Relevant bibliographies by topics / Aorta

Academic literature on the topic 'Aorta'

Author: Grafiati
Published: 4 June 2021
Last updated: 29 July 2024

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Journal articles on the topic "Aorta"

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Popov, V. V., and A. A. Bolshak. "Procedure of complex braided wrapping of ascending aorta in her poststenotic dilation while doing correction of aortal stenosis." Klinicheskaia khirurgiia 87, no. 9-10 (October 29, 2020): 18–21. http://dx.doi.org/10.26779/2522-1396.2020.9-10.18.

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Objective. To study clinical possibilities of original procedure of the ascending aorta braid-like bandage for her poststenotic dilation while performance of the aortal stenosis surgical correction. Materials and methods. To the main Group 196 patients were included those, who were operated on for prevailing aortal stenosis, conjoined with poststenotic dilation of ascending aorta. In accordance to the echocardiographic investigation data the ascending aorta diameter preoperatively have constituted (47.7 ± 1.7) mm. In all the patients the aortal valve prosthesis was performed together with complex braided wrapping of ascending aorta. Into the control group 121 patients were included, in whom Bentall intervention was accomplished with vascular prosthesis of ascending aorta. Results. Hospital lethality in the main group have constituted 0.5%. Diameter of ascending aorta in the moment of hospital discharge have constituted (39.1 ± 1.5) mm, and in late follow-up period - (40.3 ± 1.1) mm. Conclusion. Basing on clinical experience gained, it is expedient to recommend the original procedure of braided wrapping of ascending aorta in presence of her poststenotic dilation while performing surgical correction of prevailing aortal stenosis.
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Neves, Ana Augusta Gayoso, Alexandre Gayoso Neves Maia de Oliveira, Roberto Teodoro Beck, Ricardo Virginio dos Santos, Francisco Carlos Padilha Moreira, and Alexandre Campos Moraes Amato. "Tratamento endovascular de pseudoaneurisma de aorta torácica com fístula aorto-brônquica em pós-operatório tardio de cirurgia de correção de coarctação de aorta." Jornal Vascular Brasileiro 10, no. 1 (March 2011): 64–67. http://dx.doi.org/10.1590/s1677-54492011000100012.

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Fístula aorto-brônquica é uma conexão entre a aorta e o brônquio, e mesmo quando imediatamente reconhecida e tratada possui alto risco de letalidade. Pode se desenvolver após cirurgias de aorta, e é geralmente uma consequência de pseudoaneurisma. A hemoptise, massiva ou intermitente, é o principal sintoma apresentado. O tratamento convencional da fístula aorto-brônquica é a cirurgia aberta de aorta torácica, com reconstrução traqueobrônquica. Recentemente, o reparo endovascular tem sido proposto como uma alternativa. Os autores apresentam um relato de tratamento endovascular, realizado com êxito, de pseudoaneurisma de aorta torácica com fístula aorto-brônquica 22 anos após cirurgia para correção de coarctação aórtica.
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Bennett, Damien, Diane Stewart, Deirdre Kearns, Adrian Mairs, and Peter Ellis. "Non-visualized aorta in abdominal aortic aneurysm screening: Screening outcomes and the influence of subject and programme characteristics." Journal of Medical Screening 24, no. 4 (January 11, 2017): 214–19. http://dx.doi.org/10.1177/0969141316680833.

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Objectives To compare abdominal aortic aneurysm screening outcomes of men with non-visualized aorta at original scan with subsequent scans and to determine predictors of non-visualized aorta. Methods In the Northern Ireland Abdominal Aortic Aneurysm screening programme, outcomes (discharge, annual surveillance, three-monthly surveillance, or vascular referral) and patient and programme characteristics (age, deprivation quintile, family history, technician experience, and screening location) for men with non-visualized aorta were investigated at original scan, and first and second rescans. Results Non-visualized aorta proportions were 2.9, 11.4, and 4.7% at original, first, and second rescan, respectively. There were no differences in screening outcomes between scanning stages (98.4, 97.6, and 97.4% <3 cm). There were 42 men (0.13%) with aortas ≥5.5 cm at original scan, but none at first and second rescan. A significantly greater proportion with non-visualized aorta were from more deprived (5.0%) than less deprived areas (1.7%). Deprivation quintile and staff role were significant independent non-visualized aorta predictors at original scan, and staff role at first rescan. Men from less deprived areas were three times as likely to have aortas visualized than those from more deprived areas (OR = 3.0, CI = 2.4–3.8) at original scan. A man scanned by screening technician compared with lead sonographer was 51% less likely to have aorta visualized at original scan and 94% less likely at first rescan. Conclusions The risk of abdominal aortic aneurysm in men with non-visualized aorta on first or subsequent rescans is no more than for those with visualized aorta on original scanning. Men from deprived areas are much more likely to have non-visualized aorta at original scan.
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Pahuja, Kavita, and Amardeep Bissa. "Segmental Representation of Intimal Thickness in Ascending Aorta as Early Clinical Marker of Aging." International Journal of Anatomy and Research 9, no. 2.1 (April 15, 2021): 7955–59. http://dx.doi.org/10.16965/ijar.2021.116.

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Background: Intimal thickness is the innermost layer of aorta; play a vital role in development of atherosclerotic changes. It may vary in the different parts of the aorta and may increase with age. Methods: 120 aortas of adult human forensic bodies were taken. Histological slides were formed and the thickness of different segments of aorta were measured microscopically. Data were statically analyzed using ANOVA, p test methods. Results and Discussion: There is no significant difference of Intimal thickness in different segments of ascending aorta though it significantly increase with age may be due to accumulation of medial SMCs into intima. Results agree with previous workers. Conclusion: No significant difference between different segments of ascending aorta and it increase with age showing the aging aorta and early sign of atherosclerotic changes. KEY WORDS: Aging, Intimal thickness, Age Groups, Smooth Muscle Cells, Medial thickness.
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Helin, Pekka, C. Garbarsch, G. Helin, and I. Lorenzen. "Vascular Injury Compared to Ageing of Normal Rabbit Aorta." Journal of Vascular Research 22, no. 2 (1985): 94–104. http://dx.doi.org/10.1159/000158588.

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Male albino rabbits of the Danish country strain, 5 months of age, were divided into two groups. One group of animals was killed 180 days after a single mechanical dilatation injury of the thoracic aorta. A second group of untreated controls was killed at ages of 150, 165, 180, 210, 330, and 450 days. Glycosaminoglycans, uptake of <sup>35</sup>S-sulphate, collagen, uptake of <sup>125</sup>I-albumin, and vascular histochemistry and morphology were analyzed in the thoracic aorta. In the injured aortae the dry weight and the total amounts of hexosamine, hyaluronic acid, chondroitin-4,6-sulphate, dermatan sulphate, heparan sulphate, and hydroxyprohne were increased. The concentration of hyaluronic acid decreased, whereas the concentration of dermatan sulphate increased. The concentrations of chondroitin-4,6-sulphate and heparan sulphate were unchanged. The total uptake of <sup>35</sup>S-sulphate into the sulphated proteoglycans as well as the uptake of <sup>125</sup>I-albumin were increased. The light microscopical examination showed thickening of the intima, medial changes with fibrosis, accumulations of proteoglycans, calcifications, formation of cartilage, and ossified tissue with haematopoiesis. In the uninjured thoracic aorta the only significant change during ageing was an increase in the total amount of hyaluronic acid and a decrease of the <sup>35</sup>S-sulphate incorporation into the chondroitin-4,6-sulphate in the aorta. No morphological or histochemical alterations were observed during ageing. Spontaneous lesions were observed in 2 out of 55 aortas. It may be concluded that injury and ageing are reflected quite differently in the thoracic aorta of the rabbits. The observations may be of relevance to the interpretation of the alterations in human arterial diseases involving processes of injury and repair as well as ageing.
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Harun, Andi L. A., Luthfi Attamimi, Nikmatia Latief, and Sri Asriyani. "Fistula Aorta - Atrium Kanan." Jurnal Biomedik:JBM 13, no. 3 (December 31, 2021): 352. http://dx.doi.org/10.35790/jbm.v13i3.33805.

