Relevant bibliographies by topics / AuNC

Academic literature on the topic 'AuNC'

Author: Grafiati
Published: 7 July 2024

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Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Journal articles on the topic "AuNC":

1

Song, Lina, Shuai Ren, Yali Yue, Ying Tian, and Zhongqiu Wang. "A Gold Nanocage Probe Targeting Survivin for the Diagnosis of Pancreatic Cancer." Pharmaceutics 15, no. 5 (May 19, 2023): 1547. http://dx.doi.org/10.3390/pharmaceutics15051547.

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In this paper, Au nanocages (AuNCs) loaded with the MRI contrast agent gadolinium (Gd) and capped with the tumor-targeting gene survivin (Sur–AuNC•Gd–Cy7 nanoprobes) were designed and applied as a targeted imaging agent for pancreatic cancer. With its capacity to transport fluorescent dyes and MR imaging agents, the gold cage is an outstanding platform. Furthermore, it has the potential to transport different drugs in the future, making it a unique carrier platform. The utilization of Sur–AuNC•Gd–Cy7 nanoprobes has proven to be an effective means of targeting and localizing survivin-positive BxPC-3 cells within their cytoplasm. By targeting survivin, an antiapoptotic gene, the Sur–AuNC•Gd–Cy7 nanoprobe was able to induce pro-apoptotic effects in BxPC-3 pancreatic cancer cells. The biocompatibility of AuNCs•Gd, AuNCs•Gd–Cy7 nanoparticles, and Sur–AuNC•Gd–Cy7 nanoprobes is evaluated through the hemolysis rate assay. The stability of AuNCs•Gd, AuNCs•Gd–Cy7 nanoparticles, and Sur–AuNC•Gd–Cy7 nanoprobes was evaluated by determining their hydrodynamic dimensions following storage in different pH solutions for a corresponding duration. Excellent biocompatibility and stability of the Sur–AuNC•Gd–Cy7 nanoprobes will facilitate their further utilization in vivo and in vitro. The surface-bound survivin plays a role in facilitating the Sur–AuNC•Gd–Cy7 nanoprobes’ ability to locate the BxPC-3 tumor. The probe was modified to incorporate Gd and Cy7, thereby enabling the simultaneous utilization of magnetic resonance imaging (MRI) and fluorescence imaging (FI) techniques. In vivo, the Sur–AuNC•Gd–Cy7 nanoprobes were found to effectively target and localize survivin-positive BxPC-3 tumors through the use of MRI and FI. After being injected via the caudal vein, the Sur–AuNC•Gd–Cy7 nanoprobes were found to accumulate effectively in an in situ pancreatic cancer model within 24 h. Furthermore, these nanoprobes were observed to be eliminated from the body through the kidneys within 72 h after a single injection. This characteristic is crucial for a diagnostic agent. Based on the aforementioned outcomes, the Sur–AuNC•Gd–Cy7 nanoprobes have significant potential advantages for the theranostic treatment of pancreatic cancer. This nanoprobe possesses distinctive characteristics, such as advanced imaging abilities and specific drug delivery, which offer the possibility of enhancing the precision of diagnosis and efficacy of treatment for this destructive illness.
2

Wei, Ming, Ye Tian, Lijun Wang, Yuankai Hong, Dan Luo, and Yinlin Sha. "The Emission Mechanism of Gold Nanoclusters Capped with 11-Mercaptoundecanoic Acid, and the Detection of Methanol in Adulterated Wine Model." Materials 14, no. 21 (October 23, 2021): 6342. http://dx.doi.org/10.3390/ma14216342.

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The absorption and emission mechanisms of gold nanoclusters (AuNCs) have yet to be understood. In this article, 11-Mercaptoundecanoic acid (MUA) capped AuNCs (AuNC@MUA) were synthesized using the chemical etching method. Compared with MUA, AuNC@MUA had three obvious absorption peaks at 280 nm, 360 nm, and 390 nm; its photoluminescence excitation (PLE) peak and photoluminescence (PL) peak were located at 285 nm and 600 nm, respectively. The AuNC@MUA was hardly emissive when 360 nm and 390 nm were chosen as excitation wavelengths. The extremely large stokes-shift (>300 nm), and the mismatch between the excitation peaks and absorption peaks of AuNC@MUA, make it a particularly suitable model for studying the emission mechanism. When the ligands were partially removed by a small amount of sodium hypochlorite (NaClO) solution, the absorption peak showed a remarkable rise at 288 nm and declines at 360 nm and 390 nm. These experimental results illustrated that the absorption peak at 288 nm was mainly from metal-to-metal charge transfer (MMCT), while the absorption peaks at 360 nm and 390 nm were mainly from ligand-to-metal charge transfer (LMCT). The PLE peak coincided with the former absorption peak, which implied that the emission of the AuNC@MUA was originally from MMCT. It was also interesting that the emission mechanism could be switched to LMCT from MMCT by decreasing the size of the nanoclusters using 16-mercaptohexadecanoic acid (MHA), which possesses a stronger etching ability. Moreover, due to the different PL intensities of AuNC@MUA in methanol, ethanol, and water, it has been successfully applied in detecting methanol in adulterated wine models (methanol-ethanol-water mixtures).
3

Broekgaarden, Mans, Anne-Laure Bulin, Estelle Porret, Benjamin Musnier, Benoit Chovelon, Corinne Ravelet, Lucie Sancey, et al. "Surface functionalization of gold nanoclusters with arginine: a trade-off between microtumor uptake and radiotherapy enhancement." Nanoscale 12, no. 13 (2020): 6959–63. http://dx.doi.org/10.1039/d0nr01138j.

