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1

Tobin, J. G., S. A. Morton, S. W. Yu, T. Komesu, G. D. Waddill, and P. Boyd. "Spin Spectrometer at the ALS and APS." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 582, no. 1 (November 2007): 162–64. http://dx.doi.org/10.1016/j.nima.2007.08.098.

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Lu, Shun Bao, Wen Yuan Zhang, De Kui Niu, and Xiao Min Guo. "Effects of Soil NPK on Mechanical Properties of Culm-Wood of Ph. pubescens." Advanced Materials Research 160-162 (November 2010): 1669–73. http://dx.doi.org/10.4028/www.scientific.net/amr.160-162.1669.

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The mechanical properties of Ph. Pubescens were an important index to measure quality of bamboo. We research effects of soil available N (AN), available P (AP) and available K (AK) on mechanical properties of Ph. Pubescens in Jiangxi province. The results showed that there was no obvious regular between soil NPK content and mechanical properties of Ph. Pubescens. The anti-bending strength (ABS), anti-extension strength (AES) and anti-shears strength (ASS) of Ph. Pubescens were 148MPa, 98MPa and 15.6MPa, respectively, the maximum shear-force (MSF) was 2.0KN, and the anti-pressure strength (APS) was 59Mpa. The APS of all samples were higher than that of the middle timber. The APS was high why the vascular bundle of Ph. Pubescens arranges rules. The effect of AK on APS was larger than that of AN and AP. The MPF was 10.1 KN, The internal structures of bamboo determined their mechanical properties, so the anatomy of bamboo could also affect the mechanical properties of bamboo.
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3

Omelchenko, M. "Attenuated positive and negative symptoms in patients at clinical high-risk for psychosis." European Psychiatry 65, S1 (June 2022): S352. http://dx.doi.org/10.1192/j.eurpsy.2022.895.

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Introduction The clinical high-risk for psychosis (CHR) is mainly established by the presence of attenuated positive symptoms (APS), but there is evidence of the role of attenuated negative symptoms (ANS) in the development of psychotic spectrum disorders. It is important to establish a link between APS and ANS in patients at CHR in order to improve early detection of psychosis. Objectives Establish the relationship between APS and ANS in depressive patients at CHR. Methods 130 depressive young in-patients at CHR with APS (average age 19.5) and 71 ones with ANS (average age 19.5) were examined. The HDRS scale was used to assess depressive symptoms, the SOPS scale was used to assess APS and ANS, and the SANS scale was used to assess ANS. The results are presented in median values. Results No differences were found between two groups in the severity of depressive symptoms on the HDRS scale and CHR symptoms on the SOPS scale (22 vs 23.5 and 45 vs 43 respectively). Statistically valid differences have been established between the groups in the APS severity on the sub-scale of positive symptoms SOPS: 11 and 7 (p 0.001). No differences in the ANS severity on the sub-scale of negative symptoms were detected (17 and 18.5, p=0.207). There were also no differences in the ANS severity on the SANS scale (40 and 47, p=0.163). Conclusions It has been established that patients at CHR with APS also have ANS, which may have clinical significance for early detection of psychosis. Disclosure No significant relationships.
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Koller, Bruno, and Nicole Dettwyler. "APS Reinsurance." ASTIN Bulletin 27, no. 2 (November 1997): 329–37. http://dx.doi.org/10.2143/ast.27.2.542069.

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AbstractThis paper presents a new reinsurance product, called ‘Adaptive Pivot Smoothing’ (APS). It is designed to reduce the variance of the risk reinsured without affecting the mean. Investment theories have provided the idea for the product.
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5

Jones, Gavin. "APS Foreword." Asian Population Studies 11, no. 1 (January 2, 2015): 2–3. http://dx.doi.org/10.1080/17441730.2015.1010470.

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6

Cervera, R., MG Tektonidou, G. Espinosa, AR Cabral, EB González, D. Erkan, S. Vadya, et al. "Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations (I): catastrophic APS, APS nephropathy and heart valve lesions." Lupus 20, no. 2 (February 2011): 165–73. http://dx.doi.org/10.1177/0961203310395051.

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Maeyama, Marcos Aurélio, Camilla Macedo Cortez, Gabriela Goedert de Souza, Grazielle Bohora Silva Gonçalves, Jeniffer Kelen Santos Machado, Taís Nogara Novaes de Carvalho, Júlio César Corazza, Plínio Augusto Freitas Silveira, and Inajara Carla de Oliveira. "Política Nacional de Atenção Básica (2017): um golpe político-ideológico do capital." Inova Saúde 9, no. 2 (March 16, 2020): 236. http://dx.doi.org/10.18616/inova.v9i2.4386.

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Para responder a integralidade da atenção, o modelo de organização do SUS escolhido pelo Ministério da Saúde (MS) foi o da Atenção Primária à Saúde (APS), posteriormente no Brasil, denominada de Atenção Básica à Saúde (ABS). O motivo da denominação ABS foi pela tentativa de se diferenciar dos modelos seletivos internacionais, apostando num modelo de APS como estratégia estruturante do sistema. Desde sua implantação, a ABS acumula períodos de evolução e estagnação, tanto no que se refere à cobertura, quanto ao modelo adotado pelas equipes. Esses movimentos estão intimamente relacionados com a macro política adotada pelo MS para a APS apontada por meio de políticas e programas propostos. Nesse sentido, este artigo teve o objetivo de analisar as principais mudanças contidas na nova Política Nacional de Atenção Básica (PNAB), publicada em 2017, a partir de seu contexto histórico e político. Os resultados demonstraram que a nova PNAB, fruto de um movimento político-ideológico hegemônico, apresenta mudanças importantes quanto à estrutura das equipes, organização do processo de trabalho e financiamento, que fragilizam a consolidação da ABS como proposta abrangente para estruturação do sistema de saúde, dificultando o desenvolvimento da integralidade da atenção; e sugere que é necessário militância e participação social para que a política de saúde de fato responda aos interesses e necessidades da população.
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8

Liu, Xian-Liang, Jing-Yu Tan, Alex Molassiotis, Lorna K. P. Suen, and Yan Shi. "Acupuncture-Point Stimulation for Postoperative Pain Control: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–28. http://dx.doi.org/10.1155/2015/657809.

