Academic literature on the topic 'Arterial grafts'

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Journal articles on the topic "Arterial grafts"

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SAITOH, S., and Y. NAKATSUCHI. "Arterial Grafting with the Telescoping Anastomotic Technique for Arterial Defects." Journal of Hand Surgery 19, no. 4 (August 1994): 461–65. http://dx.doi.org/10.1016/0266-7681(94)90211-9.

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An arterial graft was taken from the left femoral artery of the rat and grafted into the right femoral artery using the telescoping anastomotic technique at both the proximal and distal anastomoses to compare the patency rate with that of the vein grafts interposed into the arterial defect with the same telescoping technique. The time required for each anastomosis was about 10 minutes and all of the 31 grafts remained patent without application of xylocaine, yielding a higher patency rate than the vein grafts interposed in an arterial defect. The telescoping technique proved to be so dependable that it could be used at least twice in an artery. Inserting one vessel stump into another using the telescoping technique may not itself be responsible for the failure of vein grafts interposed in an arterial defect, but distortion of the slack venous wall of the graft by high arterial blood pressure is.
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Toia, Francesca, Giovanni Zabbia, Tiziana Roggio, Roberto Pirrello, Adriana Cordova, and Salvatore D'Arpa. "Vascular Grafts and Flow-through Flaps for Microsurgical Lower Extremity Reconstruction." Journal of Reconstructive Microsurgery 33, S 01 (October 2017): S14—S19. http://dx.doi.org/10.1055/s-0037-1606560.

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Background The use of vascular grafts is indicated in case of insufficient pedicle length or for complex defects involving both soft tissues and vessels. Venous grafts (for both venous and arterial reconstructions) and arterial grafts (arterial reconstruction) can be used. This study retrospectively evaluated the needs for vascular reconstruction and its results in a clinical series of lower limb reconstructions with microsurgical free flaps. Materials and Methods From 2010 to 2015, a total of 16 vascular grafts or flow-through flaps were used in 12 patients out of a total of 150 patients undergoing microsurgical reconstruction (8%). Arterial reconstruction was performed in seven cases (six flow-through flaps, one arterial graft), combined arterial and venous reconstruction in four cases (three vein grafts, one combined venous/arterial graft), and venous reconstruction in one case (one venous graft). The rate of complications and donor-site morbidity related to vascular graft harvest were evaluated. Results Reconstruction was successful in all cases, despite an overall complication rate of 17 and 8% of surgical revision. Donor-site morbidity, subjectively evaluated, was minimal with respect to functional deficits and aesthetic outcome. Indications for the different types of grafts are discussed. Conclusion The use of vascular grafts is needed in a relevant percentage of microsurgical reconstruction cases. Venous and arterial vascular grafts, transient arteriovenous fistulas, and “flow-through” microsurgical flaps showed a safe reconstruction comparable to microsurgical reconstructions without the use of grafts. Donor-site morbidity secondary to vascular graft harvest is minimal, and in almost 70% of cases no additional scars are needed.
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Haverich, A., and H. G. Borst. "Arterial grafts." Current Opinion in Cardiology 5, no. 6 (December 1990): 737–41. http://dx.doi.org/10.1097/00001573-199012000-00003.

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Amin, Sanaz, Per Lav Madsen, Raphael S. Werner, George Krasopoulos, and David P. Taggart. "Intraoperative flow profiles of arterial and venous bypass grafts to the left coronary territory." European Journal of Cardio-Thoracic Surgery 56, no. 1 (January 31, 2019): 64–71. http://dx.doi.org/10.1093/ejcts/ezy473.

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Abstract OBJECTIVES The different mechanical and vasodilatory properties of arteries and veins may influence their flow profiles when used for coronary artery bypass grafting (CABG). This may be of significance when assessing the cut-off values for adequate flow. However, conduit-related flow differences are less examined. METHODS In a study of 268 patients, transit time flowmetry parameters of 336 arterial and 170 venous conduits all grafted to the left coronary territory were compared. With transit time flowmetry, the mean graft flow (MGF), pulsatility index, percentage of diastolic filling and percentage of backwards flow were measured. Conduit-related differences were further compared according to on- or off-pump CABG (ONCABG versus OPCABG) surgery. RESULTS Overall MGF and pulsatility index were comparable between arterial and venous grafts, but in arterial grafts, MGF was higher during ONCABG than during OPCABG (49.1 ± 35.3 ml/min vs 38.8 ± 26.6 ml/min; P = 0.003). Percentage of diastolic filling was higher in arterial grafts than in venous grafts (overall 71.0 ± 7.9% vs 63.7 ± 11.1%; ONCABG 69.9 ± 7.1% vs 63.9 ± 10.4%; OPCABG 71.9 ± 8.3% vs 63.4 ± 12.2%; all P < 0.001). Furthermore, percentage of backwards flow was higher in arterial grafts than in venous grafts in the overall (2.3 ± 3.2% vs 1.7 ± 3.2%, P = 0.002) and in the ONCABG (2.3 ± 3.2% vs 1.3 ± 2.5%, P < 0.001) cohorts. In venous grafts, percentage of backwards flow was lower during ONCABG versus OPCABG (1.3 ± 2.5% vs 2.6 ± 3.9%, P = 0.016). CONCLUSIONS No statistically significant difference was observed for MGF and pulsatility index between arterial and venous conduits. However, arterial grafts have significantly higher diastolic filling and backwards flow than venous grafts. Furthermore, arterial grafts have a significantly higher MGF in ONCABG versus OPCABG.
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Csébi, Péter, Csaba Jakab, Attila Patonai, Attila Arany-Tóth, László Kóbori, and Tibor Németh. "Morphological evaluation of experimental autologous rectus fascia sheath vascular grafts used for arterial replacement in a dog model." Acta Veterinaria Hungarica 62, no. 4 (December 1, 2014): 429–38. http://dx.doi.org/10.1556/avet.2014.025.

