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1
Gallagher, Mark. "Crazy Rich Asians and pan-Asian screen cosmopolitanism." East Asian Journal of Popular Culture 6, no. 2 (August 1, 2020): 195–215. http://dx.doi.org/10.1386/eapc_00025_1.
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Crazy Rich Asians (2018), a box-office hit in North America, provoked celebration particularly from Asian American commentators and actors. Shot in Singapore and Malaysia with an Asian and Asian American cast, it was a success too in Singapore itself and in territories such as Hong Kong, Taiwan and Australia but not in East Asia’s largest markets, those of China, Japan and South Korea. Focusing on the phenomenon of Crazy Rich Asians’ release, particularly its engagement with and circulation in East and Southeast Asia and its polarized reception among different Asian American and Asian communities, this article traces a series of discursive flashpoints to understand the film’s position in Asian and Asian American film culture. Arguing that the fortunes of US releases with Asian and Asian American casts reveal cosmopolitanism’s invisible borders, the article proposes a model of pan-Asian screen cosmopolitanism. This model recognizes that even globally hybrid screen texts such as Crazy Rich Asians bear cultural markers that may inhibit their appeal in territories with shared ethnic heritages but discrete social histories.
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Ahn, Myung-Ju, HyeRyun Kim, James Chih-Hsin Yang, Ji-Youn Han, Jong Seok Lee, Maximilian J. Hochmair, Jacky Yu-Chung Li, et al. "Brigatinib (BRG) versus crizotinib (CRZ) in Asian versus non-Asian patients (pts) in the phase III ALTA-1L trial." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 9026. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.9026.
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9026 Background: We report an analysis of BRG vs CRZ in Asian vs non-Asian pts with ALK inhibitor–naive, ALK+ NSCLC from ALTA-1L (NCT02737501). Methods: Pts were randomized 1:1 to BRG 180 mg QD (7-day lead-in at 90 mg) or CRZ 250 mg BID. Primary endpoint: blinded independent review committee (BIRC)-assessed PFS (RECIST v1.1). Secondary efficacy endpoints: BIRC-assessed ORR, intracranial (i) ORR, and iPFS. Results: 275 pts were randomized; 108 Asian (BRG/CRZ, n = 59/49), 167 non-Asian (n = 78/89); median age: Asian, 55/56 y; non-Asian, 60/60 y. 32/24% of Asians vs 22/28% of non-Asians received prior chemotherapy for advanced disease; 36/33% vs 24/28% had baseline CNS metastases. As of 19 Feb 2018, median follow-up was 10.1/10.0 mo (BRG/CRZ) in Asians vs 11.0/9.0 mo in non-Asians, with 12 vs 20 PFS events in Asians and 24 vs 43 in non-Asians. In Asians, median BIRC-assessed PFS (mo) was not reached (NR; 95% CI 11.2–NR) with BRG vs 11.1 (9.2–NR) with CRZ (HR 0.41 [95% CI 0.20–0.86]; log-rank P= 0.0261); in non-Asians, BRG PFS was NR (NR) vs 9.4 (7.3–NR) with CRZ (HR 0.54 [0.33–0.90]; log-rank P= 0.0132) (Table). AE profile of each drug was similar in Asians vs non-Asians. Most common any-grade AEs (≥25%) in Asians in BRG arm: diarrhea; elevated blood CPK, ALT, and AST. Discontinuation due to AE (BRG/CRZ): 8.5/6.3% in Asian pts; 14.3/10.1% in non-Asian pts. Conclusions: BRG showed comparable improvement in PFS vs CRZ both in Asians and non-Asians in ALK inhibitor–naive ALK+ NSCLC. Clinical trial information: NCT02737501. [Table: see text]
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Lu, Jackson G., Richard E. Nisbett, and Michael W. Morris. "Why East Asians but not South Asians are underrepresented in leadership positions in the United States." Proceedings of the National Academy of Sciences 117, no. 9 (February 18, 2020): 4590–600. http://dx.doi.org/10.1073/pnas.1918896117.
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Well-educated and prosperous, Asians are called the “model minority” in the United States. However, they appear disproportionately underrepresented in leadership positions, a problem known as the “bamboo ceiling.” It remains unclear why this problem exists and whether it applies to all Asians or only particular Asian subgroups. To investigate the mechanisms and scope of the problem, we compared the leadership attainment of the two largest Asian subgroups in the United States: East Asians (e.g., Chinese) and South Asians (e.g., Indians). Across nine studies (n= 11,030) using mixed methods (archival analyses of chief executive officers, field surveys in large US companies, student leader nominations and elections, and experiments), East Asians were less likely than South Asians and whites to attain leadership positions, whereas South Asians were more likely than whites to do so. To understand why the bamboo ceiling exists for East Asians but not South Asians, we examined three categories of mechanisms—prejudice (intergroup), motivation (intrapersonal), and assertiveness (interpersonal)—while controlling for demographics (e.g., birth country, English fluency, education, socioeconomic status). Analyses revealed that East Asians faced less prejudice than South Asians and were equally motivated by work and leadership as South Asians. However, East Asians were lower in assertiveness, which consistently mediated the leadership attainment gap between East Asians and South Asians. These results suggest that East Asians hit the bamboo ceiling because their low assertiveness is incongruent with American norms concerning how leaders should communicate. The bamboo ceiling is not an Asian issue, but an issue of cultural fit.
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Ly, Luong, Thida Win, Jessica Mantilla, Ching-Hsiu Chiu, Allan Leung, Chia-Hsing Yeh, Wen-Hsiang Teng, et al. "Impact of COVID-19 on hospitalization, death rate, and other inpatient measures among Asian patients in hospitals in California." Journal of Hospital Administration 10, no. 5 (December 13, 2021): 31. http://dx.doi.org/10.5430/jha.v10n5p31.
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Objective: This study aims to analyze COVID-19 hospitalization and death rate in the Asian population of a predominantly Asian-serving multi-hospital system (ASMHS).Methods: The COVID-19 patient information was collected electronically from March 1 to November 12, 2020, including demographics, insurance, mortality, ICU admissions, and length of stay (LOS). Demographic characteristics were compared with the county-level and national data. A comparison of hospital LOS between Asians and non-Asians was conducted.Results: The prevalence ratio of deaths in Asians at ASMHS was 1.29, which was 53% higher than the county and 77% higher than the nation. The ICU admission for ASMHS Asian patients was 11.8% compared to 5.6% for non-Asian. Overall Asians and Asians aged > 65 had significantly longer LOS than non-Asians (p < .001).Conclusions: High prevalence ratio of deaths was noted in ASMHS’s Asian patients which may be related to older age, higher ICU rate, and longer LOS.
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Lee, Stacey J., Choua P. Xiong, Linda M. Pheng, and Mai Neng Vang. "“Asians for Black Lives, Not Asians for Asians”: Building Southeast Asian American and Black Solidarity." Anthropology & Education Quarterly 51, no. 4 (September 15, 2020): 405–21. http://dx.doi.org/10.1111/aeq.12354.
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Misra, Supriya, Laura C. Wyatt, Jennifer A. Wong, Cindy Y. Huang, Shahmir H. Ali, Chau Trinh-Shevrin, Nadia S. Islam, Stella S. Yi, and Simona C. Kwon. "Determinants of Depression Risk among Three Asian American Subgroups in New York City." Ethnicity & Disease 30, no. 4 (September 24, 2020): 553–62. http://dx.doi.org/10.18865/ed.30.4.553.
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Objective: Although the fastest growing minority group, Asian Americans receive little attention in mental health research. Moreover, aggregated data mask further diversity within Asian Americans. This study aimed to examine depression risk by detailed Asian American subgroup, and further assess determinants within and between three Asian ethnic subgroups.Methods: Needs assessment surveys were collected in 16 Asian American subgroups (six Southeast Asian, six South Asian, and four East Asian) in New York City from 2013-2016 using community-based sampling strategies. A final sample of N=1,532 completed the PHQ-2. Bivariate comparisons and multivariable logistic models explored differences in depression risk by subgroup.Results: Southeast Asians had the greatest depression risk (19%), followed by South Asians (11%) and East Asians (9%). Among Southeast Asians, depression risk was associated with lacking health insurance (OR=.2, 95% CI: 0-.6), not having a provider who speaks the same language (OR=3.2, 95% CI: 1.3-8.0), and lower neighborhood social cohesion (OR= .94, 95% CI: .71-.99). Among South Asians, depression risk was associated with greater English proficiency (OR=3.9, 95% CI: 1.6-9.2); and among East Asians, depression risk was associated with ≤ high school education (OR=4.2, 95% CI: 1.2-14.3). Additionally, among Southeast Asians and South Asians, the highest depression risk was associated with high levels of discrimination (Southeast Asian: OR=9.9, 95% CI: 1.8-56.2; South Asian: OR=7.3, 95% CI: 3.3-16.2).Conclusions: Depression risk and determinants differed by Asian American ethnic subgroup. Identifying factors associated with depression risk among these groups is key to targeting limited public health resources for these underserved communities. Ethn Dis. 2020;30(4):553-562; doi:10.18865/ed.30.4.553
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Kim, So Young. "Do Asian Values Exist? Empirical Tests of the Four Dimensions of Asian Values." Journal of East Asian Studies 10, no. 2 (August 2010): 315–44. http://dx.doi.org/10.1017/s1598240800003477.