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The purpose of this study was to evaluate the effectiveness of Acupuncture-point stimulation (APS) in postoperative pain control compared with sham/placebo acupuncture or standard treatments (usual care or no treatment). Only randomized controlled trials (RCTs) were included. Meta-analysis results indicated that APS interventions improved VAS scores significantly and also reduced total morphine consumption. No serious APS-related adverse effects (AEs) were reported. There is Level I evidence for the effectiveness of body points plaster therapy and Level II evidence for body points electroacupuncture (EA), body points acupressure, body points APS for abdominal surgery patients, auricular points seed embedding, manual auricular acupuncture, and auricular EA. We obtained Level III evidence for body points APS in patients who underwent cardiac surgery and cesarean section and for auricular-point stimulation in patients who underwent abdominal surgery. There is insufficient evidence to conclude that APS is an effective postoperative pain therapy in surgical patients, although the evidence does support the conclusion that APS can reduce analgesic requirements without AEs. The best level of evidence was not adequate in most subgroups. Some limitations of this study may have affected the results, possibly leading to an overestimation of APS effects.
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9

Carmona-Ribeiro, Ana Maria, and Péricles Marques Araújo. "Antimicrobial Polymer−Based Assemblies: A Review." International Journal of Molecular Sciences 22, no. 11 (May 21, 2021): 5424. http://dx.doi.org/10.3390/ijms22115424.

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An antimicrobial supramolecular assembly (ASA) is conspicuous in biomedical applications. Among the alternatives to overcome microbial resistance to antibiotics and drugs, ASAs, including antimicrobial peptides (AMPs) and polymers (APs), provide formulations with optimal antimicrobial activity and acceptable toxicity. AMPs and APs have been delivered by a variety of carriers such as nanoparticles, coatings, multilayers, hydrogels, liposomes, nanodisks, lyotropic lipid phases, nanostructured lipid carriers, etc. They have similar mechanisms of action involving adsorption to the cell wall, penetration across the cell membrane, and microbe lysis. APs, however, offer the advantage of cheap synthetic procedures, chemical stability, and improved adsorption (due to multipoint attachment to microbes), as compared to the expensive synthetic routes, poor yield, and subpar in vivo stability seen in AMPs. We review recent advances in polymer−based antimicrobial assemblies involving AMPs and APs.
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10

Tektonidou, Maria G. "Renal Involvement in the Antiphospholipid Syndrome (APS)—APS Nephropathy." Clinical Reviews in Allergy & Immunology 36, no. 2-3 (December 2, 2008): 131–40. http://dx.doi.org/10.1007/s12016-008-8112-z.

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Asami, Tadao, Hiroyuki Koike, Yorinao Inoue, Nobutaka Takahashi, and Shigeo Yoshida. "Structure-Activity Relationships and Physiological Aspects of New Photosynthetic Electron Transport Inhibitors, 3-Alkylaminoalkyliden-2H-pyran-2,4(3H)-diones (APs)." Zeitschrift für Naturforschung C 43, no. 11-12 (December 1, 1988): 857–61. http://dx.doi.org/10.1515/znc-1988-11-1211.

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3-Aminoalkylidene-2H-pyran-2,4(3H)-diones (APs), possessing a conjugated enamino moiety which is common to cyanoacrylates and 2-aminoalkylidenecyclohexane-1,3-diones (ACs), were found as a new class of photosynthetic electron transport inhibitors. Although the structural requirement of APs for photosynthetic electron transport inhibition was very similar to that of cyanoacrylates and ACs, thermoluminescence measurements indicated that the binding manner of APs to D 1 protein was totally different from that of other inhibitors.
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12

Yudiati, Ervia, D. P. Wijayanti, N. Azhar, A. I. Chairunnisa, S. Sedjati, and Z. Arifin. "Alginate oligosaccharide/polysaccharide and lactic acid bacteria (Lactobacillus bulgaricus FNCC–0041 & Streptococcus thermophilus FNCC–0040) as immunostimulants against pathogenic Vibrio spp. using Artemia bio model." IOP Conference Series: Earth and Environmental Science 919, no. 1 (November 1, 2021): 012060. http://dx.doi.org/10.1088/1755-1315/919/1/012060.

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Abstract Alginate polysaccharide/oligosaccharide (APS/AOS) has been proven as a good immunostimulant. FNCC–0041 & FNCC–0040 are lactic acid bacteria (LAB) producing exopolysaccharides. Vibrio bacteria are pathogenic for aquatic cultivans. This study determines the performance of APS/AOS in combination with LAB as immunostimulants. These were conducted in Artemia challenge test assay against three species of Vibrio spp., namely Vibrio parahaemolyticus (Vp), V. harveyi (Vh), and V. vulnificus (Vv). The treatments were prepared by Factorial Design with two factors (APS/AOS doses and Vibrio spp.) and replicated three times. The APS/AOS concentration was 0, 300, 600, 900 ppm. There were 8 levels of vibrio challenges, namely non-Vibrio, Vp, Vh, Vv, Vp-Vh, Vh-Vp, Vv-Vp, and Vp-Vh-Vv. LAB and APS/AOS were fermented with seawater encapsulated by newly hatched Artemia’s nauplii for one hour. Ten nauplii were taken out and challenged with 108 cells/mL Vibrio. Its survival rate (SR) was counted every six hours until reached 100% mortality. Results show that SR of all nauplii Artemia bio encapsulated treatments was higher than control (p<0.05). The best survival rate was reached from 400 ppm AOS. It has appeared that there is a synergically positive effect among the bio encapsulated AOS and LAB to accelerate the Artemia’s immune system.
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García-Grimshaw, Miguel, Diego Rubén Posadas-Pinto, Amado Jiménez-Ruiz, Sergio Iván Valdés-Ferrer, Arturo Cadena-Fernández, José Jiram Torres-Ruiz, José Domingo Barrientos-Guerra, et al. "Antiphospholipid syndrome–mediated acute cerebrovascular diseases and long-term outcomes." Lupus 31, no. 2 (January 18, 2022): 228–37. http://dx.doi.org/10.1177/09612033221074178.

