Academic literature on the topic 'Approche familiale (Family-based)'
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Journal articles on the topic "Approche familiale (Family-based)"
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Cheers, Brian, Margaret Binell, Heather Coleman, Ian Gentle, Grace Miller, Judy Taylor, and Colin Weetra. "Family violence." International Social Work 49, no. 1 (January 2006): 51–63. http://dx.doi.org/10.1177/0020872806059401.
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English A study in an Australian Aboriginal community identified a new way of knowing family violence, locating it in the historical context of colonization, oppression, dispossession, disempowerment, dislocation and poverty. A community development approach to addressing family violence was developed based on this understanding and the strengths of the community. French Cette étude menée au sein d'une communautéaborigè ne d'Australie détermine une nouvelle fac¸ on d'appréhender la violence familiale en situant le problè me dans le contexte historique de la colonisation, de l'oppression, de la dépossession, de la déresponsabilisation, de la dislocation et de la pauvreté. Cette compréhension du phénomè ne a permis d'élaborer une approche de développement communautaire pour contrer la violence familiale, qui fait aussi appel aux forces de la communauté. Spanish Un estudio en una comunidad australiana aborigen identificó una nueva manera de entender la violencia doméstica, localizá ndola en el contexto histó rico de colonizació n, opresió n, desposesió n, falta de poder, desplazamiento y pobreza. Se desarrolló una metodología de desarrollo comunitario basado en este nuevo entendimiento y en las cualidades positivas de la comunidad.
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William Victora. "La orientación en familias de niños con autismo: Un abordaje necesario." GACETA DE PEDAGOGÍA, no. 44 (November 30, 2022): 90–102. http://dx.doi.org/10.56219/rgp.vi44.1248.
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El presente artículo tuvo como finalidad plantear aproximaciones teóricas sobre el impacto del autismo en la familia y su abordaje desde la orientación. Es por ello, que se tomaron algunos referentes teóricos de la orientación familiar; se presenta una definición del autismo, sus características y cómo afecta en la familia, particularmente en los padres. La metodología empleada se basó en un diseño documental y como técnica se aplicó el análisis de contenidos. Como resultado se obtuvo que el autismo es un trastorno complejo que impacta en el ámbito familiar, desde lo emocional al surgir sentimientos de ansiedad, depresión, confusión o estrés; además los padres deben reorganizarse y hacer modificaciones al espacio físico del hogar. Se concluyó que desde la orientación familiar como proceso de ayuda se pueden destinar acciones para mejorar la dinámica funcional de las familias.
ABSTRAC
The purpose of this article was to propose theoretical approaches about the impact of autism in the family and its approach from the orientation. It is for this reason that some theoretical references of family orientation were taken; A definition of autism, its characteristics and how it affects the family, particularly the parents, is presented. The methodology used was based on a documentary design and content analysis was applied as a technique. As a result, it was obtained that autism is a complex disorder that impacts the family environment, from the emotional point of view, when feelings of anxiety, depression, confusion or stress arise; In addition, parents must reorganize and make modifications to the physical space of the home. It was concluded that from the family orientation as a help process, actions can be assigned to improve the functional dynamics of families.
Key words: Orientation, Autism, Family
RESUMÉ
Le but de cet article est de proposer des approches théoriques sur l'impact de l'autisme dans la famille et son approche à partir de l'orientation. C'est pour cette raison que quelques références théoriques de l'orientation familiale ont été prises ; Une définition de l'autisme, de ses caractéristiques et de ses effets sur la famille, notamment les parents, est présentée. La méthodologie utilisée était basée sur une conception documentaire et l'analyse de contenu a été appliquée en tant que technique. En conséquence, il a été obtenu que l'autisme est un trouble complexe qui affecte l'environnement familial, du point de vue émotionnel, lorsque surviennent des sentiments d'anxiété, de dépression, de confusion ou de stress ; De plus, les parents doivent réorganiser et apporter des modifications à l'espace physique de la maison. Il a été conclu qu'à partir de l'orientation familiale en tant que processus d'aide, des actions peuvent être assignées pour améliorer la dynamique fonctionnelle des familles.
Mots clés: Orientation, Familial, Autisme
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Bolaji, A. I., T. O. Ojebode, O. S. Adekanye, and A. O. Bolaji. "Influence of Family Structure and Functionality on Immunization Status of Infants Attending GOPC of BMC Saki." Research Journal of Health Sciences 8, no. 3 (October 9, 2020): 163–74. http://dx.doi.org/10.4314/rejhs.v8i3.2.
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Introduction: Vaccine-preventable diseases are endemic in Nigeria, and contribute greatly to childhood morbidities and mortalities. Good family structure has been reported to improve children's wellbeing, health and eating habit, but the contribution of family structure together with family functionality on immunization status has not been documented. Overall, the goal of the research was to determine the level of immunization status in the study population, assess their knowledge of immunization and determine what influence family structure and functionality have on children's immunization status.Methods: A cross-sectional descriptive study was conducted in 2016 in the General outpatient clinic (GOPC) of Baptist Medical Centre (BMC), Saki, Oyo State. Family APGAR Scale and self-design questionnaire were used to collect data from 299 respondents using systematic sampling technique. A SPSS (version 21) was used for the analysis.Results: Our results showed that 82.9% of the respondents were fully immunized and 98% had knowledge about Immunization. Majority of the respondents came from functional families, accounting for 85.6% of cases. The following factors were found to be statistically significantly associated with immunization status: family functionality (X2 = 101.694, P = 0.000), family type (p value =0.000), family size (p value = 0.000), ethnic group (p value = 0.000) and number of children (P value = 0.000)Conclusion: Our findings showed that there is an adequate knowledge of immunization in the study population, and that a child's immunization status is significantly influenced by the family structure and functionality. However, given the fact that this is a single, hospital-based study, several multi-center studies would have to be employed not just to validate this conclusion but also to inform policy making.
