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1

Sutton, J. R., A. J. Thomas, and G. M. Davis. "Cardiovascular and Metabolic Responses to Electrical Stimulation-Induced Leg Exercise in Spinal Cord Injury." Methods of Information in Medicine 36, no. 04/05 (October 1997): 372–75. http://dx.doi.org/10.1055/s-0038-1636852.

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Abstract:Electrical stimulation-induced leg muscle contractions provide a useful model for examining the role of leg muscle neural afferents during low-intensity exercise in persons with spinal cord-injury and their able-bodied cohorts. Eight persons with paraplegia (SCI) and 8 non-disabled subjects (CONTROL) performed passive knee flexion/extension (PAS), electrical stimulation-induced knee flexion/extension (ES) and voluntary knee flexion/extension (VOL) on an isokinetic dynamometer. In CONTROLS, exercise heart rate was significantly increased during ES (94 ± 6 bpm) and VOL (85 ± 4 bpm) over PAS (69 ± 4 bpm), but no changes were observed in SCI individuals. Stroke volume was significantly augmented in SCI during ES (59 ± 5 ml) compared to PAS (46 ± 4 ml). The results of this study suggest that, in able-bodied humans, Group III and IV leg muscle afferents contribute to increased cardiac output during exercise primarily via augmented heart rate. In contrast, SCI achieve raised cardiac output during ES leg exercise via increased venous return in the absence of any change in heart rate.
2

Erasmus, Jonnro, Irene Vanderfeesten, Konstantinos Traganos, Ruud Keulen, and Paul Grefen. "The HORSE Project: The Application of Business Process Management for Flexibility in Smart Manufacturing." Applied Sciences 10, no. 12 (June 16, 2020): 4145. http://dx.doi.org/10.3390/app10124145.

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Several high-tech manufacturing technologies are emerging to meet the demand for mass customized products. These technologies include configurable robots, augmented reality and the Internet-of-Things. Manufacturing enterprises can leverage these new technologies to pursue increased flexibility, i.e., the ability to perform a larger variety of activities within a shorter time. However, the flexibility offered by these new technologies is not fully exploited, because current operations management techniques are not dynamic enough to support high variability and frequent change. The HORSE Project investigated several of the new technologies to find novel ways to improve flexibility, as part of the Horizon 2020 research and innovation program. The purpose of the project was to develop a system, integrating these new technologies, to support efficient and flexible manufacturing. This article presents the core result of the project: a reference architecture for a manufacturing operations management system. It is based on the application and extension of business process management (BPM) to manage dynamic manufacturing processes. It is argued that BPM can complement current operations management techniques by acting as an orchestrator in manufacturing processes augmented by smart technologies. Building on well-known information systems’ architecting frameworks, design science research is performed to determine how BPM can be applied and adapted in smart manufacturing operations. The resulting reference architecture is realized in a concrete HORSE system and deployed and evaluated in ten practical cases, of which one is discussed in detail. It is shown that the developed system can flexibly orchestrate the manufacturing process through vertical control of all agents, and dynamic allocation of agents in the manufacturing process. Based on that, we conclude that BPM can be applied to overcome some of the obstacles toward increased flexibility and smart manufacturing.
3

Muhsen, S., M. J. Junqueira, A. Park, J. S. Sung, S. Patil, S. Oskar, M. Morrogh, M. Morrow, and T. A. King. "Patient characteristics associated with the decision to undergo bilateral prophylactic mastectomy for lobular carcinoma in situ." Journal of Clinical Oncology 29, no. 27_suppl (September 20, 2011): 148. http://dx.doi.org/10.1200/jco.2011.29.27_suppl.148.

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148 Background: Women at increased risk for breast cancer due to a diagnosis of lobular carcinoma in situ (LCIS) have three management options: high risk surveillance +/- chemoprevention (CP) or bilateral prophylactic mastectomy (BPM). Among a large cohort of women with LCIS, we previously reported there were no differences between women choosing CP compared to those choosing surveillance alone. The purpose of this study was to identify patient factors associated with the decision to pursue BPM for LCIS. Methods: We reviewed our prospectively maintained LCIS database to identify women choosing BPM (1995-2009). Comparisons were made between patients who chose BPM versus those who chose high risk surveillance +/- CP. Results: Among 995 pts with LCIS, 795 (80%) chose surveillance alone, 149 (15%) chose CP and 51 (5%) chose BPM. Compared to patients electing surveillance +/- CP patients who pursued BPM were younger at age of LCIS diagnosis (48 vs. 52 yrs, p < 0.001), more likely to have bilateral biopsies with LCIS (14% vs. 3%, p = 0.002) and more likely to be premenopausal (82% vs. 57%, p < 0.001). Patients choosing BPM were also more likely to have additional risk factors for breast cancer including: stronger family histories and extremely dense breasts (Table). Occult breast cancer was found in 4 (8%) BPM patients. At a median follow-up of 54 months (range 0-190 mos), 120/944 (13%) patients in the surveillance +/- CP group developed breast cancer. Conclusions: High-risk surveillance alone is the preferred management option for women with LCIS at our institution. Patients electing BPM are younger and more likely to have other associated risk factors for developing breast cancer. Further research to define how the increased risk imparted by LCIS is augmented by these factors may allow for better risk stratification and more informed discussions with patients. [Table: see text]
4

Parilak, Leonard D., David G. Taylor, Yejia Song, Thomas Burkart, John C. Shryock, Anne B. Curtis, and Harm J. Knot. "Contribution of frequency-augmented inward Ca2+ current to myocardial contractility." Canadian Journal of Physiology and Pharmacology 87, no. 1 (January 2009): 69–75. http://dx.doi.org/10.1139/y08-087.

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The sarcoplasmic reticular Ca2+ pump (SERCA) is thought to be the primary determinant of heart rate-dependent increases in myocardial contractile [Ca2+]i and force (force–frequency relationship (FFR)), an important mechanism to increase cardiac output. This report demonstrates a rate-dependent role for inward Ca2+ current (ICa) in the human and rat FFR. Human action potential plateau height increased linearly with contractility when heart rate increased in vivo, as measured by monophasic action potential catheter and echocardiography. Rat rate-dependent developed force and cytosolic [Ca2+]i transients were quantified in isolated left ventricular papillary muscles, and ICa and action potential duration in cardiomyocytes. ICa and SERCA measurements better reflected [Ca2+]i and force transients than SERCA activity alone. These data support a direct and (or) indirect contribution to myocardial contractility by ICa at heart rates from approximately 1 to 3–4 Hz (60 to 180–240 bpm) in tandem with SERCA to sustain the typical ‘bell shape’ of the FFR across species.
5

Walter, L., A. Bassam, M. Davey, N. Gillian, and R. Horne. "O014 Heart rate response to obstructive respiratory events in children born preterm with OSA." SLEEP Advances 2, Supplement_1 (October 1, 2021): A7. http://dx.doi.org/10.1093/sleepadvances/zpab014.013.

