itararé Group, basic effusives rocks associated with the Serra Geral Formation and recent sediments of the Quaternary. The structuralmetamorphic framework is dominantly determined by the final neoproterozoic tectonic arrangement, evidenced in the epimetamorphic rocks by a structural evolution of the polyphase type. The primary structures S0, due to the intense processes of transposition of ductile foliations and milonite deformation, are sparsely preserved in some areas, with predominance only of the relic gradation bedding of S0, in less deformed areas, to a tectonic banding in the regio... (Complete abstract click electronic access below)
Mestre
SANTOS, PATRICIA B. "Efeitos da adição de surfactante e moagem de alta velocidade em pós magnéticos à base de Pr-Fe-B obtidos via HDDR." reponame:Repositório Institucional do IPEN, 2011. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10044.
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Dissertação (Mestrado)
IPEN/D
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
Santos, M?rcia Zschornack Marlow. "O PIBID e a forma??o continuada de professores de ci?ncias biol?gicas : contribui??es para a pr?tica docente." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2016. http://tede2.pucrs.br/tede2/handle/tede/6984.
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Funda??o de Amparo ? Pesquisa do Estado do Rio Grande do Sul - FAPERGS
The present dissertation aims to approach the ongoing development of teachers and presents the findings of a survey consisting of 14 public school teachers in the Basic Education who act as supervisors of a Biology subproject in the Institutional Scholarship Program for Beginning Teachers (PIBID) in seven Higher Education Institutions of Rio Grande do Sul (RS). The purpose of this paper is to understand the impacts of the Institutional Scholarship Program for Beginning Teachers of the Biology subproject from different Higher Education Institutions for the ongoing development of the supervising teachers who work in the Basic Education schools in Rio Grande do Sul. In order to deepen the understanding about the contributions of PIBID to the ongoing development of teachers, an investigation of the teachers? perceptions from different mesoregions of the State has been proposed. According to the criteria set by the Brazilian Institute of Geography and Statistics (IBGE), Rio Grande do Sul (RS) is divided into seven mesoregions (Mid-Western; Mid-Eastern; Metropolitan area of Porto Alegre; Northeast; Northwest; Southeast; South-West), from where the subjects of this survey were taken. For this purpose, a Higher Education Institution in each region was chosen as a sample. The data were collected by means of semi-structured recorded interviews and transcribed accurately by the researcher and analyzed through Discursive Textual Analysis. As the results of the analysis, categories that show an encouraging overview regarding the positive aspects that the program may offer to the ongoing development of teachers came out, especially with regard to the supervisors who work directly with the program. The engagement with the PIBID proposals renew the interest and affection for teaching. According to the teachers? accounts, it is possible to observe significant changes in their teaching practice. From the activities carried out and developed in partnership with the scholars who supervise, we could notice that they adopted a more reflective attitude, reconsidering some perceptions and conceptions regarding their teaching performance. Therefore, from their personal accounts, it is possible to realize that the adoption of new methodologies and practices have become part of their teaching actions.
A presente disserta??o aborda a forma??o continuada de professores e apresenta os resultados de uma pesquisa envolvendo 14 professores da rede p?blica de educa??o b?sica que atuam como supervisores no subprojeto de Biologia do Programa de Bolsas de Inicia??o ? Doc?ncia (PIBID) em sete Institui??es de Ensino Superior do Rio Grande do Sul (RS). Tem como objetivo compreender as influ?ncias do Programa Institucional de Bolsas de Inicia??o ? Doc?ncia (PIBID) do subprojeto de Biologia de diferentes Institui??es de Ensino Superior para a forma??o continuada dos professores supervisores que atuam nas escolas de educa??o b?sica no Rio Grande do Sul. A fim de aprofundar a compreens?o em rela??o ?s contribui??es do PIBID para a forma??o continuada dos professores, prop?s-se investigar a percep??o dos docentes das diferentes mesorregi?es do Estado. De acordo com os crit?rios estabelecidos pelo Instituto Brasileiro de Geografia e Estat?stica (IBGE), o Rio Grande do Sul (RS) encontra- se dividido em sete mesorregi?es (Centro Ocidental Rio-grandense; Centro Oriental Riograndense; Metropolitana de Porto Alegre; Nordeste Rio-grandense; Noroeste Rio-grandense; Sudeste Rio-grandense e Sudoeste Rio-grandense), a partir das quais se estabeleceram os sujeitos da pesquisa. Para tanto, elegeu-se uma IES em cada regi?o para compor a amostra. Os dados foram coletados por meio de entrevistas semiestruturadas, gravadas em ?udio e transcritas fidedignamente pela pesquisadora, e foram analisados por meio da An?lise Textual Discursiva (ATD). Como resultados da an?lise emergiram categorias que vislumbram um panorama motivador relacionado ?s positividades que o programa pode oferecer ? forma??o continuada de professores, especialmente no que se refere aos supervisores que atuam diretamente com o programa. O envolvimento com as propostas do PIBID renovam o interesse e o gosto pela doc?ncia. Nos relatos dos professores, podem-se constatar mudan?as consider?veis em sua pr?tica. A partir das atividades engendradas e desenvolvidas em parceria com os bolsistas que supervisionam, percebeu-se que eles demonstraram adotar uma atitude mais reflexiva, reconsiderando algumas percep??es e concep??es em rela??o ao seu fazer profissional. Evidenciam, a partir de seus testemunhos, a ado??o de novas metodologias e pr?ticas que passaram a integrar suas a??es docentes.