Keywords: Immunization status, family structure, family functionality, vaccine, health facility, Nigeria
French Title: Influence de la structure familiale et de la fonctionnalité sur le statut de vaccination des nourrissons assistant au GOPC de BMC, Saki
Les morts évitables par la vaccination restent endémiques et contribuent de manière significative à la morbidité infantile au Nigéria et il a été reconnu qu'une bonne structure familiale améliore le bien-être, la santé et les habitudes alimentaires des enfants, mais la contribution de la structure et de la fonctionnalité de la famille au statut vaccinal n'est pas encore établie. Le but de cette étude est de déterminer le niveau d'immunisation des répondants, d'évaluer leurs connaissances en matière d'immunisation et de déterminer l'influence de la structure et de la fonctionnalité de la famille sur l'état de vaccination.
Méthode de l'étude: Une étude descriptive transversale a été menée en 2016 dans la clinique externe générale (GOPC) du Baptist Medical Center (BMC), Saki, dans l'état d'Oyo. L'échelle familiale APGAR et le questionnaire d'auto-conception ont été employés pour recueillir des données auprès de 299 répondants à l'aide d'une technique d'échantillonnage systématique. Un SPSS (version 21) a été utilisé pour l'analyse.
Résultats de l'étude: Les résultats ont révélé que la majorité (82,9%) des répondants était entièrement immunisée et que 98% avaient des connaissances sur la vaccination. La majorité des répondants (85,6%) étaient issus de familles fonctionnelles. La fonctionnalité de la famille était statistiquement significative sur le statut vaccinal (X2 = 101,694, P = 0,000) ainsi que sur certaines composantes de la structure familiale: type de famille (P = 0,000), taille de la famille (P = 0,000), groupe ethnique (P = 0,000), et nombre d'enfants (P = 0,000)Conclusion: Les répondants avaient une connaissance adéquate de la vaccination. De plus, la fonctionnalité familiale et la structure familiale influencent le statut vaccinal des nourrissons. Par conséquent, d'autres études devraient être menées sur l'influence de la fonctionnalité et de la structure de la famille sur le statut vaccinal en utilisant une approche multicentrique.
Mots-clés: Immunisation, fonctionnalité familiale, structure familiale, vaccine
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Barroso Martínez, Ascensión, Ramón Sanguino Galván, and Tomas M. Bañegil Palacios. "El enfoque basado en el conocimiento en las empresas familiares." Investigación Administrativa 41-1 (January 1, 2012): 1–8. http://dx.doi.org/10.35426/iav41n109.05.
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Aunque algunas investigaciones sobre gestión del conocimiento se han centrado en las pequeñas y medianas empresas, existen escasos trabajos centrados en las empresas familiares. Las prácticas de gestión del conocimiento son una fuente importante de ventaja competitiva, que permiten a una organización ser innovadora. Estudios anteriores muestran que una de las causas del fracaso de las empresas familiares es la falta de voluntad de los miembros de la familia para crear y transferir conocimientos entre generaciones. Por ello, este trabajo se centra en el estudio de la estrategia basada en conocimiento (EBC) en las empresas familiares. Como conclusión, la gestión del conocimiento es considerado un activo estratégico clave que puede estar positivamente asociado con mayores niveles de rendimiento.
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Olopade, Olufunmilayo. "A family-based approach to primary prevention of breast cancer." Journal of Clinical Oncology 27, no. 15_suppl (May 20, 2009): s2. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.s2.
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s2 We are currently focusing on the interplay of genes and environment in the development of estrogen receptor (ER)-negative breast cancer, which is aggressive, less responsive to treatment, and more likely to strike young women and those of African ancestry. Unfortunately, there are no strategies to prevent ER-negative breast cancer and research is urgently needed. Nevertheless, we have made progress in understanding genetic risk factors for some familial forms of breast cancer, which is reason enough to adopt family-based interventions for breast cancer prevention, especially among families with identifiable highly penetrant mutations in breast cancer susceptibility genes. In 1997, I chaired the ASCO Task Force on Cancer Genetics Education, charged to educate oncologists about the importance of genetics in clinical oncology practice. Since then, a growing body of evidence documents the benefits of preventive measures with minimal risk to women with identifiable highly penetrant mutations in BRCA1 and BRCA2 genes. Whereas other genes, such as TP53 in Li-Fraumeni Syndrome and PTEN in Cowden syndrome, contribute to a small fraction of hereditary breast cancer, mutations in these genes are rare. Germ-line mutations in BRCA1 or BRCA2 are strong predictors of breast and/or ovarian cancer development, and the contribution of these mutations to breast cancer risk within any specific population is a function of both their prevalence and penetrance. Mutation prevalence varies among ethnic groups and may be influenced by founder mutations as observed in Ashkenazi Jews and Icelanders. Although estimates of mutation prevalence and penetrance rates are inconsistent and occasionally controversial, understanding them is critical for providing individualized risk assessment. Although the contribution of other genes to early onset and familial breast cancer needs clarification, genetic testing for BRCA1 and BRCA2 has become standard of care and an important component of personalized breast cancer risk assessment and prevention.
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Hoeeg, Didde, Dan Grabowski, and Ulla Christensen. "Intra-familial stigmatization." Health Education 118, no. 3 (April 3, 2018): 227–38. http://dx.doi.org/10.1108/he-10-2017-0056.
