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Journal articles on the topic 'Antistress'

Author: Grafiati

Published: 6 September 2023

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1

Adnyana, I. Ketut, Retta Nugrahani, Suwendar Suwendar, and Zulfan Zazuli. "Uji Aktivitas Antistres dan Sedatif Minyak Biji Pala (Myristica fragrans Houtt.) pada Mencit Jantan Galur Swiss Webster." Acta Pharmaceutica Indonesia 37, no. 2 (June 29, 2012): 33–38. http://dx.doi.org/10.5614/api.v37i2.4038.

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Telah diteliti efek antistres minyak biji pala (Myristica fragrans Houtt.) yang diberikan secara oral dan aromaterapi secara inhalasi pada mencit jantan Swiss Webster yang diinduksi stres dengan cara imobilisasi. Efek antistres ditentukan berdasarkan jumlah perpindahan mencit dalam kotak transisi terang-gelap dan lama tidur yang diinduksi dengan tiopental. Mencit yang stres ditandai dengan penurunan bobot badan yang bermakna (p<0,05). Minyak biji pala yang diberikan secara oral dengan dosis 16,90 Î¼L/kg bobot badan dan secara aromaterapi dengan konsentrasi 0,4 g/mL dalam minyak kelapa dengan lama inhalasi dua jam memperpanjang waktu tidur (berturut-turut sebesar 208,29±159,63 menit dan 531,00±265,22 menit) secara bermakna (p<0,05) dibadingkan terhadap kontrol (38,00±7,70 menit). Efek antistres minyak biji pala ditandai dengan peningkatan jumlah perpindahan mencit dalam kotak transisi terang-gelap yang berbeda bermakna bermakna dibandingkan terhadap kontrol (9,71±2,98 kali dan 6,71±3,03 kali secara berurutan, p<0,05).Kata kunci: minyak biji pala, Myristica fragrans Houtt, antistres, sedatif.The antistress effect of nutmeg seed oil (Myristica fragrans Houtt.) given orally and as an aromatherapy through inhalation had been evaluated in stressed-male Swiss Webster mice induced by immobilization. The antistress effect was determined based on total number of crossings of mice in light-dark transition box and sleep duration induced by thiopental. Stressed mice were indicated by significant decreased of mice body weight (p<0.05). Nutmeg oil given orally at 16.90 Î¼L/kg body weight and as aromatherapy at concentration of 0.4 g/mL in virgin coconut oil through inhalation for two hours prolonged sleep duration (208.29±159.63 minutes and 531.00±265.22 minutes respectively) significantly (p<0.05) compared to that of control (38.00±7.70 minutes). The nutmeg oil given as aromatherapy by inhalation for two hours significantly increased total number of crossing of mice in light-dark transition box compared to that of control (9.71±2.98 times and 6.71±3.03 times respectively, p<0.05) indicated the antistress effect.Keywords: nutmeg seed oil, Myristica fragrans Houtt, antistress, sedative.

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2

Mokryk, O. Ya, N. M. Sorokivska, I. S. Sorokivskyi, and N. I. Leschyshyn. "Psychological and Pupillo-Algometrical Monitoring of Dental Patients during Their Antistress Therapy." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 7, no. 5 (November 21, 2022): 187–94. http://dx.doi.org/10.26693/jmbs07.05.187.

