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1

Zhou, Xiang, Zhouhan Wen, Lili Zhou, Ying Ge, and Yuhao Yang. "Sports Rehabilitation Base in Natural Environment Helps College Students' Psychological Anxiety." Frontiers in Humanities and Social Sciences 2, no. 11 (November 21, 2022): 390–99. http://dx.doi.org/10.54691/fhss.v2i11.2928.

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For the growing number of college students with anxiety, how to help college students control anxiety or cope with anxiety has become the focus of social and mental health research. Through the questionnaire data on college students' anxiety factors and the analysis of the treatment methods for the corresponding symptoms in China, we can learn that there are some drawbacks in the common anxiety symptoms of college students and the existing treatment methods for middle and low levels of psychological anxiety in China. Therefore, based on the results of relevant papers, our team summarized several relevant research on treatment methods, synthesized two more effective treatment methods, put forward the idea of "setting up a base in an outdoor natural environment, and then carrying out aerobic exercise", and established the feasibility of Huaiyuan County's environment through the evaluation of relevant indicators and the field survey of the scheduled treatment sites, It also predicts that aerobic exercise in the base set up in the outdoor natural environment has practical effect on the treatment of psychological anxiety.
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2

Jiang, Qi, Xinshu She, Sarah-Eve Dill, Sean Sylvia, Manpreet Kaur Singh, Huan Wang, Matthew Boswell, and Scott Rozelle. "Depressive and Anxiety Symptoms among Children and Adolescents in Rural China: A Large-Scale Epidemiological Study." International Journal of Environmental Research and Public Health 19, no. 9 (April 20, 2022): 5026. http://dx.doi.org/10.3390/ijerph19095026.

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Although children living in low- and middle-income countries (LMICs) account for 90% of the global population of children, depression, and anxiety among children in LMICs have been understudied. This study examines the prevalence of depression and anxiety and their associations with biological and psychosocial factors among children across China, with a focus on rural areas. We conducted a large-scale epidemiological study of depression and anxiety among 53,421 elementary and junior high school-aged children across China. The results show that 20% are at risk for depression, 6% are at risk for generalized anxiety, and 68% are at risk for at least one type of anxiety. Girls and junior high school students show a higher risk for both depression and anxiety symptoms, while socioeconomic status has varying associations to depression and anxiety symptoms. Our results also show consistent correlations between depression and anxiety symptoms and standard math test scores. These findings underscore the importance of identification, prevention, and treatment of youth depression and anxiety in underdeveloped areas. As China constitutes 15% of the global population of children under age 18, this study offers valuable information to the field of global mental health.
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Zhang, L., Y. L. He, H. Ma, Z. N. Liu, F. J. Jia, and M. Y. Zhang. "FC30-06 - Prevalence of depressive - anxiety disorders of gastroenterology outpatients in five cities cross China." European Psychiatry 26, S2 (March 2011): 1988. http://dx.doi.org/10.1016/s0924-9338(11)73691-4.

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IntroductionDepression and anxiety disorders are prevalent mental disorders in China. But some those patients do not seek help from psychiatrists firstly but see internists first.Objectives and aimsThis study aimed to investigate the prevalence of depressive - anxiety disorders in gastroenterology outpatients and assess the detection rate provided by physicians in China.MethodsA multicenter, hospital-based cross-sectional study was carried on in the 15 large general hospitals of five cities cross China. A total of 1995 gastroenterological outpatients were screened by Hospital Anxiety and Depression Scale (HADS). Subjects whose HADS scores ≥ 8 were interviewed by psychiatrists, using Mini International Neuropsychiatric Interview (M.I.N.I) to make further diagnoses. Physicians’ diagnoses and treatment were recorded.ResultsThe adjusted prevalence of depressive disorder and anxiety disorders was 14.39% and 9.42% respectively.ConclusionsThe prevalence of depressive-anxiety disorder is high in gastroenterology outpatients in China, which suggests the related training of detecting these mental disorders is needed to gastroenterologists.
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Guan, Hongyu, Huan Wang, Kang Du, Jin Zhao, Matthew Boswell, Yaojiang Shi, and Yiwei Qian. "The Effect of Providing Free Eyeglasses on Children’s Mental Health Outcomes in China: A Cluster-Randomized Controlled Trial." International Journal of Environmental Research and Public Health 15, no. 12 (December 5, 2018): 2749. http://dx.doi.org/10.3390/ijerph15122749.

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If children with common vision problems receive and use eyeglasses, their educational performance rises. Without proper treatment, visually impaired children may not achieve educational gains and could suffer from poor mental health. We use a randomized controlled trial to study the impact of an eyeglasses promotion program in rural China on the mental health of myopic primary school students. Three measures of mental health are used: learning anxiety, physical anxiety, and scores on the Mental Health Test (MHT). Our empirical analysis showed that on average, the treatment has small and insignificant for learning anxiety and MHT, and a small but significant reduction in physical anxiety. However, subgroup analysis reveals that myopic students who study more intensively see their learning anxiety and physical anxiety reduced after being provided with eyeglasses. In contrast, students with the lower study intensity suffer a rise in learning anxiety after receiving eyeglasses. A potential mechanism for the differing impacts is the increase in teasing reported among low study-intensity students that does not occur for high study-intensity students. Care should be taken to maximize the benefits and minimize the costs of in-school vision programs.
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Chen, Huijing, Marcus A. Rodriguez, Mingyi Qian, Tomoko Kishimoto, Muyu Lin, and Thomas Berger. "Predictors of treatment outcomes and adherence in internet-based cognitive behavioral therapy for social anxiety in China." Behavioural and Cognitive Psychotherapy 48, no. 3 (January 13, 2020): 291–303. http://dx.doi.org/10.1017/s1352465819000730.

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AbstractBackground:Although internet-based cognitive behaviour therapy (ICBT) is an effective treatment for social anxiety disorder (SAD), a substantial proportion of patients do not achieve clinically significant improvement. More research is needed to identify which factors predict treatment adherence and outcomes.Aims:The aims of this study were to (1) identify demographic and clinical factors associated with treatment adherence and outcomes in ICBT for social anxiety in China, and (2) explore whether low-intensity therapist support results in improved treatment adherence or outcomes.Method:Participants were assigned to either therapist-guided (N = 183) or self-guided ICBT (N = 72). Level of social anxiety was measured at both pre- and post-treatment. Treatment adherence and outcomes were analysed using a two-step linear and logistic regression approach. Clinical and demographic characteristics were examined.Results:No significant group differences were found for treatment adherence or outcomes between the therapist-guided and self-guided conditions. Participants diagnosed with SAD were significantly less likely to drop out (OR 0.531, p = .03) compared with subclinical participants with social anxiety symptoms. Older participants (B = 0.17, SE = 0.04, p = .008) and participants with a diagnosis of SAD (B = 0.16, SE = 0.44, p = .01) tended to complete more modules. Participants who completed more modules (B = 0.24, SE = 0.03, p = .01) and participants who identified as female (B = –0.20, SE = 0.18, p = .04) reported greater reductions in SAD symptoms.Conclusions:Understanding of factors related to adherence and outcome is necessary to prevent drop-out and optimize outcome.
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6

Fan, Jiaqi. "The Effectiveness of Cognitive Behavioral Therapy on Social Anxiety in China." Journal of Education, Humanities and Social Sciences 1 (July 6, 2022): 404–9. http://dx.doi.org/10.54097/ehss.v1i.756.

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This article’s purpose is to discover the effectiveness of Cognitive Behavioral Therapy on patients who are diagnosed with Social Anxiety Disorder or people who have high anxiety levels in China. Chinese adolescents have higher anxiety levels that have than adolescents in other countries, and the information about social anxiety and the effectiveness of CBT is not sufficient. In order to find the relationships between CBT and SAD patients in China, this article collected 13 pieces of research that contain information about the effectiveness of CBT and SAD. There is strong evidence that cognitive-behavioral therapy treatment was effective in the Chinese SAD participants. The shame proneness will influence the effectiveness of CBT. The lower the feeling of shame and self-directed attention the patients have, the more effective the CBT will be for the SAD patients. Also, the language used during the CBT session for SAD patients is significant. CBT may be more effective if the language used is the most familiar language that SAD patients speak. However, more research is needed to find further correlations.
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7

Liu, H., L. Wang, and J. Gao. "Prevalence and predictors of anxiety and depression after breast cancer treatment in North China." Breast 44 (March 2019): S94. http://dx.doi.org/10.1016/s0960-9776(19)30329-7.

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8

Zhang, Yalin, Derson Young, Sing Lee, Honggen Zhang, Zeping Xiao, Wei Hao, Yongmin Feng, Hongxiang Zhou, and Doris F. Chang. "Chinese Taoist Cognitive Psychotherapy in the Treatment of Generalized Anxiety Disorder in Contemporary China." Transcultural Psychiatry 39, no. 1 (March 2002): 115–29. http://dx.doi.org/10.1177/136346150203900105.

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9

Yue, Ling, Jingyi Wang, Mingliang Ju, Yi Zhu, Lianghu Chen, Lin Shi, Bohai Shi, Jun Chen, and Yifeng Shen. "How psychiatrists coordinate treatment for COVID-19: a retrospective study and experience from China." General Psychiatry 33, no. 4 (July 2020): e100272. http://dx.doi.org/10.1136/gpsych-2020-100272.

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BackgroundPatients with COVID-19 are at high risk of developing mental health problems; however, the prevalence and management of mental disorders and how psychiatrists coordinate the treatment are unclear.AimsWe aimed to investigate the mental health problems of patients infected with COVID-19 and to identify the role of psychiatrists in the clinical treatment team during the pandemic. We also share the experience of psychiatric consultations of patients with COVID-19 in Shanghai, China.MethodsWe analysed data from the psychiatric medical records of 329 patients with COVID-19 in the Shanghai Public Health Clinical Center from 20 January to 8 March 2020. We collected information including sociodemographic characteristics, whether patients received psychiatric consultation, mental health symptoms, psychiatric diagnoses, psychiatric treatments and severity level of COVID-19.ResultsPsychiatric consultations were received by 84 (25.5%) patients with COVID-19. The most common symptoms of mental health problems were sleep disorders (75%), anxiety (58.3%) and depressive symptoms (11.9%). The psychiatric consultation rate was highest in critically ill patients (69.2%), with affective symptoms or disturbed behaviour as their main mental health problems. Psychiatric diagnoses for patients who received consultation included acute stress reaction (39.3%), sleep disorders (33.3%), anxiety (15.5%), depression (7.1%) and delirium (4.8%). In terms of psychiatric treatments, 86.9% of patients who received psychiatric consultation were treated with psychotropic medications, including non-benzodiazepine sedative-hypnotic agents (54.8%), antidepressants (26.2%), benzodiazepines (22.6%) and antipsychotics (10.7%). Among the 76 patients who were discharged from the hospital, 79% had recovered from mental health problems and were not prescribed any psychotropic medications. The symptoms of the remaining 21% of patients had improved and they were prescribed medications to continue the treatment.ConclusionsThis is the first study to report psychiatric consultations for patients with COVID-19. Our study indicated that a considerable proportion of patients with COVID-19, especially critically ill cases, experienced mental health problems. Given the remarkable effect of psychiatric treatments, we recommend that psychiatrists be timely and actively involved in the treatment of COVID-19.
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10

Lin, Ling-Yu, Kan Wang, Tomoko Kishimoto, Marcus Rodriguez, Mingyi Qian, Yin Yang, Qingxue Zhao, Thomas Berger, and Chenghua Tian. "An Internet-Based Intervention for Individuals With Social Anxiety and Different Levels of Taijin Kyofusho in China." Journal of Cross-Cultural Psychology 51, no. 5 (May 21, 2020): 387–402. http://dx.doi.org/10.1177/0022022120920720.