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Abstract: Aortic - right atrial fistula is a channel of blood vessels originating from one of the valsalva sinuses and ending in the superior vena cava or right atrium. This fistula is an abnormal vascular connection that causes blood flow from the high-resistance aortic circuit to the low-resistance right atrium. We report a case of a 34-year-old male patient diagnosed with aortic - right atrial fistula with clinical manifestations of spasms since 1 month. The incidence of aortic - right atrial fistula is most common between the ages of 9 and 45 years. The cause of this condition appears to be an inherited deficiency / weakness of the elastic lamina in the aortic medium. Right aorto-atrial fistula has varied clinical manifestations such as acute pulmonary edema, chronic heart failure and can also be found incidentally. Cardiac MSCT with contrast shows the results of the aorta to right atrial fistula. This patient was treated with furosemide and aspilet treatment.Key words: Aortic - right atrial fistula, MSCT cardiac. Abstrak: Fistula aorta - atrium kanan adalah celah atau saluran pembuluh darah yang berasal dari salah satu sinus valsava dan berakhir di vena cava superior atau atrium kanan. Fistula ini merupakan koneksi vaskular abnormal yang menyebabkan aliran darah dari sirkuit aorta dengan resistensi tinggi ke atrium kanan dengan resistansi rendah. Kami melaporkan kasus pasien laki-laki berusia 34 tahun dengan diagnosis fistula aorta - atrium kanan dengan manifestasi klinis sesak sejak 1 bulan. Insiden fistula aorta - atrium kanan tersering pada usia antara 9 – 45 tahun. Penyebab kondisi ini tampaknya merupakan defisiensi / kelemahan bawaan lamina elastis di media aorta. Fistula aorto-atrium kanan memiliki manifestasi klinis bervariasi seperti edema paru akut, gagal jantung kronis dan dapat pula ditemukan secara insidental. Pada pemeriksaan MSCT cardiac dengan kontras mendapatkan hasil gambaran aorta to right atrial fistula. Pasien ini ditatalaksana dengan diberikan pengobatan furosemide dan aspilet.Kata kunci: Fistula aorta - atrium kanan, MSCT cardiac.
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Rhode, E. A., R. Elsner, T. M. Peterson, K. B. Campbell, and W. Spangler. "Pressure-volume characteristics of aortas of harbor and Weddell seals." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 251, no. 1 (July 1, 1986): R174—R180. http://dx.doi.org/10.1152/ajpregu.1986.251.1.r174.

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The mechanical properties of the radially enlarged proximal segment of the aorta of diving marine mammals was studied on 15 excised aortas of harbor seals and five aortas of Weddell seals. This was done by recording static pressure-volume relationships for the whole thoracic aorta, the aortic bulb, and the descending thoracic aorta and passive length-tension measurements of aortic strips. Aortic bulb volume distensibility was found to be much greater than that of the descending thoracic aorta or of an equivalent aortic segment of terrestrial mammals. The consequences were that the total potential energy and volume that may be stored within the aortic bulb is very large, with a capacity for storage of the stroke work of more than two normal heart beats and a volume of more than three times normal stroke volume. The aortic bulb has an average radius and wall thickness twice that of the descending aorta, but at any level of distension the wall stress (g/cm2) is the same throughout. The static mechanical properties of aortic strips from the bulb and descending thoracic aortas were not markedly different, so that the differences in the pressure-volume relationships are explained by differences in geometry of the two sections. The expanded aortic bulb functions through energy and volume storage actions and through uncoupling actions to maintain arterial pressures and stroke volume at near predive levels during a dive.
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Tinker, D., J. Geller, N. Romero, C. E. Cross, and R. B. Rucker. "Tropoelastin production and tropoelastin messenger RNA activity. Relationship to copper and elastin cross-linking in chick aorta." Biochemical Journal 237, no. 1 (July 1, 1986): 17–23. http://dx.doi.org/10.1042/bj2370017.

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The elastin content of the chick thoracic aorta increases 2--3-fold during the first 3 weeks post-hatching. The deposition of elastin requires the covalent cross-linking of tropoelastin by means of lysine-derived cross-links. This process is sensitive to dietary copper intake, since copper serves as cofactor for lysyl oxidase, the enzyme that catalyses the oxidative deamination of the lysine residues involved in cross-link formation. Disruption of cross-linking alters tissue concentrations of both elastin and tropoelastin and results in a net decrease in aortic elastin content. Autoregulation of tropoelastin synthesis by changes in the pool sizes of elastin or tropoelastin has been suggested as a possible mechanism for the diminished aortic elastin content. Consequently, dietary copper deficiency was induced to study the effect of impaired elastin cross-link formation on tropoelastin synthesis. Elastin in aortae from copper-deficient chicks was only two-thirds to one-half the amount measured in copper-supplemented chicks, whereas copper-deficient concentrations of tropoelastin in aorta were at least 5-fold higher than normal. In spite of these changes, however, increased amounts of tropoelastin, copper deficiency and decreased amounts of elastin did not influence the amounts of functional elastin mRNA in aorta. Likewise, the production of tropoelastin in aorta explants was the same whether the explants were taken from copper-sufficient or -deficient birds. The lower accumulation of elastin in aorta from copper-deficient chicks appeared to be due to extracellular proteolysis, rather than to a decrease in the rate of synthesis. Electrophoresis of aorta extracts, followed by immunological detection of tropoelastin-derived products, indicated degradation products in aortae from copper-deficient birds. In extracts of aortae from copper-sufficient chicks, tropoelastin was not degraded and appeared to be incorporated into elastin without further proteolytic processing.
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Khan, Aasim, and Thodur Vasudevan. "Hybrid technique for the management of thoracoabdominal aortic thrombosis and symptomatic Trans-Atlantic Inter-Society Consensus “C” aorto-iliac disease." Vascular 26, no. 3 (October 12, 2017): 331–34. http://dx.doi.org/10.1177/1708538117718645.