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The purpose of the study was to investigate the psychological status and pain sensitivity by the pupillometric method in dental patients during preoperative antistress drug therapy. Materials and methods. In 100 patients, during their initial examination, signs of psychological stress were detected in them in social conditions during the last month before surgical interventions, using the PSM-25 scale of Lemoureux-Tessier-Fillion. The level of anxiety and depressive symptoms were determined using the Hospital Anxiety and Depression Scale. Pain sensitivity in patients was studied by measuring the reaction of the pupil of the eye to the action of an algogenic mechanical factor using the developed proprietary technique of digital pupillometry. Depending on the applied schemes of antistress drug therapy, patients were divided into two clinical groups. The control group included 50 people with different levels of psychological stress. During premedication, they were given Gidazepam for sedation. The main group included 50 patients who were under psychological stress. At the stage of preoperative preparation (for 7 days), they were prescribed a course of antistress therapy: enterally the drug “Antistress” (which contains L-tryptophan) and endonasally – dalargin solution. Results and discussion. Psychological stress acquired by patients in social conditions is a favorable background for the appearance of clinical manifestations of anxiety and depression before the start of operations. The use of Gidazepam by stress-labile dental patients of the control group during premedication made it possible to provide antistressor protection only in 8 cases. These patients had a moderate level of psychological stress. The results of psychological testing and pupillo-algometry confirm the need to use alternative medication schemes of antistressor protection for emotionally labile dental patients during their preparation for planned surgical interventions. In patients of the main group with an average level of psychological stress before surgical interventions, antistressor protection was achieved in 100% of cases. The effectiveness of the applied medicinal scheme was statistically significant in comparison with the standard scheme of treatment of psychoemotional tension used by patients of the control group – χ2 - 15.771 (р<0.001). Preoperative antistress therapy was not sufficiently effective for only 16.7% of patients in the main group with a high level of psychological stress. When comparing the results of stress-protective therapy with those of patients in the control group, statistically significant differences were also found – χ2 - 16.875 (р<0.001). Conclusion. In dental patients who are in a state of chronic psychological stress, psychoemotional tension (reactive anxiety) increases and pain sensitivity increases before the start of planned surgical interventions, which is confirmed by psychological tests and digital pupillo-algometry. One-time use of Gidazepam by stress-sensitive patients during premedication is not effective enough to normalize their psycho-emotional state. Prescribing a course of drug antistress therapy (L-tryptophan and dalargin) to dental patients diagnosed with chronic psychological stress allows to statistically reliably normalize their psychoemotional state and reduce pain sensitivity before the start of surgical interventions

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3

Kandilarov, Ilin K., Hristina I. Zlatanova, Maria T. Georgieva-Kotetarova, Ivanka I. Kostadinova, Mariana N. Katsarova, Stela Z. Dimitrova, Ludmil K. Lukanov, and Ferit Sadakov. "Antidepressant Effect and Recognition Memory Improvement of Two Novel Plant Extract Combinations - Antistress I and Anti-stress II on Rats Subjected to a Model of Mild Chronic Stress." Folia Medica 60, no. 1 (March 1, 2018): 110–16. http://dx.doi.org/10.1515/folmed-2017-0073.

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Abstract Background: Chronic stress is one of the main factors which lead to depression – a psychiatric disorder affecting millions of people and predicted to be the second ranked cause of premature death in 2020. Depression is often associated with cognitive disturbances and memory deficit. Plant based therapy could be effective in the treatment of mild to moderate depression due to its low level of adverse reaction, its good tolerability and compliance. Materials and methods: 72 male Wistar rats, divided in 9 groups were given orally for 8 weeks two combinations of dry plant extracts – Antistress I and Antistress II and five individual dry extracts obtained from Serratula coronata, Hypericum perforatum, Valeriana officinalis, Crataegus monogyna and Melissa officinalis. The animals were exposed to a chronic unpredictable mild stress for 8 weeks. The depression-like symptoms were evaluated with Forced swim test while the assessment of the memory deficit was performed with Novel object recognition test. Results: Antistress II demonstrates antidepressant effect while Antistress I doesn’t improve the depressive-like symptoms. The individual extracts of Hypericum perforatum and Valeriana officinalis also possess antidepressant properties. Antistress II improves the cognition as well as the individual extracts of Hypericum perforatum, Valeriana officinalis and especially Serratula coronata. Dry extract from Serratula tend to have the best effect regarding the recognition memory. The effect of Antistress I on memory deficit is negligible. Conclusions: Antistress II possesses antidepressant effect and improves the recognition memory while Antistress I doesn’t demonstrate any of the above-described effects.

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4

Kandilarov, Ilin, Petya Gardjeva, Maria Georgieva-Kotetarova, Hristina Zlatanova, Natalia Vilmosh, Ivanka Kostadinova, Mariana Katsarova, Kiril Atliev, and Stela Dimitrova. "Effect of Plant Extracts Combinations on TNF-α, IL-6 and IL-10 Levels in Serum of Rats Exposed to Acute and Chronic Stress." Plants 12, no. 17 (August 24, 2023): 3049. http://dx.doi.org/10.3390/plants12173049.