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The Asian values debate has been long on speculative advocacy but short on empirical validation, with statistical tests emerging only lately. This study explores two questions: whether Asians indeed hold distinct cultural attitudes when compared with non-Asians and whether these cultural attitudes and beliefs identified as Asian values form coherent dimensions among Asians. The study first identifies four dimensions of Asian values based on a review of various Asian values discourses: familism, communalism, authority orientations, and work ethic. The findings from the empirical analysis based on multilevel models and factor analysis return mixed support for the Asian values hypothesis. Although East Asian respondents do exhibit strong work-related values compared with those from other regions, commitment to familial values and authoritarian orientations are actually lower among East Asians. Also, while preference for strong leadership and parental duty do turn out to form distinct sets of attitudes among South and Southeast Asians, the four dimensions do not constitute a clear value complex in the minds of East Asians.
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Wang, Kang-Ling, Gregory Y. H. Lip, and Chern-En Chiang. "Stroke prevention in atrial fibrillation: An Asian perspective." Thrombosis and Haemostasis 111, no. 05 (2014): 789–97. http://dx.doi.org/10.1160/th13-11-0948.
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SummaryAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia. In 2050, it is estimated that there will be 72 million AF patients in Asia, accounting for almost 2.9 million patients suffering from AF-associated stroke. Asian AF patients share similar risk factor profiles as non-Asians, except that more Asians have a history of previous stroke. Clinical challenges are evident in the field of stroke prevention in AF, amongst Asians. Existing stroke and bleeding risk scores have not been well-validated in Asians. Asians are prone to bleeding when treated with warfarin, and the optimal international normalised ratio (INR) for warfarin use is yet to be determined in Asians, though Asian physicians tend to keep it in a lower range (e.g. INR 1.6–2.6) for elderly patients despite limited evidence to justify this. In general, warfarin is ‘difficult’ to use in Asians due to higher risk of bleeding and higher stroke rate in Asians than in non-Asians, as shown in randomised controlled trials. Excess of bleeding was not found in Asians when novel oral anticoagulants (NOACs) were used. Besides, the superiority of NOACs to warfarin in reducing thromboembolism was maintained in Asians. Therefore NOACs are preferentially indicated in Asians in terms of both efficacy and safety. Also, some preliminary data suggest that Asian patients with AF might not be the same. Future prospective randomised trials are needed for the selection of NOACs according to different ethnic background.Note: The review process for this manuscript was fully handled by Christian Weber, Editor in Chief.
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Johnson, Ronald C., and Craig T. Nagoshi. "Asians, Asian-Americans and Alcohol." Journal of Psychoactive Drugs 22, no. 1 (January 1990): 45–52. http://dx.doi.org/10.1080/02791072.1990.10472196.
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Hu, Adriana, Yi-Kong Keung, Ryan A. Lau, Lap-Woon Keung, and Eddie Hu. "Retrospective analysis of breast cancer patients in an Asian-majority community clinic." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): e12502-e12502. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e12502.
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e12502 Background: Incidence of breast cancer in Asian countries is about one third to one half of that of the US. Asian immigrants have a higher risk of developing breast cancer in the US presumably by adopting more westernized lifestyles. We conduct a retrospective analysis of breast cancer patients (pts) in an Asian-majority community in Southern California. Methods: Unselected consecutive female breast cancer pts were studied. Clinical data were review and statistical analysis was conducted by SPSS 16.0. Results: 501 pts, 334 Asians (incl. Chinese 84%) and 167 non-Asians (incl. Caucasian 47% and Hispanic 45%) were studied. Conclusions: This study raised several intriguing findings: 1. Asian pts are significantly younger and have lower BMI than non-Asians. 2. Asian pts are more likely to undergo mastectomy than breast conserving surgery. 3. Asian pts tend to have denser breasts which may potentially limit the sensitivity of mammogram. Since the ratio of DCIS to invasive cancer is comparable between Asian and non-Asian pts in this study, mammogram is probably effective in detecting early cancer in Asians. 4. Significantly fewer Asian pts are diagnosed by screening mammogram. It is probably due to lower utilization of mammogram in the Asian population. 5. BRCA1/2 mutation is not significantly different between Asians and non-Asians. Due to inherent limitations of retrospective study, these findings need to be confirmed in a larger prospective study. [Table: see text]
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Petri, Michelle, Chenglong Fang, and Daniel W. Goldman. "East-Asian lupus nephritis in the Hopkins Lupus Cohort." Rheumatology and Immunology Research 4, no. 3 (September 1, 2023): 157–61. http://dx.doi.org/10.2478/rir-2023-0022.
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Abstract Background and Objective East Asian systemic lupus erythematosus (SLE) is under represented in lupus cohorts outside of East Asia. We asked whether lupus nephritis was more common and more severe in East Asians than in other ethnicities in a large United States SLE cohort. Methods The Hopkins Lupus Cohort, a longitudinal cohort of 2802 patients (53.5% Caucasian, 39.2% African-American, 3.2% East Asian) was studied. The SLICC/ACR Damage Index was used to assess renal outcomes. Results: East Asian patients had the same prevalence of lupus nephritis as African-Americans and both were higher than Caucasians. East Asians were not significantly different in frequency of end stage kidney disease compared with African-Americans. East Asians were more likely than Caucasians to have anti-Sm, low C3 and low C4. East Asians were more likely than African-Americans to have low C3 and low C4. Conclusion East Asians living in the United States were more likely to have lupus nephritis than Caucasians. Poor outcomes such as end stage kidney disease occurred at an equal frequency in East Asians as in African-Americans. Lupus nephritis was both more frequent and more severe in East Asians than in African-Americans.
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Cabrera, Joseph F., and Rachael R. Dela Cruz. "Spatially Based Rules for Reducing Multiple–Race into Single–Race Data." City & Community 19, no. 3 (September 2020): 593–616. http://dx.doi.org/10.1111/cico.12418.
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There is a discord between the categorization of mixed–race data in spatial studies, which has become more complex as the mixed–race population increases. We offer an efficient, spatially based method for assigning mixed–race respondents into single–race categories. The present study examined diversity within 25 Metropolitan Statistical Areas in the United States to develop this racial bridging method. We identify prescriptions for each two–race category based on average diversity experiences and similarity scores derived from census tract data. The results show the following category assignments: (1) Black–Asians to Black, (2) White–others to White, (3) Asian–others to Asian, (4) White–Blacks to other, (5) White–Asians to White (if Asian >3.0 percent), (6) White–Asians to Asian (if Asian <3.0 percent), (7) Black–Asians to other (if Black >8.5 percent), and (8) Black–Asians to Black (if Black <8.5 percent). We argue that the proposed method is appropriate for all race–based studies using spatially relevant theoretical constructs such as segregation and gentrification.
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Aurelius, Taylor, Gie Ken-Dror, Sapna D. Sharma, Sageet Amlani, Gunaratnam Gunathilagan, David L. Cohen, Chakravarthi Rajkumar, et al. "Atrial fibrillation in UK South Asian hospitalized ischemic stroke patients: The BRAINS study." PLOS ONE 18, no. 2 (February 7, 2023): e0281014. http://dx.doi.org/10.1371/journal.pone.0281014.
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Introduction South Asian diaspora comprise one of the largest ethnic minority groups in the world yet data about atrial fibrillation (AF) in this demographic is understudied. Our aim is to identify differences in AF prevalence and treatment between South Asians and white British stroke patients. Method The UK arm of a prospective ongoing large international repository on stroke was analysed. Ethnic differences in AF prevalence and management in those with ischemic stroke were analysed. Results Of the 3515 individuals recruited with ischemic stroke, 1482 (men: 972, women: 510) were South Asian and 2033 (men:1141, women:892) of white British ethnicity. AF was present in 462 white British and 193 South Asians stroke patients, with South Asians displaying a lower prevalence of AF (South Asians: 13.0% vs white British 22.7%, P<0.001). Despite adjustment for traditional AF risk factors, South Asians had a significantly lower OR of AF compared to white British stroke patients (OR: 0.40, 95%CI: 0.33:0.49, P<0.001). Among confirmed AF cases, 31.8% of South Asians and 41.4% of white British were untreated at admission (P = 0.02). Antiplatelet treatment was significantly higher among South Asians at both admission (South Asian: 47.4% vs. white British: 29.9%, P<0.001) and discharge (South Asian: 49.5% vs. white British: 34.7%, P = 0.001), although anticoagulation treatment was similar across both ethnic groups at admission (South Asian: 28.5% vs white British: 28.1%, P = 0.93), and discharge (South Asian: 45.1% vs white British: 43.1%, P = 0.64). Conclusion Stroke patients of South Asian descent are at significantly lower risk of AF but more likely to be on antiplatelet treatment compared to their white British counterparts.
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Wu, Cary. "How Anti-Asian Racism is Experienced." Contexts 21, no. 3 (August 2022): 48–51. http://dx.doi.org/10.1177/15365042221114990.
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Growing attention has been given to the massive spike in anti-Asian hate crimes since the COVID-19 outbreak. But it is also essential to recognize that not all Asians experience the rise of anti-Asian racism to the same degree. Many individual and contextual factors may shape individuals’ subjective experience of anti-Asian racism. Underlying Asians’ differential experiences are the unequal psychological consequences they bear. This essay explores nativity, and co-ethnic concentration, as well as how they interact to affect Asians’ experience of anti-Asian racism.
