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1
Mardikantoro, Hari Bakti. "PEMERTAHANAN BAHASA JAWA DALAM PERTUNJUKAN KESENIAN TRADISONAL DI JAWA TENGAH." LITERA 15, no. 2 (November 29, 2016): 269–80. http://dx.doi.org/10.21831/ltr.v15i2.11828.
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PEMERTAHANAN BAHASA JAWADALAM PERTUNJUKAN KESENIAN TRADISONAL DI JAWA TENGAHHari Bakti MardikantoroFBS Universitas Negeri Semarangemail: haribaktim@mail.unnes.ac,idAbstrakTujuan penelitian ini adalah menentukan bentuk pemertahanan bahasa Jawa danmendeskripsikan faktor sosial budaya yang mempengaruhi pemertahanan bahasa Jawadalam pertunjukan kesenian tradisional di Jawa Tengah. Data dalam penelitian ini dijaringdengan menggunakan metode simak. Analisis data dilakukan melalui dua prosedur,yaitu (1) analisis selama proses pengumpulan data dan (2) analisis setelah pengumpulandata. Hasil penelitian menunjukkan bahwa bentuk pemertahanan bahasa Jawa dalampertunjukkan kesenian tradisional di Jawa Tengah meliputi bentuk prakata, tembang, doa,dan pantun. Faktor penyebab pemertahanan bahasa Jawa dalam pertunjukkan keseniantradisonal di Jawa Tengah yakni upaya menjunjung tinggi budaya Jawa, daerah tempattinggal/pertunjukan, keselarasann dengan gerak/tari dan musik/gamelan.Kata kunci: pemertahanan bahasa Jawa, pertunjukan kesenian tradisionalJAVANESE LANGUAGE MAINTENANCEIN TRADITIONAL ART PERFORMANCES IN CENTRAL JAVAAbstractThis study aims to find out forms of the Javanese language maintenance and to describesocio-cultural factors affecting it in traditional art performances in Central Java. The datawere collected through observations. The data analysis procedureincluded (1) the analysisduring thedata collectionprocess and (2) the analysis after the data collection. The resultsof the study reveal that the forms of the Javanese language maintenance includeforewords,songs, prayers, and quatrains. Meanwhile, the factors affecting the the Javanese languagemaintenance in traditional art performances in Central Java include efforts to uphold theJavanese culture, areas of residence/performance, and harmony with movements/dancesand music/gamelan.Keywords: Javanese language maintenance, traditional art performances
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Shahin, M. Y., James A. Crovetti, and Kurt A. Keifer. "Assessing Impact of Bus Traffic on Pavement Maintenance Costs: City of Los Angeles." Transportation Research Record: Journal of the Transportation Research Board 1853, no. 1 (January 2003): 29–36. http://dx.doi.org/10.3141/1853-04.
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Engineers for the city of Los Angeles have observed that lanes carrying Mass Transit Authority (MTA) bus traffic deteriorate at a faster rate than similar lanes without bus traffic. The increased rate of deterioration results in greater maintenance costs in these lanes. To properly apportion the increased maintenance costs, city engineers need an objective method for quantifying the impact of MTA bus traffic. Multiple evaluation techniques are presented that may be used to quantify the effect of buses in terms of increased deterioration rates and greater rehabilitation costs. State-of-the-art techniques that use the results of deflection testing and pavement condition surveys are presented. Data collection procedures, methods for condition and structural analyses, and life-cycle costing procedures are provided. A case study that uses data collected from the city is presented. This study indicates an average yearly additional maintenance cost of $800 per lane-mile caused by MTA bus traffic, excluding associated costs for curb and gutter or maintenance hole adjustments.
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Winkler, S., M. Zessner, E. Saracevic, and N. Fleischmann. "Intelligent monitoring networks – transformation of data into information for water management." Water Science and Technology 58, no. 2 (August 1, 2008): 317–22. http://dx.doi.org/10.2166/wst.2008.672.
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The EU-WFD requires certain monitoring tasks, which yet cannot be fulfilled by automated monitoring devices. Nevertheless, the technical progress of recent years allows monitoring station designs, which enable long-term field application under reasonable maintenance demand. State-of-the-art monitoring stations allow the setup and operation of intelligent monitoring networks, which deliver quality proved and utilisable information to the end-user as opposed to a collection of time-series. Based on a full-scale example monitoring station design, long-term observations and possible ways of (automated) data interpretation are discussed.
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Wang, Rui, Shi Ying, and Xiangyang Jia. "Log Data Modeling and Acquisition in Supporting SaaS Software Performance Issue Diagnosis." International Journal of Software Engineering and Knowledge Engineering 29, no. 09 (September 2019): 1245–77. http://dx.doi.org/10.1142/s0218194019500396.
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Data logging is helpful for the operation and maintenance manager of SaaS-based solutions to diagnose performance issues. However, long-running SaaS software may generate huge amounts of log data which is difficult to analyze, and it lacks a systematic approach to collect the running log and lacks a unified data structure to normalize the performance-related data. All these threaten the timeliness of SaaS performance issue diagnosis. In this paper, we propose an architecture for log collection and analysis to support the assessment of performance and diagnosis of performance issues of SaaS-based application in cloud computing. The architecture has the three-tier structure and includes a pivot data model to integrate heterogeneous log. The two high-level metrics in the model of Average Response Time (ART) and Request Timeout Rate (RTR) are calculated by statistical measurement and the lower-level metrics are monitored in real-time. Operation and maintenance managers can evaluate the performance of SaaS software based on the high-level metrics, then timely locate the issues from the low-level metrics and take appropriate measures. Thereupon, this study presents the general-purpose technique for the architecture to support real-time big log data collection, access, computation, storage. The proposal has been implemented and validated in a case study.
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Kinanti, Lintang Anis Bena. "Formulating Strategies to Develop Jember Historical Tourism Marketing." International Journal of Scientific Research and Management 8, no. 05 (May 12, 2020): 1781–88. http://dx.doi.org/10.18535/ijsrm/v8i05.em04.
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Jember has a long history since prehistoric times, and is evidenced by the diversity of relics from prehistoric times to the colonial period. Historical heritage objects become important regional assets that can generate profits and have a significant effect on economic development. One idea that can be initiated is the presence of an ancient museum. Because of that, an effective marketing strategy is needed to increase the people's visit to the museum and other historical tourism. This study aims to explore how the condition of ancient sites and objects in Jember, explore how the potential of building a museum as a location for storing ancient objects in Jember, and formulating marketing strategies on historical tourism and museums as part of Jember tourism programs. This research adheres to the positivist paradigm using qualitative research methods, using a case study approach by exploring the condition of ancient objects in the Jember area in detail. The results showed that the collection of ancient objects from Jember's history varied greatly with a total of more than 600. A number of collections have been placed in the Antiquities Collection Room, with very limited maintenance, and the room conditions that are not yet representative. For this reason, museum is an alternative solution as a place to store ancient art collection, as well as a part of historical tourism in Jember. The formulation of marketing strategy departs from the concept of SWOT Analysis which is then synergized with the concept of Tourism Marketing Mix.
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Kinanti, Lintang Anis Bena, Dr. Bambang Irawan, M.Si., and Dr. Novi Puspitasari, S.E., M.M. "Strategies Model of Jember Historical Tourism Marketing." International Journal of Scientific Research and Management 8, no. 12 (December 27, 2020): 2058–68. http://dx.doi.org/10.18535/ijsrm/v8i12.em06.
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Jember has a long history since prehistoric times, and is evidenced by the diversity of relics from prehistoric times to the colonial period. Historical heritage objects become important regional assets that can generate profits and have a significant effect on economic development. One idea that can be initiated is the presence of an ancient museum. Because of that, an effective marketing strategy is needed to increase the people's visit to the museum and other historical tourism. This study aims to explore how the condition of ancient sites and objects in Jember, explore how the potential of building a museum as a location for storing ancient objects in Jember, and formulating marketing strategies on historical tourism and museums as part of Jember tourism programs. This research adheres to the positivist paradigm using qualitative research methods, using a case study approach by exploring the condition of ancient objects in the Jember area in detail. The results showed that the collection of ancient objects from Jember's history varied greatly with a total of more than 600. A number of collections have been placed in the Antiquities Collection Room, with very limited maintenance, and the room conditions that are not yet representative. For this reason, museum is an alternative solution as a place to store ancient art collection, as well as a part of historical tourism in Jember. The formulation of marketing strategy departs from the concept of SWOT Analysis which is then synergized with the concept of Tourism Marketing Mix.
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Ikhsan, Muhammad, Hamdil Khaliesh, and Irwin Irwin. "PADEPOKAN SENI DAN BUDAYA MELAYU KALIMANTAN BARAT." JMARS: Jurnal Mosaik Arsitektur 9, no. 1 (February 17, 2021): 184. http://dx.doi.org/10.26418/jmars.v9i1.44986.
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Pontianak City has the potential for training and development of Malay cultural arts. The arts in West Kalimantan generally include dance, music, theater (folklore) and handicrafts. Special events in West Kalimantan will be the culmination of these arts and cultural performances, namely through festivals. This art can be used as a mainstay to face the ASEAN Economic Community. The final project of the Malay Art and Culture Hermitage of West Kalimantan aims to produce a special building design for Malay art and culture with the scope of cultural arts education, recreation, and tourism that can attract public interest. Design boundaries include the arts of music, dance, theater, crafts and cooking in West Kalimantan. The design method of the Malay Art and Culture Hermitage of West Kalimantan was carried out in several stages, namely ideas, data collection, identification, analysis, synthesis, and design development. The concept used in the design is based on the Facilities and Infrastructure Course and Training Institute Standards in 2017. Design analysis produces three functions, namely primary (education), secondary (administration, exhibition, performance) and tertiary (maintenance) functions. The result is that these three functions are combined in one into nine main buildings with a centralized organizational pattern of space, circular circulation, facades, and forms with Malay characteristics.