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Abstract Background Preterm-born (PT) children have an increased risk for obstructive sleep apnoea (OSA) and adverse cardiovascular outcomes. Respiratory events elicit acute changes in heart rate (HR) in term-born (T) children. Whether this response is augmented in PT children with OSA remains unclear. We aimed to analyse the HR response during obstructive respiratory events in PT children with OSA. Methods Nine PT children (3–12 y), were matched for obstructive apnoea hypopnoea index (OAHI), age and gender with T children. Beat-to-beat HR was averaged 10s before, during and the peak after (post) each obstructive event, and peak HR was expressed as percentage change. Results 323 obstructive events in PT and 376 in T children were identified, consisting of 681 hypopnoeas (PT 320; T 361) and 18 apnoeas (PT 3; T 15). There were insufficient apnoeas in the PT group for analysis. For hypopnoeas during total sleep, the PT group had significantly lower HR compared to the T group before median 81bpm (IQR 74–87) vs 88 bpm (79–99); p&lt;0.001), during (76 bpm (69–83) vs 82 bpm (74–92; p&lt;0.001) and post (97 bpm (89–103) vs 105 bpm (95–115; p&lt;0.001) events. The post event increase in HR was significantly higher in the PT (26%, (16–39)) compared with the T (23%, (14–36)) group, p=0.008. Conclusion Although HR was lower during obstructive hypopnoeas in preterm compared with term-born children, the post event surge was significantly higher. This heightened HR response to respiratory events in children born preterm may underlie the worse cardiovascular outcomes in these children.
6

Masajtis-Zagajewska, Anna, Ewa Pawłowicz, and Michal Nowicki. "Effect of Short-Term Cold Exposure on Central Aortic Blood Pressure in Patients with CKD." Nephron 145, no. 1 (October 14, 2020): 20–26. http://dx.doi.org/10.1159/000510365.

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<b><i>Objectives:</i></b> Study determined effects of arterial hypertension and impaired kidney function on acute cold exposure induced changes in peripheral and central aortic blood pressure (BP). <b><i>Methods:</i></b> Five-six subjects were divided into 3 groups including 20 hypertensive patients with normal kidney function (AH-non-CKD), 20 patients with hypertension and CKD (AH-CKD) stage 3b–4 and 16 healthy normotensive subjects (C). Baseline BP, central BP, and central pulse pressure, unadjusted augmentation index (AI) and central augmented pressure were assessed by applanation tonometry (SphygmoCor) before entering the room with constant temperature −10°C (°C), after 10 min in the cold room and in same conditions in room temperature. <b><i>Results:</i></b> Cold exposure led to significant increase of central aortic, systolic, and diastolic BP in both AH-non-CKD (<i>p</i> &#x3c; 0.01) and AH-CKD (<i>p</i> &#x3c; 0.001). The central aortic BP did not change in healthy subjects. The increase of central aortic systolic blood pressure was significantly larger in AH-CKD compared to AH-non-CKD group (<i>p</i> = 0.0002). Increase of aortic central and brachial systolic and diastolic BP was significantly larger in AH-CKD and AH-non-CKD patients than in controls. AI increased and subendocardial viability ratio and heart rate decreased after cold exposure in all groups. Central aortic and brachial rate pressure product increased by approximately 2,300 bpm × mm Hg (<i>p</i> &#x3c; 0.001) and 1,600 bpm × mm Hg (<i>p</i> &#x3c; 0.001), respectively, in the AH-CKD group and by 1,000 bpm × mm Hg (<i>p</i> = 0.007) and 500 bpm × mm Hg (<i>p</i> = 0.19) in AH-non-CKD group after cold exposure. <b><i>Conclusion:</i></b> Short-term cold exposure induces larger increase of brachial and central aortic BP in patients with arterial hypertension than in healthy subjects. The changes in central aortic pressure are augmented in hypertensive patients with impaired kidney function.
7

Venkatraman, Sitalakshmi, and Ramanathan Venkatraman. "Process Innovation and Improvement Using Business Object-Oriented Process Modelling (BOOPM) Framework." Applied System Innovation 2, no. 3 (July 18, 2019): 23. http://dx.doi.org/10.3390/asi2030023.

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In the past decades, a number of methodologies have been proposed to innovate and improve business processes that play an important role in enhancing the operational efficiency of an organisation in order to attain business competitiveness. Traditional business process modelling (BPM) approaches are process-centric and focus on the workflow, ignoring the data modelling aspects that are essential for today’s data-centric landscape of modern businesses. Hence, a majority of BPM initiatives have failed in several organisations due to the lack of data-driven insights into their business performance. On the other hand, the information systems of today focus more on dataflows using object-oriented modelling (OOM) approaches. Even standard OOM approaches, such as unified modelling language (UML) methods, exhibit inherent weaknesses due to their lack of formalized innovation with business objects and the dynamic control-flows of complex business processes. In addition to these issues, both BPM and OOM approaches have been augmented with an array of complex software tools and techniques which have confused businesses. There is a lack of a common generalized framework that integrates the well-formalised control-flow based BPM approach and the dataflow based OOM approach that is suitable for today’s enterprise systems in order to support organisations to achieve successful business process improvements. This paper takes a modest step to fill this gap. We propose a framework using a structured six-step business process modelling (BPM) guideline combined with a business object-oriented methodology (BOOM) in a unique and practical way that could be adopted for improving an organisation’s process efficiency and business performance in contemporary enterprise systems. Our proposed business object-oriented process modelling (BOOPM) framework is applied to a business case study in order to demonstrate the practical implementation and process efficiency improvements that can be achieved in enterprise systems using such a structured and integrated approach.
8

Haywood, Joseph R., Teresa Craig, Julie Hensler, and Carmen Hinojosa-Laborde. "GABA-A Function and Receptor Binding in the Paraventricular Nucleus in Chronic Renal Wrap Hypertension." Hypertension 36, suppl_1 (October 2000): 701. http://dx.doi.org/10.1161/hyp.36.suppl_1.701-d.

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P48 The onset of renal wrap hypertension is associated with a reduced tonic GABA inhibition in the paraventricular nucleus (PVN) on the sympathetic nervous system. This reduced functional inhibition occurs without a change in GABA-A receptor binding in the PVN. The goal of the present study was to determine if GABAergic transmission and GABA binding is altered in chronic renal wrap hypertensive rats. Sprague-Dawley rats were made hypertensive or sham-operated. Four weeks later, animals were prepared with femoral artery catheters for the measurement of arterial pressure. Subgroups were also prepared with bilateral cannulae directed at the PVN. The renal wrap rats had higher mean arterial pressure (MAP): 139±4 mmHg vs.113±2 mmHg, but heart rate (HR) was not different (354±12 bpm vs. 369±6 bpm) as compared to control animals. Administration of the GABA-A antagonist, bicuculline, into the PVN caused a greater increase in MAP and HR in wrap animals (25±2 mmHg and 150±30 bpm) compared to sham operated rats (16±2 mmHg and 89±12 bpm). GABA-A binding sites in the PVN were estimated using in vivo autoradiography. [3H]-Flunitrazepam was used as the receptor ligand. Magnocellular neurons of the PVN showed a higher density of receptors than other areas of the nucleus. However, the number of binding sites was not different between normotensive and hypertensive rats in either the high density (1825±56 vs. 1756±41 fmol/mg protein) or low density (1454±26 vs. 1433±57 fmol/mg protein) regions of PVN. These data indicate that the inhibition by GABA in the PVN is augmented in the chronic stage of hypertension, and appears to be unrelated to a change in the number of GABA binding sites. The increased GABAergic inhibition is in contrast to the reduced inhibition that has been observed during the onset of hypertension.
9

Arita, Takeshi, George P. Sorescu, Brian T. Schuler, Laura S. Schmarkey, John D. Merlino, Jakob Vinten-Johansen, Angel R. Leon, Randolph P. Martin, and Dan Sorescu. "Speckle-tracking strain echocardiography for detecting cardiac dyssynchrony in a canine model of dyssynchrony and heart failure." American Journal of Physiology-Heart and Circulatory Physiology 293, no. 1 (July 2007): H735—H742. http://dx.doi.org/10.1152/ajpheart.00168.2007.

