Journal articles on the topic 'Antioxidants'
To see the other types of publications on this topic, follow the link: Antioxidants.
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Antioxidants.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Gonokami, Mio, Yoshimasa Yamamoto, Oraphin Chaikumpollert, Yoshito Ohtake, and Seiichi Kawahara. "ANTIOXIDANTS FOR EPDM SEALS EXPOSED TO CHLORINATED TAP WATER." Rubber Chemistry and Technology 87, no. 1 (March 1, 2014): 1–9. http://dx.doi.org/10.5254/rct.13.87963.
Full textAbstract:
ABSTRACT A suitable antioxidant for a poly(ethylene-co-propylene-co-5-ethylidene-2-norbornene) (EPDM) seal in tap water applications was determined with respect to volatilization and decomposition of the antioxidants. Seals were prepared by mixing EPDM with 1 phr antioxidant and other ingredients followed by vulcanizing the mixture at 433 K for 20 min. The resulting EPDM seals were immersed into chlorinated water to investigate accelerated degradation. The change in antioxidant content was measured by gas chromatography/mass spectroscopy (GC/MS) and high-performance liquid chromatography (HPLC). The weight loss of amine antioxidants during vulcanization was quite low due to their low volatility and decomposition. Antioxidant weight loss during accelerated degradation depended on both the antioxidant's ability to trap radicals and solubility in chlorinated water.
2
Petrescu, Florian Ion Tiberiu, Relly Victoria Virgil Petrescu, and Eleni Mimi Buzea. "New natural antioxidants." Independent Journal of Management & Production 11, no. 3 (June 1, 2020): 967. http://dx.doi.org/10.14807/ijmp.v11i3.938.
Full textAbstract:
Antioxidants are, no doubt, an essential part of an optimal health and even traditional doctors support the importance of an appropriate contribution of antioxidants taken through food. Antioxidants are a category of molecules able to inhibit the oxidation of other molecules. The body distributes various nutrients in the body due to their antioxidant properties and also factory antioxidant enzymes to keep under control the reaction in the chain of free radicals. Some antioxidants are produced by the body, but others don't. In addition, the body's natural ability to produce antioxidants decreases with age. Antioxidants play a significant role for health as it may influence the aging by fighting free radicals. There are antioxidants which can’t be produced in the human body, and to be taken through antioxidant-rich foods, or supplements powerful antioxidant. The paper aims to present some natural sources of oxidants that can be obtained through diet.
3
Fadel, Ophélie, Donatien Gomes Rodrigues, Luc Girard, Pierre Bauduin, Anne Rossignol-Castera, Annabelle L’Hermitte, Jean-Charles Gaillard, and Olivier Diat. "Separation and identification of polar polyphenols in oily formulation using high-performance thin-layer chromatography and mass spectroscopy techniques." OCL 25, no. 5 (August 31, 2018): D506. http://dx.doi.org/10.1051/ocl/2018039.
Full textAbstract:
In cosmetics, there is some interest to solubilized polar antioxidant molecules in oil. This is a matrix that can indeed protect these fragile molecules against oxidation and that makes possible the polar antioxidants transfer through the epidermis in order to be delivered within the dermis. Varying the oil formulation allows the achievement of a high content of antioxidants in a natural vegetable oil using an oleo-eco extraction process. However, it was necessary to characterize this content using quantitative and efficient methods such as High-Performance Thin-Layer Chromatography technique. The aim of this work was to develop a method of antioxidant’s characterization with this technique without a preliminary re-extraction of the antioxidants.
4
Shoker, Roaa M. H., Wasan Hamza Al-Shammery, and S. R. Al-Aidy. "A Review Article: Free Radical and Replacement Synthetic Antioxidant by Natural Antioxidant." Journal for Research in Applied Sciences and Biotechnology 2, no. 2 (May 11, 2023): 206–11. http://dx.doi.org/10.55544/jrasb.2.2.29.
Full textAbstract:
Free radical may be responsible of several pathophysiology disease for threatening human life, and they are produced from endogenous and exogenous sources. Using the balanced amount of nutritious diet lead to a good health, may be neutralizing or scavenging free radicals by antioxidants compounds. daily diet have large number of vitamin A, E and C, carotenoids, polyphenols, etc. as natural antioxidants, the main bases of them are fruits, cereals, vegetables, and beverages. Enzymatic and non-enzymatic antioxidant substances are two different kinds that lessen the reactions of free radicals. In order to protect itself from reactive oxygen species, the human body uses an enzyme antioxidant. The two kinds of non-enzymatic antioxidants are natural antioxidants and synthetic antioxidants. The aim of this review is to knowledge a reasons which causes the free radical and balance them by natural antioxidant constituents, and replacement synthetic antioxidant by natural antioxidant, due to daily diet have large amounts from natural antioxidants, and natural antioxidants more effective than synthetic antioxidants, in additional they occurrence in nature and more inexpensive.
5
Smajić Bećić, Arnela, Ramzija Cvrk, Amela Kusur, Halid Junuzović, and Tijana Brčina. "Comparative analysis of the antioxidant capacity of some natural and synthetic antioxidants added to palm oil." Technologica acta 15, no. 2 (March 2023): 19–23. http://dx.doi.org/10.51558/2232-7568.2022.15.2.19.
Full textAbstract:
Various synthetic and natural antioxidants are used to reduce oxidation and its negative impact on the oil during the food frying process. Considering that some studies show the negative impact of synthetic antioxidants on the health of consumers, natural alternatives are being used more and more. BHA and BHT are synthetic antioxidants that are widely used in the food industryand a large number of natural compounds such as phenols, anthocyanins, flavonoids, vitamins, etc. show antioxidant properties. In this study, the antioxidant capacity of oregano and rosemary essential oil was tested and compared with the antioxidant capacity of BHA and BHT. The antioxidant capacity was evaluated by the removal of DPPH radicals and by iron reduction (FRAP). The results of this study showed that the studied essential oils exhibited antioxidant capacity. These oils have a high antioxidant capacity, however, compared to synthetic antioxidants, they show a significantly lower antioxidant capacity but they can be used as natural antioxidants during food processing. KEYWORDS:antioxidant capacity; essential oils; synthetic antioxidants; lipidoxidation
6
Beaulieu, Michaël, Ines Bischofberger, Isabel Lorenz, Lucie Scheelen, and Klaus Fischer. "Reproducing butterflies do not increase intake of antioxidants when they could benefit from them." Biology Letters 12, no. 2 (February 2016): 20150941. http://dx.doi.org/10.1098/rsbl.2015.0941.