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Carrillo, Eduardo, and Maricarmen Sequera. "PERSONAL DATA IN THE SOCIAL SECURITY INSTITUTE." Law, State and Telecommunications Review 12, no. 2 (October 13, 2020): 14–37. http://dx.doi.org/10.26512/lstr.v12i2.34689.
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Purpose ”“ The research aims to observe and describe the legal framework and implementation practices of personal databases management in the Social Security Institute (IPS), the most important public social insurance system in Paraguay.
Methodology ”“ The research is exploratory, consisting on both substantive and procedural law analysis of health information storage regulations and its compliance. Also, interview to private companies, the public sector and one qualified worker insured by IPS are conducted to better understand collection, storage and maintenance of health records databases.
Findings ”“ Research indicates evidence that biometric data storage of insurers does not have adequate regulation for its protection. It also shows evidence that private companies don’t deliver by default medical records to workers, as well as potential access to these records by administrative personal. Evidence also signals that clinics performing medical examinations request more sensitive information than required by law. Research limitations It is identified that a broader private company sample could be of use to better understand workers health record collection. Also, third party auditing IPS IT systems could be of use to further understand information management practices and vulnerabilities.
Practical Implications ”“ A series of discretional practices are identified, signaling regulatory standardization urgency for all actors. A comprehensive Protection of Personal Data Act is needed.
Originality ”“ No comprehensive research targeting the IPS system and its health personal data management processes is identified. The research is considered an initial contribution to the state of the art on the subject and specially to biometric collection and storage.
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Levy, Elliot B., Maria I. Fiel, Stanley R. Hamilton, David E. Kleiner, Shannon J. McCall, Peter Schirmacher, William Travis, et al. "State of the Art: Toward Improving Outcomes of Lung and Liver Tumor Biopsies in Clinical Trials—A Multidisciplinary Approach." Journal of Clinical Oncology 38, no. 14 (May 10, 2020): 1633–40. http://dx.doi.org/10.1200/jco.19.02322.
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PURPOSE National Cancer Institute (NCI)–sponsored clinical trial network studies frequently require biopsy specimens for pharmacodynamic and molecular biomarker analyses, including paired pre- and post-treatment samples. The purpose of this meeting of NCI-sponsored investigators was to identify local institutional standard procedures found to ensure quantitative and qualitative specimen adequacy. METHODS NCI convened a conference on best biopsy practices, focusing on the clinical research community. Topics discussed were (1) criteria for specimen adequacy in the personalized medicine era, (2) team-based approaches to ensure specimen adequacy and quality control, and (3) risk considerations relevant to academic and community practitioners and their patients. RESULTS AND RECOMMENDATIONS Key recommendations from the convened consensus panel included (1) establishment of infrastructure for multidisciplinary biopsy teams with a formalized information capture process, (2) maintenance of standard operating procedures with regular team review, (3) optimization of tissue collection and yield methodology, (4) incorporation of needle aspiration and other newer techniques, and (5) commitment of stakeholders to use of guideline documents to increase awareness of best biopsy practices, with the goal of universally improving tumor biopsy practices.
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Puspitasari, Yola, Muhammad Zid, and Ode Sofyan Hardi. "The Implementation of Teacher Strategies in Maintaining Sundanese Culture in the Senior High School Region I West Java." Jurnal Geografi Gea 21, no. 1 (May 1, 2021): 50–57. http://dx.doi.org/10.17509/gea.v21i1.32059.
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This research aims to analyze the implementation of teacher strategies in maintaining Sundanese Culture in West Java, at Senior High Schools in Region I West Java. The research method used was descriptive-qualitative with literature study. Data collection techniques were done through interviews, documentation, and examining secondary data as complementary data. The results showed that territory that were further away from the Priangan/Bandung area such as Depok City, and parts of Bogor Regency which bordered by Banten and Depok, has cultural acculturation and it was difficult to maintain Sundanese language, so that this region places great emphasis on Sundanese arts and traditional clothes. To instill a love “nyaah” or love of Sundanese culture, namely by implementing Sundanese art activity program strategies and competitions on Sundanese culture in schools by adjusting the language used in the area, namely Indonesian with the Betawinese dialect. Meanwhile for territory of closer Priangan/Bandung like the Sukabumi City, Bogor City, Cianjur Regency, Sukabumi Regency, and parts of Bogor Regency which border Cianjur-Sukabumi, there is no difficulty that the maintenance of Sundanese culture, because the majority of students in this region is the original Sundanese people. Yet these areas implement strategy in the use of language in accordance undak-usuk or origin of Sundanese language through a lesson and outside of a lesson, and focused on aspects art and Sundanese traditional clothes, with an implement strategy through activity program pasanggirikasundaan (competition on Sundanese) and art Sundanese at school.
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Fitriani, Fitriani, and Yurni Suasti. "Participation of Educational Institutions in Supporting Halal Tourism Destination Program through Development of Local Culture in East Lombok Regency." Sumatra Journal of Disaster, Geography and Geography Education 2, no. 1 (June 6, 2018): 156. http://dx.doi.org/10.24036/sjdgge.v2i1.117.
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The purpose of this study is to obtain information about the participation of educational institutions in supporting Halal Tourism destination through development of local culture. This study uses qualitative descriptive approach by using observation, interview and questionnaire in data collection. Subjects to be studied in this study are head of education department, principal (SMAN 1 Rujukan Selong) and random people in the community. Sample is determined by purposive sampling technique to select school and proportional random sampling technique to select respondent. Study finding obtained from formal institutions: 1) good example from teacher as a model in character education, 2) curriculum that contain Halal Tourism, 3) contribution in improvement and maintenance of tourism facilities and infrastructures in location of tourism attractions, 4) held a parade on Islam holiday (PHBI) and Islamic art contest. Meanwhile, non-formal participations are: 1) construction of religious facilities, 2) selling halal food products in area of tourist attraction, 3) selling Islamic souvenirs.
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Ince, E. Sinem, Franz Barthelmes, Sven Reißland, Kirsten Elger, Christoph Förste, Frank Flechtner, and Harald Schuh. "ICGEM – 15 years of successful collection and distribution of global gravitational models, associated services, and future plans." Earth System Science Data 11, no. 2 (May 15, 2019): 647–74. http://dx.doi.org/10.5194/essd-11-647-2019.
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Abstract. The International Centre for Global Earth Models (ICGEM, http://icgem.gfz-potsdam.de/, last access: 6 May 2019) hosted at the GFZ German Research Centre for Geosciences (GFZ) is one of the five services coordinated by the International Gravity Field Service (IGFS) of the International Association of Geodesy (IAG). The goal of the ICGEM service is to provide the scientific community with a state-of-the-art archive of static and temporal global gravity field models of the Earth, and develop and operate interactive calculation and visualization services of gravity field functionals on user-defined grids or at a list of particular points via its website. ICGEM offers the largest collection of global gravity field models, including those from the 1960s to the 1990s, as well as the most recent ones, which have been developed using data from dedicated satellite gravity missions, CHAMP, GRACE, GOCE, advanced processing methodologies, and additional data sources such as satellite altimetry and terrestrial gravity. The global gravity field models have been collected from different institutions at international level and after a validation process made publicly available in a standardized format with DOI numbers assigned through GFZ Data Services. The development and maintenance of such a unique platform is crucial for the scientific community in geodesy, geophysics, oceanography, and climate research. In this article, we present the development history and future plans of ICGEM and its current products and essential services. We present the ICGEM's data by means of Earth's static, temporal, and topographic gravity field models as well as the gravity field models of other celestial bodies together with examples produced by the ICGEM's calculation and 3-D visualization services and give an insight into how the ICGEM service can additionally contribute to the needs of research and society.
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Di Prima, Simone, Mirko Castellini, Mario Pirastru, and Saskia Keesstra. "Soil Water Conservation: Dynamics and Impact." Water 10, no. 7 (July 18, 2018): 952. http://dx.doi.org/10.3390/w10070952.
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Human needs like food and clean water are directly related to good maintenance of healthy and productive soils. A good understanding of human impact on the natural environment is therefore necessary to preserve and manage soil and water resources. This knowledge is particularly important in semi-arid and arid regions, where the increasing demands on limited water supplies require urgent efforts to improve water quality and water use efficiency. It is important to keep in mind that both soil and water are limited resources. Thus, wise use of these natural resources is a fundamental prerequisite for the sustainability of human societies. This Special Issue collects 15 original contributions addressing the state of the art of soil and water conservation research. Contributions cover a wide range of topics, including (1) recovery of soil hydraulic properties; (2) erosion risk; (3) novel modeling, monitoring and experimental approaches for soil hydraulic characterization; (4) improvement of crop yields; (5) water availability; and (6) soil salinity. The collection of manuscripts presented in this Special Issue provides more insights into conservation strategies for effective and sustainable soil and water management.
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Shukla, S., C. Y. Yu, J. D. Hardin, and F. H. Jaber. "Wireless Data Acquisition and Control Systems for Agricultural Water Management Projects." HortTechnology 16, no. 4 (January 2006): 595–604. http://dx.doi.org/10.21273/horttech.16.4.0595.
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Continuous monitoring of hydraulic/hydrologic data for managing water for horticultural crops has been a challenge due to factors such as data loss, intensive resource requirements, and complicated setup and operation. The use of state-of-the-art wireless spread spectrum communication technology and wireless data acquisition and control (WDAC) systems for agricultural water management is discussed in this paper. The WDAC technology was applied to a research project where lysimeters were used for water quantity and quality studies for vegetables. Two types of WDAC networks, master–slave and peer-to-peer WDAC networks, are discussed. The WDAC system linked the wireless dataloggers to a network to make real-time data available over the Internet. The use of WDAC made it possible to collect real-time data and control the experiment (e.g., frequency of data collection) remotely through the Internet. The WDAC system for the lysimeter study was compared to a commonly used manual system with regard to potential instrument damage, data loss, ease of data collection and analyses, and total cost of monitoring. The advantages of the WDAC include: reduced equipment losses from natural disasters (e.g., lightning), improved equipment maintenance, reduced data loss from faulty equipment, higher project personnel efficiency, and real-time involvement by a dispersed team. The total cost of the WDAC system ($65,750) was about half that of the manual system ($130,380). The WDAC system was found to be an effective tool for agricultural water management projects.
