Academic literature on the topic 'APC model'

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Journal articles on the topic "APC model"

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Booth, JL, ES Duggan, VI Patel, et al. "ID: 106: ALVEOLAR ESCAPE BY BACILLUS ANTHRACIS SPORES DOES NOT REQUIRE A CARRIER CELL AND IS NOT ALTERED BY LETHAL TOXIN." Journal of Investigative Medicine 64, no. 4 (2016): 960.2–961. http://dx.doi.org/10.1136/jim-2016-000120.101.

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RationaleThe lung is the entry site for Bacillus anthracis in inhalation anthrax, the most deadly form of the disease. B. anthracis spores must escape from the alveolus, pass to the regional lymph nodes, germinate and enter the circulatory system as vegetative bacteria to cause systemic disease. Of the resident lung cells, three have been reported to take up B. anthracis spores: the antigen presenting cells (APC) alveolar macrophages and dendritic cells, and alveolar epithelial cells (AEC). Also, B. anthracis produces the exotoxins lethal factor and protective antigen (PA) which combine to for
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Kulkarni, Kiran, Ziguo Zhang, Leifu Chang, Jing Yang, Paula C. A. da Fonseca, and David Barford. "Building a pseudo-atomic model of the anaphase-promoting complex." Acta Crystallographica Section D Biological Crystallography 69, no. 11 (2013): 2236–43. http://dx.doi.org/10.1107/s0907444913018593.

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The anaphase-promoting complex (APC/C) is a large E3 ubiquitin ligase that regulates progression through specific stages of the cell cycle by coordinating the ubiquitin-dependent degradation of cell-cycle regulatory proteins. Depending on the species, the active form of the APC/C consists of 14–15 different proteins that assemble into a 20-subunit complex with a mass of approximately 1.3 MDa. A hybrid approach of single-particle electron microscopy and protein crystallography of individual APC/C subunits has been applied to generate pseudo-atomic models of various functional states of the comp
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Zeng, Biqing, Feng Zeng, Heng Yang, Wu Zhou, and Ruyang Xu. "Multi-task learning model for aspect term extraction and aspect polarity classification based on dual-labels." Journal of Intelligent & Fuzzy Systems 39, no. 3 (2020): 2763–74. http://dx.doi.org/10.3233/jifs-191047.

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Aspect-based sentiment analysis (ABSA) is a hot and significant task of natural language processing, which is composed of two subtasks, the aspect term extraction (ATE) and aspect polarity classification (APC). Previous researches generally studied two subtasks independently and designed neural network models for ATE and APC respectively. However, it integrates various manual features into the model, which will consume plenty of computing resources and labor. Moreover, the quality of the ATE results will affect the performance of APC. This paper proposes a multi-task learning model based on du
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Swietlicki, Elzbieta A., Shashi Bala, Jianyun Lu, et al. "Epimorphin deletion inhibits polyposis in the Apcmin/+ mouse model of colon carcinogenesis via decreased myofibroblast HGF secretion." American Journal of Physiology-Gastrointestinal and Liver Physiology 305, no. 8 (2013): G564—G572. http://dx.doi.org/10.1152/ajpgi.00486.2012.

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Interactions between the epithelium and surrounding mesenchyme/stroma play an important role in normal gut morphogenesis, the epithelial response to injury, and epithelial carcinogenesis. The tumor microenvironment, composed of stromal cells including myofibroblasts and immune cells, regulates tumor growth and the cancer stem cell niche. Deletion of epimorphin (Epim), a syntaxin family member expressed in myofibroblasts and macrophages, results in partial protection from colitis and from inflammation-induced colon cancer in mice. We sought to determine whether epimorphin deletion protects from
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Luo, Liying, and James S. Hodges. "Constraints in Random Effects Age-Period-Cohort Models." Sociological Methodology 50, no. 1 (2020): 276–317. http://dx.doi.org/10.1177/0081175020903348.