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Prashad, Vijay. "From Multiculture to Polyculture in South Asian American Studies." Diaspora: A Journal of Transnational Studies 8, no. 2 (September 1999): 185–204. http://dx.doi.org/10.3138/diaspora.8.2.185.
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In 1997, Contours of the Heart: South Asians Map North America won the American Book Award from the Before Columbus Foundation (Maira and Srikanth). This was unexpected, not because of the quality of the book, but principally because of the little attention hitherto given to those who write about the “new immigrants” of the Americas (including South Asians, Filipinos, Southeast Asians, Africans, and West Asians). Prior to 1997, scholars and writers of South Asian America had been known to skulk in the halls of even such marginal events as the Asian American Studies Association and complain about the slight presence of South Asian American panels. That complaint can now be put to rest.
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Im, Seock-Ah, Hirofumi Mukai, In Hae Park, Norikazu Masuda, Chikako Shimizu, Sung-Bae Kim, Young-Hyuck Im, et al. "Palbociclib Plus Letrozole as First-Line Therapy in Postmenopausal Asian Women With Metastatic Breast Cancer: Results From the Phase III, Randomized PALOMA-2 Study." Journal of Global Oncology, no. 5 (December 2019): 1–19. http://dx.doi.org/10.1200/jgo.18.00173.
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PURPOSE In PALOMA-2, palbociclib plus letrozole significantly improved progression-free survival (PFS) as initial treatment of estrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer. We assessed the benefit of palbociclib plus letrozole in Asians. PATIENTS AND METHODS Of 666 enrolled postmenopausal women with estrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer (no prior treatment of advanced disease), 95 were Asian. Patients were randomly assigned 2:1 to receive palbociclib plus letrozole or placebo plus letrozole. The primary end point was investigator-assessed PFS. Secondary end points were overall survival, objective response, patient-reported outcomes, pharmacokinetics, and safety. RESULTS Median PFS was significantly longer in Asian patients who received palbociclib plus letrozole versus placebo plus letrozole (25.7 months [95% CI, 19.2 months to not estimable] v 13.9 months [95% CI, 7.4 to 22.0 months]; hazard ratio, 0.48; 95% CI, 0.27 to 0.87; P = .007). The most common toxicities with palbociclib were hematologic and more frequent among Asians versus non-Asians: neutropenia (any grade, 95.4% v 76.8%; grade 3/4, 89.2% v 62.5%), leukopenia (43.1% v 38.3%; 32.3% v 23.5%), and thrombocytopenia (27.7% v 13.5%; 4.6% v 1.1%). No Asians had febrile neutropenia. Discontinuation rates as a result of adverse events were similar among Asian and non-Asian patients who received palbociclib plus letrozole (10.8% and 9.5%). In Asians, quality of life (QOL) was maintained with no significant differences observed between treatments from baseline in breast cancer–specific QOL and general health status scores. Change from baseline in EuroQol five dimensions index scores was significantly higher with palbociclib plus letrozole (0.013 v –0.069; P = .0132). Geometric mean palbociclib trough concentration values were higher in Asians versus non-Asians (93.8 v 61.7 ng/mL). CONCLUSION Consistent with the overall study population, the addition of palbociclib to letrozole significantly improved PFS in Asians. Hematologic toxicities were more frequent in Asians versus non-Asians but manageable with early dose modifications while maintaining QOL.
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Gama, R., AB Elfatih, and NR Anderson. "Ethnic Differences in Total and HDL Cholesterol Concentrations: Caucasians Compared with Predominantly Punjabi Sikh Indo-Asians." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 39, no. 6 (November 2002): 609–11. http://dx.doi.org/10.1177/000456320203900612.
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Background In comparison with Caucasians, Indo-Asians resident in the UK have similar total cholesterol but lower HDL cholesterol (HDLC) concentrations. It is however possible that cardiovascular risk factors may vary between culturally different Indo-Asians. Methods We present data on 223 Indo-Asians (129 men, 94 women) and 787 Caucasians (421 men, 366 women) in whom a laboratory-based coronary heart disease (CHD) risk score calculation had been requested. Results Total cholesterol concentrations were similar in Indo-Asians and Caucasians. HDLC concentrations were higher ( P< 0·001) in Caucasians [1·4 (1·3–1·4) mmol/L; median (95% confidence intervals)] than in Indo-Asians [1·2 (1·2–1·3) mmol/L]. Indo-Asian women [1·2 (1·2–1·3) mmol/L], Indo-Asian men [1·2 (1·2–1·3) mmol/L] and Caucasian men [1·2 (1·2–1·3) mmol/L] had similar HDLC concentrations but these were all lower ( P< 0·001) than those in Caucasian women [1·4 (1·3–1·4) mmol/L]. Conclusion We confirm low HDLC concentrations in Indo-Asians, but propose that this is solely due to low HDLC concentrations in Indo-Asian women. Since Indo-Asians in Wolverhampton are predominantly Punjabi Sikhs, we suggest that the difference between this study and previous reports may be due to heterogeneity of CHD risk factors within culturally diverse Indo-Asians.
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Sutton, G. C., A. Storer, and K. Rowe. "Cancer screening coverage of south Asian women in Wakefield." Journal of Medical Screening 8, no. 4 (December 1, 2001): 183–86. http://dx.doi.org/10.1136/jms.8.4.183.
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OBJECTIVE:To measure the cervical and breast screening coverage of south Asian women in Wakefield, compared with other city residents. DESIGN:Pairwise measurement of screening histories of women whose names appeared to be south Asian, and of non-Asian women matched by date of birth and general practice. Data source—Computerised records of screening histories held by West Yorkshire Central Services Agency, for the eight general practices in central Wakefield. RESULTS:67% of south Asians and 75% of non-Asians had acceptable (not overdue) cervical screening histories (&khgr;2=13.75, p<0.001). 53% of south Asians and 78% of non-Asians had acceptable breast screening histories (&khgr;2=8.5, p<0.01) CONCLUSION:Interventions should be designed to improve coverage for breast screening among south Asian women. The need for such interventions for cervical screening is equivocal.
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Yoon, Clara Haneul. "Empowering Asian Educators in the Time of Crisis." Action, Criticism, and Theory for Music Education 21, no. 2 (September 2022): 57–88. http://dx.doi.org/10.22176/act21.2.57.
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In this article, I draw from my experience working as a Korean American music teacher in the US. I reflect on what it means to be Asian American and to bring Asian narratives to the forefront. I examine the distinct challenges of social justice in the context of Asians and Asian Americans’ lives—particularly through the lens of the “model minority.” The COVID-19 pandemic has spotlighted Asians and Asian Americans’ lived experiences in ways unlike before. I discuss perceptions of Asians throughout US history and the current representativeness of Asian music in the framework of multicultural education. Grounded in Erving Goffman’s notion of covering, Kenji Yoshino’s extension of this concept (the four axes of covering), and Edward Said’s Orientalism, I make seven recommendations to empower Asians and Asian educators in this time of crisis. The article explores and situates the current challenges of anti-Asian racism, connecting it to aforementioned theories and briefly proposes the concept of 홍익인간 (Hongik-Ingan) to course-correct, support, and acknowledge Asian educators’ multiplicity of identities as allies.
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Gill, Sharlene, Amil Shah, Nhu Le, E. Francis Cook, and Eric M. Yoshida. "Asian Ethnicity–Related Differences in Gastric Cancer Presentation and Outcome Among Patients Treated at a Canadian Cancer Center." Journal of Clinical Oncology 21, no. 11 (June 1, 2003): 2070–76. http://dx.doi.org/10.1200/jco.2003.11.054.
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Purpose: Differences in stage-stratified survival have been reported between Asian and Western populations with gastric cancer. This study examines differences in presentation and outcomes among Asian and non-Asian patients evaluated and treated at a Canadian institution. Patients and Methods: We reviewed 2,043 patients (159 Asians and 1,884 non-Asians) with gastric adenocarcinoma treated between 1978 and 1997. Overall survival was examined by the Kaplan-Meier method, and multivariable analysis by Cox proportional hazards was used to identify whether Asian ethnicity had independent prognostic significance for survival. Results: Median survival was 13.1 months for Asians and 11.1 months for non-Asians (P = .0016). Asian patients were younger and had a greater proportion of signet ring cell histology but were less likely to have proximal disease. Signet ring cell histology did not adversely affect survival. By multivariable analysis, proximal location, poor differentiation, and extent of disease were independently associated with worse survival. Survival was improved with curative resection, palliative resection, and palliative chemotherapy. Asian ethnicity was not independently associated with survival (hazard ratio, 0.89; 95% confidence interval, 0.74 to 1.08). Although a similar proportion of patients underwent curative resection, an interaction was observed between Asian ethnicity and efficacy of resection, with Asians achieving a greater benefit as compared with non-Asians even when adjusted for age and location. Conclusion: The disparity between Eastern and Western gastric cancer survival is not explained by the hypothesis of ethnicity-related differences in tumor biology. Although it is not an independent predictor of survival, Asian ethnicity is associated with distinct characteristics at presentation and more favorable outcomes after curative surgery.
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Li, Wenjun, and Su-I. Hou. "AAA Research Methodology I: Overcoming Linguistic and Cultural Barriers in Aging Research Among Asians." Innovation in Aging 4, Supplement_1 (December 1, 2020): 812. http://dx.doi.org/10.1093/geroni/igaa057.2952.
