Dissertations / Theses on the topic 'ASIP'
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Šulek, Jakub. "Verifikace ASIP založena na formálních tvrzeních." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2015. http://www.nusl.cz/ntk/nusl-264941.
Full textKarlsson, Andréas. "Design of Energy-Efficient High-Performance ASIP-DSP Platforms." Doctoral thesis, Linköpings universitet, Datorteknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130723.
Full textShahabuddin, S. (Shahriar). "MIMO detection and precoding architectures." Doctoral thesis, Oulun yliopisto, 2019. http://urn.fi/urn:isbn:9789526222837.
Full textTiivistelmä Moni-tulo moni-lähtö (MIMO) -tekniikoita on sopeutettu kolmannen sukupolven (3G) langattomasta viestintästandardista alkaen spektritehokkuuden, tiedonsiirtonopeuden ja luotettavuuden parantamiseksi. MIMO-teknologioilla on useita hyviä puolia suhteessa peruskaistan vastaanottimeen, mutta samalla monimutkaisuus on lisääntynyt. VLSI-arkkitehtuurien tutkimus MIMO-signaalinkäsittelyssä on sen vuoksi herättänyt paljon kiinnostusta viimeisen kahden vuosikymmenen aikana. Myös MIMO:n saavuttama asema viidennen sukupolven (5G) viestintästandardin pääteknologiana on lisännyt kiinnostusta VLSI-arkkitehtuureihin MIMO-viestinnän tutkimuksessa. Tässä tutkielmassa on tutkittu erilaisia VLSI-arkkitehtuureja MIMO-signaalien tunnistus- ja esikoodausalgoritmeissa. Signaalien tunnistus ja esikoodaus ovat peruskaistaa käyttävän MIMO-vastaanottimen monimutkaisimmat osa-alueet. Tutkielmassa on keskitytty algoritmien ja arkkitehtuurien optimointiin ja esitetty useita VLSI-arkkitehtuureja MIMO-signaalien tunnistusta ja esikoodausta varten. Tutkielmassa on ehdotettu sovelluskohtaisen prosessorin (Application Specific Instruction-set Processor eli ASIP) käyttä pienen mittakaavan monimuotodetektorissa. Detektorin rakenne tukee samanaikaisesti keskineliöpoikkeaman minimointia (MMSE), SSFE (Selective Spanning with Fast Enumeration) -algoritmia ja LSD (List Sphere Detection) -algoritmia. Lisäksi tässä tutkielmassa ehdotetaan monisuoritinarkkitehtuuria hilan redusointialgoritmille (Lattice Reduction eli LR). LR-algoritmia varten ehdotetaan muokattua Lenstra-Lenstra-Lovasz (LLL) -algoritmia vähentämään alkuperäisen LLL-algoritmin monimutkaisuutta. Lisäksi MIMO-signaalien tunnistusalgoritmin perustaksi ehdotetaan vuorottelevaa kertoimien suuntaustapaa Alternating Direction Method of Multipliers eli ADMM). ADMM-perustaisesta taajuusvasteen rajoitetusta ääretön-normi-korjauksesta (infinity norm constrained equalization) käytetään nimitystä ADMIN-algoritmi. ADMIN-tunnistusalgoritmi toteutetaan sovelluskohtaisena integroituna piirinä (Application-Specific Integrated Circuit eli ASIC) ohjelmoitavaa porttimatriisia (Field Programmable Gate Array eli FPGA) varten. Lisäksi ehdotetaan ASIP-monimuotoesikooderin käyttöä. ASIP-esikooderin rakenne tukee normiperustaista aikataulutusta, QR-hajotelmaa, MMSE-esikoodausta ja likaisen paperin koodaukseen (Dirty Paper Coding eli DPC) perustuvaa esikoodausta
Sydow, Thorsten von [Verfasser]. "Modellbildung und Analyse heterogener ASIP-eFPGA-Architekturen / Thorsten von Sydow." Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2011. http://d-nb.info/1018226036/34.
Full textMurugappa, Velayuthan Purushotham. "Towards Optimized Flexible Multi-ASIP Architectures for LDPC/Turbo Decoding." Télécom Bretagne, 2012. http://www.telecom-bretagne.eu/publications/publication.php?idpublication=13220.
Full textLarge variety of channel coding techniques are specified in existing and emerging digital communication standards, each suitable for specific application needs (frame size, transmission channel, signal-to-noise ratio, bandwidth, etc). Considering the emerging multi-mode and multi-standard applications, as well as the increasing interest for Software Defined Radio (SDR) and Cognitive Radio (CR) applications, flexible implementations combining multiple error correction techniques becomes mandatory. However, the need of optimal solutions in terms of performance, area, and power consumption is increasing too and cannot be neglected against flexibility. In this context, this thesis work has investigated multi-ASIP architecture model towards the target of unifying flexibility-oriented and optimization-oriented approaches in the design of flexible channel decoders. By considering mainly the challenging Turbo and LDPC decoding applications, multi-ASIP channel decoder architectures are proposed targeting high flexibility combined with high architecture efficiency in terms of bits/cycle/iteration/mm2. Different architecture alternatives and design approaches are explored. Three original contributions have been proposed. The first one concerns the design of a scalable and flexible high throughput multi-ASIP LDPC/Turbo decoder. Several design objectives have been attained in this work in terms of scalability, resource sharing, and configurability speed. The proposed DecASIP supports the decoding of LDPC and Turbo codes specified in WiFi, WiMAX, and LTE standards. The achieved scalability through the multi-ASIP NoC based approach enables the accommodation of current and future high throughput requirements. The second contribution concerns the design of a parameterized ASIP for Turbo decoding (TDecASIP). Here the objective was to investigate the maximum attainable architecture efficiency for ASIP-based Turbo decoding when maximizing the usage of sub-block parallelism. Furthermore, with this architecture we demonstrated the possibility to design application-specific parameterized cores using the available ASIP design flow. The third contribution corresponds to the design of an optimized ASIP for LDPC decoding (LDecASIP). As for TDecASIP, the objective was to investigate the maximum attainable architecture efficiency for ASIP-based LDPC decoding by increasing the parallelism degree and the necessary memory bandwidth. A fourth main contribution of this thesis work concerns the hardware prototyping. A complete communication system platform including 4-DecASIP channel decoder has been prototyped on an FPGA-based logic emulation board. To our knowledge, this is the first demonstrated multi-ASIP NoC-based FPGA prototype that is capable of decoding LDPC and Turbo (SBTC and DBTC) codes. Furthermore, an ASIC integration of the 4-DecASIP system decoder has been accomplished by the CEA-LETI on the MAG3D Telecom chip which targets 4G communication applications. These results demonstrate the rapid design cycle and the effectiveness offered by the ASIP based design approach in this application domain to fine tune design trade-offs w. R. T. Diverse design objectives
Yu, Bin. "Scaffold study of ASIP and AgRP : antagonists of melanocortin system /." Diss., Digital Dissertations Database. Restricted to UC campuses, 2007. http://uclibs.org/PID/11984.