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Objective Thrombotic disease of the thoracic and abdominal aorta co-existing with aorto-iliac disease is a rare clinical association, which poses a great therapeutic challenge and adds to the complexity of the open surgical repair. Method We describe a case of 53-year-old woman with symptomatic thrombus in the thoracic and abdominal aorta down to the aortic bifurcation, which was successfully treated by Thoracic EndoVascular Aortic Repair via the left subclavian artery, open thrombectomy and aorto-iliac bypass. Result Completion angiogram performed through the axillary cannula showed good flow in the aorta, visceral vessels and iliac arteries. Conclusion This hybrid technical approach was a safe and effective strategy to tackle diffuse aortic thrombus with minimal morbidity and visceral embolization. Simultaneous aorto bi iliac bypass with thoracic endovascular aortic repair is a viable approach that can be undertaken with lesser morbidity and mortality risk as compared to complex and highly stressful total open surgical repair.
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BENLİ, Onur. "Akut Aortik Sendroma Genel Bakış." Arşiv Kaynak Tarama Dergisi 33, no. 1 (March 31, 2024): 1–15. http://dx.doi.org/10.17827/aktd.1246236.

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Akut aortik sendrom ; aort diseksiyonu , intramural hematom , semptomatik penetre aortik ülseri içine alan bir kavramdır. Ancak bu üç patoloji ilerleyişine göre torakal aort anevrizması ve travmatik aort rüptürünü de içine alarak geniş bir terminoloji grubunu oluşturur. Aort diseksiyonu en sık görülen tipidir. Tip A aort diseksiyonunda acil cerrahi gerekir iken, Tip B de endovascular tedavi gerekir. İntramural hematom, intimal flep olmadan aort duvarı hematomu olarak tanımlanmıştır. Rüptüre aorta , aort diseksiyonuna, anevrizma veya psödoanevrizmaya ilerleyebildiği gibi tam rezolüsyon da gösterebilir. Cerrahi ve prognostik olarak tutulan aort segmentine göre proksimal ( A tipi ) ve distal ( B tipi ) Akut Aortik Sendrom olarak ayrılabilir. A tipi İntramural hematomlarda çoğu olguda cerrahi tedavi önerilebilir. Desendan aortta lokalize İntramural hematomlarda cerrahi ve medikal tedavi ile yaşam süresinde genellikle fark bulunmamıştır. Penetran aortik ülser ise; internal elastik laminayı delerek media tabakasına ilerleyen aterosklerotik lezyonun ülserasyonunu tanımlar. Bu hastalarda klinik ilerleme olmayabilir. Travmatik aort rüptürü veya transeksiyon yine erken girişim gerektiren aort lezyonlarıdır. Tedavi yöntemleri, cerrahi ya da endovasküler girişimler hastaların klinik durumlarına göre ayarlanabilir.
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Dissertations / Theses on the topic "Aorta"

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Felter, Pierre-Loïc. "Creating hemodynamic atlas of aorta." Thesis, Linköpings universitet, Avdelningen för medicinsk teknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-142863.

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Turbulent blood flow is involved in the pathogenesis of several cardiovascular diseases. While it is known that turbulence is present in patients with obstructive disease in the major vessels, the magnitude and impact of turbulence in the normal heart and aorta is still relatively unexplored. Besides, existing analysis method of the blood flow is a labour intensive process and requires excessive amount of time. A method to automatically create hemodynamic atlases has been developed, using 4D Flow magnetic resonance imaging (MRI), a powerful tool to measure blood flow characteristics. The resulting atlases show the expected blood flow characteristics in the aorta for a group of similar subjects. Application of the method in healthy young and healthy old has shown significant differences in kinetic energy and turbulent kinetic energy in the aortic flow.
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Goulart, Gladstone. "Aneurisma de aorta abdominal roto." [s.n.], 2001. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312328.

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Orientador: Ana Terezinha Guillaumon
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
Made available in DSpace on 2018-07-31T15:08:36Z (GMT). No. of bitstreams: 1 Goulart_Gladstone_M.pdf: 10287445 bytes, checksum: 33d3b6d03f2c487d83f0162600995f42 (MD5) Previous issue date: 2001
Resumo: o presente estudo tem por finalidade estabelecer um programa de atendimento ao paciente do PS com dor abdominal aguda, suspeito de AAAR, para reduzir os graus de morbidade e mortalidade. Foram atendidos no PS do Hospital de Clínicas da Faculdade de Ciências Médicas na Unicamp, de janeiro de 1990 a dezembro de 1995, 23 pacientes com dores abdominais, sendo 20 homens e três mulheres com idade de 44 a 80. Seis pacientes (26,08%) tinham conhecimento da doença e 17 (73,91%) não tinham. Cinco pacientes (22%) foram encaminhados de outros hospitais com diagnóstico equivocado: cólica renal, pancreatite, patologias de coluna vertebral e lombalgia. Foram operados 18 pacientes (78,26%) de urgência e cinco pacientes (21,73%) de emergência. Dos cinco pacientes atendidos na emergência, quatro já tinham feito US, dois com TC e um paciente sem nenhum exame. Na urgência, oito pacientes (34,78%) fIZeramUS e 15 pacientes fizeram Te. Os 23 pacientes foram divididos em dois grupos: os que apresentavam quadro clínico de rotura e que foram atendidos no PS antes de 24h e os que foram atendidos após 24h. Dos 23 pacientes, sobreviveram dez (43,47%) com 56,52% de mortalidade. O infarto agudo do miocárdio foi a patologia que causou maior número de óbitos. A cirurgia para correção do AAAR mostrou que os pacientes atendidos na emergência com evolução clínica de rotura maior que 24h apresentaram melhor sobrevida no pós-operatório que os pacientes com evolução clínica de rotura menor que 24h. Os pacientes atendidos na urgência em comparação com os da emergência apresentaram uma melhor sobrevida no pós-operatório. Assim, conclui-se que quando houver forte suspeita clínica de AAAR, os pacientes devem ser encaminhados imediatamente à sala de operação. O paciente deve ser tratado cirurgicamente antes de transcorridas 24h do primeiro sintoma, considerando que o diagnóstico de AAAR é essencialmente clínico. Os pacientes admitidos no PS, com quadro clínico de abdome agudo devem ser submetidos à laparotomia exploratória, não se esquecendo de que pode ser AAART. Os pacientes com história de AAA serão submetidos à laparotomia para o tratamento da rotura do aneurisma. Os pacientes com mais de 60 anos de idade devem ser submetidos a exame de imagem para avaliar aorta e tratar profilaticamente o aneurisma antes da rotura
Abstract: The present study OOsthe objective of both establishing a nursing in the Emergency room (E.R) for patients suspected, of OOvingruptured abdominal aortic aneurysms (RAAA) and reducing the morbidity and mortality rates. Twenty-three patients with acute abdominal pain were operated on in the emergency room of Clinical Hospital in the Unicamp between January 1990 and December 1995: twenty men and three women with ages varying ftom 44 to 80. Six patients (26,08%) OOdprevious knowledge of their illness and 17 (73,91%) didn't OOveany. Five patients (22%) OOdcome from other hospitaIs with wrong diagnostic: renal pain, pancreatic and vertebral spine pathology. Eighteen patients (78,26%) underwent urgent surgery and five patients (21,73%) were operated on in the Emergency room (E.R). From these, four had already undergone US, two had done CT and one had no exams. In the Urgency room (D.R), eight patients (34,78%) had undergone US and fifteen OOddone CT. The patients were separated in two groups: those who presented clinical characteristics oí ruptured aneurysm and were hospitalized within 24h and the others afier 24h. From the total of 23 patients, 13 did not survive. The acute myocardial infarction was the pathology, which caused high mortality rates. CONCLUSION: l-Surgery to correct RAAA showed that patients were nursed into the Emergency room with clinical evolution of ruptured afier 24h, showed a better post-operative prognosis than patients of ruptured before 24h; 2-The patients were nursed in the Urgency room comparing with those of Emergency room, showed a better prognosis in the post-operative. So, we conclude tOOtwhen there is strong medical suspicion of RAAA, patients must be immediately taken to the operating room; 3-Patients must be surgically treated within 24h ofthe first syrnptoms, considering tOOthe RAAA diagnosis is essentially clinical; 4-Patients taken into the Emergency room, with acute abdominal pain ofunknown cause, must be submitted to a sound surgery, OOvingin mind tOOthe result can be that of a tamponed RAAA; S-Patients with AAA history will OOveto undergo on operation to correct the rupture of the aneurysm; 6-Patients over 60 must OOvethe aorta evaluated through CT or US and the aneurysm prophylatically treated to prevent rupturing. With the achieved results, a proposed protocol was elaborated, translated into the following algorithm: ...Note: The complete abstract is available with the full electronic digital thesis or dissertations
Mestrado
Cirurgia
Mestre em Cirurgia Medica
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Gimpel-Henning, Kristin [Verfasser]. "Auswirkung des Abklemmens der Aorta auf den endothelialen Schaden der Aorta ascendens / Kristin Gimpel-Henning." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2010. http://d-nb.info/1007466995/34.

