Journal articles on the topic 'ATAD models'
To see the other types of publications on this topic, follow the link: ATAD models.
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'ATAD models.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Öner, Cihat. "Comparative Analysis of the General Anti-Abuse Rule of the Anti-Tax Avoidance Directive: An Effective Tool to Tackle Tax Avoidance?" EC Tax Review 29, Issue 1 (March 1, 2020): 38–52. http://dx.doi.org/10.54648/ecta2020005.
Full textAbstract:
The primary aim of this article is to question whether the general anti-abuse rule (GAAR) of Anti-Tax Avoidance Directive (ATAD) is an effective tool to tackle tax avoidance. By using a comparative technique as a method, other directives that include a GAAR will be analysed as a companion to the ATAD to identify whether there is a common understanding of the concept of abuse of tax laws within the EU legal order. Then the general consequences of the application of the GAAR of the ATAD will be exposed. The difficulties which could be encountered in the application procedure will be explained around some potential scenarios, based on simple models developed by the author. Tax Avoidance, Abusive Tax Practices, Artificial/Genuine Arrangement(s), Main Purpose(s) Test, Tax Advantage, General Anti-abuse Rule(s) (GAARs), Anti-Tax Avoidance Directive (ATAD), Interest-Royalties Directive, Merger Directive, Parent- Subsidiary Directive.
2
Bin Mahmood, Syed Usman, Makoto Mori, Arnar Geirsson, John A. Elefteriades, and Abeel A. Mangi. "Acute Type A Aortic Dissection Surgery Performed by Aortic Specialists Improves 2-Year Outcomes." AORTA 07, no. 01 (February 2019): 001–6. http://dx.doi.org/10.1055/s-0039-1687904.
Full textAbstract:
Objective In patients presenting with acute Type A aortic dissections (ATADs), the authors sought to evaluate whether emergent aortic operations performed by cardiac surgeons with different level of aortic surgery experience can impact perioperative outcomes and survival. Methods A single-center review of 102 patients who underwent aortic surgeries for ATAD was conducted. The cohort was divided into those operated on by aortic specialists (AS:3 surgeons) and non-AS (5 surgeons). Multivariable logistic regression and Cox proportional hazard models were fitted to evaluate associations between the surgeon experience, perioperative outcomes, and survival, respectively. Results Of 102 patients, 60 were operated on by AS and 42 were operated on by non-AS. Overall 30-day mortality was 11 (10.8%) with 4 (6.6%) perioperative deaths in the AS group and 7 (16.6%) among the non-AS group (p = 0.2). AS performed a significantly higher number of root replacement procedures (41.6% vs. 23.8%, respectively, p = 0.049) and employed more frequent adjunct cerebral perfusion during circulatory arrest (p = 0.003). Survival analysis indicated AS status was an independent predictor of improved 2-year survival (hazard ratio: 0.37, 95% confidence interval: 0.15–0.92, p = 0.03). Conclusion Operation by AS for ATAD was associated with reduced adjusted risk of 2-year mortality. This adds support for establishing thoracic aortic emergency call teams staffed by AS.
3
Kardachaki, Alexia. "The Impact of European Union Law on the Possibilities of European Union Member States to Adapt International Tax Rules to the Business Models of Multinational Enterprises." Intertax 44, Issue 10 (October 1, 2016): 746–54. http://dx.doi.org/10.54648/taxi2016064.
Full textAbstract:
European Union (EU) law has played a key role in enforcing the EU base erosion and profit shifting (BEPS) agenda, while also introducing limits to the application thereof. The European Commission (EC) sees a clear link between aggressive tax planning and competition law. Against this background, EU State aid law has been employed to challenge the business models of multinational enterprises. At present there are a number of opened cases, where a decision either by the EC or the General Court of the EU is pending. These cases deal with the application of EU State aid law on inter alia tax regimes (e.g. exemption of interest and royalty payments), transfer pricing, and the misapplication of law. The approach the EC is taking in those cases, especially in matters of competence, raises a number of questions, which can only be addressed in a definitive manner by the EU Courts. Similar issues may arise in the field of positive harmonization through the recently adopted Anti-Tax Avoidance Directive (ATAD). For instance, given that a general anti-abuse rule has been included in Article 6 ATAD and has therefore become EU law, the EC and the EU Courts are competent to decide whether it should be applied in certain situations, and whether non-application thereof may amount to unlawful State aid. However, EU free movement law should be respected by Member States when implementing anti-BEPs measures. Accordingly, so far, the limitation on benefits clause contained in double tax treaties has been challenged by the EC, while the compatibility of the anti-avoidance rules against hybrid mismatches with EU free movement law is questionable.
4
Akoğlan Kozak, Meryem, and Birgül Aydın. "Grönroos Hizmet Kalitesi Modeli: Otelcilik Alanyazını Üzerinden Bir Değerlendirme." Anatolia: Turizm Araştırmaları Dergisi 29, no. 2 (November 27, 2018): 175–84. http://dx.doi.org/10.17123/atad.488199.
Full text
5
BOZKURT, Kurtuluş, Aytaç PEKMEZCİ, and Hatice ARMUTCUOGLU TEKİN. "Forecasting Tourism Demand By Box-Jenkins Method: The Case of Türkiye." Anatolia: Turizm Araştırmaları Dergisi 33, no. 2 - Ön Yayımdaki Makaleler (January 1, 2022): 77–86. http://dx.doi.org/10.17123/atad.1087573.
Full textAbstract:
Türkiye’nin en önemli gelir kaynaklarından biri olan turizm sektöründe gelecek dönemlerdeki olası turizm talebinin belirlenmesi; kaynakların dağıtılması ve planlanması, doğru fiyat politikalarının tespit edilmesi ve uygun pazarlama tekniklerinin seçilmesi açısından önem arz etmektedir. Bu nedenle, bu çalışmada Ekim 2021 ve Eylül 2022 (2021:10 – 2022:09) tarihlerindeki Türkiye’ye yönelik turizm talebinin tahmin edilmesi amaçlanmıştır. Bu bağlamda turizm talebinin tahmin edilmesinde vekil değişken olarak 1990:01 - 2021:09 zaman aralığında Türkiye’ye gelen turist sayıları verileri kullanılmıştır. Belirtilen dönemde gerçekleşmesi beklenen turizm talebinin tahmin edilmesinde Box-Jenkins yöntemi altında ele alınan ARIMA (entegre otoregresif hareketli ortalama modeli) ve SARIMA (mevsimsel entegre otoregresif hareketli ortalama modeli) modelleri uygulanmıştır. Çalışmanın sonucunda en iyi uyum gösteren modelin, SARIMA (2,1,2)(2,1,0) modeli olduğu belirlenmiştir. Çalışmada ayrıca gelecek 12 aya yönelik öngörü yapılmıştır.
6
ÖCEK, Cemile, Fatma Senem BEYAZ, and Erdinç KARADENİZ. "The Financial Failure Risks of Restaurant Chaiıns and The Impact of Covıd-19." Anatolia: Turizm Araştırmaları Dergisi 33, no. 2 - Ön Yayımdaki Makaleler (January 1, 2022): 65–76. http://dx.doi.org/10.17123/atad.1040782.
Full textAbstract:
Bu araştırmanın amacı marka değeri en yüksek restoran zincirlerinin finansal başarısızlık risk düzeylerini incelemek ve Covid-19 salgınının finansal başarısızlık riski üzerindeki etkisini ortaya koymaktır. Bu amaçla Brand Finance 2020 sıralamasına göre marka değeri en yüksek 17 restoran zincirinin, 2016-2020 yılları arasında finansal başarısızlık riskleri Altman Z Skor, Altman Z’ Skor, Altman Z’’ Skor, Springate, Fulmer ve Ohlson modelleriyle ölçülmüştür. Analiz sonucunda finansal başarısızlık riski taşıyan restoran sayısının tüm modellerde geçmişten günümüze yaklaştıkça artış eğiliminde olduğu belirlenmiştir. Bununla birlikte Covid-19 salgını öncesi (2016-2019) ve Covid-19 salgını dönemi (2020) arasındaki finansal başarısızlık risk skorları bağlamında istatistiksel olarak anlamlı bir fark olup olmadığı Wilcoxon İşaretli Sıra Testi ile test edilmiştir. Elde edilen sonuca göre Ohlson modeli dışındaki tüm modellerde Covid-19 salgını öncesi ve salgın dönemi arasında finansal başarısızlık değerleri bağlamında istatistiksel olarak anlamlı farklılık saptanmıştır.
7
Setiawan, Andrew, and Supriono Supriono. "PROTOTIPE KENDALI MODEL ATAP BERSIRIP OTOMATIS TERMONITORING UNTUK TEMPAT PENGERINGAN BERBASIS SMS GATEWAY DENGAN MODUL GSM(GPRS) SIM800L." Transmisi 22, no. 3 (August 17, 2020): 88–95. http://dx.doi.org/10.14710/transmisi.22.3.88-95.
