Dissertations / Theses on the topic 'Attentive Mechanisms'
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PROIETTI, VALENTINA MARIA. "How early and later-acquired experience affects the age bias in face recognition: an exploration of age-of-acquisition effects." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2015. http://hdl.handle.net/10281/75273.
Full textFitzgerald, Marilyn. "Are attention bias and interpretation bias reflections of a single common mechanism or multiple independent mechanisms?" University of Western Australia. School of Psychology, 2008. http://theses.library.uwa.edu.au/adt-WU2009.0052.
Full textKerr, John H. "Arousal mechanisms, attention and sports performance." Thesis, University of Nottingham, 1988. http://eprints.nottingham.ac.uk/10947/.
Full textGama, Nuno. "Mechanisms of multisensory integration and attention." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/40400/.
Full textOwen, Adrian Mark. "Fronto-striatal mechanisms in planning and attention." Thesis, King's College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302625.
Full textGontrum, Johannes. "Attention Mechanisms for Transition-based Dependency Parsing." Thesis, Uppsala universitet, Institutionen för lingvistik och filologi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-395491.
Full textKennett, Steffan Anthony. "Links in spatial attention between touch and vision." Thesis, Birkbeck (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343623.
Full textSantangelo, Valerio. "Multimodal investigation on spatial attention mechanisms: a model of shared attention resources (ShAR)." Doctoral thesis, La Sapienza, 2005. http://hdl.handle.net/11573/917227.
Full textTattersall, A. J. "Divided attention and the structure of temporary memory." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382717.
Full textPaltoglou, Aspasia Eleni. "Mechanisms of spatial and non-spatial auditory selective attention." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/10697/.
Full textBeuth, Frederik. "Visual attention in primates and for machines - neuronal mechanisms." Universitätsverlag Chemnitz, 2017. https://monarch.qucosa.de/id/qucosa%3A35655.
Full textVisuelle Aufmerksamkeit ist ein wichtiges kognitives Konzept für das tägliche Leben des Menschen. Es ist aber immer noch nicht komplett verstanden, so dass es ein langjähriges Ziel der Neurowissenschaften ist, das Phänomen grundlegend zu durchdringen. Gleichzeitig wird es aufgrund des mangelnden Verständnisses nur selten in maschinellen Sehsystemen in der Informatik eingesetzt. Das Verständnis von visueller Aufmerksamkeit ist jedoch eine komplexe Herausforderung, da Aufmerksamkeit äußerst vielfältige und scheinbar unterschiedliche Aspekte besitzt. Sie verändert multipel sowohl die neuronalen Feuerraten als auch das menschliche Verhalten. Daher ist es sehr schwierig, eine einheitliche Erklärung von visueller Aufmerksamkeit zu finden, welche für alle Aspekte gleichermaßen gilt. Um dieses Problem anzugehen, hat diese Arbeit das Ziel, einen gemeinsamen Satz neuronaler Mechanismen zu identifizieren, welche sowohl den neuronalen als auch den verhaltenstechnischen Aspekten zugrunde liegen. Die Mechanismen werden in neuro-computationalen Modellen simuliert, wodurch ein einzelnes Modellierungsframework entsteht, welches zum ersten Mal viele und verschiedenste Phänomene von visueller Aufmerksamkeit auf einmal erklären kann. Als Aspekte wurden in dieser Dissertation multiple neurophysiologische Effekte, Realwelt Objektlokalisation und ein visuelles Maskierungsparadigma (OSM) gewählt. In jedem dieser betrachteten Felder wird gleichzeitig der State-of-the-Art verbessert, um auch diesen Teilbereich von Aufmerksamkeit selbst besser zu verstehen. Die drei gewählten Gebiete zeigen, dass der Ansatz grundlegende neurophysiologische, funktionale und verhaltensbezogene Eigenschaften von visueller Aufmerksamkeit erklären kann. Da die gefundenen Mechanismen somit ausreichend sind, das Phänomen so umfassend zu erklären, könnten die Mechanismen vielleicht sogar das essentielle neuronale Substrat von visueller Aufmerksamkeit im Cortex darstellen. Für die Informatik stellt die Arbeit damit ein tiefergehendes Verständnis von visueller Aufmerksamkeit dar. Darüber hinaus liefert das Framework mit seinen neuronalen Mechanismen sogar eine Referenzimplementierung um Aufmerksamkeit in zukünftige Systeme integrieren zu können. Aufmerksamkeit könnte laut der vorliegenden Forschung sehr nützlich für diese sein, da es im Gehirn eine Aufgabenspezifische Optimierung des visuellen Systems bereitstellt. Dieser Aspekt menschlicher Wahrnehmung fehlt meist in den aktuellen, starken Computervisionssystemen, so dass eine Integration in aktuelle Systeme deren Leistung sprunghaft erhöhen und eine neue Klasse definieren dürfte.:1. General introduction 2. The state-of-the-art in modeling visual attention 3. Microcircuit model of attention 4. Object localization with a model of visual attention 5. Object substitution masking 6. General conclusion
Wallis, George J. "Selection mechanisms for working memory." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:1a9be8d6-9f8e-49af-8185-8be4c890010f.