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Random effects (RE) models have been widely used to study the contextual effects of structures such as neighborhoods or schools. The RE approach has recently been applied to age-period-cohort (APC) models that are unidentified because the predictors are exactly linearly dependent. However, research has not fully explained how the RE specification identifies these otherwise unidentified APC models. We address this challenge by first making explicit that RE-APC models have greater—not less—rank deficiency than the traditional fixed-effects model, followed by two empirical examples. We then provi
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Arnljots, Björn, David Bergqvist, and Björn Dahlbäck. "Inhibition of Microarterial Thrombosis by Activated Protein C in a Rabbit Model." Thrombosis and Haemostasis 72, no. 03 (1994): 415–20. http://dx.doi.org/10.1055/s-0038-1648881.

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SummaryProtein C is the key component in a natural anticoagulant pathway. After its activation by the thrombin-thrombomodulin complex, it degrades the activated forms of coagulation cofactors VIII and V, which leads to downregulation of the coagulation process. Due to its specific anticoagulant activity, activated protein C (APC) is potentially interesting as an antithrombotic agent. The effect of bovine activated protein C on thrombus formation and haemostasis was investigated in a rabbit model of microarterial thrombosis. Segments of both central ear arteries were prepared and blood-flow int
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Zhang, Yongke, and Emma Lees. "Identification of an Overlapping Binding Domain on Cdc20 for Mad2 and Anaphase-Promoting Complex: Model for Spindle Checkpoint Regulation." Molecular and Cellular Biology 21, no. 15 (2001): 5190–99. http://dx.doi.org/10.1128/mcb.21.15.5190-5199.2001.

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ABSTRACT Activation of the anaphase-promoting complex (APC) is required for anaphase initiation and for exit from mitosis in mammalian cells. Cdc20, which specifically recognizes APC substrates involved in the metaphase-to-anaphase transition, plays a pivotal role in APC activation through direct interaction with the APC. The activation of the APC by Cdc20 is prevented by the interaction of Cdc20 with Mad2 when the spindle checkpoint is activated. Using deletion mutagenesis and peptide mapping, we have identified the sequences in Cdc20 that target it to Mad2 and the APC, respectively. These se
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Hoogendoorn, H., ME Nesheim, and AR Giles. "A qualitative and quantitative analysis of the activation and inactivation of protein C in vivo in a primate model." Blood 75, no. 11 (1990): 2164–71. http://dx.doi.org/10.1182/blood.v75.11.2164.2164.

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Abstract A model of Protein C (PC) activation in vivo was used to investigate the complexing of activated PC (APC) with its plasma inhibitors, PC inhibitor (PCI) and alpha 1-antitrypsin (alpha 1AT). Chimpanzees were infused with a bolus of activated factor X (F.Xa) together with vesicles of phosphatidylcholine and phosphatidylserine (PCPS). Pre- and post-infusion plasma samples were analyzed using enzyme linked immunosorbent based assays (ELISA) for PC and APC complexes, and immunoblotting of PC from nondenaturing polyacrylamide gel electrophoresis. Within 2 minutes of infusion, a 60% decrease
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Hoogendoorn, H., ME Nesheim, and AR Giles. "A qualitative and quantitative analysis of the activation and inactivation of protein C in vivo in a primate model." Blood 75, no. 11 (1990): 2164–71. http://dx.doi.org/10.1182/blood.v75.11.2164.bloodjournal75112164.

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A model of Protein C (PC) activation in vivo was used to investigate the complexing of activated PC (APC) with its plasma inhibitors, PC inhibitor (PCI) and alpha 1-antitrypsin (alpha 1AT). Chimpanzees were infused with a bolus of activated factor X (F.Xa) together with vesicles of phosphatidylcholine and phosphatidylserine (PCPS). Pre- and post-infusion plasma samples were analyzed using enzyme linked immunosorbent based assays (ELISA) for PC and APC complexes, and immunoblotting of PC from nondenaturing polyacrylamide gel electrophoresis. Within 2 minutes of infusion, a 60% decrease in nonac
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Fosse, Ethan, and Christopher Winship. "Analyzing Age-Period-Cohort Data: A Review and Critique." Annual Review of Sociology 45, no. 1 (2019): 467–92. http://dx.doi.org/10.1146/annurev-soc-073018-022616.

