Academic literature on the topic 'Atropisomerismo'

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Journal articles on the topic "Atropisomerismo"

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Clayden, Jonathan. "Atropisomerism." Tetrahedron 60, no. 20 (May 2004): 4335. http://dx.doi.org/10.1016/j.tet.2004.03.002.

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Czarnocki, Zbigniew, and Piotr Pomarański. "Arylpyridines: A Review from Selective Synthesis to Atropisomerism." Synthesis 51, no. 03 (December 14, 2018): 587–611. http://dx.doi.org/10.1055/s-0037-1611365.

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Multiply arylated heterocycles are interesting structures with highly useful functions and fascinating optoelectronic and biological properties. Pyridines are an important class of compounds, playing a role in various fields of chemistry. When the pyridine ring is connected to other aromatic systems, novel stereochemical outcomes may arise. This work summarizes different methodologies applied for the synthesis of substituted arylpyridine derivatives and summarizes stereochemical phenomena resulting from atropisomerism present in certain arylated pyridines.1 Introduction2 Arylpyridines Containing meta- and para-Substituted Phenyl Groups2.1 Arylpyridine Derivatives as Amphetamine Analogues Markers2.2 Site-Selective Synthesis of Arylpyridines3 Atropisomerism in Arylpyridines Containing ortho-Substituted Phenyl Groups3.1 Synthesis of Arylpyridines Containing ortho-Substituted Phenyl Groups3.2 Other Methods for the Preparation of Arylated Pyridines4 Fully Substituted Pyridine Derivatives4.1 Site-Selective Synthesis of Fully Arylated Pyridines4.3 Atropisomerism in Densely Substituted Arylpyridines Containing ortho-Substituted Phenyl Groups5 Enantioselective Synthesis of Arylpyridine Derivatives6 Conclusion
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Siegel, Jay. "Prologue: Atropisomerism." Synlett 29, no. 16 (September 21, 2018): 2122–25. http://dx.doi.org/10.1055/s-0037-1610908.

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Jay S. Siegel received his Ph.D. from Princeton (1985), was a Swiss Universities Fellow at ETH Zurich (1983-4), and NSF–CNRS postdoctoral fellow at the University of Louis Pasteur in Strasbourg (1985-6). He began as Assistant Professor of Chemistry (1986) at UCSD, was promoted to Associate Professor (1992) and Full Professor (1996). In 2003, he was appointed as Professor and co-director of the Organic chemistry institute of the University of Zurich (UZH) and Director of its laboratory for process chemistry research (LPF). He served as Dean of Studies and Head of the Research Council for the Faculty of Sciences at UZH. He moved to Tianjin University in 2013 as dean, and joined the Schools of Pharmaceutical and Life Sciences into a new Health Science Platform. His research is in the area of Stereochemistry and Physical Organic Chemistry.
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Fordyce, Euan A. F., S. Fraser Hunt, Damien Crepin, Stuart T. Onions, Guillaume F. Parra, Chris J. Sleigh, John King-Underwood, Harry Finch, and John Murray. "Conformationally restricted benzothienoazepine respiratory syncytial virus inhibitors: their synthesis, structural analysis and biological activities." MedChemComm 9, no. 3 (2018): 583–89. http://dx.doi.org/10.1039/c8md00033f.

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Birepinte, Mélodie, Frédéric Robert, Sandra Pinet, Laurent Chabaud, and Mathieu Pucheault. "Non-biaryl atropisomerism at the C–B bond in sterically hindered aminoarylboranes." Organic & Biomolecular Chemistry 18, no. 16 (2020): 3007–11. http://dx.doi.org/10.1039/d0ob00421a.

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Bischetti, Martina, Giuseppe Pomarico, Sara Nardis, Federica Mandoj, Daniel O. Cicero, and Roberto Paolesse. "5,10,15-Triarylcorrole atropisomerism." Journal of Porphyrins and Phthalocyanines 24, no. 01n03 (January 2020): 153–60. http://dx.doi.org/10.1142/s1088424619500706.