Full textCohen, Jason C. "Attention mechanisms and inhibition of return in the somatosensory system." Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available full text, 2002. http://wwwlib.umi.com/cr/syr/main.
Full textYan, Shiyang. "Visual attention mechanism in deep learning and its applications." Thesis, University of Liverpool, 2018. http://livrepository.liverpool.ac.uk/3028892/.
Full textSock, Ching Low. "Giving centre stage to top-down inhibitory mechanisms for selective attention." Doctoral thesis, Universitat Pompeu Fabra, 2020. http://hdl.handle.net/10803/670753.
Full textL’atenció selectiva determina els senyals sensorials que es processen a nivells superiors a costa dels altres. Està esbiaixada per regions cerebrals d’ordre superior que anticipen estímuls rellevants per a la tasca i augmenten la sensibilitat neuronal a l’escorça sensorial. Sovint, es creu que això es produeix mitjançant l'excitació de neurones seleccionades, però alguns estudis han suggerit que no és la descripció completa del procés. Cada vegada més, l’evidència apunta cap a un mecanisme alternatiu de polarització inhibitiva de dalt a baix. Aquí hem investigat, aleshores, un model d’atenció inhibitori. Primer, vam demostrar com es redueix la sensibilitat a les funcions d’estímul irrellevants per tasques mitjançant la supressió de dalt a baix. En segon lloc, vam demostrar la capacitat d’un model d’espiga basat en la biologia per modular el processament de la informació i l’hem comparat amb la fisiologia. Per últim, hem explorat la interacció entre els models excitadors i inhibidors d’atenció de dalt a baix en un agent de cerca d’aliments. Els nostres resultats donen suport al model inhibitori de l’atenció de dalt a baix com a mecanisme d’atenció biològica i mostren com s’adapta al ‘zeitgeist’ actual dels mecanismes d’atenció de dalt a baix.
Burton, Pamela Ann. "Physiological evidence of interactive object-based and space-based attention mechanisms." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 50.79Mb,139 p, 2005. http://wwwlib.umi.com/dissertations/fullcit/3157279.
Full textCristescu, Tamara C. "Flexible mechanisms for orienting attention to words in the human brain." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442831.
Full textAustin, Alison J. "Mechanisms of attention for cues associated with rewarding and aversive outcomes." Thesis, University of Sussex, 2010. http://sro.sussex.ac.uk/id/eprint/6265/.
Full textKulke, L. V. "Cortical mechanisms of visual attention in typically developing infants and adults." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1471117/.
Full textIsunza, Navarro Abgeiba Yaroslava. "Evaluation of Attention Mechanisms for Just-In-Time Software Defect Prediction." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-288724.
