Journal articles on the topic 'Apc protein'
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Brugge, Jeroen, Guido Tans, Jan Rosing, and Elisabetta Castoldi. "Protein S levels modulate the activated protein C resistance phenotype induced by elevated prothrombin levels." Thrombosis and Haemostasis 95, no. 02 (2006): 236–42. http://dx.doi.org/10.1160/th05-08-0582.
Full textSen, Prosenjit, Sanghamitra Sahoo, Usha Pendurthi, and L. Vijaya Mohan Rao. "Zinc Binding to Protein C and Activated Protein C Modulates Their Interaction with Endothelial Cell Protein C Receptor." Blood 114, no. 22 (November 20, 2009): 331. http://dx.doi.org/10.1182/blood.v114.22.331.331.
Full textPreston, Roger JS, Shona Harmon, Fionnuala B. Ni Ainle, Jennifer A. Johnson, Moya Cunningham, O. Smith, Barry White, and James S. O’Donnell. "Dissociation of Activated Protein C Functions by Elimination of Protein S Cofactor Enhancement." Blood 112, no. 11 (November 16, 2008): 21. http://dx.doi.org/10.1182/blood.v112.11.21.21.
Full textMarx, Antje, Hans Weiler, Volker Liebe, Siegfried Lang, Jens Kaden, Wolfgang Zieger, Martin Borggrefe, Guenter Huhle, Karl Haase, and Martina Brueckmann. "Stabilization of monocyte chemoattractant protein-1-mRNA by activated protein C." Thrombosis and Haemostasis 89, no. 01 (2003): 149–60. http://dx.doi.org/10.1055/s-0037-1613554.
Full textMaurissen, Lisbeth F. A., M. Christella L. G. D. Thomassen, Gerry A. F. Nicolaes, Björn Dahlbäck, Guido Tans, Jan Rosing, and Tilman M. Hackeng. "Re-evaluation of the role of the protein S-C4b binding protein complex in activated protein C-catalyzed factor Va-inactivation." Blood 111, no. 6 (March 15, 2008): 3034–41. http://dx.doi.org/10.1182/blood-2007-06-089987.
Full textNishioka, Junji, Masaru Ido, Tatsuya Hayashi, and Koji Suzuki. "The Gla26 Residue of Protein C Is Required for the Binding of Protein C to Thrombomodulin and Endothelial Cell Protein C Receptor, but not to Protein S and Factor Va." Thrombosis and Haemostasis 75, no. 02 (1996): 275–82. http://dx.doi.org/10.1055/s-0038-1650260.
Full textPérez-Casal, Margarita, Colin Downey, Kenji Fukudome, Gernot Marx, and Cheng Hock Toh. "Activated protein C induces the release of microparticle-associated endothelial protein C receptor." Blood 105, no. 4 (February 15, 2005): 1515–22. http://dx.doi.org/10.1182/blood-2004-05-1896.
Full textPreston, Roger JS, Jennifer A. Johnson, Fionnuala Ni Ainle, Shona Harmon, Owen P. Smith, Barry White, and James S. O’Donnell. "Platelet Factor 4 Mediates Activated Protein C Resistance by Impairment of Protein S Cofactor Enhancement." Blood 112, no. 11 (November 16, 2008): 20. http://dx.doi.org/10.1182/blood.v112.11.20.20.
Full textde Fouw, N. J., Y. F. de Jong, F. Haverkate, and R. M. Bertina. "Activated Protein C Increases Fibrin Clot Lysis by Neutralization of Plasminogen Activator Inhibitor No Evidence for a Cofactor Role of Protein S." Thrombosis and Haemostasis 60, no. 02 (1988): 328–33. http://dx.doi.org/10.1055/s-0038-1647055.
Full textDeane, Rashid, Barbra LaRue, Abhay P. Sagare, Francis J. Castellino, Zhihui Zhong, and Berislav V. Zlokovic. "Endothelial Protein C Receptor-Assisted Transport of Activated Protein C across the Mouse Blood—Brain Barrier." Journal of Cerebral Blood Flow & Metabolism 29, no. 1 (October 8, 2008): 25–33. http://dx.doi.org/10.1038/jcbfm.2008.117.
Full textVan Walderveen, Maria Christina, Leslie R. Berry, and Anthony Chan. "Covalent Antithrombin-Heparin Complex Catalysis of Activated Protein C Inhibition by Protein C Inhibitor." Blood 114, no. 22 (November 20, 2009): 3167. http://dx.doi.org/10.1182/blood.v114.22.3167.3167.