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Gold nanoclusters (AuNC) have strong potential for cancer imaging and therapy. We demonstrate that optimizing the surface chemistry of AuNCs for increased tumor uptake can significantly affect its potential to augment radiotherapy outcomes.
4

Jung, Seunghyun, Nathaniel Harris, Isabelle I. Niyonshuti, Samir V. Jenkins, Abdallah M. Hayar, Fumiya Watanabe, Azemat Jamshidi-Parsian, Jingyi Chen, Michael J. Borrelli, and Robert J. Griffin. "Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation." Nanomaterials 11, no. 5 (May 4, 2021): 1216. http://dx.doi.org/10.3390/nano11051216.

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Strategies to increase the proportion of neural stem cells that differentiate into neurons are vital for therapy of neurodegenerative disorders. In vitro, the extracellular matrix composition and topography have been found to be important factors in stem cell differentiation. We have developed a novel artificial extracellular matrix (aECM) formed by attaching gold nanocages (AuNCs) to glass coverslips. After culturing rat neural stem cells (rNSCs) on these gold nanocage-coated surfaces (AuNC-aECMs), we observed that 44.6% of rNSCs differentiated into neurons compared to only 27.9% for cells grown on laminin-coated glass coverslips. We applied laser irradiation to the AuNC-aECMs to introduce precise amounts of photothermally induced heat shock in cells. Our results showed that laser-induced thermal stimulation of AuNC-aECMs further enhanced neuronal differentiation (56%) depending on the laser intensity used. Response to these photothermal effects increased the expression of heat shock protein 27, 70, and 90α in rNSCs. Analysis of dendritic complexity showed that this thermal stimulation promoted neuronal maturation by increasing dendrite length as thermal dose was increased. In addition, we found that cells growing on AuNC-aECMs post laser irradiation exhibited action potentials and increased the expression of voltage-gated Na+ channels compared to laminin-coated glass coverslips. These results indicate that the photothermal response induced in cells growing on AuNC-aECMs can be used to produce large quantities of functional neurons, with improved electrochemical properties, that can potentially be transplanted into a damaged central nervous system to provide replacement neurons and restore lost function.
5

Russell, B. A., P. A. Mulheran, D. J. S. Birch, and Y. Chen. "Probing the Sudlow binding site with warfarin: how does gold nanocluster growth alter human serum albumin?" Physical Chemistry Chemical Physics 18, no. 33 (2016): 22874–78. http://dx.doi.org/10.1039/c6cp03428d.

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Gold Nanoclusters (AuNCs) synthesised using Human Serum Albumin (HSA) as a stable scaffold are shown to modify the major drug binding site, Sudlow site I. Upon AuNC nucleation within HSA, warfarin was observed to no longer bind to Sudlow I, remaining free in solution.
6

Arivazhagan, Mani, Palanisamy Kannan, and Govindhan Maduraiveeran. "Gold Nanoclusters Dispersed on Gold Dendrite-Based Carbon Fibre Microelectrodes for the Sensitive Detection of Nitric Oxide in Human Serum." Biosensors 12, no. 12 (December 5, 2022): 1128. http://dx.doi.org/10.3390/bios12121128.

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Herein, gold nanoclusters (Au NC) dispersed on gold dendrite (Au DS)-based flexible carbon fibre (AuNC@AuDS|CF) microelectrodes are developed using a one-step electrochemical approach. The as-fabricated AuNC@AuDS|CF microelectrodes work as the prospective electrode materials for the sensitive detection of nitric oxide (NO) in a 0.1 M phosphate buffer (PB) solution. Carbon microfibre acts as an efficient matrix for the direct growth of AuNC@AuDS without any binder/extra reductant. The AuNC@AuDS|CF microelectrodes exhibit outstanding electrocatalytic activity towards NO oxidation, which is ascribed to their large electrochemical active surface area (ECSA), high electrical conductivity, and high dispersion of Au nanoclusters. As a result, the AuNC@AuDS|CF microelectrodes attain a rapid response time (3 s), a low limit of detection (LOD) (0.11 nM), high sensitivity (66.32 µA µM cm−2), a wide linear range (2 nM–7.7 µM), long-term stability, good reproducibility, and a strong anti-interference capability. Moreover, the present microsensor successfully tested for the discriminating detection of NO in real human serum samples, revealing its potential practicability.
7

Sun, Jing, Wenwen Fang, Afroza Akter Liza, Rui Gao, Junlong Song, Jiaqi Guo, and Orlando J. Rojas. "Photoluminescent Nanocellulosic Film for Selective Hg2+ Ion Detection." Polymers 16, no. 11 (June 3, 2024): 1583. http://dx.doi.org/10.3390/polym16111583.

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We developed a highly sensitive solid-state sensor for mercury detection by stabilizing red-sub-nanometric fluorescent gold nanoclusters (AuNC, 0.9 ± 0.1 nm diameter) with bovine serum albumin in a matrix composed of cellulose nanofibrils (CNF) (BSA-AuNC/CNF). The main morphological and optical features of the system were investigated via atomic force/transmission electron microscopy and UV-Vis/fluorescence spectroscopy. The hybrid film (off-white and highly transparent) showed strong photoluminescene under UV irradiation. The latter is assigned to the AuNC, which also increase the ductility of the emitting film, which was demonstrated for high sensitivity Hg2+ detection. When used as a sensor system, following AuNC printing on CNF hybrid films, a limit of detection <10 nM was confirmed. What is more, nanocellulose films have a high pore structure and selective separation properties, showcasing a wide range of potential applications in many fields such as water treatment and oil–water separation.
8

Poletti, Annamaria, Giulio Fracasso, Giamaica Conti, Roberto Pilot, and Vincenzo Amendola. "Laser generated gold nanocorals with broadband plasmon absorption for photothermal applications." Nanoscale 7, no. 32 (2015): 13702–14. http://dx.doi.org/10.1039/c5nr03442f.