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Multiple echocardiographic criteria have been proposed to diagnose mechanical dyssynchrony in patients with heart failure without being validated against a model of cardiac dyssynchrony with heart failure. This study examines which of these methods can detect dyssynchrony in a canine model. Adult mongrel dogs underwent His-bundle ablation and right-ventricular pacing for 4 wk at either 110 bpm to induce dyssynchrony without heart failure (D group, n = 12) or 170 bpm to induce dyssynchrony with heart failure (DHF group, n = 9). To induce heart failure with narrow QRS, atria were paced at 190 bpm for 4 wk (HF group, n = 8). Tissue Doppler imaging (TDI) and two-dimensional echocardiography were performed at baseline and at end of study. Standard deviation of time to peak systolic velocity (color-coded TDI), time to peak S wave on pulse-wave TDI, time to peak radial and circumferential strain by speckle-tracking analysis ( Err and Ecc, respectively), and septal-to-posterior wall motion delay on M mode were obtained. In D group, only Err and Ecc were increased by dyssynchrony. In contrast, all the echocardiographic parameters of dyssynchrony appeared significantly augmented in the DHF group. Receiver-operator curve analysis showed good sensitivity of Err (90%) and Ecc (100%) to detected dyssynchrony without heart failure and excellent sensitivity and specificity of Err and Ecc to detect dyssynchrony with heart failure. Radial strain by speckle tracking is more accurate than TDI velocity to detect cardiac dyssynchrony in a canine model of dyssynchrony with or without heart failure.
10

Lazaar, Koussai, Fatma Aouaini, and Saber Gueddida. "Binuclear spin-crossover [Fe(bt)(NCS)2]2(bpm) complex: A study using first principles calculations." Journal of Chemical Physics 158, no. 14 (April 14, 2023): 144307. http://dx.doi.org/10.1063/5.0147313.

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The spin-crossover [Fe(bt)(NCS)2]2(bpm) complex is studied using spin-polarized density functional theory within the generalized gradient approximation, the Hubbard U and the weak van der Waals interactions in conjunction with the projector augmented wave method in its molecular and periodic arrangements. It is shown that the considered complex has three magnetic configurations [high spin state (HS)–HS, HS–low spin state (LS), and LS–LS] corresponding to those observed experimentally after two transition temperatures [Formula: see text] of 163 K and [Formula: see text] of 197 K. For the HS–HS magnetic state, we found that the two Fe centers are antiferromagnetically coupled for both molecular and periodic structures in good agreement with the experimental observations. Our results show that the computed total energy difference between the magnetic state configurations of the considered Fe2 complex is significantly smaller compared to those reported in the literature for other mono- or binuclear compounds.
11

Li, Chuanyi, Jidong Ge, Liguo Huang, Haiyang Hu, Budan Wu, Hao Hu, and Bin Luo. "Software cybernetics in BPM: Modeling software behavior as feedback for evolution by a novel discovery method based on augmented event logs." Journal of Systems and Software 124 (February 2017): 260–73. http://dx.doi.org/10.1016/j.jss.2016.03.013.

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12

Masutani, Satoshi, Heng-Jie Cheng, Hideo Tachibana, William C. Little, and Che-Ping Cheng. "Levosimendan restores the positive force-frequency relation in heart failure." American Journal of Physiology-Heart and Circulatory Physiology 301, no. 2 (August 2011): H488—H496. http://dx.doi.org/10.1152/ajpheart.01116.2010.

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Frequency potentiation of contractile function is a major mechanism of the increase in myocardial performance during exercise. In heart failure (HF), this positive force-frequency relation is impaired, and the abnormal left ventricular (LV)-arterial coupling is exacerbated by tachycardia. A myofilament Ca2+ sensitizer, levosimendan, has been shown to improve exercise tolerance in HF. This may be due to its beneficial actions on the force-frequency relation and LV-arterial coupling (end-systolic elastance/arterial elastance, EES/ EA). We assessed the effects of therapeutic doses of levosimendan on the force-frequency relation and EES/ EA in nine conscious dogs after pacing-induced HF using pressure-volume analysis. Before HF, pacing tachycardia increased EES, shortened τ, and did not impair EES/ EA and mechanical efficiency (stroke work/pressure-volume area, SW/PVA). In contrast, after HF, pacing at 140, 160, 180, and 200 beat/min (bpm) produced smaller a increase of EES or less shortening of τ, whereas EES/ EA (from 0.56 at baseline to 0.42 at 200 bpm) and SW/PVA (from 0.52 at baseline to 0.43 at 200 bpm) progressively decreased. With levosimendan, basal EES increased 27% (6.2 mmHg/ml), τ decreased 11% (40.8 ms), EES/ EA increased 34% (0.75), and SW/PVA improved by 15% (0.60). During tachycardia, EES further increased by 23%, 37%, 68%, and 89%; τ decreased by 9%, 12%, 15%, and 17%; and EES/ EA was augmented by 11%, 16%, 31%, and 33%, incrementally, with pacing rate. SW/PVA was improved (0.61 to 0.64). In conclusion, in HF, treatment with levosimendan restores the normal positive LV systolic and diastolic force-frequency relation and prevents tachycardia-induced adverse effect on LV-arterial coupling and mechanical efficiency.
13

Neves Rosa, Marlene C., Dara Pincegher, Rui Martins, Rui Pedro Jesus, Susana L. Lopes, Natalia Martins Martins, and Emanuel Silva. "P134: Immediate stress responses to music during psychomotor stimulation in 2 study cases with dementia." International Psychogeriatrics 35, S1 (December 2023): 135–36. http://dx.doi.org/10.1017/s1041610223002673.

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Background:The use of music in older people with advanced dementia is possible because perception, sensitivity, emotion, and memory of music may remain intact after other types of memory disappear. Previous literature is controversial about stress biomarkers response to music introduction in therapy routines for people with severe cognitive impairment and neural-behavioural disorders. Particularly, for these patients, it is possible that they feel lower pleasure levels with music-based therapies.Objective:To characterize the immediate physiological effects of listening to music during psychomotor stimulation in an old participant with combined dementia and depression disorder and in a participant with a dementia diagnosis.Methods:Two study cases with dementia diagnosis participated in this study (P1: 84yrs; male Parkinson; FAB=9; P2: 85 yrs; female; Alzheimer; FAB=11; depression diagnosis) and were submitted to psychomotor stimulation (2 sessions). The first 20 min. of each session was dedicated to psychomotor stimulation without music (A), followed by 20 minutes with music (B). Heart rate was monitored (H10 Polar sensor) in a continuous mode. Cortisol levels were collected at the beginning of the session (T0) and then repeated at periods A and B (μg/dL). The range between minimum and maximum HR values (beats per minute- bpm) and mean values for cortisol levels were considered for the stress response analysis.Results:Salivary cortisol levels were higher at T0 for P1 (0.393 vs 0.203). During period A, the P1 slightly decreased their values (↓0,076) and P2 had no changes. After introducing music, both P1 and P2 increased cortisol levels (↑0,085; 0,162↑). For both P1 and P2, a wide range of HR was detected during period B (P1: 13 vs 23 bpm) vs (P2: 15 vs 41 bpm).Conclusion:Immediate responses to the music inclusion in a psychomotor intervention caused an augmented stress response in elderly participants with dementia, especially in P2. In specific, the depression diagnosis in this participant may be associated with a low capacity to handle emotions during new experiences, causing a higher stress response.
14

Fodor, Radu, Dan Georgian Bratu, Călin Ionescu, Hassan Noor, Cornel Cheregi, and Mihai Mureșan. "Cervical Spinal Cord Transection (SCT) Increases Gastric Compliance in Anesthetized Rats." Acta Medica Transilvanica 26, no. 4 (December 1, 2021): 56–60. http://dx.doi.org/10.2478/amtsb-2021-0075.