Full textSantos, Daniela Copetti. "Padrões de variabilidade do gene ASIP (agouti signaling protein) em mamíferos." Pontifícia Universidade Católica do Rio Grande do Sul, 2007. http://hdl.handle.net/10923/1294.
Full textO melanismo em mamíferos decorre principalmente da atividade de dois genes: MC1R (Melanocortin-1 Receptor), cujo produto induz a produção de eumelanina (pretomarrom); e ASIP (Agouti Signaling Protein), que codifica um peptídeo antagonista que promove a produção de feomelanina (pigmento claro). A combinação do efeito destes dois locos faz com que o pêlo cresça escuro com bandas subapicais amarelas. No presente estudo investigamos a diversidade nucleotídica e os padrões de variabilidade presentes no gene ASIP, principalmente nas regiões codificadoras dos éxons 2 e 3 e em regiões não codificadoras dos íntrons 2 e 3 em alguns mamíferos, com ênfase em felídeos (Mammalia, Carnivora, Felidae). Através do alinhamento entre as espécies analisadas nesse estudo foi possível construir três bases de dados que foram divididas em diferentes blocos conforme as regiões de alinhamento. A análise comparativa de seqüências permitiu a caracterização de diferentes blocos de seqüência conservada, assim como a identificação de uma inserção SINE presente apenas no gato doméstico, de uma região repetitiva hipervariável em todos os felídeos analisados, e também de variantes moleculares (SNPs) em Felis catus e Leopardus geoffroyi. Nenhum dos polimorfismos identificados nesta espécie estava localizado em regiões exônicas ou apresentou associação a fenótipos de coloração, indicando que as regiões analisadas não estão envolvidas na indução do melanismo nesta espécie.
Packiaraj, Vivek. "Study, Design and Implementation of an Application Specific Instruction Set Processor for a Specific DSP Task." Thesis, Linköping University, Electronics System, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-52314.
Full textThere is a lot of literature already available describing well-structured approach for embeddeddesign and implementation of Application Specific Integrated Processor (ASIP) micro processorcore.
This concept features hardware structured approach for implementation of processor core fromminimal instruction set, encoding standards, hardware mapping, and micro architecture design,coding conventions, RTL,verification and burning into a FPGA. The goal is to design an ASIPprocessor core (Micro architecture design and RTL) which can perform DSP task, e.g., FIR. Thereport is a well structured approach of design and implementation of an ASIP DSP processor forDSP applications like FIR. This report contains design flow starting from Instruction set design,micro architecture design and RTL implementation of the core. Details of the power simulationsof FPGA are also listed and analyzed.
Lapinskii, Viktor. "Algorithms for compiler-assisted design space exploration of clustered VLIW ASIP datapaths /." Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3008376.
Full textChan, Chun-Jung. "Investigation of NoGap : SIMD Datapath Implementation." Thesis, Linköpings universitet, Institutionen för systemteknik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-72131.
Full textYaochuan, Chen. "Binary Instruction Format Specification for NoGap." Thesis, Linköpings universitet, Datorteknik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-114199.
Full textSantos, Daniela Copetti. "Padr?es de variabilidade do gene ASIP (agouti signaling protein) em mam?feros." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2007. http://tede2.pucrs.br/tede2/handle/tede/5527.
Full textO melanismo em mam?feros decorre principalmente da atividade de dois genes: MC1R (Melanocortin-1 Receptor), cujo produto induz a produ??o de eumelanina (pretomarrom); e ASIP (Agouti Signaling Protein), que codifica um pept?deo antagonista que promove a produ??o de feomelanina (pigmento claro). A combina??o do efeito destes dois locos faz com que o p?lo cres?a escuro com bandas subapicais amarelas. No presente estudo investigamos a diversidade nucleot?dica e os padr?es de variabilidade presentes no gene ASIP, principalmente nas regi?es codificadoras dos ?xons 2 e 3 e em regi?es n?o codificadoras dos ?ntrons 2 e 3 em alguns mam?feros, com ?nfase em fel?deos (Mammalia, Carnivora, Felidae). Atrav?s do alinhamento entre as esp?cies analisadas nesse estudo foi poss?vel construir tr?s bases de dados que foram divididas em diferentes blocos conforme as regi?es de alinhamento. A an?lise comparativa de seq??ncias permitiu a caracteriza??o de diferentes blocos de seq??ncia conservada, assim como a identifica??o de uma inser??o SINE presente apenas no gato dom?stico, de uma regi?o repetitiva hipervari?vel em todos os fel?deos analisados, e tamb?m de variantes moleculares (SNPs) em Felis catus e Leopardus geoffroyi. Nenhum dos polimorfismos identificados nesta esp?cie estava localizado em regi?es ex?nicas ou apresentou associa??o a fen?tipos de colora??o, indicando que as regi?es analisadas n?o est?o envolvidas na indu??o do melanismo nesta esp?cie.