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Age-period-cohort (APC) analysis has a long, controversial history in sociology and related fields. Despite the existence of hundreds, if not thousands, of articles and dozens of books, there is little agreement on how to adequately analyze APC data. This article begins with a brief overview of APC analysis, discussing how one can interpret APC effects in a causal way. Next, we review methods that obtain point identification of APC effects, such as the equality constraints model, Moore-Penrose estimators, and multilevel models. We then outline techniques that entail point identification using
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Dissertations / Theses on the topic "APC model"

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Mtotywa, Matolwandile Mzuvukile. "Productivity measurement and its relationship to quality in a South African Minting Company." Thesis, University of South Africa, 2007. http://hdl.handle.net/10500/51.

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The aim of this study was to investigate a productivity measurement at the South African Minting Company and evaluate the relationship between productivity and quality. Special emphasis was given to profit-linked total factor model as the tool for measurement. This was encouraged by their ability to separate productivity, profitability and price recovery. Three models were selected and evaluated. These models American Productivity Center (APC) Model, “Profitability = productivity + price recovery” (PPP) model and multi-factor productivity measurement model (MFPMM). APC model was select
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Elahi, Eiram. "QTL mapping of Apc modifiers in an ApcMin/+ mouse model of spontaneous and irradiation-induced intestinal adenomas." Thesis, Queen Mary, University of London, 2013. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8717.

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BACKGROUND: Radiation exposure to the abdominal region causes intestinal toxicity and is also capable of inducing colorectal cancers (CRC). Genotype-phenotype studies provide some evidence explaining the variation in familial adenomatous polyposis (FAP) patients caused by modifiers of adenomatous polyposis coli (APC). This study aims to extend our understanding of irradiation-induced modifiers of ApcMin/+ mice and CRC. METHODS: By using a pre-existing backcross between recombinant inbred line of ApcMin/+ mice to the irradiation sensitive inbred BALB/c mouse, we obtained panels of 2Gy-irradiate
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Wong, Wing Yan. "Proteomics analysis of anti-cancer effects of gynostemma pentaphyllum saponins in Apc min/+ colorectal cancer mouse model." HKBU Institutional Repository, 2012. https://repository.hkbu.edu.hk/etd_ra/1421.

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Duh, Camilla, and Carsten Daub. "A Model to Enhance the Effectiveness of Machining Centers with Automatic Multi-Pallet Changers: a Case Study." Thesis, Växjö University, School of Technology and Design, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-938.

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<p>The purpose of this thesis is to develop a model to enhance the effectiveness of machining centers with multi-pallet automatic pallet changers (APCs). From critical literature review no existing theories within this field were found. The multi-pallet APC allows multi-setups and a more flexible sequencing of jobs. The model together with the developed heuristic scheduling algorithm with the objective to minimize the total weighted tardiness can be used to plan in n jobs on m pallets in a shop-floor. The right maintenance policy ensures a high availability, which together with the program gua
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Jordan, Sumanas W. "A mathematical model of tissue factor-induced blood coagulation: discrete sites of initiation and regulation under conditions of flow." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/33907.

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A mathematical model of blood coagulation under defined flow conditions, initiated and modulated by spatially discrete regions of surface bound tissue factor (TF) and thrombomodulin (TM), respectively, is presented. The model incorporates fluid phase and surface-associated reactions of the extrinsic, intrinsic, and common pathways, as well as three inhibitory pathways. The spatially heterogeneous model is formulated by finite element method, and an effective prothrombotic zone, which quantifies the spatial propagation of thrombin generation is defined. Characteristic features of coagulation
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Orhun, Eda, and Blanka Grubjesic. "Value at Risk (VaR) Method : An Application for Swedish National Pension Funds (AP1, AP2, AP3) by Using Parametric Model." Thesis, University of Skövde, School of Technology and Society, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-129.