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Gold nanocorals (AuNC) are obtained by a “green” method consisting of laser irradiation, followed by anisotropic self-assembly without templating agents. The AuNC dispersion has broadband plasmon absorption from the visible to near infrared region, unitary light-to-heat conversion efficiency, versatile surface chemistry and biocompatibility.
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Fabijanić, Ivana, Marta Jurković, Daniela Jakšić, and Ivo Piantanida. "Photoluminescent Gold/BSA Nanoclusters (AuNC@BSA) as Sensors for Red-Fluorescence Detection of Mycotoxins." Materials 15, no. 23 (November 27, 2022): 8448. http://dx.doi.org/10.3390/ma15238448.

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The BSA-encapsulated gold nanoclusters (AuNC@BSA) have drawn considerable interest and demonstrated applications as biological sensors. In this study, we demonstrated that the red-emitting AuNC@BSA prepared using a modified procedure fully retained the binding of standard BSA-ligands (small molecule drugs), significantly improving fluorescence detection in some cases due to the red-emission property. Further, we showed that AuNC@BSA efficiently bind a series of aflatoxin-related mycotoxins as well as the aliphatic mycotoxin FB1, reporting interactions in the nanomolar range by instantaneous emission change at 680 nm. Such red emission detection is advantageous over current detection strategies for the same mycotoxins, based on complex mass spectrometry procedures or, eventually (upon chemical modification of the mycotoxin), by fluorescence detection in the UV range (<400 nm). The later technique yields fluorescence strongly overlapping with the intrinsic absorption and emission of biorelevant mixtures in which mycotoxins appear. Thus, here we present a new approach using the AuNC@BSA red fluorescence reporter for mycotoxins as a fast, cheap, and simple detection technique that offers significant advantages over currently available methods.
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Paramanik, Bipattaran, Amrita Kundu, Krishnananda Chattopadhyay, and Amitava Patra. "Study of binding interactions between MPT63 protein and Au nanocluster." RSC Adv. 4, no. 66 (2014): 35059–66. http://dx.doi.org/10.1039/c4ra03708a.

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Journal articles Dissertations / Theses Books

Dissertations / Theses on the topic "AuNC":

1

Diriwari, Peremobowei Iyanu. "Resonance Energy Transfer within and to optical Nanoparticles for Bioimaging and Biosensing Applications." Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMR007.

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La biosensibilité et la bio-imagerie basées sur la fluorescence jouent des rôles cruciaux dans le développement d'outils de diagnostic rapides et hautement sensibles pour la détection précoce des maladies et la mise en oeuvre d’une médecine de terrain efficace. Cependant, ces techniques nécessitent une certaine optimisation pour obtenir des images haute résolution et des limites de détection très faibles. Cette thèse se concentre sur l'utilisation de nanoparticules optiques et de mécanismes de transfert d'énergie résonant pour des applications avancées en bio-imagerie et en détection de biomolécules. Je présente les analyses spectroscopiques de nanoclusters d'or luminescents encapsulés dans des polymères (AuNC-NPs) adaptés à la bio-imagerie dans la région infrarouge à ondes courtes (SWIR). L’étude des deux temps de vie de luminescence communément décrits dans les AuNCs m’a permis d’obtenir de nouveaux éléments pour comprendre l’origine de leur luminescence. J’ai découvert que ces temps de vie ne sont pas sensibles de la même manière à l’extinction par homoFRET ce qui suggèrent qu’ils sont causés par des mécanismes différents et des parties distincts de ces nano-objets telles que leur surface constituée de thiolate d’or et leur coeur. J'ai également caractérisé une nouvelle famille de complexes de terbium de CoraFluor (CRF) avec plusieurs méthodes spectroscopiques. J'ai découvert qu'ils sont un donneur de transfert d'énergie applicable en tant que sonde FRET et NSET. J'ai atteint des limites sub-nanomolaires pour la détection de points quantiques et j'ai appliqué ce système pour détecter le récepteur du facteur de croissance épidermique (EGFR). Cette thèse décrit le rôle pivot des mécanismes RET, en particulier du FRET, dans l'avancement des technologies de biosensibilité et de bio-imagerie basées sur la fluorescence. Grâce à des conceptions innovantes de nanoparticules et à une utilisation stratégique des complexes Corafluor Tb, l'étude vise à améliorer la résolution de la bio-imagerie dans la région SWIR et à améliorer la sensibilité, la spécificité et l'applicabilité des outils de diagnostic, contribuant ainsi à l'avancement de la médecine de précision et de la gestion des maladies
Fluorescence-based biosensing and bioimaging play crucial roles in developing rapid and highly sensitive diagnostic tools for early detection of diseases and effective point-of-care medicine. However, these techniques require some optimisation to attain high-resolution images and very low detection limits. This thesis focuses on utilising luminescent nanoparticles and Resonance energy transfer mechanisms for advanced bioimaging and biosensing applications. I present the spectroscopic analyses of bright polymer encapsulated gold nanoclusters (AuNC-NPs) suitable for bioimaging in the shortwave infrared (SWIR) region. My study of the two photoluminescence lifetimes commonly measured in AuNCs allowed me to gather new insight to understand the origin of their luminescence. I discovered that each of these lifetimes are not sensitive in the same way to homo FRET suggesting that they originate from distinct mechanisms and distinct parts of the AuNCs such as the gold thiolate surface or the core of the nano-object. I have also characterised a new family of terbium complexes from CoraFluor (CRF) with several spectroscopic methods. I have found that they are a suitable energy transfer donor for FRET and NSET biosensing applications with gold nanoparticles. I attained sub-nanomolar limits of detection of quantum dots and have applied the system to detect the epidermal growth factor receptor (EGFR). This thesis describes the pivotal role of RET mechanisms, particularly FRET, in advancing fluorescence-based biosensing and bioimaging technologies. With innovative nanoparticle designs and strategic use of Corafluor Tb complexes, the study aims to enhance the bioimaging resolution in the SWIR region and improve diagnostic tool sensitivity, specificity and applicability, contributing to advancing precision medicine and disease management
2

Karabudak, Engin. "Development of MWL-AUC / CCD-C-AUC / SLS-AUC detectors for the analytical ultracentrifuge." Phd thesis, Universität Potsdam, 2009. http://opus.kobv.de/ubp/volltexte/2009/3992/.