Full textJust-In-Time Defect Prediction (JIT-DP) fokuserar på att förutspå fel i mjukvara vid ändringar i koden, med målet att hjälpa utvecklare att identifiera defekter medan utvecklingsprocessen fortfarande är pågående, och att förbättra kvaliteten hos applikationsprogramvara. Detta arbete studerar djupinlärningstekniker genom att tillämpa attentionmekanismer som har varit framgångsrika inom, bland annat, språkteknologi (NLP). Vi introducerar två nätverk vid namn Convolutional Neural Network with Bidirectional Attention (BACNN), och Bidirectional Attention Code Network (BACoN), som använder en tvåriktad attentionmekanism mellan koden och meddelandet om en mjukvaruändring. Dessutom undersöker vi BERT [17] och RoBERTa [57], attentionarkitekturer för JIT-DP. Mer specifikt studerar vi hur effektivt dessa attentionbaserade modeller kan förutspå defekta ändringar, och jämför dem med de bästa tillgängliga arkitekturerna DeePJIT [37] och TLEL [101]. Våra experiment utvärderar modellerna genom att använda mjukvaruändringar från det öppna källkodsprojektet OpenStack. Våra resultat visar att attentionbaserade nätverk överträffar referensmodellen sett till träffsäkerheten i de olika scenarierna. De attentionbaserade modellerna, framför allt BERT och RoBERTa, demonstrerade lovade resultat när det kommer till att identifiera defekta mjukvaruändringar och visade sig vara effektiva på att förutspå defekter i ändringar av nya mjukvaruversioner.
Baker, Christopher A. "Differentiating attention and motor system-based mechanisms underlying concealed knowledge detection /." Diss., Digital Dissertations Database. Restricted to UC campuses, 2008. http://uclibs.org/PID/11984.
Full textLisi, Matteo. "Mechanisms of top-down visual spatial attention: computational and behavioral investigations." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3423038.
Full textQuesta tesi verte sull’indagine dei meccanismi alla base dell'attenzione visuo-‐spaziale e In particolare sull'attenzione top-‐down. Con questo termine si intende la capacità di selezionare le informazioni rilevanti e scartare quelle irrilevanti in maniera volontaria e sulla base dei nostri obiettivi. Il cervello umano non è in grado di processare allo stesso livello tutte le informazioni disponibili nell’ambiente in un dato momento, per questo una selezione corretta dell’informazione da elaborare è fondamentale anche per l’esecuzione delle più semplici attività quotidiane. Prestare attenzione ad informazioni irrilevanti può farci trascurare altre informazioni di importanza cruciale, con conseguenze potenzialmente gravi. Nel primo studio (capitolo 2) I affronterò con un approccio computazionale la questione dei meccanismi neurali che sottendono l’attenzione visuo-‐spaziale: quali sono le basi neurali dell’attenzione visuo-‐spaziale? Secondo la teoria premotoria, orientare l'attenzione verso una specifica posizione spaziale equivale a preparare un movimento oculare verso la medesima posizione, un’ipotesi supportata dai risultati di molteplici studi di neuroimaging e neurofisiologici, i quali hanno mostrato una notevole sovrapposizione tra i circuiti dedicati all’attenzione visiva e la programmazione di movimenti oculari. In questo capitolo presenterò un modello computazionale in grado di spiegare diversi effetti attentivi senza richiedere l’aggiunta di meccanismi specifici oltre ai circuiti oculomotori. Inoltre include un meccanismo, modellato sulla base di dati neurofisiologici, che consente di anticipare le conseguenze sensoriali di un movimento oculare sulla rappresentazione spaziale interna al modello, e di spiegare alcune recenti dimostrazioni di dissociazione tra attenzione e movimenti oculari che possono essere utilizzate per confutare la teoria premotoria. Nel capitolo successivo presenterò un secondo modello computazionale (capitolo 3) con lo scopo di investigare ulteriormente i meccanismi computazionali alla base delle trasformazioni sensorimotorie, cioè i processi che traducono l’informazione sensoriale in appropriati comandi motori. In particolare mostrerò che una rappresentazione spaziale costituita da neuroni con campi recettivi retinocentrici ,modulati in ampiezza da un segnale posturale, è sia efficiente (al fine di trasformare l’informazione visiva in coordinate motorie centrate su un effettore) che plausibile, in quanto emerge in un modello di rete neurale addestrato in maniera non supervisionata (usando cioè solo segnali disponibili localmente a livello  del singolo neurone). Questo risultato supporta inoltre l’approccio utilizzato nel primo modello presentato. Successivamente presenterò una serie di studi comportamentali: nel primo (capitolo 4), mostrerò che la costanza spaziale