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Abstract Spinal cord injury (SCI) can markedly alter the autonomic nervous system’s functions. It immediately causes autonomic and somatic hypo- or arreflexia, a state known as spinal shock. SCI determines the enhancement of two gastric reflexes that appear in normal conditions: the receptive and adaptative reflexes. Furthermore, this study also tried to evaluate the causes that led to such modifications: either vagal control, nitric oxide (NO)-pathways or intestine-intestinal reflexes. Male Wistar rats (N=25) were subjected to laminectomy (Sham group) or laminectomy + complete Spinal Cord Transection (SCT), between C7 and T1 vertebrae under anesthesia (SCT group). Before the surgery, the rats had water and food ad libitum; after the surgery, rats were fasted for 24 hours, still having access to water. The next day, all animals were subjected to a catheterism of their right carotid artery, a tracheostomy and a flexible balloon introduction down to the stomach’s fundix region, also under anesthesia. Rats were connected to a Power-Lab® system, via a pressure transducer (in order to measure the arterial pressure – MAP - and the heart rate - HR), and to a modified Plethysmometer (in order to measure the fundical gastric volume - GV variation). Vagal control was studied via cervical vagotomy; NO-mediation - via NO synthesis inhibitors (L-NAME); intestinointestinal reflexes - by using laxatives (Lactulone). Statistical analysis revealed, in some cases, that GV is significantly (p<0.05) augmented in SCT rats (2,4±0,09; 3,1±0,05; 3,7±0,06 ml) than in Sham (2,2±0,12; 2,9±0,12; 3,3±0,15 ml). Nevertheless, MAP and HR, were subsequently lower (p<0.05) in SCT (63,5±21,1mm Hg; 227,1±25,2 BPM) than in the control group (88,2±14,4mm Hg; 427,0±19,2 BPM). In summary, the increase of GV in SCT, seems to involve vagal pathways and/or NO-mediation, but still not neglecting the colic-gastric reflexes.
15

Uscategui, Ricardo A. R., Vívian T. Almeida, Aline E. Kawanami, Wilmer A. Z. Restan, Felipe F. P. C. Barros, Marcus A. R. Feliciano, Márcia R. F. Machado, and Wilter R. R. Vicentte. "Electrocardiographic exam in female spotted pacas (Cuniculus paca)." Pesquisa Veterinária Brasileira 36, no. 6 (June 2016): 559–63. http://dx.doi.org/10.1590/s0100-736x2016000600016.

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Abstract: Considering the limited physiological information available on neotropical rodents and the importance of this information for pathophysiological and conservation studies of these species, the aim of this study was to evaluate the cardiac electric physiology of healthy captivity spotted pacas (Cuniculus paca) under chemical restraint, due to wild nature of these animals. Eleven adult female pacas were evaluated by blood count and biochemical dosage to rule out any associate disease. Each animal was evaluated in three periods every 15 days. After chemical restraint with intramuscular midazolam 0.5mg/kg and ketamine 25mg/kg, animals were subjected to a computerized electrocardiogram, where bipolar (DI, DII and DIII) and augmented unipolar leads (aVR, aVL, aVF) were obtained. Descriptive statistics were calculated for each parameter and built the confidence interval (CI) at significance level of 95%. The electrocardiographic examination was performed without difficult. ECG tracing in DII represents a QRS complex with positive polarity, preceded by a P wave of the same polarity and proceeded by T wave of variable polarity. Heart rate mean was 150±17 bpm, and cardiac electrical axis 33.4±21.9°. All animals showed sinusal rhythm. The ECG recording technique associated with chemical restraint was well tolerated, allowing quick acquisition of reliable ECG tracings with high repeatability, which produced sufficient results to determine the heart rhythm and suggest measures of ECG complexes duration and amplitude.
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D’ Elia, S., D. Catapano, G. Cimmino, E. Pezzullo, R. Alfieri, P. Golino, and F. Loffredo. "P366 FULMINANT MYOCARDITIS WITH SPONTANEOUS RESOLUTION AFTER COVID 19 AND ALLERGIC EPISODE: MIS–A OR ALLERGIC MYOCARDITIS?" European Heart Journal Supplements 25, Supplement_D (May 2023): D187—D188. http://dx.doi.org/10.1093/eurheartjsupp/suad111.439.

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Abstract Clinical case 23–year–old male. No medical history Not vaccinated for Sars–Cov2; Recent Sars–Cov2 infection (negative antigenic swab on 03/01/22); Pharyngodynia treated with ibuprofen + ciprofloxacin and amoxicillin ac clavulanic acid(suspended for purpuric lesions on hands) After 5 days from onset of symptoms, access to PS for loss of consciousness. Laboratory: ph 7.4; Lat 3.4 EKG: sinus tachycardia HR 126 bpm ECHOCARDIOGRAM: Non–dilated left ventricle, marked reduction in FE (15%) spontaneous echocontrast in ventricular cavity chest TC: hypodense tissue in anterior mediastinum; adenopathy in peribronchial site, distended gallbladder transfer to Vanvitelli Cardiac ICU Amine support with augmented DBT for hypotension and tachycardia LAB: Tni 2193; Nt proBNP 27796; PCR 26; PCT 4; crea 1,4, Lat 1 CATH DX + EMB after 24 hours EBM: …Mixed cellularity endomyocarditis, predominantly lymphocytic, presence of eosinophils… enrollment in the MYTHS study: placebo group (saline solution) after 10 day MRI:Normal biventricular systolic function. Tissue characterization images consistent with the presence of limited area of active myocardial damage and with nonischemic pattern involving the basal segment of the infero–lateral wall of the left ventricle. Discussion The case has been a source of considerable discussion to establish the etiology of myocarditis. Although with numerous doubts, after careful evaluation of the histologic picture, the case falls under possible MIS–A (MULTISYSTEM INFLAMMATORY SYNDROME in adult) Cardiac manifestations of MIS–A include myocarditis, pericarditis, and arrhythmias, which can rapidly lead to cardiogenic shock.
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Zhang, Jing. "Practical Research on the Assistance of Music Art Teaching Based on Virtual Reality Technology." Wireless Communications and Mobile Computing 2022 (June 16, 2022): 1–13. http://dx.doi.org/10.1155/2022/8479040.