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Oxydative stress, anxiety and depression are associated with changes in cytokine levels. Natural products, including individual and combined plant extracts, have the potential to be used in the treatment of neuropsychiatric disorders. The goal of this study is to investigate the effects of two combined plant extracts, rich in flavonoids, on the levels of the cytokines TNF-α, IL-6, and IL-10 in rats subjected to models of acute cold stress and chronic unpredictable stress. The study utilized common medicinal plants such as Valeriana officinalis, Melissa officinalis, Crataegus monogyna, Hypericum perforatum, and Serratula coronata, which were combined in two unique combinations—Antistress I and Antistress II. The compositions of the used extracts were determined by HPLC methods. Pro- and anti-inflammatory cytokines in rats’ serum were measured with Enzyme-linked immunosorbent assay. The results from the acute stress model revealed that the individual extract of Crataegus monogyna decreased levels of TNF-α, while Serratula coronata, Hypericum perforatum, and Valeriana officinalis effectively reduced IL-6 levels. Both combinations, Antistress I and Antistress II, were effective in reducing TNF-α and IL-6 levels, with Antistress II also increasing IL-10 levels. In the chronic stress model, Hypericum perforatum extract decreased the levels of the pro-inflammatory cytokines TNF-α and IL-6, whereas extracts of Serratula coronata and Valeriana officinalis only reduced TNF-α levels. The two combined extracts, Antistress I and Antistress II, decreased TNF-α and IL-6 levels, while Antistress I also reduced the levels of the anti-inflammatory cytokine IL-10. The combinations of plant extracts used in our experiment have not been previously studied or documented in the available literature. However, based on our own experimental results, we can draw the conclusion that the combinations exhibit a more pronounced effect in reducing cytokine levels compared to the individual plant extracts.

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5

Dortier, Jean-François. "La nature, un antistress." Les Grands Dossiers des Sciences Humaines N° 35, no. 6 (June 1, 2014): 16. http://dx.doi.org/10.3917/gdsh.035.0016.

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6

Jacquemont, Guillaume. "Plantes antistress au bureau." Cerveau & Psycho N° 119, no. 3 (March 20, 2020): 9. http://dx.doi.org/10.3917/cerpsy.119.0009.

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7

Zhigacheva, I. V., L. D. Fatkullina, I. F. Rusina, A. G. Shugaev, I. P. Generozova, S. G. Fattakhov, and A. I. Konovalov. "Antistress properties of melafen." Doklady Biochemistry and Biophysics 414, no. 1 (June 2007): 106–8. http://dx.doi.org/10.1134/s1607672907030040.

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8

Doomra, R., and A. Goyal. "Withania somnifera as an antistress herb." Asian Pacific Journal of Health Sciences 6, no. 3 (September 2019): 16–17. http://dx.doi.org/10.21276/apjhs.2019.6.3.4.

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9

Gupta, Prasoon, Dinesh Kumar Yadav, Kiran Babu Siripurapu, Guatam Palit, and Rakesh Maurya. "Constituents ofOcimum sanctumwith Antistress Activity§." Journal of Natural Products 70, no. 9 (September 2007): 1410–16. http://dx.doi.org/10.1021/np0700164.

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10

Uvnäs-Moberg, Kerstin. "Antistress Pattern Induced by Oxytocin." Physiology 13, no. 1 (February 1998): 22–25. http://dx.doi.org/10.1152/physiologyonline.1998.13.1.22.

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Repeated oxytocin injections cause lowered blood pressure, decreased cortisol levels, increased withdrawal latency, increased release of vagally controlled gastrointestinal hormones, and increased weight gain. Together, these effects form an antistress pattern. Nonnoxious sensory stimuli release oxytocin and induce an effect spectrum similar to the one caused by oxytocin injections.

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11

Sarma, D. N. K., R. L. Khosa, J. P. N. Chansauria, and M. Sahai. "Antistress Activity ofTinospora cordifoliaandCentella asiaticaExtracts." Phytotherapy Research 10, no. 2 (March 1996): 181–83. http://dx.doi.org/10.1002/(sici)1099-1573(199603)10:2<181::aid-ptr804>3.0.co;2-6.

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12

Unno, Keiko, Daisuke Furushima, Yuzuki Nomura, Hiroshi Yamada, Kazuaki Iguchi, Kyoko Taguchi, Toshikazu Suzuki, Makoto Ozeki, and Yoriyuki Nakamura. "Antidepressant Effect of Shaded White Leaf Tea Containing High Levels of Caffeine and Amino Acids." Molecules 25, no. 15 (August 3, 2020): 3550. http://dx.doi.org/10.3390/molecules25153550.

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The young leaves of green tea become lighter in color than usual when protected from sunlight by a shading net for about two weeks while growing. These leaves are called “shaded white leaf tea” or SWLT. In the eluate of SWLT, the amount of amino acids (361 mg/L) was significantly higher than that in regular tea (53.5 mg/L). Since theanine and arginine, the first and second most abundant amino acids in SWLT, have significant antistress effects, we examined the antistress effect of SWLT on humans. SWLT or placebo green tea (3 g) was eluted with room-temperature water (500 mL). Participants consumed the tea for one week prior to pharmacy practice and continued for 10 days in the practice period. The state-trait anxiety inventory, an anxiety questionnaire, tended to be scored lower in the SWLT group than the placebo, but other stress markers showed no differences. The effect of the difference in SWLT components examined with mice showed that aspartic acid and asparagine, which are abundant in SWLT, counteracted the antistress effects of theanine and arginine. Large amounts of caffeine also interfered with SWLT’s antistress effect. Thus, SWLT, which is high in caffeine and amino acids, suppressed depressant behavior in mice.