Richtarik, Pavel. "Rychlý a částečně překládaný simulátor pro aplikačně specifické procesory." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2018. http://www.nusl.cz/ntk/nusl-385970.
Full textPiscoya, Silva Ulises Abdon. "Diseño y simulación de un microprocesador de propósitos específicos (ASIP) utilizando el lenguaje de programacion VHDL." Universidad Nacional de Ingeniería. Programa Cybertesis PERÚ, 2006. http://cybertesis.uni.edu.pe/uni/2006/piscoya_su/html/index-frames.html.
Full textSkoglund, Björn. "Code profiling as a design tool for application specific instruction sets." Thesis, Linköping University, Department of Electrical Engineering, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8585.
Full textAs the embedded devices has become more and more generalized and as their product cycles keeps shrinking the field has opened up for the Application Specific Instruction set Processor. A mix between the classic generalized microcontroller and the specialized ASIC the ASIP keeps a set of general processing instructions for executing embedded software but combines that with a set of heavily specialized instructions for speeding up the data intense application core algorithms. One important aspect of the ASIP design flow
research is cutting design time and cost. One way of that is automation of the instruction set design. In order to do so a process is needed where the algorithm to be ASIPed is analyzed and critical operations are found and exposed so that they can be implemented in special hardware. This process is called profiling. This thesis describes an implementation of a fine grained source code profiler for use in an ASIP design flow. The profiler software is based on a static-dynamic workflow where data is assembled from both static
analysis and dynamic execution of the program and then analyzed together in an specially made analysis software.
Nilsson, Anders. "Design of programmable multi-standard baseband processors." Doctoral thesis, Linköping : Department of Electrical Engineering, Linköping University, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8908.
Full textReichel, Peter. "Effizienter Einsatz von Bildsensoren mit integrierter Signalverarbeitung." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-227708.
Full textCousin, Jean-Gabriel. "Methodologies de conception de coeurs de processeurs specifiques (asip) : mise en oeuvre sous contraintes, estimation de la consommation." Rennes 1, 1999. http://www.theses.fr/1999REN10085.
Full textEusse, Giraldo Juan Fernando [Verfasser], Rainer [Akademischer Betreuer] Leupers, and Holger [Akademischer Betreuer] Blume. "ASIP algorithmic/architectural co-exploration based on high level performance estimation / Juan Fernando Eusse Giraldo ; Rainer Leupers, Holger Blume." Aachen : Universitätsbibliothek der RWTH Aachen, 2019. http://d-nb.info/1220359505/34.
Full textLundgren, Björn, and Anders Ödlund. "Exposure of Patterns in Parallel Memory Acces." Thesis, Linköping University, Department of Electrical Engineering, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-9795.
Full textThe concept and advantages of a Parallel Memory Architecture (PMA) in computer systems have been known for long but it’s only in recent time it has become interesting to implement modular parallel memories even in handheld embedded systems. This thesis presents a method to analyse source code to expose possible parallel memory accesses. Memory access Patterns may be found, categorized and the corresponding code marked for optimization. As a result a PMA compatible with found pattern(s) and code optimization may be specified.
Radhakrishnan, Swarnalatha Computer Science & Engineering Faculty of Engineering UNSW. "Heterogeneous multi-pipeline application specific instruction-set processor design and implementation." Awarded by:University of New South Wales. Computer Science and Engineering, 2006. http://handle.unsw.edu.au/1959.4/29161.
Full textLéonardon, Mathieu. "Décodage de codes polaires sur des architectures programmables." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0399/document.
Full textPolar codes are a recently invented class of error-correcting codes that are of interest to both researchers and industry, as evidenced by their selection for the coding of control channels in the next generation of cellular mobile communications (5G). One of the challenges of future mobile networks is the virtualization of digital signal processing, including channel encoding and decoding algorithms. In order to improve network flexibility, these algorithms must be written in software and deployed on programmable architectures.Such a network infrastructure allow dynamic balancing of the computational effort across the network, as well as inter-cell cooperation. These techniques are designed to reduce energy consumption, increase through put and reduce communication latency. The work presented in this manuscript focuses on the software implementation of polar codes decoding algorithms and the design of programmable architectures specialized in their execution.One of the main characteristics of a mobile communication chain is that the state of communication channel changes over time. In order to address issue, adaptive modulationand coding techniques are used in communication standards. These techniques require the decoders to support a wide range of codes : they must be generic. The first contribution of this work is the software implementation of generic decoders for "List" polar decoding algorithms on general purpose processors. In addition to their genericity, the proposed decoders are also flexible. Trade-offs between correction power, throughput and decodinglatency are enabled by fine-tuning the algorithms. In addition, the throughputs of the proposed decoders achieve state-of-the-art performance and, in some cases, exceed it.The second contribution of this work is the proposal of a new high-performance programmable architecture specialized in polar code decoding. It is part of the family of Application Specific Instruction-set Processors (ASIP). The base architecture is a RISC processor. This base architecture is then configured, its instruction set is extended and dedicated hardware units are added. Simulations show that this architecture achieves through puts and latencies close to state-of-the-art software implementations on generalpurpose processors. Energy consumption is reduced by an order of magnitude. The energy required per decoded bit is about 10 nJ on general purpose processors compared to 1nJ on proposed processors when considering the Successive Cancellation (SC) decoding algorithm of a polar code (1024,512).The third contribution of this work is also the design of an ASIP architecture. It differs from the previous one by the use of an alternative design methodology. Instead of being based on a RISC architecture, the proposed processor architecture is part of the classof Transport Triggered Architectures (TTA). It is characterized by a greater modularity that allows to significantly improve the efficiency of the processor. The measured flowrates are then higher than those obtained on general purpose processors. The energy consumption is reduced to about 0.1 nJ per decoded bit for a polar code (1024,512) with the SC decoding algorithm. This corresponds to a reduction of two orders of magnitude compared to the consumption measured on general purpose processors
Qin, An. "Design and Implementation of a Source Code Profiling Toolset for Embedded System Analysis." Thesis, Linköpings universitet, Datorteknik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-63525.
