Relevant bibliographies by topics / Azetidinone

Academic literature on the topic 'Azetidinone'

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Published: 9 March 2023

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Journal articles on the topic "Azetidinone"

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AL-Tamimi, Entesar Obeed, Raad Mahjoub Muslih, and Khalida Ali Thejeel. "Synthesis, Characterization and Antibacterial Studies of 2-azetidinones Compounds Derived from Amoxicillin." Al Mustansiriyah Journal of Pharmaceutical Sciences 15, no. 1 (June 1, 2015): 14–23. http://dx.doi.org/10.32947/ajps.v15i1.160.

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In this study, the new azetidinones were synthesized from Schiff bases 2(a-j) that derived from amoxicillin (1) on treatment with chloroacetyl chloride in presence of triethylamine gave azetidinone 3(a-j). The structure of these compounds have been elucidated on the basis of their physical and spectral. Azetidinone compounds were also screened for their antibacterial activity against some bacterial species using amoxicillin as standard.
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Alcaide, Benito, Pedro Almendros, Teresa Martínez del Campo, and Teresa Naranjo. "Gold-catalyzed preparation of annelated 2-azetidinones via divergent heterocyclization of enyne-tethered oxazolidines." Organic Chemistry Frontiers 5, no. 5 (2018): 817–21. http://dx.doi.org/10.1039/c7qo00950j.

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The divergent and selective syntheses of two types of annelated β-lactams, namely, furan- and tetrahydropyridine-fused 2-azetidinones, have been accomplished directly from 2-azetidinone-tethered oxazolidine-enynes through gold catalysis.
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Bhat, Ishwar, Sunil Chaithanya, P. D. Satyanarayana, and Balakrishna Kalluraya. "The synthesis and antimicrobial study of some azetidinone derivatives with the para-anisidine moiety." Journal of the Serbian Chemical Society 72, no. 5 (2007): 437–42. http://dx.doi.org/10.2298/jsc0705437b.

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Azetidinones were synthesized from p-anisidine in two steps. First the Schiff's bases were prepared by reacting the hydrazide of an anisidine derivative with different aromatic aldehydes. Cyclocondensation of the Schiff's bases with chloroacetyl chloride in the presence of triethylamine resulted in the formation of the corresponding azetidinone analogues. The structures of the newly synthesized compounds were confirmed by IR, 1H NMR and mass spectroscopic analysis. The antibacterial and antifungal potential of the synthesized compounds were evaluated by the agar disc method.
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Baruah, Shyamal, Amrit Puzari, Farhana Sultana, and Jayanta Barman. "Synthesis, Characterization and Evaluation of Antimicrobial Properties of (R)-(-)-4-Phenyl-2 Oxazolidinone Based Azetidinones." Anti-Infective Agents 16, no. 2 (August 3, 2018): 104–13. http://dx.doi.org/10.2174/2211352516666180619153317.

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Introduction: A series of (R)-(-)-4-Phenyl-2 oxazolidinone based azetidinones (4a-i) were synthesized from the reaction of (2-Oxo-4-phenyl-oxazolidin-3-yl) acetic acid with aromatic imines (3a-i) in the presence of Thionyl chloride and Triethylamine as a base. Methods: The transformation proceeds through the formation of acid chloride to ketene which finally forms the azetidinones through [2+2] cycloaddition with aromatic imines. Products obtained were screened to evaluate their antibacterial activity with respect to known bacteria like Escherichia Coli (E. Coli) and Bacillus subtilis. Results and Conclusion: In most of the cases, azetidinones were found to exhibit superior antimicrobial properties than oxazolidinones. They were found to be a good inhibitor of gram-positive and gramnegative bacteria. Enhancement of antibacterial property can be attributed to the presence of azetidinone ring and hydrophobic alkyl side chain in the scaffolds.
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O. Spry, Douglas, Nancy J. Snyder, Anita R. Bhala, Carol E. Pasini, and Joseph M. Indelicato. "Azetidinone Imides." HETEROCYCLES 26, no. 11 (1987): 2911. http://dx.doi.org/10.3987/r-1987-11-2911.