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Objectives The antiphospholipid syndrome (APS) is an autoimmune disease associated with thrombotic and non-thrombotic neurologic manifestations. APS is classified as primary (PAPS) or secondary (SAPS) when it co-exists with another autoimmune disease. We aim to describe the spectrum of acute cerebrovascular disease among patients with APS, their differences between stroke subtypes, and long-term functional outcomes. Methods Retrospective cohort study including adult (≥18 years) patients with APS followed in the stroke clinic of a tertiary-care reference center for autoimmune diseases in Mexico from 2009 to 2019. Results We studied 120 cases; 99 (82.5%) women; median age 43 years (interquartile range 35–52); 63.3% with SAPS. Demographics, comorbidities, and antiphospholipid antibodies (aPL) positivity were similar between APS type and stroke subtypes. Amongst index events, we observed 84 (70%) acute ischemic strokes (AIS), 19 (15.8%) cerebral venous thromboses (CVT), 11 (9.2%) intracerebral hemorrhages (ICH), and six (5%) subarachnoid hemorrhages (SAH). Sixty-seven (55.8%) were known patients with APS; the median time from APS diagnosis to index stroke was 46 months (interquartile range 12–96); 64.7% of intracranial hemorrhages (ICH or SAH) occurred ≥4 years after APS was diagnosed (23.5% anticoagulation-related); 63.2% of CVT cases developed before APS was diagnosed or simultaneously. Recurrences occurred in 26 (22.8%) patients, AIS, in 18 (69.2%); intracranial hemorrhage, in eight (30.8%). Long-term functional outcomes were good (modified Rankin Scale ≤2) in 63.2% of cases, during follow-up, the all-cause mortality rate was 19.2%. Conclusion We found no differences between stroke subtypes and APS types. aPL profiles were not associated with any of the acute cerebrovascular diseases described in this cohort. CVT may be an initial thrombotic manifestation of APS with low mortality and good long-term functional outcome.
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14

Jonitz, Günther, and Sonja Barth. "Patientenorientierung aus Sicht des Aktionsbündnisses Patientensicherheit e.V." Public Health Forum 19, no. 1 (April 1, 2011): 6–7. http://dx.doi.org/10.1016/j.phf.2010.12.003.

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EinleitungDas APS versteht sich als aktives Bündnis, das Patientenorientierung mit Patientensicherheit gleichsetzt: Patientensicherheit wird verstanden als gemeinsames Anliegen aller im Gesundheitswesen aktiv und passiv Beteiligten und kann auch nur in einem gemeinsamen Vorgehen erreicht werden. „Betroffene zu Beteiligten machen“ lautet die Grundidee des APS.
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15

Piuvezam, Grasiela, Vilani Medeiros de Araújo Nunes, Amanda Karolina Torres de Medeiros Alves, Candice Alves Esmeraldo, Mariela Samantha de Carvalho Costa, Mônica Larissa Padilha Honório, and Isac Davidson Santiago Fernandes Pimenta. "Idosos institucionalizados e a atenção primária no Brasil: a perspectiva dos profissionais de saúde." JMPHC | Journal of Management & Primary Health Care | ISSN 2179-6750 6, no. 2 (December 14, 2016): 205–22. http://dx.doi.org/10.14295/jmphc.v6i2.292.

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O objetivo foi investigar as ações realizadas em Instituições de Longa Permanência de Idosos (ILPI) pelos profissionais de saúde da atenção primária à saúde (APS) no Brasil. Estudo qualitativo em 11 municípios brasileiros. Utilizou-se entrevistas semiestruturadas com 82 profissionais de saúde. A análise foi realizada pelo software ALCESTE versão 4.9. Foram encontradas cinco classes nos discursos dos profissionais. A primeira, denominada Necessidade de profissionais da APS em atender idosos institucionalizados (54,61%) abordou o número reduzido de profissionais na APS e a necessidade de suprir a demanda. A classe 2 - Necessidade de capacitação dos profissionais da APS para atendimento aos idosos institucionalizados (18,43%) traz a necessidade de capacitar profissionais e o baixo investimento na APS. A classe 3 - Ações dos profissionais na APS (10,80%) mostrou que em todos os municípios há ausência de ações regulares nas ILPI. A Classe 4 - Atendimento para grupos específicos na APS (8,82%) evidenciou as insuficientes atividades desenvolvidas com idosos na APS. E a classe 5 - Sentimento do profissional que trabalha na APS (7,33%) mostrou que os profissionais gostam de trabalhar com idoso, mas, reconhecem necessidade de capacitação. Observou-se uma deficiência na APS quanto ao cuidado com idosos institucionalizados.
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Berney, Seth Mark. "Antiphospholipid Syndrome (APS)." Open Urology & Nephrology Journal 8, no. 1 (February 20, 2015): 1. http://dx.doi.org/10.2174/1874303x01508010001.

