Relevant bibliographies by topics / Ascorbic Acid Cataract

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Academic literature on the topic 'Ascorbic Acid Cataract'

Author: Grafiati
Published: 4 June 2021
Last updated: 13 February 2022

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Journal articles on the topic "Ascorbic Acid Cataract"

1

LOHMANN, W. "Ascorbic Acid and Cataract." Annals of the New York Academy of Sciences 498, no. 1 Third Confere (July 1987): 307–11. http://dx.doi.org/10.1111/j.1749-6632.1987.tb23769.x.

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2

Pokharel, Shailesh Mani, Poonam Lavaju, Bhuwan Govinda Shrestha, Seraj Ahmed Khan, and Sangeeta Shah. "Association of Plasma and Aqueous Humor Ascorbic Acid Level with Morphology Pattern of Age-Related Cataract." Journal of Nobel Medical College 9, no. 1 (June 17, 2020): 36–40. http://dx.doi.org/10.3126/jonmc.v9i1.29491.

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Background: Age-related cataract is one of the most important causes of preventable blindness among elderly population in the world. Among various causes of cataract, the level of ascorbic acid in the plasma and aqueous humor is an important parameter that can prevent cataract formation. The level of ascorbic acid in the plasma and aqueous humor is also an indicator of various morphological pattern of cataract. Materials and Methods: A hospital-based cross-sectional study was conducted among 136 patients with immature age-related cataract (≥50 years) who underwent Manual Small Incision Cataract Surgery in the Ophthalmology Department of BPKIHS for the duration of 1 year. Plasma and aqueous humor ascorbic acid levels were determined by standard competitive ELISA test. Results: Ascorbic acid concentrations in aqueous humor as well as plasma were statistically significant with the nuclear type of cataract (p<0.001). There was a positive correlation between plasma and aqueous ascorbic acid level with r = 0.532 and p<0.001. Conclusion: The finding of the study concludes that nuclear type of cataract has a strong association with both aqueous humor and plasma ascorbic acid level.
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3

Lohmann, W., M. Wunderling, W. Schmehl, J. Strobel, and K. G. Bensch. "Nuclear cataract and ascorbic acid." Naturwissenschaften 73, no. 5 (May 1986): 266–67. http://dx.doi.org/10.1007/bf00367780.

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4

Ringvold, Amund, Harald Johnsen, and Sigmund Blika. "Senile cataract and ascorbic acid loading." Acta Ophthalmologica 63, no. 3 (May 27, 2009): 277–80. http://dx.doi.org/10.1111/j.1755-3768.1985.tb06805.x.

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5

N. Mahajan, K., A. K. Singhai, and G. P. Vadnere. "Investigation on Anticataract Activity of Triphala Ghrita." E-Journal of Chemistry 8, no. 3 (2011): 1438–43. http://dx.doi.org/10.1155/2011/571627.

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Lab prepared Triphala ghrita was studied for its possible anticataract activity on galactose induced cataract in Swiss albino rats. Administration of Triphala ghrita at a dose of 216 mg/200 g, 1080 mg/200 g and 2160 mg/200 g of rat orally offered significant dose dependent protection against galactose induced cataract and delayed the onset and progression of cataract. It was seen that the dose of 1080 mg of Triphala ghrita did not show stage II cataract in 14 days and stage III in 21 days. It did not show even stage III and stage IV cataract after 30 days whereas group B and group C showed stage III and stage IV cataracts. Dose of 2160 mg did not showed stage IV cataract after 30 days but showed stage III cataract. Dose of 1080 mg of Triphala ghrita offered significant protection against delaying the onset and progression of cataract in comparison to other doses. This effect may be attributed to the antioxidant activity of gallic acid, ellagic acid and ascorbic acid which shows their presence in Triphala ghrita. This preliminary study was encouraging but further studies are required to extrapolate the clinical usefulness of this formulation.
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Bensch, K. G., J. E. Fleming, and W. Lohmann. "The role of ascorbic acid in senile cataract." Proceedings of the National Academy of Sciences 82, no. 21 (November 1, 1985): 7193–96. http://dx.doi.org/10.1073/pnas.82.21.7193.

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7

Aware, Rinkal R., Hemant J. Pagar, Ganesh D. Barkade, and Shweta Dhawane. "Anticataract activity of pioglitazone by using in-Vitro goat lens model." Indian Journal of Pharmacy and Pharmacology 8, no. 3 (September 15, 2021): 208–11. http://dx.doi.org/10.18231/j.ijpp.2021.036.

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In the present study we have selected antioxidants agents like Pioglitazone and Ascorbic acid were subjected for anti-cataract activity by in vitro glucose induced cataract model. In the procedure, goat lenses was incubated along with the aqueous humor solution containing 55mM glucose with Enalpril as a standard compound and Pioglitazone with varied concentration for the time interval of 72 hours at room temperature. There was a formation of blur layer on the goat eyeball occurs after 10-12 hours and this process complete after 72 hours. The cataract inducing lenses showing higher level of Na, MDA (P&#60;0.001) along with the decreases in sodium-potassium ATPase activity and water-soluble protein content. The goat lenses treated with Ascorbic acid 40 µg/ml and Pioglitazone in concentrations of 15, 30, and 60 µg/ml showed increased protein content and prevent the formation of cataract.
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8

Angirekula, Saseekala, Lalitsiri Atti, and Srihari Atti. "Estimation of serum ascorbic acid (vitamin C) in various morphological types and clinical stages of age related (senile cataract)." International Journal of Research in Medical Sciences 6, no. 3 (February 22, 2018): 893. http://dx.doi.org/10.18203/2320-6012.ijrms20180610.