Full textAbstract:
Permasalahan utama dari proses penjemuran hasil panen pertanian dan proses permindahan hasil panen dari penjemuran ke tempat penyimpanan adalah kondisi cuaca. Kemajuan teknologi nirkabel (wireless) sangat mendukung sebagai sarana monitoring pada proses penjemuran hasil panen pertanian, salah satunya adalah teknologi GSM (Global System for Mobile Communications) yang murah dengan jangkauan luas serta media komunikasi dan sarana informasi yang real-time. Penelitian ini bertujuan merancang suatu sistem kendali model atap bersirip otomatis termonitor melalui handphone yang bisa mengendalikan buka atau tutup atap secara manual, dapat juga bekerja secara otomatis terus-menerus dengan membaca parameter-parameter kondisi lingkungan seperti cuaca hujan atau tidak, cuaca cerah tersinari matahari maupun suhu ruang yang disesuaikan >29o. Sistem dirancang menggunakan sensor hujan ( Weather Sensitivity Module ), sensor suhu DHT11, dan sensor cahaya LDR (Light Dependant Resistor) serta motor servo sebagai aktuator dengan menggunakan Arduino sebagai unit pengendali sistem. Sistem dirancang dengan kemampuan untuk menyesuaikan arah sinar matahari (tracking) dengan posisi sirip atap antara 110o,130o,145o dan 175o guna memaksimalkan panas sinar matahari pada proses penjemuran yang dilengkapi dengan modul GSM SIM800L untuk proses monitoring dan kontrol jarak jauh. Keberhasilan penelitian ini sangat bermanfaat di bidang pertanian khususnya penerapan teknologi hasil pertanian.
8
Syafriani, Dewi. "PENERAPAN MODEL PEMBELAJARAN UNTUK MENUMBUHKAN KREATIVITAS DAN KEMANDIRIAN SISWA PADA PELAJARAN KIMIA DI SEKOLAH MENENGAH ATAS." SCHOOL EDUCATION JOURNAL PGSD FIP UNIMED 4, no. 2 (December 30, 2015): 60–74. http://dx.doi.org/10.24114/sejpgsd.v4i2.3621.
Full text
9
Levine, Carolyn B., and Richard C. Sansing. "The Private Foundation Minimum Distribution Requirement and Public Policy." Journal of the American Taxation Association 36, no. 1 (September 1, 2013): 165–80. http://dx.doi.org/10.2308/atax-50619.
Full textAbstract:
ABSTRACT This study examines the public policy rationale for the minimum distribution requirement that requires private foundations to spend at least 5 percent of their assets on charitable purposes. The study explicitly models an objective function that the government tries to maximize and a population of heterogeneous contributors that care about both distributions to charity and assets under their control. An increase in the minimum distribution requirement increases the rate of charitable distributions from some foundations, but deters other contributors from forming foundations. The level of the minimum distribution requirement reflects a trade-off between these two effects.
10
Cahyadi Wiguna, Made Oka. "HAK KOMUNAL ATAS TANAH SEBAGAI HAK ATAS TANAH DESA PAKRAMAN DI BALI." VYAVAHARA DUTA 13, no. 2 (January 14, 2019): 9. http://dx.doi.org/10.25078/vd.v13i2.682.
Full textAbstract:
The government has indeed provided legal protection and certainty to indigenous peoples regarding their ulayat lands, through a Ministerial Regulation. However, it needs to be studied more deeply about the concept of communal rights to land and Pakraman village as the subject of communal rights holders on land. Communal rights to land are conceptualized as models of land rights that have just been raised in the national land law system. The consequence is that indigenous and tribal peoples as communal rights holders are authorized to use and benefit from their communal land. Pakraman village qualifies as a subject of communal rights to land because Pakraman village in Bali is classified into the community of the community, has a system of customary government referred to as the traditional prajuru led by a customary village leader. Then Pakraman village has a legal area called the Palemahan Pakraman village. As an instrument that regulates the life and social interaction of the community, awig-awig is the customary law of the community in a Pakraman village in Bali.
11
Gosukonda, Ramana, Ajit K. Mahapatra, Daniel Ekefre, and Mark Latimore. "Prediction of Thermal Properties of Sweet Sorghum Bagasse as a Function of Moisture Content Using Artificial Neural Networks and Regression Models." Acta Technologica Agriculturae 20, no. 2 (June 27, 2017): 29–35. http://dx.doi.org/10.1515/ata-2017-0006.
Full textAbstract:
Abstract Artificial neural networks (ANN) and traditional regression models were developed for prediction of thermal properties of sweet sorghum bagasse as a function of moisture content and room temperature. Predictions were made for three thermal properties: 1) thermal conductivity, 2) volumetric specific heat, and 3) thermal diffusivity. Each thermal property had five levels of moisture content (8.52%, 12.93%, 18.94%, 24.63%, and 28.62%, w. b.) and room temperature as inputs. Data were sub-partitioned for training, testing, and validation of models. Backpropagation (BP) and Kalman Filter (KF) learning algorithms were employed to develop nonparametric models between input and output data sets. Statistical indices including correlation coefficient (R) between actual and predicted outputs were produced for selecting the suitable models. Prediction plots for thermal properties indicated that the ANN models had better accuracy from unseen patterns as compared to regression models. In general, ANN models were able to strongly generalize and interpolate unseen patterns within the domain of training.
12
Tóth, János, and István Farkas. "Mathematical Modelling of Solar Thermal Collectors and Storages." Acta Technologica Agriculturae 22, no. 4 (December 1, 2019): 128–33. http://dx.doi.org/10.2478/ata-2019-0023.
Full textAbstract:
Abstract Block-oriented modelling is a powerful tool in system design. The models developed this way can be used to study various systems, such as solar thermal systems. In the work presented, main goal is to compare different mathematical models of solar thermal devices. The difference in accuracy of such models in respect to the possibilities of a hardware-in-the-loop simulation will be discussed. Two models of solar thermal collectors will be compared and used in a system containing two different heat storages in order to study the behaviour of these models. The tests were carried out in a Simulink based block-oriented environment called SimSolar.
13
Hansen, Kristine, and Joyce Adams. "Teaching Writing in the Social Sciences: A Comparison and Critique of Three Models." Across the Disciplines 7, no. 1 (2010): 1–17. http://dx.doi.org/10.37514/atd-j.2010.7.1.04.
Full text
14
Inskyi, Roman Kuzm, Stefan Kovalishyn, Yurij Kovalchyk, and Roman Sheremeta. "Mathematical Models of Geometric Sizes of Cereal Crops’ Seeds as Dependent Random Variables." Acta Technologica Agriculturae 21, no. 3 (September 1, 2018): 100–104. http://dx.doi.org/10.2478/ata-2018-0018.
Full textAbstract:
Abstract Dimensions of 100 randomly selected wheat seeds of the Smuglyanka variety, rye seeds of the Puhovchanka variety and barley seeds of the Pejas variety were determined by measuring their length (l), width (b) and thickness (h). Results of the measurements were processed by the methods of mathematical statistics; parameters of distributions of individual sizes as random variables were calculated. On the basis of values of variation coefficient, the density function of normal distribution (Gaussian distribution) was taken as a model of individual sizes of seeds. Models of two-dimensional distributions of seed sizes as independent random variables were presented. Correlation coefficients between geometric sizes of seeds were calculated. Obtained values of the correlation coefficients indicate that the geometric sizes of seeds should be considered as dependent random variables. Mathematical models of geometric sizes of studied cereal crops’ seeds as dependent random variables in the form of density functions of their normal distribution were proposed. By values of the sums of squared deviations as a fitting criterion, it was established that the mathematical models of geometric sizes of seeds as dependent random variables in the form of density functions of their normal distribution provide better data approximation than the mathematical models of geometric sizes of some cereal crops’ seeds as independent random variables.
15
Widodo, Puput, and Ria Lumintuarso. "Pengembangan model permainan tradisional untuk membangun karakter pada siswa SD kelas atas." Jurnal Keolahragaan 5, no. 2 (September 23, 2017): 183. http://dx.doi.org/10.21831/jk.v5i2.7215.
Full textAbstract:
Penelitian ini mengadaptasi penelitian dan pengembangan pendidikan model Borg & Gall dengan menyederhanakan menjadi 2 tahapan sebagai berikut (1) tahap pra-pengembangan, tahapan ini meliputi (a) kajian literatur dan penelitian relevan dan (b) studi lapangan, (2) tahap pengembangan, tahapan ini meliputi (a) penyusunan draf, (b) validasi ahli, (c) uji coba model skala kecil, (d) uji coba model skala besar, dan (e) produk akhir. Uji coba skala kecil dilakukan terhadap 30 anak kelas atas SDN Aditirto Pejagoan Kebumen, Provinsi Jawa Tengah. Uji coba skala besar dilakukan terhadap 130 anak kelas atas dari SD Negeri 1 Karangpoh, 26 siswa SD Negeri 1 Logede, 22 siswa SD Negeri 4 Pejagoan, 24 siswa SD Negeri 1 Kebulusan, dan 30 siswa SD Negeri 3 Kebulusan Kecamatan Pejagoan, Kabupaten Kebumen, Provinsi Jawa Tengah. Instrumen yang digunakan untuk mengumpulkan data adalah wawancara, kuisioner penilaian karakter permainan tradisional, kuisioner observasi pengembangan permainan tradisional, kuisioner observasi keefektifan model permainan tradisional, kuisioner penilian observasi ahli media, dan kuisioner evaluasi siswa. Hasil penelitian berupa pengembangan model permainan tradisional terdiri dari 3 jenis permainan yaitu: (1) permainan goteng, (2) lari papan/segi empat, dan (3) kasti tangan. Berdasarkan penilaian para ahli materi dan guru penjasorkes dapat disimpulkan bahwa pengembangan model permainan tradisional yang disusun sangat baik dan efektif, sehingga model permainan layak digunakan untuk pembelajaran pendidikan jasmani pada siswa kelas atas. Developing Models of Traditional Games to Build Characters of Elementary School Students of Upper Grades AbstractThe study was conducted through two stages by adapting the research and development of educational models Borg & Gall as follows (1) pre-development stage, this stage include (a) review of relevant literature and research, and (b) field studies, (2) the development stage, this stage include; (a) drafting, (b) validation expert, (c) testing of small-scale models, (d) testing large-scale models, and (e) of the final product.The small-scale tryout was conducted by involving 30 students of upper grades of state elementary schools (SES) of Aditirto, Pejagoan sub-district, Kebumen regency, Central Java porovinsi. The large-scale tryout was conducted by involving 130 students of upper grades of SES 1 of Karangpoh, 26 students of SES 1 of Logede, 22 students of SES 4 of Pejagoan, 24 students of SES 1 of Kebulusan, and 30 students of SES 3 of Kebulusan Pejagoan sub-district, Kebumen regency, Central Java porovinsi. The data collecting instruments were an interview guideline, a questionnaire to assess characters of traditional games, a questionnaire to assess the traditional game development, a questionnaire for the assessment by the media expert, and a questionnaire for the evaluation by students. The results of the study of the development of models of traditional games were three types of games, i.e: (1) goteng game, (2) board/rectangle running, and (3) hand kasti. Based on the assessment by the materials experts and the teachers of physical, sports, and health education, it could be concluded that the developed modals of traditional games were very good and effective so that they were appropriate to be used in the learning physical education for the students of upper grades.
