Dissertations / Theses on the topic 'Astragalus'
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Chouana, Toufik. "Caractérisation structurale et activités biologiques des polysaccharides d'Astragalus gombo bunge." Thesis, Université Clermont Auvergne (2017-2020), 2017. http://www.theses.fr/2017CLFAC112/document.
Full textAstragalus gombo Bunge (Fabaceae) is a terrestrial plant occuring in the East Septentrional Sahara (Ouargla, Algeria). It is commonly used as fodder or in traditional medicine by local populations. Despite numerous publications focusing on polysaccharidic contents of Astragalus species and the designation of their putative or proved biological activities, no study has examined those of A. gombo. The objective of this thesis was firstly to investigate several organs of this plant for their polysaccharide contents. In a second step, the biological and rheological properties of these biopolymers have been studied to identify ways of adding value. Results led to the identification of pectic compounds and hemicelluloses in the rods of Astragalus gombo whereas a galactomannan was detected in its seeds. This galactomannan was a high molecular weight macromolecule composed of a β-(1→4)-D-mannan skeleton ramified by residues of D-galactopyranoses. The M/G ratio was of 1.7. The characterization of its rheological behavior was typic of that of a rheofluidifiant fluid with viscoelastic properties. The study of its biological properties showed its potential as prebiotic and antioxidant agent
Wang, Meili Shannon Dennis Alan. "Cultivation practices for Astragalus membranaceus in the southeastern United States." Auburn, Ala, 2009. http://hdl.handle.net/10415/1640.
Full textCabannes, Emmanuelle. "Sulphate transporters and selenium accumulation in Astragalus." Thesis, University of Nottingham, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546495.
Full textDizkirici, Ayten. "Evolutionary Relationships Among Astragalus Species Native To Turkey." Phd thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614427/index.pdf.
Full text-L3&rsquo
) , trnL3&rsquo
-F(GAA) (trnL-F intergenic spacer), trnV intron, matK (maturase kinase) cpDNA (chloroplast) and ITS (internal transcribed spacer) nDNA (nuclear) regions. Fifty-six Astragalus species with their replicas and one Cicer species as outgroup were analyzed by polymerase chain reaction amplification and DNA sequencing methods. Eleven unknown samples were also used in the current study to understand their section and species name. The results of the study indicated that unknown A35 and A52 samples could be named as A. dasycarpus, while unknown A65 and A66 samples as A. ovatus and lastly unknown A2 sample as A. nitens or A. aucheri. Section of unknown A3, A16, A20, A108, A109 and A110 samples were determined as Incani, but the exact species identification of these samples were not possible because of their close phylogenetic associations with more than one species. Highest genetic diversity was observed when the DNA sequences of ITS nrDNA (nuclear ribosomal) region comprising three subregions as ITS1, 5.8S and ITS2 was used, while the lowest one was calculated when DNA sequence of trnL-F cpDNA region was analyzed. The genetic divergence between Incani and Dissitiflori sections was highest whereas between Hypoglottidei and Dissitiflori was lowest based on all used regions. To figure out phylogenetic relationships among Astragalus species distributed in Turkey and in other regions of the World, DNA sequences of studied regions of foreign samples were collected from the NCBI database and were evaluated with DNA sequence of Turkish species used in the curent study. The Iranian samples either scattered in the phylogenetic tree or attached to our samples externally. South and North American samples (New World Astragalus or Neo Astragalus group) were nested within a different subcluster, which was located in the main cluster produced by samples of Old World Astragalus group (Turkish samples). With these results, we can say that New World Astragalus group is monophyletic and diverged from Old World Astragalus group. Evolutionary divergence time for Astragalus genus was estimated as about 12.5 - 14.5 million years (Ma), and that of New World Astragalus group as 5.0 - 4.0 Ma when rates of nucleotide substitutions of trnL intron and matK cpDNA regions were analyzed. In addition to evolutionary divergence time estimation for Astragalus and New World Astragalus group, divergence times among used three sections of the genus were also calculated by using DNA sequences of trnL, trnV intron and matK cpDNA regions and results indicated that Hypoglottidei and Dissitiflori sections diverged about 5.0-7.0 million years later than Incani section.