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Yamamoto, Shunzo, Akihide Kanetsuki, Yoshimi Sueishi, and Norio Nishimura. "Mercury-Photosensitized Decomposition of 2-Azetidinone and 4,4-Dimethyl-2-azetidinone." Bulletin of the Chemical Society of Japan 63, no. 10 (October 1990): 2911–15. http://dx.doi.org/10.1246/bcsj.63.2911.

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Patel, H. S., and H. D. Desai. "Synthesis of Some New Azetidinone Derivatives Containing Aryl Sulfonyloxy Group." E-Journal of Chemistry 1, no. 4 (2004): 194–98. http://dx.doi.org/10.1155/2004/258752.

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Some novel azetidinone derivatives containing aryl sulfonyloxy group have been prepared. The 4-sulfonyloxy aniline derivative (2) has been prepared by reaction of 4-nitro phenol (sodium salt) with N-acetyl sulfanilyl chloride (ASC) followed by hydrolysis by ethanolic HCl. This compound (2) undergoes facile condensation reaction with aromatic aldehydes to yield different Schiff’s bases (3a-h). Cyclocondensation of compounds (3a-h) with chloro acetyl chloride yields different 2-azetidinone derivatives (4a-h).
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Kapadiya, Khushal M., Dipti H. Namera, Kishor M. Kavadia, and Ranjan C. Khunt. "Synthesis of Benzthiazole Derivatives Grouping with Substituted Azetidinone Ring and its Functional Behaviour." International Letters of Chemistry, Physics and Astronomy 30 (March 2014): 223–32. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.30.223.

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A series of Schiff derivatives (5a-q) and azetidinone by way of amide linkage analogues (6a-q) containing 2-amino benzthiazole have been synthesized. Amide linkage were adapted from acid via reaction with hydrazine hydrate followed by reaction with different substituted aldehyde derived various Arylidene derivatives comprising with various donor and acceptor functional group. The structures of the new synthesized azetidinone derivatives were characterized on the basis of 1H-NMR, Mass, IR and elemental analysis data.
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Kapadiya, Khushal M., Dipti H. Namera, Kishor M. Kavadia, and Ranjan C. Khunt. "Synthesis of Benzthiazole Derivatives Grouping with Substituted Azetidinone Ring and its Functional Behaviour." International Letters of Chemistry, Physics and Astronomy 30 (March 12, 2014): 223–32. http://dx.doi.org/10.56431/p-9ap77z.

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A series of Schiff derivatives (5a-q) and azetidinone by way of amide linkage analogues (6a-q) containing 2-amino benzthiazole have been synthesized. Amide linkage were adapted from acid via reaction with hydrazine hydrate followed by reaction with different substituted aldehyde derived various Arylidene derivatives comprising with various donor and acceptor functional group. The structures of the new synthesized azetidinone derivatives were characterized on the basis of 1H-NMR, Mass, IR and elemental analysis data.
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Hauer, Jan, and Jan Šebenda. "Preparation and polymerization of 3-(2-adamantyl)-3-methyl-2-azetidinone." Collection of Czechoslovak Chemical Communications 50, no. 2 (1985): 454–58. http://dx.doi.org/10.1135/cccc19850454.

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3-(2-Adamantyl)-3-methyl-2-azetidinone (VI) was prepared, and new compounds, namely, methyl 2-(2-adamantyl) cyanoacetate, methyl-2-(2-adamantyl)-2-cyanopropanoate and methyl-2-(2-adamantyl)-2-methyl-3-aminopropanoate, were prepared in the course of the synthesis as intermediates. The anionic polymerization of lactam VI gave a polymer which was characterized by intrinsic viscosity, solubility, melting temperature and its IR and 1H NMR spectra. Compared with 3-butyl-3-methyl-2-azetidinone, lactam VI polymerizes much more slowly.
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Dissertations / Theses on the topic "Azetidinone"

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Gollins, David William. "The use of 2-azetidinone-4-carboxylic acid as a chiral synthon." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386889.

