Academic literature on the topic 'Asphyxia neonatorum'
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Journal articles on the topic "Asphyxia neonatorum"
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Ahmed, Iqbal, Umair Arshad, Fawwad Saleem, Hafiz Muhammad Anwar ul Haq, Sobia Tabassum, Arshia Sabir, and Hafiz Muhammad Ejaz ul Haq. "ASPHYXIA NEONATORUM." Professional Medical Journal 25, no. 08 (August 9, 2018): 1187–90. http://dx.doi.org/10.29309/tpmj/18.4617.
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Ahmed, Iqbal, Umair Arshad, Fawwad Saleem, Hafiz Muhammad Anwar Ul Haq, Sobia Tabassum, Arshia Sabir, and Hafiz Muhammad Ejaz Ul Haq. "ASPHYXIA NEONATORUM;." Professional Medical Journal 25, no. 08 (August 4, 2018): 1187–90. http://dx.doi.org/10.29309/tpmj/2018.25.08.61.
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Introduction: Severe hypoxic ischemic organ damage is caused by asphyxia innewborns which can follow fatal outcomes or severe life-long pathologies like renal insufficiency.We wanted to note the frequency of renal derangement in neonates having asphyxia neonatoumin this study. Setting & Period: Department of Pediatrics, Bahawal Victoria Hospital (BVH),Bahawalpur, from 1st January 2017 to 31st June 2017. Materials & Methods: Two hundredand sixty four neonates of both genders with birth asphyxia were included in the study. Mainoutcome was renal derangement in asphyxia neonatorum. Results: Mean weight was 2.54kg with standard deviation 0.50 kg and having mean APGAR score 4.43 with SD 1.66. 0It wasnoted that 189 (71.6%) neonates had Renal derangement in which 109 (57.7%) were males and80 (42.3%) were females with mean of weight was 2.53kg, having mean APGAR score 4.44.Conclusion: Renal derangement is quite common in neonates with birth asphyxia.
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Muthmainnah, Muthmainnah. "ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI TERJADINYA ASPHYXIA NEONATORUM PADA KEHAMILAN ATERM DI RSUD." Healthy-Mu Journal 1, no. 1 (July 31, 2017): 15. http://dx.doi.org/10.35747/hmj.v1i1.64.
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Asphyxia Neonatorum merupakan suatu keadaan dimana bayi baru lahir gagal bernafas spontan dan teratur segera setelah lahir. Asphyxia Neonatorum penyebab kematian dini pada Neonatus. Salah satu penyebab utama kematian bayi yang baru lahir adalah asphyxia bayi baru lahir. Menganalisa faktor yang mempengaruhi terjadinya asphyxia neonatorum pada kehamilan aterm di RSUD Ulin Banjarmasin. Metode penelitian ini adalah survey analitik, dengan pendekatan cross sectional variabel bebasnya adalah Asphyxia Neonatorum dan Variabel terikatnya adalah faktor yang mempengaruhi. Instrumen penelitian adalah check list dengan uji analisis menggunakan regresi logistik ganda. Faktor berat badan lahir janin mempengaruhi Asphyxia Neonatorum pada kehamilan aterm di RSUD Ulin Banjarmasin. Hasil uji statistik menunjukkan bahwa nilai exp B (OR) Faktor BBL Janin 5,873 artinya bahwa faktor BBL janin mempunyai pengaruh 5,873 kali lebih besar pada kejadian asphyxia neonatorum meningkatkan lagi penyuluhan tentang ANC sehingga dapat meminimalkan kejadian asphyxia neonatorum karena pengaruh BBL rendah janin.
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Muthmainnah, Muthmainnah. "Analisis Faktor-Faktor Yang Mempengaruhi Terjadinya Asphyxia Neonatorum Pada Kehamilan Aterm Di RSUD." Healthy-Mu Journal 1, no. 1 (August 30, 2017): 15–20. http://dx.doi.org/10.35747/hmj.v1i1.911.
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Asphyxia Neonatorum merupakan suatu keadaan dimana bayi baru lahir gagal bernafas spontan dan teratur segera setelah lahir. Asphyxia Neonatorum penyebab kematian dini pada Neonatus. Salah satu penyebab utama kematian bayi yang baru lahir adalah asphyxia bayi baru lahir. Menganalisa faktor yang mempengaruhi terjadinya asphyxia neonatorum pada kehamilan aterm di RSUD Ulin Banjarmasin. Metode penelitian ini adalah survey analitik, dengan pendekatan cross sectional variabel bebasnya adalah Asphyxia Neonatorum dan Variabel terikatnya adalah faktor yang mempengaruhi. Instrumen penelitian adalah check list dengan uji analisis menggunakan regresi logistik ganda. Faktor berat badan lahir janin mempengaruhi Asphyxia Neonatorum pada kehamilan aterm di RSUD Ulin Banjarmasin. Hasil uji statistik menunjukkan bahwa nilai exp B (OR) Faktor BBL Janin 5,873 artinya bahwa faktor BBL janin mempunyai pengaruh 5,873 kali lebih besar pada kejadian asphyxia neonatorum meningkatkan lagi penyuluhan tentang ANC sehingga dapat meminimalkan kejadian asphyxia neonatorum karena pengaruh BBL rendah janin.
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Astutik, Reni Yuli, and Nency Ferawati. "Hubungan Bayi Berat Lahir Rendah dengan Kejadian Asfiksia Neonatorum di RSUD Dr. Iskak Tulungagung." Jurnal Kebidanan Midwiferia 4, no. 1 (January 18, 2019): 1. http://dx.doi.org/10.21070/mid.v4i1.1845.