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<p>Value at Risk (VaR) approach has been extensively used by investment and commercial banks since its development by JP Morgan in 1990s. As time passes, it has become interesting to investigate whether VaR could be used also by other financial intermediaries like pension funds and insurance companies. The aim of this paper is to outline Value at Risk (VaR) methodology by giving more emphasis on parametric approach which is used for empirical section and to investigate the applicability and usefulness of VaR in pension funds. After providing theoretical framework for VaR approach, the paper co
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Al-Mashat, Alex. "Comparison of Multiple Models for Diabetes Using Model Averaging." Thesis, Uppsala universitet, Institutionen för farmaci, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-448168.

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Pharmacometrics is widely used in drug development. Models are developed to describe pharmacological measurements with data gathered from a clinical trial. The information can then be applied to, for instance, safely establish dose-response relationships of a substance. Glycated hemoglobin (HbA1c) is a common biomarker used by models within antihyperglycemic drug development, as it reflects the average plasma glucose level over the previous 8-12 weeks. There are five different nonlinear mixed-effects models that describes HbA1c-formation. They use different biomarkers such as mean plasma gluco
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Schenk, Judith A. "Criteria for Evaluating Model Deficiency for Groundwater Models and the Effects of Eliminating Deficient Models on Multi Model Analysis Using AICc, KIC, AIC, and BIC." Thesis, Colorado School of Mines, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10266759.

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<p> Multi-model analysis (MMA) considers multiple model interpretations of a system. MMA provides a more realistic assessment of uncertainty associated with model predictions because both uncertainty of individual models and uncertainty associated with different model structures are considered. Models are evaluated for the strength of evidence that they represent an unknown system using different Information Criteria (IC) equations. IC equations are designed to assess the likelihood that a model in a set of models represents the true but unknown system. IC equations do not include a component
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Kooshkghazi, Mahshid Deghan. "Chemoprevention of intestinal cancer : dietary and pharmaceutical interventions in mutant Apc mouse models." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388729.

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Correia, Gonçalo Emanuel Coimbra Lamas Pereira. "Gestão de stocks numa unidade de ressonância magnética." Master's thesis, Instituto Superior de Economia e Gestão, 2011. http://hdl.handle.net/10400.5/3476.

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Mestrado em Gestão e Estratégia Industrial<br>Nos últimos anos a gestão de stocks tornou-se numa ferramenta fundamental para os prestadores de cuidados de saúde, que procuram a racionalização de custos com medicamentos e materical clínico, através de uma maior eficiência operacional. Este trabalho visa o estudo da relação entre classificações e modelos de gestão de stocks, e ilustra a sua aplicação em prestadores de cuidados de saúde, na área da imagiologia, em particular numa unidade de ressonância magnética. Neste estudo optou-se por uma classificação de stocks baseada em métodos analíticos,
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Books on the topic "APC model"

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Elina, Ol'ga. The concept of priority development of the export of products of agro-industrial complex of Russia until 2024. INFRA-M Academic Publishing LLC., 2020. http://dx.doi.org/10.12737/1023826.

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The book describes the development of resulting research opportunities and prospects of promoting the products of agro-industrial complex (AIC) of Russia in the international markets. The authors ' study showed that Russia continues to increase its place in world trade of agricultural products. &#x0D; Presents the author's concept of increasing exports of agricultural products to Russia to $ 45 billion by 2024, identified strategic options, and proposed development model of export agriculture, the expedience, methods and instruments of realization of measures of state support of export of agri
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Ali, H. M. J. Static model of an A.C. circuit breaker. UMIST, 1994.

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Ciok, Zbigniew. Modele matematyczne łuku łączeniowego. Państwowe Wydawn. Nauk., 1987.