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ABBIATI, GIORGIO. "Reazioni di cicloaddizione tra 1,3-diazabuta-1,3-dieni e cheteni:sintesi di diidropirimidinoni e 4-immino-azetidinoni." Doctoral thesis, Università degli Studi di Milano, 2000. http://hdl.handle.net/2434/651275.

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The work of this Ph.D. thesis is an in depth study on [4+2] and [2+2] cycloaddition reactions of 1-(4-methylphenyl) and 1-benzyl-1,3-diaza-1,3-butadienes with different ketenes, usually generated from the corresponding acid halide in the presence of a base. Reaction with phenyl, diphenyl, chloro and ethoxycarbonylketenes are described and the mechanism involved is discussed. Moreover, thermal and photochemical ring expansion reactions of azetidinones to 5,6-dihydro-3H-pyrimidin-4-ones are studied. Finally, the [2+2] cycloaddition reactions of 1-benzyl-2,4-diphenyl-1,3-diaza-1,3-butadiene with some chiral ketenes, such as beta-(dimethylphenylsilyl)ketene, beta-menthoxyketene and Evans-Sjögren ketene are investigated. The results are analysed and rationalized also on the basis of computational calculations.
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Burtoloso, Antonio Carlos Bender. "3-azetidinonas e 3-azetidinois : preparação e aplicações na sintese de azetidinas substituidas." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249762.

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Murphy, Deirdre M. "STUDIES OF THE METALLO BETA LACTAMASE CCrA FROM BACTERIODES FRAGILIS AND A DANSYLATED MONOCYCLIC BETA LACTAM (1-(5-DIMETHYLAMINO-1-NAPTHALENESULFONYL HYDRAZIDO)-3-ACETAMIDO-4-METHOXY-2-AZETIDINONE." University of Cincinnati / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin990561318.

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Sharma, Madan Kumar. "Approaches to 3,3-disubstituted azetidinones." Thesis, University of Ottawa (Canada), 1990. http://hdl.handle.net/10393/5577.

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Chapter 1 contains a very brief overview of 3,3-disubstituted azetidinones. Also included in this chapter are the approaches to 'hybrid' azetidinones, i.e. those which contain the structural features of more than one class of azetidinones. Finally the target molecules for the present studies are listed. Chapter 2 contains details of use of various 2,3-dihydroxybutyric acid derivatives in enantioselective syntheses of 3-alkoxyazetidinones with an additional substituent at position 3. In chapter 3 similar studies on threonine derivatives for the syntheses of 3-amino-3-hydroxyethylazetidinones are described. These studies were only partially successful. In chapter 4 a systematic approach towards the syntheses of 3-alkoxyazetidinones is described. The steps involved were the formation of the C-3 carbanion from the parent azetidinones, reaction with acetaldehyde, oxidation of the resulting 3-alkoxy-3-hydroxyethylazetidinones and finally the reduction of the acetyl compound in a non-chelation controlled manner. It has been possible to synthesize protected 3-amino-3-hydroxyethylazetidinones by a similar series of reaction and the results are presented in chapter 5. Chapter 6 has details of syntheses of 3-hydroxy, 3-hydroxy-3-hydroxyethyl, 3-hydroxy-3-allyl and 3-$\sp\prime$epoxy$\sp\prime$azetidinones. Chapter 7 contains results of a detailed study on the impact of various variables on the non-chelation controlled reduction of 3-acylazetidinones (which have an additional substituent at 3-position). Chapter 8 is about the use of N, N-dimethylchloromethylenimnium chloride for the purpose of activating carboxylic acids for their final conversion to azetidinones. An attempt was made to determine the nature of the white solid obtained on reaction of DMF with oxalyl chloride, and the product of reaction between this white solid and a carboxylic acid.
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Pearson, Christopher I. "Lithiated azetidine and azetine chemistry." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:cf3c942f-80de-4092-a38d-11006ccbb9ce.