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Birth weight is one factor of neonates that can cause asphyxia neonatorum and is one indicator ofthe health of the newborn. The result of Riskesdas 2013 explained the low birth weight infants is 10.2% and WHO data shows every year about 3% of 120 million newborn have asphyxia. This study aims to analyze the correlation of low birth weight infants with neonatorum asphyxia incidence in dr. Iskak Tulungagung Hospital year 2016. This study was executed on July 18 to 19 2017 in dr.Iskak Tulungagung Hospital. The type research used analytical survey with correlational design and retrospective cohort study. Independent variable was low birth weight infants and dependent variable was neonatorum asphyxia. The population was 949 and sample was 162 with Simple Random Sampling technique, and used medical record instruments. From the 162 samples, found that almost half of respondents were 46.9% experienced low birth weight infants and almost all of the respondents were 88.3% experienced asphyxia neonatorum. Based on chi square test obtained (p)=0.001<(α)=0,05 and C=0,257, it means there is significant correlation between low birth weight infants and asphyxia with low correlation neonatorum. Odds ratio is 9,116, it means that risk of asphyxia neonatorum at low birth weight infants is 9.116 times great than normal birth weight infant. At the low birth weight infants a lot of risk of problems in the body because immaturity of organ system, so easily attacked by complications such as an asphyxia neonatorum.
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Syalfina, Agustin Dwi, and Shrimarti Rukmini Devy. "Analysis Risk Factors of Asphyxia Neonatorum." Jurnal Berkala Epidemiologi 3, no. 3 (September 1, 2015): 265. http://dx.doi.org/10.20473/jbe.v3i3.2015.265-276.
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ABSTRACTAntenatal care is designed to promote, protect, and maintain the health during pregnancy and reduce maternal and neonatal mortality. The scope of antenatal care also includes the detection and special care for high risk cases as well as the prediction and prevention of complications during pregnancy and childbirth. Complications of pregnancy and childbirth causes of neonatorum asphyxia. Neonatorum asphyxia is a condition where the baby can not breathe spontaneously and regularly after birth. Neonatorum asphyxia cases in Mojokerto district has 46.9% in 2010 and 39.7% in 2014. This aim of this study was to analyze the effect of the quality of antenatal care to neonatorum asphyxia in Mojokerto. The type of this study was observational analytic with case control design with a sample of cases and controls amounted to 80 babies. Data was analyzed using univariate, bivariate and multivariate analysis with logistic regression. The results of this study showed that the quality of antenatal care was significant with neonatorum asphyxia (OR = 8,556; 95% CI:2,777–26,358). Confounding variables associated with neonatorum asphyxia were maternal occupation (OR = 4,558;95% CI:1,391– 14,298), primary education (OR = 21,620; 95% CI: 1,932–241,886), secondary education (OR = 20,977; 95%CI: 1,819–241,872). The conclusion quality of antenatal care has effect of nenatorum asphyxia. Suggestions can be drawn based on the results of this study are for health workers are expected to do health education to the public and families about the importance of antenatal care and antenatal care services that should be obtained from health workers.Keywords: quality of antenatal care, neonatorum asphyxia, case control
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Syalfina, Agustin Dwi, and Shrimarti Rukmini Devy. "Analysis Risk Factors of Asphyxia Neonatorum." Jurnal Berkala Epidemiologi 3, no. 3 (September 1, 2015): 265. http://dx.doi.org/10.20473/jbe.v3i32015.265-276.
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Antenatal care is designed to promote, protect, and maintain the health during pregnancy and reduce maternal and neonatal mortality. The scope of antenatal care also includes the detection and special care for high risk cases as well as the prediction and prevention of complications during pregnancy and childbirth. Complications of pregnancy and childbirth causes of neonatorum asphyxia. Neonatorum asphyxia is a condition where the baby can not breathe spontaneously and regularly after birth. Neonatorum asphyxia cases in Mojokerto district has 46.9% in 2010 and 39.7% in 2014. This aim of this study was to analyze the effect of the quality of antenatal care to neonatorum asphyxia in Mojokerto. The type of this study was observational analytic with case control design with a sample of cases and controls amounted to 80 babies. Data was analyzed using univariate, bivariate and multivariate analysis with logistic regression. The results of this study showed that the quality of antenatal care was significant with neonatorum asphyxia (OR = 8,556; 95% CI:2,777–26,358). Confounding variables associated with neonatorum asphyxia were maternal occupation (OR = 4,558;95% CI:1,391– 14,298), primary education (OR = 21,620; 95% CI: 1,932–241,886), secondary education (OR = 20,977; 95%CI: 1,819–241,872). The conclusion quality of antenatal care has effect of nenatorum asphyxia. Suggestions can be drawn based on the results of this study are for health workers are expected to do health education to the public and families about the importance of antenatal care and antenatal care services that should be obtained from health workers.Keywords: quality of antenatal care, neonatorum asphyxia, case control
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Hardiana, Hardiana. "HUBUNGAN PARTUS LAMA DAN KETUBAN PECAH DINI DENGAN KEJADIAN ASFIKSIA NEONATORUM DI RSUD RADEN MATTAHER JAMBI." MIDWIFERY HEALTH JOURNAL 4, no. 2 (December 15, 2019): 1. http://dx.doi.org/10.52524/jurnalkebidananjambi.v4i2.16.
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One cause of infant mortality is asphyxia, asphyxia is a condition where the baby immediately after birth does not breathe spontaneously and regularly. Based on data from Raden Mattaher General Hospital in Jambi Province in 2017 there were 107 cases of asphyxia and in 2018 the number of data on asphyxia patients increased to 116 cases.
This study aims to determine the relationship of the old and amniotic early rupture with neonatorum asphyxiation in Raden Mattaher General Hospital Jambi Province in 2018.
The study used a case control research method with a population of 116 respondents and control 116 respondents using random sampling technique. So the number of samples is 232 respondents. Data collection was done by filling out the checklist sheet carried out on March 27 with univariate and bivariate analysis.