dell’attenzione visiva rispetto ai movimenti oculari (cioè la capacità di mantenere stabilmente l'attenzione in un punto nello spazio attraverso successivi movimenti oculari), dipende fortemente da alcune proprietà dell'immagine, vale a dire la presenza continua di punti di riferimento visivi. Questo risultato aiuta a risolvere recenti controversie sull’orientamento dell’attenzione durante movimenti oculari. Nel secondo studio comportamentale (capitolo 5), indagherò un aspetto spesso trascurato relativo al paradigma di cueing spaziale (probabilmente la tecnica più utilizzata nello studio dell’attenzione spaziale): la predittività del cue (cioè la misura in cui il cue spaziale indica correttamente la posizione in cui apparirà lo stimolo bersaglio). I risultati mostrano che, indipendentemente dalla consapevolezza dei partecipanti, variazioni nella predittività producono corrispondenti variazioni degli effetti di validità del cue, e che effetti significativi di validità possono comparire anche in assenza di un cue predittivo o direzionale. Questi risultati mettono in dubbio l’appropriatezza dell’uso di cue predittivi per indagare spostamenti volontari dell’attenzione spaziale. Infine, nell'ultimo studio userò una misura psicofisiologica, il diametro della pupilla, per indagare gli aspetti relativi all’intensità del processamento visuospaziale. In particolare mostrerò come dilatazioni della pupilla evento-‐relate riflettano accuratamente variazioni nella performance in un compito di monitoraggio spaziale provocate dall’aggiunta di un doppio-‐compito. Inoltre, i risultati del compito primario spaziale rivelano la presenza di un bias consistente verso l’emispazio di destra, indicato da una percentuale maggiore di bersagli omessi nell’emispazio di sinistra. In particolare il pattern di errori rispecchia il fenomeno dell’estinzione (mancata risposta a uno stimolo quando è presentata simultaneamente con un secondo stimolo, tipicamente nell’emispazio opposto) che si trova spesso in pazienti con danno cerebrale unilaterale. In conclusione, dagli studi presentati emerge un quadro dell’attenzione volontaria visuo-‐spaziale come un meccanismo complesso, che, anche nei suoi aspetti volitivi è fortemente influenzato da altri fattori, non volitivi, sia esterni che interni all'individuo
Hayes, Taylor Ray. "Mechanisms of Visual Relational Reasoning." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1416933187.
Full textHighlander, Tyler Clayton. "Conditional Dilated Attention Tracking Model - C-DATM." Wright State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1564652134758139.
Full textKoleszar, Thomas W. "The generation of IPDP micropulsations, with special attention to frequency shift mechanisms." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/29132.
Full textScience, Faculty of
Earth, Ocean and Atmospheric Sciences, Department of
Graduate
West, Vicki Hopfinger Joseph B. "Comparisons of the neural mechanisms of voluntary, reflexive, and socially-directed attention." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,747.
Full textTitle from electronic title page (viewed Dec. 18, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Psychology." Discipline: Psychology; Department/School: Psychology.
Carmel, David Podhorzer. "Top-down control of visual attention and awareness : cognitive and neural mechanisms." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1444603/.
Full textMacNamara, Kailey. "Behavioral and Neural Mechanisms of Social Heterogeneity in Attention Deficit/Hyperactivity Disorder." FIU Digital Commons, 2017. http://digitalcommons.fiu.edu/etd/3390.
Full textWalters-Symons, Rosanna Mary. "Attention, gaze, response programming : examining the cognitive mechanisms underpinning the quiet eye." Thesis, University of Exeter, 2017. http://hdl.handle.net/10871/28336.
Full textO'Dea, Namrita Kumar. "Fatigue mechanisms in sedentary and endurance trained adults: effects of nutritional countermeasures." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/53584.
Full textBretherton, Paul. "The neural mechanisms of attention : exploring threat-related suppression and enhancement using ERPs." Thesis, University of Roehampton, 2016. https://pure.roehampton.ac.uk/portal/en/studentthesis/the-neural-mechanisms-of-attention(87e183ac-3a36-40e6-9c69-91f7c1209e87).html.
Full textStephenson, Lisa. "Follow my lead : behavioural and neural mechanisms of gaze leading in joint attention." Thesis, University of East Anglia, 2018. https://ueaeprints.uea.ac.uk/68417/.
Full textRaafat, R. M. "Attention and automaticity in social judgments from facial appearance : cognitive and neural mechanisms." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1468622/.