Full textHepp, Diego. "Influência dos genes candidatos MC1R, ASIP, TYRP1 e kit na pigmentação em ovinos crioulos e predição do efeito dos polimorfismos não sinônimos no gene MC1R humano." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/119623.
Full textAnimal color is a characteristic that presents a large diversity of phenotypes. Different approaches can be used to understand the color diversity existing among and within species. Through analysis of candidate genes the mutations responsible for the color variation have been described in different species, showing the involvement of various molecular mechanisms of regulation. The objective of this work is the use of two genetic approaches to the study of color variation, the analysis of candidate genes and the computational prediction of non-synonym polymorphism effects (nsSNPs). In sheep the wool color is a feature with commercial importance and in identifying breeds. Polymorphisms in different genes have been associated with wool color, but they have not been studied in many breeds that show phenotypic variation regarding such a charactere. The Creole is a local breed from southern most Brazil that presents a wide range of wool color, varying from white to black, and including several intermediate hues. The melanocortin 1 receptor (MC1R) was previously associated with the wool color in the Creole, however, other genes might also be involved in the regulation of color in the breed. This study evaluated the influence of the genes MC1R, ASIP (agouti signaling protein), TYRP1 (tyrosinase related protein 1) and KIT (v-kit Hardy- Zuckerman 4 feline sarcoma viral oncogene homolog) in the Creole breed wool color. Samples from 410 specimens of different colors were analyzed. The variation in the color of the wool was performed by colorimetry. The inheritance pattern of the phenotypes was assessed by crossbreeding individuals of different colors. Polymorphisms in the genes were evaluated by performing sequencing and fragment analysis, and the quantification of the ASIP gene expression was performed by Real Time-PCR. It was observed a significant association between polymorphisms in MC1R and ASIP gene and the wool color in Creole breed. The dominant allele of the MC1R gene, caused by p.M73K and p.D121N mutations was found only in pigmented individuals. This allele leads to the constitutive activation of the receptor and therefore in constant production of eumelanin and is epistatic on the ASIP gene. In the homozygous to the wild-type allele of MC1R the manifestation of white phenotype occurred only in individuals with one allele containing a duplication of the ASIP gene. The carriers of the duplicated copy of ASIP showed high levels of gene expression while homozygous for the simple copy of the ASIP did not expressed the gene, and showed pigmented phenotypes. The results allowed the identification of the influence of epistatic interaction of MC1R and ASIP gene in the wool color in Creole breed. The study of candidate genes involved in the pigmentation pathway proved to be a suitable approach for the analysis of variation in pigmentation in these animals. It is expected that the knowledge acquired in this work will assist on stablishment of commercial breeding and preservation policies of this sheep breed. The computational evaluation of non-synonymous polymorphism has been used to determine SNPs that potentially affect the function of the genes and identify the mechanisms responsible for complex diseases and by the variation in phenotypes. The prediction of the effect of polymorphisms in genes using computational tools presents an alternative approach to the study of the genetic of coloration. The human MC1R gene has a large number of know polymorphisms, some of which were associated with changes in pigmentation and susceptibility to skin tumors. However, many existing variations in the gene have not been evaluated regarding the functional consequences and its role in the variation of pigmentation. Computational prediction of nonsynonymous polymorphisms was performed in the human MC1R gene in order to identify the most likely harmful nsSNPs and to establish those with potential effect on the function of MC1R. Eleven individual tools (SIFT, MutPred, Polyphen-2, PROVEAN, I-Mutant 3.0, PANTHER, SNPs3D, Mutation Assessor, PhD-SNP, SNPs&GO and SNAP) and two consensus programs (PON-P and PredictSNP 1.0) were used to the analysis of 92 nsSNPs located in the gene. The programs used are based in evolutionary, structural and computational methods, resulting in the identification of the 14 most damaging nsSNPs (L48P, R67W, H70Y, P72L, S83P, R151H, S172I, L206P, T242I, G255R, P256S, C273Y, C289R and R306H). Despite the differences in the results of the each program the combination of different methods allowed the differentiation of the neutral polymorphisms from the most damaging, showing agreement with the consensus programs. The computational prediction has proved to be an efficient approach for the identification of harmful alleles in the MC1R gene and for the prioritization of mutations for further functional and population studies.
Mikó, Albert. "Akcelerace aplikací pomocí specializovaných instrukcí." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2016. http://www.nusl.cz/ntk/nusl-255444.
Full textAkhlaq, Faisal, and Sumathi Loganathan. "Assembler Generator and Cycle-Accurate Simulator Generator for NoGAP." Thesis, Linköping University, Department of Computer and Information Science, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-56999.
Full textSystem-on-Chip is increasingly built using ASIP(Application Specific Instruction set Processor) due to the flexibility and efficiency obtained from ASIPs. NoGAP (Novel Generator of Accelerator and Processor framework) is an innovative approach for ASIP design, which provides the advantage of both ADL (Architecture Description Language) and HDL (Hardware Description Language) to the designer.
For the processors designed using NoGAP, software tools need to be automatically generated, to aid the designer in programming and verifying the processor. As part of the master thesis work, we have developed two generators namely Assembler generator and Cycle-Accurate Simulator generator for NoGAP using C++. The Assembler generator automatically generates an assembler, which is used to convert the assembly code written by a programmer into relocatable binary code. The Cycle-Accurate Simulator generator automatically generates a cycle-accurate simulator to model the behavior of the designed processor. Both these generators are static, and can be used to generate the tools for any processor created using NoGAP.
In this report, we have detailed the concepts behind the generators,and the implementation details of the generators. We have listed the results obtained from running assembler and cycle-accurate simulator on a test processor created using NoGAP.