Law, Pui Ching. "Study of the modulating effects of Astragalus saponins on tumor angiogenesis and invasiveness in colon cancer cells." HKBU Institutional Repository, 2010. http://repository.hkbu.edu.hk/etd_ra/1156.
Full textSanderson, Michael John. "Patterns of homoplasy in North American Astragalus L. (Fabaceae)." Diss., The University of Arizona, 1989. http://hdl.handle.net/10150/184764.
Full textWatrous, Kristal M. "Reproductive Ecology of Astragalus filipes, a Great Basin Restoration Legume." DigitalCommons@USU, 2010. https://digitalcommons.usu.edu/etd/617.
Full text周穎茵. "黃芪多糖的化學組成及其對免疫系統調節作用的探討." HKBU Institutional Repository, 2017. https://repository.hkbu.edu.hk/etd_oa/453.
Full textWatson, Robert James. "Isolation and characterisation of the potential immunomodulatory principles from Astragalus membranaceus." University of Southern Queensland, Faculty of Sciences, 2006. http://eprints.usq.edu.au/archive/00004786/.
Full textWong, Daniella Pui Kwan. "Investigation of the role of GRP78 and the potential therapeutic use of radix astragali in diabetic complications." HKBU Institutional Repository, 2013. http://repository.hkbu.edu.hk/etd_ra/1546.
Full textZarre-Mobarakeh, Shahin. "Systematic revision of Astragalus sect. Adiaspastus, sect. Macrophyllium and Pterophorus (Fabaceae) /." [S.l. : s.n.], 1998. http://www.gbv.de/dms/bs/toc/253246628.pdf.
Full textSiegwarth, Mark. "Boyce Thompson Arboretum and Desert Legume Program's Search for the Wild Astragalus." University of Arizona (Tucson, AZ), 2011. http://hdl.handle.net/10150/556801.
Full textВисоцький, Ігор Юрійович, Игорь Юрьевич Высоцкий, Ihor Yuriiovych Vysotskyi, V. I. Vysotsky, Алла Анатоліївна Качанова, Алла Анатольевна Качанова, Alla Anatoliivna Kachanova, and A. V. Azhar. "The use of astragalus dasyanthus for prevention and treatment of toxic hepatopathy." Thesis, Sumy State University, 2016. http://essuir.sumdu.edu.ua/handle/123456789/45120.
Full textSemmar, Nabil. "Analyse de la diversité chimique (flavonoïdes et saponines) de l'espèce Astragalus caprinus (fabaceae)." Lyon 1, 2000. http://www.theses.fr/2000LYO10244.
Full textAbdel, Samad Farah. "Caractérisation écogéographique et génétique du genre Astragalus du Liban : approches de conservation biogéographique." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4320.
Full textThe genus Astragalus L. (Fabaceae) is one of the genera with the largest number of representatives among the angiosperms. Its center of origin and diversity is located in the arid mountains of Central and Southwest Asia. In Lebanon, this genus is also one of the most represented genera in the flora, with 62 species and subspecies and 22 endemic species identified. The different taxa of this genus are difficult to identify based only on morphological characters and their current status of distribution must be evaluated. Phylogenetic relationships, changes in genome size and the role of polyploidy in the evolution of Astragalus genus in the Lebanese mountains range were studied. Our data confirm that a significant interspecific chromosomal polymorphism exists in the genus Astragalus of Lebanon and polyploidy and the subsequent evolution of the genome may be important drivers of the evolution of this genus. The diversification process of Astragalus genus that took place in Lebanon was analyzed using phylogenetic and molecular dating methods and analysis of ancestral areas. Our results confirm that Lebanon is the third center of diversity and should be considered as a "cradle" of biodiversity. Therefore, this study is a contribution to a better understanding of evolutionary and biogeographic processes behind the development of biodiversity in Lebanon, with an applied purpose of biogeographic conservation
Eldredge, Sean D. "Beneficial fungal interactions resulting in accelerated germination of Astragalus utahensis, a hard-deeded legume /." Diss., CLICK HERE for online access, 2007. http://contentdm.lib.byu.edu/ETD/image/etd2206.pdf.