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13

Geetha, K. M., and V. Murugan. "ANTISTRESS ACTIVITY OF A HERBAL EXTRACT." Acta Horticulturae, no. 786 (March 2008): 99–104. http://dx.doi.org/10.17660/actahortic.2008.786.10.

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14

Tsiakitzis, Karyophyllis C., Eleni A. Rekka, Angeliki P. Kourounakis, and Panos N. Kourounakis. "Novel Compounds Designed as Antistress Agents." Journal of Medicinal Chemistry 52, no. 22 (November 26, 2009): 7315–18. http://dx.doi.org/10.1021/jm901169b.

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15

Red. "Wenn Antistress-Strategien allein nicht reichen." MMW - Fortschritte der Medizin 159, no. 8 (May 2017): 70. http://dx.doi.org/10.1007/s15006-017-9588-3.

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16

RIGA, SORIN, and DAN RIGA. "An Antistress and Antiaging Neurometabolic Therapy." Annals of the New York Academy of Sciences 771, no. 1 Stress (December 1995): 535–50. http://dx.doi.org/10.1111/j.1749-6632.1995.tb44708.x.

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17

Sharma, Ankit, Mohammad Mukim, Rahul Ancheria, and Hrishab Jangid. "The A Research Article on Antistress Activity of Herbal Extract Oil of Piper Methysticum on Wistar Albino." Asian Journal of Pharmaceutical Research and Development 9, no. 1 (February 15, 2021): 117–29. http://dx.doi.org/10.22270/ajprd.v9i1.892.

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The research was carried out to determine the antistress activity of piper methysticum and the animal model used was wistar albino due to it’s worldwide acceptability in researches related to psychology .kava (piper methysticum) root extract was used for abundance of kavlactones hence for the sake of study different percentage of suspensions like 4%, 6%, 8%, 12%, 18%, 30% were prepared and diazepam was selected as standard drug.oecd guideline 423 was followed during acute toxicity studies.no symptoms of acute toxicity was seen during 14 days observational period when given a dose of 2000 mg/kg so on this basis two dose level of 200mg/kg and 400 kg were selected for antistress activity.test model selected for antistress activity were forced swim test, tail suspension test and anoxia stress tolerance test.for respective tests a sharp decline in duration of immobility and increase in anoxia stress tolerance was seen.hence we can conclude that piper methysticum can play a significant role in the field of treating stress after futhur extensive clinical research.

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18

Adkar, Prafulla P., Pranita P. Jadhav, Shirishkumar D. Ambavade, V. H. Bhaskar, and Tushar Shelke. "Adaptogenic Activity of Lyophilized Hydroethanol Extract of Pandanus odoratissimus in Swiss Albino Mice." International Scholarly Research Notices 2014 (October 29, 2014): 1–10. http://dx.doi.org/10.1155/2014/429828.

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Background. The leaves of Pandanus odoratissimus Linn have been widely used in Ayurveda to treat a variety of common and stress related disorders. In the present investigation, hydroethanol extract of leaves of Pandanus odoratissimus Linn (LEPO) were evaluated for antistress activity in normal and stress induced mice. Furthermore, the extract was studied for nootropic (adaptogenic) activity in mice and in vitro antioxidant potential to correlate with its adaptogenic and antistress activity. LEPO (100 and 200 mg/kg p.o) was evaluated against forced swimming endurance stress test, anoxia stress tolerance and immobilization stress and chronic cold resistant stress tests, and biomarkers (serum glucose, Corticosterone, WBC, RBC, and DLC count) to assess the antistress activity in mice. Withania somnifera (WS) (100 mg/kg p.o) was selected as reference standard. The parameters like anoxia stress tolerance time were recorded in anoxia stress and estimation of biochemical marker levels and determination of organs weight were carried out in immobilization stress models. Results. Concomitant treatment with LEPO 200 mg/kg significantly increased in anoxia stress tolerance time. Dose dependent significant reduction in serum glucose, corticosterone, and WBC, RBC, and DLC was observed in immobilisation stress model as compared to stressed group. LEOP 200 mg/kg and WS 100 mg/kg significantly reversed/inhibited the stress induced changes in these parameters. The results from the present study indicate that these values also express that dose dependent significant adaptogenic activity in stressed animals. Conclusion. The present study provides scientific support for the antistress (adaptogenic) and nootropic activities of lyophilized hydroethanol extract of Pandanus odoratissimus Linn and substantiate the traditional claims for the usage of Pandanus in stress induced disorders.