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Pispidikis, I., E. Tsiliakou, D. Kitsakis, K. Athanasiou, E. Kalogianni, T. Labropoulos, and E. Dimopoulou. "COMBINING METHODOLOGICAL TOOLS FOR THE OPTIMUM 3D MODELLING OF NTUA CAMPUS." ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences IV-4/W6 (September 12, 2018): 57–63. http://dx.doi.org/10.5194/isprs-annals-iv-4-w6-57-2018.
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<p><strong>Abstract.</strong> Rapid urbanisation relates to increased space requirements above and below ground and the development of complex structures. This profound need attracted increasing interest for the collection, modelling, management, visualisation and dissemination of 3D objects through various application fields, such as: 3D Cadastre, 3D City Modelling and Building Information Modelling. Contemporary advances in GIS technology, Geo-Web services and computer graphics facilitate the development of such models accompanied by semantic, geometrical and topological information, while the use of international standards enables the communication and interoperability between the systems. The aim of this paper is to combine state-of-the art methodologies and technologies for the development of semantically enriched 3D models for the Campus of the National Technical University of Athens in Greece. The result is a web-based 3D Campus map that integrates these models as Web Services, providing access to management and navigation for the campus area and can also be used for maintenance purposes from the various NTUA Departments. To this end, the database schema has been designed compatible with CityGML, while attention was given to interoperability issues that arise from differently derived 3D models which had to be stored and visualised while retaining their characteristics.</p>
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Jacobs, Marshall Lewis, Jeffrey Phillip Jacobs, Rodney C. G. Franklin, Constantine Mavroudis, Francois Lacour-Gayet, Christo I. Tchervenkov, Hal Walters, et al. "Databases for assessing the outcomes of the treatment of patients with congenital and paediatric cardiac disease – the perspective of cardiac surgery." Cardiology in the Young 18, S2 (December 2008): 101–15. http://dx.doi.org/10.1017/s1047951108002813.
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AbstractThis review includes a brief discussion, from the perspective of cardiac surgeons, of the rationale for creation and maintenance of multi-institutional databases of outcomes of congenital heart surgery, together with a history of the evolution of such databases, a description of the current state of the art, and a discussion of areas for improvement and future expansion of the concept. Five fundamental areas are reviewed: nomenclature, mechanism of data collection and storage, mechanisms for the evaluation and comparison of the complexity of operations and stratification of risk, mechanisms to ensure the completeness and accuracy of the data, and mechanisms for expansion of the current capabilities of databases to include comparison and sharing of data between medical subspecialties. This review briefly describes several European and North American initiatives related to databases for pediatric and congenital cardiac surgery the Congenital Database of The European Association for Cardio-Thoracic Surgery, the Congenital Database of The Society of Thoracic Surgeons, the Pediatric Cardiac Care Consortium, and the Central Cardiac Audit Database in the United Kingdom. Potential means of approaching the ultimate goal of acquisition of long-term follow-up data, and input of this data over the life of the patient, are also considered.
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Carrara, Arnaud, Pasi Kolari, Maarten Op de Beeck, Nicola Arriga, Daniel Berveiller, Sigrid Dengel, Andreas Ibrom, et al. "Radiation measurements at ICOS ecosystem stations." International Agrophysics 32, no. 4 (December 1, 2018): 589–605. http://dx.doi.org/10.1515/intag-2017-0049.
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Abstract Solar radiation is a key driver of energy and carbon fluxes in natural ecosystems. Radiation measurements are essential for interpreting ecosystem scale greenhouse gases and energy fluxes as well as many other observations performed at ecosystem stations of the Integrated Carbon Observation System (ICOS). We describe and explain the relevance of the radiation variables that are monitored continuously at ICOS ecosystem stations and define recommendations to perform these measurements with consistent and comparable accuracy. The measurement methodology and instruments are described including detailed technical specifications. Guidelines for instrumental set up as well as for operation, maintenance and data collection are defined considering both ICOS scientific objectives and practical operational constraints. For measurements of short-wave (solar) and long wave (infrared) radiation components, requirements for the ICOS network are based on available well-defined state-of-the art standards (World Meteorological Organization, International Organization for Standardization). For photosynthetically active radiation measurements, some basic instrumental requirements are based on the performance of commercially available sensors. Since site specific conditions and practical constraints at individual ICOS ecosystem stations may hamper the applicability of standard requirements, we recommend that ICOS develops mid-term coordinated actions to assess the effective level of uncertainties in radiation measurements at the network scale.
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Chen, Peng, Weiliang Zeng, Guizhen Yu, and Yunpeng Wang. "Surrogate Safety Analysis of Pedestrian-Vehicle Conflict at Intersections Using Unmanned Aerial Vehicle Videos." Journal of Advanced Transportation 2017 (2017): 1–12. http://dx.doi.org/10.1155/2017/5202150.
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Conflict analysis using surrogate safety measures (SSMs) has become an efficient approach to investigate safety issues. The state-of-the-art studies largely resort to video images taken from high buildings. However, it suffers from heavy labor work, high cost of maintenance, and even security restrictions. Data collection and processing remains a common challenge to traffic conflict analysis. Unmanned Aerial Systems (UASs) or Unmanned Aerial Vehicles (UAVs), known for easy maneuvering, outstanding flexibility, and low costs, are considered to be a novel aerial sensor. By taking full advantage of the bird’s eye view offered by UAV, this study, as a pioneer work, applied UAV videos for surrogate safety analysis of pedestrian-vehicle conflicts at one urban intersection in Beijing, China. Aerial video sequences for a period of one hour were analyzed. The detection and tracking systems for vehicle and pedestrian trajectory data extraction were developed, respectively. Two SSMs, that is, Postencroachment Time (PET) and Relative Time to Collision (RTTC), were employed to represent how spatially and temporally close the pedestrian-vehicle conflict is to a collision. The results of analysis showed a high exposure of pedestrians to traffic conflict both inside and outside the crosswalk and relatively risking behavior of right-turn vehicles around the corner. The findings demonstrate that UAV can support intersection safety analysis in an accurate and cost-effective way.
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Arroyo Ohori, K., A. Labetski, G. Agugiaro, M. Koeva, and J. Stoter. "PREFACE." ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences IV-4/W6 (September 12, 2018): 1. http://dx.doi.org/10.5194/isprs-annals-iv-4-w6-1-2018.
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<p><strong>Abstract.</strong> The annual 3D GeoInfo Conference aims at bringing together international state-of-the-art research and facilitating dialogue on emerging topics in the field of 3D geoinformation. On the 1st and 2nd of October 2018, the 13th 3D GeoInfo conference was organised at the Delft University of Technology. On this occasion, the topics included 3D data collection and modelling, reconstruction methods for 3D representation, data management for maintenance of 3D geoinformation or 3D data, applications of 3D geoinformation, and visualisation.</p><p>This volume of the ISPRS Annals contains the 12 full papers that received the most positive double-blind peer reviews from the Scientific Committee of the 3D GeoInfo Conference. The other 33 presented papers are published in the ISPRS Archives.</p><p>We hope that the papers in this special issue will inspire decision-makers, academics, engineers, computer scientists, land surveyors, urban planners, and students interested in the 3D geoinformation domain. We would like to thank all the authors, the reviewers, and the organising committee for their valuable contribution towards this publication.</p><p>We would like to acknowledge that we have received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 677312 UMnD: Urban modelling in higher dimensions).</p>
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Kundu, Nidhi, Geeta Rani, Vijaypal Singh Dhaka, Kalpit Gupta, Siddaiah Chandra Nayak, Sahil Verma, Muhammad Fazal Ijaz, and Marcin Woźniak. "IoT and Interpretable Machine Learning Based Framework for Disease Prediction in Pearl Millet." Sensors 21, no. 16 (August 9, 2021): 5386. http://dx.doi.org/10.3390/s21165386.
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Decrease in crop yield and degradation in product quality due to plant diseases such as rust and blast in pearl millet is the cause of concern for farmers and the agriculture industry. The stipulation of expert advice for disease identification is also a challenge for the farmers. The traditional techniques adopted for plant disease detection require more human intervention, are unhandy for farmers, and have a high cost of deployment, operation, and maintenance. Therefore, there is a requirement for automating plant disease detection and classification. Deep learning and IoT-based solutions are proposed in the literature for plant disease detection and classification. However, there is a huge scope to develop low-cost systems by integrating these techniques for data collection, feature visualization, and disease detection. This research aims to develop the ‘Automatic and Intelligent Data Collector and Classifier’ framework by integrating IoT and deep learning. The framework automatically collects the imagery and parametric data from the pearl millet farmland at ICAR, Mysore, India. It automatically sends the collected data to the cloud server and the Raspberry Pi. The ‘Custom-Net’ model designed as a part of this research is deployed on the cloud server. It collaborates with the Raspberry Pi to precisely predict the blast and rust diseases in pearl millet. Moreover, the Grad-CAM is employed to visualize the features extracted by the ‘Custom-Net’. Furthermore, the impact of transfer learning on the ‘Custom-Net’ and state-of-the-art models viz. Inception ResNet-V2, Inception-V3, ResNet-50, VGG-16, and VGG-19 is shown in this manuscript. Based on the experimental results, and features visualization by Grad-CAM, it is observed that the ‘Custom-Net’ extracts the relevant features and the transfer learning improves the extraction of relevant features. Additionally, the ‘Custom-Net’ model reports a classification accuracy of 98.78% that is equivalent to state-of-the-art models viz. Inception ResNet-V2, Inception-V3, ResNet-50, VGG-16, and VGG-19. Although the classification of ‘Custom-Net’ is comparable to state-of-the-art models, it is effective in reducing the training time by 86.67%. It makes the model more suitable for automating disease detection. This proves that the proposed model is effective in providing a low-cost and handy tool for farmers to improve crop yield and product quality.