16
Firdaus, Radin, Mohamad Shaharudin Samsurijan, Paramjit Singh Jamir Singh, Mohd Haizzan Yahaya, Abdul Rais Abdul Latiff, and Kumarashwaran Vadevelu. "Impak perubahan iklim ke atas pertanian berdasarkan Model Simulasi Pertumbuhan Tanaman (CGS)." Malaysian Journal of Society and Space 14, no. 3 (August 27, 2018): 53–66. http://dx.doi.org/10.17576/geo-2018-1403-05.
Full text
17
Fazel, Farhad, Abdollah Golmohammadi, Gholamhossein Shahgholi, and Ebrahim Ahmadi. "Predictions of the Apple Bruise Volume on the Basis of Impact Energy or Maximum Contact Force Using Adaptive Neuro-Fuzzy Inference System (ANFIS)." Acta Technologica Agriculturae 23, no. 3 (September 1, 2020): 118–25. http://dx.doi.org/10.2478/ata-2020-0019.
Full textAbstract:
AbstractFruit quality drops significantly due to physical impacts and contact forces. Stress on the fruit surface during harvesting, transportation and storage operations causes bruising in its tissue and eventually result in fruit failure. Therefore, prediction of the bruise volume caused by impacts can be very important. In this research, adaptive neuro fuzzy inference system (ANFIS) was used to predict the bruise volume caused by the impacts on apples. The input parameters were the maximum contact force or impact energy; curvature radius at the contact point; temperature; and fruit mass. Its response was the bruise volume. The results show that the ANFIS models operated better in the bruise volume prediction than regression models. Between different available ANFIS models, the model based on the grid partitioning showed the best results with a mean squared error of MSE = 0.00015941, which was less than value showed by the sub-clustering mode. However, its implementation time to reach a fixed error was longer. Eventually, impact energy-based models, in contrast to maximum contact force-based models, were more capable in terms of the apple bruising prediction.
18
Dairo, Olawale Usman, Adewole Ayobami Aderinlewo, Olayemi Johnson Adeosun, Ibukun Adekola Ola, and Tolulope Salaudeen. "Solar Drying Kinetics of Cass Ava Slices in a Mixed Flow Dryer." Acta Technologica Agriculturae 18, no. 4 (December 1, 2015): 102–7. http://dx.doi.org/10.1515/ata-2015-0020.
Full textAbstract:
Abstract Drying characteristics of cassava slices was investigated in a mixed mode natural convection solar dryer to obtain a suitable mathematical model describing the drying. The average drying chamber temperature was between 34 ±2 °C and 50 ±1.8 °C, while 10 commonly used thin layer drying models were used for drying curve modelling. Coefficient of determination (R2) and root mean square error (RMSE) were used to determine the models performances. The drying curve of cassava slices showed a reduction of moisture content with increased drying time in the solar dryer, and the variation of moisture ratio exponentially decreased with increased drying time. The Midilli and Logarithmic models showed better fit to the experimental drying data of cassava slices. As compared with other models tested, there were no significant differences (p >0.05) in the R2 values obtained for the Midilli and Logarithmic models; hence, the Logarithmic model was preferable because of the lower RMSE. The diffusion mechanism could be used to describe the drying of cassava slices that was found to be in the falling rate period. A diffusion coefficient (Deff) of 1.22 × 10-8 m2 s-1 was obtained, which was within the established standard for food products.
19
Muhtador, Moh. "Studi Kritis atas Transmisi dan Otoritas Keagamaan di Media Sosial." FIKRAH 6, no. 2 (December 27, 2018): 323. http://dx.doi.org/10.21043/fikrah.v6i2.2765.
Full textAbstract:
The development of social media raises a problem related to social change authorities such as thinking paradigms, social behavior, and religious models. This article aims to criticize the development of religious teachings found on social media. The method used is descriptive-critical by using the authority theory Abou El Fadl to assess and analyze the development of religious models in social media while transmission theory to find the authenticity of religious teachings. The result is known that the development of religious models on social media does not display scientific transmission. Religious developments that exist in social media tend to be textual-dogmatic in style, thus impacting on a stagnant religious attitude. The importance of this article is to provide a critical review of the development of religious knowledge found on social media. The critical study lies in the aspect of substance (material) or aspects of transmission (narrator). The authenticity and the development of religious teachings on social media can be known.
20
Asmiah, Asmiah. "UPAYA PENINGKATAN HASIL BELAJAR MATEMATIKA SISWA MELALUI MODEL PEMBELAJARAN KOOPERATIF TIPETUTOR SEBAYA DI SMP NEGERI 3 SATU ATAP BANGUN PURBA." SCHOOL EDUCATION JOURNAL PGSD FIP UNIMED 4, no. 1 (December 15, 2015): 116–26. http://dx.doi.org/10.24114/sejpgsd.v4i1.2981.
Full text
21
Ramlie, Habibah Artini, and Norshahrul Marzuki Mohd. Nor. "DEVELOPMENT OF AN ONLINE EDUCATION COMMUNITY SERVICE (OECS) MODEL BASED ON SULAM (SERVICE LEARNING MALAYSIA – UNIVERSITY FOR SOCIETY)." Journal of Tourism, Hospitality and Environment Management 6, no. 25 (October 31, 2021): 77–91. http://dx.doi.org/10.35631/jthem.625007.
Full textAbstract:
This paper proposes the development of an Online Education Community Service (OECS) Model based on SULAM (Service Learning Malaysia - University For Society). It aims to fulfil the needs for student community service activities that could not be conducted in-person or face-to-face due to movement restrictions during the COVID-19 pandemic. The suggestions in this paper are based on qualitative findings through literature reviews pertaining to community service among students. Several research methodologies and sampling techniques are proposed for the development of the model. One of these suggestions is adopting the Design and Development Research approach that could be developed in phases namely the needs analysis phase, the model component design phase, and the model development phase. The needs analysis phase involves reviewing literature using the content analysis technique. The model component design phase includes semi-structured interviews with students, lecturers, and community members whereas the questionnaire survey will be conducted among students only. Interview data is to be analysed using NVivo while questionnaire data from the pilot study and actual study will be analysed using SPSS. The model development phase involves conducting expert consensus workshops using the Fuzzy Delphi Method based on verified findings from the first and second phases of the study. Findings from the model development phase are to be analysed using Excels software. This proposed development of the SULAM-based OECS is in line with the Ministry of Higher Education’s aspiration to combine course learning outcomes with the aspect of community service to produce holistic students. Hence, students will be able to share their knowledge and skills obtained in university with the community in the effort to turn institutions of higher learning into Centres of Excellence. It is also in line with the country’s vision of achieving mutual prosperity by 2030 and the Sustainable Development Goals, specifically the goal of Quality Education.
22
Jackson, Mark, Sonja Pippin, and Jeffrey A. Wong. "Asset and Business Valuation in Estate Tax Cases: The Role of the Courts." Journal of the American Taxation Association 35, no. 2 (March 1, 2013): 121–34. http://dx.doi.org/10.2308/atax-50460.
Full textAbstract:
ABSTRACT The U.S. court system plays an important role in resolving asset valuation disagreements between taxpayers and the taxing authority. Prior literature suggests that in estate tax cases, courts act as compromisers choosing a value somewhere between the estimates arrived at by the taxpayer and the Internal Revenue Service (IRS). Some studies argue that the tax courts choose the arithmetic mean between the two estimates. Using models from prior literature and an updated dataset, we reexamine the role of the courts in appraising disputed asset value estimates and find that the courts do not simply use the mean value between taxpayer and IRS asset valuation estimates. In addition to testing the concept of courts acting as compromisers, we investigate whether there are certain factors related to the case and the judge that may be correlated with the judge's decision. We find evidence that suggests that the number of appraisers used by the taxpayer, the political affiliation of the judge, the type of asset being valued, and the age and complexity of the case are related to the decisions of the court. Our study should be of interest to taxpayers, the IRS, the courts, and tax researchers.
23
Sunmonu, Musliu Olushola, Michael Mayokun Odewole, Ibukunolowa Omotola Oyeleke, Grace Olufunke Otitodun, Mobolaji Omobowale, and Moses Odunayo Ogundare. "Empirical Models and Process Optimization for Prediction of Nutritional Parameters of Stored Cowpea Variety (IT96D-610K)." Acta Technologica Agriculturae 21, no. 4 (December 1, 2018): 141–48. http://dx.doi.org/10.2478/ata-2018-0026.