NoGAP
McRobie, Helen R. "The genetic and molecular basis of melanism in the grey squirrel (sciurus carolinensis)." Thesis, Anglia Ruskin University, 2014. https://arro.anglia.ac.uk/id/eprint/576178/1/The%20Genetic%20and%20Molecular%20Basis%20of%20Melanism%20in%20the%20Grey%20Squirrel%20Helen%20McRobie.pdf.
Full textMcRobie, Helen R. "The genetic and molecular basis of melanism in the grey squirrel (Sciurus carolinensis)." Thesis, Anglia Ruskin University, 2014. http://arro.anglia.ac.uk/576178/.
Full textLemos, Ana Cláudia Cavalcante Espósito [UNESP]. "Estudo histomorfométrico, ultraestrutural e da expressão de Wnt1, WIF-1 e ASIP na pele com melasma em comparação com a pele sã perilesional e retroauricular." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/151232.
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O melasma é hipermelanose crônica e adquirida decorrente de um complexo processo que envolve hipertrofia melanocítica e disfunção melanogênica. Acomete preferencialmente o sexo feminino e as lesões ocorrem nas áreas fotoexpostas, especialmente a face. Sua patogênese não é bem compreendida e os estudos clássicos avaliam apenas pele acometida e perilesional, mas pouco se sabe do comportamento da pele fotoprotegida, submetida aos mesmos fatores sistêmicos e genéticos. Neste estudo, objetivamos avaliar características histológicas, vias epidérmicas que influem na melanogênese (Wnt e ASIP) e características ultraestruturais da pele com melasma em comparação com a pele sã adjacente e retroauricular. Para a execução deste estudo transversal com controle intra-sujeito, foram coletadas três biópsias cutâneas (punch 3 mm) de onze mulheres com melasma facial. As áreas de coleta foram a pele com melasma, pele sã adjacente (distando no máximo 2 cm do limite da lesão) e pele retroauricular ipsilateral. Os fragmentos provenientes de dez participantes foram corados por hematoxilina-eosina, ácido periódico de Schiff, Fontana-Masson, picrosirius red, azul de toluidina e Verhöff; imunomarcados para CD34 e submetidos à imunofluorescência direta (IFD) de dupla marcação para proteínas Wnt1, WIF-1 e ASIP. Já os três fragmentos de uma das participantes foram processados para Microscopia Eletrônica de Transmissão (MET). Os dados obtidos foram comparados entre as topografias por modelo linear generalizado de efeitos mistos. As participantes eram fototipo III ou IV de Fitzpatrick, com idade média (desvio-padrão) de 42,9 (8,9) anos e apresentavam lesões há 16,7 (7,9) anos. Houve adelgaçamento da camada córnea na pele com melasma e na pele adjacente. Na pele com melasma houve maior compactação da córnea, maior pigmentação melânica epidérmica, maior heterogeneidade do colágeno, elastose solar, maior número de mastócitos, falhas da integridade da zona da membrana basal, melanócitos em pêndulo, bem como maior celularidade e vasos na derme superficial. IFD evidenciou maior intensidade de marcação de Wnt1 na pele com melasma em relação à pele adjacente e maior intensidade na pele retroauricular em relação à pele sã adjacente. Não houve diferença estatística significativa na intensidade de marcação de WIF-1 e ASIP entre as topografias. À MET, houve maior dano estrutural na lâmina lúcida no melasma, bem como maior número de melanossomas maduros e organelas citoplasmáticas nos melanócitos e queratinócitos basais. Tais resultados evidenciam que a pele com melasma apresenta, além da hipertrofia melanocítica, alterações na barreira epidérmica, na derme superior, zona de membrana basal e maior ativação da via Wnt, que diferem da pele fotoexposta adjacente e da retroauricular, configurando um fenótipo individualizado e não somente uma extensão do fotoenvelhecimento ou do envelhecimento intrínseco.
Melasma is a chronic and acquired hypermelanosis resulting from a complex process which involves melanocytic hypertrophy and melanogenic dysfunction. Melasma mainly affects females and lesions occur in the photoexposed areas, especially the face. Its pathogenesis is not well understood, and classical studies evaluate only the affected and perilesional skin, but little is known about the behavior of the non-sun-exposed skin, subjected to the same systemic and genetic factors. In this study, we aimed to evaluate histological features, epidermal pathways that influence melanogenesis (Wnt and ASIP) and ultrastructural characteristics of the skin with melasma in comparison to healthy adjacent and retroauricular skin. For the execution of this cross-sectional study with intrasubject control, three skin biopsies (punch 3 mm) were collected from eleven women with facial melasma. The areas of collection were the skin with melasma, adjacent healthy skin and retroauricular skin. Fragments from ten participants were stained with hematoxylin-eosin, periodic acid from Schiff, Fontana-Masson, picrosirius red, toluidine blue and Verhöff; immunomarked for CD34 and subjected to double-labeled direct immunofluorescence (DIF) for Wnt1, WIF-1 and ASIP proteins. The three fragments of one of the participants were processed for Transmission Electron Microscopy (TEM). The data obtained were compared between topographies by generalized linear model of mixed effects. Participants were Fitzpatrick's phototype III or IV; the mean age (standard deviation) was 42.9 (8.9) years and they had lesions for 16.7 (7.9) years. There was thinning of the corneal layer on the skin with melasma and adjacent skin. In the skin with melasma, there was more corneal compaction, greater epidermal melanic pigmentation, greater collagen heterogeneity, solar elastosis, more mast cells, defects of the basement membrane area, pendulum melanocytes, as well as greater cellularity and vessels in the superficial dermis. DIF showed a greater intensity of Wnt1 marking in the skin with melasma in relation to the adjacent skin, and greater intensity in the retroauricular skin in relation to the adjacent healthy skin. There was no significant statistical difference in the intensity of WIF-1 and ASIP marking between topographies. At TEM, there was more structural damage to the lamina lucida in melasma, as well as more mature melanosomes and cytoplasmic organelles in melanocytes and basal keratinocytes. These results show that melasma skin presents, in addition to melanocytic hypertrophy, alterations in the epidermal barrier, upper dermis, basement membrane zone and greater activation of the Wnt pathway, which differ from adjacent and retroauricular photoexposed skin, forming an individualized phenotype and not only an extension of photoaging or intrinsic aging.