Full textAbstract:
The significance of dietary antioxidants may be limited by the ability of animals to exploit them. However, past studies have focused on the effects of dietary antioxidants after ‘antioxidant forced-feeding’, and have overlooked spontaneous antioxidant intake. Here, we found that reproducing female Bicyclus anynana butterflies had higher antioxidant defences and enhanced fecundity when forced to consume antioxidants (polyphenols). Interestingly, these positive effects were not constant across the oviposition period. When given the choice between food resources with and without antioxidants, reproducing butterflies did not target antioxidants when they could have benefited the most from them. Moreover, they did not consume more antioxidants than non-reproducing butterflies. These results emphasize that, despite potential positive effects of dietary antioxidants, the ability of animals to exploit them is likely to restrict their ecological significance.
7
Abeyrathne, Edirisinghe Dewage Nalaka Sandun, Kichang Nam, Xi Huang, and Dong Uk Ahn. "Plant- and Animal-Based Antioxidants’ Structure, Efficacy, Mechanisms, and Applications: A Review." Antioxidants 11, no. 5 (May 23, 2022): 1025. http://dx.doi.org/10.3390/antiox11051025.
Full textAbstract:
Antioxidants are compounds that normally prevent lipid and protein oxidation. They play a major role in preventing many adverse conditions in the human body, including inflammation and cancer. Synthetic antioxidants are widely used in the food industry to prevent the production of adverse compounds that harm humans. However, plant- and animal-based antioxidants are more appealing to consumers than synthetic antioxidants. Plant-based antioxidants are mainly phenolic compounds, carotenoids, and vitamins, while animal-based antioxidants are mainly whole protein or the peptides of meat, fish, egg, milk, and plant proteins. Plant-based antioxidants mainly consist of aromatic rings, while animal-based antioxidants mainly consist of amino acids. The phenolic compounds and peptides act differently in preventing oxidation and can be used in the food and pharmaceutical industries. Therefore, compared with animal-based antioxidants, plant-based compounds are more practical in the food industry. Even though plant-based antioxidant compounds are good sources of antioxidants, animal-based peptides (individual peptides) cannot be considered antioxidant compounds to add to food. However, they can be considered an ingredient that will enhance the antioxidant capacity. This review mainly compares plant- and animal-based antioxidants’ structure, efficacy, mechanisms, and applications.
8
Sadowska-Bartosz, Izabela, and Grzegorz Bartosz. "Effect of Antioxidants Supplementation on Aging and Longevity." BioMed Research International 2014 (2014): 1–17. http://dx.doi.org/10.1155/2014/404680.
Full textAbstract:
If aging is due to or contributed by free radical reactions, as postulated by the free radical theory of aging, lifespan of organisms should be extended by administration of exogenous antioxidants. This paper reviews data on model organisms concerning the effects of exogenous antioxidants (antioxidant vitamins, lipoic acid, coenzyme Q, melatonin, resveratrol, curcumin, other polyphenols, and synthetic antioxidants including antioxidant nanoparticles) on the lifespan of model organisms. Mechanisms of effects of antioxidants, often due to indirect antioxidant action or to action not related to the antioxidant properties of the compounds administered, are discussed. The legitimacy of antioxidant supplementation in human is considered.
9
Sumandiarsa, I. Ketut, Nurul Hamida, Joko Santoso, and Kustiariyah Tarman. "Antioxidant activities from different parts of Sargassum polycystum thalli through ultrasound-assisted extraction (UAE) method." Omni-Akuatika 18, no. 2 (November 22, 2022): 79. http://dx.doi.org/10.20884/1.oa.2022.18.2.907.
Full textAbstract:
Sargassum polycystum is well known as macroalgae that contain active compounds with great function as antioxidants. The antioxidants content of the seaweed has links closely to phenolic compounds. The study is aimed to determine active compound quality from different thalli parts of S. polycystum extracted by Ultra-sound-assisted extraction (UAE). Fresh samples were prepared into three parts, which are apical, middle, and base thallus. Extraction was carried out by ultrasonication method and using 90% acetone as solvent. Levels of total phenols were analyzed using the Reagent Folin-Ciocalteu. Antioxidant activities were analyzed using DPPH, FRAP, and CUPRAC methods. The highest total phenolic content was found at the apical of the thallus, about 875.64 mg GAE/g. The most excellent DPPH antioxidant activities in S. polycystum were found from the apical part of the thallus with an IC 50 value of 38.49 ppm. The FRAP and CUPRAC antioxidant’s capacity showed the highest in the apical part of the thallus, which was 989.93 mol Fe (II)/g and 555.52 µmol Trolox/g, respectively. The extraction results of different parts of the thallus show highly potent active compounds of alkaloids, steroids, phenols, flavonoids, and potent antioxidants activity.Keywords: antioxidants, phytochemical, ultrasonication, S. polycystum
10
Kamaluddin, Irna Diyana Kartika, Pratiwi Trisda Ramadhani, Irmayanti Haidir Bima, Andi Alamanda Irwan, and Rasfayanah F. Matoo. "Comparative Analysis of Antioxidants in Moringa Leaves and Soursop Leaves." Jurnal Biologi Tropis 24, no. 2 (May 2, 2024): 81–88. http://dx.doi.org/10.29303/jbt.v24i2.6760.