The results showed that the Old Partus group who experienced no Asphyxia were 42 infants (39.3%) and the Old Partus who had 65 Asphyxia (60.7%). This means that there is a relationship between the Old Partus and the Neonatorum Asphyxia with a p-value of 0.004 and OR 2.246. and those who did not experience premature rupture of amniotic neonatorum 65 infants (43.6%), and early rupture of membranes who experienced neonatorum asphyxia (38.6%). And there is a relationship between Early Ruptured Amniotic and Asphyxia Neonatorum with p-value 0.014 and OR 0.486. So there is a relationship between the Old Partus and the Amniotic Early Rupture with the occurrence of Neonatorum Asphyxia in Raden Mattaher General Hospital Jambi.
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Maringga, Estin Gita, and Nunik Ike Yuniasari. "Hubungan Usia Gestasi terhadap Kejadian Asfiksia Neonatorum di RSUD Kabupaten Kediri Periode Januari s/d Juni 2017." Jurnal Kebidanan Midwiferia 3, no. 2 (October 3, 2017): 29. http://dx.doi.org/10.21070/mid.v3i2.1576.
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Infant mortality now needs more attention from various parties, especially infant mortality caused by asphyxia neonatorum. Based on WHO data, the number of newborn deaths as many as 4 million babies as a result of asphyxia neonatorum, this condition contributes to the death rate in children under 5 years old of 38%. This study aims to determine the correlation of gestational age to the incidence of asphyxia neonatorum in Kediri Regency Hospital Period of January to June 2017. This study is an analytic study with retrospective cohort approach. This study took place in Kediri Regency Hospital. The study data were taken on 2-28 November 2017. The sample size was 62 respondents, chosen by simple random sampling technique. The independent variable is gestational age and the dependent variable is the level of asphyxia neonatorum. Dependent and independent variables were measured using data collection sheets, the data were taken from the medical record. Quantitative data analysis techniques used spearman rank test. 35 respondents who had aterm gestational age, 60% of them had moderate asphyxia, while from 24 respondents who had preterm gestational age, 83.3% of them had moderate asphyxia and 12.5% had severe asphyxia. The analysis result of Spearman Rank of IBM SPSS was 22 asymp sign (2 tailed) obtained result as α= 0.01 < 0.05. Gestational age has a significant correlation with the incidence of asphyxia neonatorum
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Masruroh, Nely, Yonas Hadisubroto, and Rena Normasari. "The Difference of Asphyxia Neonatorum Incident between Very Preterm Labor That Is Followed or Not by Premature Rupture of Membranes at RSD dr. Soebandi of Jember." Journal of Agromedicine and Medical Sciences 4, no. 3 (October 11, 2018): 147. http://dx.doi.org/10.19184/ams.v4i3.6394.
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Asphyxia neonatorum is an infant's inability to breathe spontaneously and regularly soon after birth. Risk factors of neonatal asphyxia are preterm labor and premature rupture of membranes. In the poor and developing countries there are many occurrences of asphyxia at gestation less than 32 weeks (very preterm). The aim of this study is to describe the incidence of asphyxia neonatorum in very preterm labor followed by premature rupture of membranes, describes the incidence of asphyxia neonatorum in very preterm labor that is not followed by premature rupture of membranes, and the difference of asphyxia neonatorum incident between very preterm labor that is followed or not by premature rupture of membranes. The type of this research was retrospective analytical observational with cross sectional approach and total sampling technique. The population was a single preterm delivery mother with spontaneous presentation of heads born in RSD dr. Soebandi from January 2015 - January 2017. From 465 mothers, 65 mothers meet the inclusion criteria. Data is processed and presented in the form of frequency distribution table then analyzed using Chi-Square test. The results showed that mothers with very preterm followed by premature rupture of membranes did not have asphyxia (22 mothers or 33.8%) and mothers with very preterm that is not followed by premature rupture of membranes did not have asphyxia (18 mothers or 27.2%). Based on Chi-Square statistical test results obtained p-value (0.298)> α (0.05) and it can be concluded that is statistically at 95% confidence level there is no significant difference in the incident of asphyxia neonatorum between very preterm labor that is followed or not by premature rupture of membranes in RSD dr. Soebandi Kabupaten Jember.Keywords: Asphyxia neonatorum, preterm labor, premature rupture of membranes
Dissertations / Theses on the topic "Asphyxia neonatorum"
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Power, David John Donovan. "Asphyxia neonatorum in a developing world situation : a study of the impact of asphyxia neonatorum in term infants on the pattern of handicap in the Ciskei; an evalution of its epidemiology and a trial of the efficacy of current therapy." Doctoral thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/27190.
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This study addresses the problem of asphyxia neonatorum in a developing African community in the Mdantsane region of Ciskei. It also documents asphyxia as a prominent cause of childhood handicap, examines aspects of its epidemiology and evaluates the effectiveness of a regimen of phenobarbitone and dexamethasone in limiting subsequent neurological deficit in asphyxiated neonates. Analysis of neonatal deaths at Cecilia Makiwane Hospital over an 18-month period showed that asphyxia accounted for one third of all neonatal deaths. In particular, asphyxia caused two thirds of deaths in infants over 2 Kg birth weight. From a hospital register of handicapped children, 211 had cerebral palsy. Asphyxia was the cause of cerebral palsy in 33% of these children. Spastic quadriplegia, the type of cerebral palsy most often resulting from the cerebral damage associated with asphyxial hypoxic-ischaemic insults, was by far the largest diagnostic category (57%). Asphyxia therefore appears to be the single largest cause of significant handicap in Ciskei. In view of the underdeveloped support services to parents in most developing areas, the problem of asphyxia is of considerable importance. In the study of the epidemiology of asphyxia, details of pregnancy and labour were obtained for 163 asphyxiated term infants and 2758 non- asphyxiated term infants whose mothers had delivered in the hospital. The factors positively associated with asphyxia were: low gravidity and parity, failure to book for antenatal care, the occurrence of antenatal disorders, the occurrence of fetal distress, a prolonged first stage of labour and delivery by caesarean section or vacuum extraction. Maternal age and the actual number of antenatal visits were not associated with asphyxia. The causes of asphyxia assigned by the specialist obstetrician in charge were cephalopelvic disproportion (CPD) (39%), utero-placental pathologies (22%), other (8%), and "unknown" where he could find no abnormality in pregnancy and labour (27%). From these findings it appears that the steps that need to be taken for prevention include: active recruitment of patients to book for antenatal care, more active detection and management of cephalopelvic disproportion and basic research to elucidate the causes of the "unknown" group whom it is speculated have undetected utero-placental pathology.