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17

Gualtieri, Devlin M., and W. W. Havens. "APS Instrument Group." Physics Today 38, no. 12 (December 1985): 11. http://dx.doi.org/10.1063/1.2814799.

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Orear, Jay. "APS and SDI." Physics Today 39, no. 3 (March 1986): 148. http://dx.doi.org/10.1063/1.2814948.

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Sostman, Henry Ernst. "APS Instrument Group." Physics Today 39, no. 5 (May 1986): 120. http://dx.doi.org/10.1063/1.2815024.

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20

Grabois, Martin. "APS treasurer's report." APS Journal 3, no. 2 (June 1994): 142–43. http://dx.doi.org/10.1016/s1058-9139(05)80346-8.

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21

Rosomoff, Hubert L. "APS committee reports." APS Journal 1, no. 1 (March 1992): 68–69. http://dx.doi.org/10.1016/s1058-9139(06)80019-7.

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22

Romano, Joan M. "APS board briefs." Pain Forum 4, no. 3 (September 1995): 203–4. http://dx.doi.org/10.1016/s1082-3174(11)80060-7.

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Romano, Joan M. "APS board briefs." Pain Forum 4, no. 1 (March 1995): 69–70. http://dx.doi.org/10.1016/s1082-3174(11)80082-6.

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Romano, Joan M. "APS board briefs." Pain Forum 5, no. 3 (September 1996): 221. http://dx.doi.org/10.1016/s1082-3174(96)80037-7.

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Romano, Joan M. "APS board briefs." Pain Forum 5, no. 1 (March 1996): 88–89. http://dx.doi.org/10.1016/s1082-3174(96)80077-8.

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Romano, Joan M. "APS board briefs." Pain Forum 6, no. 3 (September 1997): 204. http://dx.doi.org/10.1016/s1082-3174(97)70035-7.

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Romano, Joan M. "APS board briefs." Pain Forum 6, no. 1 (March 1997): 72. http://dx.doi.org/10.1016/s1082-3174(97)80017-7.

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Rosomoff, Hubert L. "APS committee reports." APS Journal 1, no. 3 (September 1992): 222–23. http://dx.doi.org/10.1016/1058-9139(92)90020-d.

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&NA;. "2011 APS Abstracts." Psychosomatic Medicine 73, no. 3 (April 2011): 1. http://dx.doi.org/10.1097/01.psy.0000396987.01117.50.

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ISHIBASHI, Masayoshi, Yuji SUWA, and Tomihiro HASHIZUME. "APS March 2000." Hyomen Kagaku 21, no. 9 (2000): 595–96. http://dx.doi.org/10.1380/jsssj.21.595.

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Bennett, Floyd C. "APS users meeting." Synchrotron Radiation News 1, no. 4 (July 1988): 8–10. http://dx.doi.org/10.1080/08940888808602504.

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32

Letichevsky, A. A., J. V. Kapitonova, and S. V. Konozenko. "Computations in APS." Theoretical Computer Science 119, no. 1 (October 1993): 145–71. http://dx.doi.org/10.1016/0304-3975(93)90343-r.

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Wilson, Wendell A. "Ethnicity and APS." Journal of Autoimmunity 15, no. 2 (September 2000): 153–55. http://dx.doi.org/10.1006/jaut.2000.0411.

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Collett-Solberg, Paulo F., Steven E. Nunn, Tara Beers Gibson, and Pinchas Cohen. "Identification of Novel High Molecular Weight Insulin-Like Growth Factor-Binding Protein-3 Association Proteins in Human Serum1." Journal of Clinical Endocrinology & Metabolism 83, no. 8 (August 1, 1998): 2843–48. http://dx.doi.org/10.1210/jcem.83.8.5053.

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abstract The insulin-like growth factor (IGF)-binding proteins (IGFBPs) carry IGFs in serum and regulate their activity and bioavailability. The main IGFBP in serum, IGFBP-3, is known to form a 150-kDa complex with IGFs and the acid-labile subunit (ALS). We investigated the binding of IGFBP-3 to additional association proteins in human serum (IGFBP-3 APs). Ligand blots, column chromatography, and affinity cross-linking experiments revealed the specific binding of IGFBP-3 to at least three novel serum proteins. These techniques demonstrated the presence of proteins with molecular masses of 70, 100, and 150 kDa that bind IGFBP-3 with high affinity. Serum ALS migrated separately (at 88 kDa) from the novel IGFBP-3 APs (as evident by Western immunoblot), and bound IGFBP-3 weakly (by reverse ligand blots). We also demonstrated that large amounts of one of the IGFBP-3 APs and small amounts of ALS were coimmunoprecipitated with IGFBP-3 from human serum. Similar to ALS, these IGFBP-3 APs are acid labile and lose their IGFBP-3 binding capacity after exposure to low pH. We conclude that there are several serum proteins in addition to ALS and IGFs that bind IGFBP-3 with high affinity. These IGFBP-3 APs may serve as an additional reservoir of IGFBP-3 or modulate its functions.
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Sciascia, S., and ML Bertolaccini. "Thrombotic risk assessment in APS: the Global APS Score (GAPSS)." Lupus 23, no. 12 (September 16, 2014): 1286–87. http://dx.doi.org/10.1177/0961203314541317.

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Cipriano, Tatiana Santos Pereira, Lívia de Oliveira Teixeira, Caroline Marques Hugolino de Araujo, Andréa Maria Duarte Vargas, and Efigênia Ferreira e. Ferreira. "O uso do PCATool (Primary care Assessment tool) como ferramenta de avaliação em saúde bucal: uma revisão de escopo." Research, Society and Development 11, no. 6 (April 23, 2022): e14111628834. http://dx.doi.org/10.33448/rsd-v11i6.28834.