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Abstract Asians are the largest and the fastest growing segment of the world population. Asian immigrants are the second largest immigrant population in the U.S. However, their age-related social and health issues are understudied. Because studies on older Asians are often scattered geographically and small-sized and study instruments are usually inconsistent in context, language and culture, it is difficult to synthesize findings from different studies on Asians. Little data exist to support health promotion, policy evaluation and clinical practice in this population. To advance research into aging among Asians, a fundamental step is to create content-relevant, linguistically and culturally appropriate research instruments, and encourage use of these consistent and comparable instruments across studies. This symposium brings together four abstracts that report the development and adaptation of linguistically and culturally appropriate survey instruments for health and behavioral studies in older Asians. The topics range from development of new scales for generative concern and acts in older Singaporeans, assessment of appropriateness of health literacy measurements among East Asian older adults, validation of Health Aging Instrument in Southeastern Asian older adults. Based on the experiences in these studies, the group will discuss the need and strategies to develop an international network to promote resource sharing and research collaborations across geographic boundaries and disciplinary divisions. By bringing together the isolated but talented Asian health researchers, the new network may accelerate the growth of research on Aging Among Asians. This symposium is a collaborative effort of the Aging Among Asians Interest Group.
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Nugraheni, Priskilla Trisna, Michael Bezaleel Wenas, and Birmanti Setya Utami. "A SEMIOTIC ANALYSIS OF ASIAN WOMEN’S STEREOTYPES ON CHO CHANG." Capture : Jurnal Seni Media Rekam 14, no. 2 (July 4, 2023): 136–53. http://dx.doi.org/10.33153/capture.v14i2.5019.
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Stereotypes against Asians emerge and develop as a form of propaganda for Americans. Cho Chang, a character from the Harry Potter film series, exemplifies negative stereotypes of Asian women. Accordingly, this study aims to identify which stereotypes of Asian women correspond to the existing reality. Using Barthes’ semiotic theory, this study employed qualitative analysis. The findings indicate stereotypes that fit the audience’s interpretation, i.e., Asian women are exotic and charming, Asians are academically intelligent, and Asian women easily change their partners. Meanwhile, stereotypes that do not fit with the audience’s interpretations include: Asians are clumsy, weird, and disliked by Americans, and the “Dragon Lady” image of Asian women who is cunning, sadistic, and untrustworthy.
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Caboral-Stevens, Meriam, Alice Jo Rainville, Olivia Ford, Xining Yang, Jessica Donnelly, Rachel Bessire, Tameka Jackson-Dyer, John Sonnega, and Tsu-Yin Wu. "Challenges and Successes in Health Communication Messaging With Asian Americans." Health Promotion Practice 23, no. 1_suppl (November 2022): 149S—152S. http://dx.doi.org/10.1177/15248399221115449.
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Asians are the fastest growing racial and ethnic group in the United States, and in Michigan, Asians represent 3.4% of the state’s population. Asians have long been aggregated as a homogeneous group and stereotyped as a “model minority.” Asians, however, are very diverse, and each subgroup has different values, histories, beliefs, and dialects. The diversity among populations and variations in chronic disease risks demonstrate the importance of disaggregating Asian American ethnicities with respect to health promotion, which must be culturally and linguistically tailored to make the biggest impact. This article describes our challenges and successes in health communication messaging with Asian Americans during the 4 years of our Racial and Ethnic Approaches to Community Health (REACH) Cooperative Agreement.
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Chang, Elaine, Yutao Gong, Jonathon Joseph Vallejo, QI LIU, Luckson Noe Mathieu, Brian Booth, Rajeshwari Sridhara, Julia A. Beaver, Richard Pazdur, and Gideon Michael Blumenthal. "FDA analysis of outcomes in Asian patients (pts) with metastatic non-small cell lung cancer (mNSCLC) receiving immune checkpoint inhibitors (ICI)." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e20690-e20690. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e20690.
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e20690 Background: Asian pts tend to be well-represented in mNSCLC clinical trials, and drug development in Asia is growing. We sought to investigate outcomes of Asian pts enrolled in clinical trials testing ICI in mNSCLC. Methods: We identified 11 ICI mNSCLC randomized trials submitted to FDA 2014-2018. We divided the trials into 3 groups: 1st-line monotherapy (1L-M), 1st-line combination with chemotherapy [chemo] (1L-C), and 2nd-line monotherapy (2L-M). Overall survival (OS) and progression-free survival (PFS) were evaluated with Kaplan-Meier methodology. We performed meta-analyses to assess if treatment effect is consistent across Asian and non-Asian populations. Results: There were 3399 patients enrolled in five 2L-M trials, 1579 in two 1L-M trials, and 2500 in four 1L-C trials. Most Asian pts were located geographically in Asia (90%). Asians comprised 15% of patients enrolled in 2L-M trials, 27% in 1L-M, and 11% in 1L-C. Compared to non-Asians, a higher proportion of Asians were never-smokers (32% vs. 13%) and EGFR-mutated (13% vs. 4%). Asian pts had better unadjusted and adjusted OS than non-Asian pts for each treatment in each line of therapy. The 3 covariates with greatest prognostic impact on OS in 2L-M were race, performance status, and histology. The magnitude of ICI treatment effect relative to chemo was similar for Asian and non-Asian pts. Conclusions: Asians appear to have better prognosis than non-Asians; no uniquely better or worse benefit was observed from ICI when compared to chemotherapy. [Table: see text]
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Cheng, Stephen K. K. "Understanding the Culture and Behaviour of East Asians — A Confucian Perspective." Australian & New Zealand Journal of Psychiatry 24, no. 4 (December 1990): 510–15. http://dx.doi.org/10.3109/00048679009062907.
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The economic miracle of East Asia is followed by the emergence of a new common identity in Confucianism among the nations in the region. Being the predominant cultural determining force in East Asia, Confucianism has deeply influenced East Asian behaviour. Three behavioural traits in East Asians are discussed. First, the East Asian's lack of “personality” is traced to the Confucian social institution of Li — rules of propriety. Second, the East Asian's lack of principled moral thinking is linked to the dyadic, relation-based character of the Confucian ethic, its lack of hypothetical reasoning and its hierarchical view of human relationships. Third, the East Asian's lack of assertiveness is rooted in the Confucian ideal of man as a reflection of harmony in the cosmos and the Confucian ideal of society as based on the fulfilment of duties rather than the assertion of rights. The implications of these Confucian traits suggest the need to re-formulate Western conceptions of and approaches to East Asian behaviour.
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WING, Clive D. "Do Asians value Asian information? —Revisted—." Journal of Information Processing and Management 46, no. 5 (2003): 326–28. http://dx.doi.org/10.1241/johokanri.46.326.
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Karipineni, Farah, Afshin Parsikia, PoNan Chang, John Pang, Stalin Campos, Kamran Khanmoradi, Radi Zaki, and Jorge Ortiz. "Dispelling the myth of Asian homogeneity: Improved outcomes of Chinese Americans after kidney transplantation." Translation: The University of Toledo Journal of Medical Sciences 3 (June 27, 2018): 5–9. http://dx.doi.org/10.46570/utjms.vol3-2016-201.
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Objectives: Asians represent the fastest growing ethnic group in the United States. Despite significant diversity within the group, many transplant studies treat Asians as a homogeneous entity. We compared patient and graft survival among major Asian eth- nicities to determine whether any subgroup has superior out- comes. Methods: We conducted a retrospective analysis of kidney trans- plants on Asian and White patients between 2001 and 2012. Co- variates included gender, age, comorbidities, and donor category. Primary outcomes included one-year patient and graft survival. Secondary outcomes included delayed graft function (DGF) and rejection as cause of graft loss and death. Results: Ninety-one Asian patients were identified. Due to the large proportion of Chinese patients (n=37), we grouped other Asians into one entity (n=54) for statistical comparison among Chinese, other Asians, and Whites (n=346). Chinese subjects had significantly lower body mass index (BMI) (p=0.001) and had the lowest proportion of living donors (p>0.001). Patient survival was highest in our Chinese cohort (p>0.001)Discussion: Our study confirms outcome differences among Asian subgroups in kidney transplantation. Chinese demonstrate better patient survival at one year than Whites and non-Chinese Asians despite fewer live donors. Lower BMI scores may partly explain this. Larger, long-term studies are needed to elucidate outcome disparities among Asian subgroups
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Karipineni, Farah, Afshin Parsikia, PoNan Chang, John Pang, Stalin Campos, Kamran Khanmoradi, Radi Zaki, and Jorge Ortiz. "Dispelling the myth of Asian homogeneity: Improved outcomes of Chinese Americans after kidney transplantation." Translation: The University of Toledo Journal of Medical Sciences 10, no. 1 (December 20, 2022): 5–9. http://dx.doi.org/10.46570/utjms.vol10-2016-201.
