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Journal articles on the topic 'ASSESSING SEVERITY'

Author: Grafiati

Published: 11 September 2023

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1

Bain, P. G., L. J. Findley, P. Atchison, M. Behari, M. Vidailhet, M. Gresty, J. C. Rothwell, P. D. Thompson, and C. D. Marsden. "Assessing tremor severity." Journal of Neurology, Neurosurgery & Psychiatry 56, no. 8 (August 1, 1993): 868–73. http://dx.doi.org/10.1136/jnnp.56.8.868.

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2

Honey, Laura. "Assessing and grading BOAS severity." In Practice 43, no. 10 (December 2021): 547. http://dx.doi.org/10.1002/inpr.148.

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3

Halpin, David M. G. "Assessing the severity of COPD." Primary Care Respiratory Journal 15, no. 2 (April 1, 2006): 78–80. http://dx.doi.org/10.1016/j.pcrj.2005.12.005.

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4

Yi, Qing, Jinming Zhang, and Hua-Hua Chang. "Assessing CAT Test Security Severity." Applied Psychological Measurement 30, no. 1 (January 2006): 62–63. http://dx.doi.org/10.1177/0146621605280354.

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5

Teunisse, Saskia. "Assessing the Severity of Dementia." Archives of Neurology 48, no. 3 (March 1, 1991): 274. http://dx.doi.org/10.1001/archneur.1991.00530150042015.

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6

Cakal, Ergun. "Assessing (and Making Sense of) Severity." Nordic Journal of International Law 91, no. 2 (May 9, 2022): 284–309. http://dx.doi.org/10.1163/15718107-91020003.

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Abstract The element of severity remains core to the definition and interpretation of torture under international law. It has long represented a source of confusion and obfuscation for the legally-oriented anti-torture professional, whether academic, advocate or adjudicator. Its character as decisive differentiator, setting torture apart from cruelty, inhumanity and degradation, remains problematically entrenched and contested. It is a legal construct not finding its origins in the scholarship on pain, and evades precise measurement – as pain is socio-culturally constructed, relative and subjective. Accepting the prevailing complexity and addressing the perennial ambiguity, this article aims to offer some clarifications towards conceptualising and contextualising, and thereby better specifying and applying, torture’s core.

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7

Odemuyiwa, O., and R. J. Hall. "Assessing the severity of valve stenosis." Heart 55, no. 2 (February 1, 1986): 117–19. http://dx.doi.org/10.1136/hrt.55.2.117.

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8

Annibale, Bruno, and Edith Lahner. "Assessing the severity of atrophic gastritis." European Journal of Gastroenterology & Hepatology 19, no. 12 (December 2007): 1059–63. http://dx.doi.org/10.1097/meg.0b013e3282f198c2.

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9

Mansfield, Caroline S., Boyd R. Jones, and T. Spillman. "Assessing the severity of canine pancreatitis." Research in Veterinary Science 74, no. 2 (April 2003): 137–44. http://dx.doi.org/10.1016/s0034-5288(02)00181-9.

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10

Cairns, J. A., and K. M. Johnston. "Assessing the severity of depressive illness." Journal of Clinical Psychology 48, no. 4 (July 1992): 455–62. http://dx.doi.org/10.1002/1097-4679(199207)48:4<455::aid-jclp2270480405>3.0.co;2-z.

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11

Belousov, A. N. "NEW ALGORITHM FOR ASSESSING THE PATIENT’S SEVERITY." Clinical anatomy and operative surgery 16, no. 4 (November 23, 2017): 143–48. http://dx.doi.org/10.24061/1727-0847.16.4.2017.115.

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12

Aliyev, Aziz Sh, Bakhrambek I. Mukhamedov, Evelina V. Koldarova, and Umida A. Tashkenbaeva. "Comparison of methods for assessing acne severity." Vestnik dermatologii i venerologii 98, no. 3 (July 21, 2022): 61–69. http://dx.doi.org/10.25208/vdv1311.