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This work describes developments in new azetidine and azetine chemistry; specifically, methods developed for the introduction of functionality α- to nitrogen in both ring systems, with additionally in situ formation of the latter system, from azetidine substrates. Chapter 1 discusses the growing importance of azetidines, and the current methods available for making substituted azetidines by ring formation. Further discussion comprises of current sp3 C–H activation approaches α- to nitrogen in heterocyclic compounds as potential methods for sp3 C–H activation on azetidines to give substituted azetidines. Previous work by the Hodgson group in this area is detailed. Chapter 2 describes the advance made towards 2,3-disubstituted azetidines using the thiopivaloyl protecting/activating group, where the latter plays a key role. Optimisation, scope, selectivity and mechanistic insight into the α-deprotonation–electrophile trapping of a 3-hydroxy azetidine system is discussed, which successfully gives access to a range of 3-hydroxy-2-substituted azetidines. Preliminary investigations with 3-alkyl-2-substituted azetidines are also described. Chapter 3 describes the development of a straightforward protocol to make 2-substituted-2- azetines, a rarely studied and difficult to access 4-membered azacycle subclass, from readily accessible azetidine starting materials using α-deprotonation–in situ elimination followed by further α-lithiation–electrophile trapping. Extension of this methodology by transmetallation from the intermediate organolithium to the organocuprate, resulting in greater electrophile scope, is also described.
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Shimamoto, Yasuhiro. "Exploration of New Reactivities of Azetidinols and Alkynylborates." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188616.

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Lenagh-Snow, Gabriel Matthew Jack. "The synthesis of azetidine and piperidine iminosugars from monosaccharides." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:207235d5-2ea5-4724-92fd-924fa0ccd4ed.

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Iminosugars are polyhydroxylated alkaloids, and can be generally defined as sugar mimetics in which the endocyclic oxygen atom has been replaced with a basic nitrogen. A common affect of this atomic substitution is to bestow these compounds with the ability to inhibit various sugarprocessing enzymes; most significantly the glycosidases (glycoside hydrolases) which areintimately involved in a huge array of biological functions. Compounds which inhibit these enzymes concordantly possess much potential as medicinal agents for the treatment of a variety of diseases. Several iminosugars have already achieved market approval as drugs, and many more are promising candidates in the late stages of clinical development. As such there remains considerable interest in this class of compound, both in terms of the exploration of novel iminosugar structures, as well as the continual development of more efficient general methodology for their synthesis. The densely-packed functionality and stereochemical information present in iminosugars makes them challenging targets for asymmetric chemical synthesis, whereas carbohydrates are clearly very attractive as chiral-pool starting materials for this purpose. Indeed, the majority of the most successful syntheses of iminosugars use the latter approach, and such is the focus of this thesis. Chapter 1 presents a relatively brief introduction to iminosugars, including their types of structure, natural occurrence and biological mode of action. The rationale behind their use as therapeutic agents for the treatment of some significant disease targets is also discussed. Chapter 2 is concerned with the preparation of a number of novel polyhydroxylated azetidines, and their evaluation as glycosidase inhibitors. Such compounds represent an almost entirely neglected class of iminosugars within the literature. An overview of natural and synthetic products incorporating an azetidine motif is given, as well as a brief review of preparative methods and known azetidine iminosugars. A highly efficient and flexible method for the key azetidine ring formation is demonstrated by the cyclisations of 3,5-di-O-triflates of pentoses and hexoses, and of a 2,4-di-O-triflate of glucose, with various primary amines. In this manner, many azetidine triols and tetrols were prepared in good yield. Furthermore, this process is readily adaptable to the installation of added functionality to the azetidine scaffold, as demonstrated by the preparation of 1-acetamido analogues. The initial biological screening of these compounds showed a promising array of glycosidase inhibition, including that of selective inhibition of fungal enzymes. Chapter 3 describes a strategy with which to prepare all sixteen stereoisomers of a known piperidine iminosugar, alpha-homonojirimycin (alpha-HNJ), in a highly divergent manner from just four of the possible thirty-two 6-azidoheptitols using traditional chemical synthesis in tandem with biotechnological transformations. One half of the execution of this strategy is described in this thesis. Two 6-azidoheptitols were prepared from D-mannose, thereby providing access to four 6-azidoketoheptoses through a combination of microbial oxidation and enzymatic epimerisation. Catalytic hydrogenation of these 6-azidoketoheptoses furnished four diastereomeric mixtures of 2,6-iminoheptitols, with varying degrees of stereoselectivity. Purification of these mixtures allowed six 2,6-iminoheptitols to be isolated, two of which have never previously been tested for glycosidase inhibition. Significantly, one of them was found to be a potent and highly selectiveinhibitor of alpha-galactosidases, and may therefore be of interest in the treatment of Fabry disease.
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Khan, Rehana Akhter. "Inheritance of azetidine-2-carboxylic acid resistance in Arabidopsis thaliana." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186585.