Full textAbstract:
Antioxidants are chemical compounds that can donate one or more electrons to free radicals, so antioxidants function to neutralize free radicals. Antioxidants delay and inhibit cell damage through their properties that can neutralize free radicals. Several studies have reported that M.oleifera has antioxidant activity to various pharmacological effects such as anti-inflammatory and anti-cancer. Moringa oleifera or better known as Moringa is a plant that is widely used by the community to overcome various disease complaints. In addition to Moringa leaves, Soursop leaves (Annona muricata L) also have high antioxidant content in their leaves so that these plants can be divided into synthetic antioxidants and natural antioxidants. The use of synthetic antioxidants is currently decreasing due to consideration of the negative effects on health such as liver damage and can cause carcinogens so that their use is replaced by natural antioxidants. The natural antioxidants in question are compounds found in natural materials such as Moringa leaves and Soursop leaves. The type of research used in this study is experimental research by testing the comparison of antioxidant compound activity between Moringa leaves and Soursop leaves using the DPPH method. Moringa leaves had antioxidant activity of 141.34 ppm, while Soursop leaves had antioxidant activity of 82.39 ppm. There is no significant difference in antioxidant activity between Moringa leaves and Soursop leaves.
11
Buřičová, L., M. Andjelkovic, A. Čermáková, Z. Réblová, O. Jurček, E. Kolehmainen, R. Verhé, and F. Kvasnička. "Antioxidant capacity and antioxidants of strawberry, blackberry, and raspberry leaves." Czech Journal of Food Sciences 29, No. 2 (March 25, 2011): 181–89. http://dx.doi.org/10.17221/300/2010-cjfs.
Full textAbstract:
The total phenolic content (Folin-Ciocalteu method), free radical scavenging ability expressed as DPPH value, ferric reducing antioxidant capacity (FRAP), and oxygen radical absorbance capacity (ORAC) were determined in water extracts of leaves from Rosaceae family plants (Fragaria vesca L., Rubus fructicosus L., and Rubus idaeus L.). The antioxidant capacities of the extracts (in the order of the above mentioned methods) were 73.6–88.9%, 60.1–71.4%, 49.7–78.0% respectively, and 45.3–66.5% of that of green tea water extract. Further, the presence of 15 compounds (gallic acid, rutin, ellagic acid, caffeic acid, p-coumaric acid, quercetin, kaempferol, myricetin, quercetin-3-d-glucoside, ascorbic acid, (+)-catechin, (–)-epicatechin, epicatechingallate, epigallocatechin, procyanidin B1) was studied by HPLC-ECD and their antioxidant capacities were compared to the antioxidant capacity of the extracts. Out of the compounds studied, mostly (+)-catechin, ellagic acid, and (–)-epicatechin participated in the antioxidant capacities of the studied plant leaves water extracts. The antioxidant capacity of leaves infusions (determined by DPPH method) was lower than those of red wines and tea infusions, but comparable to the antioxidant capacities of white wines and fruit beverages.
12
Feng, Pengmian, and Lijing Feng. "Recent Advances on Antioxidant Identification Based on Machine Learning Methods." Current Drug Metabolism 21, no. 10 (December 15, 2020): 804–9. http://dx.doi.org/10.2174/1389200221666200719001449.
Full textAbstract:
Antioxidants are molecules that can prevent damages to cells caused by free radicals. Recent studies also demonstrated that antioxidants play roles in preventing diseases. However, the number of known molecules with antioxidant activity is very small. Therefore, it is necessary to identify antioxidants from various resources. In the past several years, a series of computational methods have been proposed to identify antioxidants. In this review, we briefly summarized recent advances in computationally identifying antioxidants. The challenges and future perspectives for identifying antioxidants were also discussed. We hope this review will provide insights into researches on antioxidant identification.
13
Buescher, E. Stephen, and Sarah M. McIlheran. "Colostral Antioxidants." Journal of Pediatric Gastroenterology and Nutrition 14, no. 1 (January 1992): 47–56. http://dx.doi.org/10.1002/j.1536-4801.1992.tb10490.x.
Full textAbstract:
SummaryHuman colostrum contains several antioxidants which prevent the detection of human polymorpho‐nuclear leukocyte (PMN) respiratory burst products. Using column chromatography to fractionate colostrum, two peaks of antioxidant activity were resolved away from colostral proteins and further characterized. One peak contained both cytochrome c‐reducing activity and H2O2‐depleting activity. This peak had the chromatographic, spectral, and antioxidant characteristics of ascorbate, and by high performance liquid chromatography (HPLC) methods, was shown to contain ascorbate as well as at least four other materials. The antioxidant activity in this peak was totally ascorbate oxidase sensitive and partially uricase sensitive. The other peak contained only H2O2‐depleting activity and had the chromatographic, spectral, and antioxidant characteristics of uric acid. By HPLC, uric acid was the only component in this peak and its antioxidant activity was completely uricase sensitive and ascorbate oxidase resistant. Colostral uric acid levels were measured in eight postpartum women and found to be approximately one‐third of simultaneously determined serum uric acid levels. Colostrum contains at least two separate antioxidants, one of which is ascorbate‐like and the other is uric acid. We speculate that these antioxidants may function in human colostrum as traps for neutrophil‐generated reactive oxygen metabolites.
14
Liu, Jie, Yu-Ting Zhao, Wen-Chien Lu, Ping-Hsiu Huang, Tuzz-Ying Song, and Po-Hsien Li. "Bioactive Compounds in Malanto (Kalimeris indica) Leaves and Their Antioxidant Characteristics." Agriculture 13, no. 1 (January 14, 2023): 211. http://dx.doi.org/10.3390/agriculture13010211.
Full textAbstract:
Currently, there is an increasing trend to replace artificial antioxidants with natural antioxidants. However, certain naturally occurring antioxidants have lower antioxidant activities than artificial antioxidants. Therefore, they will not be as effective in preventing cellular damage. Nevertheless, if they are controlled, natural antioxidants represent a valuable alternative to synthetic antioxidants. With regard to current knowledge, new applications of natural antioxidants in the food industry include food additives, feedstuffs, food packaging materials, and nutraceuticals. The younger leaves of Malan (Kalimeris indica (L.) Sch. Bip.), often referred to as “malanto”, are usually eaten as a vegetable. The findings of this study demonstrated that malanto flavonoids form the active ingredient of the naturally occurring malanto. The malanto extract contains six flavonoids with antioxidant capacity. Malanto flavonoids (0.02% addition) were evaluated for their antioxidant effects and were found to be similar to BHT in inhibiting the peroxidation of sesame, soybean, and sunflower oils. This study aims to provide unique insights into the comprehensive utilization of the flavonoids extracted from malanto.