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Objectives: Asians represent the fastest growing ethnic group in the United States. Despite significant diversity within the group, many transplant studies treat Asians as a homogeneous entity. We compared patient and graft survival among major Asian eth- nicities to determine whether any subgroup has superior out- comes. Methods: We conducted a retrospective analysis of kidney trans- plants on Asian and White patients between 2001 and 2012. Co- variates included gender, age, comorbidities, and donor category. Primary outcomes included one-year patient and graft survival. Secondary outcomes included delayed graft function (DGF) and rejection as cause of graft loss and death. Results: Ninety-one Asian patients were identified. Due to the large proportion of Chinese patients (n=37), we grouped other Asians into one entity (n=54) for statistical comparison among Chinese, other Asians, and Whites (n=346). Chinese subjects had significantly lower body mass index (BMI) (p=0.001) and had the lowest proportion of living donors (p>0.001). Patient survival was highest in our Chinese cohort (p>0.001)Discussion: Our study confirms outcome differences among Asian subgroups in kidney transplantation. Chinese demonstrate better patient survival at one year than Whites and non-Chinese Asians despite fewer live donors. Lower BMI scores may partly explain this. Larger, long-term studies are needed to elucidate outcome disparities among Asian subgroups
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Wu, Tsu-Yin, Olivia Ford, Alice Jo Rainville, Xining Yang, Chong Man Chow, Sarah Lally, Rachel Bessire, and Jessica Donnelly. "Perceptions of COVID-19 Vaccine, Racism, and Social Vulnerability: An Examination among East Asian Americans, Southeast Asian Americans, South Asian Americans, and Others." Vaccines 10, no. 8 (August 17, 2022): 1333. http://dx.doi.org/10.3390/vaccines10081333.
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As COVID-19 vaccines are readily available and most U.S. adults who are enthusiastic about the vaccine have received it, motivating those who have not been vaccinated to accept it has become a challenge. The purpose of this study was to understand the mechanisms behind COVID-19 vaccine acceptance in Asian American ethnic groups, including how sociodemographic characteristics and racism predict COVID-19 and vaccine perceptions. The study also examined associations between social vulnerability and COVID-19 and vaccine perceptions. Social vulnerability is defined as the degree to which a community is able to prepare and respond to a natural or man-made disaster. This cross-sectional study used community-based survey data collected from April to September 2021. Study measures included demographics, perceptions of COVID-19 and COVID-19 vaccines, and racism-related experiences. The results showed that, compared to Non-Asians, East Asians reported that they had significantly more challenges accessing COVID-19 vaccines, and South Asians reported significantly higher safety concerns about COVID-19 vaccines. Our study also found that racism experience mediates the association between race/ethnicity and safety concerns about COVID-19 vaccines. Three Asian subgroups (East Asians, South Asians, and Southeast Asians) experienced more racism (compared to Non-Asians), and more experience of racism was related to greater safety concerns. Geographical Information System (GIS) maps revealed that residents of lower social vulnerability index (SVI) areas reported fewer unfairness perceptions and that higher SVI areas had lower vaccine accessibility and trust in public health agencies. Our study advances the understanding of racism, social vulnerability, and COVID-19 vaccine-related perceptions among Asian Americans. The findings have implications for policymakers and community leaders with respect to tailoring COVID-19 program efforts for socially vulnerable populations and Asian American groups that experience greater challenges regarding vaccine safety concerns and accessibility.
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Fashoyin-Aje, Lola A., Laura L. Fernandes, Steven Lemery, Patricia Keegan, Rajeshwari Sridhara, Jonca C. Bull, and Richard Pazdur. "Asian representation in clinical trials of new drugs for the treatment of cancer." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): 6564. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.6564.
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6564 Background: In the US, statistics for Asians are often aggregated with other racial groups. This poses challenges in estimating the cancer burden and in defining cancer clinical trial enrollment targets in this demographic subgroup. ‘Asian‘ refers to persons with origins in the Far East, Southeast Asia, or the Indian sub-continent. Asians comprise 6% of the US population and the largest Asian subgroups in the US are of Chinese (22%), Filipino (19%), Asian Indian (19%), Vietnamese (10%), Korean (9%), and Japanese (7%) descent. The representation of Asian patients in global clinical trials may not be reflective of the Asian subgroups in the US. FDA conducted an analysis to describe patients categorized as ‘Asian’ in clinical trials supporting the approval of new drugs. Methods: We reviewed the marketing applications of 33 new molecular entities approved for the treatment of solid tumor malignancies between 2011- 2016 to identify trials that provided the primary evidence of safety and efficacy. Results: A total of 29,941 patients were enrolled; 17 % were Asian. Most Asian patients were enrolled in Korea (20%), Taiwan (20%), mainland China (20%), Japan (16%), and US (5%). Few patients were enrolled in India (3%); the Philippines (1%); Vietnam (0). In the US, Asian patients comprised 3% of the total number of patients enrolled. Conclusions: Asian patients represented a heterogeneous mix. A large proportion was enrolled in Taiwan (20%) and Korea (20%), whereas the largest proportion of US Asians have origins in mainland China (22%), the Philippines (19%), India (19%), and Vietnam (10%). Nevertheless, although Asians share a common ancestry, it is not clear whether data from global clinical trials are generalizable to Asian patients in the US. Therefore, strategies to improve the enrollment of US Asian patients in clinical trials are needed. Among patients enrolled in the US, 3% were Asians, a proportion that is below US Asian population estimates (6%). While most site-specific cancer incidence and death rates are lower in US Asians compared to Whites, the rates of some cancers (e. g., stomach and liver) are higher in this group. Therefore, studies are needed to determine adequate enrollment targets in this demographic subgroup.
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Yeo, Pei Ming, Ziying Vanessa Lim, Wei Ding Virlynn Tan, Xiahong Zhao, Hui Yi Chia, Suat Hoon Tan, Melissa Ching Ching Teo, and Melissa Wee Ping Tan. "Melanoma in Singapore: A 20-year review of disease and treatment outcomes." Annals of the Academy of Medicine, Singapore 50, no. 6 (June 30, 2021): 456–66. http://dx.doi.org/10.47102/annals-acadmedsg.2020535.
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Introduction: Melanomas in Asians have different clinicopathological characteristics and prognosis from melanomas in Caucasians. This study reviewed the epidemiology and treatment outcomes of cutaneous melanoma diagnosed at a tertiary referral dermatology centre in Singapore, which has a multiracial population. The study also determined whether Asians had comparable relapse-free and overall survival periods to Caucasians in Singapore. Method: This is a retrospective review of cutaneous melanoma cases in our centre between 1996 and 2015. Results: Sixty-two cases of melanoma were diagnosed in 61 patients: 72.6% occurred in Chinese, 19.4% in Caucasians and 3.2% in Indians, with an over-representation of Caucasians. Superficial spreading melanoma, acral lentiginous melanoma and nodular melanoma comprised 37.1%, 35.5% and 22.6% of the cases, respectively. The median time interval to diagnosis was longer in Asians than Caucasians; median Breslow’s thickness in Asians were significantly thicker than in Caucasians (2.6mm versus 0.9mm, P=0.018) and Asians tend to present at a later stage. The mortality rates for Asians and Caucasians were 52% and 0%, respectively. Conclusion: More physician and patient education on skin cancer awareness is needed in our Asian-predominant population for better outcomes. Keywords: Asian, melanoma, nails, skin neoplasm, survival
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Gardner, Robert W. "Asian Immigration: The View from the United States." Asian and Pacific Migration Journal 1, no. 1 (March 1992): 64–99. http://dx.doi.org/10.1177/011719689200100104.
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Between the 1965 immigration law and 1990, Asian immigration to the United States increased tenfold to a quarter of a million annually. As sender of the most immigrants, Japan has yielded to the Philippines, South Korea, Vietnam, India, and China. From 1974–1989, over 900,000 Southeast Asian refugees entered the United States. Most Asians today are admitted in the family preference category. On average, the sex ratio is balanced, but over 55% of immigrants from South Korea, the Philippines, and Taiwan are female. Asians are occupationally diverse, with a greater number of professionals/executives (35%) than laborers (14%). Though relatively few in number, Asians concentrate geographically (notably in California) and exert growing political influence in those areas. Except for refugees, Asians are generally viewed as having a positive impact as students and workers. On the other hand, inas much as they contribute to ethnic diversity, they fan the current fears over threats to a common American cultural heritage. Anti-Asian hate crimes and interethnic violence have risen. Asian immigration is likely to continue to rise and show greater emphasis on employment preference categories.
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Guo, Yanfang, Rong Luo, Daniel J. Corsi, Ravi Retnakaran, Mark C. Walker, and Shi Wu Wen. "Caucasian and Asian difference in role of type 1 diabetes on large-for-gestational-age neonates." BMJ Open Diabetes Research & Care 8, no. 2 (November 2020): e001746. http://dx.doi.org/10.1136/bmjdrc-2020-001746.
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IntroductionRacial differences in the association between type 1 diabetes mellitus (T1DM) and large-for-gestational-age (LGA) neonates remain unclear. The objective of this study was to compare the effect of T1DM on LGA neonates between Caucasian and Asian women.Research design and methodsA population-based retrospective cohort study was conducted among Caucasian and Asian women who had prenatal screening and gave a singleton live birth in an Ontario hospital between April 2015 and March 2018. Multivariable log-binomial regression models were used to estimate the adjusted relative risks (aRRs) and 95% CIs of T1DM on LGA for Caucasian and Asian women. Relative contribution of T1DM to LGA was examined by multivariable logistic regression model, stratified by Caucasian and Asian women.ResultsA total of 232 503 women (69.4% Caucasians and 30.6% Asians) were included in the final analysis. The rate of T1DM was higher in Caucasians (0.5%) than in Asians (0.2%), and the rate of LGA neonates was also higher in Caucasians (11.0%) than in Asians (5.0%). The association between T1DM and LGA in Caucasians (aRR 4.18, 95% CI (3.84 to 4.55)) was more robust than that in Asians (aRR 2.11, 95% CI (1.24 to 3.59)). T1DM was the fourth strongest contributor to LGA in Caucasians, while T1DM was the seventh contributor to LGA in Asians.ConclusionsT1DM plays a more substantial role in LGA among Caucasians than Asians. Clinicians should be aware of the Caucasian–Asian differences of effects of T1DM on LGA when developing pregnancy management strategies.