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Sliwinski, B. A model of U.S. Army Materiel Command (AMC) energy consumption. US Army Corps of Engineers, Construction Engineering Research Laboratory, 1986.

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Pusan, Korea) APCN Meeting 2004 (2004. Fourth APCN Working Group Meeting, Third APCN Steering Committee Meeting. Korea Meteorological Administration, 2004.

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Schuweiler, Alan R. Greenberg's guide to American Flyer wide gauge. Greenberg Pub. Co., 1989.

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Fazenbaker, Jack. Greenberg's price guide and inventory checklist to American Flyer, S gauge. Greenberg Pub. Co., 1986.

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Faust, Jeff. Greenberg's American flyer track plans and operating instructions. Greenberg Pub. Co., 1989.

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Svehar, Gary T. American Flyer: S gauge parts lists and exploded diagrams, 1979-1991. Greenberg Pub. Co., 1991.

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C, Patterson James. Greenberg's guide to American Flyer S gauge. 3rd ed. Greenberg Pub. Co., 1988.

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Book chapters on the topic "APC model"

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Taketo, M. M. "Apc Gene Knockout Mice as a Model for Familial Adenomatous Polyposis." In Animal Models of Cancer Predisposition Syndromes. KARGER, 1999. http://dx.doi.org/10.1159/000062007.

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Iqbal, Anjum, and Mohd Aizani Maarof. "Towards Danger Theory Based Artificial APC Model: Novel Metaphor for Danger Susceptible Data Codons." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-540-30220-9_13.

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Liu, Xinping, Xiwen Xue, and Mingwen Zheng. "The RBFNN ’s Application in Nonlinear System Model Based on Improved APC-III Algorithm." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13498-2_74.

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Pugh, Clifford A. "Sediment Transport Scaling for Physical Models." In Sedimentation Engineering. American Society of Civil Engineers, 2008. http://dx.doi.org/10.1061/9780784408148.apc.

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Good, Kenneth. "Elitism’s Place in the ANC." In The Liberal Model and Africa. Palgrave Macmillan UK, 2002. http://dx.doi.org/10.1057/9780230001138_4.

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Tschudi, Finn, and David Winter. "The ABC Model Revisited." In Personal Construct Methodology. John Wiley & Sons, Ltd, 2011. http://dx.doi.org/10.1002/9781119953616.ch4.

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Bucanek, James. "Model Citizen." In Learn iOS App Development. Apress, 2013. http://dx.doi.org/10.1007/978-1-4302-5063-0_8.

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Bucanek, James. "Model Citizen." In Learn iOS 8 App Development. Apress, 2014. http://dx.doi.org/10.1007/978-1-4842-0208-1_8.

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Doursat, Christophe, and Joël Priolon. "The Cox, Ross and Rubinstein model." In Financial Markets for Commodities. John Wiley & Sons, Inc., 2019. http://dx.doi.org/10.1002/9781119579274.app.

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Groce, Alex, Doron Peled, and Mihalis Yannakakis. "AMC: An Adaptive Model Checker." In Computer Aided Verification. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/3-540-45657-0_44.

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Conference papers on the topic "APC model"

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Morisawa, Toshihiro, Hiromichi Kobayashi, and Yukio Takeda. "Non-Linear Process Model for CMP-APC." In 2011 International Conference on Management and Service Science (MASS 2011). IEEE, 2011. http://dx.doi.org/10.1109/icmss.2011.5999338.

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Xu, Jingqi, Haode Liu, and Jing Teng. "Optimization Model for Bus Timetable Based on APC." In Eighth International Conference of Chinese Logistics and Transportation Professionals (ICCLTP). American Society of Civil Engineers, 2009. http://dx.doi.org/10.1061/40996(330)659.

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Shaowu Cheng, Baoyi Liu, and Botao Zhai. "Bus arrival time prediction model based on APC data." In 6th Advanced Forum on Transportation of China (AFTC 2010). IET, 2010. http://dx.doi.org/10.1049/cp.2010.1123.