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Yudkin, Patricia L. N. "Consequences of birth asphyxia." Thesis, University of Oxford, 1993. http://ora.ox.ac.uk/objects/uuid:d1bc3e23-8a51-4c7b-a0cd-e76f7b5aaa89.
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To investigate the relationship between birth asphyxia and neurological impairment a cohort of 184 infants with a low (≤3) one-minute Apgar score was studied. All were singletons, apparently normally formed, and born at term (≥37 weeks' gestation) in the John Radcliffe Hospital, between January 1984 and September 1985. The 181 cohort survivors were traced at the age of five years; 159 were assessed by a paediatrician on a battery of neurodevelopmental tests, and information about a further eight was obtained from other sources. Three infants in the cohort died neonatally with a diagnosis of birth asphyxia, and three had spastic quadriplegia, profound developmental delay and visual impairment. Examination of the perinatal histories of these six children, including their fetal heart rate patterns in labour and acid-base status at delivery, found convincing evidence of birth asphyxia. Only one other child in the cohort exhibited similar signs of birth asphyxia; he was unimpaired at the age of five. To assess the impact of birth asphyxia on the overall rate of cerebral palsy, all cases of cerebral palsy born to Oxford residents in the study period were identified. Of 30 cases of cerebral palsy, the three identified in the follow-up study were the only ones whose impairment could be attributed to birth asphyxia in a full-term birth. Birth asphyxia therefore accounted for 10% of all cases of cerebral palsy, a fraction that agrees with previous estimates. The frequency of cerebral palsy due to birth asphyxia was estimated as 1 in 3800 full-term livebirths. A detailed analysis of the test scores of the 159 children assessed by the paediatrician failed to show any association between their acid-base values at delivery and test scores, or between their fetal heart rate patterns in labour and test scores. These results conform with the view that birth asphyxia has an "all or nothing" effect, and that it presents as a cluster of abnormal neonatal signs, including persistent cerebral depression, severe acidaemia, neonatal encephalopathy, and multiorgan dysfunction.
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Andersen, Danielle Louise. "Development of neurotransmitter receptors in the human brain and vulnerability to perinatal asphyxia and sudden infant death syndrome /." St. Lucia, Qld, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17412.pdf.
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Pennell, Craig Edward. "The role of lactate measurement in the prediction of fetal hypoxic-ischaemic brain injury during labour." University of Western Australia. School of Women's and Infants' Health, 2004. http://theses.library.uwa.edu.au/adt-WU2003.0037.
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[Truncated abstract] In this thesis the role of lactate measurement has been evaluated in intrapartum assessment of fetal wellbeing. Specifically, I have addressed the question of whether fetal lactate measurement is better than the assessment of fetal heart rate patterns or the measurement of pH at predicting fetal brain injury after intrapartum asphyxia. Using an ovine model of repeated umbilical cord occlusion designed to mimic events which may occur during human labour, I have shown that the measurement of fetal lactate levels after repeated cord occlusion is significantly associated with the severity of brain injury after the asphyxial insult. No significant associations were identified with fetal pH measurements or with the duration of decelerative or compound fetal heart rate patterns; however, this is the first study to describe an association between the duration of both increased fetal heart rate variability and fetal heart rate overshoot with the severity of subsequent brain injury. Although no significant association was identified between fetal arterial pressure measured between umbilical cord occlusions and the grade of brain injury, the studies performed in this thesis are the first to show a strong correlation between the duration of specific arterial pressure responses during cord occlusions and the grade of brain injury, accounting for approximately 90% of the variability seen in the severity of injury. The mechanism responsible for the improved ability of lactate measurement to predict fetal brain injury is unknown. It may be because fetal lactate levels are a more stable marker of anaerobic metabolism of glucose than fetal pH levels, which are influenced by both increasing levels of carbon dioxide and anaerobic metabolism of amino-acids and fatty acids. In addition fetal pH levels can be rapidly normalised through placental exchange of carbon dioxide whereas fetal lactate levels are slow to normalise across the placenta as they rely on facilitated diffusion.
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Alsina, Casanova Miguel M. "Disfunción multiorgánica en el recién nacido con Encefalopatía hipóxico-isquémica en la era de la Hipotermia terapéutica." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/664113.
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La aproximación al paciente asfíctico desde el punto de vista neurológico es fundamental por las implicaciones a corto y largo plazo, sin embargo el insulto hipóxico-isquémico altera la homeostasis global del recién nacido afectando a los diferentes órganos y sistemas. La evidencia científica acerca del daño extraneural en el recién nacido asfíctico hasta el momento actual es escasa y los estudios pertenecen a la era previa a la implantación de la hipotermia terapéutica que ha supuesto un cambio de paradigma clínico en este tipo de pacientes. Por otra parte, dado que la mayor parte de recién nacidos con encefalopatía hipóxico-isquémica nacen en centros que no disponen de hipotermia terapéutica, estos pacientes necesitarán ser trasladados en hipotermia pasiva a centros de referencia. El transporte de estos pacientes supone un reto, principalmente por la necesidad de mantener la temperatura en el rango de seguridad.