Full textBrinkman, Herm Jan, Erica Sellink, Bas de Laat, and Koen Mertens. "Differential Anticoagulant Effects of Protein S on Vascular Cells and Platelets." Blood 112, no. 11 (November 16, 2008): 2026. http://dx.doi.org/10.1182/blood.v112.11.2026.2026.
Full textJörgensen, Pia-Marie, Eva Brundell, Maria Starborg, and Christer Höög. "A Subunit of the Anaphase-Promoting Complex Is a Centromere-Associated Protein in Mammalian Cells." Molecular and Cellular Biology 18, no. 1 (January 1, 1998): 468–76. http://dx.doi.org/10.1128/mcb.18.1.468.
Full textBolte, Melanie, Patrick Dieckhoff, Cindy Krause, Gerhard H. Braus, and Stefan Irniger. "Synergistic inhibition of APC/C by glucose and activated Ras proteins can be mediated by each of the Tpk1–3 proteins in Saccharomyces cerevisiae." Microbiology 149, no. 5 (May 1, 2003): 1205–16. http://dx.doi.org/10.1099/mic.0.26062-0.
Full textJoslyn, G., D. S. Richardson, R. White, and T. Alber. "Dimer formation by an N-terminal coiled coil in the APC protein." Proceedings of the National Academy of Sciences 90, no. 23 (December 1, 1993): 11109–13. http://dx.doi.org/10.1073/pnas.90.23.11109.
Full textWijnen, Merel van, Jeanette G. Stam, Cornells van't Veer, Joost C. M. Meijers, Pieter H. Reitsma, Rogier M. Bertina, and Bonno N. Bouma. "The Interaction of Protein S with the Phospholipid Surface Is Essential for the Activated Protein C-independent Activity of Protein S." Thrombosis and Haemostasis 76, no. 03 (1996): 397–403. http://dx.doi.org/10.1055/s-0038-1650590.
Full textPerez-Casal, Margarita, Kenji Fukudome, and Cheng Hock Toh. "A Novel Mechanism of Endothelial Protein C Receptor Release, in Microparticulate Form, by Activated Protein C." Blood 104, no. 11 (November 16, 2004): 1923. http://dx.doi.org/10.1182/blood.v104.11.1923.1923.
Full textHACKENG, Tilman M., Subramanian YEGNESWARAN, Arthur E. JOHNSON, and John H. GRIFFIN. "Conformational changes in activated protein C caused by binding of the first epidermal growth factor-like module of protein S." Biochemical Journal 349, no. 3 (July 25, 2000): 757–64. http://dx.doi.org/10.1042/bj3490757.
Full textvan der Meer, Felix J. M., Nico H. van Tilburg, Aat van Wijngaarden, Irma K. van der Linden, Ernest Briët, and Rogier M. Bertina. "A Second Plasma Inhibitor of Activated Protein C: α1-Antitrypsin." Thrombosis and Haemostasis 62, no. 02 (1989): 756–62. http://dx.doi.org/10.1055/s-0038-1646897.
Full textGruber, A., E. Mori, GJ del Zoppo, L. Waxman, and JH Griffin. "Alteration of fibrin network by activated protein C." Blood 83, no. 9 (May 1, 1994): 2541–48. http://dx.doi.org/10.1182/blood.v83.9.2541.2541.
Full textGruber, A., E. Mori, GJ del Zoppo, L. Waxman, and JH Griffin. "Alteration of fibrin network by activated protein C." Blood 83, no. 9 (May 1, 1994): 2541–48. http://dx.doi.org/10.1182/blood.v83.9.2541.bloodjournal8392541.
Full textMosnier, Laurent O., Jose A. Fernandez, Antonella Zampolli, Xia V. Yang, Zaverio M. Ruggeri, and John H. Griffin. "In Vivo Anti-Thrombotic Potency of Engineered Activated Protein C Variants." Blood 110, no. 11 (November 16, 2007): 2704. http://dx.doi.org/10.1182/blood.v110.11.2704.2704.
Full textYegneswaran, Subramanian, Phuong Nguyen, John Griffin, and Andrew Gale. "Prothrombin amino terminal region helps protect coagulation factor Va from proteolytic inactivation by activated protein C." Thrombosis and Haemostasis 101, no. 01 (2009): 55–61. http://dx.doi.org/10.1160/th08-07-0491.
Full textFeistritzer, Clemens, Laurent O. Mosnier, Enrico Di Cera, John H. Griffin, and Matthias Riewald. "Efficient Barrier Protective Signaling by Activated Protein C Is Mechanistically Linked to Protein C Activation on Endothelial Cells." Blood 106, no. 11 (November 16, 2005): 28. http://dx.doi.org/10.1182/blood.v106.11.28.28.