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A series of 5,10,15-triarylcorroles has been prepared, with the meso-aryl rings functionalized with different substituents to investigate their influence on the aryl ring rotation with respect to the corrole plane. The study has been carried out by different NMR techniques, allowing the complete assignment of the 1H NMR spectra and giving insights on the kinetic and thermodynamic factors driving the atropisomerism in triarylcorrole derivatives.
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Siegel, Jay. "Cluster Preface: Atropisomerism." Synlett 29, no. 16 (September 21, 2018): 2120–21. http://dx.doi.org/10.1055/s-0037-1610998.

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Jay S. Siegel received his Ph.D. from Princeton (1985), was a Swiss Universities Fellow at ETH Zurich (1983-4), and NSF–CNRS postdoctoral fellow at the University of Louis Pasteur in Strasbourg (1985-6). He began as Assistant Professor of Chemistry (1986) at UCSD, was promoted to Associate Professor (1992) and Full Professor (1996). In 2003, he was appointed as Professor and co-director of the Organic chemistry institute of the University of Zurich (UZH) and Director of its laboratory for process chemistry research (LPF). He served as Dean of Studies and Head of the Research Council for the Faculty of Sciences at UZH. He moved to Tianjin University in 2013 as dean and joined the Schools of Pharmaceutical and Life Sciences into a new Health Science Platform. His research is in the area of Stereochemistry and Physical Organic Chemistry.
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Boiadjiev, Stefan E., and David A. Lightner. "Atropisomerism in monopyrroles." Tetrahedron: Asymmetry 13, no. 16 (August 2002): 1721–32. http://dx.doi.org/10.1016/s0957-4166(02)00481-0.

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Ciogli, A., S. Vivek Kumar, M. Mancinelli, A. Mazzanti, S. Perumal, C. Severi, and C. Villani. "Atropisomerism in 3-arylthiazolidine-2-thiones. A combined dynamic NMR and dynamic HPLC study." Organic & Biomolecular Chemistry 14, no. 47 (2016): 11137–47. http://dx.doi.org/10.1039/c6ob02145j.

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Köster, Roland, Günther Seidel, Susanna Kerschl, and Bernd Wrackmeyer. "Atropisomerism in Boron-Nitrogen Heterocycles/Atropisomerism in Boron-Nitrogen Heterocycles." Zeitschrift für Naturforschung B 42, no. 2 (February 1, 1987): 191–94. http://dx.doi.org/10.1515/znb-1987-0212.

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Abstract Atropisomerism owing to hindered rotation about the N-aryl bond is observed in 4,5-diethyl-2,2,3-trimethyl-1-(o-trifluormethyl)phenyl-2,5-dihydro-1H-1,2,5-azasila-(2) and -azastanna-boroles (5). The compounds 2 and 5 are characterized by elemental analysis, mass spectra and 1H, 11B, 13 C, 29Si and119Sn NMR. The ortho-trifluoromethyl group serves as an additional NMR spectroscopic probe because of “through space” 19F-1H and 19F-13C spin spin coupling. Compound 5 is the first derivative of a 2,5-dihydro-1H-1,2,5-azastannaborol.
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Dissertations / Theses on the topic "Atropisomerismo"

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Fontanive, Luca. "Nanoscale intercation for higher efficiency of contrast media." Doctoral thesis, Università degli studi di Trieste, 2011. http://hdl.handle.net/10077/4476.