Full textAbstract:
Abstract This paper presents a study carried out to develop empirical models and process optimization for prediction of nutritional parameters of stored cowpea variety (IT96D-610K). Twelve small scale prototype silos made of two different materials (wooden and galvanised mild steel) were constructed and used in the storage of the cowpea for a 4-month period. Seven kilograms of cowpea at 9.88% moisture content admixed with DE having two different particle sizes (7.5 × 10−5 m and 9 × 10−5 m) and three different concentrations (0.0001 kg, 0.00005 kg and 0 kg) in varying combinations were loaded into each prototype silo structure. The control (zero/no concentration) was set without the use of DE in each of the wooden and galvanised mild steel structures, respectively. Temperature, relative humidity and moisture content within the storage structures were monitored. Nutritional parameters such as ash, crude protein, fat, crude fibre, and carbohydrate content were also measured alongside moisture. Significant differences (P <0.05) were observed between the control sample and treated samples. Six model equations using Essential Regression Software package were further generated to determine the relationship between input and output parameters, and were checked for adequacy and validity. The model equations developed were used to get the optimum values of output parameters which are: minimum moisture content (8.87%), minimum ash content (4.07%), maximum crude protein (22.86%), maximum fat (2.04%), maximum crude fibre (2.26%) and maximum carbohydrate (60.31%) of the stored cowpea at various conditions. Study results show that all the storage conditions had significant effects at P <0.05.
24
Badouna, Baha-Eddine, and El-Hadi Mechentel. "Contribution for Establishment of Software for Determining the Tensile Strength of Agricultural Tools. Simple and Complex Shaped Tools." Acta Technologica Agriculturae 25, no. 4 (November 1, 2022): 211–20. http://dx.doi.org/10.2478/ata-2022-0031.
Full textAbstract:
Abstract The importance of evaluating the energy requirements of soil preparation operations is a concern of researchers specializing in agricultural equipment. To answer such a question, they have proposed several mathematical models for the evaluation of tensile strength. However, given the large number of parameters introduced in these models, the selection of one of these models under specific agro-pedological conditions often poses an issue. Knowing the difficulties of selecting a mathematical model from those proposed in literature, the work presented allows a judicious choice of the model to be used, taking into account the precise working conditions. The work employs the MERISE method (it is a method of analysis, design and management of IT projects) to realize this work. For these purposes, a computer program was designed to quickly determine the tractive effort from a system of information on predefined equipment and working conditions. This program is called DERT (Fr: Détermination de l‘Effort de Résistance à la Traction; En: Determination of Traction Resistance Effort) and grants the possibility to convert the traction effort into energy using the most appropriate mathematical model. This computer tool enables the establishment of a database on the tractive effort and energy requirements of mechanized agricultural work. Eighteen farms permitted testing the DERT program to evaluate the efforts using the appropriate models. A generalization of its use at the level of different farms will allow the creation of a national map of energy needs and thus the optimization of agricultural equipment and energy consumption.
25
Plummer, Elizabeth. "The Effects of Protest Format and Agent Use on Residential Appeals Adjustments." Journal of the American Taxation Association 37, no. 1 (December 1, 2014): 205–36. http://dx.doi.org/10.2308/atax-50990.
Full textAbstract:
ABSTRACT This study examines how protest format and use of an agent affect the magnitude of the adjustments obtained in property tax appeals. The sample includes all single-family residential properties in Harris County, Texas for which a property tax protest was filed in 2010 or 2011 (n = 290,022). A protest can be settled in one of three formats: electronically (only when an agent is not used), an informal hearing, or a formal hearing. Because an owner's decision to use an agent is voluntary, I use a two-stage estimation process to help control for potential selection bias. The first-stage probit model is used to generate the predicted probability that an owner will use an agent, while the second-stage Tobit regression models the appeals adjustment as a function of protest format, agent use, control variables, and the selection-bias variable. Empirical results show that when an owner does not use an agent, appeals adjustments for electronic settlements are smaller than for informal settlements, and appeals adjustments for informal settlements are smaller than for formal settlements. When an agent is used, results show the opposite: appeals adjustments for informal settlements are greater than for formal settlements. Results also show that appeals adjustments are smaller when an agent is used compared with owners representing themselves, regardless of whether the hearing is formal or informal. Results are generally consistent with agency problems whereby property tax agents accept suboptimal appeals adjustments. Results from the first-stage probit model provide evidence on factors that affect the likelihood that an owner will use an agent.
26
Kuleshkov, Yuri V., Timofey V. Rudenko, Mikhailo V. Krasota, Miroslav Bošanský, and František Tóth. "Performance Features of Tooth Gearing in Gear Hydraulic Machines." Acta Technologica Agriculturae 24, no. 2 (May 21, 2021): 84–91. http://dx.doi.org/10.2478/ata-2021-0014.
Full textAbstract:
Abstract The paper presented determines that the rotation velocities of gears and radii connecting the axes of rotation of the gears with the point of their teeth gearing are not equal with each other. It is explained by the relative slip of involute gear profiles during their rolling. This phenomenon will become a prerequisite for further development of creation of mathematical models in the context of theory of gear hydraulic machines. The models can explain a number of specific phenomena in the operation of gear hydraulic machines, such as pressure and input pulsations, dynamics of hydraulic oil in the cut-off plane, combined torque pulsations in gear hydraulic motors and others.
27
Cviklovič, Vladimír, Rastislav Srnánek, Dušan Hrubý, and Marta Harničárová. "The Control Reversing Algorithm for Autonomous Vehicles with PSD-Controlled Trailers." Acta Technologica Agriculturae 24, no. 4 (December 1, 2021): 187–94. http://dx.doi.org/10.2478/ata-2021-0031.
Full textAbstract:
Abstract Driving a vehicle with a passive trailer has been the subject of numerous studies. Current control strategies are mostly used by differential geometry, linear algebra, fuzzy regulators, and artificial neural networks. The objective of this study is to design an algorithm for autonomous control of the tractor-trailer system reversing based on an algorithm using a PSD controller and to verify it on a simulated mathematical model. All parameters listed in the models and experiments are performed based on the existing tractor-trailer system. Dynamic models of steering and velocity control were identified and incorporated into the simulation. Result includes a stable operation of the steering without oscillating. The proposed algorithm can be implemented in microcontrollers without the need for high computing power.
28
Rully, Tutus, and Ardiansyah Nurrohman. "PERANAN PENGENDALIAN MUTU DENGAN MENGGUNAKAN METODE SQC DAN DIAGRAM SEBAB AKIBAT GUNA MENGURANGU PRODUK CACAT PADA OZI AIRCRAFT MODELS." JIMFE (Jurnal Ilmiah Manajemen Fakultas Ekonomi) 5, no. 2 (December 31, 2013): 62–69. http://dx.doi.org/10.34203/jimfe.v5i2.708.
Full textAbstract:
ABSTRAKOzi Aircraft Models adalah perusahaan yang bergerak dibidang manufaktur, denganberkembangannya teknologi dan informasi dijamanin membuat perusaahaan sulitmempertahankan stabilitas perusahaannya dengan persaingan perusahaan yang sejenis.Tujuan penelitian ini dilakukan adalah untuk mengatasi masalah produk cacat, makadibutuhkannya pengendalian mutu terhadap proses produksi untuk mengetahui seberapabesar produk cacat yang dihasilkan kemudian untuk melihat dimana letak kesalahan disaatproses pruksi saat berlangsung.Berdasarkan uraian di atas penulis melakukan penelitian pada Ozi Aircraft Models, makadidapatlah tingkat-tingkat kerusakan produk sebesar 1.63% CL, 3,37% UCL dan -0,10%LCL. Seta jumlah produk cacat berdasarkan jenisnya keropos 27, 12%, permukaan masihkasar 16,95%, lecet 22,88%, warna pudar 16,10% dan patah 16,95%. Hal ini disebabkan olehpemilihan bahan baku yang kurang selektif hingga produk yang dihasilkan kurang baik, umurmein yang sudah tua sehingga banyak komponen mesin yang haus dan tenaga ahli yangkurang terampil atau kurang konsentrasi dalam pengerjaannya.Berdasarkan analisa penulis dengan melihat data yang ada penulis dapat menyimpulkanbahwa proses produksi yang dilakukan oleh Ozi Aircraft Models belum baik.Kata kunci : produksi dan operasi, mutu, pengendalian mutu, dan produk cacat.
29
Hardy, Jack A., Ute R�mer, and Audrey Roberson. "The Power of Relevant Models: Using a Corpus of Student Writing to Introduce Discipinary Practices in a First Year Compsition Course." Across the Disciplines 12, no. 1 (2015): 1–20. http://dx.doi.org/10.37514/atd-j.2015.12.1.01.
Full text
30
Abbaspour-Gilandeh, Yousef, and Mohammadreza Abbaspour-Gilandeh. "Application of Computational Intelligence Methods for Predicting Soil Strength." Acta Technologica Agriculturae 22, no. 3 (September 1, 2019): 80–85. http://dx.doi.org/10.2478/ata-2019-0015.
Full textAbstract:
Abstract The aim of this study was to make predictions for soil cone index using artificial neural networks (ANNs), adaptive neuro-fuzzy inference system (ANFIS) and a regression model. Field tests were conducted on three soil textures and obtained results were analyzed by application of a factorial experiment based on a Randomized Complete Block Design with five replications. The four independent variables of percentage of soil moisture content, soil bulk density, electrical conductivity and sampling depth were used to predict soil cone index by ANNs, ANFIS and a regression model. The ANNs design was that of back propagation multilayer networks. Predictions of soil cone index with ANFIS were made using the hybrid learning model. Comparison of results acquired from ANNs, ANFIS and regression models showed that the ANFIS model could predict soil cone index values more accurately than ANNs and regression models. Considering the ANFIS model, a novel result on soil compaction modeling, relative error (ε), and regression coefficient (R2) were calculated at 2.54% and 0.979, respectively.