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Music education in our country has a long history, but modern teaching started relatively late. In recent years, our country has continuously accelerated the pace of learning in the field of music education. The use of advanced Internet of Things virtual reality has become an important way for the development of music art education in our country. This paper studies the practical effects of music art teaching combined with the aid of the Internet of Things virtual reality technology. This article takes the Internet of Things virtual reality technology-assisted music art teaching as the research object and analyzes the effects and advantages of virtual reality technology in music art teaching. Search for topics such as “music” and “VR” through Google to find literature related to music and art. Get the latest rankings of different types of electronic music on YouTube, and through the audition and BPM screening, download music that meets the classroom practice of this article. Research results show that a teaching system that combines VR and augmented reality technology can shorten teaching time by 65%. The virtual reconstruction of music art using VR technology allows students to visually observe the form of music art. The combination of VR technology and traditional teaching methods significantly increases the initiative, interest, effectiveness, and participation of students in learning and can achieve better teaching results. VR system is used in music teaching. DentSim system, Moog Simodont, and dental trainer system can effectively help students master the basic methods of note preparation and actively improve the teaching quality of music professional courses.
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Reddy, Ravi, Navid Resalat, Leah M. Wilson, Jessica R. Castle, Joseph El Youssef, and Peter G. Jacobs. "Prediction of Hypoglycemia During Aerobic Exercise in Adults With Type 1 Diabetes." Journal of Diabetes Science and Technology 13, no. 5 (January 17, 2019): 919–27. http://dx.doi.org/10.1177/1932296818823792.

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Background: Fear of exercise related hypoglycemia is a major reason why people with type 1 diabetes (T1D) do not exercise. There is no validated prediction algorithm that can predict hypoglycemia at the start of aerobic exercise. Methods: We have developed and evaluated two separate algorithms to predict hypoglycemia at the start of exercise. Model 1 is a decision tree and model 2 is a random forest model. Both models were trained using a meta-data set based on 154 observations of in-clinic aerobic exercise in 43 adults with T1D from 3 different studies that included participants using sensor augmented pump therapy, automated insulin delivery therapy, and automated insulin and glucagon therapy. Both models were validated using an entirely new validation data set with 90 exercise observations collected from 12 new adults with T1D. Results: Model 1 identified two critical features predictive of hypoglycemia during exercise: heart rate and glucose at the start of exercise. If heart rate was greater than 121 bpm during the first 5 min of exercise and glucose at the start of exercise was less than 182 mg/dL, it predicted hypoglycemia with 79.55% accuracy. Model 2 achieved a higher accuracy of 86.7% using additional features and higher complexity. Conclusions: Models presented here can assist people with T1D to avoid exercise related hypoglycemia. The simple model 1 heuristic can be easily remembered (the 180/120 rule) and model 2 is more complex requiring computational resources, making it suitable for automated artificial pancreas or decision support systems.
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Schobel, H. P., K. Heusser, R. E. Schmieder, R. Veelken, T. Fischer, and F. C. Luft. "Evidence against elevated sympathetic vasoconstrictor activity in borderline hypertension." Journal of the American Society of Nephrology 9, no. 9 (September 1998): 1581–87. http://dx.doi.org/10.1681/asn.v991581.

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The relationship between sympathetic nerve activity and BP in the early stages of essential hypertension remains unclear. To investigate this relationship further, this study measured resting muscle sympathetic nerve activity (MSNA: representing peripheral vasoconstrictor activity), plasma catecholamines, BP, central venous pressure, and heart rate in 20 young (24 +/- 2 SD yr), lean (body mass index, 24.2 +/- 3.0 kg/m2), male subjects with borderline hypertension (BHT) and in 21 male normotensive (NT) control subjects matched for age and body mass index. A cold pressor test was also performed to evaluate sympathetic reflex responsiveness. Resting mean BP and heart rate were significantly higher in the BHT subjects compared with NT subjects (113 +/- 9 versus 89 +/- 9 mmHg; 74 +/- 8 versus 62 +/- 8 bpm; P < 0.0001 each) with no difference in central venous pressure. Resting MSNA levels tended to be lower in the BHT versus the NT group (12 +/- 6 versus 14 +/- 9 bursts/min, P = NS; 16 +/- 8 versus 22 +/- 13 bursts/100 heartbeats, P = 0.05) and did not correlate with either BP or body mass index. Significant positive correlations were found between resting MSNA and plasma norepinephrine levels in both groups (P < 0.05). Hemodynamic and sympathetic nerve responses to the cold pressor test were similar between the BHT and NT subjects. It is concluded that resting MSNA and plasma norepinephrine levels are correlated in young lean NT and BHT men; however, neither of these variables is correlated with BP. Because MSNA was similar in the two groups, the concept that augmented resting MSNA is important in the early developmental phase of essential hypertension must be reevaluated.
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Jagatheesaperumal, Senthil Kumar, Snegha Rajkumar, Joshinika Venkatesh Suresh, Abdu H. Gumaei, Noura Alhakbani, Md Zia Uddin, and Mohammad Mehedi Hassan. "An IoT-Based Framework for Personalized Health Assessment and Recommendations Using Machine Learning." Mathematics 11, no. 12 (June 18, 2023): 2758. http://dx.doi.org/10.3390/math11122758.

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To promote a healthy lifestyle, it is essential for individuals to maintain a well-balanced diet and engage in customized workouts tailored to their specific body conditions and health concerns. In this study, we present a framework that assesses an individual’s existing health conditions, enabling people to evaluate their well-being conveniently without the need for a doctor’s consultation. The framework includes a kit that measures various health indicators, such as body temperature, pulse rate, blood oxygen level, and body mass index (BMI), requiring minimal effort from nurses. To analyze the health parameters, we collected data from a diverse group of individuals aged 17–24, including both men and women. The dataset consists of pulse rate (BPM), blood oxygen level (SpO2), BMI, and body temperature, obtained through an integrated Internet of Things (IoT) unit. Prior to analysis, the data was augmented and balanced using machine learning algorithms. Our framework employs a two-stage classifier system to recommend a balanced diet and exercise based on the analyzed data. In this work, machine learning models are utilized to analyze specifically designed datasets for adult healthcare frameworks. Various techniques, including Random Forest, CatBoost classifier, Logistic Regression, and MLP classifier, are employed for this analysis. The algorithm demonstrates its highest accuracy when the training and testing datasets are divided in a 70:30 ratio, resulting in an average accuracy rate of approximately 99% for the mentioned algorithms. Through experimental analysis, we discovered that the CatBoost algorithm outperforms other approaches in terms of achieving maximum prediction accuracy. Additionally, we have developed an interactive web platform that facilitates easy interaction with the implemented framework, enhancing the user experience and accessibility.
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Chai, Changsaar, Klufallah Mustafa, Sivaraman Kuppusamy, Aminah Yusof, Chong Shien Lim, and Soon Han Wai. "BIM Integration in Augmented Reality Model." International Journal of Technology 10, no. 7 (November 27, 2019): 1266. http://dx.doi.org/10.14716/ijtech.v10i7.3278.

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Nehdi, Atef, Polen Sean, Izzar Linares, Rodney Colina, Maritza Jaramillo, and Tommy Alain. "Deficiency in Either 4E-BP1 or 4E-BP2 Augments Innate Antiviral Immune Responses." PLoS ONE 9, no. 12 (December 22, 2014): e114854. http://dx.doi.org/10.1371/journal.pone.0114854.

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Ratnam, P. Venkata. "Integration of Augmented Reality to BIM Model." International Journal for Research in Applied Science and Engineering Technology 12, no. 3 (March 31, 2024): 2461–66. http://dx.doi.org/10.22214/ijraset.2024.59127.

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Abstract: This study investigates how to seamlessly incorporate augmented reality (AR) with Building Information Modelling (BIM) and its impact on construction efficiency. By overlaying digital information onto physical environment, AR enhances onsite decision-making and spatial understanding. The project emphasizes the practical benefits, such as improves collaboration, reduced errors, and enhanced project outcomes, positioning the AR-BIM fusion as a key driver for construction excellence.
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Alirezaei, Sahar, Hosein Taghaddos, Khashayar Ghorab, Ala Nekouvaght Tak, and Sepideh Alirezaei. "BIM-augmented reality integrated approach to risk management." Automation in Construction 141 (September 2022): 104458. http://dx.doi.org/10.1016/j.autcon.2022.104458.