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2009/2010
Iopamidolo, Iomeprolo e Iopromide sono Mezzi di Contrasto Iodinati Non-ionici (MCIN) usati in urografia e angiografia come soluzioni concentrate. I dati relativi ai MCIN presenti in letteratura mostrano un’abbondanza di informazioni cliniche ma una carenza di dati riguardanti le loro caratteristiche chimico-fisiche. L’efficenza di questi composti in ambito medico è dovuta alla combinazione di tali proprietà. Risulta quindi necessario uno studio relativo ai dettagli molecolari per chiarire i contributi di ogni gruppo funzionale del sistema che determinano le differenze in termini di comportamento chimico-fisico. Le soluzioni concentrate di MCIN sono caratterizzate da bassi valori di viscosità e osmolalità dovuti all’autoassemblamento del sistema che genera aggregati nanostrutturati solubili in soluzione acquosa. Da queste considerazioni, questo lavoro di ricerca si è focalizzata su tecniche spettroscopiche, termodinamiche e di simulazioni di dinamica molecolare per indagare il fenomeno dell’associazione, sia in funzione della temperatura che della concentrazione, relazionato alle interazioni intermolecolari che spesso sono la principale causa della stabilità delle soluzioni concentrate di MCIN. Questi composti possiedono una struttura molecolare relativamente semplice, ma sono sistemi complessi in quanto soggetti all’atropisomerismo che causa la coesistenza di isomeri strutturali (atropisomeri) in soluzione, quindi di diverse geometrie di interazione soluto-soluto. Il primo approccio sperimentale è stata la caratterizazione molecolare attraverso la spettroscopia NMR per determinare gli equilibri conformazionali in termini di percentuali di popolazione in soluzione. Studi termodinamici hanno permesso di classificare Iopamidolo, Iomeprolo e Iopromide in base alle loro caratteristiche idrofiliche ed idrofobiche nei confronti delle molecole di acqua. Parallelamente sono state realizzate simulazioni di dinamica molecolare per ottenere informazioni riguardo la sfera di idratazione (confrontate con i dati termodinamici da letteratura) e sul processo di associazione che è stato studiato in funzione della temperatura sia con la spettroscopia NMR che con quella Brillouin. Ulteriori informazioni sulle interazioni intermolecolari e sull’atropisomerismo sono state ottenute analizzando anche lo stato solido dello Iopamidolo e dello Iomeprolo (sia sui vetri che sui cristalli) tramite tecniche spettroscopiche, calorimetriche e diffrattometriche i cui risultati hanno mostrato analogie in termini di interazioni intermolecolari fra le catene laterali. Inoltre, studi in funzione della temperatura hanno mostrato alcune transizioni solido-solido. L’accumulo di dati sperimentali relativi alla calorimetria isoterma e a scansione, traiettorie di dinamica molecolare ed alle varie spettroscopie, ha permesso di estendere il quadro generale delle conoscenze delle proprietà chimico-fisiche dei MCIN.
Iopamidol, Iomeprol and Iopromide are Non-ionic Iodinated Contrast Media (NICMs) are used as concentrated solutions in x-Ray diagnostics as angiography and urography. The analysis of the current literature knowledge on NICMs shows an clear abundance of clinical diagnosis data but a lack of information on their physico-chemical properties. The success of these molecules in diagnosis is due to a combination of their properties, but a clarification of the role of structural determinants affecting the processes in concentrated solution is necessary. Thus a study of the molecular details may shed light on the differences in physico-chemical behavior. The concentrated solutions of NICMs are characterize by low viscosity and osmolality values due to the self-assembling of the system that generates soluble nano-structured aggregates in aqueous solution. Standing these considerations, the research work focused on spectroscopic, thermodynamics and MD simulation techniques to probe the association phenomenon, as a function of concentration and temperature. The interplay of the intermolecular interactions are the main reason for the stability of the concentrated solution of NICMs. Non-ionic iodinated contrast media have quite a simple molecular structure, but they show a complex behaviour due to the atropisomerism phenomenon. The coexistence of several structural isomers (atropisomers) in solution is at the basis of the different geometries of solute-solute interasctions. Thus, the first study whas been the molecular characterization of these molecules by using NMR spectroscopy to probe the conformational equilibria in terms of conformer population in solution. Thermodynamic approaches provided a classification of Iopamidol, Iomeprol and Iopromide according to their thermodynamics behaviour in terms of hydrophilic and hydrophobic interactions with water molecules. In parallel, MD simulations data were carried out to provide information about hydration shell (which were compared with experimental data from literature) and aggregation process. Similarly, the association was probed by both NMR and experimental thermodynamic data. To have more information on the nature of intermolecular interactions and atropisomerism phenomenon the solids of Iomeprol and Iopamidol (either or glasses and crystals) were analyzed by spectroscopic, calorimetric and diffractometric techniques that shown agreement in terms of intermolecular interactions among side chains. Furthemore, solid-solid transitions were detected as a function of temperature. By collecting experimental data by isothermal and scanning calorimetry, thermodynamic properties, molecular dynamics simulations and expecially by several spectroscopics methods a choerent description of the structure and dynamics of NICMs has been achieved. These results provide new knowledge on thier physico-chemical properties and allow us to interpret some anclear phenomena.
XXIII Ciclo
1980
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Yau, Chi. "Atropisomerism and the synthesis of lignans." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ62875.pdf.