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19

Sumanth, Meera, and SS Mustafa. "Antistress, adoptogenic activity ofSida cordifoliaroots in mice." Indian Journal of Pharmaceutical Sciences 71, no. 3 (2009): 323. http://dx.doi.org/10.4103/0250-474x.56027.

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Arinbasarova, A. Yu, E. N. Biryukova, and A. G. Medentsev. "Antistress Systems of the YeastYarrowia lipolitica(Review)." Прикладная биохимия и микробиология 51, no. 2 (2015): 122–31. http://dx.doi.org/10.7868/s0555109915020026.

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21

Salthun-Lassalle, Bénédicte. "A-t-on trouvé une substance antistress ?" Cerveau & Psycho N° 116, no. 11 (October 20, 2019): 8. http://dx.doi.org/10.3917/cerpsy.116.0008.

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22

Gillman, Mark A., and Issy E. Katzeff. "Antistress Hormonal Responses of Analgesic Nitrous Oxide." International Journal of Neuroscience 49, no. 3-4 (January 1989): 199–202. http://dx.doi.org/10.3109/00207458909084825.

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23

Kumar, Ratan, Harish M. Divekar, Vanita Gupta, and Kaushal K. Srivastava. "Antistress and Adaptogenic Activity of Lecithin Supplementation." Journal of Alternative and Complementary Medicine 8, no. 4 (August 2002): 487–92. http://dx.doi.org/10.1089/107555302760253685.

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24

Lazareva, D. N., G. A. Tolstikov, E. K. Alyokhin, V. V. Pletchov, S. K. Sarmanaev, N. R. Bulatova, A. V. Krinskaya, A. V. Val'dman, and V. P. Krivonogov. "Immune modulating and antistress properties of oxymethacyl." European Journal of Pharmacology 183, no. 3 (July 1990): 914–15. http://dx.doi.org/10.1016/0014-2999(90)92749-9.

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25

Hatta, Takeshi, and Minako Nakamura. "Can antistress music tapes reduce mental stress?" Stress Medicine 7, no. 3 (July 1991): 181–84. http://dx.doi.org/10.1002/smi.2460070309.

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26

Tomkevich, Maria. "Sedative antistress activity of ultra high dilutions of fish skin containing alarm pheromone on hydrobionts in comparison with warm blooded animals." International Journal of High Dilution Research - ISSN 1982-6206 17, no. 2 (July 16, 2021): 26–27. http://dx.doi.org/10.51910/ijhdr.v17i2.930.

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27

Yakhin, O. I., A. A. Lubyanov, Z. F. Kalimullina, I. A. Yakhin, V. A. Vakhitov, A. V. Chemeris, F. R. Gimalov, and R. T. Matniyazov. "Antistress activity of plant growth regulator Epin-extra." Russian Agricultural Sciences 35, no. 3 (June 2009): 163–65. http://dx.doi.org/10.3103/s1068367409030094.

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28

Chauhan, NagendraSingh, Kamal Shah, and PrashantKumar Gupta. "Studies on antistress activity of Curculigo Orchioides gaertn." Biomedical and Biotechnology Research Journal (BBRJ) 5, no. 2 (2021): 145. http://dx.doi.org/10.4103/bbrj.bbrj_12_21.

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29

Miftakhutdinov, A. V., E. R. Sayfulmulukov, and E. A. Nogovitsina. "Efficiency of Antistress Feed Additive in Broiler Production." Russian Agricultural Sciences 47, no. 2 (March 2021): 166–71. http://dx.doi.org/10.3103/s1068367421020130.

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30

Jacquemont, Guillaume. "Une nouvelle technique antistress : écrire sur ses échecs." Cerveau & Psycho N° 100, no. 6 (January 6, 2018): 6–7. http://dx.doi.org/10.3917/cerpsy.100.0006.

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31

Raj, C. G. Darshan, B. K. Sarojini, E. S. Sindhu Priya, M. T. Hassan Khan, C. Srinivas, and P. S. Manjula. "Antistress and antimicrobial studies of biphenyl chalcone derivatives." Journal of Fundamental and Applied Sciences 8, no. 3 (March 14, 2018): 782. http://dx.doi.org/10.4314/jfas.v8i3.7.