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A number of hypotheses link salt tolerance in plants to proline accumulation or transport of proline. To begin to understand the genetic basis of this correlation, fifteen mutants of Arabidopsis thaliana were selected for resistance to the toxic proline analog, azetidine-2-carboxylic acid (ACA). These mutants were characterized by seedling growth and proline content on nutrient agar media in the absence and presence of ACA and NaCl. One of these ACA-resistant mutants, KG3, also showed enhanced tolerance to NaCl and was characterized by a recessive trait, transparent testa. Inheritance studies indicated that ACA resistance in KG3 was due to a single recessive gene mutation, named aca1. Genetic mapping studies were done by crossing KG3 with a morphological marker line W100 to determine the chromosomal location of ACa resistance in relation to known markers. Segregation analysis of 180 single-seed-descent F₃ families showed that aca1 was linked to marker tt3. Marker tt3 is located on chromosome V of Arabidopsis thaliana. Segregation of tt3 and aca1 did not show a 9:3:3:1 ratio, suggesting that aca1 was closely linked to tt3, located 62.1 cM from the end of chromosome V. The transparent testa phenotype of KG3 was complemented by locus tt4 also located on this chromosome. To determine the basis of enhanced NaCl tolerance in KG3, F₃ families from a cross between KG3 and Columbia pubescent wild type were tested for NaCl resistance. Families showing optimal growth after release from salt stress were scored for NaCl tolerance. Segregation analysis indicated that the salt tolerance in KG3 was due to a single recessive gene mutation called salt addicted (sad1). The sad1 phenotype appeared to have required NaCl for optimal growth. Segregation analysis of aca1 and sad1 phenotype showed that they were not linked. Molecular mapping of aca-1 was done by using a number of RFLP markers selected from all five Arabidopsis thaliana chromosomes. This study indicated that aca1 was linked with markers m331 and m435, located at positions 73.4 cM and 80.2 cM, respectively, on chromosome V on the unified map of Arabidopsis thaliana. Thus, the map location of aca1 was found to lie within 62 to 67 centimorgans on chromosome V.
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Webster, P. S. "The ease of carbon-nitrogen bond fission in axetidine derivatives." Thesis, University of Huddersfield, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384650.

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Books on the topic "Azetidinone"

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Webster, Philip S. The ease of carbon-nitrogen bond fission in azetidine derivatives. Huddersfield: The Polytechnic, 1988.

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Investigation of Some Routes to Azetidine. Hassell Street Press, 2021.

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Webster, Philip S. The ease of carbon-nitrogen bond fission in azetidine derivatives. Polytechnic, Huddersfield, 1988.

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Book chapters on the topic "Azetidinone"

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Hirota, E., K. Kuchitsu, T. Steimle, J. Vogt, and N. Vogt. "31 C3H5NO 2-Azetidinone." In Molecules Containing Three or Four Carbon Atoms and Molecules Containing Five or More Carbon Atoms, 61. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-41504-3_32.

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Demaison, J. "307 C3H5NO 2-Azetidinone." In Asymmetric Top Molecules. Part 2, 108–9. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-10400-8_55.

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Prieto, A., J. I. Iribarren, S. Muñoz-Guerra, C. Bui, and H. Sekiguchi. "Structural Study on the Chiral Nylon-3, Poly(3,3-Ethyl Phenyl-2-Azetidinone)." In Crystallization of Polymers, 613–18. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1950-4_65.