Full textLiu, Jing. "Comparative study on the chemical constituents and bioactivity between radix astragali and radix hedysari." HKBU Institutional Repository, 2011. https://repository.hkbu.edu.hk/etd_ra/1401.
Full textWalker, George Floyd. "Analysis of molecular variation in the federally endangered Astragalus jaegerianus (Fabaceae, Papilionoideae): A species with a restricted geographic range." CSUSB ScholarWorks, 2005. https://scholarworks.lib.csusb.edu/etd-project/2743.
Full textEldredge, Sean D. "Beneficial Fungal Interactions Resulting in Accelerated Germination of Astragalus utahensis, a Hard-Seeded Legume." BYU ScholarsArchive, 2007. https://scholarsarchive.byu.edu/etd/1231.
Full textTin, Man Ying. "Study of the anticarcinogenic mechanisms of astragalus membranaceus in colon cancer cells and tumor xenograft." HKBU Institutional Repository, 2006. http://repository.hkbu.edu.hk/etd_ra/777.
Full textLiu, Wing-yee, and 廖穎宜. "Effects of bioactive constituents of Astragalus membranaceus on the proliferation of colon cancer and endothelial cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206745.
Full textpublished_or_final_version
Pharmacology and Pharmacy
Master
Master of Philosophy
Kada, Abderrazik. "Contribution à l'étude biosystématique de quelques espèces du genre Astragalus L. (Papilionaceae) du Bassin méditerranéen occidental." Toulouse 3, 1991. http://www.theses.fr/1991TOU30257.
Full textZhang, Zhu. "Exploration of the anticancer mechanisms of novel chemotherapeutic adjuvants involving autophagy and immune system reprogramming in the treatment of pancreatic cancer." HKBU Institutional Repository, 2020. https://repository.hkbu.edu.hk/etd_oa/755.
Full textDeng, Ruixia, and 邓瑞霞. "Astragaloside IV promotes haematopoiesis and enhances cytokines release by mesenchymal stromal cells mediated immune regulation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hdl.handle.net/10722/198839.
Full textpublished_or_final_version
Chinese Medicine
Doctoral
Doctor of Philosophy
Barghi, Nasrine. "Les différents niveaux de la variabilité caryotypique et morphologique (développement hétéroblastique) dans les genres Glycyrrhiza L. Et Astragalus L." Paris 11, 1985. http://www.theses.fr/1985PA112356.
Full textThe present study, concerning three species of Glycyrrhiza (G. Echinata, G. Glabra –truth liquorice, G. Lepidota) and A. Glycyphyllos (falsehood liquorice) has permitted at different levels (species, populations, individuals, organs) to show and study two types of variations: karyotypical (for example, possible existence of chromosomical mosaic in some individual of A. Glycyphyllos) and morphological (speed and intensity of this developmental heterophylly, phenomenon of rejuvenation accompanied by ramification). The synthesis of our results has allowed us to order the species from the less to the more developed: G. Lepidota, G. Glabra, G. Echinata and A. Glycyphyllos. More fundamentally, the study of the speed and diversity of developmental heterophylly sequence has been shown of great relevance to taxonomic and phylogenic research
Sokoloff, Paul C. "Taxonomic status of the narrow endemic Astragalus robbinsii var fernaldii (Fernald's Milkvetch - Fabaceae): molecules, morphology, and implications for conservation." Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28671.
Full textWei, Lai, and 魏来. "Induction of LTB4 12-hydroxydehydrogenase (LTB4DH) by Radix Astragali and Radix Paeoniae Rubra: a study of theactive compounds and related biological functions." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B44683443.