Biart, Nicholas David. "A question of history." Thesis, University of Chichester, 1999. http://eprints.chi.ac.uk/941/.
Full textLuna, Camila Larissa Firmino de. "A criatividade na pr?tica pedag?gica de professores de M?sica atuantes na rede de educa??o b?sica de Natal/RN." PROGRAMA DE P?S-GRADUA??O EM M?SICA, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/24893.
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A presente pesquisa teve como objetivo compreender as concep??es e pr?ticas que caracterizam a a??o pedag?gica de professores que tem a criatividade como processo e objetivo de sua proposta de educa??o musical dentro do contexto escolar da cidade do Natal/RN. As reflex?es que nortearam a investiga??o est?o fundamentadas em autores que abordam os aspectos referentes ? criatividade em geral, o indiv?duo criativo, o processo de cria??o (NACHMANOVICTH, 1993; GARDNER, 1996) ? incluindo o processo criativo musical ?, as motiva??es envolvidas nesse processo (REEVE, 2006), e a forma??o e atua??o pedag?gica do professor criativo (ABRAH?O, 2015; SCHAFER, 1991). As concep??es constru?das a partir da fundamenta??o te?rica baseiam-se na ideia de que, para criar, o indiv?duo necessita ter o dom?nio sobre os elementos a serem usados na cria??o, assim como a viv?ncia de experi?ncias que lhe subsidiam na a??o de gerar novos produtos, e o conhecimento sobre o processo criativo, que lhe permite persistir na trajet?ria at? que chegue ao produto final. Sobre a quest?o pedag?gico-musical especificamente, as ideias que fundamentam a investiga??o s?o aquelas que tratam a criatividade como um elemento fundamental para o exerc?cio da profiss?o. O m?todo de pesquisa escolhido foi o estudo de caso, utilizando como ferramentas de coleta de dados o question?rio, a observa??o direta e a entrevista semiestruturada. A an?lise dos dados se deu, primeiramente, de forma quantitativa e qualitativa, quando analisadas as respostas colhidas a partir do question?rio. Posteriormente, a abordagem qualitativa se sobrep?s na an?lise das etapas seguintes, quando os dados foram organizados em tr?s categorias: 1. As concep??es dos professores; 2. As caracter?sticas dos professores; e 3. As pr?ticas criativas realizadas. Os resultados apresentam alguns fatores relevantes sobre o processo criativo do professor, a fim de possibilitar a reflex?o de que todos possuem a condi??o e a possibilidade de criar, desde que se permita e possua o conhecimento sobre o processo criativo (NACHMANOVICTH, 1993). Al?m disso, as reflex?es realizadas a partir da rela??o entre a abordagem dos autores te?ricos e os dados emp?ricos coletados, visam promover uma inquieta??o no que tange a forma??o inicial dos educadores musicais, e a sua posterior atua??o pedag?gica.
The present work had the purpose of understanding the conceptions and practices that characterizes the pedagogical action of teachers that has the creativity as a process and aim of their musical education proposal in Natal/RN school context. The reflections that guided us are based on authors who deal with aspects related to creativity in general, the creative individual, the creative process (NACHMANOVICTH, 1993; GARDNER, 1996) - including the creative musical process - the motivations involved in this process (REEVE, 2006), and the training and pedagogical performance of the creative teacher (ABRAH?O, 2015; SCHAFER, 1991). Our concepts, built from the theoretical background, are based on the idea that, to create properly, the individual needs to have control over the elements to be used in creation, as well as the grasp of experiences that support him in the action of generating new products, and knowledge about the creative process, which allows it to persist in the path until it reaches the final product. On the pedagogical-musical question specifically, the ideas the investigation are based upon are those that treat the creativity as a basilar element for the exercise of the profession. The research method chosen was the case study, using as a data collection tool the questionnaire, direct observation and semi-structured interview. Data were analyzed first, in a quantitative and qualitative way, when the answers collected from the questionnaire were analyzed. Afterwards, the qualitative approach was set before in the analysis of the following stages, when the data were organized into three categories: 1. The conceptions of teachers; 2. The characteristics of teachers; and 3. The creative practices. The results present some relevant factors on the creative process of the teacher that allow us to reflect that all have the condition and the possibility of creating, if the knowledge about the creative process is endowed and permitted (NACHMANOVICTH, 1993). Furthermore, the reflections based on the relationship between the theoretical authors' approach and the empirical data collected, drive us to prosecute a concern about the initial formation of musical educators and their subsequent pedagogical performance.