31
Gunawarman, Anak Agung Gede Raka. "KONSEP DESAIN MITIGASI BENCANA KEBAKARAN PADA BANGUNAN PURA BERATAP IJUK." Jurnal Arsitektur ZONASI 2, no. 1 (February 11, 2019): 25. http://dx.doi.org/10.17509/jaz.v2i1.15058.
Full textAbstract:
Abstract: The use of Palm-Fiber roof on sacred buildings in Balinese Temples still preserved well, however case of fire disasters becoming a threat in temple existence nowadays. Fire disasters could start with some sparks on roof section. Palm fiber and thatched roof are building materials that very vulnerable to fire disasters and when fire disaster happens because of this materials,it could easily spread out the fire on other building next to it. This article was an article created by purposed to give an idea or innovation in fire disasters mitigation especially in temples or “palinggih” with palm-fiber roof. Content explanation using concept design model and system scenarios related to extinguished fire with conventional fire extinguisher tool. Automatic fire extinguisher concept design which installed on roof section of building or “palinggih” with palm fiber roof only had two alternative models. First model for building with roof sized not more than 3x3m, and second model for roof sized more than 3x3m. The Consideration is head sprinkler that only could served on 3 m maximum radius. This article still a concept design and still need some testing on the field on next research. Keywords: mitigations, fire disasters, palm-fiber roof Abstrak: Penggunaan atap ijuk pada bangunan-bangunan suci di pura-pura di Bali masih tetap terjaga dengan baik. Namun, beberapa permasalahan yang terjadi belakangan ini adalah banyaknya kebakaran yang terjadi di pura-pura dan diawali dari percikan api pada bagian atap. Atap ijuk dan atap alang-alang adalah material yang sangat mudah terbakar dan mudah menjalar ke bangunan lain. Hal itu juga terjadi disaat terjadi kebakaran di atap ijuk bangunan pura yang memiliki lebih dari satu bangunan beratap ijuk dengan posisi yang berdekatan. Tulisan ini merupakan sebuah tulisan yang bertujuan untuk memberikan gagasan dan inovasi dalam mitigasi bencana kebakaran khususya di pura atau palinggih dengan atap ijuk. Penjelasan materi dengan menggunakan model desain konsep dan skenario sistem-sistem pemadam kebakaran dengan perlengkapan yang digunakan pada sistem pemadam pada umumnya. Konsep desain pemadam kebakaran otomatis yang dipasang pada bagian atap dari bangunan atau palinggih dengan atap ijuk untuk saat ini hanya mempunyai dua alternatif model. Model pertama diperuntukkan untuk bangunan dengan atap berukuran tidak lebih dari 3x3m, dan model kedua untuk atap yang berukuran lebih dari 3x3 m. Pertimbangannya adalah head sprinkler yang hanya mampu melayani radius maksimum 3 m.Tulisan ini masih berupa desain konsep dan masih perlu uji coba di tahap berikutnya.Kata Kunci: mitigasi, kebakaran, atap ijuk
32
Sa’dan, Masthuriyah. "POLIGAMI ATAS NAMA AGAMA: Studi Kasus Kiai Madura." ESENSIA: Jurnal Ilmu-Ilmu Ushuluddin 16, no. 1 (April 1, 2015): 89. http://dx.doi.org/10.14421/esensia.v16i1.989.
Full textAbstract:
Having more than one wife for Madurese Kyai is not unusual. In fact, parents would feel proud and happy when their daughters are proposed to be one of the Kyai’s wifes. This discussion exclude the fact of socio economic factors and the low level of knowledge and education among Madurese girls. In this context, some Kyais that served as role models and religious leaders, have taken the benefit through the theological proposition that polygamy is the sunnah of the Prophet and Islam. It is urgent then to reconstruct the paradigms of some kyais and Madurese community. Applying a contemporary socio humanities approach and Feminist Islamic analysis, the article constitutes that polygamy is the result of unfair religious interpretations of gender. In this regard, polygamy is a crime in the form of marriage since polygamy is only for the man’s libido and sexual modus. In other word, polygamy violates women and children’s human rights.
33
Afwadzi, Benny. "TINJAUAN SEMIOTIKA ATAS PEMAHAMAN HADITH DALAM KITAB FATH ALBARI KARYA IBN HAJAR AL‘ASQALANI." Al-A'raf : Jurnal Pemikiran Islam dan Filsafat 17, no. 1 (June 30, 2020): 97–138. http://dx.doi.org/10.22515/ajpif.v17i1.1935.
Full textAbstract:
This article aims to analyze semiotically on the Muslim scholars' understanding of the hadith in Fath Albari, written by Ibn Hajar Al‘asqalani. Focus of the study refers to three things; understanding models, examining semiotically (significance and communication) on understanding models, and contribution of semiotics in the hadith understanding discourse. By making two hadiths as its analysis objects; first, the hadith about believers who eat with one intestine and infidels with seven intestines; second, the hadith regarding the deeds most loved by Allah SWT. The results of the study show that the understanding model of hadith in Fath Albari is divided into textual (symbolic and non-symbolic) and contextual (symbolic and non-symbolic) models of understanding. This model, semiotically (significance and communication) has given a new nuance in the study of hadith understanding. The understanding model of the first hadith, in semiotic significance, indicates the existence of an understanding model with a signifier of denotation and connotation levels. In semiotic communication, the understanding model of the second hadith is seen more systematic because it elaborates reasoning continuously, and shows the important contribution of semiotics in the hadith understanding discourse, like eliminating truth claims and being media of developing textual and contextual understanding.
34
Zulaika, Dhiyaa, and Novita. "Karakteristik, Profesionalisme, Skeptisisme Profesional terhadap Persepsi Auditor atas Red Flags." JRB-Jurnal Riset Bisnis 4, no. 2 (April 29, 2021): 122–40. http://dx.doi.org/10.35814/jrb.v4i2.1887.
Full textAbstract:
Purpose of this study was to determine effect of characteristics, professionalism, and professional skepticism on auditor’s perceptions of red flags. The data in this study were obtained through distributing questionnaires, which were filled out by 100 auditors who consistently participated in Continuing Professional Training organized by Indonesian Institute of Public Accountants. This study uses quantitative approach, data analysis using SmartPLS software to measure outer and inner models. The results of this study indicate characteristics had no effect on auditor’s perceptions of red flags, professionalism had effect on auditor’s perceptions of red flags, and professional skepticism had effect on auditor’s perceptions of red flags.
35
Stašák, Jozef. "How image and text semantic analysis systems can be applied for educational and teaching purposes." Acta Technologica Dubnicae 1, no. 1 (July 1, 2011): 1–18. http://dx.doi.org/10.1515/atd-2015-0036.
Full textAbstract:
AbstractThis contribution deals with algorithm closely related to design and implementation of simple database conceptual models based on terms and principles concerned to image and text semantic analysis, while the term deterministic image is being postulated and introduced and its structure elements are described. On the other hand, the presented contribution contains a set of adequate information, how that algorithm may be applied in teaching concerned to simple database conceptual model.
36
Syarif, Nurrohman. "Syariat Islam dalam Perspektif Negara Hukum Berdasar Pancasila." Pandecta: Research Law Journal 11, no. 2 (May 31, 2017): 160–73. http://dx.doi.org/10.15294/pandecta.v11i2.7829.
Full textAbstract:
Revitalisasi ideologi dalam perspektif Islam, baik pada tingkat nasional maupun global selalu bermuara pada aspirasi dan tuntutan untuk mengimplementasikan syariat atau hukum Islam secara total (kaffah). Dalam Negara hukum Indonesia, aspirasi dan tuntutan semacam itu tidak selalu bisa dipenuhi. Hal ini karena Negara hukum Indonesia, sejak awal dibangun atas dasar semangat kebangsaan yang didasarkan atas prinsip ketuhanan, kemanusiaan, keadilan, dan kesetaraan atau persamaan bagi setiap warga Negara didepan hukum. Oleh karena itu aspirasi dan tuntutan penerapan syariat Islam selalu mengalami kendala bila didalamnya terdapat unsur diskriminatif atau unsur lain yang dapat menghilangkan jaminan dan perlindungan terhadap hak asasi warga negara yang sudah dijamin oleh konstitusi. Paper ini akan menjelaskan tentang pengertian dan karakter syariat, tujuan syariat, model-model penerapan syariat di sejumlah Negara Muslim, model atau teori penerapan syariat Islam di Indonesia menurut sejumlah pakar, pilihahan atau alternative yang bisa digunakan untuk memperjuangkan aspirasi dan tuntutan implementasi syariat Islam di Indonesia dan ditutup dengan simpulan. Revitalization of ideology in Islamic perspective, both at national and global level always leads to aspirations and demands to implement sharia or Islamic law in total (kaffah). Within the legal State of Indonesia, such aspirations and demands can not always be met. This is because the Indonesian state of law, from the beginning built on the spirit of nationality based on the principle of divinity, humanity, justice, and equality or equality for every citizen in front of the law. Therefore, the aspirations and demands of the application of Islamic Sharia always experience constraints if in it there are discriminative elements or other elements that can eliminate the guarantee and protection of citizens rights that have been guaranteed by the constitution. This paper will explain the understanding and character of the Sharia, the purpose of Sharia, models of Sharia application in some Muslim countries, the model or theory of application of Islamic Shariah in Indonesia according to some experts, alternatives or alternatives that can be used to fight for aspirations and demands of the implementation of Islamic Shariah Indonesia and concluded.
