Academic literature on the topic 'Antispasmodic activity'
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Journal articles on the topic "Antispasmodic activity"
Martínez-Pérez, Edith Fabiola, Zaida N. Juárez, Luis R. Hernández, and Horacio Bach. "Natural Antispasmodics: Source, Stereochemical Configuration, and Biological Activity." BioMed Research International 2018 (October 8, 2018): 1–32. http://dx.doi.org/10.1155/2018/3819714.
Full textVentura-Martinez, Rosa, Guadalupe Esther Angeles-Lopez, Maria Eva Gonzalez-Trujano, Omar F. Carrasco, and Myrna Deciga-Campos. "Study of Antispasmodic and Antidiarrheal Activities of Tagetes lucida (Mexican Tarragon) in Experimental Models and Its Mechanism of Action." Evidence-Based Complementary and Alternative Medicine 2020 (October 28, 2020): 1–10. http://dx.doi.org/10.1155/2020/7140642.
Full textCechinel Filho, Valdir, Obdúlio Gomes Miguel, Ricardo José Nunes, João Batista Calixto, and Rosendo Augusto Yunes. "Antispasmodic Activity of Xanthoxyline Derivatives: Structure–Activity Relationships." Journal of Pharmaceutical Sciences 84, no. 4 (April 1995): 473–75. http://dx.doi.org/10.1002/jps.2600840416.
Full textDrozdov, V. N., K. I. Arefev, S. Yu Serebrova, I. A. Komissarenko, E. V. Shikh, and A. K. Starodubtsev. "Role of antispasmodics in the treatment of irritable bowel syndrome." Meditsinskiy sovet = Medical Council, no. 5 (May 13, 2021): 155–64. http://dx.doi.org/10.21518/2079-701x-2021-5-155-164.
Full textRomussi. "Antispasmodic Activity of Semi-Synthetic Secoisopimarane Deriva." Scientia Pharmaceutica 77, no. 1 (2009): 215. http://dx.doi.org/10.3797/scipharm.oephg.21.po-16.
Full textKhalid, S., E. Kalaflla, and O. Mohamed. "The Flavonoids ofSolanostemma argeland their Antispasmodic Activity." Planta Medica 58, S 1 (December 1992): 651. http://dx.doi.org/10.1055/s-2006-961661.
Full textAvramenko, T. V., and A. P. Moschich. "Efficacy and safety assessment of viburcol drug for preparation of uterine cervix for childbirth and prevention of labor anomalies." HEALTH OF WOMAN, no. 7(113) (September 30, 2016): 73–78. http://dx.doi.org/10.15574/hw.2016.113.73.
Full textZoofishan, Zoofishan, Norbert Kúsz, Attila Csorba, Gábor Tóth, Judit Hajagos-Tóth, Anna Kothencz, Róbert Gáspár, and Attila Hunyadi. "Antispasmodic Activity of Prenylated Phenolic Compounds from the Root Bark of Morus nigra." Molecules 24, no. 13 (July 8, 2019): 2497. http://dx.doi.org/10.3390/molecules24132497.
Full textLakshmanan, Baskar, Papiya Mazumder, Dinakar Sasmal, and Swastika Ganguly. "Synthesis, antispasmodic and antidiarrheal activities of some 1-substituted imidazole derivatives." Acta Pharmaceutica 61, no. 2 (June 1, 2011): 227–36. http://dx.doi.org/10.2478/v10007-011-0014-6.
Full textMartin, M., M. Diaz, M. Montero, Pilar Prieto, Luis Roman, and Diego Cortes. "Antispasmodic Activity of Benzylisoquinoline Alkaloids Analogous to Papaverine." Planta Medica 59, no. 01 (February 1993): 63–67. http://dx.doi.org/10.1055/s-2006-959606.
Full textDissertations / Theses on the topic "Antispasmodic activity"
Gouveia, Veloso Carlos Arthur. "Estudo Fitoquimico e atividades biologicas de varronia dardani e varronia leucocephala (Cordiaceae)." Electronic Thesis or Diss., La Rochelle, 2022. http://www.theses.fr/2022LAROS038.