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Background. Given today's standards of care, assessing the severity of acne is very important to the practicing dermatologist. Currently, there are many methods for assessing the severity of acne, however, there is no single generally accepted method of assessment that would satisfy the needs of the practitioner and the specialist researcher. Aims. The purpose of our study was to compare the two most commonly used methods for assessing the severity of acne the Global Acne Grading System (GAGS) and the Dermatological Acne Index (DIA) in order to select the most appropriate one for use in the daily practice of a dermatologist. Materials and methods. The study included 64 patients with acne who applied for an appointment with dermatologists at the consultative polyclinic of the Republican Dermovenereological Clinical Hospital for the period March June 2019. Of these, there were 26 men and 38 women 40.6% and 59.4%. All patients were assessed for the severity of acne by two methods GAGS and DIA by three researchers dermatologists. Results. In the course of the study, both among men and women, the vast majority of patients with acne were between the ages of 18 and 25 years. When examining patients using the GAGS index, 46.8% of patients were observed with mild severity, 39.1% with moderate and 14.1% with severe acne, with a significant difference only in severe acne between men and women (p 0.05). When assessing GAGS, more patients were observed with mild severity, and when assessing DIA, moderate severity. There was a good correlation (0.914) between the scores of the two acne severity scales. Conclusions. Considering that both methods for assessing the severity of acne showed approximately the same results, the method for assessing acne according to the DIA scale, due to the shorter time spent for its implementation, can be used in the daily practice of a dermatologist.

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13

Wilson, Robert F. "Assessing the Severity of Coronary-Artery Stenoses." New England Journal of Medicine 334, no. 26 (June 27, 1996): 1735–37. http://dx.doi.org/10.1056/nejm199606273342610.

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14

Lehmann, E. D. "Assessing the severity of carotid artery disease." Lancet 346, no. 8990 (December 1995): 1621. http://dx.doi.org/10.1016/s0140-6736(95)91949-x.

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15

Murthy, Srinivas, Gail Carson, Peter Horby, Laura Merson, and Steve Webb. "Clinical research networks and assessing pandemic severity." Lancet Global Health 7, no. 1 (January 2019): e33. http://dx.doi.org/10.1016/s2214-109x(18)30413-3.

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16

Charlson, Mary E., Frederic L. Sax, C. Ronald MacKenzie, Suzanne D. Fields, Robert L. Braham, and R. G. Douglas. "Assessing illness severity: Does clinical judgment work?" Journal of Chronic Diseases 39, no. 6 (January 1986): 439–52. http://dx.doi.org/10.1016/0021-9681(86)90111-6.

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17

Moran, Paul, and Mike J. Crawford. "Assessing the severity of borderline personality disorder." British Journal of Psychiatry 203, no. 3 (September 2013): 163–64. http://dx.doi.org/10.1192/bjp.bp.113.128249.

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SummaryThe identification of a reliable and valid severity index for borderline personality disorder has vexed researchers for decades. A simple, clinically intuitive severity index for borderline personality disorder with predictive validity has now been identified. This index could usefully guide treatment planning, but other contextual factors should also determine the need for specialist treatment.

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18

Rehman, Ansa Kulsoom, Humaira Taj Niazi, and Laila Bahadur. "Hematological Indicators Assessing Severity in Dengue Patients." Pakistan Journal of Medical and Health Sciences 16, no. 11 (November 30, 2022): 451–53. http://dx.doi.org/10.53350/pjmhs20221611451.