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Analytical ultracentrifugation (AUC) has made an important contribution to polymer and particle characterization since its invention by Svedberg (Svedberg and Nichols 1923; Svedberg and Pederson 1940) in 1923. In 1926, Svedberg won the Nobel price for his scientific work on disperse systems including work with AUC. The first important discovery performed with AUC was to show the existence of macromolecules. Since that time AUC has become an important tool to study polymers in biophysics and biochemistry. AUC is an absolute technique that does not need any standard. Molar masses between 200 and 1014 g/mol and particle size between 1 and 5000 nm can be detected by AUC. Sample can be fractionated into its components due to its molar mass, particle size, structure or density without any stationary phase requirement as it is the case in chromatographic techniques. This very property of AUC earns it an important status in the analysis of polymers and particles. The distribution of molar mass, particle sizes and densities can be measured with the fractionation. Different types of experiments can give complementary physicochemical parameters. For example, sedimentation equilibrium experiments can lead to the study of pure thermodynamics. For complex mixtures, AUC is the main method that can analyze the system. Interactions between molecules can be studied at different concentrations without destroying the chemical equilibrium (Kim et al. 1977). Biologically relevant weak interactions can also be monitored (K ≈ 10-100 M-1). An analytical ultracentrifuge experiment can yield the following information: • Molecular weight of the sample • Number of the components in the sample if the sample is not a single component • Homogeneity of the sample • Molecular weight distribution if the sample is not a single component • Size and shape of macromolecules & particles • Aggregation & interaction of macromolecules • Conformational changes of macromolecules • Sedimentation coefficient and density distribution Such an extremely wide application area of AUC allows the investigation of all samples consisting of a solvent and a dispersed or dissolved substance including gels, micro gels, dispersions, emulsions and solutions. Another fact is that solvent or pH limitation does not exist for this method. A lot of new application areas are still flourishing, although the technique is 80 years old. In 1970s, 1500 AUC were operational throughout the world. At those times, due to the limitation in detection technologies, experimental results were obtained with photographic records. As time passed, faster techniques such as size exclusion chromatography (SEC), light scattering (LS) or SDS-gel electrophoresis occupied the same research fields with AUC. Due to these relatively new techniques, AUC began to loose its importance. In the 1980s, only a few AUC were in use throughout the world. In the beginning of the 1990s a modern AUC -the Optima XL-A - was released by Beckman Instruments (Giebeler 1992). The Optima XL-A was equipped with a modern computerized scanning absorption detector. The addition of Rayleigh Interference Optics is introduced which is called XL-I AUC. Furthermore, major development in computers made the analysis easier with the help of new analysis software. Today, about 400 XL-I AUC exist worldwide. It is usually applied in the industry of pharmacy, biopharmacy and polymer companies as well as in academic research fields such as biochemistry, biophysics, molecular biology and material science. About 350 core scientific publications which use analytical ultracentrifugation are published every year (source: SciFinder 2008 ) with an increasing number of references (436 reference in 2008). A tremendous progress has been made in method and analysis software after digitalization of experimental data with the release of XL-I. In comparison to the previous decade, data analysis became more efficient and reliable. Today, AUC labs can routinely use sophisticated data analysis methods for determination of sedimentation coefficient distributions (Demeler and van Holde 2004; Schuck 2000; Stafford 1992), molar mass distributions (Brookes and Demeler 2008; Brookes et al. 2006; Brown and Schuck 2006), interaction constants (Cao and Demeler 2008; Schuck 1998; Stafford and Sherwood 2004), particle size distributions with Angstrom resolution (Cölfen and Pauck 1997) and the simulations determination of size and shape distributions from sedimentation velocity experiments (Brookes and Demeler 2005; Brookes et al. 2006). These methods are also available in powerful software packages that combines various methods, such as, Ultrascan (Demeler 2005), Sedift/Sedphat (Schuck 1998; Vistica et al. 2004) and Sedanal (Stafford and Sherwood 2004). All these powerful packages are free of charge. Furthermore, Ultrascans source code is licensed under the GNU Public License (http://www.gnu.org/copyleft/gpl.html). Thus, Ultrascan can be further improved by any research group. Workshops are organized to support these software packages. Despite of the tremendous developments in data analysis, hardware for the system has not developed much. Although there are various user developed detectors in research laboratories, they are not commercially available. Since 1992, only one new optical system called “the fluorescence optics” (Schmidt and Reisner, 1992, MacGregor et al. 2004, MacGregor, 2006, Laue and Kroe, in press) has been commercialized. However, except that, there has been no commercially available improvement in the optical system. The interesting fact about the current hardware of the XL-I is that it is 20 years old, although there has been an enormous development in microelectronics, software and in optical systems in the last 20 years, which could be utilized for improved detectors. As examples of user developed detector, Bhattacharyya (Bhattacharyya 2006) described a Multiwavelength-Analytical Ultracentrifuge (MWL-AUC), a Raman detector and a small angle