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Purpose To treat childhood obesity, health education interventions are often aimed at the whole family. However, such interventions seem to have a relatively limited effect on weight loss. The purpose of this paper is to examine how families enrolled in a family-based health education intervention manage the intervention in their daily lives and to understand how and why intra-familial conflicts may occur. Design/methodology/approach Data consist of 10 in-depth semi-structured family interviews with 25 family members (10 children, 15 parents), who were enrolled in a family-based health education intervention for families with an obese child. Findings Actively involving all family members in the intervention proved difficult in many families. Often, the children experienced inconsistent family support, which led to intra-familial conflicts. When parents were unsuccessful in changing unhealthy habits, the responsibility for healthy living was often passed on to the obese child. Thus, several families managed the intervention by making specific rules that only the obese child was required to adhere to. This resulted in several children feeling stigmatized in their own family. Practical implications Professionals working with family-based health education interventions should understand that, in order to minimize the risk of intra-familial conflicts and stigmatization of the obese child, all family members must be equally committed to the lifestyle intervention. Originality/value The study contributes to the existing literature by adding specific knowledge about how and why conflicts occur in these families and what the consequences of these conflicts are.
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BUCIUCEANU-VRABIE, Mariana, Nina MEŠL, Nevenka ZEGARAC, and Tadeja KODELE. "Skills in family support: content analysis of International Organizations’ Websites." Revista Calitatea Vieții 34, no. 1 (2023): 15–32. http://dx.doi.org/10.46841/rcv.2023.01.02.
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The study is part of a comprehensive research project launched within the framework of COST Action “The pan-European Family Support Network: A bottom-up, evidence-based and multidisciplinary approach” (EurofamNet, code CA18123). In this project, an exercise of mapping international organizations on skills qualification in family support has been developed. The aim of this study was to examine the profile of organizations and analyze their web-provided content to identify, describe and catalogue available data on basic professional skills, promoted, developed, and applied in family support work. The final sample includes 88 international and European organizations working with families with children and youth in various fields (psychology, social work, health, law, etc.) identified by the snowball technique. Using the method of web-content analysis three interconnected maps of bodies in the field were developed, highlighting a general profile of the organizations, and a wide range of important professional skills of family support workforce were specified and ranked. Frequency analyses and contingency tables were carried out. The results show that most of the organizations in the field do not present a plain definition of skills framework listed generally or in a separate document; multidisciplinary approaches to family support skills are not yet common practice; and evaluations of skills or references to a standard framework are limited. Keywords: family support; skills; family support workforce; standards; content analysis. Studiul face parte dintr-un proiect de cercetare de anvergură, lansat în cadrul acțiunii COST – „Rețeaua pan-Europeană de suport pentru familie„ (EurofamNet, cod 18123). În cadrul acestui proiect a fost dezvoltat un exercițiu de cartografiere a organizațiilor internaționale privind calificarea competențelor celor care activează în domeniul suportului familial. Scopul acestui studiu a fost de a examina profilul organizațiilor și de a analiza conținutul paginilor lor de web, pentru a identifica, descrie și cataloga datele disponibile despre competențele (skill[1]urile) profesionale de bază, promovate, dezvoltate și aplicate în cadrul muncii de suport pentru familie. Eșantionul final cuprinde 88 de organizații internaționale și europene ce lucrează cu familiile cu copii și tineri din diverse domenii (psihologie, asistență socială, sănătate, drept etc.), identificate prin tehnica bulgărelui de zăpadă. Folosind metoda analizei de conținut a paginilor de web au fost elaborate trei hărți interconectate a organizațiilor din domeniu, punând în evidență profilul lor general, precum și o gamă largă de skill-uri profesionale importante ale forței de muncă de suport familial a fost specificată și ierarhizată. Rezultatele arată că majoritatea organizațiilor din domeniu nu prezintă o definiție clară a unui cadru de competențe nici la modul general nici separat; abordarea multidisciplinară a competențelor profesionale (skill-uri) de suport familial nu sunt încă o practică comună; evaluările skill-urilor sau referința la un cadru standard sunt limitate. Cuvinte-cheie: suport pentru familie; competențe (skill-uri); forța de muncă pentru suportul familiei; standarde; analiza de conținut.
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Wilcken, D. E. L., B. L. Blades, and N. P. B. Dudman. "A neonatal screening approach to the detection of familial hypercholesterolaemia and family-based coronary prevention." Journal of Inherited Metabolic Disease 11, S1 (March 1988): 87–90. http://dx.doi.org/10.1007/bf01800573.
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Lynch, Patrick M. "Current Approaches in Familial Colorectal Cancer: A Clinical Perspective." Journal of the National Comprehensive Cancer Network 4, no. 4 (April 2006): 421–30. http://dx.doi.org/10.6004/jnccn.2006.0034.
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Individuals with a family history of colorectal cancer or colorectal adenomas have an increased risk for colorectal cancer. When no hereditary syndrome is evident, screening is based on empiric risk estimates. The risk is greatest for individuals with specific inherited cancer-predisposing disorders. When conditions such as familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer are diagnosed, specific neoplasm risk estimates can usually be performed based on advances in molecular genetics. These estimates lead to more straightforward and cost-effective approaches to surveillance and management. The National Comprehensive Cancer Center Network (NCCN) and other groups have provided detailed guidelines for evaluating patients based on recognition of clinical syndrome characteristics, followed by appropriate genetic counseling, genetic testing, and optimal surveillance. The NCCN guidelines are used as a frame of reference for this discussion of selected recent advances in human cancer genetics as they apply to clinical practice.
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Jermias, Emanuel Omedetho, Mauliadi Ramli, and Abdul Rahman. "Familisme dalam Manajemen Rumah Makan Sederhana di Kota Makassar." Ideas: Jurnal Pendidikan, Sosial, dan Budaya 9, no. 1 (February 14, 2023): 79. http://dx.doi.org/10.32884/ideas.v9i1.1151.