Full textBrazil is a country that presents a vast biodiversity, where we find the Caatinga region, represented by plants of the Cordiaceae family, which are employed by local communities as an alternative for the treatment of some diseases, as is the case with the species Varronia dardani and V. leucocephala, whose infusions are used for the relief of gastric pain, menstrual colic, and arthritis. Therefore, the aim of this work was to contribute to the knowledge about these species, by studying their phytochemical and biological properties. To this end, the plant material was collected in the locations of Serra Branca-PB and Maturéia-PB and submitted to extraction processes. The crude ethanolic extract of V. dardani (CEE-VD) was submitted to the determination of total phenolics and to a quantification of rosmarinic acid, considered one of the chemotaxonomic markers of the Cordiaceae family. A screening was performed with CEE-VD to evaluate its spasmolytic activity in various organs. In addition to this biological activity, the antiproliferative activity of the extracts and fractions of all species was evaluated against human melanoma cells (A2058). Using NMR techniques, the compounds isolated from the study species were identified. The screening concerning the activity in smooth muscle, showed that CEE-VD showed a non-selectiv eactivity in the different tissues and for the different agonists tested, showing highest potency in the uterus of rats. From the ethyl acetate fraction of the CEE-VD it was possible the isolation and identification of five flavonoids, being three aglycones (isosakuranetin, naringenin, and rhamnocitrin) and two glycosylated (astragalin andisoquercitrin), besides rosmarinic acid. Regarding the cytotoxic test, the isopropanolicfraction of the extract of roots from V. dardani proved to be more active, and from this fraction the compound vardanone was isolated, the first hydro anthraquinone reported I nV. dardani species. This compound, was used for a chemo informatics study, where its set of isomers was analyzed for activity in the A2058 cell line and some interactions between amino acid residues were observed, compared to the positive controls dacarbazine and vemurafenib, drugs used in current melanoma therapy. The second most active species in the cytotoxic tests was V. leucocephala, from which it was possible to isolate a saikosaponin, already isolated previously in the species. Thus, the chemical and biological results, obtained in this work, contributed to the knowledge about the genus Varronia, furthermore, the study revealed new possibilities for research on these species involving the search for new secondary metabolites, mainly of the class of quinones
O Brasil é um país que possui uma vasta biodiversidade, onde encontramos a região da Caatinga, representada por vegetais da família Cordiaceae, os quais são empregados pelas comunidades locais como uma alternativa para o tratamento de algumas doenças,como é o caso das espécies Varronia dardani e V. leucocephala, cujas infusões são utilizadas para o alívio das dores gástricas, cólica menstrual e artrite. Sendo assim, buscou-se contribuir para o conhecimento sobre essas espécies, mediante o estudo fitoquímico e biológico das mesmas. Para isso, o material vegetal foi coletado nos municípios de Serra Branca-PB e Maturéia-PB e submetidos a processos de extração. O extrato etanólico bruto de V. dardani (EEB-VD) foi submetido à determinação defenólicos totais e à uma quantificação do ácido rosmarínico, considerado um dos marcadores quimiotaxonômicos da família Cordiaceae. Foi realizada uma triagem com o EEB-VD para avaliar a sua atividade espasmolítica em diversos órgãos. Além dessaatividade biológica, foi avaliada a atividade antiproliferativa dos extratos e frações de todas as espécies frente às células de melanoma humano (A2058). Através de técnicas de RMN foram identificadas as substâncias isoladas das espécies do estudo. A triagem relativa à atividade no músculo liso, mostrou que o EEB-VD apresentou uma atividade não seletiva nos diferentes tecidos e para os diferentes agonistas testados, apresentando maior potência no útero de ratos. Da fração acetato de etila do EEB-VD foi possível o isolamento e identificação de cinco flavonoides, sendo três agliconas (isosakuranetina, naringenina e ramnocitrina) e dois glicosilados (astragalina e isoquercitrina), além do ácido rosmarínico. Com relação ao teste citotóxico, a fração isopropanólica do extrato das raízes de V. dardani se mostrou mais ativa, e desta fração foi isolada a vardanona, primeira hidroantraquinona relatada na espécie V. dardani. O composto VD-R-I, foi utilizado para um estudo de quimioinformática, onde o conjunto de isômeros dessa substância foi analisado quanto à atividade na linhagem celular A2058 e foram observadas algumas interações entre resíduos de aminoácidos, comparando com ocontrole positivo dacarbazina e vemurafenibe, drogas utilizadas na terapia atual do melanoma. A segunda espécie mais ativa nos testes citotóxicos foi a V. leucocephala, de onde foi possível isolar uma saikosaponina, já isolada ateriormente na espécie. Logo, osresultados químicos e biológicos, obtidos nesse trabalho, contribuíram para o conhecimento sobre o gênero Varronia, ainda assim, o estudo revelou novas possibilidades de pesquisas nessas espécies envolvendo a busca de novos metabólitossecundários, principalmente da classe das quinonas
Books on the topic "Antispasmodic activity"
Quenneville, Jennifer J. Herbal treatments with antispasmodic properties: Their effects on seizure activity in rats with chronic limbic epilepsy induced by the lithium pilocarpine model. Sudbury, Ont: Laurentian University, Department of Psychology, 1997.
Find full textBook chapters on the topic "Antispasmodic activity"
Carolina Cardoso-Teixeira, Ana, Klausen Oliveira-Abreu, Levy Gabriel de Freitas Brito, Andrelina Noronha Coelho-de-Souza, and José Henrique Leal-Cardoso. "Effects of Terpenes and Terpenoids of Natural Occurrence in Essential Oils on Vascular Smooth Muscle and on Systemic Blood Pressure: Pharmacological Studies and Perspective of Therapeutic Use." In Terpenes and Terpenoids [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94194.
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