Esta tesis, en base al estudio de una serie amplia de pacientes con el espectro completo de encefalopatía hipóxico-isquémica, ha abordado aspectos determinantes y hasta el momento desconocidos en el manejo del recién nacido asfíctico como son, en primer lugar, la correlación del daño multiorgánico y la encefalopatía hipóxico-isquémica en la era de la hipotermia terapéutica, aportando datos de gran utilidad clínica. Podemos concluir que la disfunción de otros órganos es prácticamente universal en el paciente con cualquier grado de encefalopatía hipóxico-isquémica en la era de la hipotermia terapéutica. El daño extraneural se correlaciona con la gravedad de la encefalopatía hipóxico-isquémica, sin embargo esta correlación se funda básicamente en la diferencia en el grado de afectación multiorgánica entre los pacientes con encefalopatía grave y los pacientes con encefalopatía moderada y leve. De esta manera, podemos establecer los siguientes patrones de afectación sistémica según el grado de EHI: 1) En el paciente con encefalopatía grave se debe anticipar una disfunción moderada o grave de otros órganos desde las primeras 24 horas de vida. En caso de no producirse, es preciso descartar exhaustivamente otras causas de encefalopatía neonatal. 2) Los pacientes con encefalopatía moderada con frecuencia presentan afectación orgánica de escasa relevancia clínica, pero una minoría de casos puede presentar
afectación sistémica moderada o grave. 3) Los pacientes con encefalopatía leve presentan habitualmente afectación sistémica leve y resuelven con rapidez las alteraciones en la homeostasis. Respecto al perfil de afectación orgánica, el hígado y el medio interno son los órganos o sistemas que se afectan con mayor frecuencia en el recién nacido con encefalopatía hipóxico-isquémica, sin embargo los órganos afectados con mayor gravedad son el sistema respiratorio y cardiovascular. La disfunción renal y hematológica se producen con menor frecuencia que el resto de órganos o sistemas, sin embargo en el caso del daño renal, su afectación es con frecuencia clínicamente relevante. Así mismo, el daño extraneural en el paciente con encefalopatía hipóxico-isquémica es más intenso en las primeras 24 horas de vida. Los pacientes que sobreviven presentan una tendencia a mejorar a lo largo de las primeras 72 horas de vida.
En segundo lugar, el estudio del curso del transporte del recién nacido con encefalopatía hipóxico isquémica nos ha permitido dilucidar como la gravedad de la encefalopatía hipóxico-isquémica se correlaciona inversamente con la temperatura durante el transporte en hipotermia pasiva. Los pacientes con encefalopatía grave presentan un mayor riesgo de sobreenfriamiento durante el transporte en hipotermia pasiva. Por otra parte, los eventos adversos más frecuentemente descritos durante el transporte interhospitalario en hipotermia pasiva son el deterioro cardiovascular, la presencia de hipoglucemia y sangrado endotraqueal, estos podrían disminuir con una mejor estabilización previa al transporte y con un mejor control de la temperatura.Perinatal asphyxia is a major cause of multiorgan dysfunction in the newborn. Only scarce data about the correlation of extracerebral damage and the severity of hypoxic-ischemic encephalopathy are available. This information might help to anticipate the evolution of multiorgan dysfunction according to the severity of hypoxic-ischemic encephalopathy and vice versa. On the other hand, hypoxic-ischemic encephalopathy has become a time- dependent emergency after clinical trials demonstrated the efficacy of cooling started within 6 hours of birth in reducing the risk of death or disability. Most asphyxiated infants are born in non-tertiary neonatal units and they must be transferred urgently to a center equipped with a hypothermia program. To start hypothermia as soon as possible, transferred infants are passively cooled. Nevertheless, studies do not outline medical complications during transport nor indicate whether the efficacy in maintaining target temperatures and complications are related to the severity of the hypoxic-ischemic encephalopathy in the first 6 h of life. This is the first study to evaluate the correlation of multiple organ dysfunction with the severity of hypoxic-ischemic encephalopathy. In the hypothermia era, multiple organ damage continues to be almost universal in newborns with hypoxic-ischemic encephalopathy. There is a high correlation between the severity of hypoxic-ischemic encephalopathy and multiple organ injury during the first 3 days of life. Therefore, a high index of suspicion of relevant multiorgan dysfunction is required in infants admitted with a diagnosis of severe hypoxic-ischemic encephalopathy. Patients with moderate hypoxic-ischemic encephalopathy present wide variability in the severity of multiorgan dysfunction. Finally, in the absence of multiorgan dysfunction a perinatal hypoxic-ischemic origin of acute severe neonatal encephalopathy should be carefully reconsidered. Secondly, this study shows that the risk of overcooling during transport is greater in newborns with severe hypoxic- ischemic encephalopathy and those with more severe acidosis at birth. The most common adverse events during transport are related to physiological deterioration and bleeding from the endotracheal tube. This observation provides useful information to identify those asphyxiated infants who require closer clinical surveillance during transport.
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Barbosa, Naila de Oliveira Elias. "Influência do crescimento intra-uterino restrito e da asfixia perinatal sobre os níveis séricos de magnésio em recém-nascidos de termo na primeira semana de vida." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-19092014-112942/.