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The aim of the present study is to investigate the efficacy of internet-based cognitive behavior therapy (ICBT) for individuals with social anxiety (SA) and different levels of Taijin Kyofusho (TKS) in China. The ICBT program was translated into Chinese with some specific contents adapted for Chinese culture. Participants ( N = 80) with SA were assigned either to a treatment ( n = 55) or control group ( n = 25). Both groups were further divided into subgroups, based on their Taijin Kyofusho Scale (TKSS) scores. Participants in the ICBT treatment group reported significant posttreatment reductions in Social Interaction Anxiety Scale and Social Phobia Scale scores, relative to participants in the control group. In addition, participants in the treatment group with higher pretreatment TKS levels showed significantly greater reductions in TKSS scores. Results suggest that ICBT is a promising approach for the treatment of individuals with SA both with and without features of TKS. Clinical and cross-cultural implications, mechanisms of change, limitations, and future directions are discussed.
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11

Lin, Jin, Yue Ji, Jinhua Si, Guanran Wang, Xinju Li, and Li Shen. "Evaluation of the Safety and Efficacy of Xiao Yao San as a Treatment for Anxiety: A Systematic Review and Meta-Analysis." Evidence-Based Complementary and Alternative Medicine 2022 (April 6, 2022): 1–10. http://dx.doi.org/10.1155/2022/1319592.

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Objective. Xiaoyao San (XYS) is a medicinal preparation that is commonly employed in China for the treatment of anxiety disorders (AD). Despite suggestions that it may offer certain advantages in this context, there are no reliable evidence-based studies regarding its efficacy at present. The present study was developed to gauge the efficacy and safety of XYS for the treatment of AD in a systematic manner. Methods. PubMed, the Cochrane Library, EMBASE, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang database, Weipu database, and China Biomedical Documentation Service System (CBM) databases were systematically searched for all randomized control trials (RCTs) evaluating the use of XYS for the treatment of AD published as of November 2021. Two investigators independently screened all studies, extracted data, and assessed the risk of bias for included studies using RevMan5.3. Results. In total, 9 RCTs incorporating 809 patients were included in the present meta-analysis, of which 3 compared oral XYS to anxiolytic treatment and 6 compared oral XYS + anxiolytics to anxiolytic treatment alone. The resultant meta-analysis revealed that XYS alone or in combination with anxiolytic treatment was associated with better improvements in anxiety-related symptoms and reduced adverse drug-related reactions as compared to anxiolytic treatment alone. Conclusion. The available evidence suggests that oral XYS alone or in combination with anxiolytic agents is more effective and safer than anxiolytic treatment alone when used for the treatment of AD. However, owing to the limited number and quality of the studies included in this analysis, further high-quality research will be essential to validate these results.
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12

Hong, J. S., J. Tian, Q. F. Han, and Q. Y. Ni. "Quality of life of nasopharyngeal cancer survivors in China." Current Oncology 22, no. 3 (March 18, 2015): 142. http://dx.doi.org/10.3747/co.22.2323.

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Purpose We assessed the quality of life (qol) of nasopharyngeal carcinoma (npc) survivors with a survival time of more than 2 years in Fujian, China, and we analyzed factors influencing qol.Methods We calculated the prevalence of psychological distress and radiotherapy (rt)–induced symptoms in 216 npc survivors who participated in a cross-sectional survey. The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (version 3.0) was used to assess the qol of npc survivors. Multiple linear regression was applied to analyze the factors influencing qol.Results The prevalence rates of rt-induced symptoms and psychological problems were 11.58% (95% ci: 7.21% to 15.58%) for difficulty in swallowing, 17.59% (95% ci: 12.51% to 22.67%) for mouth dryness or sores, 13.89% (95% ci: 9.28% to 18.50%) for nasal dryness or congestion, 18.52% (95% ci: 13.34% to 23.70%) for fatigue, 11.11% (95% ci: 6.92% to 15.30%) for frequent dizziness, 18.06% (95% ci: 12.93% to 23.19%) for decline in hearing, 14.81% (95% ci: 10.07% to 19.55%) for poor sleep quality, 18.52% (95% ci: 13.34% to 23.70%) for worry about disease recurrence, 18.98% (95% ci: 13.75% to 24.21%) for anxiety, and 25.00% (95% ci: 19.23% to 30.77%) for depression. Mean survival times were 4.32 ± 2.63 years in patients with mouth dryness or sores, 4.26 ± 2.90 years in patients with fatigue, and 5.60 ± 2.94 years in patients with a decline in hearing. The mean global qol score was 74.21 (95% ci: 72.22 to 76.20). At a significance level of α = 0.05, the factors influencing qol were age (p = 0.032), education level (p = 0.001), anxiety score (p < 0.001), depression score (p < 0.001), mouth dryness or sores (p < 0.001), fatigue (p = 0.027), and disease stage (p = 0.044).Conclusions The prevalence rates of mouth dryness or sores, fatigue, decline in hearing, depression, and anxiety were high in npc survivors with a survival time of more than 2 years. These rt-induced symptoms and psychological problems can last for many years after rt. The qol of the npc survivors was good. Factors influencing qol were age, education level, anxiety, depression, mouth dryness or sores, fatigue, and disease stage. Our results suggest that during clinical treatment, doctors should minimize the radiation dose to the ears of patients. In addition, our results emphasize the importance of providing oral and ear nursing and psychological care to npc survivors.
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Zhang, Yuanjin, Nan Li, Yiming Zhao, and Dongsheng Fan. "Painful Diabetic Peripheral Neuropathy Study of Chinese OutPatiEnts (PDN-SCOPE): protocol for a multicentre cross-sectional registry study of clinical characteristics and treatment in China." BMJ Open 9, no. 4 (April 2019): e025722. http://dx.doi.org/10.1136/bmjopen-2018-025722.

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IntroductionPainful diabetic peripheral neuropathy (PDN) is a growing public health problem in China. Despite recent progress in treatment, there has been no nationwide study evaluating current medical practices and compliance with treatment guidelines. The primary aims of this study are to investigate the clinical characteristics and treatment practices for PDN and associated anxiety and depression in China.Methods and analysisPainful Diabetic Peripheral Neuropathy Study of Chinese OutPatiEnts is a cross-sectional, multicentre registry study with a target sample size of approximately 1500 people experiencing PDN. People with PDN will be treated according to current guidelines and local practices. The demographics, medical histories, Visual Analogue Scale pain scores, Patient Health Questionnaire-9 results, Generalised Anxiety Disorder-7 scores and therapies will be recorded to evaluate clinical characteristics of PDN and current treatment practices for pain, anxiety and depression.Ethics and disseminationEthical approval has been obtained from the Peking University Third Hospital Medical Science Research Ethics Committee (2018–182).The results of this study will be disseminated through peer-reviewed publications and scientific presentations.Trial registration numberNCT03520608
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Sun, Xiran, Ranming Yang, Qin Zhang, Jing Xiao, Chieh Li, and Lixia Cui. "Cognitive bias modification for interpretation training via smartphones for social anxiety in Chinese undergraduates." Journal of Experimental Psychopathology 10, no. 3 (July 1, 2019): 204380871987527. http://dx.doi.org/10.1177/2043808719875274.

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To address the unmet need for treatment of social anxiety disorder in China, it is timely and relevant to identify more effective, accessible, economic, and easily disseminated interventions. The present study examined the effect of an eight-session program for cognitive bias modification for interpretation (CBM-I). Smartphones were used in the training of reducing interpretation bias and social anxiety of Chinese undergraduates with high social anxiety. In total, 38 participants were randomly assigned to either a CBM-I training group ( n = 19) or a control group ( n = 19). As a result, the CBM-I training group provided more positive interpretations in ambiguous situations and less social anxiety than the control group. Results indicate that CBM-I training via smartphones can effectively promote positive interpretations of ambiguous situations and relieve social anxiety. CBM-I via smartphones may have clinical utility when applied as a multisession intervention of social anxiety for Chinese undergraduates.
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Yin, Wenyuan, Lin Pang, Xiaobin Cao, Jennifer M. McGoogan, Michael Liu, Congbin Zhang, Zhijun Li, Jianhua Li, and Keming Rou. "Factors associated with depression and anxiety among patients attending community-based methadone maintenance treatment in China." Addiction 110 (December 23, 2014): 51–60. http://dx.doi.org/10.1111/add.12780.

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Liu, Fushui, Ting Fang, Fanyuan Zhou, Meimei Zhao, Mei Chen, Jianyu You, Yuli Jin, Jinmei Xie, and Zhongyong Liu. "Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China." Pain Research and Management 2018 (September 25, 2018): 1–9. http://dx.doi.org/10.1155/2018/3259431.

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Background. Due to its high morbidity and prevalence, the potential relationships of depression/anxiety symptoms in neck pain (NP) are not well demonstrated. Objectives. This study aimed to conduct a comprehensive estimation of controlled trials of psychological problems and to test hypotheses concerning whether NP was statistically relative to anxiety/depression symptoms. Methods. Chinese literature databases such as the China National Knowledge Infrastructure (CNKI), VIP Information (VIP), Chinese Biomedicine (CBM), and Wanfang Data (WANFANG) were scientifically searched for reports published until February 5, 2018. Controlled trials incorporating NP patients with anxiety/depression versus healthy people were contained. Two researchers screened each article and extracted data, respectively, and blinded to the findings of each other. Meta-analysis was conducted by the Cochrane Collaboration’s RevMan 5.3 and Stata 14.0 (Stata Corp LP, USA) software. Results. We identified 13 eligible studies involving 2339 patients and 3290 healthy people. Compared with healthy control participants, the findings indicated that depression/anxiety symptoms were more common or severe in NP patients (respectively, SMD = 0.89; 95% CI = (0.58, 1.20); P<0.01 and SMD = 0.92; 95% CI = (0.65, 1.20); and P<0.01), results from the pooled data demonstrated no statistical significance between depression/anxiety symptoms and gender in NP patients (resp., SMD = 0.16; 95% CI = (−0.18, 0.51); P=0.35 and SMD = −0.08; 95% CI = (−0.42, 0.27); and P=0.67), and the combined data of the incidence of depression or anxiety symptoms revealed significant difference between NP patients and healthy persons (resp., RR = 4.81; 95% CI = (3.30, 7.01); P<0.01 and RR = 3.29; 95% CI = (2.16, 5.00); and P<0.01). In addition, we did not find articles that met the inclusion criteria, which compared NP patients with other physical illnesses in terms of anxiety/depression symptoms. Conclusions. This meta-analysis suggests that anxiety/depression symptoms are associated with high morbidity in NP patients. We consider these reports support the viewpoint that nonspecific mechanisms mediate mental disturbances in NP. This study may have clinical value for NP, offering an underlying target for the prevention and treatment of anxiety/depression.
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Sun, Ting, Li Luo, Qin-Qin Tian, Wen-Ju Wang, Qing-Qing Liu, Le Yang, Kun Zhang, Wei Zhang, Ming-Gao Zhao, and Qi Yang. "Anxiolytic Effects of 8-O-Acetyl Shanzhiside Methylester on Acute and Chronic Anxiety via Inflammatory Response Inhibition and Excitatory/Inhibitory Transmission Imbalance." Neurotoxicity Research 38, no. 4 (May 4, 2020): 979–91. http://dx.doi.org/10.1007/s12640-020-00203-2.