Full textHaruda, Ashleigh Francis. "Central Asian economies and ecologies in the Late Bronze Age : geometric morphometrics of the caprid Astragalus and zooarchaeological investigations of pastoralism." Thesis, University of Exeter, 2014. http://hdl.handle.net/10871/17496.
Full textCano, Castillo Miriam. "Aplicación de la micropropagación y criopreservación a la conservación ex situ de especies vegetales de interés." Doctoral thesis, Universidad de Alicante, 2013. http://hdl.handle.net/10045/35678.
Full textSearle, Allyson B. "Reproductive Success and Soil Seed Bank Characteristics of Astragalus ampullarioides and A. holmgreniorum (Fabaceae): Two Rare Endemics of Southwestern Utah." BYU ScholarsArchive, 2011. https://scholarsarchive.byu.edu/etd/3044.
Full textJara, Peña Enoc Efer. "Evaluación de Lupinus condensiflorus C.P.Sm., L. ballianus C.P. Sm. y Astragalus garbancillo Cav. (Fabaceae) en la restauración de suelos que contienen plomo, cadmio y zinc." Doctoral thesis, Universidad Nacional Mayor de San Marcos, 2018. https://hdl.handle.net/20.500.12672/9406.
Full textTesis
Fund, Adam J. "Novel Treatments for Native Forb Restoration in The Great Basin." DigitalCommons@USU, 2018. https://digitalcommons.usu.edu/etd/7010.
Full textZhou, Rui Na. "Pharmacokinetic study of astragaloside IV, a saponin marker of Astragali Radix, and its intestinal bacterial metabolites in the rat." Thesis, University of Macau, 2012. http://umaclib3.umac.mo/record=b2590315.
Full textREVILLION, DOMINIQUE. "Les fractures de l'astragale : a propos de 33 cas." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20298.
Full textHu, Guang. "Pharmacological characterization of angiogenesis effect of Astragali Radix." Thesis, University of Macau, 2012. http://umaclib3.umac.mo/record=b2586303.
Full textTERNIER, FREDERIC. "Exploration tomodensitometrique des fractures de l'astragale." Aix-Marseille 2, 1991. http://www.theses.fr/1991AIX20813.
Full textCarrié, Didier. "Les luxations sous-astragaliennes : a propos de 34 cas." Amiens, 1994. http://www.theses.fr/1994AMIEM117.
Full textLin, Hui Chao. "Proangiogenic effect of Angelica sinensis, Radix Astragali and Radix notoginseng in zebrafish." Thesis, University of Macau, 2006. http://umaclib3.umac.mo/record=b1636291.
Full textHu, Guang. "Quantitative determination of six flavones and saponins in Radix Astragali by HPLC-ELSD." Thesis, University of Macau, 2006. http://umaclib3.umac.mo/record=b1636287.
Full textWei, Wei. "Immunomodulating effects of natural polysaccharides isolated from astragali radix and dendrobii officinalis caulis /Wei Wei." HKBU Institutional Repository, 2016. https://repository.hkbu.edu.hk/etd_oa/350.
Full textZhang, Yi. "The proangiogenic effect of Radix Astragali extract and astragaloside IV in human umbilical vein endothelial cells (HUVEC)." Thesis, University of Macau, 2007. http://umaclib3.umac.mo/record=b1676783.
Full textDalpizolo, Cristiano Antonio. "Estudo analítico da presença de astragalina em cultivares de feijão phaseolus vulgaris l." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/139393.
Full textPlants belonging to the legume family have a big economic interest, being Brazil is a country with extensive use of plants in this family. In this context, we highlight the legume Phaseolus vulgaris L. popularly known as beans, which are a good source of bioactive compounds. This species is native of southern Brazil and the main food consumed by the population. In its chemical composition can meet the flavonoids. Numerous scientific articles describing the activities of flavonoids as antioxidants, antimutagênic, anticarcinogenic and nitrogen uptake during plant development. Since this is a legume consumed more food in the world and of great economic importance, this study sought to evaluate the chromatographic profile of the methanol extract of 47 cultivars of beans through the technique of High Performance Liquid Chromatography (HPLC) and also the validation of their method. The plant material, seeds, water content was established by gravimetric method. Through the chromatographic profile of the seeds of bean cultivars, it was possible to identify the presence of flavonoids and astragalin, a kaempferol heteroside. The method was validated for High Performance Liquid Chromatography (HPLC) according to the methods suggested in the literature. The cultivars with colored TB 0224, TB0226, TB 0309, Rosinha Precoce and Amarelo Iolanda, were those with a higher content of astragalin, demonstrating that colored beans have a higher composition of astragalin.