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Although experimental autologous patch or tubular conduit vascular grafts made from the internal rectus fascia sheath (IRFS) have been reported in the literature, thorough morphological evaluation and verification of the histological arterialisation of such grafts are lacking. Four purpose-bred Beagle dogs were utilised to create eight arterial internal rectus fascia sheath (ARFS) grafts implanted between bisected ends of the external iliac arteries. Four out of the eight ARFS grafts were patent after three months. Haematoxylin-eosin and Azan staining verified that the grafts gained a vessel-like layered structure with the presence of large amounts of collagen fibres. Although the inner surface of the intact IRFS was originally covered with claudin-5-negative and pancytokeratin-positive mesothelial cells in control samples, the internal cells of the ARFS grafts became claudin-5 positive and pancytokeratin negative like in intact arteries. Spindle-shaped cells of the wall of ARFS grafts were α-smooth muscle actin (α-SMA) positive just like the smooth muscle cells of intact arteries, but α-SMA immunoreactivity was negative in the intact IRFS. According to these findings, the fibroblast cells of the ARFS graft have changed into myofibroblast cells. The study has proved that ARFS grafts may be used as an alternative in arterial replacement, since the graft becomes morphologically and functionally similar to the host vessel via arterialisation.
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Watanabe, Go, Tamotsu Yasuda, and Shigeyuki Tomita. "A Multipurpose Arterial Graft Holder for Coronary Artery Bypass Grafting." Heart Surgery Forum 8, no. 2 (March 9, 2005): 98. http://dx.doi.org/10.1532/hsf98.2005-1001.

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A multipurpose arterial graft holder designed for use during coronary artery bypass grafting is described. This new holder is atraumatic and holds the arterial grafts and saphenous vein graft securely during anastomosis. The use of this instrument facilitates the use of multiple arterial grafts for coronary artery bypass grafting.
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Rashid, Harun Or, AKM Anwarul Islam, AKM Khursidul Alam, Md Sajid Hasan, and Md Habibur Rahman Dulal. "Comparative Study of Short-Term Outcome of Live Related Renal Transplantation From Grafts Having Single vs Multiple Arteries." Bangladesh Journal of Urology 17, no. 1 (September 14, 2020): 9–16. http://dx.doi.org/10.3329/bju.v17i1.49108.

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Objective: To compare the outcome of live related renal transplantation between the Grafts having single vs multiple arteries. Materials and Methods: The data of 94 renal transplants with single and multiple arteries performed between January 2011 and December 2012 were collected from Bangabandhu Sheikh Mujib Medical University and National Kidney Foundation. Sixty three renal transplants with single renal artery were compared to 31 transplants with multiple arteries. The aspects analyzed were number of arteries of the graft, donor type, ischemia time, time spent for arterial anastomosis, time spent for total vascular anastomosis and time for whole operation, vascular reconstruction technique, the occurrence of surgical complications, the incidence of delayed graft function, graft function 6 month after transplantation, graft loss and mortality. Results: The incidence of surgical complications in grafts with single artery and multiple renal artery was respectively: vascular 6.4% and 3.2%; urological 13.2% and 9.6%, other surgical complications was 3,2% and 3.2%, and the difference were not significant among the two groups. Symptomatic lymphocele was 3.2% observed in single artery group but the incidence of lymphoceles was 6.4% in grafts with multiple arteries (p < 0.005). The incidence of delayed graft function in grafts with a single artery and multiple arteries was respectively 6.4% and 6.4% (p =<0.005). Mean serum creatinine at the end of 6th months of postoperative period was 1.33mg/dl and 1.67 mg/dl in grafts with single and multiple arteries respectively (p<0.005). Cold ischemia time, preparation time duration of in vivo arterial anastomosis and the total length of operation time was significantly longer in the multiple artery group(p<0.005). Six months grafts survival in single and multiple artery was 88.9% and 87.1% respectively. Conclusions: Kidney transplantation using grafts having single and multiple arteries present similar indeces of surgical complications and short-term outcome. Though, lymphoceles was more frequent among grafts with multiple arteries but the difference were not significant among the two groups. In other words. Live related renal transplantation from grafts having multiple arteries is safe and has a good outcome. Bangladesh Journal of Urology, Vol. 16, No. 1, Jan 2014 p.9-16
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Patel, Dinesh L., Yashpal R. Rana, Megha M. Sheth, Samir G. Patel, and Milin N. Garachh. "MSCT coronary angiography in non-invasive assessment of coronary artery bypass grafts patency." International Journal of Research in Medical Sciences 7, no. 5 (April 26, 2019): 1413. http://dx.doi.org/10.18203/2320-6012.ijrms20191626.