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Baloch, Mohammad Adnan, I. Ismail, Noor Hazrin Hany binti Mohamad Hanif, and T. M. Baloch. "ANFIS identification model of an Advanced Process Control (APC) pilot plant." In Advanced Systems (ICIAS 2010). IEEE, 2010. http://dx.doi.org/10.1109/icias.2010.5716224.

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Mao, Ziqiang J., and Issi Geier. "Model-based fault detection and metrology error rejection in registration APC system." In Microlithography 2004, edited by Kenneth W. Tobin, Jr. SPIE, 2004. http://dx.doi.org/10.1117/12.536810.

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Chen, Wei-Ya, and Zhi-Ya Chen. "A Simulation Model for Transit Service Unreliability Prevention Based on AVL-APC Data." In 2009 International Conference on Measuring Technology and Mechatronics Automation. IEEE, 2009. http://dx.doi.org/10.1109/icmtma.2009.77.

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Zheng, Mingwen, and YanPing Zhang. "An Improved APC-III Algorithm's RBFNN and its Application in the Nonlinear System Model." In 2010 International Conference on Intelligent Computation Technology and Automation (ICICTA). IEEE, 2010. http://dx.doi.org/10.1109/icicta.2010.202.

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Tumlinson, Alexandre R., Jennifer K. Barton, James McNally, et al. "Imaging APC/Min(+/−) colon cancer model mice with ultrahigh resolution endoscopic FD-OCT at 800nm." In Frontiers in Optics. OSA, 2005. http://dx.doi.org/10.1364/fio.2005.fmc1.

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Samaras, Patroklos, Anestis Fachantidis, Grigorios Tsoumakas, and Ioannis Vlahavas. "A prediction model of passenger demand using AVL and APC data from a bus fleet." In PCI '15: 19th Panhellenic Conference on Informatics. ACM, 2015. http://dx.doi.org/10.1145/2801948.2801984.

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Wojtal, Daria, Roopali Chaudhary, Kyster K. Nanan, Simona Morone, and Juliet M. Daniel. "Abstract 1302: Effect of intestinal-specific Kaiso overexpression on the APC MIN/+ mouse colon cancer model." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1302.

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Reports on the topic "APC model"

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Chu, Xuehao. Validating T-BEST Models with 100% APC Counts. University of South Florida, 2007. http://dx.doi.org/10.5038/cutr-nctr-rr-2005-02.

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Berzins, Valdis. Acoustic Simulation API Requirements Model. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada442126.

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Gormley, M., and S. O'Day. An Updated AP2 Beamline TURTLE Model. Office of Scientific and Technical Information (OSTI), 1991. http://dx.doi.org/10.2172/983972.

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Watanabe, R., and R. Han. Upgrading of Agc Sediment Transport Model. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1987. http://dx.doi.org/10.4095/126108.

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Roth, Christopher. AE9/AP9/SPM Radiation Environment Model: User's Guide. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada603883.

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Whelan, Paul. AE9/AP9/SPM Model Application Programming Interface, Version 1.00.000. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada603361.

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Hamm, L. L. APT Blanket System Model Based on Initial Conceptual Design - Integrated 1D TRAC System Model. Office of Scientific and Technical Information (OSTI), 1998. http://dx.doi.org/10.2172/4915.

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Bennett, M. V., and J. M. Bennett. Aircraft Engine/APU Fire Extinguishing System Design Model (HFC-125). Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/ada373212.

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Hamm, L. L. APT Blanket Detailed Bin Model Based on Initial Plate-Type Design -3D FLOWTRAN-TF Model. Office of Scientific and Technical Information (OSTI), 1998. http://dx.doi.org/10.2172/4913.

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Krakowski, R. A. APT cost scaling: Preliminary indications from a Parametric Costing Model (PCM). Office of Scientific and Technical Information (OSTI), 1995. http://dx.doi.org/10.2172/39121.

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