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The Micro, Small and Medium Enterprises sector, including simple restaurant business activities in Makassar City, contributes to the economy. This study aims to reveal the management of family-based restaurants and their implications for creating wealth, especially within the family environment. The method used in answering the research objectives, then carried out observations, interviews, and document studies. The results of the study show that restaurant owners prefer to recruit employees from family and relatives based on the moral economy approach. The selection of employees with a moral economy approach for restaurant owners is intended so that these employees can obtain a more prosperous level of economic life and a more proper education.
Dissertations / Theses on the topic "Approche familiale (Family-based)"
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Costantino, Félicie. "Recherche de nouveaux facteurs génétiques de susceptibilité à la spondyloarthrite grâce à une approche associant études familiales et génomique fonctionnelle." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05T056/document.
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La spondyloarthrite (SpA) est un rhumatisme inflammatoire chronique fréquent et invalidant. Plus d’une vingtaine de locus de susceptibilité à la maladie ont été identifiés à ce jour, dont HLA-B27 situé dans le complexe majeur d’histocompatibilité (CMH). L’objectif de ce travail était d’identifier de nouveaux facteurs génétiques de susceptibilité à la SpA grâce à une double approche d’études familiales et de génomique fonctionnelle. Dans la première partie, nous avons génotypé des familles multiplex de SpA. L’analyse de liaison non paramétrique a révélé la présence, en plus du CMH, d’un nouveau locus significativement lié à la SpA en 13q13. L’étude de ce locus nous a permis de restreindre la région d’intérêt à un intervalle de 1,3 Mb, dont le séquençage est en cours. Par ailleurs, l’étude d’association intra-familiale a identifié un SNP intronique de MAPK14 significativement associé à la SpA. Enfin, nous avons montré que l’un des SNPs du gène IL23R connu pour être associé à la spondylarthrite ankylosante était en fait associé à la présence d’une sacro-iliite radiologique dans la SpA. Parallèlement aux études familiales, nous avons comparé le transcriptome de cellules dendritiques de neuf patients atteints de SpA à celui de dix témoins sains. Nous avons ainsi identifié 81 gènes différentiellement exprimés. Nous avons aussi montré que l’expression génique d’ERAP1 (et à un moindre degré son expression protéique et son niveau d’activité enzymatique) étaient sous le contrôle de polymorphismes de ce gène associés à la SpASpondyloarthritis (SpA) is a frequent and disabling chronic rheumatic disease. To date, more than 20 susceptibility loci have been identified, including HLA-B27 in the major histocompatibility complex (MHC). Most of the disease heritability remains to be elucidated. The aim of the study was to identify new genetic factors of susceptibility to SpA using an approach combining genetics and functional genomics. In the first part of this work, we genotyped SpA multiplex families with microarrays of 250,000 SNPs. Non parametric linkage analysis revealed a new locus significantly linked to SpA outside the MHC, in 13q13. Further studies on this locus allowed us to map the disease interval to a 1.3 Mb region, which will be soon sequenced. Moreover, family-based association study identified a significant association between one intronic SNP in MAPK14 and SpA. We also showed that one of the known ankylosing spondylitis-associated SNP in IL23R was indeed associated with sacroiliitis in SpA. We have also compared dendritic cells gene expression between nine SpA patients and ten controls and identified 81 genes differentially expressed. Moreover, we showed that ERAP1 gene expression (and at a less extent protein expression and enzymatic activity) is under the control of several polymorphisms in the gene which has previously been associated with SpA
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Gzara, Chaïma. "Génétique humaine de la lèpre au Vietnam : une histoire de familles." Electronic Thesis or Diss., Université Paris Cité, 2021. http://www.theses.fr/2021UNIP5234.
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La lèpre, maladie infectieuse chronique causée par Mycobacterium leprae, affecte principalement la peau, les nerfs et les yeux avec des séquelles majeures en l’absence de traitement. Avec 200 000 nouveaux cas diagnostiqués chaque année (1 toutes les 2 minutes), il s’agit de la mycobactériose la plus commune après la tuberculose et requalifiée « maladie tropicale négligée » en 2017 par l’Organisation Mondiale de la Santé (OMS). Si la contribution génétique de l’hôte dans l’histoire naturelle de la maladie est maintenant bien établie, son architecture reste lacunaire. Dans cette continuité et afin de la préciser, nous avons, pour la première fois, utilisé une approche de génétique épidémiologique familiale. Plus précisément, nous avons réalisé la première étude d’association pangénomique (Genome-Wide Association Study, GWAS) familiale sur la lèpre. Ainsi, au cours des 20 dernières années, un échantillon de 481 familles nucléaires, parents et enfants, sélectionnées à partir d’un enfant atteint, a été constitué au Vietnam. Sur cet échantillon primaire de 1749 individus incluant 622 enfants atteints, nous avons testé l’association de près de 6 millions de variants bi-alléliques (Single Nucleotide Polymorphism, SNP), génotypés ou imputés, avec la lèpre. Dans un second temps, nous avons testé les signaux les plus prometteurs dans un échantillon de réplication, c’est-à-dire, indépendant et issu de la même population, constitué de 1 181 cas et 668 contrôles. Les résultats les plus significatifs ont été observés au sein de la région HLA et l’analyse multivariée a permis d’identifier trois signaux indépendants. Deux dans la région HLA classe I : rs1265048 [Odds-ratio (OR) = 0,69 ; p-val = 5,5.10⁻¹¹] et rs114598080 [OR = 1,47 ; p-val = 8,8.10⁻¹³] ; Et un dans la région HLA classe II : rs3187964 [OR = 1,67 ; p-val = 8,4.10⁻¹⁶]. Nous avons également identifié deux signaux hors HLA : un variant faux-sens dans le gène LACC1 (rs3764147 : OR = 1,52 ; p-val = 5,1.10⁻¹⁴), et un variant à proximité du gène IL12B (rs6871626 : OR = 0,73 ; p-val = 6.4.10⁻⁸). Les contraintes de coûts des études pangénomiques imposent une réduction majeure du nombre de SNPs à tester dans d’autres échantillons. Dans les études familiales, les