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Medlin, S. C., B. Kahl, W. Longo, E. Williams, J. Lionberger, J. Kim, K. Kim, and M. Juckett. "University of Wisconsin experience treating adult ALL with the BFM regimen." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 16501. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.16501.

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16501 Background: Berlin-Frankfurt-Munster therapy (BFM) is an effective regimen for acute lymphoblastic leukemia (ALL) in children and young adults (Lancet 2:921–924,1988). Treating children and young adults at higher risk for relapse with an augmented BFM was shown to increase both event free and overall survival (NEJM 338:23,1663–1671,1998). Outcomes using standard BFM or augmented BFM in adults are unknown. Methods: This is a case-series of 29 adult patients treated with the BFM regimen. Patients were stratified into low, intermediate and high-risk groups based upon the following characteristics: age, white blood cell count, adverse cytogenetics and absence of CD 10. Low risk patients received the standard BFM regimen. Intermediate risk patients were given augmented BFM if less than 50 years old, standard BFM if older than age 50. High-risk patients received augmented BFM. Cranial irradiation was omitted in most patients (25/29). Events were defined as relapse, death from any cause, and stopping treatment for any reason. Results: Fifteen patients (median age 38, range 19–70) were treated with standard BFM and 14 patients (median age 37, range 21–72) with augmented BFM. Complete remission at day 28 was 93% (27/29). For the entire group, the 3-year overall survival was 60% with a 3-year event free survival of 45%. Patients treated with augmented BFM experienced a 3-year EFS, PFS, OS of 26%, 43%, and 48% respectively. Patients treated with standard BFM had a 3-year EFS, PFS, OS of 60%, 78%, and 78% respectively. Toxicity was common with significant neuropathy and neutropenic fever occurring in 83% and 48% respectively. Septic shock occurred in 17% of patients. Severe toxicity resulted in 1 death and discontinuation of BFM in 3 patients. The entire regimen was completed in 33 % of those treated with augmented BFM and 71% of those treated with standard BFM. Conclusion: Standard BFM is an effective and tolerable regimen for treatment of adult ALL. Augmented BFM is a difficult regimen for adult patients to complete. For both regimens, the 3-year PFS and OS compare favorably to other published regimens. No significant financial relationships to disclose.
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Hatem, Wadhah A., and Baydaa Hussain Maula. "Improving Project Monitoring by Integrating BIM with Augmented Reality." International Review of Civil Engineering (IRECE) 11, no. 6 (November 30, 2020): 304. http://dx.doi.org/10.15866/irece.v11i6.19358.

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Wang, Jun, Xiangyu Wang, Wenchi Shou, and Bo Xu. "Integrating BIM and augmented reality for interactive architectural visualisation." Construction Innovation 14, no. 4 (September 30, 2014): 453–76. http://dx.doi.org/10.1108/ci-03-2014-0019.

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Purpose – The purpose of this research is to investigate a new approach with its supporting building information modelling (BIM) + augmented reality (AR) tool to enhance architectural visualisation in building life cycle. Traditional approaches to visualise architectural design concentrate on static pictures or three-dimensional (3D) scale models which cause problems, such as expensive design evolution, lack of stakeholders’ communication and limited reusability. The 3D animated fly-throughs still occur on a computer screen in two-dimensions and seem cold and mechanical, unless done with advanced production software. Design/methodology/approach – The method of this research included case study and interview. It was, first, stated, from the building process perspective, how the BIM + AR for Architectural Visualisation System (BAAVS) was realised by integrating two types of visualisation techniques: BIM and AR, and four stages of building life cycle. Then the paper demonstrated four case studies to validate the BAAVS. Finally, four interviews were made with each case manager and team members to collect feedback on utilising BAAVS technology. Questions were asked in the areas of benefits, drawbacks and technical limitations with respect to BAAVS. Findings – Feedback from the stakeholders involved in the four cases indicated that BAAVS was useful and efficient to visualise architectural design and communicate with each other. Originality/value – This paper demonstrates BAAVS that integrated BIM and AR into architectural visualisation. The system supports an innovative performance that allows: designers to put virtual building scheme in physical environment; owners to gain an immersive and interactive experience; and property sellers to communicate with customers efficiently.
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Deebika, D. "Augmented Reality Advancement X-Ray Imaging Medical Reality scanning." Biomedical and Pharmacology Journal 8, no. 1 (June 30, 2015): 371–77. http://dx.doi.org/10.13005/bpj/623.

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Heo, Kyung-Jin, Seok-Jun Lee, and Soon-Ki Jung. "A Study of Augmented Reality based Visualization using Shape Information of Building Information Modeling." Journal of Korea Spatial Information Society 20, no. 2 (April 30, 2012): 1–11. http://dx.doi.org/10.12672/ksis.2012.20.2.001.

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Johnson, Erika M., Zoe E. Kiefer, Jamie M. Studer, Brian J. Kerr, Laura Griener, Nicholas K. Gabler, Lance H. Baumgard, and Jason W. Ross. "102 Growth Performance in Pigs fed a High Soybean Meal Diet During Heat Stress." Journal of Animal Science 101, Supplement_2 (October 28, 2023): 200–201. http://dx.doi.org/10.1093/jas/skad341.222.

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Abstract In the U.S. swine industry, feeding programs are focused on using feed ingredients that are easily digestible and cost effective. With the predicted increases in soybean processing, pig producers may have increased availability of a cost-effective protein source in soybean meal (SBM). This expanded availability of SBM may result in feeding protein above the ostensible requirements, which would likely intensify the thermic effect of digestion, potentially increasing the susceptibility of the pig to heat stress (HS). Heat stress has damaging effects on feed intake and growth performance, costing the swine industry &gt;$900 million annually. Therefore, the study objectives were to evaluate the effects of dietary crude protein diets (in the form of SBM) during HS on growth performance in growing pigs. Growing pigs (n = 40; initial BW = 55 ± 5.6 kg) were allocated into six treatments: 1) thermoneutral (TN) ad libitum control diet (TN-Ctl; n = 6), 2) TN pair-fed (PF) control diet (PF-Ctl; n = 6), 3) HS ad libitum control diet (HS-Ctl; n = 8), 4) TN ad libitum high SBM diet (TN-SBM; n = 6), 5) TN PF high SBM diet (PF-SBM; n = 6), and 6) HS ad libitum high SBM diet (HS-SBM; n = 8). The control diet included 15% crude protein (CP) while the high SBM diet included 23% CP with excess amino acids. The study consisted of two periods: Period 1 (P1; 7 d) in which all pigs were housed in TN environments (26.7 ± 1.4°C) with ad libitum access to respective diets. Period 2 (P2; 21 d), HS groups were exposed to cyclical HS with daytime temperatures reaching 35°C and evening temperatures decreased to 29.4°C. During P2, PF groups were fed to respective HS-Ctl or HS-SBM equivalents in TN conditions. Pigs exposed to HS had an overall increase in rectal temperature and respiration rate (0.91°C and 45 bpm, respectively; P ≤ 0.01) and HS-SBM pigs had increased evening rectal temperature (± 0.13°C; P ≤ 0.01), relative to HS-Ctrl. Overall, HS decreased ADFI (19%; P ≤ 0.01), ADG (26%; P ≤ 0.01) and increased F:G (10%; P ≤ 0.01) irrespective of dietary CP levels. Loin muscle area (P = 0.19) and backfat (P = 0.98) were not different between the TN and HS pigs regardless of diet. Circulating blood urea nitrogen levels did not differ between HS and TN pigs (P = 0.68), but an increase was observed in pigs fed the SBM diet relative to the control diet (P ≤ 0.01). In summary, these results demonstrate that HS decreases growth performance, but the negative effects are not augmented by feeding a high SBM diet.
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Liu, Donghai, Junjie Chen, Dongjie Hu, and Zhao Zhang. "Dynamic BIM-augmented UAV safety inspection for water diversion project." Computers in Industry 108 (June 2019): 163–77. http://dx.doi.org/10.1016/j.compind.2019.03.004.