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Abstract Anxiety leads to a global decline in quality of life and increase in social burden. However, treatments are limited, because the molecular mechanisms underlying complex emotional disorders are poorly understood. We explored the anxiolytic effects of 8-O-acetyl shanzhiside methylester (8-OaS), an active component in Lamiophlomis rotata (L. rotata; Benth.) or Kudo, a traditional herb that has been shown to be effective in the clinical treatment of chronic pain syndromes in China. Two mouse anxiety models were used: forced swimming stress (FSS)–induced anxiety and complete Freund’s adjuvant (CFA)–induced chronic inflammatory pain. All animal behaviors were analyzed on the elevated plus maze and in the open-field test. 8-OaS significantly ameliorated anxiety-like behaviors in both anxiety models and inhibited the translation enhancement of GluN2A, GluN2B, and PSD95. Moreover, a reduction in GABA receptors disrupted the excitatory/inhibitory (E/I) balance in the basolateral amygdala (BLA), indicated by increased excitatory and decreased inhibitory presynaptic release. 8-OaS also blocked microglia activation and reduced the phosphorylation of p38, c-Jun N-terminal kinase (JNK), NF-κB p65, and tumor necrosis factor alpha (TNF-α) in the BLA of anxiety mice. 8-OaS exhibits obvious anxiolytic effects by regulating the excitatory/inhibitory (E/I) synaptic transmission and attenuating inflammatory responses in the BLA.
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Wang, Long, Jing Zuo, Yudong Wang, Li Feng, Xue Zhang, Jing Han, Dan Li, et al. "The relationships between cancer diagnosis/prognosis awareness and quality of life, anxiety, and depression in Chinese gastroesophageal cancer patients: A cross-correlation analysis." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e24111-e24111. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e24111.

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e24111 Background: Many gastroesophageal cancer patients in China are not made aware of their cancer diagnosis/prognosis. Explorations of the differences in depression, anxiety and quality of life between cancer patients with and without such awareness are rare. The aim of this study was to evaluate the correlation between cancer awareness status and quality of life, anxiety and depression in gastroesophageal cancer patients. Methods: Participants were gastroesophageal cancer patients recruited from a medical center in North China. The degree of awareness of their cancer diagnosis/prognosis was evaluated via interviews. Data were collected using the Self-Rating Anxiety/Depression Scale and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and were analyzed using quantitative methods. Results: The study included 157 gastroesophageal cancer patients: 31 were completely unaware of their cancer diagnosis/prognosis (19.75%); 51 were partly aware (32.48%); and 75 were fully aware (47.78%). Thirty patients (19.11%) experienced anxiety and 35 (22.9%) depression. Unawareness of the real disease status was significantly correlated with worse quality of life (cognitive functioning, social functioning and appetite loss) ( Ps < 0.05) and anxiety ( P = 0.003). Conclusions: More than 50% of gastroesophageal cancer patients were unaware their diagnosis/prognosis completely and were more likely to experience worse quality of life and anxiety. Medical staff and family members should take appropriate measures to make patients aware of their cancer diagnosis/prognosis, as awareness is valuable for improving quality of life and negative emotions, contributing to the successful overall management of gastroesophageal cancer.
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Strisanti, Ida Ayu Suptika. "AKUPUNKTUR TERAPI UNTUK MENURUNKAN LEVEL ANSIETAS PADA WANITA DENGAN WEIGHT LOSS RELATED AMENORRHEA: A PILOT STUDY." Jurnal Riset Kesehatan Nasional 4, no. 1 (June 25, 2020): 60. http://dx.doi.org/10.37294/jrkn.v4i1.227.

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ABSTRAKLatar Belakang: Weight loss related amenorrhea merupakan suatu kondisi amenorea yang disebabkan oleh disfungsi hypothalamus atau disebut juga dengan Functional Hypothalamic Amenorrhea (FHA). Ketika seorang wanita mengalami amenorea dalam jangka waktu yang relatif lama, tentunya kondisi ini akan mempengaruhi psikologis wanita tersebut. Oleh sebab itu, mengkaji kondisi psikis dari wanita yang menderita weight loss related amenorrhea dan membantu menurunkan level ansietasnya juga sangat di perlukan. Pilot study ini dilakukan untuk mengetahui efek dari akupunktur terapi untuk menurunkan level ansietas pada wanita dengan weight loss related amenorrhea.Metode: Sebanyak 15 orang wanita dengan diagnose weight loss related amenorrhea bersedia menjadi partisipan dalam pilot study ini. Seluruh partisipan mendapatkan 20 kali terapi yang dilakukan di Shanghai Research Institute of Acupuncture and Meridian, Shanghai-China. Zung Self-Rating Anxiety Scale (SAS) questionnaire digunakan dalam pilot study ini sebagai alat ukur terhadap level ansietas partisipan. Data yang didapatkan dalam study ini, dianalisa menggunakan paired-sample t-test dengan level signifikansi p≤0.05.Hasil: Terdapat penurunan yang signifikan pada hasil SAS partisipan dalam study ini. Sebelum terapi dilakukan, diperoleh hasil SAS sebesar 46.60±8.58 yang mengindikasikan ansietas sedang. Setelah menjalani 20 kali treatment, hasil SAS mengalami penurunan menjadi 41.80±3.07 (p<0.05), yang menunjukan ansietas dalam rentang normal.Kesimpulan: Hasil ini mengindikasikan bahwa akupunktur dapat dijadikan sebagai salah satu metode pengobatan untuk menurunkan level ansietas yang disebabkan oleh weight loss related amenorrhea.Kata kunci: Akupunktur, SAS, ansietas, weight loss related amenorrheaABSTRACTBackground: Weight loss related amenorrhea is a condition caused by dysfunction of the hypothalamic pituitary ovarian axis due to significant weight loss. Amenorrhea that caused by dysfunction of hypothalamic also known as Functional Hypothalamic Amenorrhea (FHA). When this amenorrhea last for long duration of time, it might involve our psychologist condition. This pilot study was conducted to investigate the effect of acupuncture to reduce anxiety level among women with weight loss related amenorrhea. Methods: Fifteen participants were enrolled in this pilot study. The participants received 20 sessions of acupuncture treatment and all of the treatment sessions was conducted in Shanghai Research Institute of Acupuncture and Meridian, Shanghai-China. Zung Self-Rating Anxiety Scale (SAS) questionnaire was used as a measurement tool to measure the anxiety level among participants. Paired-sample t-test was performed to analyze the data result, with significant p value ≤0.05. Results: Significant changes was found in mean score of SAS before and after treatment. It approximately 46.60 ± 8.58 before treatment and it decrease to 41.80 ± 3.07 after treatment (p<0.05). Conclusion: The result of this pilot study suggest that acupuncture is effective and it can be used as treatment method to reduce anxiety level among participants with weight loss related amenorrhea.Keywords: Acupuncture, SAS, anxiety, weight loss related amenorrhea
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Xiao, Yihui, Wenyuan Li, Juan Zhou, Jie Zheng, Xiaojie Cai, Manyun Guo, Xiang Hao, Zhanyi Zhang, Yan Liu, and Zuyi Yuan. "Impact of depression and/or anxiety on patients with percutaneous coronary interventions after acute coronary syndrome: a protocol for a real-world prospective cohort study." BMJ Open 9, no. 9 (September 2019): e027964. http://dx.doi.org/10.1136/bmjopen-2018-027964.

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IntroductionAcute coronary syndrome (ACS) is one of the leading causes of death. Depression and/or anxiety after ACS is common. Studies from developed countries have reported that the occurrence of anxiety or depression after ACS might increase the risk of cardiovascular events and mortality. However, the results varied, and are limited in developing countries. Therefore, well designed large-scale real-world study is needed to make further clarification. The main objective of this study is to evaluate whether depression or anxiety could affect the prognosis of patients with percutaneous coronary intervention (PCI) post-ACS.Method and analysisThe study is a prospective, multicentre, cohort study, which will be performed at 12 large hospitals in northwest China and led by the First Affiliated Hospital of Xi'an Jiaotong University. A total of 5000 patients with PCI post-ACS will be enrolled and followed up for 2 years. Their depression and anxiety status will be evaluated with the Patient Health Questionnaire-9 or Generalised Anxiety Disorder-7 Assessment scales during the follow-up. A Cox proportional hazard model will be used to determine if depression/anxiety after PCI increase the risk of cardiovascular events. The impact of antidepression or antianxiety treatment on the cardiac prognosis will be explored as well among the patients with ACS who received the treatment after PCI.Ethics and disseminationThis study has been approved by the ethics committee of the First Affiliated Hospital of Xi'an Jiaotong University (approval number: XJTU1AF2016LSL-036). The results will be published in research articles or conference papers.Trial registration numberNCT03057691.
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Xu, Chunsen, Miaomiao Hou, Liangxia Su, Ning Qiu, Fandong Yu, Xinhua Zou, Chunling Wang, Jianwei Wang, and Yongfeng He. "The Effect of Environmental Enrichment on Laboratory Rare Minnows (Gobiocypris rarus): Growth, Physiology, and Behavior." Animals 12, no. 4 (February 18, 2022): 514. http://dx.doi.org/10.3390/ani12040514.

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Environmental enrichment is a method to increase environmental heterogeneity, which may reduce stress and improve animal welfare. Previous studies have shown that environmental enrichment can increase the growth rate, decrease aggressive and anxiety-like behaviors, improve learning ability and agility, and reduce cortisol levels in animals. These effects usually differ between species. Unfortunately, habitat enrichment on laboratory fish is poorly studied and seldom adopted in care guidance. Rare minnows (Gobiocypris rarus) have been cultured as a native laboratory fish in China in barren banks without environmental enrichment since 1990; they have been widely used in studies on ecotoxicology, environmental science, and other topics. The purpose of this study was to investigate the effect of environment enrichment on the growth, physiological status, and anxiety-like behavior of laboratory rare minnows. We observed and analyzed SGR, cortisol levels, DA, DOPAC, 5-HT and 5-HIAA, and anxiety-like behavior indexes after one month of treatment in barren (control) and enrichment tanks. We found that there were no significant differences in SGR, anxiety-like behavior, DA, DOPAC, or 5-HIAA levels between the two treatments. However, higher cortisol and 5-HT levels were observed in the enrichment tanks. This study suggests that rare minnows might be influenced by their living environment, and future related studies should consider their environmental enrichment.
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Bharat, Rakhi, Rinku Jagnade, Gopal Katare, and Sonal Daga. "A Study of anxiety and fear level in dental practitioners from coronavirus and need of clinical practice modification to combat Covid -19." UNIVERSITY JOURNAL OF DENTAL SCIENCES 6, no. 3 (January 12, 2021): 92–97. http://dx.doi.org/10.21276/ujds.2020.6.3.24.