parents sont de fait génotypés et pourraient permettre une réplication immédiate sans coûts ajoutés. Au moyen d’une large étude de simulation, nous avons montré que cette approche était pertinente. Une étude cas-contrôle chez les parents de l’échantillon primaire est une réplication valide, statistiquement indépendante de l’étude d’association familiale. C’est un argument fort en faveur des approches familiales pour l’exploration pangénomique de la contribution génétique de l’hôte dans les phénotypes complexes. La compréhension de la physiopathologie de l'infection à M. leprae est cruciale pour optimiser les approches préventives selon les profils génétiques à plus haut risque, et ouvrir de nouvelles pistes thérapeutiques en précisant les cascades fonctionnelles pertinentes. En ce sens, la dissection du contrôle génétique de l'infection par l'hôte est indispensable. Enfin, remettre la famille au cœur de la quête génétique, c’est remettre la génétique dans son milieu naturelLeprosy is a chronic infectious disease caused by Mycobacterium leprae. It primarily affects the skin and peripheral nerves, and can cause an irreversible impairment of nerve function, often leading to severe disabilities and social stigma if left untreated. The disease, re-qualified by WHO (World Health Organization) as a “Neglected Tropical Disease” in 2017, remains a major public health problem in regions of endemic countries, with over 200,000 new cases per year (one every two minutes). It is ranked second as the most common mycobacterial infectious disease, right after tuberculosis. While it has been well established that there is a genetic contribution to this disease, the underlying genetic causes remains unknown. In our study, we sought to reveal the host´s genetic architecture of leprosy by taking of a familial epidemiological approach. We conducted the first Family-Based Genome-Wide Association Study (GWAS) of leprosy in 481 Vietnamese nuclear families (parents and children) selected based on one affected child and collected over the past 20 years. Using this sample of 1,749 individuals, including 622 affected offspring, we performed association tests between six million biallelic genetic variants (Single-Nucleotide Polymorphism, genotyped or imputed) and the binary phenotype of disease status. Following this first analysis, we conducted a replication analysis of the most promising results in an independent sample of the same ethnic origin, accounting for 1,181 cases and 668 controls. The most significant results were observed within the HLA (Human Leukocyte Antigen) region, in which 3 independent SNPs displayed genome-wide significant associations. Among these, two were for the HLA class I region and one for the HLA class II (rs1265048 [OR = 0.69; p-value = 5.5x10⁻¹¹], rs114598080 [OR = 1.47; p-value = 8.8x10⁻¹³] and rs3187964 [OR = 1.67; p-value = 8.4x10⁻¹⁶] respectively). We also identified a missense variant in the LACC1 gene (rs3764147: OR = 1.52; p-value = 5.1x10⁻¹⁴) and an intergenic variant located close to the IL12B gene (rs6871626: OR = 0.73; p-value = 6.4x10⁻⁸). LACC1 encodes a central regulator of the metabolic function and bioenergetic state of macrophages and IL12B encodes IL-12p40, which is common to two interleukins, IL-12 and IL-23. Large GWAS are expensive, strongly limiting the number of variants to test in a replication set. Here, we took advantage of the available parental phenotypic and genotypic information to perform a classical case-control study among the parents of the family-based sample. Indeed, using of extensive computer simulations, we demonstrated that this population-based parental study is a valid, powerful and costless replication strategy to confirm family-based associations. Overall, our observations add to the attractiveness of family-based designs and should provide valuable help for investigators planning to perform GWA studies. Understanding leprosy pathophysiology infection is crucial to optimize preventive approaches based on genetic profiles. Dissection of the genetic control of the infection by M. leprae by its human host, therefore, constitutes an indispensable step. Finally, repositioning the family at the heart of the genetic quest means repositioning genetics into its natural environment
Books on the topic "Approche familiale (Family-based)"
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Berg, Insoo Kim. Services axés sur la famille: Une approche centrée sur la solution. Saint-Hyacinthe, Qué: Édisem, 1996.
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Berg, Insoo Kim. Family-based services: A solution-focused approach. New York: W.W. Norton, 1994.
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1913-, Bowen Murray, ed. Family evaluation: An approach based on Bowen theory. New York: Norton, 1988.
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1951-, Treat Stephen, ed. Couples in treatment: Techniques and approaches for effective practice. New York: Brunner/Mazel, 1992.
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1952-, Bograd Michele Louise, ed. Feminist approaches for men in family therapy. New York: Haworth Press, 1991.
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Treating Bulimia in Adolescents: A Family-Based Approach. Guilford Publications, 2009.
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Lock, James, and Daniel Le Grange. Treating Bulimia in Adolescents: A Family-Based Approach. Guilford Publications, 2007.
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Dare, Christopher, and James Lock. Treatment Manual for Anorexia Nervosa: A Family-Based Approach. The Guilford Press, 2000.
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Dodson, Laura Sue, and DeWayne J. Kurpius. Family Counseling: A Systems Approach. Taylor & Francis Group, 2013.
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Dodson, Laura Sue, and DeWayne J. Kurpius. Family Counseling: A Systems Approach. Taylor & Francis Group, 2013.
Find full textBook chapters on the topic "Approche familiale (Family-based)"
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Wilcken, D. E. L., B. L. Blades, and N. P. B. Dudman. "A Neonatal Screening Approach to the Detection of Familial Hypercholesterolaemia and Family-based Coronary Prevention." In Studies in Inherited Metabolic Disease, 87–90. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1259-5_8.
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Gonsalves, Edward, and Ricardo Zamora. "Ludens Familias." In Advances in Business Strategy and Competitive Advantage, 167–96. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-3171-6.ch009.