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Arroyo Ohori, K., A. Labetski, G. Agugiaro, M. Koeva, and J. Stoter. "PREFACE." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-4/W10 (September 12, 2018): 1. http://dx.doi.org/10.5194/isprs-archives-xlii-4-w10-1-2018.
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<p><strong>Abstract.</strong> The annual 3D GeoInfo Conference aims at bringing together international state-of-the-art research and facilitating dialogue on emerging topics in the field of 3D geoinformation. On the 1st and 2nd of October 2018, the 13th 3D GeoInfo conference was organised at the Delft University of Technology. On this occasion, the topics included 3D data collection and modelling, reconstruction methods for 3D representation, data management for maintenance of 3D geoinformation or 3D data, applications of 3D geoinformation, and visualisation.</p><p>This volume of the ISPRS Archives is composed of 9 full papers that received positive double-blind peer reviews, as well as the 24 papers that received positive double-blind reviews as abstracts and were then extended into papers. The 12 full papers with the most positive reviews were instead published in the ISPRS Annals.</p><p> We hope that the papers in this special issue will inspire decision-makers, academics, engineers, computer scientists, land surveyors, urban planners, and students interested in the 3D geoinformation domain. We would like to thank all the authors, the reviewers, and the organising committee for their valuable contribution towards this publication.</p><p> We would like to acknowledge that we have received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 677312 UMnD: Urban modelling in higher dimensions).</p>
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McClure, Robert C., Caroline L. Macumber, Julia L. Skapik, and Anne Marie Smith. "Igniting Harmonized Digital Clinical Quality Measurement through Terminology, CQL, and FHIR." Applied Clinical Informatics 11, no. 01 (January 2020): 023–33. http://dx.doi.org/10.1055/s-0039-3402755.
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Abstract Background Electronic clinical quality measures (eCQMs) seek to quantify the adherence of health care to evidence-based standards. This requires a high level of consistency to reduce the effort of data collection and ensure comparisons are valid. Yet, there is considerable variability in local data capture, in the use of data standards and in implemented documentation processes, so organizations struggle to implement quality measures and extract data reliably for comparison across patients, providers, and systems. Objective In this paper, we discuss opportunities for harmonization within and across eCQMs; specifically, at the level of the measure concept, the logical clauses or phrases, the data elements, and the codes and value sets. Methods The authors, experts in measure development, quality assurance, standards and implementation, reviewed measure structure and content to describe the state of the art for measure analysis and harmonization. Our review resulted in the identification of four measure component levels for harmonization. We provide examples for harmonization of each of the four measure components based on experience with current quality measurement programs including the Centers for Medicare and Medicaid Services eCQM programs. Results In general, there are significant issues with lack of harmonization across measure concepts, logical phrases, and data elements. This magnifies implementation problems, confuses users, and requires more elaborate data mapping and maintenance. Conclusion Comparisons using semantically equivalent data are needed to accurately measure performance and reduce workflow interruptions with the aim of reducing evidence-based care gaps. It comes as no surprise that electronic health record designed for purposes other than quality improvement and used within a fragmented care delivery system would benefit greatly from common data representation, measure harmony, and consistency. We suggest that by enabling measure authors and implementers to deliver consistent electronic quality measure content in four key areas; the industry can improve quality measurement.
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Kazandjian, Dickran, Neha S. Korde, Mark Roschewski, Sham Mailankody, Candis Morrison, Elisabet E. Manasanch, Mary L. Kwok, et al. "Sustained Minimal Residual Disease Negativity in Newly Diagnosed Multiple Myeloma (NDMM) Patients Treated with Carfilzomib (CFZ), Lenalidomide (LEN), and Dexamethasone (DEX) Followed By 2 Years of Lenalidomide Maintenance (CRd-R): Updated Results of a Phase 2 Study." Blood 128, no. 22 (December 2, 2016): 4527. http://dx.doi.org/10.1182/blood.v128.22.4527.4527.
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Abstract Background: State of the art treatment for patients with NDMM involves induction with triplet regimens utilizing newer therapies including combinations of immunomodulatory (IMiD) drugs and proteasome inhibitors (PI) which improve progression-free survival (PFS) over doublet regimens. CFZ is a selective PI that inhibits the chymotrypsin-like activity of the 20S proteasome and has been approved in combination with LEN and DEX for the treatment of patients with relapsed or refractory MM who have received 1-3 lines of therapy. Furthermore, it has been associated with decreased neuropathy and increased clinical benefit over bortezomib-based combinations. This phase 2 study of 45 patients demonstrated that deep and durable responses with CRd-R can be achieved in the NDMM setting (Korde et al. JAMA Onc 2015). Here, we expand on our initial results in assessing minimal residual disease negativity (MRDneg) at complete response (CR) and after 1 and 2 years of LEN maintenance. We also characterize depth of response by age and cytogenetic risk profile. Methods: Treatment-na•ve patients with MM were treated for 8 cycles (28-day cycles) with CFZ 20/36 mg/m2 IV days 1, 2, 8, 9, 15, 16; LEN 25 mg PO days 1-21, and DEX 20/10 mg IV/PO days 1, 2, 8, 9, 15, 16, 22, 23. Transplant eligible patients underwent stem cell collection after ≥4 cycles of CRd and then continued CRd treatment (i.e. by-default-delayed high-dose melphalan with autologous stem cell transplant; HDM-ASCT). After 8 cycles of combination therapy, patients with SD or better received 2 years of LEN 10 mg PO maintenance. The primary objective of the study was to estimate the rate of ³ Grade 3 peripheral neuropathy with secondary objectives of response (ORR), MRDneg, PFS, and response duration (DoR) assessed after every cycle during induction and subsequently after every 90 days of maintenance therapy. Assessment of MRDneg by multi-color flow cytometry (bone marrow aspirate; 10-5 sensitivity) was performed after 8 cycles of induction, and 1 and 2 years of LEN maintenance. Results: Forty-five patients meeting eligibility criteria were enrolled (60% male; median age 60, range 40-89; race: 82% White, 13% Black, 4% Asian; isotypes: 51% IgG kappa, 16% IgG lambda, 13% IgA kappa, 9% IgA lambda, 9% free kappa, and 4% free lambda). The proportion of patients who obtained a complete response (CR) with MRDneg after 8 cycles of induction, 1 year of maintenance and 2 years of maintenance was 44%, 54% and 46%, respectively (Table 1). These deep responses of MRDneg CR were observed regardless of age group or cytogenetic-based risk profile (Table 2). ORR was 98% with a DoR at 48 months of 81%. PFS at 48 months was 82% and overall survival at 58 months was 86% with a median duration of follow-up of 31 months. Toxicities, in general, were manageable, with Grade 3-4 events occurring in >1 patient including lymphopenia (69%), neutropenia (27%), thrombocytopenia (20%) anemia (18%), hypophosphatemia (18%), leukopenia (16%), maculo-papular rash (13%), alanine aminotransferase elevation (11%), fatigue (9%), dyspnea (9%), hyponatremia 7%, thromboembolism (7%), lung infection (4%), hypoalbuminemia (4%). Serious adverse events included thromboembolism (13%), dyspnea (9%), anemia (7%), lung infection (4%), thrombocytopenia (4%), hyponatremia (4%), and pleural effusion (4%). Conclusions: Upfront treatment of NDMM with modern, highly efficacious CRd-R therapy with by-default-delayed HDM-ASCT led to high rates of sustained MRDneg CR (as defined by the updated 2016 IMWG response criteria) which is correlated with longer PFS and OS. Clinically important, these deep responses were observed regardless of the age of patients or cytogenetic risk. Our findings stress the importance of utilizing highly efficacious triplet-based regimens for the treatment of patients with NDMM regardless of age or cytogenetic risk. Updated results will be presented at the Annual Meeting. Disclosures Korde: Medscape: Honoraria. Bhutani:Prothena: Research Funding; Takeda Oncology: Research Funding, Speakers Bureau; Bristol-Myers Squibb: Speakers Bureau; Onyx, an Amgen subsidiary: Speakers Bureau. Landgren:Takeda: Honoraria; Amgen: Honoraria, Research Funding; Celgene: Honoraria, Research Funding; Medscape Myeloma Program: Honoraria; Merck: Honoraria; BMS: Honoraria.
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Mazurek, Justyna, Dorota Szcześniak, Elżbieta Trypka, Katarzyna Małgorzata Lion, Renata Wallner, and Joanna Rymaszewska. "Needs of Older People Attending Day Care Centres in Poland." Healthcare 8, no. 3 (August 29, 2020): 310. http://dx.doi.org/10.3390/healthcare8030310.
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Introduction: Day care centres (DCC) aim to support older adults living in their own homes by providing a variety of activities to promote the independence of those people and reduce the caregiver’s burden. In Poland, there are no standards for providing this form of care. The provided care is delivered by different organisations, and there is a lack of quality control in the majority of places. Regrettably, in Poland, there is a paucity of research on the holistic needs of the elderly attending DCC. Aim of this study: This is the first study which has aimed to identify the Polish day care centres attendees’ needs to ensure that the increasing number of older people receive the best possible care, and as a part of the quality improvement process for recommendation development of the new day care services model in Poland within the ‘Homely Marina’ project. Methods and Materials: A representative sample (n = 269) was randomly selected from day care centres attendees (estimated as 10,688) in Poland. An anonymous survey for the assessment of needs was developed by the authors. Results: The respondents assessed the level of provided services as very good or good. Best rated services included meals, supportive and welfare services (occupational therapy, music therapy, art therapy, cognitive training). Almost half of the participants indicated the need for company as the main reason to attend a DCC. This research reveals a lack of support with regard to additional staff: e.g., a nurse. Conclusions: In Poland, the services offered in DCC should focus on social isolation and sense of loneliness prevention, and maintenance of social activity of the elderly. The presented analysis of needs in Polish day care centres suggests a need for changes which may improve the quality of services. There is a great need to find a balance between home-based care and in-patient care, using better integration of available services and strengthening support for informal caregivers. Robust research with a collection of meaningful outcomes is required to ensure that in Poland, the increasing number of older people is enabled to access high-quality day care service provision.