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Burton, Jason W., Mari‐Klara Stein, and Tina Blegind Jensen. "A systematic review of algorithm aversion in augmented decision making." Journal of Behavioral Decision Making 33, no. 2 (October 23, 2019): 220–39. http://dx.doi.org/10.1002/bdm.2155.

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Zaher, Mohamed, David Greenwood, and Mohamed Marzouk. "Mobile augmented reality applications for construction projects." Construction Innovation 18, no. 2 (April 3, 2018): 152–66. http://dx.doi.org/10.1108/ci-02-2017-0013.

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Purpose The purpose of this paper is to facilitate the process of monitoring construction projects. Classic practice for construction progress tracking relies on paper reports, which entails a serious amount of manual data collection as well as the effort of imagining the actual progress from the paperwork. Design/methodology/approach This paper presents a new methodology for monitoring construction progress using smartphones. This is done by proposing a new system consisting of a newly-developed application named “BIM-U” and a mobile augmented reality (AR) channel named “BIM-Phase”. “BIM-U” is an Android application that allows the end-user to update the progress of activities onsite. These data are used to update the project’s 4D model enhanced with different cost parameters such as earned value, actual cost and planned value. The “BIM-Phase” application is a mobile AR channel that is used during construction phase through implementing a 4D “as-planned” phased model integrated with an augmented video showing real or planned progress. Findings The results from the project are then analysed and assessed to anticipate the potential of these and similar techniques for tracking time and cost on construction projects. Originality/value The proposed system through “BIM-U” and “BIM Phase” exploits the potential of mobile applications and AR in construction through the use of handheld mobile devices to offer new possibilities for measuring and monitoring work progress using building information modelling.
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Litovitz, T. A., C. J. Montrose, Reba Goodman, and Edward C. Elson. "Amplitude windows and transiently augmented transcription from exposure to electromagnetic fields." Bioelectromagnetics 11, no. 4 (1990): 297–312. http://dx.doi.org/10.1002/bem.2250110406.

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Urban, H., T. Irschik, Ch Schranz, and Ch Schönauer. "Augmented Reality im Bauwesen: Teil 2 – Baustellentaugliches Trackingsystem/Augmented Reality in Civil Engineering: Part 2 – site-compatible tracking system." Bauingenieur 95, no. 12 (2020): 501–8. http://dx.doi.org/10.37544/0005-6650-2020-12-67.

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Zusammenfassung Building Information Modeling (BIM) etabliert sich immer mehr in der Planungsphase als auch in der Ausführungsphase. Augmented Reality (AR) ermöglicht die Verwendung von BIM direkt auf der Baustelle und fördert somit den verstärkten Einsatz von BIM im Bauprozess. Sowohl Tablets als auch Datenbrillen können für AR zum Einsatz kommen. Datenbrillen bieten aus Sicht der Autoren in Zukunft einige wichtige Vorteile für den Einsatz auf der Baustelle – bei ihnen bleiben zum Beispiel die Hände frei. Für einen produktiven Einsatz der AR-Datenbrille ist die jederzeit richtige Positionierung (auch Tracking genannt) des virtuellen Modells auf der Baustelle essentiell. Die Baustelle stellt dabei aufgrund der äußeren Rahmenbedingungen große Herausforderungen an das Trackingsystem. Viele Oberflächen sind relativ gleichmäßig grau oder weiß. Suboptimale Lichtverhältnisse und kaum dauerhafte Erkennungspunkte erschweren zusätzlich das Tracking. Im Projekt AR-AQ-Bau beschäftigen sich die Autoren mit der Übertragung von BIM auf die Baustelle mittels AR-Datenbrillen und führten dazu verschiedene Trackingtests durch. Dieser Artikel zeigt vorhandene Probleme und mögliche Lösungen für das Tracking des AR-Modells auf Baustellen.
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An, Ji-Yean, Jeong-Min Choi, Soon-Ho Kwon, Doo-Hyung Song, and Jong-Ho Ock. "A Study on the Development of the Project Management System based on Augmented Reality." Journal of the Korea Academia-Industrial cooperation Society 11, no. 8 (August 31, 2010): 3083–93. http://dx.doi.org/10.5762/kais.2010.11.8.3083.

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Schranz, Christian, Harald Urban, and Alexander Gerger. "Potentials of Augmented Reality in a BIM based building submission process." Journal of Information Technology in Construction 26 (July 26, 2021): 441–57. http://dx.doi.org/10.36680/j.itcon.2021.024.

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The digital transformation in the construction industry, which is also referred to as Construction 4.0, is gaining impact in recent years. BIM as the central point for model-based planning and communication is at the centre of this development. This paves the way for the implementation of further technologies, such as augmented reality (AR) or artificial intelligence (AI) in the construction process. However, the submission process currently receives little attention in the BIM project cycle, even though it has a significant impact on a building project. There is a huge potential for the application of BIM and AR in the building submission process. BIM allows partly automatic compliance checks to be performed. The BIM model and the results of these checks can be used as basis for the AR model. This paper investigates an application for AR in a BIM submission process. Here we show that especially the plan check process and hearings in the approval process can be improved and sped up by combining BIM and the visualization technology of AR. In this process, AR can support the building authority in checking the compliance with building regulations. Additionally, non-experts involved often have problems grasping the planned building project just based on the technical 2D plans. In this case, AR helps them to visualise the impact of the planned project and allows for better judgement. Use-cases are presented, showing strategies to improve the plan check process and assist the building authority as well as the persons involved, for both experts as well as non-experts. Finally, the requirements, technical implementations, and effects of an AR application for the plan check process are described. An AR-supported plan checking process can vastly improve the presentation of technical content. This leads to better understanding and more transparency for non-experts. Because AR is relatively easy to use, it might become ubiquitous not only to experts, but also to the general public.
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Hajji, R., A. Kharroubi, Y. Ben Brahim, Z. Bahhane, and A. El Ghazouani. "INTEGRATION OF BIM AND MOBILE AUGMENTED REALITY IN THE AECO DOMAIN." International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLVI-4/W3-2021 (January 10, 2022): 131–38. http://dx.doi.org/10.5194/isprs-archives-xlvi-4-w3-2021-131-2022.