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Lu, Yao, Neeraj Kaushal, Xiaoning Huang, and S. Michael Gaddis. "Priming COVID-19 salience increases prejudice and discriminatory intent against Asians and Hispanics." Proceedings of the National Academy of Sciences 118, no. 36 (August 30, 2021): e2105125118. http://dx.doi.org/10.1073/pnas.2105125118.
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Mounting reports in the media suggest that the COVID-19 pandemic has intensified prejudice and discrimination against racial/ethnic minorities, especially Asians. Existing research has focused on discrimination against Asians and is primarily based on self-reported incidents or nonrepresentative samples. We investigate the extent to which COVID-19 has fueled prejudice and discrimination against multiple racial/ethnic minority groups in the United States by examining nationally representative survey data with an embedded vignette experiment about roommate selection (collected in August 2020; n = 5,000). We find that priming COVID-19 salience has an immediate, statistically significant impact: compared to the control group, respondents in the treatment group exhibited increased prejudice and discriminatory intent against East Asian, South Asian, and Hispanic hypothetical room-seekers. The treatment effect is more pronounced in increasing extreme negative attitudes toward the three minority groups than decreasing extreme positive attitudes toward them. This is partly due to the treatment increasing the proportion of respondents who perceive these minority groups as extremely culturally incompatible (Asians and Hispanics) and extremely irresponsible (Asians). Sociopolitical factors did not moderate the treatment effects on attitudes toward Asians, but prior social contact with Hispanics mitigated prejudices against them. These findings suggest that COVID-19–fueled prejudice and discrimination have not been limited to East Asians but are part of a broader phenomenon that has affected Asians generally and Hispanics as well.
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Yang, Philip, and Maggie Bohm-Jordan. "Patterns of Interracial and Interethnic Marriages among Foreign-Born Asians in the United States." Societies 8, no. 3 (September 16, 2018): 87. http://dx.doi.org/10.3390/soc8030087.
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This study examines the patterns of interracial marriage and interethnic marriage among foreign-born Asians in the United States, using pooled data from the 2008–2012 American Community Surveys. Results show that the most dominant pattern of marriage among foreign-born Asians was still intra-ethnic marriage and that interracial marriage, especially with whites, rather than interethnic marriage among Asians, remained the dominant pattern of intermarriages. Out of all foreign-born Asian marriages, inter-Asian marriages stayed at only about 3%. Among all foreign-born Asian groups, Japanese were most likely to marry interracially and interethnically, while Asian Indians had the lowest rates of interracial marriage and interethnic marriage. Foreign-born Asian women were more likely to interracially marry, especially with whites, than foreign-born Asian men, but they were not much different from foreign-born Asian men in terms of their interethnic marriage rate. The findings have significant implications for intermarriage research, assimilation, and Asian American panethnicity.
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Li, Wenjun, Shantha Balaswamy, and Allen Glicksman. "INTEREST GROUP SESSION—AGING AMONG ASIANS: RESEARCH METHODS IN AGING AMONG ASIANS." Innovation in Aging 3, Supplement_1 (November 2019): S364. http://dx.doi.org/10.1093/geroni/igz038.1329.
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Abstract Asians are the largest and the fastest growing segment of the world population. Asian immigrants are the second largest immigrant population in the U.S. However, age-related social and health issues are understudied among late-life immigrant and the oldest old Asians. Little data exist to support public health promotion, policy studies and clinical practice in this population. To advance research into aging among Asians living in the U.S. and elsewhere in the world, sound methodologies can be adopted from those well-developed in other settings while novel methodologies are to be developed to meet the unique needs of Asian studies. This symposium brings together four abstracts that address a variety of common methodological issues in social and health studies among Asian older adults. The topics range from culturally and linguistically appropriate strategies for recruiting non-English speaking research participants, assessment of social isolation and transportation barriers using an ethnographical approach, development of a new culturally appropriate measure for successful aging among the oldest old Chinese in China, and evaluation of preventive healthcare use among faith-based first-generation Chinese immigrants using self-administered surveys in the U.S. These studies involve qualitative ethnographical analysis, mixed methods for instrument development, quantitative data analysis, use of geographic information systems and demography to plan participant recruitment, and use of staged community engagement to increase efficiency and representativeness of participant recruitment. Lessons learned from these studies are valuable to future studies on aging among Asians. This symposium is a collaborative effort of the GSA Aging Among Asians Interest Group.
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Song, Suzan J., Robert Ziegler, Lisa Arsenault, Lise E. Fried, and Karen Hacker. "Asian Student Depression in American High Schools." Journal of School Nursing 27, no. 6 (August 15, 2011): 455–62. http://dx.doi.org/10.1177/1059840511418670.
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There are inconsistent findings about depression in Asians. This study examined risk factors for depression in Asian and Caucasian adolescents. Stratified bivariate secondary analyses of risk indicators and depressed mood were performed in this cross-sectional study of high school survey data (9th to 12th grades) from 2,542 students (198 Asian). Asians had a higher prevalence of depressed symptoms, but similar risk factors as Caucasians. Smoking and injury at work were major risk factors for depressed mood among Asians. Asian-specific risk factors for depression were being foreign-born and having a work-related injury. Asian and Caucasian teens have similar risk factors for depressed mood, though being foreign born and having a work-related injury are risk factors specific to Asian youth, possibly related to social–economic status. Providers of care in school, such as school nurses, can be important primary screeners of depression for Asian students in particular.
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Kurian, A. W., N. M. Chun, M. A. Mills, A. D. Staton, B. A. Crawford, Y. Ridge, S. S. Donlon, G. D. Gong, D. W. West, and J. M. Ford. "BRCA1/2 mutations and cancer risk in Asian-Americans." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 10512. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.10512.
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10512 Background: There are significant differences in breast cancer epidemiology between Caucasian and Asian-Americans and even between different Asian groups. These cancer risks and associated BRCA1/2 mutation prevalence have not been well defined in Asians; BRCA1/2 mutation penetrance might differ due to different risk modifiers. We report on a case-control study of BRCA1/2 mutation prevalence and cancer risk in Asian-American women. Methods: Clinical Data Collection: Chart review from cancer genetics services of 4 North American centers with highest Asian volume. BRCA1/2 Mutation Risk Assessment: BRCAPRO and Myriad II models, CancerGene version 4.3 (University of Texas). BRCA1/2 Mutation Testing: Full sequencing and large rearrangement panel (Myriad Genetics Inc.). Endpoints: BRCA1/2 mutation prevalence and predictive model accuracy (observed versus predicted mutations). Results: 43 of 181 Asians (23.8%) had a BRCA1/2 mutation; 36 (19.9%) had a variant of uncertain significance. The observed prevalence of BRCA1/2 mutations was 23.8% of women, which differs significantly from the predicted prevalence of 12.9% using BRCAPRO (p = 5.6 × 10-9), and the predicted prevalence of 12.6% using Myriad II. This 2-fold difference existed for Chinese, Japanese, and Filipina women (the ethnic sub-groups with enough cases available for comparisons), even though the percent with observed and predicted mutations varied for these three groups. Conclusions: One in 4 clinically tested Asian-Americans has a BRCA1/2 mutation. Standard models significantly under-predict mutations in Asians; consequently, Asians are likely under-tested for BRCA1/2 mutations. These results may reflect lower BRCA1/2-associated cancer risk in Asians compared to Caucasians. Comparison to Caucasian controls and to Asians in Hong Kong is underway, to investigate potential genetic and lifestyle modifiers of BRCA1/2-associated cancer risk. [Table: see text] No significant financial relationships to disclose.
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Wang, Yexin, Gongwei Jia, Jin Song, Xiangqing Kong, Weihong Zhang, and Chunyang Meng. "Comparative Efficacy of Alendronate upon Vertebral Bone Mineral Density and Fracture Rates in East Asians Versus Non-East Asians with Postmenopausal Osteoporosis: A Systematic Review and Meta-Analysis." Hormone and Metabolic Research 50, no. 10 (October 2018): 738–46. http://dx.doi.org/10.1055/a-0741-8300.
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AbstractBisphosphonates, such as alendronate, have become the most widely used and effective anti-resorptive therapy for postmenopausal osteoporosis. Previous genetic studies suggest that ethnicity may drive differing responses to bisphosphonate therapy in East Asians and non-East Asians. Therefore, the aim of this study was to comparatively evaluate the efficacy of alendronate upon lumbar spinal BMD and vertebral fracture rates in East Asians and non-East Asians with postmenopausal osteoporosis. MEDLINE, EMBASE, and Cochrane CENTRAL were searched for relevant randomized controlled trials (RCTs) comparing the efficacy of alendronate versus placebo (or calcium/mineral and/or Vitamin D or hormone replacement therapy) in primary postmenopausal osteoporotic women. We calculated the weighted mean differences (WMDs) for lumbar spinal BMD and the risk ratios (RRs) for vertebral fracture risk along with their respective 95% confidence intervals (CIs). From an initial set of 445 non-duplicate records, 13 full-text articles were finally included in this meta-analysis consisting of four East Asian RCTs and nine non-East Asian RCTs. Alendronate therapy displayed significant effects in improving lumbar spinal BMD in both East Asians [WMD (95% CI)=5.30 (0.32–10.29), p=0.037] and non-East Asians [WMD (95% CI)=5.73 (3.61–7.85), p=0.000]. Alendronate therapy did not display significant effects upon vertebral fracture risk in East Asians [RR (95% CI)=0.41 (0.06–2.73), p=0.358] but did display a significant effect upon lowering vertebral fracture risk in non-East Asians [RR (95% CI)=0.55 (0.42–0.72), p=0.000]. These findings suggest that ethnicity may affect the efficacy of bisphosphonate therapy in postmenopausal osteoporotic women.