15
Pan, F. G., E. Q. Yang, J. Y. Xu, Y. F. Lu, C. X. Yang, Y. D. Zhang, S. Li, and B. Q. Liu. "Review on preparation methods, mechanisms and applications for antioxidant peptides in oil." Grasas y Aceites 73, no. 4 (December 15, 2022): e478. http://dx.doi.org/10.3989/gya.0560211.
Full textAbstract:
Natural antioxidants, especially those used in edible oil, are safer compared to chemically synthesized antioxidants. Therefore, research on natural antioxidants has become prevelant. Antioxidant peptides derived from food protein can effectively prevent oil oxidation. Protein hydrolyzation is widely applied for the production of antioxidant peptides in industry, and bioinformatics is employed nowadays to generate the desired peptide sequence. Furthermore, the mechanism of antioxidant peptides in the oil system is still controversial, which limits the further development of antioxidant peptides as food antioxidants. This review introduces the preparation method of antioxidant peptides and their mechanisms as well as applications in the oil. It will help to comprehensively understand the function of antioxidant peptides and promote their development in the oil field.
16
Hidayah, Himyatul, Farhamzah, Surya Amal, and Iis Dahlia. "AKTIVITAS KANDUNGAN DAUN SIRIH (Piper betle L.) SEBAGAI ANTIOKSIDAN : LITERATURE REVIEW ARTICLE." Jurnal Buana Farma 2, no. 3 (September 28, 2022): 47–51. http://dx.doi.org/10.36805/jbf.v2i3.549.
Full textAbstract:
Antioxidants are compounds that can inhibit the oxidation of lipids or other molecules by inhibiting the initiation or propagation of chain oxidation reactions. Exogenous antioxidants consist of natural antioxidants and synthetic antioxidants. Concerns about the side effects of using synthetic antioxidants that can increase carcinogenesis have encouraged the use of natural antioxidants as an alternative source of antioxidants. One source of natural antioxidants can be obtained from plant species that contain antioxidants, namely those from Piper betle L. This literature review article aims to determine the content of Piper betle L. betel leaf as an antioxidant. The literature search process used is Google Scholar, PubMet and Science Direct published in 2011-2021. And the search results found 12 articles with each article stating that Piper betle L. Has antioxidant activity which is included in the category of very strong IC50 values. This is because betel contains quercetin, phenolic compounds, chlorogenic acid, atoxin, eugenol and gallic acid
17
Carsono, Nono, Sefren Geiner Tumilaar, Dikdik Kurnia, Diding Latipudin, and Mieke Hermiawati Satari. "A Review of Bioactive Compounds and Antioxidant Activity Properties of Piper Species." Molecules 27, no. 19 (October 10, 2022): 6774. http://dx.doi.org/10.3390/molecules27196774.
Full textAbstract:
Antioxidants are compounds that are able to inhibit the negative effects that come from free radicals. The phenomenon of imbalanced antioxidant production and the accumulation of free radicals in cells and tissues can cause oxidative stress. Excessive free radicals that enter the body cannot be warded off by endogenous antioxidant compounds so that the required antioxidant compounds can come from the outside, which helps in the performance of endogenous antioxidants. Antioxidants that come from outside consist of synthetic and natural antioxidants; however, synthetic antioxidants are not an option because they have toxic and carcinogenic effects. Therefore, the use of natural ingredients is an alternative method that is needed to create a new natural antioxidant compound. Piper species are being considered as possible medicinal plants for the development of new sources of antioxidants. Several studies have been carried out starting from the extract levels, fractions, and compounds of the Piper species, which showed good antioxidant activity. Currently, some of these plants are being used as ingredients in traditional medicines to treat allergies, toothaches, and coughs. This review examines the distribution, botanical data, pharmacology, especially antioxidant activity, and the compounds contained in five Piper species, namely Piper amalago L., Piper betle L., Piper hispidum Sw., Piper longum L., and Piper umbellatum L.
18
Rani, Alka, Khem Saini, Felix Bast, Sanjeet Mehariya, Shashi Bhatia, Roberto Lavecchia, and Antonio Zuorro. "Microorganisms: A Potential Source of Bioactive Molecules for Antioxidant Applications." Molecules 26, no. 4 (February 20, 2021): 1142. http://dx.doi.org/10.3390/molecules26041142.
Full textAbstract:
Oxidative stress originates from an elevated intracellular level of free oxygen radicals that cause lipid peroxidation, protein denaturation, DNA hydroxylation, and apoptosis, ultimately impairing cell viability. Antioxidants scavenge free radicals and reduce oxidative stress, which further helps to prevent cellular damage. Medicinal plants, fruits, and spices are the primary sources of antioxidants from time immemorial. In contrast to plants, microorganisms can be used as a source of antioxidants with the advantage of fast growth under controlled conditions. Further, microbe-based antioxidants are nontoxic, noncarcinogenic, and biodegradable as compared to synthetic antioxidants. The present review aims to summarize the current state of the research on the antioxidant activity of microorganisms including actinomycetes, bacteria, fungi, protozoa, microalgae, and yeast, which produce a variety of antioxidant compounds, i.e., carotenoids, polyphenols, vitamins, and sterol, etc. Special emphasis is given to the mechanisms and signaling pathways followed by antioxidants to scavenge Reactive Oxygen Species (ROS), especially for those antioxidant compounds that have been scarcely investigated so far.
19
Keramat, Shayan, Hiva Sharebiani, Malay Patel, Bahare Fazeli, and Agata Stanek. "The Potential Role of Antioxidants in the Treatment of Peripheral Arterial Disease: A Systematic Review." Antioxidants 11, no. 11 (October 28, 2022): 2126. http://dx.doi.org/10.3390/antiox11112126.