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O Magnésio é o segundo cátion intracelular mais comum e desempenha importante papel na modulação de funções de transporte e receptores, atividades enzimáticas, metabolismo energético, síntese de proteínas e ácidos nucleicos e proteção de membranas biológicas. Apesar de sua importância, o conhecimento de sua homeostase não é completo, principalmente por dificuldade de acesso a seus estoques intracelulares e da ausência de métodos laboratoriais confiáveis para medida da fração iônica. O desenvolvimento recente de um eletrodo íon-seletivo permitiu a determinação das concentrações de Mg iônico(Mgi), em pequenas amostras de sangue, o que possibilitou a realização de estudos para determinação desta fração no período neonatal. A presença de alguns distúrbios, como o Crescimento Intra-uterino Restrito(CIUR) e a Asfixia Perinatal, poderiam potencialmente levar a desvios da homeostase do Mg, ainda não totalmente esclarecidos. O objetivo deste estudo foi descrever, em Recém-nascidos de termo(RNT) sem CIUR, os níveis de Mgi e total (MgT) em sangue de cordão umbilical, 3o e 7o dias de vida e comparar os valores obtidos entre os RNT, com e sem CIUR e asfixia perinatal. Realizou-se um estudo prospectivo, no qual foram incluídos 95 RNT, divididos em dois grupos de estudo: Grupo I - sem CIUR(50 RN - 52,6%) e Grupo II - com CIUR(45 RN - 47,4%). A presença de CIUR foi determinada por um peso de nascimento abaixo do percentil 10 para a curva de Ramos(1983), associado a uma relação P/P50 < 0,85. Cada um desses grupos foi subdividido em 2 subgrupos : Grupo Ia - 30 RN (31,6%), sem CIUR e sem asfixia perinatal; Grupo Ib - 20 RN(21,0%), sem CIUR e com asfixia perinatal; Grupo IIa - 40 RN(42,1%), com CIUR e sem asfixia perinatal; Grupo IIb - 5 RN(5,3%), com CIUR e asfixia perinatal. A presença de asfixia perinatal foi indicada por um Apgar de 5o minuto < 6 associada a presença de um dos seguintes critérios: pH de sangue de cordão umbilical < 7,2 , disfunção de um ou mais órgãos, sequelas neurológicas no período neonatal imediato. Foram realizadas determinações de Mgi, Cálcio iônico(Cai), Uréia(U), pH, MgT, Fósforo(P) e Creatinina(Cr), em sangue de cordão umbilical, no 3o e no 7o dias de vida. Verificou-se que nos RNT sem CIUR(Grupo Ia), as concentrações médias de MgT, ao nascimento, foram menores do que as de RN com CIUR e elevaram-se, de forma significante, até o 7o dia de vida, enquanto as de Mgi mantiveram-se. As concentrações de Mgi neste grupo, foram significativamente menores do que as de RN com CIUR(Grupo IIa) durante a 1a semana de vida e do que as de RN com asfixia perinatal(Grupo Ib) no 3o e 7o dias de vida. Concluiu-se que, em RNT sem CIUR, há um aumento dos níveis de MgT durante a 1a semana de vida, sem alteração das concentrações de Mgi. A presença de CIUR, bem como a asfixia perinatal, podem influenciar as concentrações neonatais de Mg, através de seus efeitos de modulação da homeostase deste íon, durante os períodos fetal e neonatalMagnesium is the second most abundant intracellular cation and plays an important role in regulation of transporting and receptors functions, enzymatic activities, energy metabolism, protein and nucleic acid synthesis and biologic membranes protection. In spite of this, the knowledge of its homeostasis is still limited, mainly due to inacessibility of its intracellular stores and the absence of a reliable methodology to measuring the ionized fraction. The recent development of an ion-selective electrode has allowed not only the determination of ionized magnesium(iMg) concentrations in a small blood sample volume, but also an increasing number of researches as to this fraction in neonatal period. The presence of some disorders,i.e. like Intrauterine Growth Restriction (IUGR) and Perinatal Asphyxia, could lead to an unclear imbalance of magnesium homeostasis, in a way not yet clear. The aim of this study was to describe, in term newborns without IUGR, iMg and Total Mg (TMg) concentrations in umbilical cord blood, third and seventh days of life and to compare the results among term newborns with and without IUGR and perinatal asphyxia. Ninety-five term newborn infants were enrolled in a prospective study and were divided into two study groups: Group I : without IUGR(50RN - 52.6%) and Group II - with IUGR(45RN - 47.4%). Intrauterine growth restriction was defined as a birth weight below the 10th percentil for Ramos Curve(1983) besides to a birth weight ratio <0,85. Each one of these groups were divided in two subgroups: Group Ia :30 RN (31,6%), without IUGR or perinatal asphyxia; Group Ib : 20 RN (21,0%), without IUGR, with perinatal asphyxia ; Group IIa : 40 RN (42,1%), with IUGR, without perinatal asphyxia; Group IIb: 5 RN(5,3%), with perinatal asphyxia and IUGR. Perinatal asphyxia was defined as a 5 minutes Apgar score < 6 besides to one of the following: umbilical cord blood pH < 7,2, disfunction of one or more organs, neonatal neurologic manifestations. iMg, TMg, ionized calcium, urea, pH, phosphorus and creatinine concentrations were determined in umbilical cord blood, third and seventh days of life. We observed that in term newborns without IUGR (Group Ia), TMg concentrations increased significantly during the first week of life, while iMg concentrations remained unchanged. iMg levels in this group, were significantly lower than in the group with IUGR (Group IIa) from birth to 7th day of life and than in the group without IUGR, with perinatal asphyxia (Group Ib) in the third and seventh days of life. We concluded that in term newborns without IUGR, TMg levels increased during the first week of life, while iMg levels remained unchanged. The presence of IUGR, as well as, perinatal asphyxia, may influence neonatal levels of magnesium, through their effect on the modulation of this ion homeostasis, during fetal and neonatal periods
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Genovesi, Fernanda Françoso. "Comparação entre os General Movements Assessment e Escala Motora Infantil de Alberta em recém-nascidos e lactentes de risco para alterações do desenvolvimento motor." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5170/tde-22092017-154531/.