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Seyr, Helene, and Michael Muskulus. "Decision Support Models for Operations and Maintenance for Offshore Wind Farms: A Review." Applied Sciences 9, no. 2 (January 14, 2019): 278. http://dx.doi.org/10.3390/app9020278.
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This paper reviews the state of the art in offshore wind farm operations and maintenance with a focus on decision support models for the scheduling of maintenance. Factors influential to maintenance planning are collected from the literature and their inclusion in state-of-the-art models is discussed. Methods for modeling and optimization are presented. The methods currently used and possible alternatives are discussed. The existing models are already able to aid the decision-making process. They can be improved by applying more advanced mathematical methods, including uncertainties in the input, regarding more of the influential factors, and by collecting, analyzing, and subsequently using more accurate data.
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Grier, David V., Arthur F. Hawnn, John M. Lane, and Shilpa Patel. "Harbor Maintenance Trust Fund." Transportation Research Record: Journal of the Transportation Research Board 1909, no. 1 (January 2005): 54–61. http://dx.doi.org/10.1177/0361198105190900108.
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The status and the performance of the Harbor Maintenance Trust Fund (HMTF) are evaluated. The harbor maintenance tax (HMT) and HMTF were established by Title XIV of the Water Resources Development Act of 1986. The HMT is applied as a 0.125% ad valorem fee on the value of commercial cargo loaded or unloaded on vessels using federally maintained harbor projects. The HMTF is authorized to be used to recover 100% of the U.S. Army Corps of Engineers eligible operation and maintenance (O&M) expenditures for commercial navigation, along with 100% of the O&M cost of the St. Lawrence Seaway by the St. Lawrence Seaway Development Corporation, certain costs of the National Oceanic and Atmospheric Administration, and costs to administer the HMTF. The U.S. Supreme Court found that the HMT violated the export clause of the U.S. Constitution; as a result, the U.S. Customs Service halted HMT collections on U.S. exports in fiscal year 1998. However, the revenue stream from HMT collections on imports, domestic shipments, passengers, foreign trade zone cargo, and interest earnings should be sufficient to recover eligible expenditures for the foreseeable future.
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Simpson, Amy L., Gonzalo R. J. Rada, Beth Visintine, and Jonathan Groeger. "Sampling to Evaluate Performance on the Interstate Highway System." Transportation Research Record: Journal of the Transportation Research Board 2639, no. 1 (January 2017): 20–27. http://dx.doi.org/10.3141/2639-03.
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The Moving Ahead for Progress in the 21st Century Act highlighted the need to monitor the performance of pavement sections over time. An important aspect of performance monitoring is collecting a statistically significant sample of the network so conclusions can be made about changes in performance and types of maintenance and rehabilitation needed for maintaining these assets. This paper reviews the sampling requirements on the Interstate highway system to draw accurate conclusions about the network. Specifically, the paper answers the following questions: Is two-way data collection necessary? Do data have to be collected in more than one lane in a direction? What is the optimum reporting length? For what percentage of the network should data be collected? Should data be collected annually?
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Shujuan, Dai. "Towards the 21st century: the development of the Reference Library of the Chinese Academy of Arts." Art Libraries Journal 22, no. 1 (1997): 4–8. http://dx.doi.org/10.1017/s0307472200010245.
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The Reference Library of the Chinese Academy of Arts (RLCAA) has identified the maintenance and development of its rich collections as its primary objective, which it pursues not merely by acquiring published materials but also, for example, by making recordings of musical and dramatic performances. But also, the RLCAA is committed to promoting and facilitating the use of its collections, and is consciously moving away from a passive custodial role to the active provision of services to users. In order to serve their users better, libraries must end their isolation and join together in networks; a new building at the Chinese Academy of Arts is to become the national centre for art information and library services, and this development also challenges the Academy to co-ordinate its several resource centres more effectively. Staff at the RLCAA have already created an art thesaurus, and are currently working on a bibliography of Chinese artists which it is hoped will be the first of several online databases covering different branches of the arts in China.
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Reed, Derek D., Daniel M. Fienup, James K. Luiselli, and Gary M. Pace. "Performance Improvement in Behavioral Health Care: Collateral Effects of Planned Treatment Integrity Observations as an Applied Example of Schedule-Induced Responding." Behavior Modification 34, no. 5 (September 2010): 367–85. http://dx.doi.org/10.1177/0145445510383524.
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With rising interest in the role of treatment integrity on student outcomes, research has primarily focused on isolating the techniques and procedures necessary to improve staff’s acquisition and maintenance of adequate levels of integrity. Despite increasing numbers of publications on this topic, there has been little discussion of the variables surrounding the collection of integrity data. Using an archived database of logged integrity observations at a residential school for children with brain injury, the authors sought to examine the degree to which integrity data collection conformed to best practices of behavioral assessment with respect to temporal sequencing. Moreover, due to the agency’s goal of collecting integrity on each student per month, the authors sought to examine whether the sequencing of integrity observations scalloped similarly to responding on conjunctive fixedinterval—fixed-ratio schedules. Results indicated that a majority of the staff exhibited some form of scalloping in their collection of integrity data. This article discusses possible sources of stimulus control and the potential for reactivity on the part of the teachers being observed when integrity observations are conducted in scalloped patterns. The authors conclude with a discussion on possible procedures to support the distributed collection of integrity data in applied setting.
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Doustmohammadi, Mehrnaz, and Michael Anderson. "A Bayesian Regression Model for Estimating Average Daily Traffic Volumes for Low Volume Roadways." International Journal of Statistics and Probability 8, no. 1 (December 28, 2018): 143. http://dx.doi.org/10.5539/ijsp.v8n1p143.
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Common Average Daily Traffic (ADT) estimation models use Linear Regression and a collection of socio-economic and roadway variables. While linear regression is widely understood, it is not always optimal for developing prediction models as the regression techniques don’t have the ability to account for data distributions, or variability of the point estimates. To overcome this limitation, this paper presents a study that utilizes a Bayesian Regression model to develop a model to estimate ADT values for low volume roadways. The need for ADT estimates is critical as roadway traffic counts are the backbone of maintenance, safety and construction designs. While significant investment is made in collecting ADT values for higher functionally classified and high volume roadways, low volume roadways are often neglected in the traffic count program due to budget limitations and the misguided notion that there is limited return on investment in counting these facilities. This research developed a technique to estimate ADT for local roads in Alabama incorporating variables used in previous studies and a Bayesian Regression model. The final Bayesian Regression model relies on four independent variables: number of households in the area, employment in the area, population to job ratio and access to major roads. The model was used to generate ADT estimates on low-volume rural, local roads for 12 counties in Alabama. The paper concludes that the model can be used to predict the ADT for low-volumes roadways in Alabama for future applications.
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EVELYN, DOUGLAS E. "The Smithsonian's National Museum of the American Indian: An International Institution of Living Cultures." Public Historian 28, no. 2 (January 1, 2006): 51–56. http://dx.doi.org/10.1525/tph.2006.28.2.51.
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The mission of the Smithsonian Institution's National Museum of the American Indian is to affirm to Native communities and the non-Native public the historical and contemporary culture and cultural achievements of the Natives of the Western Hemisphere by advancing, in consultations, collaboration and cooperation with them, a knowledge and understanding of their cultures, including art, history and language, and by recognizing the Museum's special responsibility, through innovative public programming, research and collections, to protect, support and enhance the development, maintenance and perpetuation of Native culture and community. Adopted 1990.
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Kanavos, Panos, John Yfantopoulos, Christina Vandoros, and Costantina Politis. "The economics of blood: Gift of life or a commodity?" International Journal of Technology Assessment in Health Care 22, no. 3 (July 2006): 338–43. http://dx.doi.org/10.1017/s0266462306051233.
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Objectives:To calculate the costs of blood collection, testing, storage, and transfusion in Greece.Methods:Costing information was collected from two large public hospitals, in Athens and Crete, that also act as blood banks. Given that private health care accounts for 40 percent of total health spending, the same costs were also considered in a private setting by collecting key reagent cost data from a leading private hospital in Athens. Mainly direct costs were considered (advertising campaigns, personnel, storage and maintenance, reagent costs, transportation costs from blood bank to end-use hospitals, and cross-matching and transfusion costs in receiving hospitals) and some indirect costs (opportunity cost of blood donorship).Results:Captive donorship accounts for over 50 percent of the national blood supply. A unit of blood transfused would cost between €294.83 and €339.83 in public hospitals and could reach €413.93 in a private facility. This figure may be an underestimate, as it excludes opportunity costs of blood transfusion for patients and the healthcare system.Conclusions:Blood has a significant cost to the health system. Policy makers and practitioners should encourage its rational use, build on current policies to further improve collection and distribution, encourage further volunteer donorship in Greece, and also consider alternatives to blood where the possibility exists.
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Kazandjian, Dickran, Neha Korde, Sham Mailankody, Yong Zhang, Jennifer Hsu, Elizabeth Hill, Candis Morrison, et al. "A Phase 2 Study of Carfilzomib, Lenalidomide, and Dexamethasone with Lenalidomide Maintenance (KRd-r) in Newly Diagnosed Multiple Myeloma (NDMM): Sustained Long Term Deep Remissions and Prolonged Progression-Free Duration Regardless of Age or Cytogenetic Risk after 5 Years of Follow up." Blood 132, Supplement 1 (November 29, 2018): 1957. http://dx.doi.org/10.1182/blood-2018-99-111712.