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Iliopoulos, Jim St Vincent's Clinical School UNSW. "The aortic wrap procedure:a surgical method of treating agerelated aortic dilatation and stiffening." Awarded by:University of New South Wales. St Vincent's Clinical School, 2006. http://handle.unsw.edu.au/1959.4/28217.

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Introduction: There is progressive stiffening and dilatation of the aorta and large elastic arteries with aging as a result of the repetitive cyclic stress they are exposed to throughout life. Aortic stiffening has a number of detrimental effects including an increase in aortic pulse wave velocity and early wave reflection, isolated systolic hypertension, ventricular-vascular mismatch, impaired coronary blood flow reserve, and is the fundamental cause of heart failure in the elderly. The aim of this thesis is to provide proof of concept for the aortic wrap procedure; a surgical treatment of stiffening and dilatation of the ascending aorta with aging. The surgical procedure involves wrapping an elastic material around the ascending aorta of elderly patients, to reduce the stiffness and diameter of the ascending aorta towards that seen in youth. Methods: Proof of concept is investigated in the following studies. 1. The effect of the elastic wrap on the in-vivo stiffness of the normal aorta. 2. The effect of the elastic wrap on the in-vivo stiffness of the dilated and stiffened aorta. 3. The effect of the elastic wrap on the in-vitro stiffness of the aged human ascending aorta and on aortic pressure. 4. The effect of wrapping the aged human ascending aorta on pulse pressure (mathematical model). 5. The effect of chronic implantation on the structure of the normal aorta. 6. The mechanical properties of the ovine thoracic aorta and the elastic wrap material. Results: 1. Elastic wrap application increased the in-vivo stiffness of the normal aorta. 2. Elastic wrap application decreased the stiffness of the stiffened and dilated aorta. 3. Elastic wrap application decreased the in-vitro stiffness of the elderly human ascending aorta and pulse pressure. 4. A reduction in ascending aortic stiffness was sufficient to reduce ascending aortic pulse pressure. Conclusion: Application of the elastic wrap to the aged human ascending aorta is expected to reduce aortic stiffness, as well as systolic and pulse pressure, and to increase diastolic pressure with a reduction in cardiac load. The aortic wrap procedure may be an effective surgical procedure for the treatment of heart failure and isolated systolic hypertension.
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Troiano, Jéssica Antonini. "Papel das espécies reativas de oxigênio na hiporreatividade de aortas à fenilefrina observada no final da prenhez de Ratas Espontaneamente Hipertensas (SHR) /." Araçatuba, 2015. http://hdl.handle.net/11449/127836.

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Orientador: Cristina Antoniali Silva
Banca: Angelina Zanesco
Banca: Carlos Renato Tirapelli
Resumo: Estudos têm mostrado que em ratas prenhas normotensas ou hipertensas (SHR) há uma diminuição significativa da pressão arterial nos períodos finais da prenhez diretamente associada à redução da atividade simpática perivascular de leitos mesentéricos de ratas normotensas ou hipertensas (SHR). Essas alterações têm sido atribuídas a uma importante participação dos fatores relaxantes derivados do endotélio com destaque ao óxido nítrico (NO). Estudos recentes do nosso laboratório sugerem que o aumento da síntese de NO pela enzima óxido nítrico sintase endotelial (eNOS) ao final da prenhez ocorre por uma via menos dependente de cálcio, associada a fosforilação da eNOS em resíduos de Serina 1177, através da via PI3K/Akt/eNOS. Por outro lado, ratas hipertensas não prenhas apresentam uma disfunção endotelial e vascular ocasionada pelo aumento na produção de espécies reativas de oxigênio (ERO), sendo o complexo enzimático NAD(P)H oxidase, uma importante fonte de ERO. A produção de ERO modula a biodisponibilidade de NO. Assim, uma diminuição das ERO durante a prenhez poderia contribuir para a redução da PA e modulação da reatividade vascular, dependente do endotélio, aos agonistas vasoconstritores. Nossa hipótese é que em SHR prenhas, a redução da produção de ERO na aorta contribuiria para o aumento da biodisponibilidade do NO e para a hiporreatividade de aortas à fenilefrina (PE). Para isso, o estresse oxidativo sistêmico e da aorta (TBARS) foram avaliados em ratas Wistar e SHR, prenhas (P) e não prenhas (NP). Analisamos o efeito hipotensor da Apocinina (30 mg/kg) e do Tempol (30 mg/kg). Anéis intactos de aorta torácica de P e NP foram estimulados com PE antes e após incubação (30 min) com Apocinina (100 μmol/L) ou Tempol (0,1 nmol/L)...
Abstract: Studies have shown that in normotensive or hypertensive pregnant rats (SHR) there is a significant decrease in blood pressure in late pregnancy directly associated with the reduction in sympathetic perivascular activity of mesenteric beds of normotensive or hypertensive rats (SHR). These changes have been attributed to an important role of endothelium-derived relaxing factors especially to nitric oxide (NO). Recent studies in our laboratory suggest that increased synthesis of NO by endothelial nitric oxide synthase (eNOS) in late pregnancy is of a less calcium-dependent pathway associated with phosphorylation of eNOS on serine 1177 through via PI3K/Akt/ eNOS. On the other hand, do not exhibit a pregnant hypertensive rats and the vascular endothelial dysfunction caused by increased production of reactive oxygen species (ROS), the NAD(P)H oxidase enzyme complex, a major source of ROS. The ROS modulate the bioavailability of NO. Thus, a reduction of ROS during pregnancy could contribute to the reduction in blood pressure and modulation of vascular reactivity endothelium-dependent, to vasoconstrictor agonists. Our hypothesis is that in pregnant spontaneous hypertensive rats (SHR), the reduction of ROS production in the aorta contribute to increase the bioavailability of NO and hyporeactivity to aortae phenylephrine (PE). For this reason, systemic oxidative stress and aorta (TBARS) were valued in Wistar and SHR rats, pregnant (P) and non-pregnant (NP). We analyzed the hypotensive effect of Apocynin (30 mg/kg) and Tempol (30 mg/kg). Intact rings of thoracic aorta of P and NP were stimulated with PE before and after incubation (30 min) with apocynin (100 mmol/L) or Tempol (0,1 nmol/L)...
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6