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Introdução: O aperfeiçoamento da assistência pré-natal e neonatal contribuiu para maior sobrevida dos recém-nascidos com riscos para alterações do desenvolvimento. A detecção precoce e eficaz destes riscos é fundamental para a intervenção oportuna e minimização dos danos funcionais. A avaliação com melhor valor preditivo para anormalidades é pelos General Movements (GMs), porém a mais utilizada no Brasil é a Escala Motora Infantil de Alberta (EMIA). Objetivo: Verificar a validade dos GMs e da EMIA com um e três meses de idade para predizer o desfecho do desenvolvimento motor pela EMIA aos seis e 12 meses. Método: Estudo observacional longitudinal com 45 recém-nascidos e lactentes do Hospital Universitário da Universidade de São Paulo, avaliados do nascimento até os cinco meses de idade (corrigida, se prematuros) pelos GMs, e de um a 12 meses pela EMIA. Foi realizada análise descritiva e testes de kappa e curva roc para a comparação entre as avaliações. Resultados: Os participantes (masculino = 51,1%) apresentaram idade gestacional média de 34 semanas; 57,7% apresentaram alteração em pelo menos uma avaliação pelos GMs, com predomínio do repertório pobre (RP) e fidgety movements (FM) ausentes, enquanto 46,6% apresentaram alguma alteração na EMIA. A maioria (85,7%) apresentou avaliações normais aos 12 meses de idade pela EMIA; e os com avaliações anormais também tiveram GMs alterados em toda sua trajetória. Houve pobre confiabilidade entre os GMs e a EMIA no primeiro (kappa: 0,165) e no terceiro mês, ligeira confiabilidade (kappa: 0,259). Comparando os writhing movements (WM) com a EMIA com um mês, para prever desfecho aos seis meses de idade, foi encontrado uma sensibilidade dos WM de 78,6% e uma especificidade de 100%. Valores melhores de sensibilidade e especificidade também foram encontrados nos WM para desfecho com 12 meses de idade (sensibilidade de 75% e especificidade em 100%). Os lactentes que apresentavam alguma alteração nas avaliações eram encaminhados para fisioterapia. Conclusão: Foi possível observar um grande número de participantes com GMs alterados, porém com diminuição/normalização nas avaliações pela EMIA, podendo ser devido a intervenção fisioterapêutica nos casos mais graves. A avaliação com melhores valores para predição do desenvolvimento são os GMs na fase dos WMs. Não existe correlação entre a avaliação dos GMs com 1 mês e EMIA 1 com mês, nem entre estes dois métodos aos 3 mesesIntroduction: Improvement of prenatal and neonatal care has contributed to a greater survival of newborns with risks for developmental disorders. Early and effective detection of these risks is essential for timely intervention and minimization of functional impairment. The most predictive value for abnormalities is the General Movements (GMs), but the most used in Brazil is the Alberta Infant Motor Scale (AIMS). Objective: To verify the validity of GMs and EMIA at one and three months of age to predict the outcome of motor development by EMIA at six and 12 months. Method: A longitudinal observational study with 45 newborns and infants of the University Hospital of the University of São Paulo, evaluated from birth to five months of age (corrected, if premature) by GMs, and from one to 12 months by EMIA. Descriptive analysis and kappa and roc curve tests were performed to compare the evaluations. Results: Participants (male = 51.1%) had a mean gestational age of 34 weeks; 57.7% presented alterations in at least one evaluation by GMs, with a predominance of poor repertoire (RP) and fidgety movements (FM) absent, while 46.6% had some alteration in EMIA. The majority (85.7%) presented normal evaluations at 12 months of age by EMIA; And those with abnormal ratings also had altered GMs throughout their trajectory. There was poor reliability between GMs and EMIA in the first (kappa: 0.165) and in the third month, slight reliability (kappa: 0.259). Comparing writhing movements (WM) with EMIA at one month, to predict outcome at six months of age, a WM sensitivity of 78.6% and a specificity of 100% was found. Better sensitivity and specificity values were also found in WM for 12-month-old outcome (75% sensitivity and 100% specificity). Infants who presented some alterations in the assessments were referred to physical therapy. Conclusion: It was possible to observe a large number of participants with altered GMs, but with a decrease / normalization in the evaluations by EMIA, and may be due to physiotherapeutic intervention in the most severe cases. The best predictive values for development prediction are GMs in the WM phase. There is no correlation between the evaluation of GMs at 1 month and EMIA 1 with month, nor between these two methods at 3 months
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Nalla, Mohammed Sayed. "The contribution of intrapartum asphyxia to the development of cerebral palsy in full term infants: a systematic review." Thesis, 2014.
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Padayachee, Natasha. "outcomes of neonates with perinatal asphyxia at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH) from 2007-2011." Thesis, 2015. http://hdl.handle.net/10539/17341.
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A Research Report submitted to the Faculty of Science, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Master of Medicine in Paediatrics.
8 May 2014Background: Perinatal asphyxia is a significant cause of death and disability. Aim: To determine the outcomes (survival to discharge and morbidity post discharge) of neonates with perinatal asphyxia at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH). Methods: This was a descriptive retrospective study. Patient information was obtained from the computerised neonatal database of neonates admitted to CMJAH within 24 hours of birth between 1 January 2006 and 31 December 2011 with a birth weight of >1800 grams and a 5 minute Apgar score <6. Results: 450 babies were included in the study; 185 females (41.1%). Mean birth weight was 3034.80 grams (SD 484.936) and mean gestational age was 39.11 weeks (SD 2.2). Most babies were inborn 391/450 (86.9%) and most were delivered by normal vaginal delivery 270/450 (60%). The overall survival was 390/450 (86.6%). There were 42 babies admitted to ICU. The ICU survival was 37/42 (88.1%). Significant predictors of survival were place of birth (p value 0.006), mode of delivery (p value 0.007) and bag mask ventilation at birth (p value 0.040). The duration of stay (p value 0.000) was significantly longer in survivors (6.49 days SD 6.6). The remaining factors were not significantly different between the two groups. The rate of perinatal asphyxia (Apgar score <6) was 4.68 per 1000 live births; while 3.61 per 1000 live births had evidence of hypoxic ischaemic encephalopathy (HIE). Of the 390 babies discharged from CMJAH, 113 had follow up records (28.97%) to a mean corrected age of 5.88 months (SD 5.03). The majority (90/113 – 79.64%) had normal development. Conclusion: i) The high overall survival and survival after ICU admission provides a benchmark for further care. ii) Obtaining adequate data for long term follow up was not possible with the existing resources and surrogate early markers of outcome and / or more resources to ensure accurate follow-up are needed and iii) the high incidence of HIE suggest that a therapeutic hypothermia service including long-term follow-up component would be beneficial.