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Choi, Sunha. "Sub-Ethnic and Geographic Variations in Out-of-Pocket Private Health Insurance Premiums Among Mid-Life Asians." Journal of Aging and Health 29, no. 2 (July 8, 2016): 222–46. http://dx.doi.org/10.1177/0898264316635563.
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Objective: This study examined out-of-pocket premium burden of mid-life Asian Americans by comparing six sub-groups of Asians after controlling for geographic clustering at the county and state levels. Method: The 2007-2011 National Health Interview Survey was linked to community-level data and analyzed for 4,628 Asians (ages 50-64), including 697 Asian Indians, 1,125 Chinese, 1,393 Filipinos, 434 Japanese, 524 Koreans, and 455 Vietnamese. Non-Hispanic Whites were included as a comparison group ( n = 48,135). Three-level multilevel modeling (state > county > individual) was conducted. Results: Koreans and Vietnamese were found as vulnerable sub-groups considering their lower private health insurance rates and higher uninsured rates. Among those with private insurance, Asians, specifically Filipinos, paid significantly less than non-Hispanic Whites. Moderate but significant variations in the county- and state-level variance in out-of-pocket premiums were found, especially among mid-life Asians. Discussion: This study demonstrates the importance of examining within-group heterogeneity and geographic variations in understanding premium burden among mid-life Asians.
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SHAMS, MANFUSA, and RORY WILLIAMS. "GENERATIONAL CHANGES IN HEIGHT AND BODY MASS DIFFERENCES BETWEEN BRITISH ASIANS AND THE GENERAL POPULATION IN GLASGOW." Journal of Biosocial Science 29, no. 1 (January 1997): 101–9. http://dx.doi.org/10.1017/s0021932097001016.
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A weighted total of 630 pupils aged 14–15 in Glasgow schools, about evenly divided between pupils of South Asian and non-Asian (overwhelmingly British) background, were measured for height and weight and compared with previous results for a similar Glasgow sample aged 30–40. Among 14–15-year-olds, British Asians were not so short compared with non-Asians as among 30–40-year-olds, especially females. Among 30–40-year-old Glasgow Asians only 7% were born in the UK, while among 14–15-year-old Glasgow Asians 86% were so born, indicating that they are the children of migrants. Generational differences in these comparisons cannot be due to positive selection of the migrant generation for height, and are attributed to improved environment, including nutrition and public health measures. This suggests the possibility of corresponding improvements in coronary and diabetic risk.
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McEligot, Archana, Bill Beam, Elizabeth Marquez, and Sinjini Mitra. "Obesity, Fitness and Other Risk Factors in Pacific Islanders Compared with Asian Young Adults." Current Developments in Nutrition 6, Supplement_1 (June 2022): 1075. http://dx.doi.org/10.1093/cdn/nzac070.034.
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Abstract Objectives Obesity, fitness and other risk factor data for Native Hawaiians and Other Pacific Islanders (NHOPI) are frequently aggregated with Asians, who comprise the largest proportion of the Asian and Pacific Islanders (API) race/ethnic category. However, NHOPI compared with Asians are more at-risk and have higher obesity-related morbidity and mortality outcomes. Aggregated data may not provide accurate NHOPI health outcomes data. Therefore, our objective was to measure differences between fitness, obesity and other risk factors in Pacific Islanders (PIs) compared with Asian young adults. Methods Participants completed fitness and obesity assessments, and a health questionnaire from 2006–2015 at a university in Southern California. Participants who self-identified as PIs (n = 191) and Asians (n = 769) were included in the analysis. Independent sample t-tests were conducted to examine differences between PIs and Asians for descriptive statistics, blood pressure, smoking, family history of coronary heart disease (CHD), as well as fitness parameters, including % (%) body fat, relative VO2 max, strength grip, body mass index (BMI) and overall total fitness score (FS). Multiple linear regression was used to investigate the relationship between race/ethnicity (PI vs. Asians) and obesity (dependent variable), adjusting for age, gender, and total FS score. Results Pacific Islander young adults showed significantly higher BMI (23.55 ± 4.06 vs. 22.89 ± 3.83; p = 0.035), % body fat (20.12 ± 7.23 vs. 18.80 ± 7.49; p = 0.029), and higher family history of CHD (p = 0.007) compared to Asians. When controlling for age, gender, and total FS score, significant (p = 0.035) differences in BMI between PIs and Asian young adults persisted. In addition, when comparing BMI by total FS score, PI young adults had significantly higher BMI compared with Asians for only moderate FS scores. Conclusions Even at a young age, we observed increased BMI, % body fat and CHD family history for PIs compared with Asians. Obesity differences persisted despite controlling for age, sex and total FS. The findings support the disaggregation of PI and Asian health data, specifically to hone/tailor obesity prevention and physical activity programs in the NHOPI as early as in college-aged populations. Funding Sources NIH.
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Faroqi-Shah, Yasmeen. "Linguistic and Sociocultural Diversity Among South Asians." Perspectives on Communication Disorders and Sciences in Culturally and Linguistically Diverse (CLD) Populations 19, no. 1 (March 2012): 6–11. http://dx.doi.org/10.1044/cds19.1.6.
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The aim of this paper is to provide information about the ethnocultural and linguistic characteristics of South Asians, because South Asians are one of the most rapidly growing groups in North America. This paper overviews demographic and immigration history and describes sociocultural characteristics and major languages used by speakers of South Asian origin, including dialectal differences in English. I emphasize that, although there are overarching sociocultural similarities among South Asians in terms of family structure and values, there is also considerable heterogeneity depending on specific subgroups, time since migration, and extent of acculturation. Finally, I present guidelines for clinicians who may make service delivery decisions about their South Asian clients.
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Mo, Zongchao, Junyi Xin, Ruichao Chai, Peter Y. M. Woo, Danny T. M. Chan, and Jiguang Wang. "Epidemiological characteristics and genetic alterations in adult diffuse glioma in East Asian populations." Cancer Biology & Medicine 19, no. 10 (November 1, 2022): 1440–59. http://dx.doi.org/10.20892/j.issn.2095-3941.2022.0418.
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Understanding the racial specificities of diseases—such as adult diffuse glioma, the most common primary malignant tumor of the central nervous system—is a critical step toward precision medicine. Here, we comprehensively review studies of gliomas in East Asian populations and other ancestry groups to clarify the racial differences in terms of epidemiology and genomic characteristics. Overall, we observed a lower glioma incidence in East Asians than in Whites; notably, patients with glioblastoma had significantly younger ages of onset and longer overall survival than the Whites. Multiple genome-wide association studies of various cohorts have revealed single nucleotide polymorphisms associated with overall and subtype-specific glioma susceptibility. Notably, only 3 risk loci—5p15.33, 11q23.3, and 20q13.33—were shared between patients with East Asian and White ancestry, whereas other loci predominated only in particular populations. For instance, risk loci 12p11.23, 15q15-21.1, and 19p13.12 were reported in East Asians, whereas risk loci 8q24.21, 1p31.3, and 1q32.1 were reported in studies in White patients. Although the somatic mutational profiles of gliomas between East Asians and non-East Asians were broadly consistent, a lower incidence of EGFR amplification in glioblastoma and a higher incidence of 1p19q-IDH-TERT triple-negative low-grade glioma were observed in East Asian cohorts. By summarizing large-scale disease surveillance, germline, and somatic genomic studies, this review reveals the unique characteristics of adult diffuse glioma among East Asians, to guide clinical management and policy design focused on patients with East Asian ancestry.
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Lee, Rennie, Yue Qian, and Cary Wu. "Coethnic Concentration and Asians’ Perceived Discrimination across U.S. Counties during COVID-19." Socius: Sociological Research for a Dynamic World 8 (January 2022): 237802312211245. http://dx.doi.org/10.1177/23780231221124580.
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Aggregate figures unequivocally depict an increase in anti-Asian sentiment in the United States and other Western countries since the start of the COVID-19 pandemic, but there is limited understanding of the contexts under which Asians encounter discrimination. The authors examine how coethnic concentration shapes Asians’ experiences of discrimination across U.S. counties during COVID-19 and also assess whether county-level context (e.g., COVID-19 infection rates, unemployment rates) could help explain this relationship. The authors analyze the Understanding Coronavirus in America tracking survey, a nationally representative panel of American households, along with county-level contextual data. The authors find an n-shaped relationship between coethnic concentration and Asians’ perceived discrimination. This relationship is explained largely by county-level COVID-19 infection rates. Together, the context of medium Asian concentration and high COVID-19 cases created a particularly hostile environment for Asians during COVID-19.