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Many business schools and other family business education providers have over the last 15 years been authoritatively criticised for a lack of innovation and adaptability in their pedagogical designs. The increasing economic participation of international family businesses in developed, developing, and emerging markets in the decade after the global financial crisis of 2008/9 has extended this critique. This chapter proposes a play-based response to such criticism and a pathway for ‘leaning into' the future demands of family business education (FBE). The authors suggest that a play-based approach re-dresses some of the above imbalances. The chapter draws on the development of an expansive, activity-based framework for playful learning designs. As an example of their approach, the authors use their method-based reconfiguration of traditional (family business) case-studies into live, ‘ludic objects' (RETS-MICA), to demonstrate ways in which and play affords MBA, family business learners the opportunity to build their entrepreneurial competencies in-situ.
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Smith, Howard L., and Kalpana Mukunda Iyengar. "Mi Familia." In Advances in Early Childhood and K-12 Education, 169–91. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-3955-1.ch009.
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This chapter discusses the results of a writing activity during Family Literacy Night at a predominantly Hispanic, Title I school in the Southwest. This study, based on Socio-Cultural Theory (Moll, 2013), demonstrates the efficacy of asset-based approaches for instruction and assessment versus more traditional deficit models of minority education. As an analytic, the researchers applied the six Capitals from the Community Cultural Wealth (CCW) model (Yosso, 2005) to the children's writing samples. This framework revealed a variety of strengths common to Latino and bilingual households including the metalinguistic skill of translanguaging. Data was processed through Holistic Content Analysis (Lieblich, 2005) followed by thematic analysis (Falk & Blumenreich, 2005) supported by CCW. Results underscore the importance of out-of-school literacies and their affective impact on children from underserved communities. Moreover, results argue for more home- and community-based writing assignments to reveal student values, desires, and emotions, which encourage the joy of writing.
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Emery, Clifton R., and Alhassan Abdullah. "Formal and Informal Social Control of Family Violence." In Psychological Perspectives on Understanding and Addressing Violence Against Children, edited by Tobias Hecker, Faustine Bwire Masath, Joseph Ssenyonga, Mabula Nkuba, and Katharin Hermenau, 253—C14.P116. Oxford University PressNew York, 2022. http://dx.doi.org/10.1093/med-psych/9780197649510.003.0014.
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Abstract When intimate partner violence (IPV) is deterred or completely avoided, children benefit by living in a more stable, secure familial environment free from violence. This chapter reviews the research literature, with a particular focus on the relationship between social control and IPV, organizing the literature on both formal and informal social control into protective and punitive subtypes. Restorative justice approaches are conceptualized as situated primarily within the protective subtype, but evidence suggests that they may merit their own subtype, termed restitute social control. Finally, the chapter argues that social control of IPV and family violence must be based on an appropriate understanding of the role of family heterogeneity in the trajectory of IPV and family violence.
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Fuentes, Jacqueline, Violeta J. Rodriguez, Madison L. Rodriguez, and Ana Carina Ordaz. "Juntos Resistimos y Sanamos." In Advances in Psychology, Mental Health, and Behavioral Studies, 211–27. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-6684-4901-1.ch012.
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The authors seek to provide a more holistic, compassionate, and liberatory understanding of Latinx families. This chapter will highlight the importance of understanding families from a historical, culturally centered manner that honors their layered experiences of contextual factors, intergenerational trauma, and strengths-based approach. This chapter seeks to honor ethnic heterogeneity and cultural strengths and expand the notion of what consists of the family constellation. In doing so, the chapter will focus on central aspects of la familia, including child development, parenting, and recommendations focused on engaging Latinx families and improving the assessment and family interventions.
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Cen-Yagiz, Suzan, and Berna Aytac. "An Ecocultural Perspective on Learning Disability: Evaluation of Familial and Cultural Factors and Presentation of an Integrated Model." In Dyslexia. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95827.
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Ecocultural theory defines culture as a broad context that includes the tasks, goals, beliefs, values, and resources of society. According to ecocultural theory, culture shapes families’ resources, routines, goals, and parenting practices. In turn, these characteristics of family ecology and parenting determine child development. Ecocultural theory is one of the modern approaches that examine the adaptation of children with disabilities and their families. This chapter aims to outline the relationship between cultural values and families’ support resources, and their influence on adaptation of the families and their children with learning disability (LD) within the framework of ecocultural theory. Previous studies supported that cultural values determine public knowledge, awareness, beliefs, and attitudes about LD. This chapter outlines both the detrimental and positive effects of the public knowledge, beliefs, and attitudes on families’ support resources. Also, families’ diversified support resources are detailed, and their differential influences on family and child development are elaborated. In the chapter, an integrated model is presented based on findings of previous empirical studies and ecocultural perspective. The model might enhance a culturally sensitive understanding of the experience of families and children. This chapter can also guide researchers in developing more comprehensive and effective intervention programs for the target group.
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Vanhuysse, Pieter, and Róbert Iván Gál. "Intergenerational Resource Transfers in the Context of Welfare States." In The Oxford Handbook of Family Policy, 1015—C47.P109. Oxford University Press, 2023. http://dx.doi.org/10.1093/oxfordhb/9780197518151.013.48.
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Abstract The main focus of the chapter is on “inter-age transfer,” or the resources reallocated among different age groups at a given moment in time. The welfare state is, in fact, primarily an inter-age, rather than an inter-class, redistribution vehicle. The chapter introduces a new approach to the measurement of such inter-age transfers that includes, besides welfare state public transfers and market-based private transfers, the transfer of unpaid household labor within the family ( time). The chapter uses a recently developed methodology, National Transfer Accounts (henceforth NTA) and National Time Transfer Accounts (henceforth NTTA), that includes familial transfers of money and of time into the calculation of the amount of inter-age transfers in a society. It shows that, once all three transfer types are taken into account, Europe proves to be a continent of elderly-oriented welfare states embedded within societies composed of strongly child-oriented families. By comparing the inter-age transfer systems of Sweden and Taiwan, the authors show that their overall transfer burdens are surprisingly similar.