37
Setyawan, Kurnia Azis, and Ria Lumintuarso. "MODEL PENGENALAN PERMAINAN DALAM PEMBELAJARAN LOMPAT JAUH PADA SISWA KELAS ATAS SEKOLAH DASAR." Jurnal Keolahragaan 3, no. 2 (October 28, 2015): 208–17. http://dx.doi.org/10.21831/jk.v3i2.6245.
Full textAbstract:
Penelitian ini bertujuan untuk menghasilkan model pengenalan pembelajaran lompat jauh pada siswa sekolah dasar (SD) kelas atas tahun pelajaran 2013/2014 di Kecamatan Srumbung, Kabupaten Magelang. Model pembelajaran yang dikembangkan diharapkan untuk digunakan guru SD sebagai salah satu bentuk pembelajaran lompat jauh yang baik dan efektif. Penelitian pengembangan ini dilakukan dengan mengadaptasi langkah-langkah penelitian pengembangan sebagai berikut: (1) pengumpulan informasi di lapangan, (2) melakukan analisis terhadap informasi yang telah dikumpul-kan, (3) mengembangkan produk awal (draf model), (4) validasi ahli dan revisi, (5) uji coba lapangan skala kecil dan revisi, (6) uji coba lapangan skala besar dan revisi, dan (7) pembuatan produk final. Uji coba skala kecil dilakukan terhadap siswa kelas 5 SD N Tegalrandu dan SD N Polengan, Kecamatan Srumbung yang berjumlah 31 siswa. Uji coba skala besar dilakukan terhadap siswa kelas 5 SD N Tegalrandu, SD N Polengan, SD N Pucanganom, SD N Pandanretno, SD N Soka 1 yang berjumlah 81 siswa. Instrumen pengumpulan data yang digunakan yaitu; (1) pedoman wawancara, (2) skala nilai, (3) pedoman observasi model pembelajaran, (4) pedoman observasi keefektifan model pembelajaran. Teknik analisis data yang dilakukan yaitu analisis deskriptif kuantitatif dan analisis deskriptif kualitatif. Hasil penelitian ini berupa buku dan video model pengenalan dalam pembelajaran lompat jauh pada SD kelas atas. Berdasarkan penilaian ahli materi cabang olahraga atletik dan guru penjasor-kes, produk model pengenalan dalam pembelajaran lompat jauh pada SD kelas atas, sudah sesuai dan layak untuk digunakan oleh guru penjasorkes dalam mengajarkan materi lompat jauh kepada siswanya dengan nilai rata-rata 98,1%. Kata kunci: pengembangan, permainan, model pengenalan pembelajaran lompat jauh INTRODUCTION MODELS IN LEARNING GAMES OF LONG JUMP IN UPPER CLASS ELEMENTARY SCHOOL Abstract This study aims to produce introduction models of the learning long jump at the upper class of elementary school students in the Academic Year 2013/2014 in Srumbung District, Magelang regency. The developed models are expected to be used by elementary school teachers to teach long jump well and effectively. The study was conducted by adapting the development steps of research development as follows: (1) collecting information in the field, (2) analyzing information that has been collected, (3) developing initial products (draft model), (4) validating by experts and revising, (5) small-scale field trials and revisions, (6) large-scale field trials and revisions, and (7) making the final product. Small-scale trials were carried out to the 5th grade students at SD N Tegalrandu and SD N Polengan, District Srumbung totaling 31 students. Large-scale trials were carried out to the 5th grade students of Tegalrandu, SD N Polengan, SD N Pucanganom, SD N Pandanretno, SD N Soka 1, amounting to 81 students. Data collection instruments used were; (1) interview guide line, (2) the scale of values, (3) learning models observation guide line, (4) observation guide line of the effectivenes learning models. The data were analyzed using quantitative and qualitative descriptive analysis. The final products of the research are in the form of books and videos of introduction models of the learning long jump at the upper class of elementary schools. The developed products were considered suitable and appropriate to be used by SD N teaches based on to judgement by material experts of athletics and penjasorkes teachers with the mean scale 98,1%. Keywords: development, game, introduction model of learning long jump
38
Fardmanesh, Majid, Razieh Pourdarbani, and Bahman Najafi. "Methane Production Potential of Azolla Under Different Ratios of C/N, Chemical and Thermal Pre-Treatment." Acta Technologica Agriculturae 23, no. 3 (September 1, 2020): 126–31. http://dx.doi.org/10.2478/ata-2020-0020.
Full textAbstract:
AbstractAzolla algae currently represent a major threat to the environment and rice cultivation fields. Various studies have shown that one of the practical solutions is to turn this threat into an opportunity for biomass energy production. This research investigates the production potential of methane in Azolla. Test was conducted in a completely randomized design (CRD) with Mini Tap software. Three different C/N ratios, 30, 34 and 38, two levels of thermal pre-treatment (raw and steamed Azolla) and two levels of chemical pre-treatment (NaOH 0% and 9%) were used and effects of each case on the methane production rate was studied. The highest amount of methane (247.7 ml·g−1vs) was produced at C/N ratio of 30 with application of NaOH (9%) and no thermal pre-treatment (raw Azolla). ANOVA analysis showed that interactions of the effective variables were significant, but the trend was not incremental or decreasing; therefore, ANFIS and stepwise regression modelling were used. The results showed that the ANFIS model provides more accurate mapping between the empirical and predicted values than the regression model. Furthermore, among examined models (triangular; trapezoidal; Gaussian; bell-shaped models), the best model for methane production prediction was Gaussian linear membership function (R2 = 0.997 and ε (%) = 0.32). According to the regression model, the thermal-chemical factor is the most efficient in prediction of the model (b = 35.6).
39
Nagy, Ádám, and Levente Székely. "The Basis and the Structure of the Tertiary Socialization Field and the “Youth-Affairs” as an Autonomous Area." Acta Technologica Dubnicae 2, no. 2 (December 1, 2012): 1–18. http://dx.doi.org/10.1515/atd-2015-0055.
Full textAbstract:
AbstractMany models have been made during the study of the chronology and areas of the socialization process and thus the extrafamilial and extracurricular platforms have often been in focus. Many theories have been created about the periods preceding adulthood, i.e. youth. Now, on the borderline of the two areas a new profession is in the making, targeting youth in an extrafamilial and extracurricular context. This new area deserves thorough analysis with a focus on theoretical background since models of leisure environments outside the family and school are now on the same footing with youth education and socialization. The current study deals with leisure environment and youth. It reviews theories of socialization environments and venues, provides a grouping of them and introduces a new theory that best fits into the conceptual apparatus of the youth area and serves as a solid foundation for it. In addition, scientific and international agreements pertaining to the periods of youth will be looked at, and an attempt will be made to create a break-down by age group that is best adaptable to the extrafamilial and curricular environment. It must be stressed that the present study does not deal with the repertory of socialization themes, such as gender socialization, moral socialization, political socialization and others, but merely those environments where these take place.
40
Winter-Holt, Jon J., Catherine Bardelle, Elisabetta Chiarparin, Ian L. Dale, Paul R. J. Davey, Nichola L. Davies, Christopher Denz, et al. "Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models." Journal of Medicinal Chemistry 65, no. 4 (February 8, 2022): 3306–31. http://dx.doi.org/10.1021/acs.jmedchem.1c01871.
Full text
41
Achmad, Nur, and Edy Purwo Saputro. "Model Keperilakuan Atas Konsumsi Produk Bajakan." Jurnal Ekonomi dan Bisnis 18, no. 1 (August 1, 2016): 1. http://dx.doi.org/10.24914/jeb.v19i1.478.
Full textAbstract:
<p><em>Behavioral research on the case of mp3 music downloading is an interesting study since this case seems correlated to many occasions. An empiric study results that this kind of behavior happens not merely in the developed industrial countries but also in developing countries. On the one side, the results from empirical research indicates various factors, and on the other side there is research gap suitable for the observation settings in this research. This research aims to find out the behavioral models on the consumption of piracy products, especially concerning on the mp3 music downloading. This research involves a number of 100 students for the research samples, and utilizes structural analysis supported by maximum likelihood method. Indirectly, the result is reinforcing the arguments related to the various factors which is enforcing mp3 music downloading behaviors, although from the other point of view, this research found the importance of rational model on the mp3 music downloading behavior. The limitedness on this research will become a suggestion for the future research to the variable explorations and observation settings in order to support the generalization process of the results in accordance with behavioral research.</em></p><p> </p><p>Abstrak<br /> <br />Penelitian keperilakuan berkenaan dengan kasus pengunduhan file musik dalam format mp3 merupakan sebuah studi yang menarik oleh karena hal ini tampaknya berkorelasi dengan berbagai kegiatan. Hasil-hasil studi empirik menunjukkan bahwa perilaku semacam itu terjadi bukan hanya di negara-negara maju tetapi juga di negara-negara sedang berkembang. Di satu sisi, hasil-hasil penelitian empiris menunjukkan terdapat berbagai faktor, namun di sisi lain masih terdapat kesenjangan penelitian yang dapat diobservasi. Penelitian ini bertujuan untuk mengetahui perilaku pada konsumsi produk bajakan, terutama menyangkut pada pengunduhan file musik dalam format mp3. Penelitian ini melibatkan 100 siswa sebagai sampel penelitian dan menggunakan analisis struktural yang didukung dengan metode maximum likelihood. Secara tidak langsung, hasil penelitian ini memperkuat argumen terkait dengan berbagai faktor yang mendorong perilaku untuk mengunduh file musik dalam format mp3, meskipun dari sudut pandang lain, penelitian ini menemukan pentingnya model rasional pada perilaku mengunduh file musik dalam format mp3. Keterbatasan pada penelitian ini menjadi saran untuk penelitian masa depan, yakni berkaitan dengan eksplorasi variabel dan pengaturan observasi dalam rangka mendukung proses generalisasi penelitian keperilakuan.</p>
42
Zakaria, Nor Asimah. "PENILAIAN PELAKSANAAN KURIKULUM MATA PELAJARAN SAINS RUMAH TANGGA MENGGUNAKAN MODEL STAKE COUNTENANCE: SATU KAJIAN LITERATUR." Journal of Vocational Education Studies 2, no. 1 (August 14, 2019): 37. http://dx.doi.org/10.12928/joves.v2i1.647.