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Background: Dengue is viral disease of human transmitted by Aedes aegypti mosquito. The clinical signs and symptoms of dengue infection range significantly, from mild dengue fever to a severe illness. Objective: Our study aims to describe the potential predictive hematological parameters which are associated with severity in dengue patients. Methodology: This study was descriptive study conducted at the department of Pathology (Hematology), Maqsood Medical Complex and General Hospital, Peshawar, for duration of six months from 1st May 2022 to 31st October 2022. Blood samples were taken aseptically from all the included patients and were sent to the hospital diagnostic laboratory where the hematological parameters were determined. All the data was collected in a pre-designed proforma. The data analysis was done by using IBM SPSS version 23. Results: In the current study, a total of 160 patients were enrolled. There were 102 (63.75%) male patients while female patients were 56 (36.25%). Based on the hematological parameters, the mean (±SD) Hematocrit (%), Hemoglobin (g/dl), White cell count (/µL), Lymphocytes(/µL), Neutrophils (%) and Platelets (/µL) in non severe dengue cases vs severe dengue cases were 39.2 (±5.1)% vs 42.3 (±4.3)%, 12.5 (±0.9) g/dl vs 13.9 (±1.8) g/dl, 3290 (±1.4) /µL vs 4750 (±1.6) /µL, 40.6 (±12.19)/µL vs 46.1 (±9.96) /µL, 44.4 (±16.56)% vs 49.4 (±12.44) % and 10,5000 (±1.12) /µL vs 56,000 (±2.36)/µL respectively. Conclusion: Our study concludes that some common hematological markers have a substantial correlation with the severity of dengue illness. Keywords: Hematological indicators; severe dengue; Non-severe dengue

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19

Kulkarni, GirishBaburao. "Biomarkers in assessing the severity of stroke." APIK Journal of Internal Medicine 9, no. 3 (2021): 137. http://dx.doi.org/10.4103/ajim.ajim_57_21.

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20

Jha, Pawan Kumar. "A Comparative Study of Assessment of Different Parameters for Assessing Severity of Acute Pancreatitis." Journal of Medical Science And clinical Research 05, no. 06 (June 12, 2017): 23257–62. http://dx.doi.org/10.18535/jmscr/v5i6.76.

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21

Modasia, KhushbooH, and Feroze Kaliyadan. "Digital tools for assessing disease severity in dermatology." Indian Dermatology Online Journal 13, no. 2 (2022): 190. http://dx.doi.org/10.4103/idoj.idoj_636_21.

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22

Bos, René, Ashim Giyanani, and Wim Bierbooms. "Assessing the Severity of Wind Gusts with Lidar." Remote Sensing 8, no. 9 (September 14, 2016): 758. http://dx.doi.org/10.3390/rs8090758.

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23

MIZUKAMI, Yasushi, Morito KINJO, Naoji NAGAMINE, Yukihiro OKUHAMA, Takao KINJO, and Toru SUNAGAWA. "Assessing severity of patients with portal venous gas." Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 73, no. 5 (2012): 1049–53. http://dx.doi.org/10.3919/jjsa.73.1049.

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24

Boose, A., S. Spieker, C. Jentgens, T. Klockgether, E. Scholz, and J. Dichgans. "Assessing tremor severity with long-term tremor recordings." Journal of Neurology, Neurosurgery & Psychiatry 57, no. 3 (March 1, 1994): 397. http://dx.doi.org/10.1136/jnnp.57.3.397.

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25

Anzueto, A., PMA Calverley, RA Wise, A. Mueller, N. Metzdorf, and D. Dusser. "Assessing COPD profiles and outcomes by dyspnoea severity." Pneumologie 71, S 01 (February 23, 2017): S1—S125. http://dx.doi.org/10.1055/s-0037-1598544.

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26

Tural, Ümit, Hüray Fidaner, Tunc Alkin, and Borwin Bandelow. "Assessing the severity of panic disorder and agoraphobia:." Journal of Anxiety Disorders 16, no. 3 (January 2002): 331–40. http://dx.doi.org/10.1016/s0887-6185(02)00104-4.

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27

Pereira, Jose, Jose Paiva, and Jordi Rello. "Assessing Severity of Patients with Community-Acquired Pneumonia." Seminars in Respiratory and Critical Care Medicine 33, no. 03 (June 2012): 272–83. http://dx.doi.org/10.1055/s-0032-1315639.

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28

Lance Gould, K. "Assessing coronary stenosis severity—A recurrent clinical need." Journal of the American College of Cardiology 8, no. 1 (July 1986): 91–94. http://dx.doi.org/10.1016/s0735-1097(86)80096-1.