Lemos, Ana Cláudia Cavalcante Espósito. "Estudo histomorfométrico, ultraestrutural e da expressão de Wnt1, WIF-1 e ASIP na pele com melasma em comparação com a pele sã perilesional e retroauricular." Botucatu, 2017. http://hdl.handle.net/11449/151232.
Full textResumo: O melasma é hipermelanose crônica e adquirida decorrente de um complexo processo que envolve hipertrofia melanocítica e disfunção melanogênica. Acomete preferencialmente o sexo feminino e as lesões ocorrem nas áreas fotoexpostas, especialmente a face. Sua patogênese não é bem compreendida e os estudos clássicos avaliam apenas pele acometida e perilesional, mas pouco se sabe do comportamento da pele fotoprotegida, submetida aos mesmos fatores sistêmicos e genéticos. Neste estudo, objetivamos avaliar características histológicas, vias epidérmicas que influem na melanogênese (Wnt e ASIP) e características ultraestruturais da pele com melasma em comparação com a pele sã adjacente e retroauricular. Para a execução deste estudo transversal com controle intra-sujeito, foram coletadas três biópsias cutâneas (punch 3 mm) de onze mulheres com melasma facial. As áreas de coleta foram a pele com melasma, pele sã adjacente (distando no máximo 2 cm do limite da lesão) e pele retroauricular ipsilateral. Os fragmentos provenientes de dez participantes foram corados por hematoxilina-eosina, ácido periódico de Schiff, Fontana-Masson, picrosirius red, azul de toluidina e Verhöff; imunomarcados para CD34 e submetidos à imunofluorescência direta (IFD) de dupla marcação para proteínas Wnt1, WIF-1 e ASIP. Já os três fragmentos de uma das participantes foram processados para Microscopia Eletrônica de Transmissão (MET). Os dados obtidos foram comparados entre as topografias por modelo linear generali... (Resumo completo, clicar acesso eletrônico abaixo)
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Cheung, Newton Computer Science & Engineering Faculty of Engineering UNSW. "Design automation methodologies for extensible processor platform." Awarded by:University of New South Wales. School of Computer Science and Engineering, 2005. http://handle.unsw.edu.au/1959.4/26118.
Full textEngroff, Alian Moreira. "Asipampium: uma ferramenta de desenvolvimento automático de processadores de aplicação específica." Universidade Federal do Pampa, 2017. http://dspace.unipampa.edu.br:8080/jspui/handle/riu/2031.
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Nas ultimas décadas houve um crescimento exponencial no desenvolvimento de sistemas embarcados, que são alocados no mais diversos equipamentos como eletrodomésticos e eletrônicos portáteis. Os sistemas embarcados são compostos por processadores de uso geral ou especıfico, os quais são desenvolvidos para cada sistema, apresentando restrições quanto ao custo de área, consumo de energia e tempo de processamento. Essas restrições dependem da aplicação e das funcionalidades. Dentre vários tipos de metodologias de projeto que buscam atender´ as necessidade de desenvolvimento de processadores para esses equipamentos, destaca-se a metodologia de desenvolvimento ASIP, do inglêsˆ Application Specific Integrated Processor. Os ASIPs são desenvolvidos de forma otimizada para cada aplicação, com um conjunto de instruções, tipos de memoria, quantidade e formas de acesso customizados. No entanto, a otimização do hardware implica em muito esforço para o desenvolvimento do processador. Nesse sentido, e necessário uma plataforma de desenvolvimento automático de ASIPs que analise o programa, as restrições da aplicação, e também forneça suporte a simulação e compilação. Este trabalho tem como objetivo principal elaborar uma ferramenta para o desenvolvimento automático de processadores de aplicação especıfica chamada ASIPAMPIUM, buscando tornar o desenvolvimento de um ASIP fácil e rápido com uma boa relação entre custo de área, consumo de potencia e velocidade de processamento. Para isso, foi proposta uma arquitetura de um processador reconfigurável, chamado PAMPIUM, que e definida como uma arquitetura RISC com 80 instruções, utilizando operações apenas com registradores. Esta arquitetura e utilizada como base para o ASIP, pois ela possui a flexibilidade necessária para se adaptar as características das mais diversas aplicações. A utilização de uma arquitetura base permite que o usuário possa desenvolver ASIPs para as mais variadas aplicações utilizando uma mesma plataforma de desenvolvimento. O processador gerado pelo ASIPAMPIUM e disponível em linguagem de descrição hardware, de forma que possa ser sintetizado para a fabricação de circuitos integrados ou para gravação em FPGA. Para o desenvolvimento do ASIP são utilizadas três versões base do PAMPIUM: monociclo, pipeline e superescalar. Desta forma o processador gerado leva em consideração as principais estatísticas do compilador e do simulador. Para validação a ferramenta ASIPAMPIUM foi utilizada no desenvolvimento de uma FFT e comparadas suas características com outros trabalhos, mostrando uma boa equivalência nos resultados. Também foi desenvolvido um sistema de controle de uma rede de antenas retrodiretivas. Este sistema foi testado e validado em FPGA. Além disso, foi elaborada uma versão do PAMPIUM em silício, denominada PAMPIUM IC, a qual foi prototipada em tecnologia 0 ,18µm da TSMC, testada e validada eletricamente. Estas aplicações demonstram o correto funcionamento da metodologia proposta, gerando hardware de alto desempenho com um curto tempo de desenvolvimento.