Full textAbstract:
The purpose of this concept paper was to discuss and analysis evaluation models using in the curriculum implementation or educational program evaluation. This paper focused on secondry school home science education subject and Stake Countenance Model. This model focused on congruence between what was intended to occur and what was actually observed to occur before, during, and after curriculum implementation. The Stake Countenance Model used antecedents, transactions and outcomes as a core concepts to structure the view of the curriculum implementation evaluation or an educational program evaluation. The Stake model demonstrated its effectiveness by facilitating a thorough examination of both quantitative and qualitative research method.Kertas konsep ini adalah bertujuan untuk membincangkan dan menganalisis model penilaian yang digunakan dalam penilaian pelaksanaan kurikulum atau program pendidikan. Kertas konsep ini memberi tumpuan kepada Mata Pelajaran Sains Rumah Tangga sekolah menengah yang diajar pada peringkat menengah atas dan Model Stake Countenance. Model ini membincangkan dua matrik iaitu matrik deskripsi dan matrik pertimbangan yang memberi tumpuan kepada kepada kesesuaian antara apa yang dirancang untuk berlaku dan apa yang sebenarnya berlaku semasa perlaksanaan dengan melakukan pemerhatian sebelum, semasa, dan selepas pelaksanaan seseuatu kurikulum atau program pendidikan. Model Stake Countenance membincangkan tiga fasa pengumpulan data; masukan, proses dan hasil sebagai teras konsep dalam penilaian pelaksanaan kurikulum atau penilaian program pendidikan. Model Stake menunjukkan keberkesanannya dengan memudahkan penilai membuat pertimbangan menyeluruh dengan menggunakan kaedah penyelidikan kuantitatif atau kualitatif.
43
Suganda, Mikkey Anggara, and Suharjana Suharjana. "PENGEMBANGAN MODEL PEMBELAJARAN BOLAVOLI PADA SISWA SEKOLAH DASAR KELAS ATAS." Jurnal Keolahragaan 1, no. 2 (September 1, 2013): 156–65. http://dx.doi.org/10.21831/jk.v1i2.2571.
Full textAbstract:
Penelitian ini bertujuan untuk menghasilkan model pembelajaran bolavoli pada siswa SD kelas atas yang layak digunakan. Model pembelajaran yang dikembangkan diharapkan untuk digunakan guru SD sebagai salah satu bentuk pembelajaran bolavoli yang baik dan efektif. Penelitian pengembangan ini dilakukan dengan mengadaptasi langkah-langkah penelitian pengembangan sebagai berikut: (1) pengumpulan informasi di lapangan, (2) melakukan analisis terhadap informasi yang telah dikumpulkan, (3) mengembangkan produk awal (draf model), (4) validasi ahli dan revisi, (5) uji coba lapangan skala kecil dan revisi, (6) uji coba lapangan skala besar dan revisi, dan (7) pembuatan produk final. Uji coba skala kecil dilakukan terhadap siswa kelas 4 dari SD Ngringin Depok Sleman yang berjumlah 36 siswa. Uji coba skala besar dilakukan terhadap siswa kelas 4 dan 5 dari SD Sarikarya Yogyakarta yang berjumlah 56 anak. Instrumen pengumpulan data yang digunakan yaitu; (1) pedoman wawancara, (2) skala nilai, (3) pedoman observasi model pembelajaran, (4) pedoman observasi keefektifan model pembelajaran. Teknik analisis data yang dilakukan yaitu analisis deskriptif kuantitatif dan analisis deskriptif kualitatif. Hasil penelitian ini yaitu berupa buku panduan model pembelajaran bolavoli pada siswa sekolah dasar kelas atas, yang berisikan empat model pembelajaran, yaitu: (1) pembelajaran teknik dasar passing bawah, (2) pembelajaran teknik dasar passing atas, (3) pembelajaran teknik dasar servis bawah dan (4) pembelajaran teknik dasar servis atas. Dari hasil penilaian para ahli materi, dapat ditarik kesimpulan bahwa model pembelajaran bolavoli yang disusun sangat baik dan efektif, sehingga model pembelajaran layak digunakan untuk pembelajaran bolavoli pada siswa di kelas atas. DEVELOPING VOLLEYBALL LEARNING MODELS FOR STUDENTS OF UPPER CLASS OF ELEMENTARY SCHOOLSAbstract This research is aimed at producing an adequate and feasible volleyball learning model for stu-dents of upper class of elementary school. This volleyball learning model is developed to help elementary teachers conducting excellent and effective volleyball learning. The research and development (R & D) was carried out by adapting the steps of research development procedure consisting of: (1) collecting information, (2) information analysis, (3) developing initial products (draft model), (4) expert validation and revision, (5) preliminary field test and revision, (6) main field test and revision, and (7) making the final product. The preliminary field test was conducted to 36 students of the fourth grade of Ngringin Elementary School Depok Sleman. The main field test was conducted to 56 students of the fourth and the fifth grade of Sarikarya Elementary School Yogyakarta. Data collection instru-ments used were (1) questionnaire guidelines, (2) rating scale, (3) observation learning model guidelines and (4) guidelines for observation effectiveness of learning model. The data were analyzed using quantitative and qualitative descriptive analyses. The result of this research is a guide book of volleyball learning model for students of upper class of elementary schools. The book contains four learning models namely: (1) basic techniques of forearm passing learning, (2) basic techniques of overhand passing learning, (3) basic forearm serve learning and (4) basic overhand serve learning. Based on some experts’ judgments, it can be concluded that the model of volleyball learning is very well orga-nized and effective. Therefore, the learning model is appropriate to be applied in volleyball learning towards students of upper class of elementary schools. Keywords: develoving, volleyball learning models
44
Hidayat, Rahmad, Khusnul Khotimah, and Agus Saputra. "MATA KULIAH WAJIB UMUM BAHASA INDONESIA DI PERGURUAN TINGGI: SEBUAH TAWARAN MODEL PEMBELAJARAN." Jurnal Ilmiah Telaah 4, no. 1 (January 1, 2019): 31. http://dx.doi.org/10.31764/telaah.v4i1.1268.
Full textAbstract:
Abstrak: Tulisan ini berisi tawaran model pembelajaran Mata Kuliah Wajib Umum Bahasa Indonesia di perguruan tinggi. Tawaran ini muncul sebagai jawaban atas kompleksitas persoalan yang dihadapi dalam pelaksanaan pembelajaran. Model pembelajaran ini merupakan jalan tengah atau kombinasi antara model pembelajaran konvensional dan model pembelajaran terbaru berdasarkan buku MKWU Bahasa Indonesia yang dikeluarkan oleh Dirjen Belmawa Ristekdikti tahun 2016. Data yang membangun tulisan ini didapat dengan melakukan observasi terhadap kegiatan perkuliahan, wawancara dengan dosen terkait, dan catatan diskusi antarpengampu Mata Kuliah Wajib Umum Bahasa Indonesia. Pada akhirnya, tawaran model pembelajaran Mata Kuliah Umum Bahasa Indonesia dapat dirumuskan.Abstract: This paper contains a model for learning Bahasa Indonesia as a Compulsory General Subject in higher education. This offer is emerged as an answer to the complexity of the problems faced in the instructions. This learning model is a combination of conventional learning models and the latest learning models based on the book of MKWU Bahasa Indonedia issued by Dirjen Belmawa Ristekdikti in 2016. The data underlying this proposal was obtained by observing lecture activities, interviewing relevant lecturers, and taking notes during discussion among Bahasa Indonesia lecturers. After all, the offer of learning models for Bahasa Indonesia Subject can be formulated.
45
Safitri, Lis, Nurlaela Nurlaela, Ulul Huda, Kuntarto Kuntarto, and Muhammad Riza Chamadi. "Pemikiran Pendidikan Ibn Tufail: Studi Atas Kitab Hay Ibn Yaqzan." Matan : Journal of Islam and Muslim Society 1, no. 1 (October 22, 2019): 1. http://dx.doi.org/10.20884/1.matan.2019.1.1.1916.
Full textAbstract:
Abu Bakr ibn Tufail, known as great Islamic philosopher, meanwhile his education idea can be found in Hayy ibn Yaqzan, his magnum opus. He lived at the golden age of Andalusia in middle age, but his education idea appropriates as a contemporary teaching model. This paper has been written by analyzing and comparing Hayy ibn Yaqzan with contemporary teaching models. Ibn Tufail used rationality and intuition as a major source of human knowledge, both represent equal knowledge. His teaching model has the same characteristics as personal method teaching with a scientific approach. He hammered at the development of self creativity of problem-solving. Discovery method and inquiry methods used as his teaching method with neuro language program of metaphor and analyze case study as a technique of learning.
46
Tere, Maria Imakulata, and Ignasius Ledot. "Komitmen hidup membiara atau hidup religius dalam perspektif komitmen organisasi." Jurnal Konseling dan Pendidikan 9, no. 3 (December 1, 2021): 226. http://dx.doi.org/10.29210/163000.