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29

Ashford, J. Wesson, Vinod Kumar, Mary Barringer, Marion Becker, Jami Bice, Nelly Ryan, and Sandra Vicari. "Assessing Alzheimer Severity With a Global Clinical Scale." International Psychogeriatrics 4, no. 1 (June 1992): 55–74. http://dx.doi.org/10.1017/s1041610292000905.

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Diagnosis of dementia needs to be complemented by precise determination of disease severity across the broad spectrum of disease progression. The Mini-Mental State Exam (MMS), the Activities-of-Daily-Living assessment (ADL) and the Clinical Dementia Rating scale (CDR) were modified for direct comparability and administred to 112 outpatients and 45 nursing home residents with a range of dementia severity from mild to profound. The scales showed the highest correlations for the probable Alzheimer's disease patient group (62) (Global Assessment of Dementia; GAD vs. ADL: r = 0.91; Extended Mini-Mental Assessment; EMA vs. GAD: r = 0.91; ADL vs. EMA: r = 0.86). For these patients, scores on the individual scales tended to be similar. Disparity among the three scores for individual cases was associated with the presence of comorbidities. The high correlations and correspondence among these scales demonstrate their reliability, validity, and utility in the assessment of dementia severity. The use of an average of these measures, with their increased precision, may give a more accurate indication of dementia severity over a broader range of impairment.

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30

Kereszturi, Monika, Jonathan Tawn, and Philip Jonathan. "Assessing extremal dependence of North Sea storm severity." Ocean Engineering 118 (May 2016): 242–59. http://dx.doi.org/10.1016/j.oceaneng.2016.04.013.

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31

Hassan, Z., J. K. Wong, J. Bush, A. Bayat, and K. W. Dunn. "Assessing the severity of inhalation injuries in adults." Burns 36, no. 2 (March 2010): 212–16. http://dx.doi.org/10.1016/j.burns.2009.06.205.

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32

Teres, D., and P. Pekow. "Assessing data elements in a severity scoring system." Intensive Care Medicine 26, no. 3 (March 2000): 263–64. http://dx.doi.org/10.1007/s001340051147.

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33

Paulin, Sven. "Assessing the Severity of Coronary Lesions with Angiography." New England Journal of Medicine 316, no. 22 (May 28, 1987): 1405–7. http://dx.doi.org/10.1056/nejm198705283162209.

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34

Chowdavaram, Suman, Prabhakar Boddu, K. Panduranga Rao, and B. Ramesh Kumar. "Lipid Profile in Assessing the Severity of Cirrhosis." Journal of Clinical and Experimental Hepatology 4 (March 2014): S42. http://dx.doi.org/10.1016/j.jceh.2014.02.086.

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35

Schnog, John-John B., Leroy R. Lard, Robert A. Rojer, Fey P. L. Van der Dijs, Frits A. J. Muskiet, and Ashley J. Duits. "New concepts in assessing sickle cell disease severity." American Journal of Hematology 58, no. 1 (May 1998): 61–66. http://dx.doi.org/10.1002/(sici)1096-8652(199805)58:1<61::aid-ajh11>3.0.co;2-8.

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36

Clarizio, Harvey F. "Assessing severity in behavior disorders: Empirically based criteria." Psychology in the Schools 27, no. 1 (January 1990): 5–15. http://dx.doi.org/10.1002/1520-6807(199001)27:1<5::aid-pits2310270102>3.0.co;2-d.

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37

Desai, Karishma, Marc Philip Frey, and Jerry Tan. "The Utility of Assessing Neck Acne." Journal of Cutaneous Medicine and Surgery 21, no. 1 (October 4, 2016): 82–83. http://dx.doi.org/10.1177/1203475416673051.

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Background: Acne grading is an essential component in establishing treatment options, but little is known on how neck acne should be incorporated into grading scales. Objective: Our objective was to explore the prevalence of neck acne and determine if its own severity category on an acne global grading scale was warranted. Methods: Acne severity was assessed in 6 categories: face, chest, back, anterior upper (AUN), anterior lower neck (ALN), and posterior neck (PN). Results: The overall prevalence of neck acne was 49%. Of these, 44% had AUN acne, 18.5% had ALN acne, and 19.8% had PN acne. AUN and facial acne had a significant correlation ( r = 0.37, P < .05). No correlation was seen amongst other areas. Males presented with a significantly higher severity of AUN (mean [SD], 1.37 [1.09]) than females (mean [SD], 0.52 [0.91]), on average. Conclusions: While neck acne has proven to be common amongst those with acne on other areas of the body, facial acne can be used as a proxy for classification, as neck severity is usually milder.