Full textFernandez, Jose A., Hiroshi Deguchi, Natalie M. Pecheniuk, Subramanian Yegneswaran, Carole L. Banka, and John H. Griffin. "Plasma High Density Lipoprotein and Anticoagulant Response to Activated Protein C (APC) and Protein S." Blood 118, no. 21 (November 18, 2011): 2249. http://dx.doi.org/10.1182/blood.v118.21.2249.2249.
Full textMosnier, Laurent O., Antonella Zampolli, Edward J. Kerschen, Reto A. Schuepbach, Yajnavalka Banerjee, José A. Fernández, Xia V. Yang, et al. "Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant." Blood 113, no. 23 (June 4, 2009): 5970–78. http://dx.doi.org/10.1182/blood-2008-10-183327.
Full textMosnier, Laurent O., Berislav V. Zlokovic, and John H. Griffin. "The cytoprotective protein C pathway." Blood 109, no. 8 (November 16, 2006): 3161–72. http://dx.doi.org/10.1182/blood-2006-09-003004.
Full textLi, Xian, Sara J. Bidarian, Martha Sim, Xiaohong Song, and Jeremy P. Wood. "Protein S Coordinates the Inhibition of Prothrombinase By Tfpiα and Activated Protein C." Blood 134, Supplement_1 (November 13, 2019): 2386. http://dx.doi.org/10.1182/blood-2019-130799.
Full textBarth, Angela I. M., Anne L. Pollack, Yoram Altschuler, Keith E. Mostov, and W. James Nelson. "NH2-terminal Deletion of β-Catenin Results in Stable Colocalization of Mutant β-Catenin with Adenomatous Polyposis Coli Protein and Altered MDCK Cell Adhesion." Journal of Cell Biology 136, no. 3 (February 10, 1997): 693–706. http://dx.doi.org/10.1083/jcb.136.3.693.
Full textGriffin, John H., Berislav V. Zlokovic, and Laurent O. Mosnier. "Activated protein C: biased for translation." Blood 125, no. 19 (May 7, 2015): 2898–907. http://dx.doi.org/10.1182/blood-2015-02-355974.
Full textOkajima, Kenji, Shin Koga, Megumi Kaji, Masayasu Inoue, Tomohiro Nakagaki, Akinobu Funatsu, Hiroaki Okabe, Kiyoshi Takatsuki, and Nobuo Aoki. "Effect of Protein C and Activated Protein C on Coagulation and Fibrinolysis in Normal Human Subjects." Thrombosis and Haemostasis 63, no. 01 (1990): 048–53. http://dx.doi.org/10.1055/s-0038-1645685.
Full textSun, Yong-Hui, Lei Shen, and Björn Dahlbäck. "Gla domain–mutated human protein C exhibiting enhanced anticoagulant activity and increased phospholipid binding." Blood 101, no. 6 (March 15, 2003): 2277–84. http://dx.doi.org/10.1182/blood-2002-06-1691.
Full textAhnström, Josefin, Helena M. Andersson, Kevin Canis, Eva Norstrøm, Yao Yu, Björn Dahlbäck, Maria Panico, Howard R. Morris, James T. B. Crawley, and David A. Lane. "Activated protein C cofactor function of protein S: a novel role for a γ-carboxyglutamic acid residue." Blood 117, no. 24 (June 16, 2011): 6685–93. http://dx.doi.org/10.1182/blood-2010-11-317099.
Full textLee, Yong-Seok, Sun-Lim Choi, Heejung Jun, Se-Jeong Yim, Jin-A. Lee, Hyoung F. Kim, Seung-Hee Lee, et al. "AU-rich element-binding protein negatively regulates CCAAT enhancer-binding protein mRNA stability during long-term synaptic plasticity in Aplysia." Proceedings of the National Academy of Sciences 109, no. 38 (September 4, 2012): 15520–25. http://dx.doi.org/10.1073/pnas.1116224109.
Full textVorlaufer, Elisabeth, and Jan-Michael Peters. "Regulation of the Cyclin B Degradation System by an Inhibitor of Mitotic Proteolysis." Molecular Biology of the Cell 9, no. 7 (July 1998): 1817–31. http://dx.doi.org/10.1091/mbc.9.7.1817.
Full textShea, Lei, Xuhua He, and Björn Dahlbäck. "Synergistic Cofactor Function of Factor V and Protein S to Activated Protein C in the Inactivation of the Factor Villa – Factor IXa Complex." Thrombosis and Haemostasis 78, no. 03 (1997): 1030–36. http://dx.doi.org/10.1055/s-0038-1657682.