Giacchè, Edoardo. "Pianificazione e progettazione in-silico di interventi di protesi totale di caviglia: definizione e valutazione di diversi approcci anatomici e disegni “su misura”." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017.
Find full textZierau, Oliver, Ken Y. Z. Zheng, Anja Papke, Tina T. X. Dong, Karl W. K. Tsim, and Günter Vollmer. "Functions of Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, in Uterus and Liver are Both Estrogen Receptor-Dependent and -Independent." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-165221.
Full textZierau, Oliver, Ken Y. Z. Zheng, Anja Papke, Tina T. X. Dong, Karl W. K. Tsim, and Günter Vollmer. "Functions of Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, in Uterus and Liver are Both Estrogen Receptor-Dependent and -Independent." Hindawi Publishing Corporation, 2014. https://tud.qucosa.de/id/qucosa%3A28666.
Full textLin, Yu Jin, and 林郁進. "Pharmcolognostical studies on Huangqi (Astragali Radix) and tissue-culture of Astragalus membranaceus." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/45890367704549509316.
Full textSager, Ricardo Luis. "Estudio químico-toxicológico de Astragalus distinens Macloskie y Astragalus bergii Hieronimus." Tesis, 1985. http://hdl.handle.net/10915/1526.
Full textThe study on Astragalus distinens Macloskie and Astragalus bergii Hieronimus arises from the necessity of giving a solution to the problems of poisoning in bovine and ovine that are produced yearly in the southern part of the San Luis Province. The species that was identified as the cause of these problems is A. distihens, but A. bergii has been included because both species share the same distribution area and also because both of them are quite similar. The search for its toxic compounds was done on the basis of the information reviewed, that they havehydrocianic acid, saponins and selenium. Also aliphatic nitrocompounds, that were identified in various Astragalus species from abroad, were included.
Alexander, J. Andrew. "A taxonomic revision of Astragalus mokiacensis and allied taxa within the Astragalus lentiginosus complex of Section Diphysi /." 2007. http://hdl.handle.net/1957/8118.
Full text"Immunomodulatory and anti-tumour activities of Astragalus membranaceus." Chinese University of Hong Kong, 1991. http://library.cuhk.edu.hk/record=b5886879.
Full textThesis (M.Phil.)--Chinese University of Hong Kong, 1991.
Includes bibliographical references.