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Hagège, Albert Alain. "Hypertrophic cardiomyopathy: diagnosis and assessment of symptoms." In ESC CardioMed, 1450–55. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0351.
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The diagnosis of hypertrophic cardiomyopathy (HCM) in adults is based on the presence of left ventricular wall thickness greater than 15 mm using any imaging modality on at least one myocardial segment and not explained solely by abnormal cardiac loading conditions; a 13 mm threshold should be applied for familial screening in first-degree relatives. Diagnosis in children, in the elderly, in hypertensive individuals, and in elite athletes may be challenging. Initial evaluation should include a family pedigree, evaluation of signs and symptoms, electrocardiogram, and 48 h Holter electrocardiogram monitoring, exercise testing, imaging, and biochemistry. The presence of an intraventricular left ventricular obstruction, present in two-thirds of the patients at rest, during Valsalva or exercise, should be systematically evaluated using echocardiography. Cardiovascular magnetic resonance imaging with late gadolinium enhancement should always be considered, particularly to assess apical hypertrophy, left ventricular aneurysms, and fibrosis. This systematic approach is recommended to assist in the detection of HCM not caused by mutations in cardiac sarcomere protein genes (up to 10% of patients). Genetic tests should be performed and interpreted after a careful and complete clinical evaluation and genetic counselling. HCM is characterized by symptoms of dyspnoea, fatigue, chest pain, palpitations, and syncope, which are highly variable. Functional limitation may be difficult to evaluate and often necessitates cardiopulmonary exercise testing.
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Hagège, Albert Alain. "Hypertrophic cardiomyopathy: diagnosis and assessment of symptoms." In ESC CardioMed, 1450–55. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0351_update_001.
Full textAbstract:
The diagnosis of hypertrophic cardiomyopathy (HCM) in adults is based on the presence of left ventricular wall thickness greater than 15 mm using any imaging modality on at least one myocardial segment and not explained solely by abnormal cardiac loading conditions; a 13 mm threshold should be applied for familial screening in first-degree relatives. Diagnosis in children, in the elderly, in hypertensive individuals, and in elite athletes may be challenging. Initial evaluation should include a family pedigree, evaluation of signs and symptoms, electrocardiogram, and 48 h Holter electrocardiogram monitoring, exercise testing, imaging, and biochemistry. The presence of an intraventricular left ventricular obstruction, present in two-thirds of the patients at rest, during Valsalva or exercise, should be systematically evaluated using echocardiography. Cardiovascular magnetic resonance imaging with late gadolinium enhancement should always be considered, particularly to assess apical hypertrophy, left ventricular aneurysms, and fibrosis. This systematic approach is recommended to assist in the detection of HCM not caused by mutations in cardiac sarcomere protein genes (up to 10% of patients). Genetic tests should be performed and interpreted after a careful and complete clinical evaluation and genetic counselling. HCM is characterized by symptoms of dyspnoea, fatigue, chest pain, palpitations, and syncope, which are highly variable. Functional limitation may be difficult to evaluate and often necessitates cardiopulmonary exercise testing.
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Kiddey, Rachael. "Conclusion." In Homeless Heritage. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198746867.003.0014.
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An archaeological approach to contemporary homelessness contributes to existing literature on the subject by materializing this familiar yet alien social status in a number of ways. Globally, homelessness continues to suffer from being conceptually constructed according to essentially British nineteenth-century ideologies that are class-based and heavily gendered, whilst, increasingly commonly, manifesting physically as a diverse and phenomenological experience. Approaching homelessness using participatory cultural heritage methodologies enabled those involved in the Homeless Heritage project to collectively destabilize some of the pernicious myths that surround homelessness, present alternative perspectives, and identify practical ways in which homeless people might be better helped to survive and recover. Positive outcomes from the Homeless Heritage project include the ways in which people involved experienced increased social connectedness and enhanced well-being. Homeless colleagues actively chose to (re)engage with existing social and public services with more robust commitment than had previously been the case, while reconnecting with family also emerged as a strong and important outcome from the Homeless Heritage project. There were theoretical implications too. Where archaeology may be considered an ‘intervention’—a methodology for engaging with the material world— heritage is the human context by which such engagement is made possible. Heritage, a mode of cultural production, has an important role to play in facilitating redemptive and cathartic conversations about difficult or distressing human experiences and could powerfully affect the course of social policies in the future. Conversations facilitated through Applied Heritage can produce more nuanced understanding, which could feasibly be used to improve and enhance social justice on local levels and promote tolerance, understanding, and peace on the wider international stage. The initial aim of the project was to see whether an archaeological cultural heritage approach to contemporary homelessness might contribute to wider understanding of the social condition. A significant outcome was a more nuanced understanding of homelessness in the twenty-first century. This helped to powerfully counter definitions and rationalizations of homelessness in terms of nineteenth-century constructions of vagrancy. A more surprising outcome concerns evidence that Applied Heritage can function as a powerful therapeutic form of social intervention. In approaching homelessness archaeologically, from the perspective of a range of individual agents, the Homeless Heritage project clearly showed why a homeless person might ‘choose’ to appropriate, for example, space beneath a willow tree or a bin cupboard over conditions in temporary accommodation deemed ‘suitable’ for statutorily homeless people.
Conference papers on the topic "Approche familiale (Family-based)"
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Devendorf, Margaret, and Kemper Lewis. "Designing a Product Package Platform." In ASME 2010 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/detc2010-28888.