Hueb, João Carlos [UNESP]. "Associação entre placa de aterosclerose em aorta torácica e alterações morfofuncionais cardíacas, em pacientes com acidente vascular cerebral." Universidade Estadual Paulista (UNESP), 2004. http://hdl.handle.net/11449/100789.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Placa de aterosclerose em aorta torácica é uma importante causa de acidente vascular cerebral (AVC) e ataque isquêmico transitório (AIT). Sua gênese estaria relacionada com migração, para a circulação cerebral, de trombos e cristais de colesterol que se desprenderiam de placas complexas, localizadas na aorta torácica proximal. Existem várias semelhanças entre a fisiopatologia do desenvolvimento da placa de aterosclerose e a remodelação miocárdica. Por causa disso, formulou-se a hipótese de que a avaliação de pacientes com AVC e AIT, por meio do ecocardiograma transtorácico ((ETT), pode identificar características associadas com risco aumentado de placa de aterosclerose em aorta. Os objetivos desse estudo foram: 1) avaliar a incidência de placa de aterosclerose em aorta torácica de pacientes com história de AVC e AIT prévios, por meio do ecocardiograma transesofágico (ETE); 2) avaliar se existe associação entre a presença dessas placas e sinais de remodelação ventricular, observados por meio do ETT; e, finalmente, 3) analisar os níveis séricos de proteína C reativa de alta sensibilidade (PCRas), nesses pacientes...
Atherosclerosis plaque in the thoracic aorta is an important cause of acute cerebrovascular events. It would be caused by migration of thrombi and cholesterol cristals released from complex plaques, located at the proximalis thoracic aorta, to the cerebral circulation. Because there are several similarities between the physiopathology of atherosclerosis plaque development and myocardial remodeling. We hypothesized that patients with cerebrovascular events, and atherosclerosis plaque have cardiac morpho-functional alterations. The objectives of the present study were: 1) to evaluate the incidence of thoracic aorta artherosclerosis plaques in patients with a previous cerebrovascular events history, by transesophageal echocardiogram (TEE); 2) to evaluate if there is an association between the presence of plaques and signs of ventricular remodeling, observed by means of transthoracic echocardiogram; and, 3) to analyze the high sensitivity C-reactive protein (hs-CRP) seric levels, in those patients. One hundred and sixteen patients (79 male) with a previous... (Complete abstract click electronic address below)
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Fonseca, Alyne Souza Félix. "Transplante de células de medula óssea (BMCs) de camundongos em modelo experimental para o desenvolvimento de aterosclerose: aspectos estruturais, ultraestrutuais e moleculares da aorta." Universidade do Estado do Rio de Janeiro, 2015. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=9524.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro
As células tronco são caracterizadas pela sua capacidade de se diferenciar em várias linhagens de células e exibir um pontente efeito parácrino. O objetivo deste trabalho foi avaliar o efeito da terapia com células da medula óssea (BMCs) na glicose sanguínea, no metabolismo lipídico e remodelamento da parede da aorta em um modelo experimental para aterosclerose. Camundongos C57BL/6 foram alimentados com uma dieta controle (grupo CO) ou uma dieta aterogênica (grupo AT - 60% gordura). Após 16 semanas, o grupo AT foi dividido em quatro sub grupos: grupo AT 14 dias e o grupo AT 21 dias receberam uma injeção de PBS na veia caudal e mortos 14 e 21 dias após respectivamente; grupo AT-BMC 14 dias e AT-BMC 21 dias que receberam uma injeção com BMCs na veia caudal e mortos 14 e 21 dias após, respectivamente. O grupo CO foi sacrificado juntamente com outros grupos. O transplante BMCs reduziu os niveis de glicose, triglicerídeos e colesterol total no sangue. Não houve diferença significativa em relação à massa corporal entre os grupos transplantados e não transplantados, sendo todos diferentes do grupo CO. Não houve diferença significativa na curva glicemica entre os grupos AT 14 dias, AT-BMC 14 dias e AT 21 dias e estes diferentes do grupo CO e do grupo AT-BMC 21 dias. O Qa (1/mm2) foi quantitativamente reduzido no grupo AT 14 dias e AT 21 dias quando comparado ao grupo CO. Este Qa se mostrou elevado no grupo AT-BMC 21 dias quando comparado a todos os grupos. O aumento da expessura da parede da aorta foi observado em todos os grupos aterogênicos, entretanto o aumento da espessura foi significativamente menor no grupo AT-BMC 21 dias em relação ao grupo AT 14 dias e AT 21 dias. A percentagem de fibras elásticas se apresentou significativamente maior no grupo AT 21 dias quando comparado ao CO e AT-BMC 21 dias. Não houve diferença significativa entre o grupo CO e AT-BMC 21 dias. Vacúolos na túnica média, delaminação e o adelgaçamento das lamelas elásticas foram observados nos grupos AT-14 dias e AT-21 dias. O menor número destes foi visualizado no grupo AT-BMC 14 dias e AT-BMC 21 dias. A imunomarcação para alfa actina de músculo liso (α-SMA) e fator de crescimento vascular e endotelial (VEGF) mostrou menor marcação em grupos transplantados com BMCs. A marcação para antígeno nuclear de proliferação celular (PCNA) mostrou-se mais expressiva no grupo AT-BMC 21 dias grupo. Marcação para CD105, CD133 e CD68 foi observada nos grupos AT 14 dias e AT 21 dias. Estas marcações não foram observadas nos grupos AT-BMC 14 dias e AT-BMC 21 dias. Nas eletromicrografias observamos o remodelamento benéfico no grupo AT-BMC14 dias e AT-BMC 21 dias, com a organização estrutural similar ao grupo CO. Vesículas de pinocitose, projeção da célula muscular lisa e a delaminação da lamina elástica interna são observados nos grupos AT 14 dias e AT 21 dias. Célula endotelial preservada, com lamina elástica interna de contorno regular e contínua é observada no grupo CO e nos grupos AT-BMC 14 dias e AT-BMC 21 dias. Como conclusão, os nossos resultados reforçam o conceito de que, em um modelo aterosclerótico utilizando camundongos e dieta aterogênica, a injeção de BMCs melhora os níveis de glicose, metabolismo lipídico e ocasiona um remodelamento benéfico na parede da aorta.