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An outbreak of novel corona virus (COVID-19) in China has influenced several aspects of the life of healthcare professionals, especially dentists, who are actually exposed to a higher risk of getting infected due to close interaction with their patients during treatments. The study was conducted to understand the anxiety and fear level of dental practitioners in getting infected during practice in the current corona virus (COVID-19) situation. In addition, also to evaluate their awareness about various practice modifications needed or required to combat COVID-19 during clinical practice. A cross-sectional study was conducted by an online survey from 3rd Aug to 8th Sept 2020. For the central region, a well-defined survey was planned at Google doc. A total of 239 participants from 16 different states of India had responded. Post scrutiny, completed questionnaires (n = 210) were included in the study. Statistical analysis was performed using SPSS version 25. Chi-Square and tests were applied The fear and anxiety levels of dentists are found as; 69% of participants were afraid getting infected from a patient visiting their clinics. 74.8% were scared while providing treatment to patients. 47.1% felt suggest or think not to do practice until the number of COVID-19 patient cases decreases.54.3% participants felt anxiety and scared while interacting to patients while treatments, 81% have fear to carry the infection from clinic to their home and can get their family infected. 40% were afraid of getting quarantined and 59.5% were concerned about the cost of treatment on the off chance if get Infected. Dental practitioners are in a state of anxiety and fear while treating their patients due to the pandemic impact around the community. A number of dental practitioners have either modified their clinical practice process as per recommended guidelines for emergency treatment only, or closed down clinics for an uncertain period.
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Wang, Qing, Junfeng Jia, Kui Zhang, Zhaohui Zheng, and Huilin Liu. "Investigation and Analysis of Anxiety and Quality of Life among Systemic Lupus Erythematosus Patients in Northwestern China." Healthcare 10, no. 11 (October 31, 2022): 2180. http://dx.doi.org/10.3390/healthcare10112180.

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The aim of this study was to provide targeted psychological support and effective nursing for systemic lupus erythematosus (SLE) patients. SLE is a complex, systemic autoimmune disease characterized by recurrent episodes and the involvement of multiple organs. With improvements in SLE treatment and the corresponding increase in patients’ survival time, the quality of life (QoL) of SLE patients has become an important indicator for evaluating the effectiveness of clinical treatments. To explore the anxiety states and health-related QoL of SLE patients, 106 SLE patients were asked to provide responses for the short-form 36 health survey (SF36), and the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) and Visual Analog Scale(VAS). Additionally, the Systemic Lupus Collaborative Clinics Damage Index (SDI) was analyzed. Data regarding patients’ age, gender, education level, occupation, family income, and duration of disease were collected. Regression analysis was performed to identify factors related to patients’ health-related QoL. For the SF36, the mental components score (MCS), mental health (MH), and bodily pain (BP) occupied dominant positions. Additionally, the MH domain was significantly associated with anxiety in SLE patients. Negative relationships were identified between irregular sleep and the scores for role limitations due to physical problem (RP), vitality (VT), and role limitations due to emotional problem (RE) domains. From the analysis of SLEDAI and SDI scores, anxiety among SLE patients was mainly affected by disease activity and quality of life. This study provides a preliminary understanding of the QoL of SLE patients in western China and highlights the need for the future development of strategies to provide targeted psychological support and effective nursing for SLE patients, in order to improve patients’ self-awareness, mental health, and QoL.
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Yu, Ge, Xi Cheng, and Chenggang Jin. "The Effect of Zao Ren An Shen Capsule on Insomnia among Patients with Anxiety: A Randomized Controlled Trial." Evidence-Based Complementary and Alternative Medicine 2022 (December 29, 2022): 1–8. http://dx.doi.org/10.1155/2022/6520849.

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Background. Zao Ren An Shen capsule (ZRASC) is one of the most widely used Chinese herbal medicine (CHM) in treating insomnia, but its effect on insomnia patients with anxiety remains unclear. We aimed to examine the effect of ZRASC combined with alprazolam in anxiety patients compared with those only with alprazolam prescription. Methods. We conducted a single-blind, parallel-group, randomized trial involving persons from 2 hospitals in China. Participants were randomly assigned in a 1 : 1 ratio to the intervention group, in which the participants were provided with ZRASC and alprazolam, or to the control group, in which the participants were provided with alprazolam. The primary outcomes were insomnia symptoms measured by the insomnia severity index (ISI). The secondary outcomes were anxiety symptoms measured with the Hamilton anxiety rating scale (HAMA). All participants were followed up at 2-week and 4-week after the treatment. The effect was estimated using the mixed-effect models. Results. A total of 334 patients were enrolled in the trial. 167 of them (mean (SD) age, 44.4 (12.8) years; 43.1% female) were assigned to the usual treatment group, while 167 (mean (SD) age, 46.0 (13.4) years; 43.7% female) were assigned to the ZRASC group. From baseline to the 4-weekfollow-up, the mean differences in ISI and HAMA scores between the ZRASC group and the usual care group were −2.542 and −2.563, respectively (both p < 0.001 ). Patients in the ZRASC group were more likely to have remission of insomnia and anxiety than those in the control group at the 4-weekfollow-up, with incidence rate ratios of 265% and 213%, respectively (both p < 0.001 ). Proportions of remission were 74.93% ( p < 0.001 ) for insomnia and 85.80% ( p < 0.001 ) for anxiety at 4-weekfollow-up. Conclusions. This randomized study showed that adjunctive treatment with ZRASC was able to reduce insomnia and anxiety symptoms at the 4-weekfollow-up. Trial Registration. This study was registered in the Chinese Clinical Trial Registry (ChiCTR1800019913).
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Muammar Ihsan, Luh Putu Miyako Mutiara Sari, Tabita Febyola Wijaya, and Desi Mevlana Saputri. "The The Effectiveness of Progressive Muscle Relaxation in Reducing Anxiety and Sleep Disturbances in Hospitalized COVID-19 Patients: A Narrative Review." Physical Therapy Journal of Indonesia 2, no. 2 (December 2, 2021): 36–40. http://dx.doi.org/10.51559/ptji.v2i2.31.

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Introduction: Coronavirus disease (COVID-19) has spread rapidly and massively from China to the rest of the world. Many of the hospitalized COVID-19 patients suffered from psychiatric symptoms such as anxiety and sleep disturbances, besides physical symptoms. Treatment of the psychiatric symptoms commonly used sedative, hypnotic, and anti-anxiety drugs. However, these drugs have some side effects. As an alternative, non-pharmacological intervention is needed. Some previous studies have shown that progressive muscle relaxation (PMR) can improve anxiety levels and sleep quality in other hospitalized patients. Therefore, this study was conducted to determine the effectiveness of PMR in hospitalized COVID-19 patients who experienced anxiety and sleep disturbances. Methods: We conducted a narrative review by searching for studies through PubMed and Google Scholar database with a publication time span from 2020 to 2021. Keywords used in the search: [“anxiety” or “sleep quality” or “sleep disturbances” or “COVID-19” or “patients”] and [“progressive muscle relaxation”]. Results: Based on the search result, we found three related articles: two randomized controlled trials and one observational study. The studies examined the effectiveness of PMR to improve anxiety and sleep quality in hospitalized COVID-19 patients. In the results of the three studies, PMR was effective in improving anxiety symptoms and sleep quality in COVID-19 patients. Conclusion: Considering not least of hospitalized COVID-19 patients who experienced anxiety and sleep disturbances, PMR as a non-pharmacological intervention can be implemented, because it is easy to perform and proven effective in reducing anxiety and sleep disturbances.
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Prina, A. M., C. P. Ferri, M. Guerra, C. Brayne, and M. Prince. "Co-occurrence of anxiety and depression amongst older adults in low- and middle-income countries: findings from the 10/66 study." Psychological Medicine 41, no. 10 (April 5, 2011): 2047–56. http://dx.doi.org/10.1017/s0033291711000444.

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BackgroundThere is relative little information about the prevalence and risk factors of co-morbid anxiety and depression in later life. These disorders are often associated with worse response to treatment than either condition alone, and researching their epidemiology in diverse settings is vital to policy makers. We therefore investigated the co-occurrence of anxiety and depressive syndromes amongst older adults living in developing countries and measured the separate and joint effect of these two disorders on levels of associated disability.MethodThe 10/66 study carried out cross-cultural surveys of all residents aged 65 years or over (n=15021) in 11 sites in seven countries (People's Republic of China, India, Cuba, Dominican Republic, Venezuela, Mexico and Peru). Anxiety was measured by using the Geriatric Mental State Examination and the Automated Geriatric Examination for Computer Assisted Taxonomy diagnostic system. Depression was assessed according to International Classification of Diseases 10th revision (ICD-10) and EURO-D criteria. Disability was measured by using the World Health Organization's Disablement Assessment Scale Version II. Zero-inflated negative binomial regression models were used to investigate the association of common mental disorders and disability.ResultsThe prevalence of co-occurring anxiety and depression (with the exclusion of subthreshold disorders) ranged between 0.9% and 4.2% across sites. Gender, socio-economic status, urbanicity and physical co-morbidities were associated with the different co-morbid states. Having both disorders was linked to higher disability scores than having anxiety or depression alone.ConclusionsGiven the close association of co-morbid anxiety and depression with disability, new policies to improve prevention, recognition and treatment will be needed to adapt to ageing populations and their mental health needs.
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Gao, Yining, Fei Sun, Wenwen Jiang, Yuan Fang, Ling Yue, Xiang Lin, and Xia Li. "Beliefs towards the COVID-19 pandemic among patients with emotional disorders in China." General Psychiatry 33, no. 3 (June 2020): e100231. http://dx.doi.org/10.1136/gpsych-2020-100231.

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BackgroundThe novel coronavirus disease 2019 (COVID-19) pandemic has given rise to fear and panic in the public. Although hospitals in China reduced outpatient visits and restricted inpatient admission to lower the risk of transmission of COVID-19, this has significantly affected patients in need of medical attention, for example, patients with emotional disorders.AimsThis study aimed to compare the beliefs towards COVID-19 among outpatients with emotional disorders (ie, anxiety or depression) with those of family caregivers and the general public and examine factors that shape the beliefs towards COVID-19 among outpatients with emotional disorders.MethodsSurvey data from 570 outpatients with anxiety or depression disorders, 449 family caregivers and 470 general public subjects were collected. Multiple stepwise regression analyses were used to describe participants’ level of concern, prevention attitude and positive expectations towards the COVID-19 outbreak.ResultsAbout 70.9% of outpatients had to postpone their mental health treatment; 43.2% of patients admitted that their mental health was adversely affected by the COVID-19 outbreak—these patients tended to be older, male and less educated. After controlling for age and education level, outpatients with emotional disorders had significantly lower levels of concerns but more negative expectations towards COVID-19, compared with family caregivers and the public. Multivariate linear stepwise regression analysis showed that age, education and the perception of the impact of COVID-19 on one’s existing mental illness were significantly associated with outpatients’ beliefs about the epidemic.ConclusionOutpatients with anxiety or depression disorders were relatively less focused on the COVID-19 outbreak, but the impact of the infection was found to be independently associated with their beliefs towards COVID-19. In addition, outpatients who were older and of low educational levels particularly held more negative beliefs about the epidemic, which may place them at a higher risk for poor mental health.
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Lin, Rongbo, Shen Zhao, Hongyu Zhu, Yan Lei, Xiaofang Wen, Yamei Deng, ShuFang Ruan, et al. "Cognitive dysfunction in patients with cancer pain (CP): A multicenter cross-sectional study from China." Journal of Clinical Oncology 37, no. 31_suppl (November 1, 2019): 81. http://dx.doi.org/10.1200/jco.2019.37.31_suppl.81.

