Journal articles on the topic 'APP and amyloid fragments'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'APP and amyloid fragments.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
Yokota, Masayuki, Takaomi C. Saido, Eiichi Tani, Ikuya Yamaura, and Nobutaka Minami. "Cytotoxic Fragment of Amyloid Precursor Protein Accumulates in Hippocampus after Global Forebrain Ischemia." Journal of Cerebral Blood Flow & Metabolism 16, no. 6 (November 1996): 1219–23. http://dx.doi.org/10.1097/00004647-199611000-00016.
Chyung, Abraham S. C., Barry D. Greenberg, David G. Cook, Robert W. Doms, and Virginia M. Y. Lee. "Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells." Journal of Cell Biology 138, no. 3 (August 11, 1997): 671–80. http://dx.doi.org/10.1083/jcb.138.3.671.
Niederst, Emily D., Sol M. Reyna, and Lawrence S. B. Goldstein. "Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing." Molecular Biology of the Cell 26, no. 2 (January 15, 2015): 205–17. http://dx.doi.org/10.1091/mbc.e14-06-1049.
Lee, Ming-Sum, Shih-Chu Kao, Cynthia A. Lemere, Weiming Xia, Huang-Chun Tseng, Ying Zhou, Rachael Neve, Michael K. Ahlijanian, and Li-Huei Tsai. "APP processing is regulated by cytoplasmic phosphorylation." Journal of Cell Biology 163, no. 1 (October 13, 2003): 83–95. http://dx.doi.org/10.1083/jcb.200301115.
Feng, Fei, Yuanyuan Li, Nanqu Huang, and Yong Luo. "Icaritin, an inhibitor of beta-site amyloid cleaving enzyme-1, inhibits secretion of amyloid precursor protein in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway." PeerJ 7 (December 10, 2019): e8219. http://dx.doi.org/10.7717/peerj.8219.
Ghiso, J., A. Rostagno, J. E. Gardella, L. Liem, P. D. Gorevic, and B. Frangione. "A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion." Biochemical Journal 288, no. 3 (December 15, 1992): 1053–59. http://dx.doi.org/10.1042/bj2881053.
Cook, J. J., K. R. Wildsmith, D. B. Gilberto, M. A. Holahan, G. G. Kinney, P. D. Mathers, M. S. Michener, et al. "Acute -Secretase Inhibition of Nonhuman Primate CNS Shifts Amyloid Precursor Protein (APP) Metabolism from Amyloid- Production to Alternative APP Fragments without Amyloid- Rebound." Journal of Neuroscience 30, no. 19 (May 12, 2010): 6743–50. http://dx.doi.org/10.1523/jneurosci.1381-10.2010.
Yu, Yang, Yang Gao, Bengt Winblad, Lars O. Tjernberg, and Sophia Schedin-Weiss. "A Super-Resolved View of the Alzheimer’s Disease-Related Amyloidogenic Pathway in Hippocampal Neurons." Journal of Alzheimer's Disease 83, no. 2 (September 14, 2021): 833–52. http://dx.doi.org/10.3233/jad-215008.
Stieren, Emily S., Amina El Ayadi, Yao Xiao, Efraín Siller, Megan L. Landsverk, Andres F. Oberhauser, José M. Barral, and Darren Boehning. "Ubiquilin-1 Is a Molecular Chaperone for the Amyloid Precursor Protein." Journal of Biological Chemistry 286, no. 41 (August 18, 2011): 35689–98. http://dx.doi.org/10.1074/jbc.m111.243147.
Ono, Kenji, Mikio Niwa, Hiromi Suzuki, Nahoko Bailey Kobayashi, Tetsuhiko Yoshida, and Makoto Sawada. "Signal Sequence-Dependent Orientation of Signal Peptide Fragments to Exosomes." International Journal of Molecular Sciences 23, no. 6 (March 15, 2022): 3137. http://dx.doi.org/10.3390/ijms23063137.
Xie, Zhongcong, Yuanlin Dong, Uta Maeda, Weiming Xia, and Rudolph E. Tanzi. "RNA Interference Silencing of the Adaptor Molecules ShcC and Fe65 Differentially Affect Amyloid Precursor Protein Processing and Aβ Generation." Journal of Biological Chemistry 282, no. 7 (December 14, 2006): 4318–25. http://dx.doi.org/10.1074/jbc.m609293200.
Marttinen, Mikael, Catarina B. Ferreira, Kaisa M. A. Paldanius, Mari Takalo, Teemu Natunen, Petra Mäkinen, Luukas Leppänen, et al. "Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ." Cells 9, no. 11 (November 15, 2020): 2482. http://dx.doi.org/10.3390/cells9112482.