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Abstract Background: State of the art treatment for patients with NDMM involves induction with triplet-based regimens utilizing combinations of immunomodulatory drugs and proteasome inhibitors (PI) which improve time to progression (TTP), progression-free survival, and overall survival (OS) over doublet regimens. Carfilzomib is a selective PI with FDA approval in the KRd combination regimen for the treatment of patients with relapsed or refractory MM. Carfilzomib-based combinations are associated with increased clinical benefit over bortezomib-based combinations and carfilzomib does not cause neuropathy. This phase 2 study of 45 patients demonstrated that deep responses with KRd-r is achieved in the NDMM setting (Korde et al. JAMA Onc 2015). Here, we expand on our initial results in assessing response to present the long-term durability of minimal residual disease negativity (MRDneg) complete response (CR) and time to progression. We also characterize TTP by depth of response, age, and cytogenetic risk profile. Methods:Treatment-naïve patients with MM were treated for 8 cycles (28-day cycles) with carfilzomib 20/36 mg/m2 IV days 1, 2, 8, 9, 15, 16; lenalidomide 25 mg PO days 1-21, and dexamethasone 20/10 mg IV/PO days 1, 2, 8, 9, 15, 16, 22, 23. Transplant eligible patients underwent stem cell collection after ≥4 cycles and then continued KRd treatment (i.e. without default autologous stem cell transplant (ASCT)). After 8 cycles of KRd, patients received 2 years of lenalidomide 10 mg PO maintenance on days 1-21. The primary objective of the study was to estimate the rate of ≥ Grade 3 peripheral neuropathy with secondary objectives of International Myeloma Working Group criteria for overall response rate (ORR), MRDneg CR, TTP, and response duration (DoR) assessed after every cycle during induction and subsequently after every 90 days of maintenance therapy. Assessment of MRDneg CR by multi-color flow cytometry (bone marrow aspirate; 10-5 sensitivity) was performed after 8 cycles of induction, 1 and 2 years of lenalidomide maintenance, and then annually. Results: Forty-five patients meeting eligibility criteria were enrolled (60% male; 42% ≥ age 65, range 40-89; race: 82% White, 13% Black, 4% Asian; isotypes: 51% IgG kappa, 16% IgG lambda, 13% IgA kappa, 9% IgA lambda, 9% free kappa, and 4% free lambda; 33% high risk cytogenetics, del(17p), t(4;14), t(14;16)or t(14;20)). The median potential follow up was 5.7 years (68.3 months). The ORR was 97.8% (95% Confidence Interval (CI): 88.2-99.9%) with a median DoR of 65.7 months (95% CI: 55.6-not reached (NR) months). Strikingly, 28 of the 45 patients, 62.2%, (95% CI: 46.5-76.2%) attained deep responses of MRDneg CR; durability of MRDneg CR was observed up to at least 70 months with a median duration of over 4 years (52.4 months; 95% CI: 35.3-61.6 months). Moreover, the median TTP was over five and a half years (67.3 months; 95% CI: 51.0-NR months) and the median OS was NR, however, at 80 months, 84.3% of patients were still alive. As expected, patients who attained MRDneg CR, by cycle 8, had a 78% reduction in the risk of progression (Hazard Ratio (HR): 0.22 (95% CI: 0.07-0.69); p=0.005) (Figure 1). Importantly, these deep responses of MRDneg CR and long progression free durations were observed regardless of age group or cytogenetic-based risk profile (Table 1). Toxicities have been previously reported and were generally manageable with no Grade ≥ 3 neuropathy or death due to toxicity. Conclusions: Upfront treatment of NDMM with the modern and highly efficacious KRd-r regimen incorporating a "by-default-delayed" ASCT strategy led to high rates of MRDneg CR (10-5 sensitivity) which even more importantly were sustained with a median duration of over 4 years. Moreover, attaining MRDneg CR, was strongly associated with a delay in progression. Clinically important, we observed that these deep responses and long progression-free durations are observed regardless of age or cytogenetic risk and stress the importance of utilizing highly efficacious triplet-based regimens for these sub-categories of NDMM. Lastly, our results with KRd-r in NDMM compare favorably to ASCT-based regimens and question the use of upfront ASCT for all patients. Our observed median TTP of 67 months is approximately 17 months longer than published data using the regimen of bortezomib, lenalidomide, and dexamethasone with ASCT (Attal et al. NEJM 2017). Updated results will be presented at the Annual Meeting. Disclosures Korde: Amgen: Research Funding. Mailankody:Janssen: Research Funding; Juno: Research Funding; Takeda: Research Funding; Physician Education Resource: Honoraria. Landgren:Janssen: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Celgene: Consultancy, Research Funding; Amgen: Consultancy, Research Funding; Merck: Membership on an entity's Board of Directors or advisory committees; Karyopharm: Consultancy; Pfizer: Consultancy; Takeda: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding.
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Tucci, G., M. Betti, A. Conti, M. Corongiu, L. Fiorini, C. Matta, C. Kovačević, C. Borri, and C. Hollberg. "BIM FOR MUSEUMS: AN INTEGRATED APPROACH FROM THE BUILDING TO THE COLLECTIONS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-2/W11 (May 5, 2019): 1089–96. http://dx.doi.org/10.5194/isprs-archives-xlii-2-w11-1089-2019.
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<p><strong>Abstract.</strong> The paper discusses the first outcomes of an ongoing research activity aimed at developing a general BIM-based methodology for the organization and the management of the information needed for maintenance and safety assessment of museums. The Galleria dell’Accademia di Firenze (Florence, Italy) which has a very complex spatial organisation as a result of transformations occurred over the centuries, has been considered as an illustrative application of the proposed methodology. One of the specific elements which characterize museums, compared to other buildings, is the issue of the relationship between the building itself and the artworks there contained. A specific element of the research is consequently the need not to limit the attention to only the building (i.e. the envelope), but to consider within the BIM also the presence of the art collections. Starting from a recent laser scanner survey, a BIM has been created and a semi-automatic workflow has been investigated to obtain a FE (Finite Element) model to be employed for static and dynamic structural analysis purposes. Currently, since the scans inevitably included the artworks, a test is underway to add in the BIM of the museum also its collections (M-BIM). Each element can be inserted as a BIM object including its geometric representation and physical data (dimensions, materials, weight…) and linked to different museum inventory and conservation databases for the museum management.</p>
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Craker, Lyle E., and Zoë Gardner. "Dietary Supplements: The New Herbalism." HortTechnology 13, no. 2 (January 2003): 239–42. http://dx.doi.org/10.21273/horttech.13.2.0239.
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The passage of the Dietary Supplement Health and Education Act in 1994 made the use of supplements more acceptable in the U.S., increasing demand for botanicals to use in health care and maintenance. These botanicals, primarily medicinal and aromatic plants, currently represent about 25% of the dietary supplement market in the U.S. Although much of the market for botanicals traditionally has been met through collection of plants in the wild, enhanced cultivation of several species will be essential to bring standardized, quality plant materials into the marketplace.
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Ishanova, Muzaffara. "My profession is a museum expert." Infolib 25, no. 1 (March 30, 2021): 78–81. http://dx.doi.org/10.47267/2181-8207/2021/1-050.
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The article examines the specialty of a museologistart critic from the point of view of both the chosen professional field and a practicing museum worker. The theory and methodology of museums, research into the processes of preserving, collecting and broadcasting socially significant information through museum objects, the development and organization of various and specific areas of the sphere, the design of expositions, the maintenance of storage facilities, the search for information that sheds light on the features of a particular exhibit and its significance for the world art community and culture in general – these and many other functions of museum activities are fully disclosed by the author and, most importantly, in a fascinating form
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Hull, Larry A. "Apple, Evaluation of Insecticides on Indirect Pests, 1996." Arthropod Management Tests 22, no. 1 (January 1, 1997): 19–21. http://dx.doi.org/10.1093/amt/22.1.19.
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Abstract Experimental sprays were applied to single-tree plots in a randomized block design consisting of 4 replicates of ‘Yorking’. Treated single trees were separated by others not sprayed with insecticides. The trees were 8 years old and planted at a spacing of 20 x 30 ft. All treatments were applied with a Myers Mity Mist sprayer calibrated to deliver 100 gpa driven at 2.4 mph. All plots recieved a regular fungicide maintenance schedule of Benlate 50DF, Dithane 75DF, Nova 40WP and Ziram 76WP and the insecticide Imidan 70WP. All maintenance materials were applied using the alternate row middle method of application. The effect of the sprays on WALH was evaluated by counting the number of nymphs/25 injured leaves/tree. Effectiveness on the spirea aphid was evaluated by counting the number of aphid-infested leaves/10 top terminals, and by rating the density of aphids/most infested leaf on 0-4 scale as explained in the table footnotes. The number of natural enemies of aphids was determined by counting the number observed on 10 growing shoots per tree. Effectiveness of the test chemicals on ERM was evaluated by counting the mites several times during the season on samples of 25 random leaves/tree, 100 leaves/treatment. The predator, S. punctum, was observed by making 3-min counts of adults and larvae around the periphery of the trees. STLM was evaluated by a 5-min count of tissue-feeding mines around the periphery of the trees at the end of the 1st and 2nd generations. Also, STLM parasitism was evaluated at the end of the second generation by collecting 25 random leaves/tree and dissecting the mines found. Pest pressure was moderate throughout the season.
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Borges, Rafael, Wilian França Costa, Antonio Saraiva, Vera Imperatriz-Fonseca, and Tereza Giannini. "Natural History Collection Data: Traits to Identify Plant-Pollinator Interactions in a Spatial Context." Biodiversity Information Science and Standards 2 (July 4, 2018): e25857. http://dx.doi.org/10.3897/biss.2.25857.
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Natural history collections are of extreme importance as they safeguard data from both spatial and temporal sources. Biological collections store the biodiversity information of the majority of the world´s ecosystems, including data from extinct and threatened species. Worldwide, interactions betweens species perform important functions that contribute to the maintenance of the environment. The use of biodiversity by human society generates the so called Ecosystems Services (Nature’s Contributions to People), which may act at a local or even a global scale, as is the case with crop pollination services. Bees are the most important pollinator group and are responsible for the pollination of approximately 80% of Angiosperms and 75% of the crops worldwide. Bee pollinator decline has raised concern globally, the loss and degradation of habitat being one of the causes, with detrimental impacts on food production and biodiversity. In this context, we suggest incorporating and providing spatially explicit plant-pollinator interaction data into natural history collections databases. Plant-pollinator interaction traits (morphological, biochemical, physiological, structural, phenological or behavioural characteristics of organisms that influence performance or fitness) can firstly be identified through pollination syndromes by using floral traits such as size, shape, color, odor and the reward. Bee body size (estimated usually by intertegular distance) and tongue length are important traits that can be used to evaluate bee-flower compatibility and also to estimate an average flight range for each bee species through the landscape. Since interaction is context dependent, data on functional traits could be associated with spatial references, such as geographic coordinates, altitude and land use where species were collected. Such information is usually available in data repositories delivered by collections. Thus, the association of species identification, functional traits and occurrences can act as an important tool for understanding local ecosystem processes, to forecast impacts based on land use and climate change and also for assisting decision making processes for nature conservation. Online databases must also be linked to a Digital Object Identifier (DOI), as is the case for data plubications, so that the work of providing the data can be properly acknowledged and cited in the literature.