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Background: Coronary artery disease (CAD) is one of the leading cause of the morbidity and mortality in India and worldwide and last decade has seen a steep rise in incidence of CAD in India and its treatment as bypass surgery. Direct visualization of the grafts and native coronary arteries by invasive catheterization is now being replaced by non-invasive CT coronary angiography with higher slice machines and newer technology as it has good temporal resolution, high scanning speed as well as low radiation dose. We share our experience of graft imaging on 128 slice CT machine.Methods: This is a retrospective, single-center, observational study. We included 500 symptomatic patients who have undergone CT study between the year 2014 to 2018 post bypass surgery.Results: Arterial grafts have a better patency rate than venous grafts. (88% vs. 64.1%). Amongst the individual arterial grafts RIMA had the best patency rate (100%) followed by LIMA (90.8%), RA (68.7%). LAD was the most commonly involved artery (91%).Conclusions: Significant absolute concordance between CT and catheter angiographic findings have been documented for all arterial and venous grafts patency in the literature. The MSCT with retrospective gating permits an accurate and non-invasive evaluation of patent and diseased arterial and vein grafts and could replace conventional angiography for the follow-up of symptomatic, stable patients. Moreover, an optimal diagnostic accuracy was also documented in the appraisal of native vessels distal to the graft anastomoses.
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Tribble, Curtis G. "The Skeleton in the Closet: Harvesting a Skeletonized IMA." Heart Surgery Forum 20, no. 4 (August 28, 2017): 178. http://dx.doi.org/10.1532/hsf.1867.

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There is a considerable amount of data that using more than one arterial graft provides a survival advantage for patients undergoing coronary bypass operations. The Society of Thoracic Surgeons has a set of official guidelines for the use of arterial grafts which include the following recommendations:Internal mammary arteries (IMA’s) should be used to bypass the left anterior descending (LAD) artery when bypass of the LAD is indicated.As an adjunct to left internal mammary artery (LIMA), a second arterial graft (right IMA or radial artery [RA]) should be considered in appropriate patients.Use of bilateral IMA’s (BIMA’s) should be considered in patients who do not have an excessive risk of sternal complications.To reduce the risk of sternal infection with bilateral IMA’s, skeletonized grafts should be considered, smoking cessation is recommended, glycemic control should be considered, and enhanced sternal stabilization may be considered.Use of arterial grafts should be a part of the discussion of the heart team in determining the optimal approach for each patient. [Ann Thorac Surg 2016; 101: 801–9]
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Kawashima, Masatou, Albert L. Rhoton, Necmettin Tanriover, Arthur J. Ulm, Alexandre Yasuda, and Kiyotaka Fujii. "Microsurgical anatomy of cerebral revascularization. Part I: Anterior circulation." Journal of Neurosurgery 102, no. 1 (January 2005): 116–31. http://dx.doi.org/10.3171/jns.2005.102.1.0116.

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Object. Revascularization is an important component of treatment for complex aneurysms that require parent vessel occlusion, skull base tumors that involve major vessels, and certain ischemic diseases. In this study, the authors examined the microsurgical anatomy of cerebral revascularization in the anterior circulation by demonstrating various procedures for bypass surgery. Methods. Twenty-five adult cadaveric specimens were studied, using 3 to 40 magnification, after the arteries and veins had been perfused with colored silicone. The microsurgical anatomy of cerebral revascularization in the anterior circulation was examined with the focus on the donor, recipient, and graft vessels. The techniques discussed in this paper include the superficial temporal artery (STA)—middle cerebral artery (MCA), middle meningeal artery (MMA)—MCA, and side-to-side anastomoses; short arterial and venous interposition grafting; and external carotid artery/internal carotid artery (ICA)—M2 and ICA—ICA bypasses. Bypass procedures for cerebral revascularization are divided into two categories depending on their flow volume: low-flow and high-flow bypasses. A low-flow bypass, such as the STA—MCA anastomosis, is used to cover a relatively small area, whereas a high-flow bypass, such as the ICA—ICA anastomosis, is used for larger areas. Cerebral revascularization techniques are also divided into two types depending on the graft materials: pedicled arterial grafts, such as STA and occipital artery grafts, and free venous or arterial grafts, which are usually saphenous vein and radial artery grafts. Pedicled arterial grafts are mainly used for low-flow bypasses, whereas venous or arterial grafts are used for high-flow bypasses. Conclusions. It is important to understand the methods of bypass procedures and to consider indications in which cerebral revascularization is needed.
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Dissertations / Theses on the topic "Arterial grafts"

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Bass, David Hyman. "Infra-inguinal arterial bypass procedures at Groote Schuur Hospital, 1977-1983 : analysis and evaluation of results." Master's thesis, University of Cape Town, 1987. http://hdl.handle.net/11427/26248.