Full textAbstract:
Commitment is a promise or attachment to a particular object or subject and is related to the personal social aspect. In the context of religious life, the commitment of a religious person or who chooses to live as nun is a pledge of vows; purity, obedience and poverty. This research aims to see life commitment deepen in the perspective of organizational commitment according to Meyer and Allen. Respondents in this study were 14 junior sisters, those who were already in the relationship but still in formal assistance by formators or counselors. Qualitative research was used as a methode in this research. Of the three models of organizational commitment, affective commitment is a commitment that is in line with the commitment of religious life. The findings show that life commitment of the sisters, in the perspective of organizational commitment, is still in the process of growth towards affective commitment. The respondents need to be accompanied in order to grow towards affective commitment or commitment to religious life
47
Firmansah, Bambang, and Ning Rahayu. "Analisis Kesiapan Otoritas Pajak dalam Pemajakan atas Ekonomi Digital." JPSI (Journal of Public Sector Innovations) 5, no. 1 (December 17, 2020): 13. http://dx.doi.org/10.26740/jpsi.v5n1.p13-22.
Full textAbstract:
The patterns, forms of human behavior and the presence of many new forms of business today such as e-commerce, payment services, application services, online advertising, cloud computing, high frequency trading, participative networked platforms are influenced by the digital revolution as formulated by the OECD. Social phenomena as an effect of the rapid development of information and communication technology (ICT) known as the digital economy will certainly also change the patterns of business individuals and organizations throughout the world. With the presence of various new business models, there are many opportunities for tax avoidance schemes that are usually dominated by multinational entities (MNE). Based on this, the OECD recommends several action plans, one of which is about the digital economy. The need to detect the digital economy by the tax authorities of world countries such as Indonesia is now very large. Related to this the Indonesian government issued a unilateral regulation namely Perpu Number 1 of 2020 which later became Law No. 2 of 2020, one of which regulates taxation of the digital economy. The Indonesian tax authority seeks to respond to the dynamics of the internal and external environment called organizational readiness. This study wants to analyze whether the Indonesian tax authority is ready to tax the digital economy.
48
Thibodeau, Asa, Shubham Khetan, Alper Eroglu, Ryan Tewhey, Michael L. Stitzel, and Duygu Ucar. "CoRE-ATAC: A deep learning model for the functional classification of regulatory elements from single cell and bulk ATAC-seq data." PLOS Computational Biology 17, no. 12 (December 13, 2021): e1009670. http://dx.doi.org/10.1371/journal.pcbi.1009670.
Full textAbstract:
Cis-Regulatory elements (cis-REs) include promoters, enhancers, and insulators that regulate gene expression programs via binding of transcription factors. ATAC-seq technology effectively identifies active cis-REs in a given cell type (including from single cells) by mapping accessible chromatin at base-pair resolution. However, these maps are not immediately useful for inferring specific functions of cis-REs. For this purpose, we developed a deep learning framework (CoRE-ATAC) with novel data encoders that integrate DNA sequence (reference or personal genotypes) with ATAC-seq cut sites and read pileups. CoRE-ATAC was trained on 4 cell types (n = 6 samples/replicates) and accurately predicted known cis-RE functions from 7 cell types (n = 40 samples) that were not used in model training (mean average precision = 0.80, mean F1 score = 0.70). CoRE-ATAC enhancer predictions from 19 human islet samples coincided with genetically modulated gain/loss of enhancer activity, which was confirmed by massively parallel reporter assays (MPRAs). Finally, CoRE-ATAC effectively inferred cis-RE function from aggregate single nucleus ATAC-seq (snATAC) data from human blood-derived immune cells that overlapped with known functional annotations in sorted immune cells, which established the efficacy of these models to study cis-RE functions of rare cells without the need for cell sorting. ATAC-seq maps from primary human cells reveal individual- and cell-specific variation in cis-RE activity. CoRE-ATAC increases the functional resolution of these maps, a critical step for studying regulatory disruptions behind diseases.
49
Prasetyanto, Tri Ari, and Wawan Sundawan Suherman. "Pengembangan model latihan kebugaran jasmani bagi siswa sekolah dasar kelas atas." Jurnal Pedagogi Olahraga dan Kesehatan 3, no. 2 (December 16, 2022): 91–102. http://dx.doi.org/10.21831/jpok.v3i2.18005.
Full textAbstract:
Penelitian bertujuan untuk menghasilkan model latihan kebugaran jasmani bagi siswa sekolah dasar (SD) kelas atas. Penelitian pengembangan dilakukan dengan langkah-langkah: (1) pengumpulan informasi di lapangan; (2) analisis informasi; (3) pengembangan produk awal; (4) validasi ahli/revisi; (5) uji coba skala kecil; (6) revisi; (7) uji coba lapangan skala besar; (8) revisi akhir; dan (9) pembuatan produk final. Uji coba skala kecil berjumlah 24 siswa. Uji coba skala besar di tiga sekolah. Instrumen: (1) pedoman wawancara; (2) kuisioner; (3) pedoman observasi; (4) kuisioner uji efektivitas; dan (5) kuesioner siswa. Teknik analisis data yaitu deskriptif kuantitatif dan kualitatif. Hasil penelitian berupa model latihan kebugaran jasmani bagi siswa SD kelas atas menggunakan metode circuit training. Hasil penilaian ahli materi dan siswa, menunjukkan bahwa model yang dikembangkan dinilai baik dan efektif, dan siswa memberikan respons yang positif, sehingga model pembelajaran yang dikembangkan layak untuk digunakan. Developing a physical training model for higher primary school-age children Abstract: The study aims to review models that produce Physical fitness training for Students of Elementary School (SD) Class differences. Development Research conducted WITH Steps: (1) the collection of information in the field; (2) the analysis of information; (3) development Products Beginning; (4) validation Expert/revision; (5) testing your scale is small; (6) Revisions; (7) Field trials of your big scale; (8) the final revision; and (9) Preparation of the final product. Small-scale trials You totalling 24 students. You big-scale trials at three schools. Instrument: (1) Guidelines Interviews; (2) questionnaires; (3) Observation Guidelines; (4) the effectiveness of the test questionnaires; and (5) student questionnaires. That engineering data analysis of quantitative and qualitative descriptive. Research Model Form of Physical fitness exercises For Elementary Students Grades differences using circuit training method. Expert Assessment Results matter and Students, Models that showed Developed rated Good And Effective, response and students give a positive thing, so Learning Model Developed feasible to review use.
50
Decker, Kristin, Marisa Schmitt, Can Araman, Franziska Ebeling, Irina Dranova, Torsten Hechler, Anikó Pálfí, Andreas Pahl, and Michael Kulke. "Abstract 1761: Treatment with antibody-targeted amanitin conjugates induces tolerability in preclinical models without triggering tolerance." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1761. http://dx.doi.org/10.1158/1538-7445.am2022-1761.
Full textAbstract:
Abstract Background: Amatoxin-based antibody-drug conjugates (ATACs) are a new class of ADCs using amanitin, a specific inhibitor of RNA polymerase II, as toxic payload. A first ATAC targeting B-cell maturation antigen (BCMA) is currently being tested in phase I/II clinical trials in multiple myeloma patients. During the clinical trials, the effect of repeated dosing on safety as well as anti-tumor efficacy of the ATAC will be assessed. In preclinical studies a reduction of toxicity was observed after repeated dosing with ATACs regardless of the target or antibody. In the present study, we demonstrate the effect of ATAC pre-treatment on tolerability in pre-clinical models. Material and Methods: Antibody: Engineered monoclonal antibodies produced at Heidelberg Pharma Toxic warhead: Cysteine reactive amanitin-linker constructs were synthesized at Heidelberg Pharma and conjugated site-specifically to the antibody. Animal models: Tolerability in CB17 Scid mice and Cynomolgus monkeys; Efficacy in a subcutaneous LNCaP prostate cancer model; Treatment: ADC (ATAC): escalating dosing i.v. q21d (tolerability) or repeated dosing i.v. q7dx4 (efficacy). Results: The impact of repeated dosing on the tolerability of a non-targeting ATAC was tested in CB17 Scid mice. The mice were initially treated with the maximal tolerated dose (MTD) of an ATAC, or PBS followed by a second higher dose 21 days after the first dose. Pre-treatment improved the tolerability of a second, higher dose of the same non-targeting ATAC from 12.5% to 80% survival. As ATAC toxicity is mainly caused by liver toxicity, the liver damage markers AST, ALT and LDH are used as toxicity markers in non-human primate studies. The induction of liver damage markers observed after repeated or escalated dosing was significantly lower than the induction after single or first dose treatment. Taken together, these data indicate that ATAC treatment can induce tolerability in animal models. Furthermore, in a subcutaneous LNCaP prostate cancer model, multiple ATAC dosing did improve the anti-tumor efficacy as compared to single dose treatment, indicating that the induced tolerability is not associated with reduced anti-tumor efficacy. Conclusions: ATAC pre-treatment induces tolerability in preclinical animal models without a loss in efficacy. Since this effect of ATAC pre-treatment was observed across different animal species, it likely translates also into humans. Consequently, if reduced liver toxicity and less adverse effects after repeated dosing with ATACs are also observed in the upcoming clinical trials, it might have a significant impact on treatment regimen and clinical success of ATACs. Citation Format: Kristin Decker, Marisa Schmitt, Can Araman, Franziska Ebeling, Irina Dranova, Torsten Hechler, Anikó Pálfí, Andreas Pahl, Michael Kulke. Treatment with antibody-targeted amanitin conjugates induces tolerability in preclinical models without triggering tolerance [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1761.