Full textMartel, Michelle M. "Hormonal associations with childhood ADHD and associated trait and neuropsychological mechanisms." Diss., Connect to online resource - MSU authorized users, 2007.
Find full textParker, Amanda Louise. "A cross-modal investigation into the relationships between bistable perception and a global temporal mechanism." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/9545.
Full textMagimairaj, Beula M. "Attentional mechanisms in children's complex memory span performance." Ohio : Ohio University, 2010. http://www.ohiolink.edu/etd/view.cgi?ohiou1267650640.
Full textChen, Guozhang. "Dynamical and computational mechanisms of biological and artificial neural circuits." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23710.
Full textPatriquin, Michelle A. "Music and Children with Autism Spectrum Disorders: Potential Autonomic Mechanisms of Social Attention Improvement." Thesis, Virginia Tech, 2010. http://hdl.handle.net/10919/77008.
Full textMaster of Science
Napolitano, Amanda C. "Modality dominance in young children underlying mechanisms and broader implications /." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1146171556.
Full textElshafei, Hesham. "Neurophysiological Mechanisms of Auditory Distractibility in the Healthy, Aging or Damaged Human Brain." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSE1255/document.
Full textTop-down (TD) and bottom-up (BU) mechanisms of attention are supported by dorsal and ventral networks that mainly overlap in the lateral prefrontal cortex (lPFC). A balance between these mechanisms is essential, yet rarely investigated. Increased distractibility observed during ageing or after frontal damage could result from jeopardizing this balance. It has been proposed that distinct oscillatory frequencies support the activation of these two attention networks. Our main aim was to test, in the auditory modality, whether (1) alpha oscillations would coordinate activity within the dorsal TD network, (2) gamma activity would index the activation of the ventral BU network, (3) the lPFC would support the balance between these networks through oscillatory coupling. We also aimed to investigate the oscillatory correlates of the increased distractibility associated with ageing or frontal damage. MEEG data were recorded while participants performed the Competitive Attention Test, which enables simultaneous investigation of BU and TD attention mechanisms. We showed that alpha oscillations indexed facilitatory and suppressive mechanisms of TD attention, and communication within the dorsal network; while gamma oscillations indexed the ventral network activation. Moreover, the lPFC subtended communication in the two networks; with the TD/BU interaction occurring in the medial PFC. We also showed that ageing-related distractibility was of TD deficit origin. Finally, preliminary results suggest that lPFC damage can impact both TD and BU attention. This thesis provides novel insights into the brain oscillatory dynamics of the TD/BU attentional balance supporting distractibility
Raykos, Bronwyn C. "Attentional and interpretive biases : independent dimensions of individual difference or expressions of a common selective processing mechanism?" University of Western Australia. School of Psychology, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0018.
Full textRohenkohl, Gustavo. "Temporal orienting in the human brain : neural mechanisms of control and modulation." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:95d78d46-6398-48ce-8ff9-30b4fd192e3f.
Full textWang, Jing. "Hyperspectral Image Classification Based on Deep Learning and Module Inspired by Human Attention Mechanism." Thesis, Griffith University, 2020. http://hdl.handle.net/10072/397634.
Full textThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Info & Comm Tech
Science, Environment, Engineering and Technology
Full Text
Wilson, Steven. "Mechanisms of attention and awareness : parameters and assessment of pre-attentional awareness using change blindness task." Thesis, University of Lincoln, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496078.
Full textMoadab, Ida. "The Role of Mindfulness and Self-Compassion in the Neural Mechanisms of Attention and Self-Monitoring." Thesis, University of Oregon, 2013. http://hdl.handle.net/1794/13402.
Full textBuonocore, Antimo. "Remote distractor effects in saccadic, manual and covert attention tasks." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/5850.
Full textMagimairaj, Beula M. "Attentional Mechanisms in Children’s Complex Memory Span Performance." Ohio University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1267650640.
Full textDoherty, Jason Michael. "What limits dual-tasking in working memory? : an investigation of the effect of sub-task demand on maintenance mechanisms employed during dual-tasking." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/25884.
Full textGarcía, García Manuel Antonio. "The role of COMT, DAT and DRD2 polymorphisms on brain mechanisms of involuntary attention and cognitive control." Doctoral thesis, Universitat de Barcelona, 2009. http://hdl.handle.net/10803/2722.