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Uvnäs-Moberg, K. "348-ROLE OF OXYTOCIN IN ANTISTRESS AND WELLBEING." Journal of Psychosomatic Research 56, no. 6 (June 2004): 595. http://dx.doi.org/10.1016/j.jpsychores.2004.04.115.

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Dunaevskii, Ya E., T. A. Tsybina, G. A. Belyakova, V. I. Domash, T. P. Sharpio, S. A. Zabreiko, and M. A. Belozerskii. "Proteinase Inhibitors as Antistress Proteins in Higher Plants." Applied Biochemistry and Microbiology 41, no. 4 (July 2005): 344–48. http://dx.doi.org/10.1007/s10438-005-0058-9.

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Ratajczak, Piotr, Krzysztof Kus, Małgorzata Zielińska-Przyjemska, Beata Skórczewska, Tomasz Zaprutko, Dorota Kopciuch, Anna Paczkowska, and Elżbieta Nowakowska. "Antistress and antidepressant properties of dapoxetine and vortioxetine." Acta Neurobiologiae Experimentalis 80, no. 3 (2020): 217–24. http://dx.doi.org/10.21307/ane-2020-020.

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35

Arinbasarova, A. Yu, E. N. Biryukova, and A. G. Medentsev. "Antistress systems of the yeast Yarrowia lipolitica (Review)." Applied Biochemistry and Microbiology 51, no. 2 (March 2015): 135–42. http://dx.doi.org/10.1134/s0003683815020027.

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36

Taur, DJ, SA Nirmal, RY Patil, and MD Kharya. "Antistress and antiallergic effects ofFicus bengalensisbark in asthma." Natural Product Research 21, no. 14 (December 2007): 1266–70. http://dx.doi.org/10.1080/14786410701757330.

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37

Patidar, Govind, and ANIS Shaikh. "Antistress Potential of Glycyrrhizin in Chronic Immobilization Stress." Biomedical & Pharmacology Journal 5, no. 2 (December 30, 2012): 273–83. http://dx.doi.org/10.13005/bpj/355.

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38

Poznyak, V. V. "Effect of complex growth regulating preparations on yield of winter wheat (Тriticum aestivum L.) grown after different precursors." Proceedings of the National Academy of Sciences of Belarus. Agrarian Series 57, no. 1 (February 15, 2019): 63–73. http://dx.doi.org/10.29235/1817-7204-2019-57-1-63-73.

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This is the first time in conditions of Semisavanna of Ukraine when mutual effect of winter wheat precursors and three complex growth-regulating preparations on the growth, development and yield of winter wheat grain has been studied. It has been determined that Antistress, Mars-EL and four amino acid complex preparations can be used for winter wheat growing technology with the aim to increase its yield both during the naked fallow sowing, and after a grain precur- © Позняк В. В., 2019 sor. Greater effect is provided by preparations at winter wheat re-sowing - the yield increase made 0.32-0.81 t/ha. The less significant but stable increase in yield of 0.27-0.59 t/ha is provided by complex growth-regulating preparations during sowing wheat over wheat. Use of the studied complex preparations with a wide range of action throughout the growing season had a positive effect on indicators characterizing growth, development and formation of winter wheat yield. The most effective was the joint use of Antistress and Mars-EL preparations (0.5-0.71 t/ha increase) and all the three drugs together (Antistress + Mars-EL + amino acid complex) when additional 0.59-0.81 t/ha of grain was obtained. Thus, our research has shown that use of new promising growth-regulating agents for winter wheat growing technology makes it possible to implement its genetic potential and increase yield more efficiently, which undoubtedly is of a great importance for agricultural farms specializing in production of this crop.

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Ravishankar, K., G. V. N. Kiranmayi, and Y. Rajendra Prasad. "ISOLATION OF TECOMINE FROM ALKALOID FRACTION, INVESTIGATION OF ADAPTOGENIC AND NEUROPSYCHOPHARMACOLOGICAL EFFECTSOF ETHANOLIC, ETHYL ACETATE AND HEXANE FLOWER EXTRACTS OF TECOMA GAUDICHAUDI." INDIAN DRUGS 55, no. 04 (April 28, 2018): 63–74. http://dx.doi.org/10.53879/id.55.04.11198.