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Infra-inguinal arterial bypass is becoming increasingly popular as a means of alleviating incapacitating symptoms of atherosclerosis and other progressive diseases affecting the arteries of the lower limb. The role of this procedure in limb salvage is controversial but an aggressive attitude is emerging from many centres. It is accepted that the majority of atherosclerotic patients have a short life expectancy but reconstructive vascular surgery has an important role to play in improving their quality of life. Progress in infra-inguinal bypass surgery has centred mainly on the development of synthetic grafts but the perfonnance of autologous saphenous vein has not been bettered in terms of longterm results and cost-effectivity. The initial experience of infra-inguinal bypass at Groote Schuur Hospital, Cape Town, is examined retrospectively with the objective of demonstrating the possible influence of patient factors and specific surgical practices on the outcome of results.
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Griffis, Jack C. III. "Design of a mechanism for generating axial arterial distraction in-vivo." Thesis, Georgia Institute of Technology, 2002. http://hdl.handle.net/1853/16795.

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Papaharilaou, Yannis. "Studies of fluid flow in arterial bypass grafts by magnetic resonance imaging." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271254.

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Kumar, Vivek Ashok. "Design and evaluation of scaffolds for arterial grafts using extracellular matrix based materials." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/45869.

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For small diameter (<6 mm) blood vessel replacements, lack of collaterals and vascular disease preclude homografts; while synthetic analogs, ePTFE, expanded polytetrafluoroethylene, and PET, polyethyleneterephathalate, are prone to acute thrombosis and restenosis. It is postulated that the hierarchical assembly of cell populated matrices fabricated from protein analogs provides a new design strategy for generating a structurally viable tissue engineered vascular graft. To this end, synthetic elastin and collagen fiber analogs offer a novel strategy for creating tissue engineered vascular grafts with mechanical and biological properties that match or exceed those of native vessels. This work details techniques developed for the fabrication of prosthetic vascular grafts from a series of extracellular matrix analogs composed of nanofibrous collagen matrices and elastin-mimetic proteins, with and without cells, and subsequent evaluation of their biocompatibility and mechanical properties. The work details the fabrication and mechanical analysis of vascular grafts made from aforementioned protein analogs. Subesequent studies detail seeding and proliferation of rodent mesenchymal stem cells on protein-based composites to recapitulate the media of native vasculature. Finally detailing in vivo biocompatibility and stability of tissue engineered vascular grafts.
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Giordana, Sergio. "Geometrical reconstruction from medical images, classification and modelling of arterial by-pass grafts." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411719.

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Beattie, David Keith. "The influence of altered haemodynamics on human smooth muscle cell behaviour." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369122.

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Muir, A. D. "A comprehensive investigation of the mechanisms that underlie differences between venous and arterial grafts." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446127.

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Nelson, Gregory. "Studying the development of human tissue-engineered arterial grafts in a chimeric mouse model." [New Haven, Conn. : s.n.], 2008. http://ymtdl.med.yale.edu/theses/available/etd-12092008-145012/.

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Huang, Henry Yen-Chin Graduate School of Biomedical Engineering Faculty of Engineering UNSW. "Theoretical and experimental modelling of stress within the neck of endoluminal grafted artery." Awarded by:University of New South Wales. Graduate School of Biomedical Engineering, 2006. http://handle.unsw.edu.au/1959.4/29146.

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The success of endoluminal stent-graft treatment for abdominal aortic aneurysm relies on maintenance of an effective seal when the stent expands into the healthy artery. Clinical observation of aortic neck dilation following endoluminal grafting has led to the hypothesis that excessive stent expansion forces may cause remodelling and dilation of the artery to accommodate the strong forces. This may lead to failure of the seal, hence so-called endoleak. In this research, we analysed the force field generated by aortic stent-grafts and investigated in vitro approaches for studying the effects of these forces on cells within the vascular wall. The pressure-deformation behaviour of ovine arteries was examined experimentally and was found to vary with artery type. A finite element model of abdominal aorta (AA) characterised by Mooney-Rivlin hyperelastic material properties was validated. The property inputs were derived from the polynomial form of the strain energy density function proposed by Patel and Vaishnav. Stent-artery contact simulations revealed stresses 1.2-19 times higher than within a normal vessel at 120 mmHg when contacted by a zig-zag, square cross-section stent that expanded the AA by 3-16%. Streses 1.3-23 times normal were predicted for circular cross-section stents at the same range of expansions. The stress distribution was determined to be concentrated at the contacting surface and within the inner region of the aortic wall. These results confirmed that the forces within the vessel wall are likely to place unnatural physiological demands on the cells within. We then developed an in vitro system for studying the impact of this mechanical stress on cells within a three dimensional (3D) structure. A 20 wt% poly(vinyl alcohol) (PVA) - 5 wt% collagen tubular construct was developed to support cells, and was shown to sustain physiological blood pressures. Two cell-seeding techniques were examined, direct cell encapsulation and surface cell-seeding. Both demonstrated the capability of entrapping viable cells within the construct that remained viable for up to 4 days. In conclusion, stent contact does create abnormal stress concentrations within the vessel wall with a magnitude severely higher than physiological levels. A feasible tubular construct and an in vitro system were developed, enabling further assessments on the effects of these abnormality on the cells.
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Jones, Sion Gwyn. "The role of stem cells in the cellular accumulation on decellularised human arterial grafts in vivo." Thesis, St George's, University of London, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589942.