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Senior, James Daniel. "Atropisomerism in biaryl sulfides and sulfones." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498670.

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The thesis describes research carried out on the synthesis and asymmetric synthesis of atropisomeric biaryl sulfides and sulfones. Chapter one describes synthetic strategies employed in the synthesis of biaryl sulfides and sulfones. A synthetic route that allowed the incorporation ortho substituents of various sizes and the effect of these substitution patterns on barriers to rotation is described. Research towards more direct routes to compounds with the required substitution pattern is then discussed. Having uncovered suitable substitution patterns to achieve atropisomerism in biaryl sulfides and sulfones chapter two goes on to describe methods attempted in the asymmetric synthesis of these compounds. The strategies described include asymmetric cross coupling, kinetic resolution and the use of sulfoxide auxiliaries for dynamic thermodynamic resolution of biaryl sulfones. The first example of an symmetric synthesis of an atropisomeric biaryl sulfone is reported. Chapter three outlines possible applications of biaryl sulfides and sulfones and the synthesis of bis-phosphines based on the biaryl sulfone background using methods described in chapter one.
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Wilson, Paul. "Reducing catalyst loadings in radical cyclisation reactions and investigating atropisomerism in enamides." Thesis, University of Warwick, 2010. http://wrap.warwick.ac.uk/34645/.

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The bulk of the work presented in this thesis represents an evolution of copper-mediated atom transfer radical cyclisation. Chapter 1 provides introduction to radical cyclisation methods and applications and is followed by the shortest results chapter that discusses the outcome of 1,4-dimethylpiperazine mediated radical cyclisation of monobromoacetamides. Cyclisation was possible but competing reduction and elimination pathways are prevalent when less reactive substrates are used. Chapters 3 and 4 focus on the evolution of copper-mediated atom transfer radical cyclisation. A number of additives were screened in the hope of achieving catalyst regeneration which would allow catalyst loadings to be reduced without loss of efficiency and negate the need for an inert atmosphere throughout the reaction. In chapter 3, AIBN was found to be the optimum additive and efficient cyclisation was possible using copper (I) (Cu(TPA)Br) and copper (II) (Cu(TPA)Br2) complexes (1 mol%) in DCM and toluene (at 50 and 110 oC respectively) suggesting AIBN could activate and reactivate the catalyst in situ. In chapter 4 an alternative, highly efficient process was developed using copper (II) in the presence of potassium borohydride in MeOH. Reaction times were significantly reduced (10-30 min) and reactions were performed at room temperature even at decreased catalyst loadings (0.1 mol%). The mechanism for the process is likely to differ from that of conventional atom transfer radical cyclisation. UV analysis of the catalyst complex and the reactions progress, compared to literature data, suggest the active catalyst could be a copper borohydride (CuBH4) complex. Finally chapter 5 compiles a structural analysis of a variety of enamides to determine the feasibility of chiral induction during 5-endo trig radical cyclisation. A number of N-cycloalkenyl and N-cyclohexenyl enamides, which share an axis of chirality about the N-C(cycloalkenyl) bond, were analysed by variable temperature NMR to determine the rate and barrier of rotation of the chiral axis. Although none of the enamides studied had barriers great enough to achieve chiral induction it was recognised that the barrier to rotation could be significantly increased if tetrasubstituted enamides were accessible. Tetrasubstituted enamides were prepared and their barriers were determined by chiral HPLC, with barriers predicted to be great enough for chiral induction. Cyclisation was attempted but to no avail with unexpected oxidation products being obtained. Despite this, a more comprehensive understanding of the enamide structure has paved the way for potential chiral induction in 5-endo trig radical cyclisation.
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Armstrong, Roland. "Catalytic asymmetric reactions employing chiral cations." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:6f38eb98-32ff-4b06-b144-100480da87dd.