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Demaison, J. "352 C3H7N Azetidine." In Asymmetric Top Molecules. Part 2, 192–94. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-10400-8_100.

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Yoda, Hidemi, Masaki Takahashi, and Tetsuya Sengoku. "Azetidine and Its Derivatives." In Heterocycles in Natural Product Synthesis, 41–61. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634880.ch2.

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Alcaide, Benito, Pedro Almendros, and Amparo Luna. "The Chemistry of 2-Azetidinones (β-Lactams)." In Modern Heterocyclic Chemistry, 2117–73. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527637737.ch24.

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Faigl, F., E. Kovács, G. Turczel, L. Hegedűs, A. Thurner, F. Farkas, and Á. Szöllősy. "Novel Methods for the Stereoselective Synthesis of Oxetane, Azetidine and Pyrrolidine Derivatives." In IFMBE Proceedings, 1366–69. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-23508-5_352.

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Yunes, J. S., P. Rowell, and N. W. Kerby. "Growth and Amino Acid Liberation by a Mutant Strain of Anabaena Variabilis Resistant to the Amino Acid Analogue Azetidine 2-Carboxylic Acid." In Nitrogen Fixation, 519–20. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3486-6_105.

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Boyd, G. V. "From an Azetidinone." In Five-Membered Hetarenes with One Chalcogen and One Additional Heteroatom, 1. Georg Thieme Verlag KG, 2002. http://dx.doi.org/10.1055/sos-sd-011-00621.

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Pramod, N., C. Bharath Kumar, P. Sri Lekha, and B. Mayuri. "Role of Pyridine Containing Azetidinone Derivatives as Privileged Scaffolds in Anti Tubercular Agents." In Technological Innovation in Pharmaceutical Research Vol. 11, 105–12. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/tipr/v11/3921f.

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Conference papers on the topic "Azetidinone"

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Hassan, Hammed H. A. M., and Raafat Soliman. "DI-ALPHA-N-(2'-AZETIDINONE)-2-AZETIDINONE HAVING N-SULFONAMIDE DRUGS SIDE CHAIN: A NEW TYPE OF BETA-LACTAMS CONTAINING CARBOHYDRATES." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.636.

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Sankar, P. Siva, K. Divya, G. Dinneswara Reddy, V. Padmavathi, and Grigory V. Zyryanov. "Synthesis, characterization and antimicrobial activity of azetidinone and thiazolidinone derivatives." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON AUTOMOTIVE INNOVATION GREEN ENERGY VEHICLE: AIGEV 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5087379.

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Luna, Amparo, Pedro Almendros, and Benito Alcaide. "Diastereoselective direct aldol reaction and subsequent cyclization of 2-azetidinone-tethered azides for the preparation of a 4-hydroxypipecolic acid analogue." In The 13th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00174.

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Supe, Linda. "Synthesis of Azetidine-Based Beta-Amino Alcohols." In ECMC 2022. Basel Switzerland: MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13471.

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Yue, Peibin, Francisco Lopez-Tapia, Wenzhen Fu, Christine Brotherton-Pleiss, Marcus Tius, and James Turkson. "Abstract 4792: Azetidine functionalized small-molecules potently inhibit STAT3 signaling and block tumor growth in human breast cancer xenografts." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-4792.

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Yue, Peibin, Francisco Lopez-Tapia, Wenzhen Fu, Christine Brotherton-Pleiss, Marcus Tius, and James Turkson. "Abstract 4792: Azetidine functionalized small-molecules potently inhibit STAT3 signaling and block tumor growth in human breast cancer xenografts." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-4792.

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Yue, Peibin, Francisco Lopez-Tapia, Yinsong Zhu, Christine Brotherton-Pleiss, Wenzhen Fu, Felix Alonso-Valenteen, Simoun Mikhael, Lali Medina-Kauwe, Marcus Tius, and James Turkson. "Abstract 1230: High-affinity azetidine-based small-molecules as a new class of direct inhibitors of STAT3 activity and breast cancer phenotype." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1230.

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