Academic literature on the topic 'Asthma – Hormone therapy'

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Journal articles on the topic "Asthma – Hormone therapy"

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Bossios, Apostolos. "Hormone Replacement Therapy and Asthma." Chest 160, no. 1 (July 2021): 3–4. http://dx.doi.org/10.1016/j.chest.2021.03.020.

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Edwards, Alun L., M. Sarah Rose, Lois E. Donovan, and Gordon T. Ford. "Premenstrual Exacerbation of Life-Threatening Asthma: Effect of Gonadotrophin Releasing Hormone Analogue Therapy." Canadian Respiratory Journal 3, no. 3 (1996): 203–6. http://dx.doi.org/10.1155/1996/691249.

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Variability in the severity of asthma during various phases of the menstrual cycle has been frequently suspected. However, the hormonal changes that might affect mediators of bronchospasm have yet to be elucidated. The case of a 41-year-old woman suffering from longstanding asthma with life-threatening exacerbations is reported. The patient was treated with buserelin, a gonadotropin releasing hormone (GnRH) analogue, which created a temporary chemical menopause and thus permitted diagnosis of a premenstrual exacerbation of asthma and offered insight into potential therapy. GnRH analogues may therefore be of value in assessing women with severe asthma suspected to vary with the menstrual cycle. The addition of estrogens and progestins at the same time as treatment with GnRH analogue may be of value in determining the role of these hormones in the pathogenesis of menstrually related exacerbations of asthma.
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SMITH, JENNIE. "Estrogen-Only Hormone Therapy Linked to Asthma." Family Practice News 40, no. 4 (March 2010): 38. http://dx.doi.org/10.1016/s0300-7073(10)70358-3.

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Bønnelykke, Klaus, Ole Raaschou-Nielsen, Anne Tjønneland, Charlotte Suppli Ulrik, Hans Bisgaard, and Zorana Jovanovic Andersen. "Postmenopausal hormone therapy and asthma-related hospital admission." Journal of Allergy and Clinical Immunology 135, no. 3 (March 2015): 813–16. http://dx.doi.org/10.1016/j.jaci.2014.11.019.

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Hansen, Erik Soeren Halvard, Kristian Aasbjerg, Amalie Lykkemark Moeller, Elisabeth Juul Gade, Christian Torp-Pedersen, and Vibeke Backer. "Hormone Replacement Therapy and Development of New Asthma." Chest 160, no. 1 (July 2021): 45–52. http://dx.doi.org/10.1016/j.chest.2021.01.054.

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Baldaçara, Raquel Prudente de Carvalho, and Ivaldo Silva. "Association between asthma and female sex hormones." Sao Paulo Medical Journal 135, no. 1 (January 5, 2017): 4–14. http://dx.doi.org/10.1590/1516-3180.2016.011827016.

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ABSTRACT CONTEXT AND OBJECTIVE: The relationship between sex hormones and asthma has been evaluated in several studies. The aim of this review article was to investigate the association between asthma and female sex hormones, under different conditions (premenstrual asthma, use of oral contraceptives, menopause, hormone replacement therapy and pregnancy). DESIGN AND SETTING: Narrative review of the medical literature, Universidade Federal do Tocantins (UFT) and Universidade Federal de São Paulo (Unifesp). METHODS: We searched the CAPES journal portal, a Brazilian platform that provides access to articles in the MEDLINE, PubMed, SciELO, and LILACS databases. The following keywords were used based on Medical Subject Headings: asthma, sex hormones, women and use of oral contraceptives. RESULTS: The associations between sex hormones and asthma remain obscure. In adults, asthma is more common in women than in men. In addition, mortality due to asthma is significantly higher among females. The immune system is influenced by sex hormones: either because progesterone stimulates progesterone-induced blocking factor and Th2 cytokines or because contraceptives derived from progesterone and estrogen stimulate the transcription factor GATA-3. CONCLUSIONS: The associations between asthma and female sex hormones remain obscure. We speculate that estrogen fluctuations are responsible for asthma exacerbations that occur in women. Because of the anti-inflammatory action of estrogen, it decreases TNF-α production, interferon-γ expression and NK cell activity. We suggest that further studies that highlight the underlying physiopathological mechanisms contributing towards these interactions should be conducted.
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Romieu, I., A. Fabre, A. Fournier, F. Kauffmann, R. Varraso, S. Mesrine, B. Leynaert, and F. Clavel-Chapelon. "Postmenopausal hormone therapy and asthma onset in the E3N cohort." Thorax 65, no. 4 (February 8, 2010): 292–97. http://dx.doi.org/10.1136/thx.2009.116079.