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This thesis describes two new phase-transfer catalysed processes, in which asymmetry is mediated via ion-pairing with a chiral cation. In the first chapter, an enantioselective method for N functionalization of pyrroles is described and a phase-transfer catalysed approach to axial chirality via a cation-directed SNAr reaction is discussed in Chapters 3, 4 and 5.
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Perticarari, Sofia. "Atropisomeric xanthines: Synthesis, stereodynamics and absolute configuration." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/9025/.

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During the thesis period a new class of atropisomeric xanthine derivatives has been studied. We decided to focus our attention on these purine bases because of their various biological activities, that could play an important role in the discovery of new bioactive atropisomers. The synthesized compounds bear an Aryl-N chiral axis in position 1 of the xanthine scaffold, around which the rotation is prevented by the presence of bulky ortho substituents. Through a retro synthetic analysis we synthesized three atropisomeric structures bearing in position 1 of the purine scaffold respectively an o-tolyl, o-nitrophenyl and a 1-naphthyl group. The conformational studies by DFT simulations showed that the interconversion energy barrier between the two available skewed conformations is higher enough to obtain thermally stable atropisomers. After the separation of the atropisomers, the experimental energy of interconversion was investigated by means of kinetic studies following the thermal racemization process using an enantioselective HPLC column. The absolute configuration of each atropisomer was assigned by experimental ECD analysis and TD-DFT simulations of the ECD spectra.
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Birepinte, Mélodie. "Amino(organo)boranes, synthèse et propriétés." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0231.

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Ce manuscrit présente la synthèse, la réactivité et les propriétés des amino(organo)boranes. Le diisopropylaminoborane a été utilisé dans le cadre de la formation de liaisons carbone-bore. La réactivité du diisopropylaminoborane en tant qu’agent de borylation a d’abord été mise à profit pour l’hydroboration des alcynes catalysée par le réactif de Schwartz. Une grande variété d’alcénylaminoboranes, -boronates et -diazaborolanes a ainsi été synthétisée. Leur transformation stéréosélective en bromoalcènes Z et E a également été optimisée. La borylation des alcynes vrais via un procédé tandem de déshydrogénation / couplage déshydrogénant a permis l’accès à une grande variété d’alcynylaminoboranes. Enfin, les différentes réactivités des aminoboranes ont été mises à profit dans la préparation d’acides boriniques comportant une fonction phosphine, ainsi que d’ une nouvelle classe de dérivés du bore chiraux par atropoisomérie autour de la liaison C-B. Ces aminoarylboranes chiraux ont été caractérisés par séparation des énantiomères complétée d’études spectroscopiques et de racémisation
This manuscript presents the synthesis, reactivity and properties of amino(organo)boranes. The diisopropylaminoborane has been used for the formation of carbon-boron bonds. Its reactivity as a borylating agent was first explored for the hydroboration of alkynes catalyzed by Schwartz reageant. A large variety of alkenylaminoboranes, -boronates and -diazaborolanes was thus synthesized. Their stereoselective transformation into E and Z bromoalkenes was also optimized. The borylation of terminal alkynes via a tandem process of dehydrogenation/ dehydrogenative coupling allowed the access to a large scope of alkynylaminoboranes. Finally, the different reactivities of aminoboranes were used for the preparation of borinic acids bearing a phosphine group but also of a new class of chiral boron derivatives via a C-B atropisomerism. These chiral aminoarylboranes were fully characterized after separating the enantiomers and running spectroscopic analyses and racemization studies
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Augros, David. "Synthèses de biaryles atropoenrichis et de biphénylènes via des arynes substitués." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAF040/document.