Hao, Candy Yan, Michael S. Perkinton, William Wai-Lun Chan, Ho Yin Edwin Chan, Christopher C. J. Miller, and Kwok-Fai Lau. "GULP1 is a novel APP-interacting protein that alters APP processing." Biochemical Journal 436, no. 3 (May 27, 2011): 631–39. http://dx.doi.org/10.1042/bj20110145.
Kuentzel, S. L., S. M. Ali, R. A. Altman, B. D. Greenberg, and T. J. Raub. "The Alzheimer β-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells." Biochemical Journal 295, no. 2 (October 15, 1993): 367–78. http://dx.doi.org/10.1042/bj2950367.
Ono, Kenji, Mikio Niwa, Hiromi Suzuki, Nahoko Bailey Kobayashi, Tetsuhiko Yoshida, and Makoto Sawada. "Calmodulin as a Key Regulator of Exosomal Signal Peptides." Cells 12, no. 1 (December 30, 2022): 158. http://dx.doi.org/10.3390/cells12010158.
Annaert, Wim G., Lyne Levesque, Kathleen Craessaerts, Inge Dierinck, Greet Snellings, David Westaway, Peter St George-Hyslop, Barbara Cordell, Paul Fraser, and Bart De Strooper. "Presenilin 1 Controls γ-Secretase Processing of Amyloid Precursor Protein in Pre-Golgi Compartments of Hippocampal Neurons." Journal of Cell Biology 147, no. 2 (October 18, 1999): 277–94. http://dx.doi.org/10.1083/jcb.147.2.277.
Cater, Michael A., Kelly T. McInnes, Qiao-Xin Li, Irene Volitakis, Sharon La Fontaine, Julian F. B. Mercer, and Ashley I. Bush. "Intracellular copper deficiency increases amyloid-β secretion by diverse mechanisms." Biochemical Journal 412, no. 1 (April 25, 2008): 141–52. http://dx.doi.org/10.1042/bj20080103.
Maarouf, Chera L., Tyler A. Kokjohn, Charisse M. Whiteside, MiMi P. Macias, Walter M. Kalback, Marwan N. Sabbagh, Thomas G. Beach, Robert Vassar, and Alex E. Roher. "Molecular Differences and Similarities between Alzheimer's Disease and the 5XFAD Transgenic Mouse Model of Amyloidosis." Biochemistry Insights 6 (January 2013): BCI.S13025. http://dx.doi.org/10.4137/bci.s13025.
Pang, Keliang, Richeng Jiang, Wei Zhang, Zhengyi Yang, Lin-Lin Li, Makoto Shimozawa, Simone Tambaro, et al. "An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments." Cell Research 32, no. 2 (November 17, 2021): 157–75. http://dx.doi.org/10.1038/s41422-021-00582-x.
Hajdú, István, Barbara M. Végh, András Szilágyi, and Péter Závodszky. "Beta-Secretase 1 Recruits Amyloid-Beta Precursor Protein to ROCK2 Kinase, Resulting in Erroneous Phosphorylation and Beta-Amyloid Plaque Formation." International Journal of Molecular Sciences 24, no. 13 (June 21, 2023): 10416. http://dx.doi.org/10.3390/ijms241310416.
Crino, Peter B., Barry Greenberg, John A. Martin, Virginia M. Y. Lee, William D. Hill, and John Q. Trojanowski. "β-Amyloid Peptide and Amyloid Precursor Proteins in Olfactory Mucosa of Patients with Alzheimer's Disease, Parkinson's Disease, and down Syndrome." Annals of Otology, Rhinology & Laryngology 104, no. 8 (August 1995): 655–61. http://dx.doi.org/10.1177/000348949510400812.
Ghiso, J., T. Wisniewski, R. Vidal, A. Rostagno, and B. Frangione. "Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease." Biochemical Journal 282, no. 2 (March 1, 1992): 517–22. http://dx.doi.org/10.1042/bj2820517.
van den Hurk, Wilhelmina H., Heidi J. J. Willems, Marjon Bloemen, and Gerard J. M. Martens. "Novel Frameshift Mutations near Short Simple Repeats." Journal of Biological Chemistry 276, no. 15 (January 3, 2001): 11496–98. http://dx.doi.org/10.1074/jbc.m011040200.
Yao, Yinan, Seong Su Kang, Yiyuan Xia, Zhi-Hao Wang, Xia Liu, Thorsten Muller, Yi E. Sun, and Keqiang Ye. "A delta-secretase-truncated APP fragment activates CEBPB, mediating Alzheimer’s disease pathologies." Brain 144, no. 6 (April 20, 2021): 1833–52. http://dx.doi.org/10.1093/brain/awab062.
Xie, Zhongcong, Yuanlin Dong, Uta Maeda, Paul Alfille, Deborah J. Culley, Gregory Crosby, and Rudolph E. Tanzi. "The Common Inhalation Anesthetic Isoflurane Induces Apoptosis and Increases Amyloid β Protein Levels." Anesthesiology 104, no. 5 (May 1, 2006): 988–94. http://dx.doi.org/10.1097/00000542-200605000-00015.