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38

Bollen, Thomas L., Vikesh K. Singh, Rie Maurer, Kathryn Repas, Hendrik W. van Es, Peter A. Banks, and Koenraad J. Mortele. "Comparative Evaluation of the Modified CT Severity Index and CT Severity Index in Assessing Severity of Acute Pancreatitis." American Journal of Roentgenology 197, no. 2 (August 2011): 386–92. http://dx.doi.org/10.2214/ajr.09.4025.

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39

Saghafi, Omeed. "Comparative Evaluation of the Modified CT Severity Index and CT Severity Index in Assessing Severity of Acute Pancreatitis." Journal of Emergency Medicine 41, no. 5 (November 2011): 569. http://dx.doi.org/10.1016/j.jemermed.2011.09.022.

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40

Elnashar, Shaimaa R., Eman Mahmoud Fouda, Terez Boshra Kamel, Wessam Sherin Shokry, Ramy Mohamed Mahmoud Ahmed, and Heba Allah Ahmed Ali. "Diagnostic value of pleural C-reactive protein levels in assessing severity of pediatric parapneumonic effusions." Voprosy praktičeskoj pediatrii 17, no. 4 (2022): 38–47. http://dx.doi.org/10.20953/1817-7646-2022-4-38-47.

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The immediate determination of complicated parapneumonic effusion is featured by instant remedial advantages. Consequently, we attempted to evaluate whether C-reactive protein (CRP) in pleural fluid can ameliorate the identification of cases with parapneumonic effusions that eventually require intervention. Patients and methods. A case-control study enrolled 43 patients with parapneumonic effusions from the inpatient ward and emergency room of Ain Shams Pediatric University Hospital, Egypt. Twenty of those patients had complicated effusions (complicated parapneumonic pleural effusion, CPPE), and 23 had uncomplicated parapneumonic pleural effusions (UCPPE). The differentiation characteristics of pleural fluid biochemical parameters as well as pleural CRP were estimated. Pleural fluid parameters were applied to classify cases of CPPE or UCPPE. ROC analysis established CRP setting to distinguish between both groups. Results. Pleural CRP was significantly higher in CPPE and empyema (48.97 mg/L) than in UCPPE (7.75 mg/L). The optimal cut-off point between CPPE and UCPPE in relation to pleural CRP was found to be 12.26 mg/L with a sensitivity of 95.00%, specificity of 95.65%, and AUC of 94.8%. Conclusion. Pleural fluid CRP can indeed be a beneficial spare test in pleural effusions and contribute to the differential diagnosis of CPPE and UCPPE. Key words: parapneumonic effusion, empyema, pleural CRP, pediatrics

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41

Yelskyi, I. K., A. A. Vasylyev, and N. L. Smirnov. "THE EFFICIENCY OF PROGNOSTIC SCALES IN STRATIFICATION OF ACUTE PANCREATITIS. LITERATURE REVIEW." Surgical practice, no. 3 (December 4, 2020): 17–28. http://dx.doi.org/10.38181/2223-2427-2020-3-17-28.