Full textThe results of these studies provide evidence for a relevant role of COMT, DAT1 and DRD2 genes in cognitive processes, which helps to understand cognitive disruption associated to dopamine dysregulation in psychiatric disorders.
Els nostres gens juguen un rol important en la manera que enfrontem els canvis de l'ambient i adaptem la nostre conducta adequadament. El present treball de recerca se centra en el paper de tres gens relacionats amb la dopamina (DA) sobre processos cognitius, com el canvi de l'atenció quan és requerit per les demandes ambientals o el processament d'esdeveniments inesperats però potencialment rellevants. L'activitat dopaminèrgica al còrtex prefrontal (PFC) i a l'estriat semblen jugar papers diferents en el processament atencional i interaccionen per a regular l'estabilitat i flexibilitat de l'actualització de la informació contextual. Per això, vam estudiar l'acció de gens que regulaven l'acció de la dopamina del PFC (i.e. Catechol-O-Methyltransferase; COMT), la resposta de dopamina difosa en l'espai extrasinàptic estriatal (i.e. Transportador de Dopamina; DAT) i la concentració de receptors de dopamina de tipus D2 (i.e. receptors D2 de dopamina; DRD2).
Els participants amb diversos al·lels dels gens estudiats van realitzar dues versions diferents d'un paradigma de distracció auditiu visual, en el qual se'ls demanava que ignoressin tons estàndards freqüents i sons ambientals nous rars que precedien els objectius pertinents de la tasca. En dos estudis, vam manipular l'efecte d'un context emocional sobre el processament d'esdeveniments nous inesperats, donada la potencial rellevància d'un esdeveniment nou durant una situació d'amenaça en la qual pot ser nociu. En tres estudis, els participants amb al·lels diferents o combinacions d'al·lels van realitzar un paradigma de commutació de tasca, en el qual l'actualització d'informació sensorial i de tasca es podria dissociar. Al llarg dels sis estudis, se van emprar mesures conductuals i electrofisiològiques enregistrades al cuir cabellut, com els anàlisis de l'electroencefalograma (EEG) al domini del temps promitjant els potencials cerebrals relacionats a esdeveniments (ERP), i l'activitat oscil·latòria cerebral al domini temps- freqüència.
Tres estudis van mostrar el paper del gen del DAT en el control cognitiu de l'atenció, suggerint així la pertinència de la DA estriatal en la flexibilitat cognitiva. Els nostres resultats suggereixen un processament independent del context dels canvis sensorials per la reconfiguració del set de la tasca en individus amb l'al·lel de 9 repeticions de DAT (9R+) relacionats amb una major disponibilitat de dopamina estriatal. Tanmateix, aquests individus van mostrar una detecció primerenca de la rellevància per la tasca dels canvis sensorials. El gen del DAT regulava la modulació del processament de la novetat per un context emocional. Els individus 9R+ van mostrar una resposta cerebral més gran als estimuls novedosos.
Dos estudis van mostrar el paper de la interacció dels gens de la COMT i del DRD2 sobre processos atencionals. S'ha suggerit que els individus amb l'al·lel de COMT Val i l'al·lel de DRD2 A1 (A1+) i COMT Met sense l'al·lel de DRD2 A1 (A1-) mostren una interacció equilibrada de dopamina prefrontal i estriatal. Aquests grups van mostrar distracció conductual, mentre que els individus ValA1- i els individus MetA1+ no van ser distrets per sons nous en un paradigma de distracció visual auditiu. Els grups, tanmateix, no-distrets resultaven processar esdeveniments nous a través de la restauracio d'activitat neuronal a 40 Hz. A més, aquells amb una interacció equilibrada semblaven tornar a configurar la informació de la tasca quan era necessari, mentre que aquells amb dopamina PFC o estriatal extremes tornarien a configurar el set de la tasca després de cada canvi sensorial.
Els resultats dels estudis de la tesi proporcionen una evidència del paper rellevant dels gens de la COMT, el DAT1 i el DRD2 en processos cognitius, i ajuden a entendre els dèficits cognitius associats a la disregulació de la dopamina en trastorns psiquiàtrics.
Pomè, Antonella. "Attentional mechanisms and number representation." Doctoral thesis, 2020. http://hdl.handle.net/2158/1206037.
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