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Background: The aim was to estimate the serum ascorbic acid (vitamin C) in the various morphological types and clinical stages of age related (senile) cataract, a common cause of curable blindness globally, especially in India.Methods: This was a study of estimation of serum ascorbic acid (vitamin C) in 100 cases of senile (age related) cataract with 60 cases of senile cortical type (30 cases of immature and 30 cases of mature) and 40 cases of senile nuclear type (20 cases of grades I and II and 20 cases of grades III and IV) in the age group of 45 to 70 years.Results: Vitamin C mean plasma level was significantly decreased in senile cataract (0.54±0.23mg/dl or 30.68±13.07umol) and in its morphological types of cortical and Nuclear, especially in the later stages or grades of maturity when compared with the earlier stages or grades of immaturity i.e. The mean level of Serum Ascorbic acid was 0.55±0.23 mg/dl ((31.25±13.07umol) in Senile Cortical cataract with 0.58±0.24 mg/dl (32.96±13.64umol) in its Immature stage and 0.52±0.20mg/dl (29.55±11.36umol) in its mature stage and the mean level in Senile Nuclear cataract was 0.54±0.23mg/dl (30.68±13.7umol) with 0.56±0.29mg/dl (31.82±16.48umol) in its Grades I and II and 0.52±0.22mg/dl (29.55±12.5umol) in its Grades III and IV.Conclusions: So, our study showed significantly decreased levels of serum vitamin C in all the morphological types and clinical stages of senile cataract especially in the later stages or grades of maturity compared to the earlier clinical stages or grades of immaturity.
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9

Ohta, Yoshiji, Takafumi Niwa, and Takashi Yamasaki. "Effect of Prolonged Marginal Ascorbic Acid Deficiency on Lenticular Levels of Antioxidants and Lipid Peroxide in Guinea Pigs." International Journal for Vitamin and Nutrition Research 71, no. 2 (March 1, 2001): 103–9. http://dx.doi.org/10.1024/0300-9831.71.2.103.

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We examined the effect of prolonged marginal ascorbic acid deficiency of the levels of antioxidants and lipid peroxide in lenses of guinea pigs in order to clarify lenticular antioxidant status under ascorbic acid deficiency. Male guinea pigs aged 4 weeks were given a scorbutic diet (20 g/animal per day) with either marginally deficient ascorbic acid (0.5 mg/animal per day) or sufficient ascorbic acid (1 g/animal per day) in drinking water for 3 and 6 months. The deficient group showed no lens opacity during the administration period. The deficient group had 62.3 and 53.9% of lenticular ascorbic acid content in the sufficient group at 3 and 6 months of ascorbic acid deficiency, respectively. There were no differences in lenticular contents of reduced glutathione and thiobarbituric acid reactive substances, an index of lipid peroxidation, between both groups at 3 and 6 months of ascorbic acid deficiency, while the deficient group tended to have higher lenticular vitamin E content than the sufficient group. The deficient group had higher serum vitamin E concentration than the sufficient group at 3 and 6 months of ascorbic acid deficiency. These results indicate that lenticular antioxidant status is maintained well in guinea pigs with prolonged marginal ascorbic acid deficiency, which may result in no cataract formation.
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10

Canadananovic, Vladimir, Slobodanka Latinovic, Sava Barisic, Nikola Babic, and Sandra Jovanovic. "Age-related changes of vitamin C levels in aqueous humour." Vojnosanitetski pregled 72, no. 9 (2015): 823–26. http://dx.doi.org/10.2298/vsp131212063c.

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Background/Aim. Age-related cataract is a common disease among senior population. Vitamin C is the most effective reducing hydrosoluble antioxidant causing reduction in the levels of free radicals in crystaline lens. The aim of this study was to evaluate the age-related change of vitamin C (L-ascorbic acid) level in the aqueous humor of patients with senile cataract. Methods. This prospective study included 74 patients, divided into 3 age groups, with age-related cataract, underwent routine phaco cataract surgery with intraocular lens implantation. Aqueous humor was aspirated from 74 eyes at the beginning of phacoemulsification. The levels of vitamin C (L-ascorbic acid) in aqueous humor were determined with high-performance liquid chromatography (HPLC). Results. The average age of patients included in the study was 65 ? 9.85 years (54-87 years). The level of vitamin C in aqueous humor was 152.78 ? 7.0125 ?g/mL in the group A (50-59 years), 134.15 ? 5.1569 ?g/mL in the group B (60-69 years) and 106.51 ? 5.44 ?g/mL in the group C (over 70 years). Conclusion. The amount of vitamin C in aqueous humor of patients with age-related cataract is decreasing with age. There was a statistically significant change (p < 0.001) of vitamin C aqueous concentration in the patients of different age. This decrease could play a role in susceptibility to cataract formation in older population.
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Dissertations / Theses on the topic "Ascorbic Acid Cataract"

1

Simpson, Gregory L. W. "A mechanism for ascorbate induced cataract in human lens." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3036856.

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