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Lange, P., J. Parner, E. Prescott, C. Suppli Ulrik, and J. Vestbo. "Exogenous female sex steroid hormones and risk of asthma and asthma-like symptoms: a cross sectional study of the general population." Thorax 56, no. 8 (August 1, 2001): 613–16. http://dx.doi.org/10.1136/thx.56.8.613.

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BACKGROUNDRecent evidence suggests a role for hormonal factors in the aetiology of asthma.METHODSData from a large study of women selected from the general population were used to relate treatment with oral hormonal contraceptives (OCP) and postmenopausal hormone replacement therapy (HRT) to the following asthma indicators: self-reported asthma, wheezing, cough at exertion, and use of medication for asthma. The study sample comprised 1536 premenopausal and 3016 postmenopausal women who participated in the third round of the Copenhagen City Heart Study in 1991–4. A total of 377 women were taking OCP (24.5% of premenopausal women) and 458 were on HRT (15.2% of postmenopausal women).RESULTSIn premenopausal women 4.8% reported having asthma. The prevalence of self-reported asthma, wheeze, use of asthma medication, and cough at exertion was not significantly related to use of OCP. In postmenopausal women the prevalence of self-reported asthma was 6.2%. A weak but consistent association was observed between HRT and self-reported asthma (OR 1.42 (95% CI 0.95 to 2.12)), wheeze (OR 1.29 (95% CI 1.02 to 1.64)), cough at exertion (OR 1.34 (95% CI 1.01 to 1.77)), and use of asthma medication (OR 1.45 (95% CI 0.97 to 2.18)).CONCLUSIONSIn this study of the general population no relationship was found between the use of OCP and asthma. Although an association was observed between HRT and asthma and asthma-like symptoms, this was relatively weak and it is concluded that there is no necessity to change present prescription practice.
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Kuklina, G. M., I. V. Sivokozov, N. N. Makaryants, and E. I. Shmelev. "Successful Use of Bronchial Thermoplastics in a Female Patient with Severe Bronchial Asthma." Doctor.Ru 19, no. 11 (2020): 38–41. http://dx.doi.org/10.31550/1727-2378-2020-19-11-38-41.

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Objective: To describe the use of bronchial thermoplastics (BT) in a female patient with severe hormone-dependent bronchial asthma (BA). Key Points. Because of the history of unsuccessful use of the basic BA therapy and continuous inefficient use of the systemic glucocorticosteroids, the patient underwent a three-session BT. Her condition stabilised on day 5–6 following each BT session: shortness of breath retracted, stridor and sputum discharge disappeared. During a follow-up visit in 6 months, the patient had basic therapy (budesonide with formoterol (Symbicort) 160/4.5μg, 2 doses bid, methylprednisolone 4mg, once daily); she had no complains. The patient had vesicular respiration without stridor; forced expiratoty volume1 was 95%, lung capacity was 113%. Conclusion. Three BT sessions allowed minimising glucocorticosteroids dose, adjusting basic therapy and achieving long-term BA remission. Keywords: bronchial asthma, bronchial thermoplastics, glucocorticosteroids.
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АKULOVА, E. А., O. V. STEPАNOVА, O. V. LOVАCHEVА, А. А. SEYLIEV, K. G. SHАPOVАLOV, and O. А. ROZENBERG. "CHANGES IN HEMODYNAMICS DURING THE COURSE OF SURFACTANT THERAPY IN PATIENTS WITH HORMONE-DEPENDENT ASTHMA." TUBERCULOSIS AND LUNG DISEASES 97, no. 4 (2019): 25–29. http://dx.doi.org/10.21292/2075-1230-2019-97-4-25-29.

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Dissertations / Theses on the topic "Asthma – Hormone therapy"

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Zein, Joe Georges. "Gender Based Precision Care in Asthma." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1585768141945515.