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Li, Wenjun, and Vivian Lou. "AAA Research Methodology II: Innovative Observational and Intervention Studies." Innovation in Aging 4, Supplement_1 (December 1, 2020): 815. http://dx.doi.org/10.1093/geroni/igaa057.2968.
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Abstract Asians are the largest and the fastest growing segment of the world population, and the second largest immigrant population in the U.S. A high proportion of Asians live in developing countries or are immigrants to developed countries. Studies on age-related social and health issues of Asians have lagged. To advance research into aging among Asians living in the U.S. and elsewhere in the world, sound methodologies can be adopted from those well-developed in other settings while novel methodologies are to be developed to meet the unique needs of Asian studies. This symposium brings together five abstracts that address a variety of innovative methodological issues in social and health studies among Asian older adults. The topics range from use of wearable devices to measure travel patterns, life space and physical activity in late-life Asian immigrants in the U.S.; use of Ecological Momentary Assessment method to examine influences of social contact satisfaction on neighborhood affect in Chinese in mainland China; use of multilingual age-friendly touch-screen device for cognitive intervention in Singapore; use of GIS to evaluate potential influences of accessibility to neighborhood living resources on attitudes towards aging among the oldest old in Shanghai; and use of a multi-phase complex mixed methods to evaluate a Chinese cancer screening program in Taiwan. Together, these studies showed that innovative methods can be adapted for context relevance and linguistic and cultural appropriateness, and successfully executed in studies on aging among Asians. This symposium is a collaborative effort of the Aging Among Asians Interest Group.
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Pedraza, Chadrhyn A. A. "“There’s Something There in That Hyphen”: The Lived Experiences of Asian and Asian American Higher Education Students in the Southwest Borderlands of the United States." Genealogy 7, no. 1 (March 16, 2023): 22. http://dx.doi.org/10.3390/genealogy7010022.
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For centuries, Asians living in the U.S. have had to negotiate between the narratives that dominant society has imposed upon them and their understanding of what it means to be Asian and Asian American. When combined with the hierarchies of racial categories, the narratives underlying monoracialism are inherently limiting, obscuring their nuanced experiences, and stripping them of their ability to express the personal constructions of their identity The purpose of this qualitative case study was to elevate the voices of Asians and Asian Americans, their process of “inventing” their identity, and how their conceptualizations begin to deconstruct and challenge monoracialism. I argue that Asians and Asian Americans engage in a process where the interpretation and revision of meaning that emerges during interactions with others can illuminate the role of master narratives and how they negotiate between these structural factors and their ideas of what it means to be Asian or Asian American. The findings suggest a negotiation between master narratives at the macro-, meso-, and micro-societal levels that help them understand what it means to be Asian and Asian American.
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Wang, Ying, Toni K. Choueiri, Jae-Lyun Lee, Min-Han Tan, Sun Young Rha, Scott A. North, Christian K. Kollmannsberger, and Daniel Yick Chin Heng. "Vascular endothelial growth factor (VEGF) therapy in metastatic renal cell carcinoma (mRCC): Differences between Asian and non-Asian patients." Journal of Clinical Oncology 30, no. 5_suppl (February 10, 2012): 451. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.451.
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451 Background: Several reports have indicated that VEGF targeted therapy in metastatic renal cell carcinoma (mRCC) may be more toxic in the Asian versus Caucasian populations. Comparative efficacy of these agents with respect to ethnicity is not well characterized. Methods: Eight centers participating in the International mRCC Database Consortium with available dose reduction data on patients with mRCC treated with VEGF targeted therapy were included in this analysis. Asian patients were derived from centers in Korea and Singapore. Results: 1024 patients with a median follow-up of 29.4 months were included in this analysis. Baseline characteristics are below. The percentage of dose modifications/reductions between non-Asians and Asians was similar (55% vs 61% p=0.1197) but more patients completely discontinued treatment due to toxicity in the non-Asian vs the Asian group (28% vs 21% p=0.0197). When adjusted for the Heng et al poor prognostic criteria, there was no difference in overall survival (HR 0.887, 95%CI 0.729-1.08, p=0.2322) or progression-free survival (HR 1.069, 95%CI 0.910-1.256, p=0.4184) between non-Asians and Asians. Interestingly, when patients were dose reduced due to toxicity, they had a longer treatment duration and overall survival than those that did not require a dose reduction in both the non-Asian (10.6 vs 5.0 months p<0.0001 and 22.6 vs 16.1 months p=0.0016, respectively) and in the Asian populations (8.9 vs 5.4 months p=0.0028 and 28.0 vs 18.7 months p=0.0069). Conclusions: After adjusting for risk groups, there appears to be no difference in outcome between Asians vs. non-Asian patients with mRCC treated withVEGF-targeted therapy. Judicious dose reductions may allow for better outcomes in both populations possibly due to longer treatment durations, but direct comparisons are needed. [Table: see text]
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Chackathayil, Julia, Jeetesh V. Patel, Paramjit S. Gill, Rahul Potluri, Ammar Natalwala, Hardeep Uppal, Deepthi Lavu, Reinhard Heun, Elizabeth A. Hughes, and Gregory Y. H. Lip. "Cardiovascular Risk Profiles amongst Women in a Multiethnic Population in Inner City Britain: A Potential Impact of Anaemia." International Journal of Endocrinology 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/303859.
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The risk of diabetes is markedly reduced in men with iron deficiency anaemia (IDA). The nature of this relationship in women is not clear, nor is there information about the influence of ethnicity, given the increased susceptibility of diabetes amongst South Asians and Afro-Caribbeans. We reviewed 3563 patients with a diagnosis of anaemia from 2000 to 2007. The age-adjusted prevalence of vitamin B12 deficiency and IDA was calculated, together with cardiovascular comorbidities amongst Caucasians, South Asians, and Afro-Caribbeans. The prevalence of vitamin B12 deficiency (women only) or IDA was markedly higher in South Asians compared to Caucasians and Afro-Caribbeans. Among women with IDA, diabetes was more prevalent among South Asians (45%, 95% CI 39.0–51.0) compared to Caucasians (3.0%, 2.1–4.0);P<0.001. Among South Asian women with vitamin B12 deficiency, the prevalence of diabetes was reduced 8.5% (5.2–12.0). South Asian women with vitamin B12 deficiency had a higher prevalence of myocardial infarction (MI) and ischemic heart disease (IHD), but this relationship was reversed in IDA. IDA is associated with a greater prevalence of diabetes in South Asian women, but it is not coordinated by a greater risk of macrovascular complications. Given the cardiovascular impact of diabetes in South Asians, this association merits further study in relation to its pathophysiological implication.
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Tsai, Jiun-Yi, Joe Phua, Shuya Pan, and Chia-chen Yang. "Intergroup Contact, COVID-19 News Consumption, and the Moderating Role of Digital Media Trust on Prejudice Toward Asians in the United States: Cross-Sectional Study." Journal of Medical Internet Research 22, no. 9 (September 25, 2020): e22767. http://dx.doi.org/10.2196/22767.
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Background The perceived threat of a contagious virus may lead people to be distrustful of immigrants and out-groups. Since the COVID-19 outbreak, the salient politicized discourses of blaming Chinese people for spreading the virus have fueled over 2000 reports of anti-Asian racial incidents and hate crimes in the United States. Objective The study aims to investigate the relationships between news consumption, trust, intergroup contact, and prejudicial attitudes toward Asians and Asian Americans residing in the United States during the COVID-19 pandemic. We compare how traditional news, social media use, and biased news exposure cultivate racial attitudes, and the moderating role of media use and trust on prejudice against Asians is examined. Methods A cross-sectional study was completed in May 2020. A total of 430 US adults (mean age 36.75, SD 11.49 years; n=258, 60% male) participated in an online survey through Amazon’s Mechanical Turk platform. Respondents answered questions related to traditional news exposure, social media use, perceived trust, and their top three news channels for staying informed about the novel coronavirus. In addition, intergroup contact and racial attitudes toward Asians were assessed. We performed hierarchical regression analyses to test the associations. Moderation effects were estimated using simple slopes testing with a 95% bootstrap confidence interval approach. Results Participants who identified as conservatives (β=.08, P=.02), had a personal infection history (β=.10, P=.004), and interacted with Asian people frequently in their daily lives (β=.46, P<.001) reported more negative attitudes toward Asians after controlling for sociodemographic variables. Relying more on traditional news media (β=.08, P=.04) and higher levels of trust in social media (β=.13, P=.007) were positively associated with prejudice against Asians. In contrast, consuming news from left-leaning outlets (β=–.15, P=.001) and neutral outlets (β=–.13, P=.003) was linked to less prejudicial attitudes toward Asians. Among those who had high trust in social media, exposure had a negative relationship with prejudice. At high levels of trust in digital websites and apps, frequent use was related to less unfavorable attitudes toward Asians. Conclusions Experiencing racial prejudice among the Asian population during a challenging pandemic can cause poor psychological outcomes and exacerbate health disparities. The results suggest that conservative ideology, personal infection history, frequency of intergroup contact, traditional news exposure, and trust in social media emerge as positive predictors of prejudice against Asians and Asian Americans, whereas people who get COVID-19 news from left-leaning and balanced outlets show less prejudice. For those who have more trust in social media and digital news, frequent use of these two sources is associated with lower levels of prejudice. Our findings highlight the need to reshape traditional news discourses and use social media and mobile news apps to develop credible messages for combating racial prejudice against Asians.