laser light scattering detector in his PhD thesis. MWL-AUC became operational, but a very high noise level prevented to work with real samples. Tests with the Raman detector were not successful due to the low light intensity and thus high integration time is required. The small angle laser light scattering detector could only detect latex particles but failed to detect smaller particles and molecules due to low sensitivity of the detector (a photodiode was used as detector). The primary motivation of this work is to construct a detector which can measure new physico-chemical properties with AUC with a nicely fractionated sample in the cell. The final goal is to obtain a multiwavelength detector for the AUC that measures complementary quantities. Instrument development is an option for a scientist only when there is a huge potential benefit but there is no available commercial enterprise developing appropriate equipment, or if there is not enough financial support to buy it. The first case was our motivation for developing detectors for AUC. Our aim is to use today’s technological advances in microelectronics, programming, mechanics in order to develop new detectors for AUC and improve the existing MWL detector to routine operation mode. The project has multiple aspects which can be listed as mechanical, electronical, optical, software, hardware, chemical, industrial and biological. Hence, by its nature it is a multidisciplinary project. Again by its nature it contains the structural problem of its kind; the problem of determining the exact discipline to follow at each new step. It comprises the risk of becoming lost in some direction. Having that fact in mind, we have chosen the simplest possible solution to any optical, mechanical, electronic, software or hardware problem we have encountered and we have always tried to see the overall picture. In this research, we have designed CCD-C-AUC (CCD Camera UV/Vis absorption detector for AUC) and SLS-AUC (Static Light Scattering detector for AUC) and tested them. One of the SLS-AUC designs produced successful test results, but the design could not be brought to the operational stage. However, the operational state Multiwavelength Analytical Ultracentrifuge (MWL-AUC) AUC has been developed which is an important detector in the fields of chemistry, biology and industry. In this thesis, the operational state Multiwavelength Analytical Ultracentrifuge (MWL-AUC) AUC is to be introduced. Consequently, three different applications of MWL-AUC to the aforementioned disciplines shall be presented. First of all, application of MWL-AUC to a biological system which is a mixture of proteins lgG, aldolase and BSA is presented. An application of MWL-AUC to a mass-produced industrial sample (β-carotene gelatin composite particles) which is manufactured by BASF AG, is presented. Finally, it is shown how MWL-AUC will impact on nano-particle science by investigating the quantum size effect of CdTe and its growth mechanism. In this thesis, mainly the relation between new technological developments and detector development for AUC is investigated. Pioneering results are obtained that indicate the possible direction to be followed for the future of AUC. As an example, each MWL-AUC data contains thousands of wavelengths. MWL-AUC data also contains spectral information at each radial point. Data can be separated to its single wavelength files and can be analyzed classically with existing software packages. All the existing software packages including Ultrascan, Sedfit, Sedanal can analyze only single wavelength data, so new extraordinary software developments are needed. As a first attempt, Emre Brookes and Borries Demeler have developed mutliwavelength module in order to analyze the MWL-AUC data. This module analyzes each wavelength separately and independently. We appreciate Emre Brookes and Borries Demeler for their important contribution to the development of the software. Unfortunately, this module requires huge amount of computer power and does not take into account the spectral information during the analysis. New software algorithms are needed which take into account the spectral information and analyze all wavelengths accordingly. We would like also invite the programmers of Ultrascan, Sedfit, Sedanal and the other programs, to develop new algorithms in this direction.
Die analytische Chemie versucht die chemische Zusammensetzung, chemische und physikalische Eigenschaften von biologischen oder künstlichen Materialien zu bestimmen. Mit der Entwicklung deren Methoden können genauere Informationen über die Umweltverschmutzung, das Ozonloch, Proteinfunktionen und Wechselwirkungen im menschlichen Körper erlangt werden. Es sind eine Vielzahl von analytischen Techniken vorhanden, die durch Verbesserungen in der Mikroelektronik, Mechanik, Informatik und Nanotechnologie einer markanten Entwicklung unterworfen wurden. In dieser Arbeit wurde versucht die Detektionskapazität der analytischen Ultrazentrifuge zu erhöhen. Die analytische Ultrazentrifuge (AUZ) ist eine gut bekannte, sehr leistungsstarke Trennungsmethode. AUZ benutzt die Zentrifugalkraft zum Trennen von Stoffen. Die Probe kann für die Messung gelöst oder in einer Flüssigkeit dispergiert werden. Makromoleküle, Proteine und kolloidale Systeme in Lösung können in einer AUZ Zelle zwischen 1000-60000 Rotationen pro Minute zentrifugiert werden, wie beispielsweise in der kommerziellen Beckmann AUZ. Die Rotationsbeschleunigung entspricht 73-262mal der Erdschwerebeschleunigung (= 9.81 m s-2) für eine radiale Position von 6.5 Zentimeter. Diese Kraft ist der Schlüsselfaktor für die Fähigkeit der AUZ sogar kleine Moleküle und Ionen zu trennen. Die Experimente wurden bei kontrollierter Rotationsgeschwindigkeit und Temperatur ausgeführt. Drei verschiedene, neue Detektoren wurden im Rahmen dieser Arbeit konstruiert und getestet. Diese Detektoren haben die analytischen Informationen sehr verbessert. Dies wurde für Proteine, halbleitende Nanopartikel sowie auch für industrielle Produkte gezeigt.
3