Acknowledgements --- p.I
Table of Contents --- p.II
Abbreviations --- p.VII
Aim and Scope of This Dissertation --- p.X
Abstract --- p.XII
Chapter Chapter One --- General Introduction --- p.1
Chapter 1.1 --- An Overview of the Immune System --- p.1
Chapter 1.1.1 --- Humoral antibody immune responses --- p.2
Chapter 1.1.2 --- Cell-mediated immune responses --- p.3
Chapter 1.2 --- Immunomodulation --- p.4
Chapter 1.3 --- An Overview of the Anti-tumour Strategies --- p.6
Chapter 1.3.1 --- Immunological defense mechanisms against tumours --- p.8
Chapter 1.3.1.1 --- T and B lymphocytes --- p.9
Chapter 1.3.1.2 --- The monocytes/macrophages --- p.9
Chapter 1.3.1.3 --- Non-specific killer cells --- p.10
Chapter 1.3.2 --- Adoptive immunotherapy against tumours --- p.11
Chapter 1.3.3 --- Induction of tumour cell differentiation --- p.12
Chapter 1.4 --- Traditional Chinese Medicines as Potential Immunomodulators and Anti-tumour Agents --- p.13
Chapter 1.5 --- General Properties of Astragalus membranaceus --- p.16
Chapter Chapter Two --- Materials and Methods --- p.20
Chapter 2.1 --- Materials --- p.20
Chapter 2.1.1 --- Animals --- p.20
Chapter 2.1.2 --- Astragalus membranaceus --- p.20
Chapter 2.1.3 --- "Buffers, culture media and chemicals" --- p.20
Chapter 2.1.4 --- Cell lines --- p.25
Chapter 2.2 --- Methods --- p.28
Chapter 2.2.1 --- Extraction and fractionation of Astragalus membranaceus --- p.28
Chapter 2.2.2 --- Characterization of Astragalus membranaceus --- p.32
Chapter 2.2.3 --- In vivo drug treatment --- p.33
Chapter 2.2.4 --- Isolation and preparation of cells --- p.34
Chapter 2.2.5 --- Assays for the immunomodulatory activities of Astragalus membranaceus --- p.36
Chapter 2.2.6 --- Assays for the immunorestorative properties of Astragalus membranaceus --- p.42
Chapter 2.2.7 --- Assays for the anti-tumour activities of Astragalus membranaceus --- p.43
Chapter 2.2.8 --- Statistical analysis --- p.47
Chapter Chapter Three --- "Extraction, Fractionation and Characterization of Bioactive Components from Astragalus membranaceus" --- p.49
Introduction --- p.49
Results --- p.50
Chapter 3.1 --- Extraction and Fractionation of Astragalus membranaceus --- p.50
Chapter 3.2 --- Lack of Cytotoxicity of A.M. to Mouse Splenocytes --- p.51
Chapter 3.3 --- Mitogenic Effect of A.M. Fractions on Mouse Splenocytes --- p.51
Chapter 3.4 --- AP and AI Fractions Did Not Exhibit Lectin-like Activity --- p.52
Chapter 3.5 --- Heat Stability of AP and AI Fractions --- p.52
Chapter 3.6 --- Chemical Destruction of the Mitogenic Activity of AI by Sodium Periodate But Not by Acetic Acid Treatment --- p.53
Discussion --- p.54
Chapter Chapter Four --- The Immunomodulatory Activities of Astragalus membranaceus --- p.63
Introduction --- p.63
Results --- p.65
Chapter 4.1 --- Effect of Astragalus membranaceus on the Specific and Nonspecific Immunity --- p.65
Chapter 4.1.1 --- Mitogenic effect of AI on mouse splenocytes in vivo --- p.65
Chapter 4.1.2 --- Effect of AI on lymphocyte sub-populations --- p.66
Chapter 4.1.3 --- Co-mitogenic effect of AI on mouse splenocytes in vitro --- p.66
Chapter 4.1.4 --- Enhancement of the mitogen-induced lymphocyte transformation in vitro by oral administration of AI --- p.67
Chapter 4.1.5 --- Mitogenic and co-mitogenic effects of AI on human cord blood lymphocytes in vitro --- p.67
Chapter 4.1.6 --- Primary humoral immune response to SRBC in AI-treated mice --- p.68
Chapter 4.1.7 --- Effect of AI on interleukin-2 production --- p.68
Chapter 4.1.8 --- Effect of AI on interleukin-2 receptor expression on mouse splenocytes --- p.69
Chapter 4.1.9 --- Immunopotentiating effects of AI on macrophage functions --- p.70
Chapter 4.1.9.1 --- Effect of AI on the cytostatic activity of macrophages in vitro --- p.70
Chapter 4.1.9.2 --- In vivo migration and phagocytic activity of macrophages in AI-treated mice --- p.70
Chapter 4.1.9.3 --- Cytostatic activity of macrophages in AI-treated mice --- p.71
Chapter 4.1.9.4 --- Effect of AI on the Fc receptor expression on mouse resident peritoneal exudate cells --- p.71