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Background: Coronary artery disease is a common condition that affects over a million people in the United Kingdom. Treatment options are medical management, surgical or percutaneous revascularisation. The choice between surgical and percutaneous intervention is guided by the severity of the disease, with surgical intervention offering superior outcomes as the severity of disease increases. However, some patients lack suitable conduits for a surgical procedure or develop stenosis within these grafts. The field of stem cell biology is rapidly expanding and together with the concepts of tissue engineering offers the promise of growing autologous grafts in the laboratory. Methods: Human arterial samples were collected and decellularised using an ionic detergent. These vessel scaffolds were then used as grafts in an in vivo mouse model and the cellular accumulation on them was examined both histologically and by cell culture with assessment of their physiological properties. Results: LIMA branches were fully decellularised and successfully implanted into a murine model. Grafts were repopulated by cells expressing stem cell markers (CD3l, CD34) and subsequently expressed markers of mature endothelial cells (v on Willebrand Factor) as well as smooth muscle cell markers (calponin, myosin heavy chain). The migratory capacity of the cultured cells was found to be significantly higher than that of mouse smooth muscle cells (p
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Books on the topic "Arterial grafts"

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Kunov, Mads J. Numerical simulation and visualization of blood flow in arterial bypass grafts. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1993.

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Arterial grafting for myocardial revascularization: Indications, surgical techniques, and results. Berlin: Springer-Verlag, 1990.

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Peripheral endovascular interventions. 3rd ed. New York: Springer, 2010.

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Smith, Frank C. T. Augmentation of arterial graft blood flow. Birmingham: University of Birmingham, 1998.

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L, Henry Mitchell, ed. Vascular access for hemodialysis IX. Los Angeles: Bonus Books, 2005.

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1956-, Calligaro Keith D., and Veith Frank J. 1931-, eds. Management of infected arterial grafts. St. Louis, Mo: Quality Medical Pub., 1994.

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D, Angelini Gianni, Bryan Alan J, and Dion Robert M. D, eds. Arterial conduits in myocardial revascularization. London: Arnold, 1996.

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Cooley, D. A., and Guo-Wei He. Arterial Grafting for Coronary Artery Bypass Surgery. Springer London, Limited, 2006.

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He, Guo-Wei, and D. A. Cooley. Arterial Grafting for Coronary Artery Bypass Surgery. Springer, 2010.

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Niccoli, Giampaolo, and Ingo Eitel. Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment. Elsevier Science & Technology, 2018.

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Book chapters on the topic "Arterial grafts"

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How, T. V. "Mechanical Properties of Arteries and Arterial Grafts." In Cardiovascular Biomaterials, 1–35. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1847-3_1.

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Stone, Patrick A., and Dennis F. Bandyk. "Duplex Surveillance of Infrainguinal Bypass Grafts." In Noninvasive Peripheral Arterial Diagnosis, 57–67. London: Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-955-8_6.

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Calafiore, A. M., and M. Di Mauro. "Complex Arterial Grafts: Operative Techniques." In Arterial Grafting for Coronary Artery Bypass Surgery, 243–47. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-30084-8_31.

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Calafiore, A. M., and M. Di Mauro. "Complex Arterial Grafts: Clinical Results." In Arterial Grafting for Coronary Artery Bypass Surgery, 248–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-30084-8_32.

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Bide, Martin, Matthew Phaneuf, Frank LoGerfo, William Quist, and Michael Szycher. "Arterial Grafts as Biomedical Textiles." In ACS Symposium Series, 125–54. Washington, DC: American Chemical Society, 2001. http://dx.doi.org/10.1021/bk-2001-0792.ch009.

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Kolakowski, Stephen, Keith D. Calligaro, Sandy McAffe-Benett, Kevin J. Doerr, Kathy Mueller, and Matthew J. Dougherty. "Rationale and Benefits of Surveillance After Prosthetic Infrainguinal Bypass Grafts." In Noninvasive Peripheral Arterial Diagnosis, 69–74. London: Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-955-8_7.

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Claessen, Bimmer E. P. M., José P. S. Henriques, and George D. Dangas. "Percutaneous Coronary Intervention of Arterial and Vein Grafts." In Interventional Cardiology, 201–4. Chichester, UK: John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118983652.ch19.

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van Son, J. A. M., F. M. M. Smedts, C. Q. Yang, and G. W. He. "Histology and Comparison of Arterial Grafts Used for Coronary Surgery." In Arterial Grafting for Coronary Artery Bypass Surgery, 3–16. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-30084-8_1.

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Wissink, M. J. B., and J. Feijen. "Tissue-Engineered Vascular Grafts for Small-Diameter Arterial Replacement." In Polymer Based Systems on Tissue Engineering, Replacement and Regeneration, 391–405. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-010-0305-6_21.