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The present study aims to evaluate antistress and neuropharmacological parameters of ethanolic, ethyl acetate and hexane flower extracts of Tecoma gaudichaudi. Forced swim stress was used to evaluate antistress activity. The 24 h urinary excretion of vanillylmandelic acid (VMA) and ascorbic acid were determined by spectrophotometric methods in all groups under normal and stressed conditions. In the present study, the extracts (200 and 400 mg/kg, p.o.) were investigated for nootropic activity in rats with and without stress. Cook’s pole climbing apparatus measures conditioned avoidance response, elevated plus maze determines transfer latency and staircase test calculates the number of steps climbed and rearings in normal and stress induced rats to assess cognitive-improving activities. Cognition was enhanced by daily administration of Tecoma gaudichaudi extracts at doses of 200 and 400 mg/kg, p.o. in dose dependent manner in normal rats. Tecomine and its derivatives were isolated from alkaloidal fraction.

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Morozova, M., A. Alexeev, G. Rupchev, A. Beniashvili, S. Potanin, T. Lepilkina, and D. Burminskiy. "Unique combination of herbal ingredients for everyday distress in medical workers (short-term pilot study)." European Psychiatry 65, S1 (June 2022): S516. http://dx.doi.org/10.1192/j.eurpsy.2022.1315.

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Introduction Psychological distress is a phenomenon that often occurs not only in patients but in normal subjects under excessive psychological pressure. Health care workers are at particular risk of distress in a pandemic. It negatively affects the quality of life, social and physical functioning and can be a trigger of different diseases. The pharmaceutical drugs can be unnecessary active for healthy subjects. Nutraceuticals may be the adequate choice in this situation. Objectives Assessing the effectiveness of the unique antistress combination of the three herbal ingredients (standardized extracts of passionfruit, melissa and catnip) in medical workers with the signs of psychological distress Methods Twenty-four subjects-medical doctors from 30 to 55 years old (15 women; 9 men) were included into the one-week study. Antistress combination was administered 1 tablet tid. The first part of the State-Trait Anxiety Inventory (STAI “State anxiety”) andor a free self-report were done twice (before and at the end of the study) Results From 24 subjects 19 subjects filled out the STAI, free self-reports were received from 10 subjects (5 people provided information about their condition in two forms). STAI scores showed statistically significant decrease in anxiety at the end of the study. A positive effect the emotional condition and quality of sleep was noted in free self-reports. Adverse effects of nutraceuticals were rare, mild, and transient. No negative impact on quality of working condition was registered. Conclusions The pilot study showed the promising effect of antistress combination in medical workers in specific stressful situation. Disclosure No significant relationships.

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Tseng, Min N., Pei C. Chung, and Shean S. Tzean. "Enhancing the Stress Tolerance and Virulence of an Entomopathogen by Metabolic Engineering of Dihydroxynaphthalene Melanin Biosynthesis Genes." Applied and Environmental Microbiology 77, no. 13 (May 13, 2011): 4508–19. http://dx.doi.org/10.1128/aem.02033-10.

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ABSTRACTEntomopathogenic fungi have been used for biocontrol of insect pests for many decades. However, the efficacy of such fungi in field trials is often inconsistent, mainly due to environmental stresses, such as UV radiation, temperature extremes, and desiccation. To circumvent these hurdles, metabolic engineering of dihydroxynaphthalene (DHN) melanin biosynthetic genes (polyketide synthase, scytalone dehydratase, and 1,3,8-trihydroxynaphthalene reductase genes) cloned fromAlternaria alternatawere transformed into the amelanotic entomopathogenic fungusMetarhizium anisopliaeviaAgrobacterium-mediated transformation. Melanin expression in the transformant ofM. anisopliaewas verified by spectrophotometric methods, liquid chromatography/mass spectrometry (LC/MS), and confocal microscopy. The transformant, especially under stresses, showed notably enhanced antistress capacity and virulence, in terms of germination and survival rate, infectivity, and reduced median time to death (LT50) in killing diamondback moth (Plutella xylostella) larvae compared with the wild type. The possible mechanisms in enhancing the stress tolerance and virulence, and the significance and potential for engineering melanin biosynthesis genes in other biocontrol agents and crops to improve antistress fitness are discussed.

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Gulyaev, Sergey M., and Larisa N. Shantanova. "Antistress action of Fornicium uniflorum extract in chronic stress." Reviews on Clinical Pharmacology and Drug Therapy 19, no. 1 (May 21, 2021): 97–102. http://dx.doi.org/10.17816/rcf19197-102.