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81 Background: Pain is one of the most common symptoms in cancer patients and often has a negative impact on patients’ functional status and quality of life. Cognitive dysfunction can impact the assessment and treatment of pain. Taking analgesics may worsen the cognitive dysfunction. The study of the prevalence of cognitive dysfunction and the association with analgesics in the CP patients is rare in China. This study aimed to investigate the prevalence of cognitive dysfunction in Chinese CP patients and analyze the related factors. Methods: A total of 220 Chinese CP patients in 9 first-grade hospitals received the following assessment: the functional assessment of cancer therapy-cognitive function (FACT-Cog) and numerical rating scale (NRS), Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7). ANOVA and multiple linear regression analysis were performed to explore the related factors. Results: A total of 220 Chinese CP patients received the assessment: The overall incidence of cognitive dysfunction in CP patients was 33.64%, with an average cognitive function score 105.93±21.39. The total cognitive function score and each dimension were negatively correlated with the pain, depression, and anxiety levels. The analgesics did not affect the cognitive function of CP patients. Sleep and smoking history were two key factors influencing the cognitive function. Conclusions: An effective management of pain, depression, anxiety, sleep, and smoking are recommended to protect the cognitive function of patients under CP stress. It is safe and reliable to regularly use the analgesics for CP patients. Clinical trial information: NCT03641820.
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Wang, Cuiyan, Riyu Pan, Xiaoyang Wan, Yilin Tan, Linkang Xu, Cyrus S. Ho, and Roger C. Ho. "Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China." International Journal of Environmental Research and Public Health 17, no. 5 (March 6, 2020): 1729. http://dx.doi.org/10.3390/ijerph17051729.

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Background: The 2019 coronavirus disease (COVID-19) epidemic is a public health emergency of international concern and poses a challenge to psychological resilience. Research data are needed to develop evidence-driven strategies to reduce adverse psychological impacts and psychiatric symptoms during the epidemic. The aim of this study was to survey the general public in China to better understand their levels of psychological impact, anxiety, depression, and stress during the initial stage of the COVID-19 outbreak. The data will be used for future reference. Methods: From 31 January to 2 February 2020, we conducted an online survey using snowball sampling techniques. The online survey collected information on demographic data, physical symptoms in the past 14 days, contact history with COVID-19, knowledge and concerns about COVID-19, precautionary measures against COVID-19, and additional information required with respect to COVID-19. Psychological impact was assessed by the Impact of Event Scale-Revised (IES-R), and mental health status was assessed by the Depression, Anxiety and Stress Scale (DASS-21). Results: This study included 1210 respondents from 194 cities in China. In total, 53.8% of respondents rated the psychological impact of the outbreak as moderate or severe; 16.5% reported moderate to severe depressive symptoms; 28.8% reported moderate to severe anxiety symptoms; and 8.1% reported moderate to severe stress levels. Most respondents spent 20–24 h per day at home (84.7%); were worried about their family members contracting COVID-19 (75.2%); and were satisfied with the amount of health information available (75.1%). Female gender, student status, specific physical symptoms (e.g., myalgia, dizziness, coryza), and poor self-rated health status were significantly associated with a greater psychological impact of the outbreak and higher levels of stress, anxiety, and depression (p < 0.05). Specific up-to-date and accurate health information (e.g., treatment, local outbreak situation) and particular precautionary measures (e.g., hand hygiene, wearing a mask) were associated with a lower psychological impact of the outbreak and lower levels of stress, anxiety, and depression (p < 0.05). Conclusions: During the initial phase of the COVID-19 outbreak in China, more than half of the respondents rated the psychological impact as moderate-to-severe, and about one-third reported moderate-to-severe anxiety. Our findings identify factors associated with a lower level of psychological impact and better mental health status that can be used to formulate psychological interventions to improve the mental health of vulnerable groups during the COVID-19 epidemic.
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Shi, Shuwei. "Acupuncture for the Treatment of Eating Disorders: A Systematic Review." Lecture Notes in Education Psychology and Public Media 1, no. 1 (December 26, 2021): 294–303. http://dx.doi.org/10.54254/lnep.iceipi.2021225.

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Eating disorders are mental health disorders which involve severe problems with thoughts about food and eating behaviors. Acupuncture, an intangible cultural heritage of China, is well known for its ability to release stress and pain. Previous studies suggest that acupuncture has positive effects on treating eating disorders though its effectiveness remains uncertain. A systematic review which illustrated the effects of acupuncture in comparison of other medications was conducted. This review focuses on ten clinical trials published between 2010 and 2020 in Google Scholar and two Chinese databases (i.e. WANGFANG DATA and ZHIWANG). The results have confirmed that acupuncture plays an important role in treating Anorexia, including improvement in patients' Quality of Life and anxiety relief. Evidence has also confirmed the positive effects of pricking Sifeng acupuncture point on treating Infantile Anorexia. In sum, acupuncture is a promising complementary therapy for treating eating disorders. However, further high-quality randomized controlled trials (RCT) with standardized acupuncture protocols are required for each specific eating disorder to validate the treatment effect.
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XIE, Lin, Xiaoming ZHU, Miao LIU, and Yang LIU. "Effectiveness of Cognitive Behavioral Therapy on Health Outcomes in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis." Journal of Evidence-Based Psychotherapies 20, no. 2 (September 1, 2020): 143–63. http://dx.doi.org/10.24193/jebp.2020.2.17.

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"The incidence of psychological distress (such as anxiety and depression) is high in COPD patients. CBT has been proved to reduce depression and anxiety and enhance quality of life. This meta-analysis evaluated the effectiveness of cognitive behavioral therapy(CBT) on patients with chronic obstructive pulmonary disease(COPD). The following electronic databases were searched from inception to March 2020: PubMed, EMBase, Cochrane Library, Web of Science, Medline, OVID, CINAHL, Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Wangfang Database (WF), PsycARTICLES, VIP database. The Scopus and Google scholar database that we did not use. Randomized controlled trials (RCTs) that compared CBT with routine methods of care in COPD were retrieved in electronic databases. The Cochrane Risk of Bias Tool and Review Manager version 5.3 were used for risk of bias assessment and meta-analysis, respectively. Both data synthesis and descriptive analysis were used for outcome assessment. A total of 10 RCTs involving 1173 patients were included. Data synthesis showed that CBT was statistically significant in improving short- and medium-term depression and treatment compliance. Mediumterm anxiety and quality of life were improved among COPD patients receiving CBT, although no significant effect was found for short-term quality of life and anxiety. Descriptive analysis showed that CBT could reduce dyspnea. No clear evidence supports the effectiveness on improving self-efficacy in COPD patients with the use of CBT (P > 0.05). CBT can be a useful strategy to improve the symptoms of depression, dyspnea and treatment compliance in patients with COPD. It can also improve patients’ quality of life and anxiety to some extent, but there is still lack of strong evidence in improving patients’ self-efficacy."
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Li, Wen, Na Zhao, Xiaona Yan, Xiuying Xu, Siyun Zou, Huan Wang, Yulong Li, et al. "Network Analysis of Depression, Anxiety, Posttraumatic Stress Symptoms, Insomnia, Pain, and Fatigue in Clinically Stable Older Patients With Psychiatric Disorders During the COVID-19 Outbreak." Journal of Geriatric Psychiatry and Neurology 35, no. 2 (March 2022): 196–205. http://dx.doi.org/10.1177/08919887221078559.

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Objectives The Coronavirus Disease 2019 (COVID-19) pandemic has profound negative effects on the mental health of clinically stable older patients with psychiatric disorders. This study examined the influential nodes of psychiatric problems and their associations in this population using network analysis. Methods Clinically stable older patients with psychiatric disorders were consecutively recruited from four major psychiatric hospitals in China from May 22 to July 15, 2020. Depressive and anxiety syndromes (depression and anxiety hereafter), insomnia, posttraumatic stress symptoms (PTSS), pain, and fatigue were measured using the Patient Health Questionnaire, General Anxiety Disorder, Insomnia Severity Index, Posttraumatic Stress Disorder Checklist - Civilian Version, and Numeric Rating Scales for pain and fatigue, respectively. Results A total of 1063 participants were included. The network analysis revealed that depression was the most influential node followed by anxiety as indicated by the centrality index of strength. In contrast, the edge connecting depression and anxiety was the strongest edge, followed by the edge connecting depression and insomnia, and the edge connecting depression and fatigue as indicated by edge-weights. The network structure was invariant by gender based on the network structure invariance test (M = .14, P = .20) and global strength invariance tests (S = .08, P = .30). Conclusions Attention should be paid to depression and its associations with anxiety, insomnia, and fatigue in the screening and treatment of mental health problems in clinically stable older psychiatric patients affected by the COVID-19 pandemic.
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Cui, Ying, Danian Li, Borong Zhou, Yanshan Lin, and Yingchun Zeng. "Mediating role of social support between sleep quality, anxiety and depressive symptoms in Chinese women undergoing in vitro fertilization treatment." SAGE Open Medicine 8 (January 2020): 205031212093016. http://dx.doi.org/10.1177/2050312120930163.

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Introduction: Infertility is a significant health problem, and the prevalence of infertility among women is increasing in developing countries. This study aims to explore whether social support plays a mediating role in the links between exogenous variables, sleep quality, anxiety, and depressive symptoms in Chinese women undergoing in vitro fertilization. Methods: This is a cross-sectional study comprising a sample of Chinese women undergoing in vitro fertilization treatment at a tertiary reproductive medicine center located in South China. Results: The final testing model showed good fit, with normed χ2 = 39.317, p = 0.055, comparative fit index = 0.948, Tucker–Lewis index = 0.902, incremental fit index = 0.951, normed fit index = 0.906, root mean square error of approximation = 0.046). The final path model supported the proposed model: partner relationship, a woman’s age, financial strain, duration of infertility, and cycles of in vitro fertilization were exogenous variables for depressive symptoms, while social support was a significant mediator between sleep quality, anxiety, and depressive symptoms. Conclusion: The empirical support from this study could facilitate the development of appropriate interventions to reduce depressive symptoms, and to promote the mental health of Chinese women undergoing in vitro fertilization treatment.
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Gupta, Vishwa Kumar, Niranjan Mohanty, Amulya Ratna Sahoo, Sujata Choudhury, and Chintamani Nayak. "Web-Based Survey on Depression and Anxiety during COVID-19 Pandemic in View of Homoeopathic Perspective." Homœopathic Links 34, no. 01 (February 8, 2021): 017–25. http://dx.doi.org/10.1055/s-0040-1721058.

