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1

Augustin, Goran. Acute appendicitis in pregnancy. Hauppauge, N.Y: Nova Science Publishers, 2010.

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2

L, Krähenbühl, ed. Acute appendicitis: Standard treatment or laparoscopic surgery? Basel: Karger, 1998.

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3

KEYZER, Caroline, and Pierre Alain Gevenois, eds. Imaging of Acute Appendicitis in Adults and Children. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-17872-6.

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4

Medical Research Council. Environmental Epidemiology Unit., ed. The aetiology of acute appendicitis: Proceedings of a meeting held on 22nd May 1986 at the MRC Environmental Epidemiology Unit. Southampton: Southampton General Hospital, 1986.

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5

Catanzaro, Michael P., and Rachel J. Kwon. Acute Appendicitis. Edited by Rachel J. Kwon. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199384075.003.0049.

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This chapter provides a summary of a landmark historical study in surgery involving management and treatment of acute appendicitis. It describes the history of the disease, gives a summary of the study including study design and results, and relates the study to a modern-day principle of evidence-based medicine: observational studies in study design. Reginald H. Fitz’s insights over a century ago in a seminal case series regarding the nature of appendicitis, its potential sequelae, and the value of urgent surgical intervention changed the disease from a deadly one into one that can be easily cured by surgery. However, with the advent of modern broad spectrum antibiotic therapy, Fitz’s assertion that immediate surgical therapy is always mandated has recently come under question.
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6

Beattie, Mark, and Mike Stanton. Acute abdominal pain. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198759928.003.0041.

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7

Beattie, R. Mark, Anil Dhawan, and John W.L. Puntis. Acute abdominal pain. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569862.003.0036.

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Introduction 252Appendicitis 253Intussusception 253Miscellaneous conditions 254The commonest surgical diagnosis in children who present to hospital with acute abdominal pain is appendicitis. The differential diagnosis is wide, however (see box below), and in >50% of admissions no specific cause is found....
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8

Kr�henb�hl, L., E. Frei, C. Klaiber, and M. W. B�chler, eds. Acute Appendicitis: Standard Treatment or Laparoscopic Surgery? S. Karger AG, 1998. http://dx.doi.org/10.1159/isbn.978-3-318-00270-6.

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9

Lee, Christoph I. Multidetector CT for Acute Appendicitis in Adults. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190223700.003.0027.

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This chapter, found in the abdominal and pelvic pain section of the book, provides a succinct synopsis of a key study examining the use of multidetector computed tomography for diagnosing acute appendicitis in adults. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. This technique was shown to reduce rates of perforation and negative findings at appendectomy when incorporated into routine diagnostic algorithms, and can redirect management for patients with alternative diagnoses. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.
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10

Guttadauro, Angelo. Doubts, Problems and Certainties about Acute Appendicitis. Intechopen, 2022.

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11

Gevenois, Pierre Alain, and Caroline KEYZER. Imaging of Acute Appendicitis in Adults and Children. Springer, 2016.

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12

Gevenois, Pierre Alain, and Caroline KEYZER. Imaging of Acute Appendicitis in Adults and Children. Springer, 2011.

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13

Imaging Of Acute Appendicitis In Adults And Children. Springer, 2011.

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14

Scordino, David. Appendicitis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199976805.003.0036.

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Appendicitis is caused by acute inflammation of the appendix (usually secondary to obstruction) and can result in perforation, leading to peritonitis, sepsis, and/or abscess formation. Symptomatology includes anorexia, nausea, vomiting, and periumbilical pain (later localizing to the right lower quadrant). Patients at the extremes of age and pregnant women may have atypical presentations and higher rates of perforation and complications. Most patients suspected of having appendicitis receive prompt surgical intervention (usually laparoscopic). Antibiotic therapy, initiated preoperatively, varies for perforated vs nonperforated appendicitis. In patients with evidence of a contained abscess, nonoperative therapy is considered, as abscess is evidence of a prolonged disease course (more than 5 days) prior to presentation. On imaging, patients may have a well-circumscribed abscess or phlegmon; if immediate surgical intervention is attempted, there is significant risk of morbidity due to adhesions to adjacent tissues.
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15

Doubts, Problems and Certainties about Acute Appendicitis [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.91502.

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16

Stacey, Victoria. Surgery. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199592777.003.0006.

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The acute abdomen - Biliary tract disorders - Acute pancreatitis - Appendicitis - Bowel obstruction - Bowel perforation - Bowel ischaemia/infarction - Abdominal aortic aneurysm - Aortic dissection - Acute limb ischaemia - Haematuria - Renal colic - Urinary tract infections - Testicular torsion - Priapism - Fournier’s gangrene - SAQs
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17

Garbuzenko, Dmitry Victorovich, ed. Current Issues in the Diagnostics and Treatment of Acute Appendicitis. InTech, 2018. http://dx.doi.org/10.5772/intechopen.70917.