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Herbert, Cristan Medical Sciences Faculty of Medicine UNSW. "Effects of glucocorticoid and phosphodiesterase-4 inhibitor therapy in a mouse model of chronic asthma." 2007. http://handle.unsw.edu.au/1959.4/40535.

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Asthma is a chronic inflammatory disease of the airways. Using a murine model which replicates many characteristic features of human asthma, this study evaluated the effects of treatment with anti-inflammatory drugs on the lesions of chronic asthma, and investigated potential underlying molecular mechanisms. Treatment with dexamethasone, a glucocorticoid, was compared with roflumilast, a novel phosphodiesterase-4 (PDE4) inhibitor. BALB/c mice sensitised to ovalbumin were challenged with a low mass concentration of aerosolised antigen for 30 min/day, 3 days/week for 6 weeks. In weeks 5 and 6, groups of animals were treated with either dexamethasone or roflumilast. Assessment included changes in acute-on-chronic inflammation, structural remodelling of the airways and airway hyper-responsiveness to a bronchoconstrictor stimulus. These were correlated with the expression of pro-inflammatory cytokines and growth factors. Compared to vehicle-treated control animals, dexamethasone- and roflumilast-treated mice exhibited reduced accumulation of intra-epithelial eosinophils and chronic inflammatory cells, including CD3+ T-lymphocytes in the airways. Similarly, both drugs inhibited subepithelial fibrosis and airway epithelial thickening, although only dexamethasone inhibited goblet cell hyperplasia/metaplasia. Airway hyper-reactivity was not diminished by either drug. Both treatments suppressed production of Th2 cytokines by ovalbumin-restimulated peribronchial lymph node cells. In selectively dissected airway tissue from vehicletreated animals, increased expression of mRNA for several pro-inflammatory cytokines (TNF-α, GM-CSF, IL-6) and cytokines characteristic of Th1 (IFN-γ), Th2 (IL-5, IL-13)and Th17 (IL-17A) cells was demonstrated using real-time PCR. Enhanced expression of growth factors (TGF-β1 and FGF-2) was also demonstrated in airway epithelium isolated by laser capture microdissection. Interestingly, whereas treatment with dexamethasone significantly inhibited expression of mRNA for all of the inflammationrelated cytokines examined, roflumilast inhibited only IL-17A, TNF-α, GM-CSF and IL-6. Both drugs inhibited mRNA expression of growth factors by epithelial cells. Because roflumilast was as effective as dexamethasone in suppressing inflammation and most changes of remodelling, the selective suppression of IL-17A, TNF-α, GM-CSF and IL-6 suggests that these mediators, or the cells that produce them, may have critical roles in pathogenesis. Furthermore, they may be particularly appropriate therapeutic targets in chronic asthma.
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Books on the topic "Asthma – Hormone therapy"

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Inhaled glucocorticoids in asthma: Mechanisms and clinical actions. New York: Dekker, 1997.

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(Editor), Robert P. Schleimer, William W. Busse (Editor), and Paul O'Byrne (Editor), eds. Inhaled Glucocorticoids in Asthma: Mechanisms and Clinical Actions (Lung Biology in Health and Disease). Informa Healthcare, 1997.

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Glucocorticoids and Mechanisms of Asthma: Clinical and Experimental Aspects: Proceedings of a Symposium in Toronto, 18-19 November 1988 (Current cli. Excerpta Medica, 1989.

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Glucocorticoids and mechanisms of asthma: Clinical and experimental aspects : proceedings of a symposium in Toronto, 18-19, November 1988. Amsterdam: Excerpta Medica, 1989.

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5

Barnes, Peter. Asthma Therapy. Taylor & Francis, 1998.

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1955-, Schachter Howard M., and Canadian Coordinating Office for Health Technology Assessment., eds. The challenges of early assessment: Leukotriene receptor antagonists. Ottawa, Ont: Canadian Coordinating Office for Health Technology Assessment, 2001.

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Conference papers on the topic "Asthma – Hormone therapy"

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Zhang, P., and J. G. Zein. "Menopausal Hormone Replacement Therapy and Risk of Asthma." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7089.

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Sören Halvard Hansen, Erik, Kristian Aasbjerg, Amalie Lykkemark Møller, Elisabeth Gade, Christian Torp-Pedersen, and Vibeke Backer. "Women receiving hormone replacement therapy are at high risk of developing asthma." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1430.

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