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Abstract Background The World Health Organisation (WHO) declared coronavirus disease 2019 (COVID-19) as a global pandemic February 2020 after it emerged from Wuhan city of China and spread to most of the world. The most common psychological symptoms found during the pandemics are fear, anxiety, loss of sleep, depression, suicidal tendency, etc. Aim To collect various psychological symptoms, the people are presenting during this type of situations and their proposed homoeopathic treatment. Methodology A web-based survey was conducted to assess the mental health burden in public during the outbreak of COVID-19 pandemic and also to explore the potential influencing factors. The data of 314 volunteers were collected and assessed. Results It was found that the overall proportion of depression and anxiety was 34.4 and 31.21% respectively. About 23.9% of participants had both depression and anxiety. The proportion of depression and anxiety was more in males and age group of 21 to 30 years. Healthcare providers reported more depression and anxiety as compared with other occupations. Among the influencing factors, regular Yoga practice and adequate sleep of 7 hours in the day had good effects in controlling depression and anxiety. Spending time in social media for more than 3 hours a day regularly was also an influencing factor for more depression and anxiety. It was also found that people who frequently got worried about their own health and of near and dear ones had developed more anxiety. The participants who had taken homoeopathic medicines during last month reported less depressive symptoms in comparison to others. Conclusion Homoeopathy has many remedies which can relieve these psychological symptoms as the principle of homoeopathy is based on individualisation which constitutes the physical as well as the mental sphere.
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Yang, Deling, Xiao Zhang, and Jun Zhang. "EXPLORATION OF LANDSCAPE PAINTING IN THE TREATMENT OF ANXIETY DISORDER IN ART EDUCATION." International Journal of Neuropsychopharmacology 25, Supplement_1 (July 1, 2022): A84—A85. http://dx.doi.org/10.1093/ijnp/pyac032.114.

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Abstract Background Under the epidemic situation, people in trouble are constrained by various conditions, and their spiritual needs are gradually increasing. Art plays an increasingly important role in nurturing the resilience and creativity of life through spiritual transcendence. This paper discusses the viewer's appreciation of landscape painting from the perspective of art education, and uses different schools or representative personal landscape paintings to explore the different psychological reactions produced by the visual communication between the viewer and the works. Subjects and Methods Art therapy is a comprehensive discipline, spanning two disciplines: Art and psychology. It involves spiritual science, anthropology and sociology, so as to nourish human emotion, wisdom and imagination, and bring other psychotherapy effects. As the spiritual messenger of mankind, art cultivates our cultural ideal, exercises our toughness and stores energy for us to deal with difficult situations. Art appreciation can improve people's psychological quality and make people have the ability to stabilize their emotions and have a strong will. In this way, art appreciation can play a good role in psychological healing. At the same time, in the process of painting, we studied the regulating effect of this painting style on the mood of college students. We selected 60 students, including 30 males and 30 females. We used the anxiety scale designed by Kim as the measurement scale, and used Likert scoring method to evaluate the scale. Pearson correlation, standard deviation and statistical significance are combined to illustrate the correlation. T-test of independent samples was used to verify the difference between high anxiety group and low anxiety group. According to the statistical value of anxiety, participants were divided into three groups: low, medium and high anxiety groups. The questionnaire includes two kinds of anxiety, namely debilitating anxiety and promoting anxiety. Through t-test, univariate and multivariate analysis of variance and regression analysis, we investigated the relationship between anxiety and self-efficacy of students of different majors and genders. Results The author believes that promoting the study of landscape painting in art education is conducive to regulating people's body and mind. On the one hand, human beings have a natural intimate relationship with nature. On the other hand, the viewer can feel the difference between landscape painting, landscape painting and landscape documentary, because the painter integrates subjective and objective treatment in the picture and conveys different emotions to the viewer. This paper discusses from the following aspects: convey a quiet and peaceful atmosphere, recall the fleeting time, yearn for the mysterious and ethereal scene, stimulate a sense of excitement and pleasure, reflect on life, and trigger a noble and magnificent psychological response. Conclusion On the basis of exploration, through the analysis of landscape painting, the author finds that landscape painting plays an important role in the psychological rehabilitation of the viewer. Landscape painting combines the function of painting psychology and art, which has a certain impact on mankind, regulates the psychological state of the viewer and eliminates obstacles. The application of painting psychology in art education can help viewers appreciate landscape painting from more angles, explore the expression methods and methods used, as well as the emotion and connotation contained therein. It is relatively easy to enter the viewer's inner world with landscape painting as the theme, which can give people great spiritual comfort. In short, teachers should be fully aware of the important position of students' emotional elements in painting, actively improve the role of teachers in teaching activities, pay special attention to their classroom language and behavior, and change from a single knowledge imparter to a classroom manager, coordinator and collaborator. In the teaching process, we should actively organize teaching activities flexibly according to the psychological characteristics of students, strive to build a relaxed and harmonious classroom atmosphere, create a friendly and mutual aid emotional teacher-student relationship, encourage and guide students, and truly be student-centered. In this way, we can reduce students' anxiety, adjust students' psychology to the best state, and promote the all-round development of students' cognition and psychology. Acknowledgement This dissertation is a phase result of the 2020 Project Library “Academic Enhancement Program” by Yang Deling, Guangzhou Academy of Fine Arts, Project Title: Landscape Painting under the Vision of Imaginative Transformation, Project No. 20XSB24. This achievement is the phased result of the planning fund for the research of Humanities and Social Sciences of the Ministry of Education of China “Research on the normal form of personalized interpretation of wisdom Museum Exhibition”, Project No.21ZX038. Supported by the 2021 Guangdong province graduate education innovation plan project “Guangdong joint postgraduate training demonstration base” (Talent training project of joint postgraduate training demonstration base of teaching practice base of Guangzhou Academy of Fine Arts & Guangzhou Ruifeng Audio Technology Corporation), Project No. 6040121010.
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He, Guihua, and Yuan Gao. "CHINA’S EXPERIENCE IN THE RULE OF LAW AND THE IMPROVEMENT OF PUBLIC EMOTION AND BEHAVIOR IN EPIDEMIC PREVENTION AND CONTROL." International Journal of Neuropsychopharmacology 25, Supplement_1 (July 1, 2022): A62. http://dx.doi.org/10.1093/ijnp/pyac032.085.

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Abstract Background China implements a comprehensive strategy of rule of law. In December 2019, some unexplained cases of pneumonia were found in Wuhan, Hubei Province. Declared the fight against coronavirus disease in 2019. In this struggle, the rule of law should also be used in the prevention and control of coronavirus diseases. And constantly committed to improving public anxiety and behavior. Research Objects and Methods In order to understand how China applies the rule of law in epidemic prevention and control and its benefits, this paper uses the method of literature research to study how China applies the rule of law in epidemic prevention and control before the 2019 coronavirus disease outbreak. There are four epidemic prevention stages from the 2019 coronavirus disease outbreak (December 2019) to November 20211. Articles provided for the study include laws, regulations, government documents, news from national media and other official sources. In order to test the influence of emotional behavior, 60 subjects were used in this study. The stressful life events scale was the adolescent self rating life events check list (ASLEC) compiled by Liu Xianchen. The scale consists of 27 items, and the six dimensions are interpersonal relationship, academic stress, punishment, loss, health adaptation and others. It measures the life events that have brought stress to the subjects in the past six months. The scale adopts Likert 6-point scoring method, and 0 ~ 5 points represent “no occurrence, no influence” to “occurrence and extremely serious influence”. Add the scores of all items. The higher the score, the more stressful life events. Internal consistency of life event scale α The coefficient is 0.876. Pearson correlation, standard deviation and statistical significance were used to illustrate the correlation. Independent sample t-test was used to verify the difference between high anxiety group and low anxiety group. According to the statistical value of anxiety, participants were divided into three groups: low, medium and high anxiety groups. The questionnaire includes two kinds of anxiety, namely debilitating anxiety and promoting anxiety. The relationship between anxiety and self-efficacy of students of different majors and genders was investigated by t-test, univariate, multivariate analysis of variance and regression analysis. Results The research shows that before the outbreak of coronavirus disease in 2019, China's epidemic prevention legal system has laid a solid foundation for combating coronavirus disease in 2019. In the four different stages of epidemic prevention and control, the rule of law lies in the prevention, treatment and control of coronavirus diseases and the punishment of illegal and criminal acts. The political and legal departments also participated in the epidemic prevention and control work together with front-line staff. In addition, the rule of law plays an important role in recovery operations. Public legal services and typical cases guide relevant departments to restore service companies. The public convenience services of the judiciary help people quickly resolve disputes without violating the epidemic prevention and control. In view of the deficiency of epidemic prevention and control, it has improved China's public health legal system and blocked the loopholes in the criminal law of the People's Republic of China (hereinafter referred to as the criminal law). Due to the complexity of coronavirus disease, people were afraid from the beginning. However, the effective application of law and penalty enhances people's confidence in prevention and control. However, there is no public psychological service law in China. The rule of law has supported the decisive achievements of the fight against the novel coronavirus, stabilized social order, and enhanced people's confidence in this fight. Conclusion Before and after the outbreak of coronavirus disease in 2019, the rule of law is very important for epidemic prevention and control. The rule of law not only helps to eliminate the virus, but also pays attention to the recovery action after the epidemic and new problems in epidemic prevention and control. The main work of the rule of law will change with the development of the epidemic. The application of law or penalty can appease people afterwards, but it is more important to establish a legal system of public psychological services. But what will not change is that epidemic prevention and control should follow the road of the rule of law. In short, the government should be fully aware of the importance of people's emotional factors. Actively improve the surrounding environment, enhance their respective roles, pay special attention to their own standardized language and behavior, and shift from single display to multi-dimensional management, coordination and cooperation. In the process of prevention and control, actively present personalized psychological state to patients, flexibly organize epidemic prevention activities, strive to create a relaxed and harmonious rehabilitation atmosphere, create a friendly and mutual emotional treatment relationship, encourage and guide more, and truly achieve people-oriented, so as to reduce anxiety and adjust the public psychology to the best state.
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Boyuan, Zhang, Chen Yang, Cheng Ke, Shen Xueyong, and Liu Sheng. "Efficacy of Acupuncture for Psychological Symptoms Associated with Opioid Addiction: A Systematic Review and Meta-Analysis." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–13. http://dx.doi.org/10.1155/2014/313549.

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This review systematically assessed the clinical evidence for and against acupuncture as a treatment for psychological symptoms associated with opioid addiction. The database was accessed from MEDLINE and China Knowledge Resource Integrated Database. We included all randomized clinical trials published in Chinese and English regardless of their controls. Meta-analysis was performed using the RevMan software, version 5.2. We conducted a literature search of 16 databases from their inception to January 2014. Four studies from Western countries did not report any clinical gains in the treatment of psychological symptoms associated with opioid addiction. 10 of 12 studies from China have reported positive findings regarding the use of acupuncture to treat the psychological symptoms associated with opioid addiction. The methodological quality of the included studies was poor. The meta-analysis indicated that there was a significant difference between the treatment group and the control group for anxiety and depression associated with opioid addiction, although groups did not differ on opioid craving. This review and meta-analysis could not confirm that acupuncture was an effective treatment for psychological symptoms associated with opioid addiction. However, considering the potential of acupuncture demonstrated in the included studies, further rigorous randomized controlled trials with long followup are warranted.
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Wang, Ling, Jin Xian, Mi Sun, Xue Wang, Xiaoming Zang, Xin Zhang, Huijuan Yu, and Qi-Wen Tan. "Acupuncture for emotional symptoms in patients with functional gastrointestinal disorders: A systematic review and meta-analysis." PLOS ONE 17, no. 1 (January 27, 2022): e0263166. http://dx.doi.org/10.1371/journal.pone.0263166.