Full textAbstract:
Peripheral arterial disease (PAD) has a worldwide prevalence and is a significant cause of cardiovascular morbidity and mortality. Due to its high prevalence and higher rates of ischemic cardiovascular and lower-extremity events, its treatment is essential. Increased levels of oxidative stress cause disease. This review aimed to evaluate different studies of antioxidant treatments for PAD patients. A systematic search for relevant studies was performed on the PubMed, SCOPUS, and ScienceDirect databases, and 18 studies fulfilled the inclusion criteria. In total, 16.6% of the studies used natural antioxidants, and 83.3% used synthetic antioxidants. The reviewed studies show that natural antioxidants were completely effective in treating PAD, and synthetic antioxidants showed effective results in only 53% of the studies. A less-than-optimal pro-oxidant–antioxidant balance does not improve the symptoms of PAD. In conclusion, antioxidants in their natural forms are more effective for PAD patients, and ensuring the optimal pro-oxidant–antioxidant balance is an effective method for managing treatment with antioxidants.
20
Islam, Muhammad. "Non-physiological antioxidants: How safe?" International Journal of Medicine 5, no. 1 (January 30, 2017): 41. http://dx.doi.org/10.14419/ijm.v5i1.7064.
Full textAbstract:
Antioxidants of various origins, by these days are one of the known health promotion tools in the world. These are also vastly used as over-the-counter medications. Having a protective capacity, antioxidants have been procured much attention in various fields; these include- dietary consumption, medicinal and cosmetic preparations, food and drinks preparation and preservation, and so on. Antioxidants are more concerned with the medical and pharmaceutical fields, where therapeutic applications are the prime apprehension. Our body has a number of antioxidants called physiological antioxidant systems. Generally, antioxidants are the reducing agents. A failure of balance between the production of oxidative substances and internal or physiological antioxidant molecules asks us to intake external or non-physiological antioxidants. How safe the non-physiological antioxidants? This text sketches theoretically a short scenario on safety and precautions of biologically installation of non-physiological antioxidants. This article is an update of previously published article by EC Orthopaedics 5.2 (2017): 29-31, where the author reserves all rights.
21
Butterfield, D. Allan, and Jeffrey N. Keller. "Antioxidants and antioxidant treatment in disease." Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1822, no. 5 (May 2012): 615. http://dx.doi.org/10.1016/j.bbadis.2012.02.020.
Full text
22
Mamataeva, А. Т., Sh А. Abzhanova, А. N. Aralbaeva, R. S. Utegalieva, G. А. Saginbek, and K. I. Almagambetova. "The use of plants with high antioxidant activity in cooking." Journal of Almaty Technological University, no. 3 (September 24, 2022): 19–25. http://dx.doi.org/10.48184/2304-568x-2022-3-19-25.
Full textAbstract:
The quality of food has a significant impact on human health and longevity. Antioxidants are found in large quantities in herbaceous plants. Therefore, foods with high antioxidant activity can be considered one aspect of their quality. Antioxidants, in turn, are a form of activity that inhibits the free-radical oxidative processes that occur in living organisms. Consumption of foods high in antioxidants helps maintain normal human health. Antioxidants are used as food supplements or in prepared meals. Therefore, this article discusses the preparation of food using herbs with high antioxidant activity, based on which the antioxidant content of the finished food, vitamin E indicators. Especially in terms of antioxidant content, it is contained in higher amounts in sweet mint bread products than in dill.
23
Maslennikov, Pavel, Mikhail Zorin, and Anna Seregina. "Analysis of the bioavailability of tea species." E3S Web of Conferences 291 (2021): 02005. http://dx.doi.org/10.1051/e3sconf/202129102005.
Full textAbstract:
In samples of different tea brands the content of biologically active substances (total water-soluble antioxidants content, ascorbic acid, rutin, polyphenols, anthocyanins) was determined. The water-soluble antioxidant biological availability of the studied tea samples was evaluated. Green Tea with Lemon and Ceylon Baikhovi Black Spiced Tea is characterized by similar levels of antioxidant bioavailability. After the consumption of both beverages, there was a definite increase in the content of antioxidants in saliva of individuals with an initially low content of antioxidants. Amaranth Phytotea antioxidants were characterized by low level of bioavailability. The consumption of this beverage did not change the level of antioxidants in saliva, regardless of their initial content.
24
Wen, Yun-Qi, Chang-Hu Xue, Li-Li Xu, Xiao-Han Wang, Shi-Jie Bi, Qian-Qian Xue, Tao Zhang, et al. "Application of Plackett–Burman Design in Screening of Natural Antioxidants Suitable for Anchovy Oil." Antioxidants 8, no. 12 (December 6, 2019): 627. http://dx.doi.org/10.3390/antiox8120627.
Full textAbstract:
Considering the safety of synthetic antioxidants, more and more natural antioxidants have been developed and utilized in foods. This study aimed to screen out a natural antioxidant combination from many antioxidants, which could significantly affect the oxidation stability of anchovy oil, while Plackett–Burman design (PBD) methodology was employed in this screening. According to the statistical results of this design, sesamol, dihydromyricetin, teapolyphenol, and rosemary acid were four significant parameters on the oxidation stability of anchovy oil. Moreover, dihydromyricetin presented the best antioxidant effect among nine kinds of selected antioxidants when they were used alone in anchovy oil. Meanwhile, a combination including sesamol (0.02%), teapolyphenol (0.02%). and rosemary acid (0.02%) was adopted, and its antioxidant ability was similar to that of tert-butylhydroquinone (TBHQ). Additionally, phytic acid as a synergist was used and combined with sesamol, and the antioxidant ability of this combination was better than that of TBHQ. This study presented a reference for the industrial applications of natural antioxidants and synergists in anchovy oil.
25
Molina López, Antonio, Eleazar Lara Padilla, Heliodoro Moya Amaya, Daniel Rojano Ortega, Antonio Jesús Berral Aguilar, Pedro Estevan Navarro, and Francisco José Berral de la Rosa. "Effect of post-training and post-match antioxidants on oxidative stress and inflammation in professional soccer players (Efecto de los antioxidantes post-entrenamiento y post-partido sobre el estrés oxidativo y la inflamación en jugadores profesionales d." Retos 43 (September 28, 2021): 996–1004. http://dx.doi.org/10.47197/retos.v43i0.90276.