Chapter 4.2 --- Immunorestorative Properties of Astragalus membranaceus --- p.72
Chapter 4.2.1 --- Effect of AI on lymphocyte blastogenesis in aging mice --- p.72
Chapter 4.2.2 --- Effect of AI on lymphocyte blastogenesis in tumour-bearing mice --- p.72
Chapter 4.2.3 --- Effect of AI on lymphocyte blastogenesis in cyclophosphamide- treated mice --- p.73
Discussion --- p.74
Chapter Chapter Five --- The Anti-tumour Activities of Astragalus membranaceus --- p.94
Introduction --- p.94
Results --- p.95
Chapter 5.1 --- Lack of Direct Cytotoxicity of AI to Murine and Human Tumour Cell Lines In Vitro --- p.95
Chapter 5.2 --- Cytostatic Effect of AI on Various Murine and Human Cell Lines In Vitro --- p.96
Chapter 5.3 --- Effect of AI on the Growth of Transplantable Tumour Cells In Vivo --- p.97
Chapter 5.4 --- Effect of AI on TNF Production in Tumour-bearing Mice --- p.97
Chapter 5.5 --- In Vitro Induction of Lymphokine-activated Killer Cell Activity by AI --- p.98
Chapter 5.6 --- Tumour Cell Differentiation-inducing Activity of AI --- p.99
Discussion --- p.100
Chapter Chapter Six --- General Discussion and Future Perspectives --- p.120
References --- p.130
Chien, Yung-Liang, and 簡永亮. "Studies on Antioxidative Components from Seeds of Astragalus complantus, Flowers of Lanata camara, and Volatile Components from Seeds of Astragalus complantus." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/63519975804874872526.
Full text東海大學
食品科學系
88
The purposes of this study were to investigate antioxidative components from seeds of Astragalus complantus and flowers of Lanata camara and volatile components from seeds of Astragalus complantus. The results were summerized as following: (1) The antioxidative components from the ethyl acetate extract of seeds of Astragalus complantus The ground powder of seeds of Astragalus complantus was extracted with methanol . Then the methanol extract was extracted with n-hexane, ethyl acetate and n-butanol in succession. The antioxidative activity of the extracts was measured by the ferric thiocyanate method. The antioxidative efficiency was found in following order : BHA>ethyl acetate extract>n-butanol extract>α-tocopherol>n-hexane extract>control. The ethyl acetate extract was fractionated by various chromatographies to isolate three pure components. Two of the isolated components were identified to be 3,5-dihydroxy-4''-methoxy- 1,1''-(1''2-ethylenediyl) bis[benzene] and 6''-methoxy-7-methyl formononetin (7,4'',6''-trimethoxy isoflavone) respectively.The rest one was tentatively concluded to be p-coumaroyl triterpenoid ester. (2) The antioxidative components from the ethyl acetate extract of flower of Lanata camara The flowers of Lanata camara were extractd with n-hexane, ethyl acetate, chloroform and methanol in order. The antioxidative activity of extracts were measured by the ferric thiocyanate method. The antioxidative efficiency was found in following order : BHA>ethyl acetate extract>α-tocopherol>n-hexane extract>methanol extract>chloroform extract>control. The ethyl acetate extract was fractionated by various chromatographies to isolate two pure polyphenyl. They were identified to be 2''-(3",4",5"- trihydroxyphenyl)-ethyl -sterate and protocatechuic acid respectively. (3)Volatile components from seeds of Astragalus complantus The volatile extracts were obtained from seeds of Astragalus complantus by Likens-Nickerson extraction, supercritical fluid extraction (SFE) and the ethyl acetate extract. The 28 components of the volatile extracts had been identified by GC-MS,including 5 alkylenes, 5 aldehydes, 5 ketones, 5 acids, 3 esters and 1 alkane. The antioxidative activities of the volatile extracts and solvents extracts were analyzed by the ferric thiocyanate method and compared to that of BHA and α-tocopherol. The antioxidative activity of the ethyl acetate extraction was found to be better than those of Likens-Nickerson extraction and supercritical fluid extraction.