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Sabik, Joseph F., and Bruce W. Lytle. "Role of Internal Thoracic Artery Grafts in Reoperative Coronary Artery Bypass Surgery." In Arterial Grafting for Coronary Artery Bypass Surgery, 269–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-30084-8_35.

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Conference papers on the topic "Arterial grafts"

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Chidlow, A., A. C. Meek, I. F. Lane, P. Pate, and C. N. McCollum. "THE THROMBOGENICITY OF PTFE ARTERIAL GRAFTS INCREASES IN THE WEEKS FOLLOWING IMPLANTATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643087.

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Despite few failures in the initial weeks, polytetrafluoro-ethylene (PTFE) femoro-popliteal grafts, which have a non-thrombogenic flow surface, frequently occlude between 2 and 6 months following implantation [1]. Radiolabelled platelet uptake was studied during this risk period.In 20 greyhounds, 6cm lengths of 6mm PTFE were implanted in the femoral artery and autologous 111In-platelet accumulation measured 1 and 8 weeks later. Radioactivity over the graft was compared to the contralateral thigh and the daily rise in this ratio expressed as the Thrombogenicity Index (TI). At 8 weeks the graft was excised, 111In-platelet content counted in a well crystal and pseudointimal hyperplasia measured by grid microscopy.Mean (± sem) TI of 0.054±0.02 at 1 week almost doubled in the grafts that remained patent at 8 weeks to 0.10±0.02 (p<0.05). Radioactivity on the excised grafts was 0.012±0.0027 percent of injected activity and this correlated closely with TI at 8 weeks (r=0.83, p<0.001). Even in grafts remaining patent, this late accumulation of radiolabelled platelets correlated closely (r=0.63, p<0.02) with pseudointimal hyperplasia which narrowed the graft by a mean of 18±4.7 percent of luminal area.PTFE grafts had a low initial thrombogenicity which increased by the second month. This rising thrombogenicity, which presumably follows luminal deposition of fibrin and platelets, is associated with pseudointimal hyperplasia which may explain why these grafts frequently occlude in the months following discharge from hospital.1. Veith FJ, Gupta S, Daly V. Management of early and late thrombosis of expanded PTFE femoro-popliteal bypass grafts. Surgery 1980; 87: 531-587.
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2

El-Kurdi, Mohammed S., Brian C. Morelli, Yi Hong, William R. Wagner, and David A. Vorp. "In Situ Bioengineering of Arterial Vein Grafts." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192761.

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The autogenous saphenous vein remains the graft of choice for both coronary (500,000 annually in the US)1 or peripheral (80,000 annually)2 arterial bypass procedures. Failure of arterial vein grafts (AVGs) remains a major problem, and patients with failed grafts will die or require re-operation. Intimal hyperplasia (IH) accounts for 20% to 40% of all AVG failures3. It is believed that this adverse pathological response by AVGs is largely due to their abrupt exposure to the significantly elevated circumferential wall stress (CWS) associated with the arterial system4. We believe that if an AVG is given an ample opportunity to adapt and remodel to the stresses of its new environment, cellular injury may be reduced, thus limiting the initiating mechanisms of IH. The goal of this work was to develop a new mechanical conditioning paradigm, in the form of a peri-adventitially placed, biodegradable polymer wrap, to safely and functionally “arterialize” AVGs in situ. The electrospun polymer wrap was tuned so that as it degraded over a desired period of time, the mechanical support offered by it was reduced gradually, and hence the vein was exposed to slowly increasing levels of CWS in situ.
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3

MacLennan, M. J., B. J. Leavitt, J. D. Schmoker, and N. C. Chesler. "Pressure Increases Inert Particle Uptake in Human Saphenous Vein." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2234.

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Abstract Cardiovascular disease is one of the leading causes of death in the United States, and coronary artery bypass graft surgery (CABG) is one of the mainstays of treatment for this disease [1]. Since artificial vascular grafts suitable for coronary bypass are not yet available, autologous internal mammary artery (IMA) and saphenous vein are used to bypass diseased tissue [1]. While IMA grafts have high long-term patency rates, saphenous vein grafted into the arterial position tends to stenose and eventually thrombose.
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4

MacLennan, M. J., B. J. Leavitt, J. D. Schmoker, and N. C. Chesler. "Pressure Increases Inert Particle Uptake in Human Saphenous Vein." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2572.

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Abstract Cardiovascular disease is one of the leading causes of death in the United States, and coronary artery bypass graft surgery (CABG) is one of the mainstays of treatment for this disease (Niklason et al., 1999). Since artificial vascular grafts suitable for coronary bypass are not yet available, the autologous internal mammary artery (IMA) and saphenous vein are used to bypass diseased tissue (Niklason et al., 1999). While IMA grafts have high long-term patency rates, a saphenous vein grafted into the arterial position tends to stenose and eventually thrombose.
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5

Franz, Thomas, Helena van der Merwe, Peter Zilla, Deon Bezuidenhout, and B. Daya Reddy. "Tubular Nitinol Knit Meshes for External Reinforcement of Saphenous Vein Grafts: A Numerical Design Study." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-68624.