Full textAbstract:
The objective of this study was to determine if the addition of post-activity antioxidants is a useful strategy for improving the specific analytical parameters related to oxidative stress and inflammation. The study was carried out in an Italian Serie A soccer team, between October, 2019 and January, 2020. In October, the measurements were carried out on the players without having taken post-activity antioxidant supplementation. The intervention period corresponded from the end of October to the beginning of January, a period in which post- activity antioxidants were supplemented. The results obtained confirmed that the players who took antioxidants during the intervention period in the form of a mixture of a natural pineapple smoothie with a concentrate of tart cherry, pomegranate, black currant and beet in stick form, significantly improved the parameters associated with oxidative stress, although a significant improvement in the parameters related to inflammation was not observed. The use of antioxidants for a period of seventy days is a post-activity intervention strategy that can be considered effective for improving the reduction of parameters related to the oxidative effect derived from the practice of physical exercise at a professional level in soccer, although more studies are needed to determine the anti-inflammatory effect.
Resumen. El objetivo de este estudio fue determinar si la inclusión de antioxidantes post-actividad es una estrategia útil para mejorar los parámetros analíticos específicos relacionados con el estrés oxidativo y la inflamación. El estudio se llevó a cabo en un equipo de fútbol de la Serie A italiana, entre octubre de 2019 y enero de 2020. En octubre, las mediciones se llevaron a cabo en los jugadores sin haber tomado la suplementación antioxidante post-actividad. El periodo de intervención correspondió desde finales de octubre hasta principios de enero, periodo en el que se suplementaron los antioxidantes post-actividad. Los resultados obtenidos confirmaron que los jugadores que tomaron antioxidantes durante el periodo de intervención en forma de una mezcla de un licuado de piña natural con un concentrado de cereza ácida, granada, grosella negra y remolacha en forma de stick, mejoraron significativamente los parámetros asociados al estrés oxidativo, aunque no se observó una mejora significativa en los parámetros relacionados con la inflamación. El uso de antioxidantes durante un periodo de setenta días es una estrategia de intervención post-actividad que puede considerarse eficaz para mejorar la reducción de los parámetros relacionados con el efecto oxidativo derivado de la práctica de ejercicio físico a nivel profesional en el fútbol, aunque se necesitan más estudios para determinar el efecto antiinflamatorio.
26
Vardanyan, L. R., and S. A. Hayrapetyan. "Antioxidant Properties of Ethyl Acetate Osage Orange Extract (Maclura pomifera)." Herald of the Bauman Moscow State Technical University. Series Natural Sciences, no. 3 (102) (June 2022): 96–109. http://dx.doi.org/10.18698/1812-3368-2022-3-96-109.
Full textAbstract:
The antioxidant properties of ethyl acetate extracts of fruits, leaves and bark of the Osage orange (Maclura pomifera) tree were studied by a kinetic method using the example of a model reaction of cymene oxidation. The extracts exhibit antioxidant properties. Findings of the research show that fresh orange maclura fruits contain the greatest amount of antioxidants. At a temperature of 348 K, the effective content of antioxidant substances is 1.05 · 10--3 mol/(l · mg). The analysis of the effective content of antioxidants in each extract revealed that it decreases when the extract is stored at room (289 K) temperature. Antioxidant activities of antioxidants were determined --- rate constants of InH + RO•2→ ROOH + In•. According to the content of antioxidants, the ethyl acetate extracts are distributed in the following order: fruits > bark > leaves, and according to antioxidant activity --- bark > fruits > leaves. The dependence of the effective content of antioxidants on the measurement temperature was examines. The study shows that the effective content of antioxidants increases, especially in the extracts of dried fruits, leaves and bark of Osage orange, with decreasing temperature. This is due to a decrease in the additional initiation of primary radicals as a result of the autoxidation of easily oxidizing substances contained in the extracts
27
Munteanu, Irina Georgiana, and Constantin Apetrei. "A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity." Antioxidants 11, no. 3 (March 18, 2022): 584. http://dx.doi.org/10.3390/antiox11030584.
Full textAbstract:
Currently, there is growing interest in screening and quantifying antioxidants from biological samples in the quest for natural and effective antioxidants to combat free radical-related pathological complications. Antioxidants play an important role in human health and provide a defense against many diseases. Due to the valuable dietary role of these compounds, the analysis and determination of their amount in food is of particular importance. In recent years, many attempts have been made to provide simple, fast, and economical analytical approaches for the on-site detection and determination of antioxidant activity in food antioxidants. In this regard, electrochemical sensors and biosensors are considered promising tools for antioxidant research due to their high sensitivity, fast response time, and ease of miniaturization; thus, they are used in a variety of fields, including food analysis, drug screening, and toxicity research. Herein, we review the recent advances in sensors and biosensors for the detection of antioxidants, underlying principles, and emphasizing advantages, along with limitations regarding the ability to discriminate between the specific antioxidant or quantifying total antioxidant content. In this work, both direct and indirect methods for antioxidants detecting with electrochemical sensors and biosensors are analyzed in detail. This review aims to prove how electrochemical sensors and biosensors represent reliable alternatives to conventional methods for antioxidant analysis.
28
Okoroama, Casmir E., Prince C. Unekwe, Linda C. Okoroama, Samuel U. Okparaoka, and Godwin C. Akuodor. "Evaluation of the protective role of antioxidants: α-tocopherol, vitamin C, and quercetin, against ibuprofen-induced renal damage in male Wistar rats." International Journal of Basic & Clinical Pharmacology 12, no. 5 (August 25, 2023): 631–39. http://dx.doi.org/10.18203/2319-2003.ijbcp20232557.