In the last years there has been an exponential increase in the development of embedded systems, which are used in the most diverse equipment such as home appliances and portable electronics. Embedded systems are made up of processors of specific or general purpose. Specific processors are developed for each system, with restrictions on area, energy consumption and processing time. These restrictions are depend on the application and the features. Among several types of design methodologies for the development of processors for these equipments, stands out the development methodology for Application Specific Integrated Processors (ASIPs). ASIPs are optimally developed for each application, with a set of instructions, types of memory, quantity and custom access forms. However, the optimization of the hardware implies a lot of effort for the development of the processor. It is also necessary to develop a set of tools, such as compilers and simulators for ASIP. In that sense an automatic ASIP development platform is needed that analyzes the program, the application restrictions, and also provides support for simulation and compilation. This work has as main objective to elaborate a tool for the automatic development of specific application processors called ASIPAMPIUM. This tool seeks to make the development of an ASIP easy and fast, with a good relation between area, power consumption and processing speed. For this, a reconfigurable processor architecture, called PAMPIUM, was proposed, which is defined as a RISC architecture with 80 instructions, using register operations only. This architecture is used as the basis for ASIP, since it has the necessary flexibility to adapt to the characteristics of the most diverse applications. The use of a base architecture allows the user to develop ASIPs for the most varied applications using the same development platform. The processor generated by ASIPAMPIUM is available in hardware description language, so that it can be synthesized for the manufacture of integrated circuits or for FPGA implementation. Three basic versions of PAMPIUM are used: monocycle, pipeline and superscalar. In this way the generated processor takes into account the main compiler and simulator statistics. For validation, the ASIPAMPIUM tool was used in the development of an FFT and compared its characteristics with other works, showing a good equivalence in the results. Also has been developed control system for a retrodirective antennas array. This system has been tested and validated in FPGA. In addition, a version of PAMPIUM in silicon, called PAMPIUM IC, was developed, which was prototyped in TSMC 0 ,18µ technology, tested and validated electrically. These applications demonstrate the correct functioning of the proposed methodology, generating high performance hardware with a short development time.
Bourgeois, Yann. "Génétique évolutive d'un cas extrême de polymorphisme de la coloration du plumage chez un oiseau insulaire, Zosterops borbonicus (Zosteropideae)." Toulouse 3, 2013. http://www.theses.fr/2013TOU30333.
Full textColor polymorphisms are of considerable interest in evolutionary biology. As they are accessible and involved in a variety of selective processes, they have contributed significantly to our understanding of biological diversity. We studied a case of polymorphism at a small spatial scale in Zosterops borbonicus, using indirect approaches such as population genetics and genomics. It appears that coloration changes are not due to genes classically described as 'evolutionary hotspots'. We also identified a locus linked to coloration on chromosome 1. This locus is not yet described as affecting feathers or hair coloration. High effective population sizes and moderate gene flow have probably favored selective effects in shaping this polymorphism. This study illustrates how indirect approaches can allow inferring the context in which phenotypic diversity occurs
Andriamisaina, Choukataly Caaliph. "Synthèse d'architecture multi-modes pour les applications du traitement du signal et de l'image." Lorient, 2008. http://www.theses.fr/2008LORIS127.
Full textEmerging standards lead an increasing demand for high performance, flexibility and low power of embedded systems. These requirements had led to the research on efficient devices to respect these constraints. To have a good trade-off between flexibility and performance, adding flexibility to dedicated architectures and/or improving software performances can be considered. In the literature, the architectures, which result from the addition of flexibility in dedicated architectures, are named multi-modes architectures. The multi-modes or multi-configurations architectures are specifically designed for a set of time-wise mutually exclusive applications (multi-standard applications). They are also used to reduce the reconfiguration time overhead in FPGAs and to implement loop accelerators. We propose a design methodology, based on the High-Level Synthesis (HLS) technique, dedicated to the multi-modes architectures generation. The high-level synthesis is a technique, which considerably increase the productivity by raising the level of abstraction of the input specification and by automating the design. In the context of HLS, we propose to modify the allocation, scheduling and binding steps in order to reduce the area cost of the generated architecture by limiting the performance and power consumption overhead. In order to obtain an area efficient multi-modes architecture, we propose to reduce the area cost of the datapath and the controller. The controller complexity reduction is obtained by increasing the resources similarity between the control steps of the different modes. Whereas, the datapath complexity reduction is obtained by the resources sharing between the modes, and by the consideration of the interconnections cost during this sharing. This approach was integrated in a design environment, dedicated to the multi-modes architectures generation. This environment is based on different tools: GAUT “Multi-modes”, CDFG2UCOM and STARGene “Multi-modes”. It takes as input a functional description specified in C/C++ language in order to obtain automatically a multi-modes architecture at register transfer level described in VHDL. A set of experiment has been done to show the effectiveness of our approach and its associated high-level synthesis tools. From these experiments, we notice that with our approach, we can greatly reduce (up to 60%) the area occupied by the different modes to implement. With this important area reduction, we also obtain a low performance (average of 5%) and power consumption (average of 16%) overhead
Carro, Luigi. "Algoritmos e arquiteturas para o desenvolvimento de sistemas computacionais." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 1996. http://hdl.handle.net/10183/17780.
Full textThis work discusses architectures and algorithms for the development of computational systems, which are based on a microprocessor (custom or off-the-shelf), the set of application programs and a dedicated HW, used to increase the performance of the whole system. The goal of this work is to show that, nowadays, the division line between SW and HW is smooth, and the transition from one to the other can be achieved by the system designer using a specific CAD in order to obtain a trade-off between cost and performance. The CAD environment is presented, followed by routine classification and optimization methods based on the former classification to increase the performance of the system. Techniques devoted to systems based on dedicated Risc processors are showed next, to optimize certain type of programs. Positive results are shown for a set of examples. Since the Brazilian electronics market is strongly based on microcontrollers, the study and results of optimization techniques regarding this type of systems are also presented. The same techniques can be applied to dedicated processors as well. Results of this proposal are obtained for a set of real world examples. The last topic of this work regards the validation of computational systems, mainly those presented throughout this work.
Rochus, Christina. "Diversité génétique du mouton domestique : exemple de populations suédoises et françaises." Thesis, Paris, Institut agronomique, vétérinaire et forestier de France, 2017. http://www.theses.fr/2017IAVF0008.