Stem cells are characterized by their ability to differentiate into multiple cell lineages and display the paracrine effect. The aim of this work was to evaluate the effect of therapy with bone marrow cells (BMCs) on blood glucose, lipid metabolism and aortic wall remodeling in mice through the administration of a high fat diet and subsequent BMCs transplantation. C57BL/6 mice were fed a control diet (CO group) or an atherogenic diet (AT group). After 16 weeks, the AT group was divided into four groups: an AT 14 days group and AT 21 days group, that were given an injection of vehicle and sacrificed at 14 and 21 days after, respectively; AT-BMC 14 days group and AT-BMC 21 days group that was given an injection of BMCs and sacrificed at 14 and 21 days after. The CO group was sacrificed along with other groups. The BMCs transplant had reduced blood glucose, triglycerides and total cholesterol. There was no significant difference in relation to body mass between the transplanted groups and non-transplanted groups, with all are different to CO group. There was no significant difference in the glycemic curve between AT 14 days group, AT-BMC 14 days group and AT 21 days group and these are different to CO and the AT-BMC 21 days group. The Qa (1 / mm2) was quantitatively reduced in the AT 14 days group and AT 21 days group when compared to the CO group. This Qa proved high in AT-BMC 21 days BMC compared to all groups. The increased thickness of the aortic wall was observed in all atherogenic groups, but was significantly smaller in group AT-BMC 21 days compared to AT 14 days group and AT 21 days group. The percentage of elastic fibers was significantly higher in the AT 21 days group when compared to the CO and AT-BMC 21 days. There was no significant difference between the CO and AT-BMC 21 days. Vacuoles in the media tunic, delamination and the thinning of the elastic lamellae were observed in AT 14 days group and AT 21 days group. The smallest number of these apresentation were displayed on the AT-BMC 14 days group and and AT-BMC 21 days. The immunostaining for α-SMA and VEGF showed lower in AT-BMC 14 days group and AT-BMC 21 days group. The markup for PCNA appears to be greater in the AT-BMC 21 days group. Marking to CD105, CD133 and CD68 were observed in AT 14 days group and AT 21 days group. These markings were not observed in AT-BMC 14 days group and AT-BMC 21 days group. In electron micrographs observed the beneficial remodeling in AT-BMC 14 day group and AT-BMC 21 days, with the structural organization was similar to the CO group. Vesicles of pinocytosis, projection of smooth muscle cell and delamination of the internal elastic lamina are seen in groups AT 14 days group and AT 21 days group. Endothelial cell preserved, regular and continuous contour in internal elastic lamelae is observed in the CO group, AT-BMC 14 days group and AT-BMC 21 days group. In conclusion, our results support the concept that an atherosclerotic model using mice and atherogenic diet, the injection of BMCs improve glucose, lipid metabolism and causes a beneficial remodeling of the aortic wall.
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Lain, Vinícius Victorazzi. "Avaliação em médio prazo da pressão intra-saco após correção endovascular de aneurisma de aorta abdominal com o uso de sensor sem fio." Florianópolis, 2010. http://repositorio.ufsc.br/handle/123456789/103247.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências Médicas.
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Justificativa: O objetivo do tratamento endovascular do aneurisma de aorta abdominal é a exclusão do saco aneurismático da circulação sistêmica. Para acompanhar a eficácia do tratamento é necessária a realização de angiotomografias seriadas. A monitorização continuada da pressão poderia diagnosticar precocemente casos em que esteja ocorrendo falha desse tratamento, auxiliando ou substituindo a tomografia. Objetivo: Avaliar a eficácia em médio prazo da medida de pressão através de sensor sem fio implantado no saco aneurismático após tratamento endovascular de aneurisma de aorta abdominal (AAA). Desenho do Estudo: Quarenta pacientes submetidos a tratamento endovascular de aneurisma de aorta abdominal receberam implante de sensor sem fio para monitorização em médio prazo da pressão intra-saco. Os dados foram analisados no primeiro, sexto, décimo segundo meses e anualmente. A cada análise, uma angiotomografia informava o diâmetro do aneurisma, presença e tipo de vazamento. A pressão arterial sistêmica assim como todos os dados pressóricos obtidos através do sensor foram coletados. Resultados: No seguimento, dos 40 sensores implantados apenas em dois o sinal não pode ser detectado. A pressão de pulso obtida apresentou boa sensibilidade em afastar a presença de vazamento quando inferior a 25mmHg no primeiro ano. Após esse período, o Índice de Endotensão mostra-se como a variável que mais se aproxima dos dados tomográficos. Na presença de vazamantos tipo I ou III, o sensor é capaz de identificar sucesso ou falha após a correção do vazamento. Até o segundo ano de seguimento, resultados apresentados pelo sensor são concordantes com dados tomográficos, a partir daí, perdem acurácia. Conclusão: Na amostra estudada não foi possível obter sensibilidade suficiente para substituir a realização da tomografia no acompanhamento dos AAA tratados por técnica endovascular. Um maior número de pacientes é necessário para estabelecer o verdadeiro papel da monitorização pressórica sem fio no seguimento do tratamento endovascular do aneurisma de aorta abdominal.
Racional: The objective of endovascular treatment of an abdo-minal aortic aneurysm is to exclude the aneurysm sac from systemic circulation. In order to assess treatment effectiveness it is necessary to perform serial computed tomography (CT). Continued pressure moni-toring could provide an early diagnosis of cases in which this treatment is failing, helping or replacing CT. Objective: Evaluation of medium-term effectiveness of pressure measurement using a wireless sensor implanted in the aneurysm sac after endovascular treatment of abdominal aortic aneurysm. Method: Forty patients undergoing endovascular treatment for abdominal aortic aneurysm had a wireless sensor implanted for medium-term monitoring of intrasac pressure. The data were analyzed in the first, sixth and twelfth month and annually. At each analysis, a CT scan in-formed the aneurysm diameter, presence and risk of endoleaks. System-ic arterial pressure was collected, as well as all pressure data obtained through the sensor. Results: Of the 40 sensors implanted, the signal could not be de-tected only in two. The pulse pressure obtained presented good sensitivi-ty to rule out the presence of leakage when it was less than 25mmHg during the first year. After this period, the Endotension Index is the variable that comes closest to the CT scan data. With type I or III endo-leaks, the sensor can identify success or failure after endoleak repair. Until the second year of follow up, the results presented by the sensor agree with CT data, and then become less accurate. Conclusions: In the sample studied sufficient sensitivity could not be achieved to replace the CT when following AAA treated by the en-dovascular technique. A larger number of patients is needed to deter-mine the true role of wireless pressure monitoring when following en-dovascular treatment of abdominal aortic aneurysm.
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Bauer, Matthias. "Bikuspide Aortenklappe und Dilatation der Aorta ascendens." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=974923877.