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Background Patients with functional gastrointestinal disorders (FGIDs) also often have emotional symptoms, such as anxiety and depression. The main drugs used for the treatment of FGIDs mainly target single gastrointestinal symptoms and are not effective in regulating emotional symptoms. Evidence has shown that acupuncture can relieve gastrointestinal symptoms in FGIDs patients, but there is no high-quality evidence to show that acupuncture can relieve psychological symptoms in these patients. Objectives To systematically evaluate the clinical efficacy and safety of acupuncture for emotional symptoms in patients with FGIDs. Methods Randomized controlled trials (RCTs) published from database inception through July 31, 2021, were retrieved from three English-language databases (PubMed, the Cochrane Central Register of Controlled Trials, and Embase) and five Chinese-language databases (the China National Knowledge Infrastructure, Wanfang, VIP, Chinese Biomedical, and TCM Literature Analysis and Retrieval databases). RCTs that compared acupuncture with sham acupuncture and pharmacotherapy were included in this study. The score on the depression or anxiety scale after treatment were considered as primary outcomes. The ‘meta’ package (version 4.19–0) in RStudio 1.1.463 was used to analyse the data. Results A total of 2151 patients from 24 RCTs were included in this study. Compared with sham acupuncture, acupuncture was not significantly better at relieving anxiety (standardized mean difference [SMD] -0.35, 95% CI −1.05 to 0.33) and depression (SMD -0.32, 95% CI −0.71 to 0.07) symptoms. Compared with pharmacotherapy, acupuncture was significantly better at relieving anxiety (SMD -0.64, 95% CI -0.93 to -0.35) and depression (SMD -0.46, 95% CI -0.69 to -0.22) symptoms. Conclusions This meta-analysis found that acupuncture can alleviate emotional symptoms in FGID patients better than pharmacotherapy. However, it is not clear whether this effect is based on the placebo effect, specific effect or nonspecific effect of acupuncture. The evidence should be proven by rigorously designed RCTs in the future. PROSPERO registration number CRD42021271899.
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Jiao, Yue, Xiao Guo, Man Luo, Suxia Li, Aihua Liu, Yufeng Zhao, Bin Zhao, et al. "Effect of Transcutaneous Vagus Nerve Stimulation at Auricular Concha for Insomnia: A Randomized Clinical Trial." Evidence-Based Complementary and Alternative Medicine 2020 (August 7, 2020): 1–7. http://dx.doi.org/10.1155/2020/6049891.

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Insomnia inflicts mental burden and decreases physical productivity and affects life quality. Transcutaneous vagus nerve stimulation (ta-VNS) may be an effective treatment option for insomnia. This study aims to evaluate the effect and safety of ta-VNS and compare it with transcutaneous nonvagus nerve stimulation (tn-VNS). A multicenter, randomized, clinical trial was conducted at 3 hospitals in China enrolling 72 insomnia participants from May 2016 to June 2017. Participants were randomly assigned (1 : 1) to receive 40 sessions of ta-VNS or tn-VNS treatment. 63 participants completed the trial. ta-VNS treatment significantly decreased the Pittsburgh Sleep Quality Index score, Epworth Sleepiness Scale score, Flinders Fatigue Scale score, Hamilton Depression Scale score, and Hamilton Anxiety Scale score over 4 weeks compared with those of the baseline. Moreover, it also significantly increased the 36-item Short-Form Health Survey Questionnaire scores compared with that of the baseline. However, it did not show significant differences compared with tn-VNS in changes of primary and secondary outcomes. The incidence of adverse events was low. ta-VNS significantly relieved insomnia over 4 weeks. Moreover, it also alleviated fatigue and improved participants’ quality of life as well as other concomitant symptoms such as depression and anxiety. This trial is registered at Chinese Clinical Trial Registry (http://www.chictr.org.cn) with the registration number: ChiCTR-TRC-13003519.
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Zheng, Chengwen, Zaoying Li, Haizhen Lu, and Yi Zhou. "Effectiveness of Acupuncture on Urinary Retention: A Meta-Analysis." Evidence-Based Complementary and Alternative Medicine 2021 (September 29, 2021): 1–11. http://dx.doi.org/10.1155/2021/2500282.

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Objectives. This study aimed to evaluate the safety and efficacy of acupuncture in the treatment of urinary retention (UR). Methods. Randomized controlled trials investigating the effectiveness of acupuncture in the treatment of UR were identified by searching seven comprehensive databases (Cochrane Library, PubMed, Embase, China National Knowledge Infrastructure, Wanfang Database, China Science and Technology Journal Database, and Chinese Biomedical Literature Database) prior to September 2020. Data analysis was performed using RevMan, version 5.3, and Stata software, version 14.0. Results. A total of 12 studies with 979 participants were included. A random-effects model was used to conduct a meta-analysis on the acupuncture group and the control group. The results show that acupuncture can effectively promote spontaneous urination and reduce anxiety in patients with poor urination (relative risk: 1.35; 95% confidence interval (CI): 1.19–1.53; P < 0.00001 ). The random-effects model showed significant differences in residual urine volume between the acupuncture group and the control group (MD: −84.79, 95% CI: −135.62 to −33.94; P = 0.001 ). Conclusion. Acupuncture is safe and effective in the treatment of UR. However, since the current level of evidence is limited, high-quality, large-sample, multi-center, clinical randomized controlled trials are needed to further confirm our conclusions in the future.
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Ong, Say How, and Yi Ren Tan. "Internet Addiction in Young People." Annals of the Academy of Medicine, Singapore 43, no. 7 (July 15, 2014): 378–82. http://dx.doi.org/10.47102/annals-acadmedsg.v43n7p378.

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In our technology-savvy population, mental health professionals are seeing an increasing trend of excessive Internet use or Internet addiction. Researchers in China, Taiwan and Korea have done extensive research in the field of Internet addiction. Screening instruments are available to identify the presence of Internet addiction and its extent. Internet addiction is frequently associated with mental illnesses such as anxiety, depression, conduct disorder and attention deficit hyperactivity disorder (ADHD). Treatment modalities include individual and group therapies, cognitive behavioural therapy (CBT), family therapy and psychotropic medications. A significant proportion of Singapore adolescents engaging in excessive Internet use are also diagnosed to have concomitant Internet addiction. Despite the presence of a variety of treatment options, future research in this area is needed to address its growing trend and to minimise its negative psychological and social impact on the individuals and their families. Key words: Aetiology, Pathophysiology, Treatment
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Zhao, Rui, Qing Zhou, Xiao-Wen Wang, Cui-Hua Liu, Mo Wang, Qing Yang, Yi-Hui Zhai, et al. "COVID-19 Outbreak and Management Approach for Families with Children on Long-Term Kidney Replacement Therapy." Clinical Journal of the American Society of Nephrology 15, no. 9 (July 14, 2020): 1259–66. http://dx.doi.org/10.2215/cjn.03630320.

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Background and objectivesDuring the coronavirus disease 2019 outbreak, the treatment of families with children on long-term KRT is challenging. This study was conducted to identify the current difficulties, worries regarding the next 2 months, and mental distress experienced by families with children on long-term KRT during the coronavirus disease 2019 outbreak and to deliver possible management approaches to ensure uninterrupted treatment for children on long-term KRT.Design, setting, participants, & measurementsA multicenter online survey was conducted between February 10 and 15, 2020, among the families with children on long-term KRT from five major pediatric dialysis centers in mainland China. The primary caregivers of children currently on long-term KRT were eligible and included. Demographic information, severe acute respiratory syndrome coronavirus 2 infection status, current difficulties, and worries regarding the next 2 months were surveyed using a self-developed questionnaire. The Patient Health Questionnaire-9 and the General Anxiety Disorder Scale-7 were used to screen for depressive symptoms and anxiety, respectively.ResultsAmong the children in the 220 families included in data analysis, 113 (51%) children were on dialysis, and the other 107 (49%) had kidney transplants. No families reported confirmed or suspected cases of coronavirus disease 2019. Overall, 135 (61%) and 173 (79%) caregivers reported having difficulties now and having worries regarding the next 2 months, respectively. Dialysis supply shortage (dialysis group) and hard to have blood tests (kidney transplantation group) were most commonly reported. A total of 29 (13%) caregivers had depressive symptoms, and 24 (11%) had anxiety. After the survey, we offered online and offline interventions to address their problems. At the time of the submission of this paper, no treatment interruption had been reported.ConclusionsThe coronavirus disease 2019 outbreak has had physical, mental, logistical, and financial effects on families with children on long-term KRT.
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Guo, Ying, Hongyu Zhang, Yufei Xie, Xin Tian, Na Luo, and Yan Zhang. "A Cross-Sectional Survey of National Chinese College Students’ Mental Status during COVID-19 Pandemic: Using a Compiled Stress Response Questionnaire." International Journal of Environmental Research and Public Health 19, no. 19 (September 24, 2022): 12079. http://dx.doi.org/10.3390/ijerph191912079.

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As the coronavirus disease (COVID-19) spread, local governments in China adopted severe lockdown measures to control the pandemic. People were restricted from traveling for leisure, business, education, and medical treatment. Changes were observed in people’s psychological states as a result of COVID-19. This study aimed to construct a Stress Response Questionnaire based on the stress response theory for use with college students, to access their authentic mental health conditions and provide psychological intervention suggestions and countermeasures for the emergency plan formulated by the education department. The questionnaire was used to collect responses from a sample of 16,353 college students from 34 provinces in China. The results showed that anxiety levels varied by sex, current location, and pandemic region, each of which predicted different levels of emotional disturbance. Thus, we highly recommend that the Chinese college administration implement appropriate intervention programs and procedures to help college students maintain their mental health.
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Li, Yajie, and Mun Yee Mimi Tse. "An Online Pain Education Program for Working Adults: Pilot Randomized Controlled Trial." Journal of Medical Internet Research 22, no. 1 (January 14, 2020): e15071. http://dx.doi.org/10.2196/15071.

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Background Pain is a common public health concern, and the pain situation among the general population is serious in mainland China. Working adults commonly experience pain because of long sitting times, a lack of free time, and exercise. A lack of pain-related knowledge is also a significant factor. Educational and therapeutic programs delivered online were used more often in Western countries, and accessible programs in China are limited, especially for pain management. Therefore, we carried out an online pain education program for working adults to self-manage pain. The program was delivered through WeChat, a popular and secure social media with a large population base in China. Objective This study aimed to (1) provide pain-related knowledge and self-relief strategies, (2) help participants reduce pain and improve pain-related emotional well-being, and (3) explore participants’ learning performance and the acceptability of the online pain education program. Methods This was a randomized controlled trial. Chinese adults aged between 16 and 60 years with full-time employment, with pain in the past 6 months, and without any mental illness were recruited using snowball sampling through the internet and were randomly allocated to an experimental group and a control group in 1:1 ratio after the baseline assessment. The 4-week educational program that included basic knowledge of pain, pharmacological and nonpharmacological treatments, and related resources was provided only to the experimental group. Outcomes of pain, depression, anxiety, stress, and pain self-efficacy were measured at baseline (T0), posttreatment (T1), and 1-month follow-up (T2). Participants’ acceptability and satisfaction were explored after completing the educational program. Results In total, 95 eligible participants joined in the program: 47 in the experimental group and 48 in the control group. Neck and shoulder, head, and back were most commonly reported pain sites with high pain scores. Pain intensity and interference of the experimental group were significantly reduced after the educational program. Depression, anxiety, and stress clinically improved and pain self-efficacy improved after the educational program. The difference in depression, anxiety, stress, and pain self-efficacy within a group or between groups was not statistically significant; however, clinical improvements were demonstrated. A significant correlation between dosage of the intervention and pain intensity and depression was demonstrated. After completing the educational program, more than half of the participants showed acceptance of and satisfaction with the program, and they were willing to recommend the program to others. Conclusions Our findings highlight the significant potential of this online education program in the treatment of pain. Trial Registration ClinicalTrials.gov NCT03952910; https://clinicaltrials.gov/ct2/show/NCT03952910
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Kuljancic, D. "Study of mental health of medical staff in a specialized hospital for COVID-19 in Novi Sad." European Psychiatry 65, S1 (June 2022): S541. http://dx.doi.org/10.1192/j.eurpsy.2022.1384.