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Holle, Julia U., Christin Dubrau, Karen Herlyn, Martin Heller, Petra Ambrosch, Bernhard Noelle, Eva Reinhold-Keller, and Wolfgang L. Gross. "Rituximab for refractory granulomatosis with polyangiitis (Wegener's granulomatosis): comparison of efficacy in granulomatous versus vasculitic manifestations." Annals of the Rheumatic Diseases 71, no. 3 (October 21, 2011): 327–33. http://dx.doi.org/10.1136/ard.2011.153601.
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ObjectiveFirst, to investigate the overall efficacy and safety of rituximab (RTX) in refractory granulomatosis with polyangiitis (GPA) in a tertiary referral centre. Second, to compare the efficacy of RTX in granulomatous and vasculitic manifestations in GPA.Patients and methodsThis study comprised a retrospective, standardised data collection from all patients who received RTX for refractory Wegener's granulomatosis from 2002 to 2010. Patients were assessed by a standardised interdisciplinary diagnostic procedure (including ear, nose and throat and ophthalmology assessment, MRI, immunodiagnostics, B-cell levels and Birmingham Vasculitis Activity Score) and were treated by standardised therapeutic regimens according to available evidence.Results59 patients received 75 cycles of RTX. 9.3% achieved complete remission. A response was documented in 61.3% (improvement in 52%, unchanged disease activity in 9.3%), 26.7% had refractory disease. Birmingham Vasculitis Activity Score, disease extent index, erythrocyte sedimentation rate, C-reactive protein and prednisolone demand decreased significantly. All patients achieved B-cell depletion. Granulomatous manifestations such as orbital granuloma and pachymeningitis were more frequently refractory to RTX than vasculitis or other granulomatous manifestations. Thus, for example, complete remission/improvement was found in 89.2% of patients with renal disease and in only 44.4% of those with orbital masses (p=0.003). The relapse rate was 44.4% after a median period of 13.5 months. Adverse events occurred in 29%, pneumonia in 15% and death in 3%.ConclusionThe overall response rate of refractory GPA to RTX was high (61.3% complete remission or improvement). Response rates of vasculitic manifestations were excellent; failure of response/progress was mostly due to granulomatous manifestations, especially orbital masses. Relapse rates were high (40%) despite maintenance treatment.
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Shettigar, Savithri, Abhishek Somasekhara Aradhya, Srinath Ramappa, Venugopal Reddy, and Praveen Venkatagiri. "Reducing healthcare-associated infections by improving compliance to aseptic non-touch technique in intravenous line maintenance: a quality improvement approach." BMJ Open Quality 10, Suppl 1 (July 2021): e001394. http://dx.doi.org/10.1136/bmjoq-2021-001394.
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BackgroundLack of standardisation and failure to maintain aseptic techniques during procedures contributes to healthcare-associated infections (HCAI). Although numerous procedures are performed in neonatal intensive care units (NICU), handling peripheral intravenous lines is one of the simple and common procedures performed daily. Despite evidence-based care bundle approach variability is higher, and compliance to asepsis is less in routine clinical practice. In this study, we aimed to standardise and improve compliance with Aseptic non-technique (ANTT) in intravenous line maintenance of neonates admitted to NICU to reduce HCAI by 50% over 6 months.MethodsAll nurses were subjects of assessment for compliance with intravenous line maintenance. All admitted neonates with intravenous lines were subjects for the HCAI data collection. At baseline, the current practices for intravenous line maintenance were observed on a generic ANTT audit proforma. Pictorial standard operating procedure (SOP) was developed based on ANTT. Implementation and sustenance were ensured by Plan-Do-Study-Act cycles. Audit data on compliance to ANTT and trends of HCAI rates were displayed using run charts monthly. Qualitative experience from the nursing staff was also recorded.ResultsSignificant improvement was seen in compliance to various components—use of the aseptic field (0% to 100%), closed ports (0% to 100%), key part contamination reduction (80% to 0%), and intravenous hub scrubbing (0% to 72%). SOP of intravenous line maintenance based on ANTT could be implemented and sustained throughout for 9 months. There was a reduction of HCAI from 26 per 1000 patient days to 8 per 1000 patient days. Qualitative experience showed the main determinant of compliance to scrub the hub was the neonate’s sickness level.ConclusionsUsing a quality improvement model of improvement, ANTT in intravenous line maintenance was implemented stepwise. Improving compliance with ANTT principles in intravenous line maintenance reduced HCAI. Scrub the hub requires longer sustained efforts to become part of the practice.
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Gupta, Shivam, Albert Hamzin, and Auriol Degbelo. "A Low-Cost Open Hardware System for Collecting Traffic Data Using Wi-Fi Signal Strength." Sensors 18, no. 11 (October 25, 2018): 3623. http://dx.doi.org/10.3390/s18113623.
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Road traffic and its impacts affect various aspects of wellbeing with safety, congestion and pollution being of significant concern in cities. Although there have been a large number of works done in the field of traffic data collection, there are several barriers which restrict the collection of traffic data at higher resolution in the cities. Installation and maintenance costs can act as a disincentive to use existing methods (e.g., loop detectors, video analysis) at a large scale and hence limit their deployment to only a few roads of the city. This paper presents an approach for vehicle counting using a low cost, simple and easily installable system. In the proposed system, vehicles (i.e., bicycles, cars, trucks) are counted by means of variations in the WiFi signals. Experiments with the developed hardware in two different scenarios—low traffic (i.e., 400 objects) and heavy traffic roads (i.e., 1000 objects)—demonstrate its ability to detect cars and trucks. The system can be used to provide estimates of vehicle numbers for streets not covered by official traffic monitoring techniques in future smart cities.
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Lillis, Jason, and Dale S. Bond. "Values-based and acceptance-based intervention to promote adoption and maintenance of habitual physical activity among inactive adults with overweight/obesity: a study protocol for an open trial." BMJ Open 9, no. 1 (January 2019): e025115. http://dx.doi.org/10.1136/bmjopen-2018-025115.
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IntroductionDespite the importance of regular moderate-intensity to vigorous-intensity physical activity (MVPA) for health benefits and long-term weight management, current comprehensive lifestyle interventions have focused on providing MVPA prescriptions and goals but with only minimal and intermittent focus on psychosocial theoretical constructs and novel strategies, perhaps explaining the often modest impact on adoption and maintenance of higher levels of MVPA. An intervention based on acceptance and commitment therapy (ACT) targeting the increase of values-based autonomous motivation could improve the adoption and maintenance of habitual MVPA among insufficiently active overweight or obese adults in a brief intervention format.Methods and analysisThe overall aim of this study is to develop and test the feasibility, acceptability and preliminary efficacy of an ACT-based brief workshop intervention for increasing bouted MVPA for inactive adults with overweight/obesity using a single-arm design. A total of 48 inactive adults with overweight/obesity will be recruited and attend a 4-hour, ACT-based workshop followed by weekly emails and monthly phone calls for 3 months. The workshop will teach values clarification and acceptance-based skills to increase values-based autonomous motivation and bouted MVPA. Participants will self-monitor minutes of MVPA and personal values and report on progress via weekly emails and monthly phone calls. Assessments will be conducted at baseline and at 3 and 6 months.Ethics and disseminationStudy procedures have been approved by the Institutional Review Board. Consent is given in writing and in person. Data collection and storage separates study data from personally identifying information. Two safety officers who are not connected to the study monitor study progress and participant safety.Trial registration numberNCT03565731; Pre-results.
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Busch, Joseph A., and Angela Giral. "Subsidising end-user access to research databases: From Card File to the World Wide Web." Art Libraries Journal 22, no. 1 (1997): 38–42. http://dx.doi.org/10.1017/s0307472200010312.
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Through the last decade the Getty Art History Information Program (AHIP), recently renamed the Getty Information Institute, has been subsidising end-user online access to scholarly research databases. A study of subsidised access to Dialog databases provided to Getty Centre resident scholars has been reported by Marcia Bates, who found that searching patterns in humanities research differ substantially from those previously investigated in science and the social sciences. The cost of collecting research information and of making it available greatly exceeds revenues generated from its use; inability to measure use is an obstacle to justifying maintenance of subsidies at present levels. Key factors to be considered in assessing the relative value of different models of information provision include information quality, number of accesses, royalties received, user charges, producer subsidy, and user input. Analysis suggests that the non-profit method provides the best mode of access and supports the decision of AHIP to work in partnership with the Research Libraries Group.
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Haigler, Daniella. "Collections Access and Custom Storage Solutions at the Smithsonian’s Museum Support Center." Biodiversity Information Science and Standards 2 (July 17, 2018): e26223. http://dx.doi.org/10.3897/biss.2.26223.