Books on the topic "Asphyxia neonatorum"
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J, Haddad, Saliba E. 1950-, and Arbeille Ph, eds. Perinatal asphyxia. Berlin: Springer-Verlag, 1993.
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Dev, Maulik, ed. Asphyxia and fetal brain damage. New York: Wiley-Liss, 1998.
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Richter, Tilman. Zur Asphyxia neonatorum des Kalbes: Biochemische Grundlagen und medikametelle Beinflussbarkeit. Hannover: [s.n.], 1989.
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Ruth, Vineta. Perinatal asphyxia: Biochemical parameters as indices of asphyxia at birth and predictors of brain damage, and a trial of preventing damage by phenobarbital. Helsinki: University of Helsinki, 1988.
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Association, British Paediatric, and Royal College of Obstetricians and Gynaecologists (Great Britain), eds. Resuscitation of the newborn. London: Royal College of Obstetricians and Gynaecologists, 1992.
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Symposium on Perinatal Asphyxia (1988 Toronto, Ont.). Perinatal asphyxia: Its role in developmental deficits in children : papers and discussion based on a symposium held October 26, 1988, in Toronto, Ontario, Canada, jointly with the 42nd Annual Meeting of the American Academy for Cerebral Palsy and Developmental Medicine and sponsored by the Canadian Medical Protective Association. Ottawa, Ontario: Canadian Medical Protective Association, 1988.
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Workshop on Acute Perinatal Asphyxia in Term Infants (1993 Rockville, Md.). Report of the Workshop on Acute Perinatal Asphyxia in Term Infants: August 30-31, 1993, Rockville, Maryland. [Washington, D.C.?]: The Institute, 1996.
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H, Haskell Guy, and Gausche-Hill Marianne, eds. Pediatric advanced life support: Pearls of wisdom : conforms to the American Heart Association guidelines 2000. Boston: Boston Medical Pub. Corp., 2001.
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Center for Devices and Radiological Health (U.S.), ed. Second draft proposed standard for the infant apnea monitor. Rockville, MD: Center for Devices and Radiological Health, Food and Drug Administration, 1989.
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Drew, David. Resuscitation of the newborn: A practical approach. Oxford: Butterworth-Heinemann, 2000.
Find full textBook chapters on the topic "Asphyxia neonatorum"
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Goldstein, Gary W. "New Therapies for Asphyxia Neonatorum and Intraventricular Hemorrhage of the Premature." In Perinatal Neurology and Neurosurgery, 57–65. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-011-7295-0_4.
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Saxena, Richa. "Asphyxia Neonatorum." In An Evidence-Based Clinical Textbook in Obstetrics and Gynaecology for MRCOG-2, 517. Jaypee Brothers Medical Publishers (P) Ltd., 2018. http://dx.doi.org/10.5005/jp/books/13055_55.
Full textConference papers on the topic "Asphyxia neonatorum"
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Yunita, Laurensia, Fadhiyah Noor Annisa, and Sundari Sundari. "Effect of Childbirth Complications Occurrence Of Asphyxia Neonatorum." In 2nd Sari Mulia International Conference on Health and Sciences 2017 (SMICHS 2017) � One Health to Address the Problem of Tropical Infectious Diseases in Indonesia. Paris, France: Atlantis Press, 2017. http://dx.doi.org/10.2991/smichs-17.2017.73.
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Syamsi, Efrida Yusriyanti, and Nuli Nuryanti Zulala. "Premature Rupture of Membrane (PROM) Increasing Asphyxia Neonatorum Risk." In International Conference on Health and Medical Sciences (AHMS 2020). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/ahsr.k.210127.053.
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Razak, Rahmatillah, and Asri Adisasmita. "Low Birth Weight and Asphyxia Neonatorum Risk: A Case-Control Study." In 2nd Sriwijaya International Conference of Public Health (SICPH 2019). Paris, France: Atlantis Press, 2020. http://dx.doi.org/10.2991/ahsr.k.200612.054.
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Rahmayanti, Ayu Lestari, Yulistiana Evayanti, Dessy Hermawan, and Ike Ate Yuviska. "THE FACTORS CONCERNING THE INCIDENCE OF ASPHYXIA ON MATERNITY WOMEN DURING THE COVID19 PANDEMIC AT Dr H ABDUL MOELOEK LAMPUNG PROVINCE HOSPITAL IN 2020." In International Conference on Public Health and Medical Sciences. Goodwood Conferences, 2022. http://dx.doi.org/10.35912/icophmeds.v1i1.28.
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The purpose of the study is to identify the factors concerning the incidence of asphyxia on maternity women during the Covid19 pandemic at Dr H Abdul Moeloek Lampung Province Hospital in 2021. The study is a correlational analytical survey with a case-control approach. The population of the study consisted of 244 neonates in which 122 of them became the samples. The objects of this study were maternal age, amniotic fluid, birth weight, umbilical cord entanglement, infection, partum age, newborns diagnosed with asphyxia neonatorum. The study was conducted at Dr H Abdul Moeloek Lampung Province Hospital in July 2021. Data collection technique was through observation sheet. The data analysis was univariate and bivariate. It was found that there was no relationship among maternal age (p value = 0.708), amniotic fluid (p-value = 0.896), birth weight (p value = 0.000), umbilical cord entanglement (0.370), infection (p value = 0.285) towards the incidence of asphyxia at Dr H Abdul Moeloek Lampung Province Hospital in 2021. Pregnant women should improve their knowledge about the risk factors of pregnant women and infants that may cause death. They are suggested to diligently check their pregnancy or ANC to know and monitor the condition of their babies