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The difference in mechanical properties between grafts and host arteries is a complicating factor for vascular bypass surgery and can cause patho-physiological problems after implantation [1–7]. Diffuse and focal intimal hyperplasia, one of the key factors of vein graft failure, has been attributed to over-distension and diametric irregularities of the veins when exposed to the arterial circulation [8]. The external reinforcement of saphenous vein grafts with open-mesh knitted Nitinol structures is suggested to prevent over-distension, smooth the luminal diameter, and address the mismatch in mechanical properties of vein graft and host vessel. The objectives of this work were: 1) development of Finite Element (FE) models of knitted Nitinol structures to assess mechanical behaviour and structural properties, e.g. vascular compliance, and 2) proof of feasibility of the FE method developed for structural design optimisation of the Nitinol mesh.
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6

Quee, Shawn Chin, Hai-Chao Han, and David N. Ku. "Bench-Top Validation Tests for Tissue-Engineered Arteries." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2514.

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Abstract Standard tests are needed for evaluating and comparing the mechanical and biological functions of tissue engineered arteries and other vascular grafts. We propose an ex vivo organ culture system as a living system for testing tissue-engineered vascular grafts. This bench-top organ culture system mimics the physiological environment of arteries including the flow, pressure, and the axial stretch. Arterial mechanical properties and physiologic functions including compliance, burst pressure, and contractile functions can be assessed before an expensive long-term animal test is initiated. Test results of natural arteries indicate that organ culture is a valid model for comprehensive evaluation of tissue-engineered vascular grafts.
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7

Vardoulis, Orestis, Eline Coppens, Bryn Martin, Philippe Reymond, and Nikos Stergiopulos. "Assessment of Aortic Graft Impact on Hemodynamics." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53245.

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In vivo studies have revealed that aortic grafts augment heart load and alter blood pressure and flow waveforms [1]. A one-dimensional model of the arterial tree was developed in order to analyze the different mechanisms by which proximal and distal aortic grafts affect hemodynamics. Graft compliance and properties were based on in vitro tests. Predicted pressures at the aortic root were compared for the control, proximal and distal graft case. Pulse pressure increased by 21% and 10% in presence of a proximal and distal graft, respectively. The distal graft resulted in a wave reflection coefficient of 0.62 while for the proximal graft the wave reflection coefficient was 0.46. The physiological mechanism behind the rise of pressure is dual and it is critically affected by the graft’s compliance and position. In case of a proximal graft, the primary reason for aortic pressure increase is the augmentation of aortic characteristic impedance, which augments the forward running pressure wave, while for the distal graft the wave reflections are major contributors to the total pressure wave. Overall, the proximal graft altered hemodynamics to a greater extent than a distal aortic graft.
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8

Wang, Qiang, Wei He, Yi Hong, William R. Wagner, and David A. Vorp. "Microfibrillar Elastic Polymer Wrapping of Rat Vena Cava for the Study of Engineered Arterial Vein Grafts." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19460.

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The autologous saphenous vein graft remains the graft of choice for 95% of surgeons performing coronary artery or peripheral bypass procedures. Within the first 5 years after implantation, 20%–40% of arterial vein grafts (AVG) fail due to intimal hyperplasia (IH)1. This adverse pathological response by AVGs may be in part due to their abrupt exposure to the significantly elevated circumferential wall stress associated with the arterial system2. We believe that if an AVG is given an ample opportunity to adapt and remodel to the stresses of the arterial environment, cellular injury may be reduced, thus limiting the initiating mechanisms of IH.
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9

Ballyk, Peter D., Matadial Ojha, and Colin Walsh. "Vein Cuffs May Improve Anastomotic Patency by Reducing Suture-Line Intramural Stresses." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0258.

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Abstract Intimal hyperplasia (IH) is an important complication of arterial bypass surgery which can ultimately lead to graft failure. The pathogenesis of IH involves the migration of smooth muscle cells from the media to the intima where they proliferate and secrete extracellular matrix. This results in a thickened vessel wall which may cause stenosis and/or thrombosis of the distal graft-artery junction. It has been shown that IH is a more significant problem in stiff synthetic grafts than in more compliant vein grafts (Bassiouny et al., 1992), and that synthetic grafts have a higher failure rate (Waiden et al., 1980). Consequently, autogenous vein (or artery) grafts are used clinically whenever possible. In cases where autogenous grafts are not long enough or not available (for e.g. if they have already been harvested or have been obliterated by disease), a vein cuff interposed between the distal end of a synthetic graft and the host artery can improve long term patency by reducing distal anastomotic IH (Miller et al., 1984; Suggs et al., 1988).
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10

Ramachandra, Abhay B., Sethuraman Sankaran, Jay D. Humphrey, and Alison L. Marsden. "Growth and Remodeling of Vein Graft in an Arterial Environment: Parameter Estimation and Sensitivity Analysis." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14617.