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Eazzetta, Benedict A. "Flow visualization of the human abdominal aorta." Thesis, Georgia Institute of Technology, 1987. http://hdl.handle.net/1853/17800.

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Books on the topic "Aorta"

1

Chiesa, Roberto, Germano Melissano, and Alberto Zangrillo, eds. Thoraco-Abdominal Aorta. Milano: Springer Milan, 2011. http://dx.doi.org/10.1007/978-88-470-1857-0.

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Williams, G. Melville. Atlas of aortic surgery. Baltimore: Williams & Wilkins, 1996.

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Dieter, Robert S., Raymond A. Dieter, and Raymond A. Dieter III, eds. Diseases of the Aorta. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-11322-3.

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Schlosser, V., and G. Fraedrich, eds. Aneurysmen der thorakalen Aorta. Heidelberg: Steinkopff, 1990. http://dx.doi.org/10.1007/978-3-642-93672-2.

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1932-, Lindsay Joseph, ed. Diseases of the aorta. Malvern, Pa: Lea & Febiger, 1994.

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Carbone, Iacopo, Davide Farina, Pier Giorgio Nardis, and Davide Bellini, eds. Imaging of the Aorta. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-52527-8.

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Harisios, Boudoulas, Toutouzas P. K, and Wooley Charles F, eds. Functional abnormalities of the aorta. Armonk, N.Y: Futura Pub., 1996.

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Rückert, Ralph I., Wolfgang Hepp, and Bernd Luther, eds. Chirurgie der abdominalen und thorakalen Aorta. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-11719-0.

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Luther, Bernd, Ralph I. Ru ckert, and Wolfgang Ru diger Hepp. Chirurgie der abdominalen und thorakalen Aorta. Berlin: Springer-Verlag, 2010.

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Stoney, Ronald J. Wylie's atlas of vascular surgery. Philadelphia: J.B. Lippincott Co., 1992.

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Book chapters on the topic "Aorta"

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Bartolozzi, Carlo, Emanuele Neri, Irene Bargellini, and Claudia Gianni. "Aorta." In 3D Image Processing, 147–60. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-59438-0_14.

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Vegas, Annette, Massimiliano Meineri, and Angela Jerath. "Aorta." In Real-Time Three-Dimensional Transesophageal Echocardiography, 171–81. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4614-0665-5_7.

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Bährle-Rapp, Marina. "Aorta." In Springer Lexikon Kosmetik und Körperpflege, 42. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_729.

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Gedroyc, Wladyslaw, and Sheila Rankin. "Aorta." In Practical CT Techniques, 14–19. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-3275-2_5.

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Vegas, Annette. "Aorta." In Perioperative Two-Dimensional Transesophageal Echocardiography, 199–217. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-60902-7_9.

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Hangay, George, Severiano F. Gayubo, Marjorie A. Hoy, Marta Goula, Allen Sanborn, Wendell L. Morrill, Gerd GÄde, et al. "Aorta." In Encyclopedia of Entomology, 190–91. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_10276.

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Spittell, Peter C., Anjali Bhagra, and Sharon L. Mulvagh. "Aorta." In Atlas of Handheld Ultrasound, 121–26. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-73855-0_23.

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Eisenberg, Ronald L. "Aorta." In What Radiology Residents Need to Know: Chest Radiology, 247–55. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16826-1_18.

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Vegas, Annette. "Aorta." In Perioperative Two-Dimensional Transesophageal Echocardiography, 137–49. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-9952-8_6.

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Lichtenstein, Daniel A. "Aorta." In Whole Body Ultrasonography in the Critically Ill, 83–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-05328-3_11.

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Conference papers on the topic "Aorta"

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Murray, Alastair, and Ewan Crawford. "Compute Aorta." In IWOCL '20: International Workshop on OpenCL. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3388333.3388652.

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Karagiozis, Kostas, Marco Amabili, Rosaire Mongrain, Raymond Cartier, and Michael P. Pai¨doussis. "Human Aorta Buckling Related to Dissection." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-39498.

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Human aortas are subjected to large mechanical stresses and loads due to blood flow pressurization and through contact with the surrounding tissue and muscle. It is essential that the aorta does not lose stability for proper functioning. The present work investigates the buckling of human aorta relating it to dissection by means of an analytical model. A full bifurcation analysis is used employing a nonlinear model to investigate the nonlinear stability of the aorta conveying blood flow. The artery is modeled as a shell by means of Donnell’s nonlinear shell theory retaining in-plane inertia, while the fluid is modelled by a Newtonian inviscid flow theory but taking into account viscous stresses via the time-averaged Navier-Stokes equation. The three shell displacements are expanded using trigonometric series that satisfy the boundary conditions exactly. A parametric study is undertaken to determine the effect of aorta length, thickness, Young’s modulus, and transmural pressure on the nonlinear stability of the aorta. As a first attempt to study dissection, a quasi-steady approach is taken, in which the flow is not pulsatile but steady. The effect of increasing flow velocity is studied, particularly where the system loses stability, exhibiting static collapse. Regions of large mechanical stresses on the artery surface are identified for collapsed arteries indicating possible ways for dissection to be initiated.
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Parenti, C., K. Laksari, M. Shafieian, and K. Darvish. "Multilayer properties of aorta." In 2009 IEEE 35th Annual Northeast Bioengineering Conference. IEEE, 2009. http://dx.doi.org/10.1109/nebc.2009.4967638.

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Sasaki, Michihiko. "Percutaneous angioscopy of aorta." In OE/LASE'93: Optics, Electro-Optics, & Laser Applications in Science& Engineering, edited by Abraham Katzir. SPIE, 1993. http://dx.doi.org/10.1117/12.146340.

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Shakir, Z., A. Rhodes, S. Sarva, and R. Kesavan. "Total Eclipse of the Aorta: A Novel Case of Spontaneous Abdominal Aorta Thrombosis." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6687.

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Karagiozis, Kostas, Marco Amabili, Rosaire Mongrain, Raymond Cartier, and Michael P. Pai¨doussis. "Buckling of Human Aorta Related to Dissection due to Flow-Pressure Conditions." In ASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting collocated with 8th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-30812.

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Human aortas are subjected to large mechanical stresses and loads due to blood flow pressurization and through contact with the surrounding tissue and muscle. It is essential that the aorta does not lose stability for proper functioning. The present work investigates the buckling of human aorta relating it to dissection by means of an analytical model. A full bifurcation analysis is used employing a nonlinear model to investigate the nonlinear stability of the aorta conveying blood flow. The artery is modeled as a shell by means of Donnell’s nonlinear shell theory retaining in-plane inertia, while the fluid is modelled by a Newtonian inviscid flow theory but taking into account viscous stresses via the time-averaged Navier-Stokes equation. The three shell displacements are expanded using trigonometric series that satisfy the boundary conditions exactly. A parametric study is undertaken to determine the effect of aorta length, thickness, Young’s modulus, and transmural pressure on the nonlinear stability of the aorta. As a first attempt to study dissection, a quasi-steady approach is taken, in which the flow is not pulsatile but steady. The effect of increasing flow velocity is studied, particularly where the system loses stability, exhibiting static collapse. Regions of large mechanical stresses on the artery surface are identified for collapsed arteries indicating possible ways for dissection to be initiated.
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Haslach, Henry W., Jonathan Chung, and Aviva Molotsky. "Fracture Mechanisms in Bovine Aorta." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19366.