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Abstract. BIM (Building Information Modeling) is increasingly present in a wide range of applications (architecture, engineering, construction, land use planning, utility management, etc.). BIM allows better management of projects through precise planning, communication and collaboration between several stakeholders as well as facilitating the monitoring of project operations. The emergence of Augmented Reality (AR) technology allows the superposition of (2D, 3D) information directly on the physical world, so generating immersive, interactive and enriching experiences for the user. To take advantages of BIM and AR potential in the interaction and the intuitive management in AECO (Architecture, Engineering, Construction and Operation) projects, we propose a BIM-based AR workflow through an application called "EasyBIM". This latter allows access and interaction with a BIM model through functionalities for measurement, data consultation, collaboration, visualization and integration of information from sensors. The application is developed for mobile platforms (tablet, smartphone), and has as input an IFC file (Industry Foundation Classes). Promising test results show that the developed solution can be easily integrated into a BIM context for several use cases: marketing, collaboration, site monitoring, facility management, etc.
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Gray, P. C., and S. Choe. "Design-augmented (DA) biologics: BMP chimeras for bone and cartilage regeneration." Osteoarthritis and Cartilage 28, no. 2 (February 2020): 123–25. http://dx.doi.org/10.1016/j.joca.2019.09.004.

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Machado, Ricardo L., and Cesar Vilela. "CONCEPTUAL FRAMEWORK FOR INTEGRATING BIM AND AUGMENTED REALITY IN CONSTRUCTION MANAGEMENT." JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT 26, no. 1 (January 22, 2020): 83–94. http://dx.doi.org/10.3846/jcem.2020.11803.

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The need for systematic data collection and processing to generate real-time building site progress information is critical. Building Information Modelling (BIM) provides the benefit of aggregating information about the building site on a single platform. Augmented reality (AR) emerges to enhance BIM concerning visualization of the building site, through processing and automatic absorption of information. This work aims to analyse the potential of AR association to BIM, by adopting an approach based on literature review. Trends in contemporary research are checked by categorizing applied research methods, areas of expertise, and AR technologies. Publications produced between 2008 and 2018 from journals of architecture, engineering, and construction areas in databases Web of Science, SciSearch, SCOPUS, INSPEC, Google Scholar, Academic OneFile, EBSCO, OCLC, VINITI, SCImago, and ProQuest were investigated. As main results, it was found that the case study approach was adopted in 41% of the publications analysed. The building site inspection was the research object in 48% of papers. Fiducial markers, GIS/GPS, laser scanners, and photogrammetry emerged as main options for automatic data capture on the progress of the building site. Integration between AR and BIM has the potential to solve information processing problems and improving construction management.
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Meža, Sebastjan, Žiga Turk, and Matevž Dolenc. "Component based engineering of a mobile BIM-based augmented reality system." Automation in Construction 42 (June 2014): 1–12. http://dx.doi.org/10.1016/j.autcon.2014.02.011.

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Chen, Yi-Jao, Yong-Shan Lai, and Yen-Han Lin. "BIM-based augmented reality inspection and maintenance of fire safety equipment." Automation in Construction 110 (February 2020): 103041. http://dx.doi.org/10.1016/j.autcon.2019.103041.

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Dostál, Z., A. Friedlander, S. A. Santos, and J. Malík. "Analysis of semicoercive contact problems using symmetric BEM and augmented Lagrangians." Engineering Analysis with Boundary Elements 18, no. 3 (October 1996): 195–201. http://dx.doi.org/10.1016/s0955-7997(96)00048-3.

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Pa Pa Win, Aung, Woonggyu Choi, Gichun Cha, and Seunghee Park. "Development of Large-capacity BIM Optimization and Augmented Reality Visualization Technology." Journal of Construction Automation and Robotics 2, no. 1 (April 30, 2023): 7–12. http://dx.doi.org/10.55785/jcar.2.1.7.

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Kong, Heather, and Sanjeev Sabharwal. "Fixator-augmented flexible intramedullary nailing for osteopenic femoral shaft fractures in children." Journal of Pediatric Orthopaedics B 25, no. 1 (January 2016): 11–16. http://dx.doi.org/10.1097/bpb.0000000000000237.

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Raziapov, Ruslan. "Application of augmented reality methods in construction." Earthquake Engineering. Construction Safety, no. 4 (August 25, 2021): 19–27. http://dx.doi.org/10.37153/2618-9283-2021-4-19-27.

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The application of virtual augmented reality (AR) in the construction industry based on the use of information modeling technologies (BIM) has great prospects. An augmented reality space with a presence effect can facilitate better interaction between customers and specialists in various technical issues related to the implementation of the construction project. Combined with the concept of building information modeling, AR technologies can improve the general understanding of the construction process. Using the newest augmented reality technologies allows you to work out both the entire project and its individual details as accurately as possible. Object visualization in the real world can be improved by combining AR as well as BIM technologies, since the interactive capabilities provided by AR software and access to BIM information data allow you to more intuitively solve the tasks of maintenance and construction management. This article analyzes the current state of augmented reality technologies in construction, identifies the problems and prospects of using these innovative technologies in the construction sector, describes the methods of using the latest technologies under study in the construction sector, and also presents indicators affecting decision-making using augmented reality technologies. The article considers the possibility of reducing the implementation time of certain stages of investment and construction activities taking into account the introduction of augmented reality, provides examples of construction companies from different countries developing software and development companies using augmented reality technologies for marketing purposes, and concludes that augmented reality is promising in construction.
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Tomita, Takashi, Mariko Onishi, Eiji Sato, Yasuhiro Kimura, and Kenji Kihira. "Gatifloxacin Induces Augmented Insulin Release and Intracellular Insulin Depletion of Pancreatic Islet Cells." Biological & Pharmaceutical Bulletin 30, no. 4 (2007): 644–47. http://dx.doi.org/10.1248/bpb.30.644.

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Betz, Randal R., William Francis Lavelle, Mary Jane Mulcahey, and Amer F. Samdani. "Histology of a fusion mass augmented with demineralized bone matrix for congenital scoliosis." Journal of Pediatric Orthopaedics B 20, no. 1 (January 2011): 37–40. http://dx.doi.org/10.1097/bpb.0b013e32833eeaaa.

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Khalek, Imad A., Jad M. Chalhoub, and Steven K. Ayer. "Augmented Reality for Identifying Maintainability Concerns during Design." Advances in Civil Engineering 2019 (March 3, 2019): 1–12. http://dx.doi.org/10.1155/2019/8547928.

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Abstract:
In a building context, decisions made early in the design phase can have a major impact on maintainability of the resulting facility. Effectively leveraging the knowledge of facility management teams in the design stage can lead to improved maintainability in the operation phase, but this feedback can be challenging to elicit during the design stage because facility management teams may not be formed by the time of design. This requires designers, who may not have facility management experience, to think like facility managers in order to consider the needs of the maintenance teams. This paper examines the extent to which different visualization media may be able to enable individuals without prior maintenance experience to identify maintainability concerns in a design model. Student participants, without prior maintenance experience, were randomly assigned to explore a design to assess maintainability concerns with either augmented reality (AR) or a traditional computer screen for viewing a Building Information Model (BIM). Their perceptions, behaviors, and statements were recorded and analyzed. Results indicate that BIM supports better identification of potentially problematic areas, but AR allows users to more consistently determine why an area is problematic. This suggests an opportunity to use a hybrid BIM/AR approach for identifying and resolving maintainability considerations during the design phase. The findings from this work provide evidence to illustrate how AR and BIM may enable individuals with limited experience to be able to effectively think like facility managers in order to make better maintainability decisions during design to lead to a better building during operation.
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Ji, Seung-Yeul, Mi-Kyoung Kim, and Han-Jong Jun. "Space Management on Campus of a Mobile BIM-based Augmented Reality System." Architectural research 19, no. 1 (March 31, 2017): 1–6. http://dx.doi.org/10.5659/aikar.2017.19.1.1.

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