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The work carried out by analyzes of the literature data on assessing the severity of acute pancreatitis and predicting its course and mortality. A comparison of traditional point scales for assessing the severity of AP was made.As a result of a comparative analysis, it was found that the most objective instrumental method for diagnosing acute pancreatitis and its complications was MSCT with the determination of the CT index of severity. Balthazar scale allows assessing the severity of the disease and forming a prognosis for the development of complications. However, computed or magnetic resonance imaging with intravenous contrast enhancement allows an accurate assessment of the severity of the disease not earlier than 72 hours and has some contraindications.Estimating and predictive systems Ranson, APACHE, Krasnorogov, Bozhenkov systems, Pugaeva and Achkasova, BISAP and HAPS allow identyfying the severity of the clinical course of acute pancreatitis, have a high sensitivity, but at the same time require significant time and resources for execution. Glasgow-Imrie, SAPS, MODS, and SOFA scales mainly calculate mortality and degree of multiple organ failure in critically ill patients; these severity assessment systems are not specific for patients with acute pancreatitis.The optimal scale for assessing the severity of AP should allow assessing the patient's condition and prognosis from the moment of admission to the outcome of the disease. The practicing surgeon will be interested in an affordable, inexpensive, easy-to-use system for determining the severity of acute pancreatitis. For surgeons, the time factor plays a key role in determining tactics, and, therefore, improves the prognosis of the disease.

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42

Fuller, Jordan S., and Michael A. Young. "Assessing impairment using a configural measure." Methodological Innovations 12, no. 3 (September 2019): 205979911989079. http://dx.doi.org/10.1177/2059799119890794.

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Assessing impairment in daily functioning is an important part of a mental health evaluation and of monitoring progress in treatment. The Seasonality Assessment Form includes five yes/no impairment items written to reflect the ways that patients intuitively describe their levels of impairment. However, the items are not mutually exclusive and are not summative so that impairment severity is represented by the configural pattern of responses. This article used configural and graphical methods to examine the nature of response patterns and how to use them to generate an impairment severity score.

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43

Reaz, Nahid, Mirza Md Asaduzzaman, Shahnaj Akter Jahan, and Shafeya Khanam. "Accuracy of Platelet Count in Assessing Severity of Preeclampsia." Ibrahim Cardiac Medical Journal 4, no. 2 (July 20, 2016): 21–25. http://dx.doi.org/10.3329/icmj.v4i2.52987.

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Background and Objectives: The present cross-sectional study was conducted to determine whether platelet count can predict the severity of preeclampsia (PE) with fair degree of accuracy. Methodology: The study was carried out at Department of Obstetrics & Gynaecology, Dhaka Medical College Hospital, Dhaka between January 2013 to December 2013 on admitted preeclamptic women. Preeclamptic women ranging between 20-35 years, gestational age between 28-40 weeks and systolic pressure 140 mmHg and/or diastolic pressure 90 mmHg with proteinuria were the study population. A total of 96 preeclamptic women meeting the enrollment criteria were included in the study. Of them 76 had severe preeclampsia and 22 had mild preeclampsia. Platelet count below 1,50000/mm3 of blood was considered low in this study. Result: Over one-quarter (27.1%) of the patients were < 20 years, 43.8% (20 - 30) years and 29.2% 30 years old with mean age of the patients being 24.9 years. Over three-quarters (77.1%) of the patients belonged to middle class and 22.9% to lower class. Majority (79.2%) of the women was at term pregnancy with ratio of primigravida and multigravida being roughly 2:3. Eight (8.3%) patients had past history of PET. Over one-third (37.5%) of the patients had systolic blood pressure 160 mmHg and 27.1% had diastolic blood pressure 110 mmHg. About 64% of the patients had anemia and 73% had severe proteinuria (albumin 3+). More than 20% of the severe preeclamptics had low (< 1,50,000 per cu-mm of blood) platelet count as opposed to 9.1% of the mild preeclamptic group. The risk of having low platelet count among severe preeclamptics was found to be more than 2-fold (95% CI = 0.5 -12.1) than their mild preeclamptic counterparts (p = 0.037). Conclusion: The study concluded that, platelet count tends to fall as severity of preeclampsia increases. However, platelet count alone cannot predict the severity of preeclampsia as majority of the severe preeclampsia bears platelet within normal range. Ibrahim Cardiac Med J 2014; 4(2): 21-25

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44

Meira e Cruz, M., E. Chen, Y. Zhou, D. Shu, C. Zhou, and M. Kryger. "Using Circul® for assessing obstructive sleep apnea severity." Sleep Medicine 100 (December 2022): S305—S306. http://dx.doi.org/10.1016/j.sleep.2022.05.825.