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The National Museum of Natural History is committed to long-term stewardship of collections and to supporting their use by scientists and the general public. This stewardship role is unique among other US natural history museums. As the nation’s natural history museum, the National Museum of Natural History has a mandated commitment to conserve and protect its collections in a manner that will assure their continued accessibility by future generations and maintain the National Museum of Natural History mission. A significant number of objects from the National Museum of Natural History are permanently stored at the Museum Support Center in Suitland, MD. This space not only includes collections from the National Museum of Natural History (NMNH), but also the Museum Conservation Institute (MCI), the National Museum of American History (NMAH), the Hirshhorn Museum and Sculpture Garden (HMSG), the Freer Sackler Gallery (FSG) and the National Museum of African Art (AfA) as well as several other museums. In terms of collections access and use, the museum support center has a team, Collections Support Services (CSS), dedicated to collections’ long-term care and preservation. Collections Support Services provides access and support for the 730,000 square feet of collections housed at MSC. CSS staff perform a variety of technical and labor tasks related to the cleaning, preparation, packing, transport, unpacking, and permanent storage of objects and specimens. This includes building custom aluminum pallets for oversized objects and whale skull cradles. Moreover, while the use of palletized storage is not a new concept in museum storage, the construction of Pod 4 at the Museum Support Center in Suitland, MD posed some unique challenges for the permanent storage of oversized collections. Pod 4 provides continuous rows of 2', 4' and 8' deep cantilevered open racking from floor to ceiling (22 feet high), and allows palletized objects to be moved and placed in the racking via forklift. Traditional wooden pallets are unacceptable by archival standards, as they are acidic by nature, bulky, heavy, not fire-retardant, and prone to pest infestation. Collections Support Services circumvented these issues by establishing an innovative system of customized aluminum pallets for collections’ long-term care and preservation. These pallets are durable and lightweight, and must pass several quality control tests that include dropping and jarring. They are also designed with multiple functions in mind for ease of use, storage, transport, and maintenance.
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Hull, Larry A. "Pear, Seasonal Pear Psylla Control Experiment, 1994." Arthropod Management Tests 20, no. 1 (January 1, 1995): 39. http://dx.doi.org/10.1093/amt/20.1.39a.
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Abstract Experimental sprays were applied to replicated three tree plots in a block of ‘Bartlett’ (84%), ‘Bosc’ (9%), and ‘D’Anjou’ (7%) pears. Trees were planted to a spacing of 24 × 24 ft and were 15 years old. Each treatment was replicated four times in a RCB design. Experimental sprays were applied with a Friend Airmaster ‘309’ calibrated to deliver 100 gpa at 2.2 mph. All plots received a regular fungicide maintenance schedule of Benlate 50DF, Streptomycin and Ziran 76WP. All sampling was conducted on the middle ‘Bartlett’ tree in each replicate. All treatments were evaluated by counting eggs and/or nymphs from leaf samples using a binocular microscope under 10X magnification at 5-14 d intervals. Counts were made on 15 spur-leaf samples from 6 May to 18 May; on 5 spur and 10 third most distal leaf samples from 24 May to 30 Jun; and on 15 third most distal leaf samples on 7 Jul to 28 Jul. Adult PP were sampled by making two taps on eight limbs per center plot tree. All adults dropping onto 0.2 m2 collecting tray were counted. Pear fruits (25 per replicate) were rated as 0 (no russet), 1 (1-10% russeted surface), 2 (11-25% russeted surface), 3 (26-50% russeted surface), or 4 (>51% russeted surface). Possible ranges are 0-30 (none to 1-10% russeted surface), 31-60 (1-10% to 11-25% russeted surface), 61-90 (11-25% to 26-50% russeted surface), and 91-120 (26-50% to >51% russeted surface).
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Li, Li Fen. "Simple Ant Routing Algorithm for WSNs Used in Power Line Monitoring." Applied Mechanics and Materials 401-403 (September 2013): 1981–85. http://dx.doi.org/10.4028/www.scientific.net/amm.401-403.1981.
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The special class of wireless sensor networks for monitoring power transmission lines may extend for hundreds of miles in distances. The sensor nodes in this class of networks are deployed along narrowly elongated geographical areas and form a chain-type topology. Thus routing protocols in such environments must be kept as simple as possible. In this paper, we present the Simple Ant Routing Optimizing Algorithm (SAROA) to offer a low overhead solution in optimizing the routing process. Four improved strategies were used in our approach. During the route discovery we have used a new local search mechanism, in which each node broadcasts a control message (FANT) to its neighbors, but only one of them broadcast this message again. During the route maintenance phase, we only use data packets to refresh the paths of active sessions. Finally, the route repair phase is also enhanced, by using a deep search procedure as a way of restricting the number of nodes used to recover a route. A broadest search is only executed when the deeper one fails to succeed. The simulation results show that the enhance algorithm can effectively jump out of the local optimum and satisfy the tolerable delay in network-wide data collection.
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Under, Ilker, and Ender Gerede. "Silence in Aviation: Development and Validation of a Tool to Measure Reasons for Aircraft Maintenance Staff not Reporting." Organizacija 54, no. 1 (February 1, 2021): 3–16. http://dx.doi.org/10.2478/orga-2021-0001.
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Abstract Background and purpose: Organizational silence, seen as the greatest obstacle to the success of organizations and expressed as a refraining from expressing feelings, and ideas about problems encountered in their organizations, is identified as the avoidance of voluntary reporting in aviation organizations. The main purpose of this research is to identify and develop a tool to measure the various reasons for aviation employees’ remaining silent about the unsafe acts and events they witness, and the factors causing them to refrain from adopting safety enhancement proposals. Methodology: Within the scope of the study, a data collection tool was developed. Explanatory and confirmatory factor analysis of the data obtained from 483 employees was conducted to test the reasons for not reporting voluntarily in aviation. Results: As a result, it was found that employees did not participate in voluntary reporting due to factors of silence based on relational and prosocial factors, disengagement, quiescence and acquiescence, along with fear and defensiveness. Conclusion: Accordingly, organizations need to acknowledge and act with the awareness that organizational silence is a common phenomenon. The importance of voluntary reporting should be explained to employees at every opportunity and the number of quality voluntary reports should be increased. However, this should go beyond the simple slogans of ‘Safety comes first in this workplace’ or ‘Safety first’ hanging on the wall of every organization.
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Sakamoto, Joyce M., Terry Fei Fan Ng, Yasutsugu Suzuki, Hitoshi Tsujimoto, Xutao Deng, Eric Delwart, and Jason L. Rasgon. "Bunyaviruses are common in male and femaleIxodes scapularisticks in central Pennsylvania." PeerJ 4 (August 11, 2016): e2324. http://dx.doi.org/10.7717/peerj.2324.
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The blacklegged tickIxodes scapularisis widely distributed in the United States and transmits multiple pathogens to humans, wildlife and domestic animals. Recently, several novel viruses in the family Bunyaviridae (South Bay virus (SBV) and Blacklegged tick phlebovirus (BTPV)) were identified infecting femaleI. scapularisticks collected in New York State. We used metagenomic sequencing to investigate the distribution of viruses infecting male and femaleI. scapularisticks collected in Centre County, Pennsylvania. We identified both SBV and BTPV in both male and female ticks from all collection locations. The role of maleI. scapularisin pathogen epidemiology has been overlooked because they rarely bite and are not considered important pathogen vectors. However, males may act as reservoirs for pathogens that can then be transmitted to females during mating. Our data highlight the importance of examining all potential avenues of pathogen maintenance and transmission throughout the vector-pathogen life cycle in order to understand the epidemiology of tick-borne pathogens.
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Meizlish, Matthew L., Ruth A. Franklin, Xu Zhou, and Ruslan Medzhitov. "Tissue Homeostasis and Inflammation." Annual Review of Immunology 39, no. 1 (April 26, 2021): 557–81. http://dx.doi.org/10.1146/annurev-immunol-061020-053734.
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There is a growing interest in understanding tissue organization, homeostasis, and inflammation. However, despite an abundance of data, the organizing principles of tissue biology remain poorly defined. Here, we present a perspective on tissue organization based on the relationships between cell types and the functions that they perform. We provide a formal definition of tissue homeostasis as a collection of circuits that regulate specific variables within the tissue environment, and we describe how the functional organization of tissues allows for the maintenance of both tissue and systemic homeostasis. This leads to a natural definition of inflammation as a response to deviations from homeostasis that cannot be reversed by homeostatic mechanisms alone. We describe how inflammatory signals act on the same cellular functions involved in normal tissue organization and homeostasis in order to coordinate emergency responses to perturbations and ultimately return the system to a homeostatic state. Finally, we consider the hierarchy of homeostatic and inflammatory circuits and the implications for the development of inflammatory diseases.
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Hull, Larry A. "Pear, Seasonal Insecticide Evaluation for Pear Psylla, 1995." Arthropod Management Tests 21, no. 1 (January 1, 1996): 47–49. http://dx.doi.org/10.1093/amt/21.1.47.
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Abstract Experimental sprays were applied to replicated 3-tree plots in a block of ‘Bartlett’ (84%), ‘Bosc’ (9%), and ‘D’Anjou’ (7%) pears. Trees were planted at a spacing of 24 X 24 ft and were 16 years old. Each treatment was replicated 4 times in a randomized block design. Experimental sprays were applied with a Friend Airmaster ‘309’ calibrated to deliver 100 gpa at 2.2 mph. The first table contains a listing of the application dates. All plots received a regular fungicide maintenance schedule of Benlate 50DF, Streptomycin and Ziram 76WP. All sampling was conducted on the middle ‘Bartlett’ tree in each replicate. All treatments were evaluated by counting eggs and/or nymphs from leaf samples using a binocular microscope under 10 X magnification at 6-9 d intervals. Counts were made on 15 spur leaf samples from 1 May to 25 May, on 8 spur and 7 third most distal leaf samples from 1 Jun to 14 Jun, on 15 third most distal leaf samples on 22 Jun to 7 Jul. Adult PP were sampled by making 2 taps on 8 limbs per center plot tree. All adults dropping onto a 0.2 m2 collecting tray were counted. Russet evaluations were made on pear fruits (30 per replicate). Each replicate was rated as 0 (no russet), 1 (raised lenticels), 2 (1-10% russeted surface), 3 (11-25% russeted surface), 4 (26-50% russeted surface), or 5 (>51% russeted surface). The individual ratings were added to calculate a russet rating for each replicate. Possible ranges for the replicate russet ratings (and estimate of range of percent of surface russeted) are 0-30 (none to raised lenticels), 31-60 (raised lenticels to 1-10% russeted surface), 61-90 (1-10% to 11-25% russeted surface), 91-120 (11-25% to 26-50% russeted surface), and 121-150 (26-50% to >51% russeted surface).