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An essential part of designing a successful product family is establishing a recognizable, familiar, product family identity. It is very often the case that consumers first identify products based on their physical embodiment. The Apple iPod, DeWalt power tools, and KitchenAid appliances are all examples of product families that have successfully branded themselves based on physical principles. While physical branding is often the first trait apparent to designers, there are some products that cannot be differentiated based on physical appearance. This is especially common for consumable products. For example, it is impossible to differentiate between diet Coke, Classic Coke, and Pepsi when each is poured into separate glasses. When differentiation is difficult to achieve from a product’s physical characteristics, the product’s package becomes a vital part of establishing branding and communicating membership to a product family while maintaining individual product identity. In this paper, product packaging is investigated with a focus on the graphic packaging components that identify product families. These components include: color, shape, typography, and imagery. Through the application of tools used in facilities layout planning, graph theory, social network theory, and display design theory an approach to determine an optimal arrangement of graphic components is achieved. This approach is validated using a web based survey that tracks user-package interactions across a range of commonly used cereal boxes.
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Goetz, Stefan, Benjamin Schleich, and Sandro Wartzack. "CAD-Based Tolerance Analysis in Preliminary Design Stages Enabling Early Tolerance Evaluation." In ASME 2018 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/imece2018-86396.
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Associated with manufacturing and assembly processes, inevitable geometric deviations have a decisive influence on the function and quality of products. Therefore, their consideration and management are important tasks in product development. Moreover, to meet the demand for short development times, the front-loading of design processes is indispensable. This requires early tolerance analyses evaluating the effect of deviations in a design stage, where the product’s geometry has not yet been finally defined. Since such an early tolerance consideration allows quick and economic design changes seeking for robust designs, it is advisable that the design engineer, who is entirely familiar with the design, should take this step. For this purpose, this paper presents an easy-to-use CAD-based tolerance analysis method for skeleton models. The relevant part deviations are represented by varying geometric dimensions with externally driven family tables. The approach comprises the strength of vector-based methods but does not require an expensive set-up of tolerance analysis models. Particularly, the novelty of this method lies in the CAD-internal sampling-based tolerance analysis of simple geometries without the use of expensive CAT software. This enables designers to evaluate the effect of tolerances already at the preliminary design stage. Using a case study, the presented approach is compared with the conventional vector-based tolerance analysis.
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Pasetto, Camila Vitola, Diego Wallace Nascimento, Gabriela Bezerra Nóbrega, and José Roberto Filassi. "AXILLARY ACCESSORY BREAST SARCOMA IN A YOUNG PATIENT." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1007.
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The accessory breast tissue in the axillary region is rare, but as there is breast tissue, there is the possibility of pathological degeneration. With an even greater rarity, breast sarcoma is a diverse group of malignancies derived from mesenchymal tissues. The aim of this report was to describe a case of a young patient with sarcomatous neoplasia in the axillary accessory breast topography. Patient LPMS, 19 years old, female, admitted to the mastology service of the Hospital das Clínicas of the Universidade de São Paulo with a nodule realized in the left axillary region with progressive growth during pregnancy. The patient was healthy with a family history of a maternal aunt with breast cancer at 50 years old. At the clinical examination, she had an extensive tumor affecting the left axillary region measuring 10 cm with clinically negative axilla. Contralateral breast and axilla and supra-/infraclavicular fossas without abnormalities. In the initial mammogram, a hyperdense, oval, and indistinct nodule was found in the left axillary extension, measuring 10.8 cm. In breast magnetic resonance imaging, a heterogeneous mass in the left axillary extension is observed with irregular, lobulated margins, measuring 10.3×10×10.1 cm, heterogeneously and concentric by the contrast. Core biopsy was performed with the result of spindle cell mesenchymal neoplasm. In the systemic staging examinations, there was no evidence of a lesion suspected of distant metastasis. Vincristine 1.5 mg/m2 + Actinomycin D 0.45 mg/kg/day + Cyclophosphamide were prescribed to the patient. After six cycles with no clinical response, it was decided to switch the neoadjuvant chemotherapy to doxorubicin 25 mg/m2 and Ifosfamide 3,000 mg/m2 . After three cycles, the patient remains without a clinical response to neoadjuvant chemotherapy. It was decided to refer the patient to radiotherapy for axillary irradiation on the right, with a subsequent surgical approach. The patient underwent surgery with wide resection of the tumor and axillary lymph nodes. The anatomopathological examination showed sarcoma with immunohistochemistry suggestive of rhabdomyosarcoma measuring 19.3×14.8×14.7 mm with free margins and with sarcoma metastasis in one of the 21 dissected lymph nodes. The patient progresses well postoperatively. Accessory breast tissue has a very rare incidence in the population, with incidence rates of 1–2%. With regard to breast sarcoma, it is a very rare condition. It consists of a heterogeneous group of nonepithelial tumors originating from the mesenchymal tissues of the breast. They account for <1% of all breast malignancies and <5% of all sarcomas. Due to its rarity, current knowledge about breast sarcoma is limited and is mainly based on small retrospectives, case series, or case reports. Angiosarcoma, including secondary angiosarcoma from before breast radiation, is the most frequent type of breast sarcoma. As with other soft-tissue sarcomas, the primary breast sarcoma is associated with genetic conditions such as Li-Fraumeni syndrome, familial adenomatous polyposis, and type 1 neurofibromatosis. Therefore, breast sarcoma treatment generally follows the algorithms derived from trials of soft-tissue sarcomas in the chest wall, as has been done with the reported patient. Surgical treatment is the standard and most accepted treatment for breast sarcoma. The role of chemotherapy for breast sarcoma is also uncertain. There are no prospective studies that specifically assess the benefit of chemotherapy in adjuvant or neoadjuvant settings. Likewise, the benefit of radiotherapy in breast sarcoma is also very doubtful with evidence of benefit in large tumors and with positive margins after surgical resection.