Schenström, Karl. "Biofunctionalization of a Fiber Optics-Based LSPR Sensor." Thesis, Linköpings universitet, Molekylär fysik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-125726.

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When exposed to light, metal nanoparticles exhibit a phenomenon known as LSPR, Localized Surface Plasmon Resonance. The wavelengths at which LSPR occurs is very dependent on the refractive index of the surrounding medium. Binding of biomolecules to the surface of gold nanoparticles result in a change in the refractive index that can be detected spectrophotometrically by monitoring the LSPR peak shift. When functionalized with the corresponding ligand(s), gold nanoparticles can be utilized in biosensors to detect the presence and concentration of a predetermined analyte. However, the system must exhibit high specificity and give rise to a detectable shift for analytes in the desired concentration range to be of commercial interest. The aim of the diploma project was to investigate and optimize the biofunctionalization and performance of a fiber optics based LSPR biosensor.  Three ligand systems were investigated for detection of antibodies (IgG), insulin and avidin. Binding of the analyte to the ligand caused a shift of a few nanometers when using spherical gold nanoparticles. The shifts were significantly larger when using gold nanorods. When using the IgG and insulin ligands, only minor unspecific binding was observed. The setup thus shows great potential for use in a wide range of sensing applications.
4

McCloughan, Troy Michael. "Burying aunt Billie and other stories." Diss., Click here for available full-text of this thesis, 2006. http://library.wichita.edu/digitallibrary/etd/2006/t078.pdf.

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5

Pine, Lila. "My Aunt Lila, a mad documentary." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0016/MQ59195.pdf.

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6

Berry, Mary Louise Morman Mark T. "Communication in the aunt/adult niece dyad." Waco, Tex. : Baylor University, 2007. http://hdl.handle.net/2104/5037.

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Koitmäe, Aune [Verfasser]. "Hybrid Neural Networks on Semiconductor Microtube Arrays / Aune Koitmäe." München : Verlag Dr. Hut, 2016. http://d-nb.info/1103872745/34.

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Manring, M. M. "Merchandising the mammy : the strange career of Aunt Jermina /." free to MU campus, to others for purchase, 1996. http://wwwlib.umi.com/cr/mo/fullcit?p9821353.

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Cardoso, Laylla Donata. "A systemic functional approach to experiential meaning construal in agony aunt columns." Florianópolis, SC, 2007. http://repositorio.ufsc.br/xmlui/handle/123456789/90111.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras/Inglês e Literatura Correspondente.
Made available in DSpace on 2012-10-23T06:15:37Z (GMT). No. of bitstreams: 1 238448.pdf: 881628 bytes, checksum: 355ad2c765eed1b2e6ff47b7beaab256 (MD5)
Nos dias atuais, há uma crescente necessidade de socializar problemas pessoais e, notavelmente, as revistas femininas são um bom veículo para o compartilhamento de experiências. Nesta dissertação, investigo um gênero textual específico em revistas femininas, as colunas de aconselhamento. A função principal dessas colunas é responder e aconselhar leitoras sobre questões pessoais, normalmente relacionadas a problemas conjugais envolvendo sexo e amor, assim como relacionamento entre amigos. Este estudo propõe uma investigação lingüística de duas colunas de aconselhamento publicadas na revista Glamour. O objetivo principal é mostrar como as experiências são representadas nas cartas das leitoras e também nas cartas de aconselhamento. Para esse fim, em uma macro aborgadem, a análise deste gênero textual revela a estrutura esquemática das cartas sob consideração. E, em uma micro abordagem, este estudo examina a representação de experiências realizadas pelas escolhas de transitividade. O arcabouço analítico aplicado a esta pesquisa baseia-se na teoria sistêmico-funcional, principalmente nos estudos de Halliday (1985, 1994) e Halliday & Matthiessen (2004). Os resultados do presente trabalho indicam que: 1) as colunas de aconselhamento publicadas na revista Glamour podem ser consideradas um gênero textual híbrido, no qual as cartas das leitoras apresentam características narrativas, enquanto as cartas de aconselhamento apresentam estrutura exortativa; 2) a análise da transitividade revela que: (i) até mesmo em uma dimensão profissional, as experiências femininas estão relacionadas a emoções e relacionamentos pessoais; (ii) os processos materiais, relacionais e mentais aparecem em maior número, indicando que as experiências são construídas geralmente por representações de ações, relações de atribuição/identidade e compartilhamento de sentimentos/pensamentos; (iii) esses processos associam as experiências femininas aos contextos privado e profissional, à idealização de soluções para os problemas expostos, e à ações abstratas; (iv) as leitoras se representam em papéis passivos, como "vítimas" socialmente oprimidas, visto que a conselheira é representada de maneira autoconfiante, como uma solucionadora de problemas. Os resultados desta pesquisa esperam contribuir para a conscientização dos leitores, estimulando-os a refletir sobre as práticas textuais vigentes, bem como fornecer ferramentas teórico-analíticas para que possam discutir e desvendar significados freqüentemente obscuros nos textos. In contemporary days, there seems to be a growing need to socialize personal problems, and notably, women's magazines appear to be a good vehicle for sharing experiences. In this thesis, I investigate a specific genre in women's magazines, the Agony Aunt Columns, also known as advice columns. The main function of Agony Aunt Columns is to answer readers' letters by providing pieces of advice on personal issues, normally related to love, sex, and relationships in general. The present study proposes a linguistic investigation of two Agony Aunt Columns, published on Glamour magazine. The main objective of this work is to show how experiential meanings are construed in both, advice-seeking and advice-giving letters. For that purpose, at a macro level, a genre analysis reveals the schematic structure of the letters under consideration. And, at a micro level, this study examines the representation of experiential meanings realized by the transitivity choices. The analytical framework applied to this research is based on Systemic Functional theory, mainly on the works of Halliday (1985, 1994) and Halliday & Matthiessen (2004). The results of this study indicate that: 1) Glamour Agony Aunt Columns may be considered an example of hybrid genre, in which advice-seeking letters present narrative features, while advice-giving letters resemble the structure of hortatory text-types; 2) the transitivity analysis of the two Agony Aunt Columns reveals that: (i) even in a workplace dimension, women's experiences are related to emotions and private affairs; (ii) material, relational and mental processes appear in a major number, indicating that women's experiences are construed mostly by representations of actions, relationships of being and sharing of feelings/thoughts; (iii) the processes associate women's experiences with identification in the two contexts (private and professional), idealization (the solutions for their problems), and with abstract and non-abstract actions; (iv) advice-seekers tend to represent themselves in passive roles, as "victims" socially oppressed, whereas the advice-giver is strongly represented as a reliable self-confident problem solver. The findings of this research hope to contribute to raise language awareness, stimulate readers to reflect on textual practices, as well as empowering them with theoretically-oriented analytical tools for discussing and unveiling often hidden textual meanings.
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Aune, Katherine Pearl. "Improving vocabulary instruction to increase student comprehension and science literacy." Montana State University, 2012. http://etd.lib.montana.edu/etd/2012/aune/AuneK0812.pdf.