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Rupture of vascular tissue in the circulatory system under non-impact loading is involved in potentially life threatening events such as Marfan’s syndrome or rupture of small renal veins during shock wave lithotripsy. The rupture mechanisms are not well-understood. The complexity of the artery wall precludes the use of rupture theories invented for metals or for fibered composites with a homogeneous matrix. Artery tissue is composed of ground material, smooth muscle cells, elastin and collagen. The collagen fibers, which are generally circumferentially oriented, are the load carrying material after large deformations. Clark and Glagov [1] propose that the media of an elastic artery is built of musculo-elastic fascicles made up of a layer of circumferentially oriented SMC that lie parallel and between two elastin lamellae. Between the elastin sheets of adjacent elements are interspersed collagen fiber bundles.
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Tang, G. C., W. B. Wang, Y. Pu, and R. R. Alfano. "Optical birefringence of aorta tissues." In BiOS, edited by Robert R. Alfano. SPIE, 2010. http://dx.doi.org/10.1117/12.842951.

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Meadley, Stacey L., Umakanta Tripathy, Paul W. Wiseman, and Richard L. Leask. "Multiphoton Microscopy of Healthy and Aneurismal Human Ascending Aorta." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206152.

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The ascending aorta (AA) is the largest artery in the human body. It is responsible for transporting blood between the heart and the rest of the body. The structure of the AA allows it to withstand the resulting blood flow forces. This unique structure is due primarily to the proteins collagen and elastin. Collagen accounts for the strength of the aorta while the mechanical properties of the tissue, under healthy physiological conditions, is dominated by the elastin. Aneurysms are the primary disease associated with the AA, where the diameter of the vessel increases over 1.5 times its original size. Aneurysms can result in severe blood flow disturbances or rupture of the AA and almost always require surgical intervention. The development of an aneurysm is due to a weakening of the aortic wall, specifically the degradation of the structural proteins. This study examines the changes that occur to collagen and elastin in the ascending aorta with aneurysms using multiphoton microscopy. Specifically, the orientation of collagen fibers and the morphology of the fenestrations in the elastic lamina are compared between healthy and dilated human ascending aortas.
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Agianniotis, Aristotelis, Alexander Rachev, and Nikos Stergiopulos. "Active Axial Stress in Mouse Aorta." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80102.

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Arteries exhibit a complex mechanical behavior due to their complex structure and composition. When smooth muscle cells (SMCs) are stimulated to contract, an artery constricts and develops the so called active stress in the arterial wall. Assuming that the SMCs are oriented in the circumferential direction most of studies consider solely development of the circumferential active stress [1]. However, histological findings show existence of SMCs oriented in both the circumferential and axial direction; these vessels manifest biaxial contractile response [2, 3]. In this study we also observed biaxial contractile response and processed the experimental data to incorporate an active axial stress in the constitutive formulation of the arterial tissue.
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Reports on the topic "Aorta"

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Marcillo Calderón, Cristian Fernando, José Carlos Sánchez Vega, and José Andrés Uribe Múnera. Aneurisma de aorta abdominal: conceptos claves para el médico general. Facultad de Medicina Universidad de Antioquia, August 2023. http://dx.doi.org/10.59473/medudea.pc.2023.20.

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Paciente de 60 años, sexo masculino, quien consultó por dolor lumbar continuo de vieja data, el cual aumentaba con los movimientos del tronco, al pararse, y agacharse. Como antecedentes: hipertensión arterial con tratamiento adecuado y tabaquismo activo (30 paquete/años). Al examen físico con signos vitales normales, abdomen sin alteraciones importantes, pulsos presentes en las 4 extremidades, dolor al palpar región lumbar bilateral.
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Mateos Colino, Alfonso, Rafael Gólpe Gómez, and Nieves Gonzalez Vidal. Disnea y Derrame Pleural Izquierdo Masivo como Presentación De Disección de Aorta Descendente. Buenos Aires: siicsalud.com, March 2010. http://dx.doi.org/10.21840/siic/111908.

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Granata, Joseph, Hugo Sanchez, Phillip Loeschinger, and Jodi Evans. CD105 Deficiency in Mouse Aorta-Derived Progenitor Cells Promotes an Enhanced Inflammatory Response to Lipopolysaccharide. Journal of Young Investigators, October 2018. http://dx.doi.org/10.22186/jyi.35.4.61-66.

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Zhang, Jing. Platelet-Derived Growth Factor-BB Stimulates Fibronectin Gene Expression in Fibroblasts Isolated from Rat Thoracic Aorta. Fort Belvoir, VA: Defense Technical Information Center, May 1994. http://dx.doi.org/10.21236/ad1011392.

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Wang, Ting-Wei, Yun-Hsuan Tzeng, Jia-Sheng Hong, Ho-Ren Liu, Kuan-Ting Wu, Huan-Yu Hsu, Hao-Neng Fu, Yung-Tsai Lee, Wei-Hsian Yin, and Yu-Te Wu. Deep Learning Approaches for Aorta Segmentation in Computed Tomography Imaging: A Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2024. http://dx.doi.org/10.37766/inplasy2024.3.0121.

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Ma, Yunpeng, Yinzun Qi, Qiang Li, Wenjie Zhao, Shuangxiong Zhu, Yu Zhang, and Xin Chen. Endovascular repair versus best medical treatment for uncomplicated acute type B acute aorta dissection: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2023. http://dx.doi.org/10.37766/inplasy2023.8.0038.

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Alshammari, Mohammed Kanan. Efficacy of Complementary and Alternative Medicine in Peripheral Arterial Disease: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2023. http://dx.doi.org/10.37766/inplasy2023.3.0001.

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Review question / Objective: To explore various CAM therapies available and to generate evidence that these therapies are effective for managing the disease. Condition being studied: Peripheral arterial disease (PAD) is described as the atherosclerotic process of arteries other than cerebral and coronary arteries i.e. the abdominal aorta, iliac, and arteries of the lower limb which leads to the narrowing and blocking of arteries. Information sources: An online systematic literature search will be done from the time of database inception from 5 electronic databases namely PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Ovid SP, ISI Web of Science, Elsevier Science Direct, and Wiley Online Library.
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Bottino, Mattia. ECMI Minorities Blog. Francophone, Francophile, and Gallo-Romance peripheries in Piedmont and the Aosta Valley. European Centre for Minority Issues, November 2023. http://dx.doi.org/10.53779/alpj4698.

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The blog post discusses the linguistic and cultural peculiarities of Piedmont and the Aosta Valley, two regions that have historically straddled France and Italy. It provides a brief historical linguistic overview of the development of Gallo-Romance languages (French, Franco-Provençal, and Occitan) in these regions. The piece describes the Francophile and Francophone orientation of Piedmont throughout its history, as well as the belated introduction of Tuscan (Italian). It stresses the singularity of Piedmontese, and its close linguistic relation to neighbouring Gallo-Romance languages. Against this background, the text assesses the current state and vitality of Franco- and Gallo-Romance peripheries within the borders of Italy, and explains how such identities have evolved, been reshaped or become politicized. Primordialist and constructivist perspectives on national (and minority) identities are combined to better understand the development, decay, and reconfiguration of linguistic and cultural identities in Piedmont and the Aosta Valley.
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Fire fighter/paramedic suffers a dissection of his aorta while participating in physical fitness training - Texas. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, October 2006. http://dx.doi.org/10.26616/nioshfffacef200523.

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