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45

Polushin, Yu S., I. V. Shlyk, E. G. Gavrilova, E. V. Parshin, and A. M. Ginzburg. "The Role of Ferritin in Assessing COVID-19 Severity." Messenger of ANESTHESIOLOGY AND RESUSCITATION 18, no. 4 (August 30, 2021): 20–28. http://dx.doi.org/10.21292/2078-5658-2021-18-4-20-28.

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Ferritin is one of the biomarkers requiring special attention; its blood level increases significantly especially in the severe course of COVID-19. Information on the effect of hyperferritinemia on the disease outcome is very contradictory as are the ideas about the causes of its development.The objective: to study the effect of hyperferritinemia on the disease outcome and analyse the possible causes of its development in severe COVID-19.Subjects and Methods. Data on 479 patients with severe course of coronavirus infection treated in intensive care units (ICU) were retrospectively analyzed. Of them, the proportion of patients with a favorable outcome (Group 1) was 51.0% (n = 241), and with an unfavorable outcome (Group 2) - 49.0% (n = 235). The following parameters were assessed: the levels of ferritin, C-reactive protein, fibrinogen, IL-6, IL-10, IL-18, procalcitonin, complement C5a, total, direct and indirect bilirubin, ALT, AST, and the blood level of lactate dehydrogenase (LDH). The changes of erythrocyte count and hemoglobin blood level were also monitored. In order to form a clear view of iron metabolism, free iron, transferrin, and myoglobin levels were assessed in several patients with high ferritin values (more than 1,500 pg/L).Results. In the unfavorable outcome, ferritin levels increase very significantly, reaching maximum by day 6 of patients' stay in ICU. The difference in the level of ferritin between the groups of survivors and deceased during this period is clear and significant (p = 0.0013). The association of ferritin values with the outcome is detected as early as day 1, but by day 4 it becomes highly significant (the cut-off point is 1,080 pg/l). No data have been obtained that would indicate the association of hyperferritinemia with impaired iron metabolism, the development of hepatic dysfunction, or cellular destruction. In contrast to survivors, those who died on day 6 had elevated IL-6 while C5a level remained unchanged. Conclusions. The rapid increase in ferritin blood levels to 1,000 pg/L or higher is an unfavorable prognostic sign indicating a high probability of a lethal outcome. When assessing genesis of hyperferritinemia in COVID-19, the crucial significance should be attributed to the cytokine storm rather than disorders of iron metabolism or hemotoxic effects of the virus. The persistent increase of ferritin level in blood during 4-6 days of stay in ICU should be considered as a reason to intensify anticytokine therapy.

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Oye, Robert K., and Paul E. Bellamy. "Assessing Illness Severity and Outcome in Critically III Patients." Emergency Medicine Clinics of North America 4, no. 4 (November 1986): 623–33. http://dx.doi.org/10.1016/s0733-8627(20)31032-4.

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Shin, Yung Woo. "Indices for Assessing the Dynamic Severity of Mitral Stenosis." Korean Circulation Journal 21, no. 2 (1991): 287. http://dx.doi.org/10.4070/kcj.1991.21.2.287.

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Levy, Yair, Michelle M. Ramim, and Raymond A. Hackney. "Assessing Ethical Severity of e-Learning Systems Security Attacks." Journal of Computer Information Systems 53, no. 3 (March 2013): 75–84. http://dx.doi.org/10.1080/08874417.2013.11645634.

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Basketter, David A., John P. McFadden, and Ian Kimber. "Assessing the severity of allergic reactions: a regulatory dilemma." Contact Dermatitis 67, no. 1 (June 9, 2012): 3–8. http://dx.doi.org/10.1111/j.1600-0536.2012.02102.x.

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Xu, Yong-Hong, Ling Yan, Cheng Bian, Zi-Bin Tian, and Xue Jing. "Value of procalcitonin in assessing severity of acute pancreatitis." World Chinese Journal of Digestology 23, no. 30 (2015): 4898. http://dx.doi.org/10.11569/wcjd.v23.i30.4898.

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