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Les travaux présentés dans ce manuscrit ont eu pour but d’étudier le « couplage aryne », une technique de synthèse qui produit des biaryles sans l’intervention de métaux de transition, grâce à la réaction entre deux intermédiaires réactionnels générés in situ : un aryllithien nucléophile et un aryne électrophile. Les travaux réalisés ont consisté en l’optimisation de la version diastéréosélective du couplage, ensuite appliquée à la synthèse formelle de la (-)-stéganacine. Dans un second temps, les premières études sur la version énantiosélective du couplage ont été réalisées, en introduisant des ligands chiraux à la réaction et en évaluant l’influence de différents paramètres réactionnels. Les premiers excès énantiomériques ont ainsi été obtenus, parfois accompagnés de la formation de divers sous-produits, parmi lesquels des dérivés de biphénylène. Devant l’intérêt que représentent ces composés, une partie des travaux a été consacrée à leur synthèse par dimérisation des arynes
This work consisted in the study of the “aryne coupling”, a transition-metal free process to access biaryl moieties, which involves the reaction between two in situ generated intermediates: a nucleophilic aryllithium derivative and an electrophilic aryne. This work resided in the optimization of the atropoenantioselective version of the aryne coupling and its application to the formal synthesis of (-)-steganacin. We then moved to the atropoenantioselective version of the reaction, by introducing chiral ligands in the reaction mixture, which aim was to coordinate the aryllithium species and to transfer their chiral information to the biaryl axis. After optimization of various reaction parameters, some enantiomeric excesses were obtained as well as various side products in some cases, among which biphenylene derivatives. According to the potential applications of these compounds, another part of this work was dedicated to their synthesis by means of aryne dimerization reactions
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Böhnisch, Torben. "C2-Symmetric Pyrazole-Bridged Ligands and Their Application in Asymmetric Transition-Metal Catalysis." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://hdl.handle.net/11858/00-1735-0000-0028-876A-6.

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Rebouças, Júlio Santos. "Exploring and exploiting Ruthenium-porphyrin complexes : functionalization, atropisomerism, small-molecule recognition, catalysis, and biological implications." Thesis, 2006. http://hdl.handle.net/2429/18618.

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This thesis represents a contribution to advances in ruthenium-porphyrin chemistry. The synthesis of Ru(carbonyl) porphyrins via a new metallation strategy using hexakis(N,N-dimethylformamide)ruthenium(III) triflate is examined in detail, covering a broad range of porphyrins. Mechanistic insights, advantages, and limitations of the methodology are also addressed. The method is also shown to be of value in the preparation of other related Ru macrocyclic complexes, such as those of tetradentate Schiff-bases. The direct β-functionalization of Ru(carbonyl) porphyrins is explored, as a convenient alternative for the Ru-metallation of β-functionalized free-bases. Specifically, protocols for β-octachlorination, β-octabromination, and β-mononitration are discussed. Electrochemical studies on Ru(carbonyl) porphyrins are explored as probes for investigating some structural aspects of these complexes. It is proposed that Ru complexation hinders distortion of the porphyrin ring from a planar configuration, and examination of literature crystallographic data is used to rationalize such a "Ru effect". The effect has direct consequences in hampering aryl-ring rotation in meso-tetraarylporphyrins, and this is exploited to yield the first examples of atropisomerism in non-ortho-substituted porphyrins containing non-bulky meta-substituents. Ruthenium porphyrins are used as models for studying several aspects of heme-proteins that contain S-donor ligands proximal to the heme moiety. The coordination capability of the Ru(porphyrin) moiety is explored for preparation of adducts with thiols, organic disulfides, and trisulfides. The reactions between Ru porphyrins and H₂S are also discussed. The steric and electronic effects involved in small-molecule recognition by simple metalloporphyrins using Ru porphyrins and thiols as probes are examined thoroughly. The model proposed to describe thiol coordination is also extended to another coordination system, that with primary amines, and represents a successful, general attempt to depict quantitatively the non-bonding interactions between axial ligands and the porphyrin plane. The implications of the findings within the thiol--Ru-porphyrin systems to the evolution of heme-thiol(ate) proteins are contemplated, and the application of the amine--Ru-porphyrin models to examine the interactions between primary amines and heme-proteins is demonstrated. The first studies on investigation of the O₂-oxidation of thiols catalyzed by Ru porphyrins are presented, together with a tentative mechanism that accommodates generally the kinetic and spectroscopic data. The ability of Ru porphyrins to perform O₂-oxidative N-dealkylations of tertiary amines, which is a classical cytochrome P450-catalyzed reaction, is also demonstrated. Finally, a simple (phosphine-free) RuCl₃-based, H₂-hydrogenation method is shown to be useful for the preparation of mesoporphyrin dimethyl ester.
Science, Faculty of
Chemistry, Department of
Graduate
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Books on the topic "Atropisomerismo"

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Westlund, Neil Edward. Atropisomerism in hindered tertiary amides. Manchester: University of Manchester, 1996.