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This project was designed to investigate whether spending more class time and instructor planning time on teaching vocabulary would lead to improvement of student learning, attitude toward scientific vocabulary, and science literacy skills. Throughout the treatment the students spent more time working with terms chosen for each unit. This included activities that encouraged analysis of word meaning and comparison and analysis of relationships between terms. Summative assessments showed improvement in student comprehension along with increased confidence in their ability to perform lesson objectives. Additionally, the attitude students had toward science vocabulary and science literacy skills were more positive. The students also improved in their writing skills and use of appropriate terminology when working in groups and on projects.
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Books on the topic "AuNC":

1

Quattlebaum, Mary. Aunt CeeCee, Aunt Belle, and Mama's surprise. New York: Doubleday Book for Young Readers, 1999.

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Hill, Pamela. Aunt Lucy. Bath: Chivers Press, 1999.

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Hyŏn, Ki-yŏng. Aunt Suni. Cheju-do: Kak, 2008.

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Wiechmann, Barbara. Aunt Leaf. Woodstock, Illinois: Dramatic Publishing, 2012.

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Pinkwater, Daniel Manus. Aunt Lulu. New York: Aladdin Books, 1991.

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Wilson, Richard. Aunt Fritzi. Polk City, Iowa (P.O. Box 445, Polk City 50226): C. Drumm Books, 1987.

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Kolyer, John. Caligula's aunt. Newport Beach, Calif: Sangreal Press, 1988.

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Kissoon, Freddie. Aunt Agatha. Alexandria, VA: Alexander Street Press, 2003.

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Jones, Diana Wynne. Aunt Maria. New York: Greenwillow Books, 1991.

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Hyŏn, Ki-yŏng. Aunt Suni. Cheju-do: Kak, 2008.

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Book chapters on the topic "AuNC":

1

Saxena, Mamta. "Aunt Care." In Encyclopedia of Evolutionary Psychological Science, 1–3. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-16999-6_2262-1.

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Graham, Robert, Heather Leach, Helen Newall, Julie Armstrong, and John Singleton. "Agony Aunt." In The Road to Somewhere, 269–78. London: Macmillan Education UK, 2014. http://dx.doi.org/10.1007/978-1-137-40608-8_31.

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Scherrmann, Jean-Michel, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, et al. "AUC." In Encyclopedia of Psychopharmacology, 182. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4071.

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Hilgers, R. D., N. Heussen, and S. Stanzel. "AUC." In Springer Reference Medizin, 230. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_326.

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Hilgers, R. D., N. Heussen, and S. Stanzel. "AUC." In Lexikon der Medizinischen Laboratoriumsdiagnostik, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_326-1.

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Kakas, Antonis C., David Cohn, Sanjoy Dasgupta, Andrew G. Barto, Gail A. Carpenter, Stephen Grossberg, Geoffrey I. Webb, et al. "AUC." In Encyclopedia of Machine Learning, 53. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-30164-8_44.

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Vu, Thi Hong Hanh, and Thanh Hai Truong. "Climate Change and Cities in the Mekong Delta, Vietnam." In AUC 2019, 3–17. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5608-1_1.

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Le, Phuoc Dinh, and Huyen Minh Do. "Urban Planning in Vietnam: Why Gender Matters." In AUC 2019, 123–36. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5608-1_10.

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Agarwal, Siddharth, Shabnam Verma, Kanupriya Kothiwal, Neeraj Verma, and Kailash Vishvakarma. "Slum Children-Youth Groups Demonstrate Zest, Collective Confidence and Tenacity to Improve Access to Education and Self-development Opportunities." In AUC 2019, 137–48. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5608-1_11.

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Dinh, Hai Dung, and Khoi Minh Le. "On the Use of Data Envelopment Analysis to Improve Performance Efficiency of Governmental Management in Big Cities." In AUC 2019, 149–57. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5608-1_12.

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Conference papers on the topic "AuNC":

1

Yoo, Su Woong, Hyoyoung Mun, Gyungseok Oh, Youngjae Ryu, Min-Gon Kim, and Euiheon Chung. "Light shift from ultraviolet to near infrared light: Cerenkov luminescence with gold nanocluster - near infrared (AuNc-NIR) conjugates." In SPIE BiOS, edited by Daniel L. Farkas, Dan V. Nicolau, and Robert C. Leif. SPIE, 2015. http://dx.doi.org/10.1117/12.2080898.

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Miller, Tim, and Paul Taylor. "Aunt Luisa." In ACM SIGGRAPH 2003 video review. New York, New York, USA: ACM Press, 2003. http://dx.doi.org/10.1145/1006114.1006132.

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Han, Peng, Shuo Shang, Aixin Sun, Peilin Zhao, Kai Zheng, and Panos Kalnis. "AUC-MF: Point of Interest Recommendation with AUC Maximization." In 2019 IEEE 35th International Conference on Data Engineering (ICDE). IEEE, 2019. http://dx.doi.org/10.1109/icde.2019.00141.

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Min, Geyong, Keqiu Li, Xiaolong Jin, and Ahmed Y. Al-Dubai. "Message from AUCN Symposium Chairs." In 2012 IEEE 11th International Conference on Trust, Security and Privacy in Computing and Communications (TrustCom). IEEE, 2012. http://dx.doi.org/10.1109/trustcom.2012.334.