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The anti-stress effect of the Fornicium uniflorum extract was studied in Wistar rats in model of chronic unpredictable stress. Stress disorders in rats were determined using methods open field, plus elevated maze, forced swimming test, tail suspension model, sucrose test, as well as changes in the weight indicators of stress target organs. The course administration of F. uniflorum extract to rats under conditions of chronic stress prevented the development of behavioral disorders: the indicators of horizontal, vertical motor activities and mink reflex in the open field were, respectively, 1.5, 4 and 2.5 times higher than those of control rats (without treatment) (p 0.05); the time spent in the open arms of the plus elevated maze and the number of entries into them were respectively 3 and 8.5 times greater than the indices of control rats (p 0.05); the time of immobility of rats in the forced swimming test and the model of hanging by the tail were 2 and 3 times less than in the control; the volume of consumption of sucrose solution in the sucrose test by rats was 1.4 times higher than that of control rats (p 0.05), which indicated the antidepressant activity. In the rats treated with F. uniflorum, no changes in the relative mass of stress target organs were noted, in contrast to the control (p 0.05). Therefore, the course administration of F. uniflorum has an anti-stress and antidepressant effect in chronic unpredictable stress.

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Ali, Hanan, and Mona Attia. "RESPONSE OF SALT STRESSED ROSEMARY PLANTS TO ANTISTRESS AGENTS." Scientific Journal of Flowers and Ornamental Plants 2, no. 3 (December 1, 2015): 249–64. http://dx.doi.org/10.21608/sjfop.2015.5117.

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., T. S. Olugbemi, C. O. Ubosi ., G. N. Akpa ., and W. H. Esuga . "Response of Broilers to Antibiotic and Antistress Dietary Inclusion." Pakistan Journal of Nutrition 3, no. 4 (June 15, 2004): 262–63. http://dx.doi.org/10.3923/pjn.2004.262.263.

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Jahagirdar, Abdul Qayyum F., Shivakumar Hugar, VP Patil, and Anant Khot HM Nanjappaiah. "Screening of Antistress activity of Ficus benghalensis Fruit extract." Research Journal of Pharmacy and Technology 13, no. 1 (2020): 191. http://dx.doi.org/10.5958/0974-360x.2020.00039.6.

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Nanumala, Shravan Kumar, B. Varsha Priyanka, N. Divya, S. Shalini, S. Sanjay Singh, and T. Haripriya. "Evaluation of antistress activity of Cassia auriculata seed extract." Journal of Phytopharmacology 7, no. 2 (April 10, 2018): 207–11. http://dx.doi.org/10.31254/phyto.2018.7218.

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Objective: The present study was designed to investigate the anti-stress activity of Cassia auriculata ethanolic seed extract in mice. Methodology: The anti-stress effect was evaluated by using Elevated plus maze (EPM), Force swimming test (FST) and Tail suspension test (TST). The ECS at a doses (250,500 and 1000 mg/kg p.o.) and standard (diazepam 2 mg/kg i.p and fluoxetine 20 mg/kg i.p) was administered. Results: The extract showed the increased in the number of entries and time spent in open arm in Elevated plus maze and decreased in the immobility time in both Force swimming test and Tail suspension test. Conclusion: The effect of ESC on animal behavior was concordant with a significant regulation of GABA and stress hormones. Therefore, this study was attempted to demonstrate the preventive potential of ECS against stress disorders at in vivo levels

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Morgul, E. V., S. N. Belik, A. R. Morgul, I. F. Gorlov, M. I. Slozhenkina, and O. A. Berezina. "The use of aminoacid additives in antistress neuroprotective diets." IOP Conference Series: Earth and Environmental Science 848, no. 1 (September 1, 2021): 012033. http://dx.doi.org/10.1088/1755-1315/848/1/012033.

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Galani, VarshaJ, NikunjB Patel, and BharatkumarG Patel. "Antistress activity of Argyreia speciosa roots in experimental animals." Journal of Ayurveda and Integrative Medicine 2, no. 3 (2011): 129. http://dx.doi.org/10.4103/0975-9476.85551.

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Calabrese, Francesca, Raffaella Molteni, and Marco A. Riva. "Antistress properties of antidepressant drugs and their clinical implications." Pharmacology & Therapeutics 132, no. 1 (October 2011): 39–56. http://dx.doi.org/10.1016/j.pharmthera.2011.05.007.

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Kwon, Hyuk-Jin, Kyeng-Sub Kim, Su-Kueng Kang, Pil-Sang Park, Ji-Yeon Yu, Ji-Min Lim, Yong-Sik Cho, Yoon-Hee Choi, and Shin-Young Park. "Antistress effect of Gagamsanzointang on rat chronic stress model." Korea Journal of Herbology 27, no. 6 (November 30, 2012): 29–35. http://dx.doi.org/10.6116/kjh.2012.27.6.29.

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