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Introduction The highly infectious novel coronavirus disease (COVID-19) emerged in Wuhan, China in late 2019 and soon became a global pandemic. COVID-19 is escalating medical staff psychological stress and creating an increasingly heavy professional burden. Fear of transmitting the virus to family, community perception of frontline workers as potential disease carriers, extreme workloads and moral dilemmas add additional stressors. In Novi Sad Clinical Centre of Vojvodina (CCV) for the past 2 years there has been a continuous struggle against the COVID-19 crisis. Both senior specialist doctors and newly hired young doctors, some without work experience, were hired immediately after completing their studies. Objectives To investigate the mental health of clinical first-line medical staff in COVID-19 pandemic. Methods This is a cross-sectional study involving CCV staff who worked in the first line of patient treatment during the COVID-19 pandemic. They were given a self-administered questionnaire which included information on demographic and socio-economic characteristics and the validated Depression, Anxiety, and Stress Scales (DASS-21) and the Impact of Events Scale–Revised (IES-R) instrument. A total of 190 medical workers were involved. Results Sixty-two (32,6%) participants screened positive for anxiety, 38 (20%) for depression, 68 (35,8%) for stress, and 22 (11,5%) for clinical concern of PTSD. The most endangered are young nurses and doctors with less than 6 months of previous work experience. Conclusions In conclusion, our results suggest frontline medical staff involved in treatment of COVID-19 patients should be closely monitored as a high-risk group for depression and anxiety, and given proper training before deployment. Disclosure No significant relationships.
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Yang, Xiaoshi, Carrie Kovarik, Yuke Wang, and Shenshui Yu. "A Multi-Site Cross-Sectional Study of Anxiety Symptoms and the Associated Factors Among Chinese Drug Users Undergoing Compulsory Detoxification Treatment." Frontiers in Public Health 9 (March 11, 2021). http://dx.doi.org/10.3389/fpubh.2021.524068.

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Compulsory drug detoxification treatment (CDT) is currently the major drug rehabilitation modality in China, and drug users often suffer from extraordinary levels of stress during CDT, leading to a high prevalence of anxiety symptoms. This study assesses anxiety symptoms of the drug users undergoing CDT and explores the associated factors. A cross-sectional study with cluster sampling was conducted in three cities in Liaoning Province of Northeast China. Nine hundred CDT drug users were interviewed face-to-face with Chinese questionnaires. Hierarchical multiple regression (HMR) analysis was conducted to explore the factors associated with anxiety symptoms. The prevalence of anxiety symptoms among the CDT drug users was substantially high (33.2%). HMR analysis indicated perceived stress and characteristics of drug use such as types of drugs, were the most important contributors to anxiety symptoms. Optimism (LOT-R) played a protective role in reducing anxiety symptoms in this population. Anxiety symptoms of drug users undergoing CDT were present in a significant proportion of the CDT population. Optimism is a protective factor which could attenuate the detrimental effects of perceived stress on anxiety symptoms and potentially improve treatment outcomes.
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Su, Shanshan, Yuan Wang, Wenhui Jiang, Wenqing Zhao, Rui Gao, Yanru Wu, Jing Tao, et al. "Efficacy of Artificial Intelligence-Assisted Psychotherapy in Patients With Anxiety Disorders: A Prospective, National Multicenter Randomized Controlled Trial Protocol." Frontiers in Psychiatry 12 (January 20, 2022). http://dx.doi.org/10.3389/fpsyt.2021.799917.

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BackgroundAnxiety disorders have the highest prevalence of all psychiatric disorders in China. Medication and psychotherapy are two main treatment approaches for this group of disorders, and when used in combinations are significantly more beneficial than medication alone. The resources are insufficient. The availability of psychotherapy is low due to the limited resources. Artificial intelligence (AI)-assisted psychotherapy offers an opportunity to develop an efficient and standardized psychotherapy model and improve the availability of psychotherapy, which is key to improve the clinical efficacy of anxiety disorder treatments.ObjectivesThe present protocol aims to determine whether medication plus AI-assisted psychotherapy has greater efficacy than medication alone in the treatment of anxiety disorders.MethodsWe will recruit patients in eight hospitals in China. Seven hundred and eight patients with anxiety disorders will be randomly allocated on a 1:1 basis to either medication plus AI-assisted psychotherapy group, or medication alone group. We have built an AI psychotherapy robot named XIAO AN. In this study we will deliver psychotherapy to patients in the medication plus AI-assisted psychotherapy group. Patients will be assessed at baseline and at the end of week 2, 4, 8, and 12. Follow-up assessments will be conducted at 3 and 6 months posttreatment. The primary outcome is change of Hamilton Anxiety Rating Scale (HAMA) score from baseline the end of 12-week treatment. A secondary efficacy outcome will be improvement in treatment at an early stage (score reduction in HAMA ≥25% after 2 weeks of treatment). Other measurements include Hamilton Depression Scale, Clinical Global Impression, Treatment Emergent Symptom Scale, Social Disability Screening Schedule, Insomnia Severity Index and so on. Scales will be assessed by independent raters who are blind to treatment allocation and analyses will be conducted by a statistician who is also blind to treatment allocation.DiscussionThis will be the first multicentered randomized controlled single-blind trial in China to assess the efficacy of medication plus AI-assisted psychotherapy compared with medication alone for anxiety disorders. The study has the potential to address the limitations of the limited availability of psychotherapy, and to augment the efficacy of the treatment of anxiety disorders in China.
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Cao, Penghui, Zhaohua Zhang, Jun Zhong, Shichao Xu, Qiaofang Huang, and Ni Fan. "Effects of treatment status and life quality on anxiety in MMT patients." Substance Abuse Treatment, Prevention, and Policy 16, no. 1 (January 13, 2021). http://dx.doi.org/10.1186/s13011-021-00343-4.

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Abstract Background Anxiety, an important factor that affects the therapeutic effect and preservation rate of methadone maintenance treatment, has a high prevalence among MMT patients. This study aims to investigate the effects of treatment status and life quality on anxiety in MMT patients. Methods One hundred and Seventy-seven methadone maintenance treatment users in Guangzhou, China were evaluated. The socio-demographic, duration and MMT-related characteristics were documented. Anxiety level and quality of life were evaluated by Beck Anxiety inventory (BAI) and the Quality of Life-Drug Addiction (QOL-DA) respectively. The correlation between different factors and BAI score was also analyzed. Results The BAI total score and the QOL-DA score were 7.1±8.2, 163.5±21.4 respectively. 30.5% of the subjects showed mild to severe anxiety. Treatment interruption and QOL-DA score had strong correlations with the score of BAI, with correlation coefficients of 0.17 and − 0.08 respectively. Conclusions Anxiety symptoms were commonly presented in MMT patients. Treatment interruption and quality of life are two major factors affecting anxiety of MMT patients.
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"Study on the Correlation Between Mental Health and Socio-Demographics of Patients in Five Designated Treatment Hospitals in China During the Covid-19 Outbreak: A Cross-Sectional Survey." Journal of Educational & Psychological Research 4, no. 1 (January 5, 2022). http://dx.doi.org/10.33140/jepr.04.01.04.

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The global epidemic of 2019 Novel Coronavirus Diseases (COVID-19) has caused many psychological problems. During the peak period of COVID-19 outbreak in China, COVID-19 patients from 5 designated hospitals with new coronary pneumonia were selected by convenient sampling method. Symptom Checklist 90 (SCL-90) were investigated by either a convenient online questionnaire at: WJX.cn as a data collecting platform or an equivalent paper questionnaire. It showed that the positive detection rate of SCL-90 in the COVID-19 patients was 29.83%. The most common mental health problem was anxiety (28.3%), and the top three prominent mental health problems are depression (9.4%), interpersonal sensitivity (9.4%), paranoia ideation (7.7%). Compared with the Chinese adult norm, there were significant differences in the SCL-90 total score and somatization, depression, anxiety, and phobic anxiety dimension (P<0.05). The main influencing factors of mental health of COVID-19 patients are the number of confirmed cases nationwide, sex, marital status and psychological intervention. The mental state of some groups is relatively low, which leads to depression and anxiety more easily. In particular, the most vulnerable group was found to be unmarried women who have a high occurrence rate of mental health problems. We need to pay particular attention to high risk groups, and support patients with increased susceptibility, which will require timely assessment by mental health care professionals.
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Hua, Wei, Sen Wang, Xi Wang, Ying Shao, Yali Wang, Jiangzhu Ye, Bin Su, et al. "Neuropsychiatric Adverse Events During 12 Months of Treatment With Efavirenz in Treatment-Naïve HIV-Infected Patients in China: A Prospective Cohort Study." Frontiers in Psychiatry 12 (February 24, 2021). http://dx.doi.org/10.3389/fpsyt.2021.579448.

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Background: Efavirenz (EFV) is widely used in antiretroviral therapy (ART), but the incidence and risk factors of neuropsychiatric adverse events (NPAEs) after EFV treatment have rarely been studied in Chinese ART naïve patients.Methods: This prospective cohort study assessed HIV-infected patients initiating antiretroviral treatment with EFV to determine prevalence of and factors associated with NPAEs over a 12-month follow-up period using the Hospital Anxiety and Depression Scale (HADS) and the Pittsburgh Sleep Quality Index (PSQI).Results: A total of 546 patients were enrolled. Prevalence of anxiety, depression, and sleep disturbances at baseline were 30.4, 22.7, and 68.1%, respectively. Six patients discontinued treatment due to drug related NPAEs. Treatment was associated with improvements in HADS-A, HADS-D, and PSQI scores over the 12-month follow-up, and the frequencies of patients with anxiety, depression, and sleep disturbances significantly decreased after 12 months. Abnormal baseline HADS-A, HADS-D, and PSQI scores and other factors, including high school education or lower income, unemployment, divorce, and WHO III/IV stages, were associated with severe neuropsychiatric disorders over the 12 months.Conclusions: These findings suggested EFV discontinuation due to NAPEs was low, and the HADS-A, HADS-D, and PSQI scores after 12 months of EFV treatment were associated with several risk factors. The clinicians should keep in mind and routinely screen for the risk factors associated with neuropsychiatric disorders in HIV-infected patients.
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