Full textDomestic sheep are raised for meat, milk and fibre production and are found all around the world in many types of environments. Sheep have been shown to be genetically diverse but this genetic diversity has not been fully described: there are still many sheep populations which have not yet been studied. The purpose of this thesis was to study genetic diversity in Swedish and French sheep breeds using high density marker arrays. Additional methods, including genotyping of microsatellite markers, and endogenous retroviruses and pedigree information were used to study Swedish sheep populations. Inbreeding and heterozygosity estimated in Gute sheep using the pedigree of the entire registered Swedish population and additionally microsatellite genotypes and pedigree from a sample of the population (N=94) indicated a breeding program with the purpose of reducing inbreeding. Studying genetic relationships among breeds by genotyping endogenous retroviruses indicated Klövsjö, Värmland, Finewool, Gute and Roslag sheep breeds had characteristics of primitive breeds (absence of retroviruses or presence of the specific retrovirus event enJSRV-7) although Finewool, Gute and Roslag sheep breeds had moderate frequencies of enJSRV-18 which is indicative of more modern sheep breeds. Studying variants in two coat colour genes, ASIP and MC1R, and their association with black coat colour revealed different selection histories in five Swedish sheep breeds studied. Studying the population structure of Dalapäls, Fjällnäs, Gotland, Gute and Klövsjö sheep, using high density SNP genotyping revealed that these breeds are genetically distinct breeds. When comparing with other European breeds and south west Asian breeds, they grouped with other north European short-tailed sheep breeds and they had generally accumulated more drift than breeds from other geographical areas. Studying 27 French breeds with high density genotypes revealed that French sheep populations harbour much of European sheep diversity in a small geographic area. Selective sweeps identified: selection hotspots, selection targets in many species; introgression of an adaptive allele; and allelic heterogeneity, which was confirmed with targeted resequencing of a coat colour gene, MC1R, in breeds under selection
Milliot, David. "Processus ASEM (Asia-Europe meeting) : vers l'émergence du trans-régionalisme Asie-Europe ?" Paris 10, 2003. http://www.theses.fr/2003PA100025.
Full textThe launching of the ASEM process in Bangkok in 1996 was the first step towards a global agenda among two equal partners, Asia and Europe. Supported by specific working procedures and biannual summits, ASEM has created a new dynamic between the two regions. From ASEM I in Bangkok (1996) to ASEM IV in Copenhaguen (2002), ASEM has developed a complete new set of methods of fostering political and economic dialogue as well as functional co-operation. Its working, achievements and shortcomings are analysed. But the key question is : what both partners want to achieve through this process ? First, ASEM aims at increasing the profile of Asia and Europe in international relations. But it also underlines a number of functions which help States managing their bilateral, inter-regional and multilateral affairs. The trans-regionalism of ASEM is in fact an important feature of this new process. As a political and diplomatic process, ASEM is to a large extent more influenced by the informal Asian ways of conducting business than the legalistic European approach. The consequences of the ASEM process on Asian regionalism, especially the building-up of an East-Asian Community, are also to be considered. Whereas Southeast Asia is searching ways to consolidate its position in the context of emerging China and the increasing dynamism of the Indian subcontinent, ASEM provides with new linkages. The role of the ASEM process in the international affairs is not meaningless : it has emerged as being a new layer of co-operation and has created a window of opportunity for fostering new types of co-operation between regions in the world. In fact, ASEM has served as a blueprint respectively for Europe and Asia to foster new relations with other regions (Latin America, Africa, Middle East). Hence, it raises the issue of a new global governance in international relations. Will ASEM be the missing link between regionalism and globalization ?
Martin, Kevin. "Génération automatique d'extensions de jeux d'instructions de processeurs." Phd thesis, Université Rennes 1, 2010. http://tel.archives-ouvertes.fr/tel-00526133.
Full textJanáková, Zuzana. "Čínska soft power v ázijskom regióne." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-16060.
Full textFloc'h, Antoine. "Compilation optimisante pour processeurs extensibles." Phd thesis, Université Rennes 1, 2012. http://tel.archives-ouvertes.fr/tel-00726420.
Full textSvoboda, Jan. "ASEAN a perspektivy jeho vnější integrace." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-74029.
Full textZmijanović, Katarina. "Regionalismus v rozvojové Asii." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-75151.
Full textPešková, Veronika. "Obchodní vztahy EU s asijskými státy." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-124583.
Full textRegent, Kamil. "Ekonomický rozvoj jihoasijských zemí." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-162795.
Full textBarták, Jiří. "Model procesoru RISC-V." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2016. http://www.nusl.cz/ntk/nusl-255393.
Full textRevire, Nicolas. "The Enthroned Buddha in Majesty : an Iconological Study." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCA157/document.
Full textThis dissertation provides a detailed study of a particular representation of the Buddha, in which he sits on a prominent throne, i.e. a bhadrapīṭha or bhadrāsana, in a majestic posture with two legs pendant, that is, in bhadrāsana or the “auspicious pose.” This pendant-legged imagery, generally associated with the throne, has been found widely depicted in South, East, and Southeast Asian art and is, as a rule, mostly associated with kingship, fertility, and even divinity. The results of this iconological examination have wide implications for understanding the origins, spread, and development of Buddhist art in those lands, particularly during the first millennium CE
Konieczná, Ewa. "Politika rozvojové spolupráce EU se zeměmi Jižní a Jihovýchodní Asie." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-85885.
Full textPetr, Zdeněk. "Dovoz potravin ze států východní Asie." Master's thesis, Vysoká škola ekonomická v Praze, 2015. http://www.nusl.cz/ntk/nusl-205910.
Full textNájera, Rendón Daniel. "Asia Town + Casa Asia Puebla." Thesis, Universidad de las Américas Puebla, 2011. http://catarina.udlap.mx/u_dl_a/tales/documentos/lar/najera_r_d/.
Full textHojzáková, Věra. "East Asia's Security System." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-162792.
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