Huttunen, Henri J., Suzanne Y. Guénette, Camilla Peach, Christopher Greco, Weiming Xia, Doo Yeon Kim, Cory Barren, Rudolph E. Tanzi, and Dora M. Kovacs. "HtrA2 Regulates β-Amyloid Precursor Protein (APP) Metabolism through Endoplasmic Reticulum-associated Degradation." Journal of Biological Chemistry 282, no. 38 (August 6, 2007): 28285–95. http://dx.doi.org/10.1074/jbc.m702951200.
Grangeon, Lou, Kévin Cassinari, Stéphane Rousseau, Bernard Croisile, Maïté Formaglio, Olivier Moreaud, Jean Boutonnat, et al. "Early-Onset Cerebral Amyloid Angiopathy and Alzheimer Disease Related to an APP Locus Triplication." Neurology Genetics 7, no. 5 (September 8, 2021): e609. http://dx.doi.org/10.1212/nxg.0000000000000609.
Jowsey, Paul A., and Peter G. Blain. "Fe65 Ser228 is phosphorylated by ATM/ATR and inhibits Fe65–APP-mediated gene transcription." Biochemical Journal 465, no. 3 (January 22, 2015): 413–21. http://dx.doi.org/10.1042/bj20140656.
Nguyen, Khue Vu. "The human β-amyloid precursor protein: biomolecular and epigenetic aspects." Biomolecular Concepts 6, no. 1 (March 1, 2015): 11–32. http://dx.doi.org/10.1515/bmc-2014-0041.
Wang, Bo-Jeng, Guor Mour Her, Ming-Kuan Hu, Yun-Wen Chen, Ying-Tsen Tung, Pei-Yi Wu, Wen-Ming Hsu, et al. "ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer’s disease." Proceedings of the National Academy of Sciences 114, no. 15 (March 28, 2017): E3129—E3138. http://dx.doi.org/10.1073/pnas.1618804114.
Vaillant-Beuchot, Loan, Arnaud Mary, Raphaëlle Pardossi-Piquard, Alexandre Bourgeois, Inger Lauritzen, Fanny Eysert, Paula Fernanda Kinoshita, et al. "Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains." Acta Neuropathologica 141, no. 1 (October 20, 2020): 39–65. http://dx.doi.org/10.1007/s00401-020-02234-7.
Dorval, Véronique, Matthew J. Mazzella, Paul M. Mathews, Ronald T. Hay, and Paul E. Fraser. "Modulation of Aβ generation by small ubiquitin-like modifiers does not require conjugation to target proteins." Biochemical Journal 404, no. 2 (May 14, 2007): 309–16. http://dx.doi.org/10.1042/bj20061451.
Bussiere, Oulès, Mary, Vaillant-Beuchot, Martin, Manaa, Vallée, et al. "Upregulation of the Sarco-Endoplasmic Reticulum Calcium ATPase 1 Truncated Isoform Plays a Pathogenic Role in Alzheimer’s Disease." Cells 8, no. 12 (November 28, 2019): 1539. http://dx.doi.org/10.3390/cells8121539.
Augutis, Kristin, Markus Axelsson, Erik Portelius, Gunnar Brinkmalm, Ulf Andreasson, Mikael K. Gustavsson, Clas Malmeström, et al. "Cerebrospinal fluid biomarkers of β-amyloid metabolism in multiple sclerosis." Multiple Sclerosis Journal 19, no. 5 (October 15, 2012): 543–52. http://dx.doi.org/10.1177/1352458512460603.
K. Lakshmana, Madepalli, Subhojit Roy, Kaihong Mi, and David E. Kang. "Amyloidogenic Processing of APP in Lipid Rafts." Open Biology Journal 3, no. 1 (March 19, 2010): 21–31. http://dx.doi.org/10.2174/18741967010030100021.
Tan, Jing Zhi A., and Paul A. Gleeson. "The trans-Golgi network is a major site for α-secretase processing of amyloid precursor protein in primary neurons." Journal of Biological Chemistry 294, no. 5 (December 13, 2018): 1618–31. http://dx.doi.org/10.1074/jbc.ra118.005222.
Szögi, Titanilla, Ildikó Schuster, Emőke Borbély, Andrea Gyebrovszki, Zsolt Bozsó, János Gera, Róbert Rajkó, Miklós Sántha, Botond Penke, and Lívia Fülöp. "Effects of the Pentapeptide P33 on Memory and Synaptic Plasticity in APP/PS1 Transgenic Mice: A Novel Mechanism Presenting the Protein Fe65 as a Target." International Journal of Molecular Sciences 20, no. 12 (June 22, 2019): 3050. http://dx.doi.org/10.3390/ijms20123050.