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A Atenção Primária à Saúde (APS) é representada por meio dos atributos essenciais e derivados. O monitoramento constante da APS é fundamental para garantir melhores resultados para as condições de saúde. O PCATool é um instrumento validado que assegura a avaliação da APS baseada na estrutura e processo da atuação dos atributos essenciais e derivados. Esta revisão de escopo tem como objetivo mapear os estudos que avaliaram a qualidade das ações e serviços em saúde bucal na APS por meio do instrumento PCATool. A pergunta de pesquisa foi baseada na estratégia PCC (Population, concept, and contexto) e seguiu as recomendações PRISMA-ScR. Todos os estudos incluídos utilizaram o instrumento de avaliação PCATool para avaliar a qualidade dos serviços de saúde bucal ofertados na APS, sem restrição ao ano e idioma de publicação. Quatro estudos responderam aos critérios de inclusão e foram selecionados para análise das informações. Todos os estudos avaliaram a qualidade da saúde bucal na APS com base nos atributos essenciais e derivados do PCATool, totalizando dados de 2848 participantes. A maioria dos estudos encontraram uma alta qualidade da APS o que comprova a melhoria do serviço público de saúde bucal no Brasil, apesar de muitos usuários encontrarem dificuldade no acesso aos serviços de saúde bucal. Essa revisão de escopo encontrou poucos estudos que utilizaram o PCATool como ferramenta de avaliação, em serviços de saúde bucal. Portanto é recomendável que mais pesquisa utilizem a ferramenta e suas versões para uma avaliação consistente.
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Fukuda, Makoto, Miwa Miyazaki, Satoshi Uezumi, and Makoto Yoshida. "Design and assessment of the new APS dialyzer (APS-SA series)." Journal of Artificial Organs 9, no. 3 (September 29, 2006): 192–98. http://dx.doi.org/10.1007/s10047-006-0344-1.

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38

Rasia, Isabel Cristina Rosa Barros, Denise Silva Silveira, Pelayo Munhoz Olea, and Beatriz Barros Rasia. "Estruturação e orientação da atenção primária à saúde em um município no extremo sul do Brasil." Revista de Gestão em Sistemas de Saúde 9, no. 2 (July 17, 2020): 193–214. http://dx.doi.org/10.5585/rgss.v9i2.14493.

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Este estudo objetivou contextualizar a estrutura de organização e a orientação da Atenção Primária à Saúde (APS) de Pelotas, município do Rio Grande do Sul, bem como demonstrar e discutir a presença e a extensão dos atributos de orientação que qualificam a APS, por meio da aplicação do Instrumento Primary Care Assessment Tool (PCATool), avaliando a APS segundo o modelo de atenção (tradicional e Estratégia de Saúde da Família – ESF). Para tanto, realizou-se um estudo transversal, aplicando o PCATool aos 50 gestores das Unidades Básicas de Saúde (UBS) do município, no segundo semestre de 2015. Os resultados mostraram que o sistema de saúde de Pelotas está estruturado a partir de um modelo hierárquico baseado em níveis de complexidade crescente e que as UBS têm orientação em APS. No entanto, quando estratificadas por modelo de atenção, percebeu-se que somente as que trabalhavam com a ESF estavam orientadas. Conclui-se, assim, que o modelo de ESF traz melhorias à APS, demandando uma reestruturação interna das UBS e, consequentemente, das equipes de trabalho. Além disso, no que concerne ao PCATool, explicitam-se críticas quanto ao escore acesso, e à perda de algumas dimensões importantes qualitativas da organização e do serviço no que concerne à assistência prestada aos usuários. Por fim, destaca-se que ter orientação em APS não é garantia de qualidade assistencial praticada.
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Southwick, Jeffrey G., Carl van Rijn, Esther van den Pol, Diederik van Batenburg, Arif Azhan, Ahmadanis Kalantar, and Nazliah Zulkifli. "Advantages of an APS/AES Seawater-Based Surfactant Polymer Formulation." SPE Journal 25, no. 06 (September 3, 2020): 3494–506. http://dx.doi.org/10.2118/190296-pa.

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Summary A low-complexity chemical flooding formulation has been developed for application in offshore environments. The formulation uses seawater with no additional water treatment beyond that which is normally performed for waterflooding (filtration, deoxygenation, etc.). The formulation is a mixture of an alkyl propoxy sulfate (APS) and an alkyl ethoxy sulfate (AES) with no cosolvent. With seawater only (no salinity gradient), the blend of APS and AES gives substantially higher oil recovery than a blend of APS and internal olefin sulfonate (IOS) in outcrop sandstone. This formulation also reduces complexity, increases robustness, and potentially improves project economics for onshore projects as well. It is shown that the highest oil recovery is obtained with surfactant blends that produce formulations that are underoptimum (Winsor Type I phase behavior) with reservoir crude oil. Also, these underoptimum formulations avoid the high-injection pressures that are seen with optimum formulations in low-permeability outcrop rock. The formulation recovers a similar amount of oil in reservoir rock in the swept zone. Overall recovery in reservoir rock is lower than outcrop sandstone due to greater heterogeneity, which causes bypassing of crude oil. A successful formulation was developed by first screening surfactants for phase behavior then fine tuning the formulation based on insights developed with corefloods in consistent outcrop rocks. The consistency of the outcrop is essential to understand cause and effect. Then, final floods were performed in reservoir rock to confirm that low interfacial tension (IFT) is propagated through the core.
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Shu, Deming, Tony Warwick, and Erik D. Johnson. "Diagnostic phosphors for photon beams at the ALS and APS." Review of Scientific Instruments 63, no. 1 (January 1992): 548–49. http://dx.doi.org/10.1063/1.1142702.