Full textAbstract:
Background: Ibuprofen, commonly used in management of pains and inflammatory conditions, has been associated with renal damage. The protective role of antioxidants against Ibuprofen-induced renal damage in wistar rats were investigated in this study. Methods: The study was designed in two parts; first, to induce kidney damage and secondly, to determine protective role of antioxidants against ibuprofen-induced kidney injury. In the first phase, two groups of animals were used; one group treated with 120mg/kg ibuprofen daily for 14 days, while the other served as control and had distilled water. Serum malondialdehyde and kidney parameters were estimated after treatment and kidneys harvested for histology. In the protection study, animals were divided into five groups, with groups 1-4 having three sub-groups treated with 120mg/kg Ibuprofen and graded doses of vitamin E, vitamin C and quercetin respectively, while group five served as control. After 14days, antioxidant enzymes and kidney parameters were estimated, and the kidneys harvested for histology. Results: Showed significant (p<0.05) increase in malondialdehyde, urea, creatinine, and uric-acid levels after ibuprofen administration. Conversely, there was significant (p<0.05) reduction in kidney parameters after co-administration of antioxidants with ibuprofen, with significant increase in antioxidant enzymes. Estimated antioxidant’s percentage protection showed vitamin E gave highest protection on the kidneys against ibuprofen-induced damage amongst others. Histology revealed atrophied glomeruli with widened capsular space, desquamated tubular epithelial cells and infiltrating lymphocytes after ibuprofen administration, but showed normal histo-architecture after co-administration with antioxidants. Conclusion: Antioxidants such as α-tocopherol, vitamin C, quercetin, protected against ibuprofen-induced renal damage in Wistar rats.
29
Delgado-Alfaro, Rogelio A., and Zeferino Gómez-Sandoval. "How Sn(IV) Influences on the Reaction Mechanism of 11, tri-Butyl p-Coumarate and Its tri-Butyl-tin p-Coumarate Considering the Solvent Effect: A DFT Level Study." Computation 11, no. 11 (November 3, 2023): 220. http://dx.doi.org/10.3390/computation11110220.
Full textAbstract:
Antioxidants are molecules that neutralize free radicals. In general, the reaction mechanisms of antioxidants are well known. The main reaction mechanisms of antioxidants are electron transfer (ET), hydrogen transfer (HT), and radical adduction formation (RAF). The study of these mechanisms is helpful in understanding how antioxidants control high free radical levels in the cell. There are many studies focused on determining the main mechanism of an antioxidant to neutralize a wide spectrum of radicals, mainly reactive oxygen species (ROS)-type radicals. Most of these antioxidants are polyphenol-type compounds. Some esters, amides, and metal antioxidants have shown antioxidant activity, but there are few experimental and theoretical studies about the antioxidant reaction mechanism of these compounds. In this work, we show the reaction mechanism proposed for two esters, 11, tri-butyl p-coumarate and its tri-butyl-tin p-coumarate counterpart, using Sn(IV). We show how Sn(IV) increases the electron transfer in polar media and the H transfer in non-polar media. Even though the nature of esters could be polar or non-polar compounds, the antioxidant activity is good for the Sn(IV)-p-coumarate complex in non-polar media.
30
Al-Mehdawe, Mohammed S., and J. E. Stuckey. "Rubber-Bound Antioxidants. I. Amine Antioxidants Bound to Polychloroprene Rubber." Rubber Chemistry and Technology 62, no. 1 (March 1, 1989): 13–32. http://dx.doi.org/10.5254/1.3536230.
Full textAbstract:
Abstract Amine antioxidants are found to react with chloroprene (CR) type-W rubber with its reactive chlorine atoms. These reactions take place during high-shear mixing in a torque rheometer, or in a Winkworth mixer at higher temperature, or during the vulcanization of the elastomers at 160°C. Mixed alkyl, aryl secondary amines are shown to react only at the alkyl-substituted amino group. The concentrations of the bound antioxidants are estimated by IR spectroscopy after complete extraction. Monsanto Rheometer studies show that, in many cases, the crosslinking reaction of CR rubber, which takes place through the chlorine atom, is reduced by the presence of the antioxidants. The effectiveness of the rubber-bound antioxidant is assessed by accelerated oven aging and stress techniques. It is shown that immobilization of amine antioxidants by combining them with the network does not impair their antioxidant activity.
31
Bērziņa, Laima, and Inese Mieriņa. "Vanillic and Meldrum’s Acid Containing Antioxidant." Key Engineering Materials 933 (October 17, 2022): 162–68. http://dx.doi.org/10.4028/p-87z4f8.
Full textAbstract:
Oxidation is a natural part of the aerobic world. Usually oxidation is suppressed by adding various antioxidants. Although a huge amount of antioxidants is known, studies of more active antioxidants which could be used in smaller amounts are crucial. Previously we have demonstrated arylmethyl Meldrum`s acids as promising free radical scavengers. On the other hand various phenol type compounds represent one of the most diverse group of antioxidants. In this study, two types of antioxidants – 1,3-dicarbonyl and phenol – were combined in a single molecule to study the plausible synergistic effects. Vanillic acid was used as a phenolic antioxidant, and Meldrum’s acid was the 1,3-dicarbonyl type antioxidant. The target compound was synthesized in four steps, and its antiradical activity was assessed using the DPPH method. The antiradical activity of the synthesized antioxidant was higher than that of widely used BHT.
32
Khalil, Ibrahim, Wageeh A. Yehye, Alaitz Etxabide Etxeberria, Abeer A. Alhadi, Seyedehsara Masoomi Dezfooli, Nurhidayatullaili Binti Muhd Julkapli, Wan Jefrey Basirun, and Ali Seyfoddin. "Nanoantioxidants: Recent Trends in Antioxidant Delivery Applications." Antioxidants 9, no. 1 (December 26, 2019): 24. http://dx.doi.org/10.3390/antiox9010024.
Full textAbstract:
Antioxidants interact with free radicals, terminating the adverse chain reactions and converting them to harmless products. Antioxidants thus minimize the oxidative stress and play a crucial role in the treatment of free radicals-induced diseases. However, the effectiveness of natural and/or synthetic antioxidants is limited due to their poor absorption, difficulties to cross the cell membranes, and degradation during delivery, hence contributing to their limited bioavailability. To address these issues, antioxidants covalently linked with nanoparticles, entrapped in nanogel, hollow particles, or encapsulated into nanoparticles of diverse origin have been used to provide better stability, gradual and sustained release, biocompatibility, and targeted delivery of the antioxidants with superior antioxidant profiles. This review aims to critically evaluate the recent scientific evaluations of nanoparticles as the antioxidant delivery vehicles, as well as their contribution in efficient and enhanced antioxidant activities.