Kuznetsov, I. A., and A. V. Kuznetsov. "Simulating the effect of formation of amyloid plaques on aggregation of tau protein." Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 474, no. 2220 (December 2018): 20180511. http://dx.doi.org/10.1098/rspa.2018.0511.
Masi, Mirco, Fabrizio Biundo, André Fiou, Marco Racchi, Alessia Pascale, and Erica Buoso. "The Labyrinthine Landscape of APP Processing: State of the Art and Possible Novel Soluble APP-Related Molecular Players in Traumatic Brain Injury and Neurodegeneration." International Journal of Molecular Sciences 24, no. 7 (April 2, 2023): 6639. http://dx.doi.org/10.3390/ijms24076639.
Netzer, William J., Karima Bettayeb, Subhash C. Sinha, Marc Flajolet, Paul Greengard, and Victor Bustos. "Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage." Proceedings of the National Academy of Sciences 114, no. 6 (January 23, 2017): 1389–94. http://dx.doi.org/10.1073/pnas.1620963114.
Hoe, Hyang-Sook, David Wessner, Uwe Beffert, Amanda G. Becker, Yasuji Matsuoka, and G. William Rebeck. "F-Spondin Interaction with the Apolipoprotein E Receptor ApoEr2 Affects Processing of Amyloid Precursor Protein." Molecular and Cellular Biology 25, no. 21 (November 1, 2005): 9259–68. http://dx.doi.org/10.1128/mcb.25.21.9259-9268.2005.
Schmitt, T. L. "Thyroid epithelial cells produce large amounts of the Alzheimer beta- amyloid precursor protein (APP) and generate potentially amyloidogenic APP fragments." Journal of Clinical Endocrinology & Metabolism 80, no. 12 (December 1, 1995): 3513–19. http://dx.doi.org/10.1210/jc.80.12.3513.
Schmitt, T. L., E. Steiner, P. Klingler, H. Lassmann, and B. Grubeck-Loebenstein. "Thyroid epithelial cells produce large amounts of the Alzheimer beta-amyloid precursor protein (APP) and generate potentially amyloidogenic APP fragments." Journal of Clinical Endocrinology & Metabolism 80, no. 12 (December 1995): 3513–19. http://dx.doi.org/10.1210/jcem.80.12.8530592.
Mori, Takashi, Naoki Koyama, Tatsuya Segawa, Masahiro Maeda, Nobuhiro Maruyama, Noriaki Kinoshita, Huayan Hou, Jun Tan, and Terrence Town. "Methylene Blue Modulates β-Secretase, Reverses Cerebral Amyloidosis, and Improves Cognition in Transgenic Mice." Journal of Biological Chemistry 289, no. 44 (August 25, 2014): 30303–17. http://dx.doi.org/10.1074/jbc.m114.568212.
Hefter, Dimitri, Susann Ludewig, Andreas Draguhn, and Martin Korte. "Amyloid, APP, and Electrical Activity of the Brain." Neuroscientist 26, no. 3 (November 29, 2019): 231–51. http://dx.doi.org/10.1177/1073858419882619.
BORCHARDT, Thilo, James CAMAKARIS, Roberto CAPPAI, Colin L. MASTERS, Konrad BEYREUTHER, and Gerd MULTHAUP. "Copper inhibits β-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion." Biochemical Journal 344, no. 2 (November 24, 1999): 461–67. http://dx.doi.org/10.1042/bj3440461.
Barron, A. M., M. Cake, G. Verdile, and R. N. Martins. "Ovariectomy and 17β-Estradiol Replacement Do Not Alter β-Amyloid Levels in Sheep Brain." Endocrinology 150, no. 7 (March 12, 2009): 3228–36. http://dx.doi.org/10.1210/en.2008-1252.
Paschou, Maria, Danai Liaropoulou, Vasileia Kalaitzaki, Spiros Efthimiopoulos, and Panagiota Papazafiri. "Knockdown of Amyloid Precursor Protein Increases Ion Channel Expression and Alters Ca2+ Signaling Pathways." International Journal of Molecular Sciences 24, no. 3 (January 24, 2023): 2302. http://dx.doi.org/10.3390/ijms24032302.
Li, Wei, Xiang Gao, Junle Ren, Ting An, and Yan Liu. "High Expression and Purification of Amino-Terminal Fragment of Human Amyloid Precursor Protein inPichia pastorisand Partial Analysis of Its Properties." BioMed Research International 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/836429.
Bergman, Anna, Hanna Laudon, Bengt Winblad, Johan Lundkvist, and Jan Näslund. "The Extreme C Terminus of Presenilin 1 Is Essential for γ-Secretase Complex Assembly and Activity." Journal of Biological Chemistry 279, no. 44 (August 20, 2004): 45564–72. http://dx.doi.org/10.1074/jbc.m407717200.