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OGUCHI, Tooru, Yukiko MINO, Shota KASAI, Takaki MAKINO, and Yoshio OTANI. "Addiction Scales (APS, AAS) in Supplementary Scales of MMPI-2." Proceedings of the Annual Convention of the Japanese Psychological Association 75 (September 15, 2011): 2PM003. http://dx.doi.org/10.4992/pacjpa.75.0_2pm003.

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Alves de Carvalho, Vanessa Karoline, Dannielle Fernandes Godoi, Filipe de Barros Perini, and Ana Cristina Vidor. "Cuidado compartilhado de pessoas vivendo com HIV/AIDS na Atenção Primária." Revista Brasileira de Medicina de Família e Comunidade 15, no. 42 (May 30, 2020): 2066. http://dx.doi.org/10.5712/rbmfc15(42)2066.

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Introdução: Buscando instituir ações para prevenir e reduzir a transmissão, melhorar o acesso ao tratamento e a qualidade de vida das pessoas vivendo com HIV/AIDS (PVHIV), a rede municipal de saúde de Florianópolis implantou entre 2015 e 2016 uma nova forma de suporte em Infectologia para a Atenção Primária a Saúde (APS). Objetivo: Descrever os resultados encontrados no município no processo de descentralização e cuidado compartilhado de pessoas vivendo com HIV/AIDS (PVHIV) com a APS de Florianópolis. Métodos: Trata-se de um estudo observacional, transversal e descritivo. Os dados foram obtidos de relatórios do prontuário eletrônico local e a partir de questionário estruturado aplicado junto aos médicos da APS de Florianópolis. Resultados: Entre 2014 e 2018, o número de atendimentos na APS relacionados ao cuidado de PVHIV teve um aumento expressivo, sobretudo após 2016, acompanhado de uma redução de 45,7% na proporção de encaminhamentos para infectologia após a implantação do apoio matricial em infectologia. Aliada à redução da taxa de encaminhamento evidenciou-se a habilidade na prescrição de Terapia Antirretroviral (TARV) por 100% dos médicos da APS entrevistados. Em relação à situação de acompanhamento de PVHIV, exclusivamente sob cuidados da APS, foi encontrada diferença estatisticamente significante entre os médicos que fazem preceptoria em ensino na graduação e residência e os que são residentes ou tem formação específica em medicina de família e comunidade (MFC) em relação aos médicos sem formação específica. A proporção de médicos que se sentem seguros e confiantes em realizar esse tipo de atendimento na APS também foi significativamente maior entre os médicos que fazem preceptoria e são médicos de família e comunidade. Conclusões: A implantação do Apoio Matricial da Infectologia para a APS trouxe grande avanço para o município de Florianópolis, no que tange ao acesso e qualificação do cuidado das pessoas vivendo com HIV/AIDS. Os resultados foram mais significativos para os profissionais envolvidos com atividades de preceptoria e formação específica em MFC, o que reforça o papel da educação permanente na qualificação da coordenação do cuidado pela APS.
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Rose, Thomas, and Thomas Dörner. "Das Antiphospholipidsyndrom." Arthritis und Rheuma 39, no. 01 (February 2019): 37–43. http://dx.doi.org/10.1055/a-0828-6613.

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ZusammenfassungDas Antiphospholipidsyndrom (APS) ist eine seltene Erkrankung, die klinisch mit thrombembolischen Ereignissen einhergeht und häufig verbunden ist mit Schwangerschaftskomplikationen. Die Antiphospholipid-Antikörper sind ein zentraler Bestandteil in der Pathogenese des APS und haben über den prokoagulatorischen Effekt hinaus Auswirkungen auf das Immunsystem. Der Nachweis der Antiphospholipid-Antikörper gilt bei Gesunden als Risiko für thrombembolische Ereignisse und die sogenannte Tripel-Positivität ist dabei mit einem besonders hohen Risiko für thrombembolische Ereignisse verbunden. Die Therapie des APS ist abhängig von der klinischen Konstellation und umfasst die Gabe von ASS und Vitamin-K-Antagonisten bzw. Heparin. Die direkten orale Antikoagulanzien sind zwar häufig im Label anwendbar, allerdings zeigt eine aktuelle Studie eine höhere Rezidivrate bei tripel-positiven APS-Patienten unter Rivaroxaban.
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Laport, Tamires Jordão, Pedro Henrique Antunes da Costa, Daniela Cristina Belchior Mota, and Telmo Mota Ronzani. "Percepções e Práticas dos Profissionais da Atenção Primária à Saúde na Abordagem sobre Drogas." Psicologia: Teoria e Pesquisa 32, no. 1 (March 2016): 143–50. http://dx.doi.org/10.1590/0102-37722016012055143150.

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RESUMO Este estudo teve como objetivo analisar as percepções dos profissionais da Atenção Primária à Saúde (APS) em relação às práticas de prevenção e à abordagem ao usuário de álcool e outras drogas, levantando desafios e possibilidades da APS. Através de grupos focais, participaram 18 profissionais da APS de um município de pequeno/médio porte do estado de Minas Gerais, Brasil. Os resultados sugerem que há um discurso a favor das práticas preventivas, mas enfoque no curativismo; limitada participação dos usuários nas atividades preventivas; dificuldade na abordagem aos usuários de drogas; sobrecarga de trabalho; ausência de engajamento dos médicos; cobertura assistencial insuficiente; falta de suporte da gestão, entre outros fatores que obstaculizam o desenvolvimento das ações preventivas e interferem na abordagem aos usuários de drogas.
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Romay-Penabad, Zurina, Guadalupe Montiel-Manzano, Elizabeth Pappalardo, Katherine A. Hajjar, Tuya Shilagard, Gracie Vargas, and Silvia S. Pierangeli. "Annexin A2 Deficient Mice Are Resistant to Pathogenic Effects of Antiphospholipid Antibodies in Vivo." Blood 112, no. 11 (November 16, 2008): 421. http://dx.doi.org/10.1182/blood.v112.11.421.421.