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Lassaletta, José M. Atropisomerism and Axial Chirality. WORLD SCIENTIFIC (EUROPE), 2018. http://dx.doi.org/10.1142/q0192.

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Book chapters on the topic "Atropisomerismo"

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Ōki, Michinori. "Recent Advances in Atropisomerism." In Topics in Stereochemistry, 1–81. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470147238.ch1.

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Cesàro, Attilio, Barbara Bellich, Giovanna Giannini, and Alessandro Maiocchi. "Conformational Disorder and Atropisomerism in Pharmaceutical Compounds." In Disordered Pharmaceutical Materials, 161–82. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527652693.ch6.

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Dreikorn, Barry A., Glen P. Jourdan, and Harold R. Hall. "Influence of Atropisomerism on the Fungicidal Activity of a Series of Thioalkylphenylalanines." In ACS Symposium Series, 575–88. Washington, DC: American Chemical Society, 1991. http://dx.doi.org/10.1021/bk-1991-0443.ch046.

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Joshi, Gaurav, Manpreet Kaur, and Raj Kumar. "Dynamic Axial Chirality in Drug Design and Discovery: Introduction to Atropisomerism, Classification, Significance, Recent Trends and Challenges." In Drug Discovery and Development, 103–24. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-5534-3_4.

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Ros, Abel, Pedro Ramírez-López, Rosario Fernández, and José María Lassaletta. "Asymmetric Synthesis of Axially Chiral Biaryls and Heterobiaryls." In Atropisomerism and Axial Chirality, 1–97. WORLD SCIENTIFIC (EUROPE), 2019. http://dx.doi.org/10.1142/9781786346469_0001.

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Kondoh, Azusa, and Masahiro Terada. "Applications of Axially Chiral Organocatalysts." In Atropisomerism and Axial Chirality, 99–147. WORLD SCIENTIFIC (EUROPE), 2019. http://dx.doi.org/10.1142/9781786346469_0002.

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Yurino, Taiga, and Takeshi Ohkuma. "Axially Chiral P,P-Ligands for Asymmetric Metal-Catalyzed Reactions." In Atropisomerism and Axial Chirality, 149–247. WORLD SCIENTIFIC (EUROPE), 2019. http://dx.doi.org/10.1142/9781786346469_0003.

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Gualtierotti, Jean-Baptiste, Valentín Hornillos, and Ben L. Feringa. "Axially Chiral Monodentate Phosphorus Ligands for Asymmetric Metal-Catalyzed Reactions." In Atropisomerism and Axial Chirality, 249–377. WORLD SCIENTIFIC (EUROPE), 2019. http://dx.doi.org/10.1142/9781786346469_0004.

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Rokade, Balaji V., and Patrick J. Guiry. "Axially Chiral P,X-Ligands (X = N, O, and S) for Asymmetric Metal-Catalyzed Reactions." In Atropisomerism and Axial Chirality, 379–445. WORLD SCIENTIFIC (EUROPE), 2019. http://dx.doi.org/10.1142/9781786346469_0005.

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Ying, Jun, and Lin Pu. "Axially Chiral X,X-Ligands (X = N, O) for Asymmetric Metal-Catalyzed Reactions." In Atropisomerism and Axial Chirality, 447–88. WORLD SCIENTIFIC (EUROPE), 2019. http://dx.doi.org/10.1142/9781786346469_0006.

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Conference papers on the topic "Atropisomerismo"

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Cardoso, Flávio Sêga Pereira, and Aaron Aponick. "A New Approach to Atropisomerism." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013816154041.

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