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18

Garbuzenko, Dmitry Victorovich. Current Issues in the Diagnostics and Treatment of Acute Appendicitis. IntechOpen, 2018.

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19

Kwon, Rachel J. Laparoscopic versus Open Appendectomy. Edited by Danny Sherwinter and Miguel A. Burch. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199384075.003.0036.

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This chapter provides a summary of a landmark study in minimally invasive surgery. Compared with open appendectomy, does laparoscopic appendectomy for acute appendicitis offer any advantage with respect to recovery, complications, or return to normal activities? Starting with that question, it describes the basics of the study, including year study was published, study location, who was studied, who was excluded, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, gives a summary and discusses implications, and concludes with a relevant clinical case involving laparoscopic appendectomy for a patient with acute appendicitis.
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20

Lee, Christoph I. Imaging Appendicitis in Children. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190223700.003.0025.

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This chapter, found in the abdominal and pelvic pain section of the book, provides a succinct synopsis of a key study examining the use of ultrasound and computed tomography (CT) among children with suspected appendicitis. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. The study showed that CT with contrast after a negative or indeterminate pelvic ultrasound leads to very high accuracy in diagnosing acute appendicitis in children. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.
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21

Gardiner, Matthew D., and Neil R. Borley. Emergency surgery. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199204755.003.0008.

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This chapter begins by discussing the basic principles of Advanced Trauma Life Support, care of the critically ill surgical patient, shock, SIRS and sepsis, and blood products and transfusion, before focusing on the key areas of knowledge, namely traumatic head injury, spine and spinal cord trauma, maxillofacial trauma, cardiothoracic trauma, abdominal trauma, urological trauma, vascular trauma, assessment of the acute abdomen, acute appendicitis, acute upper gastrointestinal haemorrhage, lower gastrointestinal haemorrhage, gastrointestinal obstruction, gastrointestinal perforation, acute pancreatitis, and superficial sepsis. The chapter concludes with relevant case-based discussions.
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22

Carton, James. Gastrointestinal pathology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198759584.003.0007.

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This chapter discusses gastrointestinal pathology, including gastrointestinal malformations, oesophagitis, oesophageal polyps and nodules, oesophageal carcinoma, gastritis, gastric polyps, gastric carcinoma, gastrointestinal stromal tumours, peptic duodenitis, coeliac disease, small bowel infarction, intestinal infections, intestinal obstruction, acute appendicitis, Crohn’s disease, ulcerative colitis, colorectal polyps, colorectal carcinoma, diverticular disease, and anal pathology.
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23

Krahenbuhl, L. Acute Appendicitis: Standard Treatment and the Role of Laparoscopic Surgery (Progress in Surgery). S. Karger Publishers (USA), 1998.

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24

Sohn, Woon-Mok, and Jong-Yil Chai. Anisakiosis (Anisakidosis). Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0070.

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The term ‘anisakiosis (anisakidosis)’ or ‘anisakiasis’ collectively defines human infections caused by larval anisakids belonging to the nematode family Anisakidae or Raphidascarididae. Anisakis simplex, Anisakis physeteris, and Pseudoteranova decipiens are the three major species causing human anisakiosis. Various kinds of marine fish and cephalopods serve as the second intermediate hosts and the infection source. Ingestion of viable anisakid larvae in the fillet or viscera of these hosts is the primary cause of infection. The parasite does not develop further in humans as they are an accidental host. Clinical anisakiosis develops after the penetration of anisakid larvae into the mucosal wall of the alimentary tract, most frequently the stomach and the small intestine. The affected sites undergo erosion, ulceration, swelling, inflammation, and granuloma formation around the worm. The patients may suffer from acute abdominal pain, indigestion, nausea, vomiting, and in some instances, allergic hypersensitive reactions. Symptoms in gastric anisakiosis often resemble those seen in peptic ulcer or gastric cancer, and symptoms in intestinal anisakiosis resemble those of appendicitis or peritonitis. Treatments include removal of larval worms using a gastroendoscopic clipper or surgical resection of the mucosal tissue surrounding the worm. No confirmed effective anthelmintic drug has been introduced, though albendazole and ivermectin have been tried in vivo and in vitro. Prevention of human anisakiosis can be achieved by careful examination of fish fillet followed by removal of the worms in the restaurant or household kitchen. Immediate freezing of fish and cephalopods just after catching them on fishing boats was reported helpful for prevention of anisakiosis. It is noteworthy that anisakiosis is often associated with strong allergic and hypersensitivity reactions, with symptoms ranging from isolated angioedema to urticaria and life threatening anaphylactic shock.
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25

S. Catello negli Acta Sanctorum. Con l'inedita Vita del santo redatta in italiano per gli AA. SS. nella prima metà del Seicento dai Gesuiti di Castellammare. Testi latini con traduzione a fronte. In Appendice: Francesco Rosso, Breve elogio sopra la Vita del Glorioso S. Catello ... Bibliotheca Stabiana, 2020.

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