SOARES, EDSON P. "Caracterização magnética e microestrutural de ímãs sinterizados de Pr-Fe-B processados pela técnica de transferência de pós e utilizando decrepitação por hidrogênio." reponame:Repositório Institucional do IPEN, 2005. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11263.
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Dissertacao (Mestrado)
IPEN/D
Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
Marcondes, Paulo Victor Prestes. "Estudo do controle das propriedades magneticas de liga a base de terras-raras, Pr (Nd) - Fe-B-Cu, por forjamento uniaxial a quente." reponame:Repositório Institucional da UFSC, 1995. https://repositorio.ufsc.br/xmlui/handle/123456789/157904.
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A presente tese se enquadra na área de materiais magneticamente duros e estuda o forjamento uniaxial a quente de ligas fundidas, Pr(Nd)-Fe-B-Cu, para produzir uma orientação preferencial do eixo-C, eixo de fácil magnetização, durante a prensagem na direção de forjamento. O forjamento uniaxial a quente possui a grande vantagem de não envolver o estágio de trabalho com o material na forma de pó. Nesse processo, somente um passo de deformação após o lingote ser fundido e dois simples tratamentos térmicos são necessários para se ter um bom produto final, o que se diferencia dos complicados passos da metalurgia do pó.
BUSSIERE, THIERRY. "Les tendinites du genou chez le sportif : revue de la litterature ; revison de 104 cas ; travail du service de chirurgie orthopedique et du centre de medecine du sport ; pr j.-l. lerat, pr b. moyen, dr e.brunet-guedj." Lyon 1, 1990. http://www.theses.fr/1990LYO1M163.
Full textPais, da Cunha Adérito Tomás. "Overcome of grape chemical barriers by the fungal pathogen Botrytis cinerea." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3425334.
Full textDurante l’infezione dell’uva il fungo fitopatogeno Botrytis cinerea incontra tessuti particolarmente ricchi di polifenoli e proteine PR e dove si accumula la fitoalessina trans-resveratrolo. Per simulare condizioni simili a quelli trovati negli acini d'uva, B. cinerea è stato coltivato in vitro con proteine e polifenoli estratti da uve mature, e con trans-resveratrolo. I risultati hanno dimostrato che in presenza di livelli tossici di trans-resveratrolo, i polifenoli dell'uva favoriscono una normale crescita del patogeno mentre le proteine consentono un parziale recupero della crescita. Le combinazioni polifenoli-resveratrolo o resveratrolo-proteina inducevano il rilascio di una forte attività laccasica nel mezzo, che sembra essere coinvolta nella disintossicazione del trans-resveratrolo. I risultati hanno di mostrato anche che il pattern delle proteine dell’uva era alterato durante la crescita del fungo. Infatti, le proteine dell’uva scomparivano rapidamente dalla coltura nella quale polifenoli e trans-resveratrolo erano presenti simultaneamente. Profili proteici simili sono stati ottenuti in vitro, incubando proteine con polifenoli dell'uva e /o trans-resveratrolo con le laccasi purificata di B. cinerea. In queste condizioni, la maggior parte delle proteine diventava insolubile. Questo pattern era molto simile a quello osservato negli acini infettati da B. cinerea. Pertanto, B. cinerea, attraverso la secrezione di attività laccasica e sfruttando i polifenoli, neutralizza facilmente la tossicità delle fitoalessine stilbeniche e rende le proteine PR insolubili. L'effetto di laccasi è stato studiato anche sulla germinazione delle spore di B. cinerea. Il resveratrolo da solo inizialmente non inibiva la germinazione delle spore, invece, la sua pre-incubazione con le laccasi, inducendo la formazione di trans-ε-viniferina, ne inibiva la germinazione. Invece se nel mezzo erano presenti anche i polifenoli non si osservava alcuna inibizione della germinazione. Successivamente è stato indagato il coinvolgimento delle proteasi di B. cinerea nella degradazione delle proteine d’uva. Del mezzo coltura è stata purificata una aspartyl e una tripeptidyl proteasi. Queste proteasi sono state in grado di degradare parzialmente le proteine d’uva. Un’analisi di espressione dei geni delle famiglie di tripeptidyl e aspartyl proteasi ha dimostrato anche altri membri di queste famiglie erano espresse in presenza di proteine PR dell’uva. I risultati permettono di concludere che nell’acino d’uva, caratterizzato d’una grande varietà di polifenoli, la laccasi non solo anulla la tossicità del trans-resveratrolo, ma modifica anche la solubilità delle proteine dell'uva. Questo effetto potrebbe facilitare l’azione proteasica del fungo verso le proteine PR d’uva.