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Flanagan, F., R. Bates, S. West, E. S. Katz, and K. Haver. "Is Respiratory Flutter an "Aunt Minnie"." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5359.

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Khalid, Majdi, Hamidreza Chitsaz, and Indrakshi Ray. "Proximal Stochastic AUC Maximization." In 2020 International Joint Conference on Neural Networks (IJCNN). IEEE, 2020. http://dx.doi.org/10.1109/ijcnn48605.2020.9206926.

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Christensen, Henrik I. "AUC robot camera head." In Aerospace Sensing, edited by Kevin W. Bowyer. SPIE, 1992. http://dx.doi.org/10.1117/12.58560.

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Graf, Mike, Ralf Küsters, and Daniel Rausch. "AUC: Accountable Universal Composability." In 2023 IEEE Symposium on Security and Privacy (SP). IEEE, 2023. http://dx.doi.org/10.1109/sp46215.2023.10179384.

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"Message from the AUCN 2015 Symposium Chair." In 2015 IEEE International Conference on Computer and Information Technology; Ubiquitous Computing and Communications; Dependable, Autonomic and Secure Computing; Pervasive Intelligence and Computing (CIT/IUCC/DASC/PICOM). IEEE, 2015. http://dx.doi.org/10.1109/cit/iucc/dasc/picom.2015.398.

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Roy, Shibdas, and Ian R. Petersen. "Robust H∞ coherent-classical estimation of linear quantum systems." In 2016 Australian Control Conference (AuCC). IEEE, 2016. http://dx.doi.org/10.1109/aucc.2016.7868220.

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Reports on the topic "AuNC":

1

Schrecengost, Robert A., Buchi Reddy Ganta, and Monica Soare. Advanced Ultrasupercritical (AUSC) Materials Thick-Walled Cycling Header Development for ComTest-AUSC. Office of Scientific and Technical Information (OSTI), March 2018. http://dx.doi.org/10.2172/1431234.

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Pschirer, James, Joshua Burgess, and Robert Schrecengost. Advanced Ultrasupercritical (AUSC) Tube Membrane Panel Development. Office of Scientific and Technical Information (OSTI), August 2017. http://dx.doi.org/10.2172/1375249.

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Huang, Roger. Burmese elections 2010: Moving beyond Aung San Suu Kyi. East Asia Forum, May 2010. http://dx.doi.org/10.59425/eabc.1273228876.

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Shultz, Travis, Eric Lewis, Drew O'Connell, Sydney Hughes, and Mark Woods. Development of Advanced Ultra-Supercritical (AUSC) Pulverized Coal (PC) Plants. Office of Scientific and Technical Information (OSTI), November 2022. http://dx.doi.org/10.2172/1968039.

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Staroselsky, Alexander, Michael Klecka, Anthony Ventura, Ranadip Acharya, Dmytro Voytovich, Anand Kulkarni, Jason Weissman, et al. Optimization of WAAM Process to Produce AUSC Components with Increased Service Life. Office of Scientific and Technical Information (OSTI), May 2022. http://dx.doi.org/10.2172/1871813.

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Wu, Jin Chu, Alvin F. Martin, and Raghu N. Kacker. Validation of two-sample bootstrap in ROC analysis on large dataset using AURC. Gaithersburg, MD: National Institute of Standards and Technology, 2010. http://dx.doi.org/10.6028/nist.ir.7733.

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Ahmed AlGarf, Yasmine. AUC Venture Lab: Encouraging an entrepreneurial culture to increase youth employment. Oxfam IBIS, August 2021. http://dx.doi.org/10.21201/2021.7888.

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The American University in Cairo Venture Lab (V-Lab) is the first university-based startup accelerator in Egypt. Oxfam’s Youth Participation and Employment (YPE) programme in Egypt partnered with V-Lab to support youth in entrepreneurship and business startups. V-Lab provides dynamic business support to entrepreneurs with innovative and scalable ideas. Its work has brought about change in Egypt’s culture and business environment. In this case study, YPE and V-Lab make useful recommendations on how to strengthen the sustainability and growth of entrepreneurship in Egypt. V-Lab’s other initiatives include connecting graduates with potential investors. The accelerator’s startups have played an important role during the COVID-19 pandemic by helping to create employment opportunities, both directly and indirectly.
8

Chen, Xiang, and Edgar Lara-Curzio. Reanalysis of Cost and Moist Air Oxidation Performance for CF8C-Plus and Other Alloys for AUSC Applications. Office of Scientific and Technical Information (OSTI), March 2021. http://dx.doi.org/10.2172/1782110.

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Mondal, Kanchan, Rasit Koc, and Chinbay Fan. HVOF Thermal Spray TiC/TiB2 Coatings for AUSC Boiler/Turbine Components for Enhanced Corrosion Protection. Office of Scientific and Technical Information (OSTI), December 2016. http://dx.doi.org/10.2172/1334673.

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Chiu, Chia-Yu, and Amara Sarwal. Impact of area under the curve-based vancomycin dosing combination with anti-pseudomonal beta-lactam antibiotics: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2022. http://dx.doi.org/10.37766/inplasy2022.12.0025.

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Review question / Objective: Did AUC-based vancomycin dosing reduce acute kidney injury than trough-based dosing when combined with anti-pseudomonal beta-lactam antibiotic? Condition being studied: Patients received Vancomycin combined with anti-pseudomonal beta-lactam antibiotics and monitor with either trough-base dosing or AUC-based dosing vancomycin. Information sources: All study types except case reports, case series, and conference abstracts were considered. PubMed, Embase, Cochrane Library, and ClinicalTrials.gov were searched from inception to November2022.

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