Full textOstapenko, Denis, Janet L. Burton, Ruiwen Wang, and Mark J. Solomon. "Pseudosubstrate Inhibition of the Anaphase-Promoting Complex by Acm1: Regulation by Proteolysis and Cdc28 Phosphorylation." Molecular and Cellular Biology 28, no. 15 (June 2, 2008): 4653–64. http://dx.doi.org/10.1128/mcb.00055-08.
Full textKOYAMA, Takatoshi, and Shinsaku HIROSAWA. "Activated Protein C (APC) Resistance." Japanese Journal of Thrombosis and Hemostasis 5, no. 6 (1994): 442–46. http://dx.doi.org/10.2491/jjsth.5.442.
Full textKulkarni, Kiran, Ziguo Zhang, Leifu Chang, Jing Yang, Paula C. A. da Fonseca, and David Barford. "Building a pseudo-atomic model of the anaphase-promoting complex." Acta Crystallographica Section D Biological Crystallography 69, no. 11 (October 12, 2013): 2236–43. http://dx.doi.org/10.1107/s0907444913018593.
Full textD'Angelo, A., MS Lockhart, SV D'Angelo, and FB Jr Taylor. "Protein S is a cofactor for activated protein C neutralization of an inhibitor of plasminogen activation released from platelets." Blood 69, no. 1 (January 1, 1987): 231–37. http://dx.doi.org/10.1182/blood.v69.1.231.231.
Full textD'Angelo, A., MS Lockhart, SV D'Angelo, and FB Jr Taylor. "Protein S is a cofactor for activated protein C neutralization of an inhibitor of plasminogen activation released from platelets." Blood 69, no. 1 (January 1, 1987): 231–37. http://dx.doi.org/10.1182/blood.v69.1.231.bloodjournal691231.
Full textWang, Yang, Yoshiaki Azuma, David Moore, Neil Osheroff, and Kristi L. Neufeld. "Interaction between Tumor Suppressor Adenomatous Polyposis Coli and Topoisomerase IIα: Implication for the G2/M Transition." Molecular Biology of the Cell 19, no. 10 (October 2008): 4076–85. http://dx.doi.org/10.1091/mbc.e07-12-1296.
Full textBarford, David. "Structure, function and mechanism of the anaphase promoting complex (APC/C)." Quarterly Reviews of Biophysics 44, no. 2 (November 22, 2010): 153–90. http://dx.doi.org/10.1017/s0033583510000259.
Full textYasuda, Kyota, Huaye Zhang, David Loiselle, Timothy Haystead, Ian G. Macara, and Stavroula Mili. "The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules." Journal of Cell Biology 203, no. 5 (December 2, 2013): 737–46. http://dx.doi.org/10.1083/jcb.201306058.
Full textBerger, H. Jr, CG Kirstein, and CL Orthner. "Pharmacokinetics of activated protein C in guinea pigs." Blood 77, no. 10 (May 15, 1991): 2174–84. http://dx.doi.org/10.1182/blood.v77.10.2174.2174.
Full textBerger, H. Jr, CG Kirstein, and CL Orthner. "Pharmacokinetics of activated protein C in guinea pigs." Blood 77, no. 10 (May 15, 1991): 2174–84. http://dx.doi.org/10.1182/blood.v77.10.2174.bloodjournal77102174.
Full textQuinn, Louise M., Clive Drakeford, James S. O’Donnell, and Roger J. S. Preston. "Engineering activated protein C to maximize therapeutic efficacy." Biochemical Society Transactions 43, no. 4 (August 1, 2015): 691–95. http://dx.doi.org/10.1042/bst20140312.
Full textSpek, C. Arnold, and Valder Arruda. "The Role of Activated Protein C in Cancer." Blood 118, no. 21 (November 18, 2011): SCI—18—SCI—18. http://dx.doi.org/10.1182/blood.v118.21.sci-18.sci-18.
Full textBangalore, Neelesh, William N. Drohan, and Carolyn L. Orthner. "High Affinity Binding Sites for Activated Protein C and Protein C on Cultured Human Umbilical Vein Endothelial Cells." Thrombosis and Haemostasis 72, no. 03 (1994): 465–74. http://dx.doi.org/10.1055/s-0038-1648890.
Full textVáradi, K., J. Rosing, G. Tans, I. Pabinger, B. Keil, and H. P. Schwarz. "Factor V Enhances the Cofactor Function of Protein S in the APC-Mediated Inactivation of Factor VIII: Influence of the Factor VR506Q Mutation." Thrombosis and Haemostasis 76, no. 02 (1996): 208–14. http://dx.doi.org/10.1055/s-0038-1650556.
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