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Abstract Background: Thrombosis is an important cause of morbidity and mortality in Antiphospholipid Syndrome (APS) and in SLE patients with antiphospholipid antibodies (aPL). APL recognize β2 glycoprotein I (β2GPI)-bound to receptor (s) in endothelial cells (EC) and other target cells (i.e. platelets, monocytes) and trigger an intracellular signalling and a pro-coagulant and pro-inflammatory phenotype [i e.expression of tissue factor (TF), vascular cell adhesion molecule-1 (VCAM-1)] that lead to thrombosis. There is in vitro evidence that annexin A2 (A2), a receptor for tissue plasminogen activator (tPA) and plasminogen – and possibly other proteins such as toll-like receptors or the receptor for apolipoprotein E2′ - may be binding β2GPI on the membrane of target cells. Here, we examined the involvement of A2 in aPL-mediated pathogenic effects in vivo. We studied the effects of aPL Abs on thrombus formation, VCAM-1 expression in aortas of mice, and TF function in carotid artery homogenates in annexin A2 deficient (−/−) mice. Methods: A2 (−/−) mice and the corresponding wild-type (WT) mice, in groups of 10, were injected i.p. twice (0 and 48 hours later) with IgG from a patient with APS (IgG-APS) or with control IgG (IgG-NHS). Seventy-two hours after the first injection, several procedures were done in each mice: dynamics of thrombus formation (thrombus size), TF function in homogenates of carotid arteries, and c) VCAM-1 expression in the aortas using quantum dot nano crystals and two-photon excitation laser scanning microscopy. In addition, we examined the effect of an anti-A2 antibody on aPL-induced expression of intercellular cell-adhesion molecule (ICAM-1), E-selectin and TF acvitity on cultured endothelial cells (EC). Results: The titers of aCL and anti-β2GPI Abs in the sera of the mice at the time of surgery were medium-high positive in A2 (−/−) mice and in wild type mice injected with IgG-APS. Thrombus sizes were significantly larger in WT mice injected with IgG-APS when compared to similar type of mice treated with IgG-NHS (p=0.003). The size of thrombus in A2 (−/−) mice injected with IgG-APS was significantly smaller than mean thrombus size in WT mice injected with IgG-APS (p:0.0005). However, thrombus size in A2 (−/−) mice was larger in mice injected with IgG-APS when compared to same type of mice treated with control IgG-NHS (p=0.003), indicating a partial but significant abrogation of the thrombogenic effect. TF activity was significantly larger in WT mice treated with IgG-APS when compared to mice injected with IgG-NHS. Importantly, TF activity in carotid arteries homogenates of annexin A2 (−/−) mice injected with IgG-APS was significantly decreased (by 52%) when compared to wild type mice treated with IgG-APS. The expression of VCAM-1 in aorta of annexin A2 (−/−) ex vivo was also significantly reduced compared to LPS-treated mice (positive control) (p= 0.01). Interestingly, anti-A2 antibody significantly decreased aPL-induced expression of ICAM-1, E-sel and TF on cultured EC. Conclusions: Altogether these data indicate for the first time that A2 is involved in vivo pathogenic effects of aPL Abs. These findings may have important implications to devise new targeted and more specific therapeutic approaches to block the pathogenic effects of aPL Abs in patients with APS and SLE.
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Norman, Armando Henrique. "Estratégias que viabilizam o acesso aos serviços de Atenção Primária à Saúde no Reino Unido." Revista Brasileira de Medicina de Família e Comunidade 14, no. 41 (August 7, 2019): 1945. http://dx.doi.org/10.5712/rbmfc14(41)1945.

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Este artigo apresenta algumas características organizativas e operacionais da Atenção Primária à Saúde (APS) inglesa. Seu objetivo é evidenciar pontos relevantes no funcionamento das clínicas da APS que facilitam o equilíbrio dinâmico entre o atendimento à demanda espontânea e as ações programáticas em saúde. Ele tem como base um estudo etnográfico, realizado no Reino Unido no período de 2013/14, no qual se analisou o modelo de pagamento por desempenho no país. Os tópicos abordados incluem: (a) composição das equipes da APS inglesa; (b) organograma funcional de uma clínica de APS; (c) consulta de 10 minutos dos médicos de família e horário de funcionamento da clínica; (d) recepção; (e) equipe de enfermagem; e (f) sistema de tecnologia da informação. Cada um desses itens possui referências para as quais é possível explorar websites e tutoriais de modo a compreender melhor alguns aspectos das clínicas da APS inglesa. O Reino Unido profissionalizou o acesso dos pacientes aos serviços da APS. Isto ocorreu por meio de um contingente maior de pessoal administrativo, menor proporção população/médico de família, maior autonomia da equipe de enfermagem e um robusto sistema de tecnologia da informação. No Brasil, a Estratégia Saúde da Família (ESF) necessita percorrer caminho semelhante a fim de aprimorar a qualidade da APS no país.
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Tu, Tian Ming, Sheena SH Phua, Sanchalika Acharyya, Wai May Ng, and Daniel CT Oh. "Predicting Pneumonia in Acute Ischaemic Stroke: Comparison of Five Prediction Scoring Models." Annals of the Academy of Medicine, Singapore 46, no. 6 (June 15, 2017): 237–44. http://dx.doi.org/10.47102/annals-acadmedsg.v46n6p237.