Ferreira, Eliner Affonso. "Estudo das propriedades magnéticas e da microestrutura em ímãs permanentes à base de Pr-Fe-B-Co-Nb obtidos pelo processo HD e HDDR." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/85/85134/tde-18082009-162039/.
Full textSintered magnets have been produced with powder obtained using the hydrogenation, disproportionation, desorption and recombination (HDDR) process. The HDDR process for the production of the sintered magnets has been adopted in an attempt to reduce the milling time and to investigate its effect on the magnetic properties and microstructure. Commercial cast ingot alloys based on the compositions Pr14Fe75.9CoxB6Nb0.1 (x = 0; 4; 8; 10; 12; 16) and Pr20.5Fe72.5B5Cu2.0 (sintering aid) have been employed in this investigation. The HDDR powder was used to produce sintered magnets with a mixture of these alloys (alloy main + sintering aid), in the following proportion: 80%wt of the main alloy and 20%wt of the sintering aid. Standard hydrogen decrepitation (HD) magnets have also been included in this work for a comparison (milling time: 20, 15, 10, 5 hours). The sintering temperature and time were kept constant for all magnets (1050ºC for 1 hour). The sintered magnet produced using the process HD exhibited the best remanence (1220 mT). It was prepared with the Pr14Fe67.9Co4B6Nb0.1 alloy using a milling time of 20 hours. The best intrinsic coercivity was achieved with the Pr14Fe67.9Co4B6Nb0.1 magnet in both processes, namely: 1020 mT for the HDDR process with 5 hours of milling time and 1190 mT for the HD process with 20 hours of milling time. The microstructures of the permanent magnets have been investigated by scanning electron microscopy and energy dispersive X-ray analysis.
BARBOSA, LUZINETE P. "Estudo das propriedades e microestrutura de ímãs permanentes de Pr-Fe-B-(Co-Nb) preparados pelo processo de hidrogenação, desproporção, dessorção e recombinação (HDDR)." reponame:Repositório Institucional do IPEN, 2005. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11280.
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Tese (Doutoramento)
IPEN/T
Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
FERREIRA, ELINER A. "Estudo das propriedades magnéticas e da microestrutura em imãs permanentes à base de Pr-Fe-B-Co-Nd obtidos pelos processos HD e HDDR." reponame:Repositório Institucional do IPEN, 2008. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11694.
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Dissertação (Mestrado)
IPEN/D
Instituto de Pesquisas Energéticas e Nucleares - IPEN/CNEN-SP
Franco, Vinicius Cappellano De. "Estudo das propriedades magnéticas e estruturais de (Nd, Pr) FeB nanocristalino com adição de TiC e Cr." reponame:Repositório Institucional da UCS, 2009. https://repositorio.ucs.br/handle/11338/477.
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The addition of both Ti and Cr-C refine the grains in nanocomposites of Nd-Fe-B, increasing substantially the coercive field Hc . This motived our investigation of the effect of the addition of Ti-C and Cr to nanocomposites of Pr-Fe-B and Nd-Fe-B. Ribbons compositions (Pr9,5Fe84,5B6)0,97-x(TiC)0,03Crx (x = 0; 0,0025; 0,005; 0,0075; 0,01) and (Nd9,5Fe84,5B6)0,97-x (TiC)0,03Crx (x = 0,005; 0,01) were produced by melt-spinning. Magnetization measures in fields up to 90 kOe showed that materials containing Cr have substantially higher Hc than the other materials without Cr. For a Pr nanocomposites with 1% Cr, the coercive field Hc was 12.5 kOe, while for a Pr nanocomposites with 0% Cr, Hc = 5.1 kOe. For the sample with 1% Cr, the maximum energy product was approximately 13.6 MGOe, a value limited by the remanence. The X-ray diffractogram analysis showed that the ribbons based on Pr-Fe-B with 1% Cr consist basically of a Pr2Fe14B hard phase and an α-Fe soft phase. Mössbauer spectroscopy was performed at 300 K and showed a reduction of the hyperfine field due to the addition of Cr. Transmission electronic microscopy of the Pr-Fe-B sample with 1% Cr showed that the nanocomposites have a grain size larger than the material without Cr, the microstructure consisting of α Fe grains, with an average size of 100 nm, in a matrix of Pr2Fe14B.