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In coronary artery disease, surgical revascularization using venous bypass grafts is performed to relieve symptoms and prolong life. Coronary bypass graft surgery is performed on approximately 500,000 people every year in the United States, with graft failure rates as high as 50% within 5 years. When a vein graft is implanted in the arterial system it adapts to the high flow rate and high pressure of the arterial environment by changing composition and geometry. Hemodynamics is known to play an active role in growth and remodeling of blood vessels but the complete underlying mechanism of vein graft failure is not well understood. Experiments required to understand this phenomenon can be resource and time intensive. In order to augment the existing knowledge and to guide design and interpretation of experiments that are needed to refine our understanding of vein graft growth and remodeling, computational models of vascular growth and remodeling are used to describe and predict the response of vein grafts to changes in hemodynamic loads. Computational models of growth and remodeling have numerous parameters, and even the inputs from experiments have uncertainties associated with them. There is therefore a need for a systematic approach to estimate the parameters included in growth and remodeling models and to evaluate sensitivity of the quantities of interest to parametric variations.
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Reports on the topic "Arterial grafts"

1

Danielson, Darren, W. D. Boyd, Lucas Neff, Sterling Humphrey, Leigh Griffiths, and Hilary Gallogly. Pilot Study of the Efficacy of Extracellular Matrix Arterial Interposition Grafts in a Sheep (Ovis aries) Model. Fort Belvoir, VA: Defense Technical Information Center, February 2014. http://dx.doi.org/10.21236/ada608132.

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2

Liao, Guang-zhi, Ting Liu, Yi-ming Li, Lin Bai, Yu-yang Ye, Xue-feng Chen, and Yong Peng. Total Arterial Revascularization in Diabetic Patients Undergoing Coronary Artery Bypass Graft Surgery: A Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2022. http://dx.doi.org/10.37766/inplasy2022.12.0003.

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3

Danielson, Daren, Lucas P. Neff, Sterling Humphrey, and W. D. Boyd. Pilot Study of the Efficacy of Extracellular Matrix Arterio-Venous Bypass Grafts in a Sheep (Ovis aries) Model. Fort Belvoir, VA: Defense Technical Information Center, December 2013. http://dx.doi.org/10.21236/ada608131.

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4

Kanner, Joseph, Edwin Frankel, Stella Harel, and Bruce German. Grapes, Wines and By-products as Potential Sources of Antioxidants. United States Department of Agriculture, January 1995. http://dx.doi.org/10.32747/1995.7568767.bard.

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Several grape varieties and red wines were found to contain large concentration of phenolic compounds which work as antioxidant in-vitro and in-vivo. Wastes from wine production contain antioxidants in large amounts, between 2-6% on dry material basis. Red wines but also white wines were found to prevent lipid peroxidation of turkey muscle tissues stored at 5oC. The antioxidant reaction of flavonoids found in red wines against lipid peroxidation were found to depend on the structure of the molecule. Red wine flavonoids containing an orthodihydroxy structure around the B ring were found highly active against LDL and membrane lipid peroxidation. The antioxidant activity of red wine polyphenols were also found to be dependent on the catalyzer used. In the presence of H2O2-activated myoglobin, the inhibition efficiency was malvidin 3-glucoside>catechin>malvidin>resveratol. However, in the presence of an iron redox cycle catalyzer, the order of effectiveness was resveratol>malvidin 3-glucoside = malvidin>catechin. Differences in protein binding were found to affect antioxidant activity in inhibiting LDL oxidation. A model protein such as BSA, was investigated on the antioxidant activity of phenolic compounds, grape extracts, and red wines in a lecithin-liposome model system. Ferulic acid followed by malvidin and rutin were the most efficient in inhibiting both lipid and protein oxidation. Catechin, a flavonal found in red-wines in relatively high concentration was found to inhibit myoglobin catalyzed linoleate membrane lipid peroxidation at a relatively very low concentration. This effect was studied by the determination of the by-products generated from linoleate during oxidation. The study showed that hydroperoxides are catalytically broken down, not to an alcohol but most probably to a non-radical adduct. The ability of wine-phenolics to reduce iron and from complexes with metals were also demonstrated. Low concentration of wine phenolics were found to inhibit lipoxygenase type II activity. An attempt to understand the bioavailability in humans of antocyanins from red wine showed that two antocyanins from red wine were found unchanged in human urine. Other antocyanins seems to undergo molecular modification. In hypercholesterolemic hamsters, aortic lipid deposition was significantly less in animals fed diets supplemented with either catechin or vitamin E. The rate of LDL accumulation in the carotid arteries was also significantly lower in the catechin and vitamin E animal groups. These results suggested a novel mechanism by which wine phenolics are associated with decreased risk of coronary heart diseases. This study proves in part our hypothesis that the "French Paradox" could be explained by the action of the antioxidant effects of phenolic compounds found at high concentration in red wines. The results of this study argue that it is in the interest of public health to increase the consumption of dietary plant falvonoids. Our results and these from others, show that the consumption of red wine or plant derived polyphenolics can change the antioxidant tone of animal and human plasma and its isolated components towards oxidative reactions. However, we need more research to better understand bioavailability and the mechanism of how polyphenolics affect health and disease.
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