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Introduction: Although pneumonia is a major complication after acute ischaemic stroke (AIS), pneumonia prediction scores have not been extensively validated. This study aimed to compare the discrimination performance of 5 pneumonia prediction scores in AIS patients. Materials and Methods: We retrospectively reviewed all consecutive adult AIS patients whom presented to our emergency department within 4.5 hours of symptom-onset between January 2012 and February 2015. Diagnosis had to be made by a neurologist and infarcts confirmed by neuroimaging. We excluded patients with pneumonia on presentation. Pneumonia predictors were based on the 5 prediction scoring models: Kwon’s score, Chumbler’s score, Acute Ischaemic Stroke-Associated Pneumonia Score (AIS-APS), A2DS2 score and ISAN score. The definition of stroke-associated pneumonia was based on the criteria by the Pneumonia in Stroke Consensus Group. Analysis using area under receiver operating characteristics curve (AUROC) was performed. Results: Forty (5.5%) out of 731 patients analysed had stroke-associated pneumonia (SAP). A2DS2 score had the highest discrimination capacity (AUROC 0.88; 95% CI, 0.84 to 0.92), followed by AIS-APS (AUROC 0.87; 95% CI, 0.83 to 0.91), Kwon’s score (AUROC 0.86; 95% CI, 0.82 to 0.92), Prestroke Independence, Sex, Age and National Institutes of Health Stroke Scale (ISAN) score (AUROC 0.85; 95% CI, 0.80 to 0.90) and Chumbler’s score (AUROC 0.79; 95% CI, 0.74 to 0.84). However, there was no statistical difference of discrimination capacity among A2DS2 score, AIS-APS and Kwon’s score. Conclusion: A2DS2, AIS-APS and Kwon’s scores performed comparably in discriminating SAP in AIS patients. Key words: Prognosis, Epidemiology, Retrospective studies, Validation, Singapore, Brain ischaemia/complications
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Tasca, Renato, Wellington Mendes Carvalho, Rosane De Mendonça Gomes, Iasmine Lorena Silva Ventura, Vanessa Pinheiro Borges, Fernando Antônio Gomes Leles, Flávio Alberto de Andrade Goulart, and Julio Manuel Suarez Jimenez. "Acesso aos serviços de atenção primária à saúde no Sistema Único de Saúde: Fortalezas e desafios emergentes das experiencias apresentadas ao Prêmio “APS Forte para o SUS”." APS EM REVISTA 2, no. 3 (September 4, 2020): 198–212. http://dx.doi.org/10.14295/aps.v2i3.145.

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O artigo visa identificar, dar visibilidade, reconhecer e promover iniciativas locais, municipais ou regionais que tenham como foco a melhoria do acesso aos serviços de APS. Esta iniciativa buscou experiências que promoveram este atributo, reforçando o papel da APS como porta de entrada prioritária e coordenadora da atenção no sistema de saúde.
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Oliveira, Stéphany Ketllin Mendes, Mayane Moura Pereira, André Luiz Sena Guimarães, and Antônio Prates Caldeira. "Autopercepção de saúde em quilombolas do norte de Minas Gerais, Brasil." Ciência & Saúde Coletiva 20, no. 9 (September 2015): 2879–90. http://dx.doi.org/10.1590/1413-81232015209.20342014.

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Resumo Comunidades quilombolas vivenciam situação de vulnerabilidade social, mesmo mais de um século da abolição da escravatura, principalmente em relação aos cuidados de saúde. O estudo objetivou conhecer a autopercepção da saúde (APS) em comunidades quilombolas do Norte de Minas Gerais e os fatores associados à percepção negativa da própria saúde. Inquérito domiciliar com amostra representativa das comunidades quilombolas da região estudada. Foram utilizados instrumentos validados para coleta de dados sobre a APS, condições socioeconômicas e demográficas, hábitos de vida e morbidade autorreferida. Após análise bivariada, conduziu-se análise de regressão logística hierarquizada. A prevalência de APS negativa foi de 46,0%. As seguintes variáveis mostraram-se estatisticamente associados a uma APS negativa: idade e escolaridade, como variáveis distais e hipertensão, diabetes, artrite, depressão e problemas de coluna como variáveis proximais. A APS mostrou-se associada a dimensões demográficas, socioeconômicas e, especialmente, à morbidade autorreferida. O conceito de saúde para as comunidades quilombolas estudadas parece estar intimamente ligado à ausência de doenças, especialmente as crônicas.
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Saito, Danielle Yuri Takauti, and Elma Lourdes Campos Pavone Zoboli. "Cuidados paliativos e a atenção primária à saúde: scoping review." Revista Bioética 23, no. 3 (December 2015): 593–607. http://dx.doi.org/10.1590/1983-80422015233096.

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Resumo O envelhecimento da população aumentou a incidência de doenças crônicas, demandando a inserção dos cuidados paliativos (CP) em diferentes níveis da rede, incluindo a atenção primária à saúde (APS). Isso poderá interferir nas questões éticas da APS. A presente pesquisa teve como objetivo identificar, na visão dos profissionais de saúde, os problemas éticos decorrentes da prática dos CP na APS. Fez-se revisão sistemática nas bases PubMed, Embase, Lilacs, CINAHL, com os descritores “ética”, “bioética”, “atenção primária à saúde” e “cuidados paliativos”. Localizaram-se 3.915 artigos, restando 16, após a análise. Os problemas éticos detectados foram: escassez de recursos; desconhecimento sobre CP; falta de habilidades comunicacionais; dificuldade de estabelecer limites na relação clínica; sobrecarga de trabalho; falta de apoio dos serviços de referência. Na abrangência, esses problemas assemelham-se aos vividos na APS, com diferenças nas situações específicas. Para incorporar os CP na APS, são necessárias normatizações e formação específicas, além da cultura do cuidado compartilhado e corresponsável.
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