33
Soni, Kusum Soni, and Sangeeta Loonker. "An Approach to Leading Antioxidant Activity of Different Plants and Food Material: A Review." Oriental Journal Of Chemistry 38, no. 3 (June 30, 2022): 663–70. http://dx.doi.org/10.13005/ojc/380316.
Full textAbstract:
Antioxidants are molecules that battle against free radicals in the body. Free radicals are compounds that can damage the body if it gets too strong. They are associated with many illnesses such as diabetes, cardiovascular disease, and cancer etc. The body has its defense system against antioxidants to regulate free radicals. Antioxidants are also found in foods, particularly fruits, vegetables, and other substances based on herbs. Vitamins E and C are very important antioxidants. Plants have recently become a significant source of a surprising number of antioxidants that avoid the oxidative stress of free radicals. Natural chemicals, particularly those from medicinal plants, give many beneficial antioxidants. Antioxidant preservatives also play the main role in rising shelf life in food processing. Alcohol, green tea, cocoa, and dark chocolate are popular as strong antioxidant sources. Antioxidants can increase the self-life of both natural and processed foods. As a result, they're commonly employed as food additives. In these cases, the activity has been increased by the increasing use of three different methods.This review aims to determine the antioxidant activity of historically beneficial and modern medicinal plants.
34
Moslavac, Tihomir, Stela Jokić, Ana Mrgan, Štefica Grgić, Antun Jozinović, Drago Šubarić, and Jurislav Babić. "Utjecaj dodatka antioksidanasa na oksidacijsku stabilnost goveđeg loja." Meso 21, no. 1 (2019): 52–61. http://dx.doi.org/10.31727/m.21.1.4.
Full textAbstract:
Influence of antioxidants on oxidative stability of beef tallow Fats are contained in the majority of foods that are consumed daily. Beef tallow is one of the most complex fats found in nature. Tallow is subject to oxidation during the production, storage and heat treatment. This study researched the effect of natural antioxidants (rosemary extract type Oxy’Less CS and type StabilEnhance, sage extract, alpha tocopherol, mixture tocopherol) and synthetic antioxidants (PG, BHA) on the oxidative stability of beef tallow. The oxidative stability of beef tallow, with and without added antioxidant, was evaluated using the sustainability test at 98 oC. The results are expressed as peroxide value (mmol O2/kg) obtained after storing the sample for a certain period of time at the temperature of 98°C. The results showed that applied antioxidants successfully stabilized the beef tallow. Among natural antioxidants, rosemary extract type Oxy'Less CS showed a higher antioxidant activity in beef tallow. In comparison with other tested antioxidants, it achieved greater efficiency in protecting the beef tallow from oxidation. Synthetic antioxidants propyl galate and butylhydroxyanisole successfully increased the stability of beef tallow, whereby propyl galate showed a higher antioxidant activity.
35
Fujimoto, Taiki, and Hiroaki Gotoh. "Feature Selection for the Interpretation of Antioxidant Mechanisms in Plant Phenolics." Molecules 28, no. 3 (February 2, 2023): 1454. http://dx.doi.org/10.3390/molecules28031454.
Full textAbstract:
Antioxidants, represented by plant phenolics, protect living tissues by scavenging reactive oxygen species through diverse reaction mechanisms. Research on antioxidants is often individualized, for example, focusing on the evaluation of their activity against a single reactive oxygen species or examining the antioxidant properties of compounds with similar structures. In this study, multivariate analysis was used to comprehensively examine antioxidant properties. Eighteen features were selected to explain the results of the antioxidant capacity tests. These selected features were then evaluated by supervised learning, using the results of the antioxidant capacity assays. Dimension-reduction techniques were also used to represent the compound space with antioxidants as a two-dimensional distribution. A small amount of data obtained from several assays provided us with comprehensive information on the relationships between the structures and activities of antioxidants.
36
Zhou, Ying, Manal Khan, Ling Jiang, Chuhan Fu, Yumeng Dong, Liping Luo, Haoran Guo, et al. "The Current Status of Antioxidants in the Treatment of Vitiligo in China." Oxidative Medicine and Cellular Longevity 2022 (February 24, 2022): 1–13. http://dx.doi.org/10.1155/2022/2994558.
Full textAbstract:
Little is known about the use of antioxidants in the clinical treatment of vitiligo. To investigate the specific use of antioxidants in the treatment of vitiligo and the possible reasons behind its use in China, we conducted a prospective questionnaire-based study using an online questionnaire comprising 26 questions in 5 areas. A total of 323 clinical frontline dermatologists participated in this study. Differences among groups were compared using Pearson’s chi-square test. Ordinal logistic regression was used to develop knowledge–use multiple regression models. Among the 323 dermatologists, 293 (90.7%) approved the oxidative stress theory of vitiligo, and 182 (56.3%) encouraged the use of antioxidants for treating vitiligo; nonetheless, only 11.8% frequently treated vitiligo with antioxidants. Insufficient knowledge of antioxidants was a significant predictor of lower frequency of antioxidant usage (adjusted odds ratio, 0.401 [95% confidence interval, 0.256-0.629]; P < .001 ). The predictors associated with higher antioxidant efficacy included advanced or rapid progression, moderate or moderate-to-severe vitiligo, age of 0–2 years or 13–18 years, segmental vitiligo, oral and topical combination therapy, and course duration of <1 month. The use of antioxidants for treating vitiligo is highly encouraged; however, the rates of their clinical use are considerably low. Insufficient knowledge of antioxidants is associated with a lower frequency of antioxidant usage. The synergistic curative efficacy of antioxidants could be affected by the stage, type, severity, age of patients with vitiligo, and method of using antioxidants.
37
Kotha, Raghavendhar R., Fakir Shahidullah Tareq, Elif Yildiz, and Devanand L. Luthria. "Oxidative Stress and Antioxidants—A Critical Review on In Vitro Antioxidant Assays." Antioxidants 11, no. 12 (December 1, 2022): 2388. http://dx.doi.org/10.3390/antiox11122388.
Full textAbstract:
Antioxidants have been widely studied in the fields of biology, medicine, food, and nutrition sciences. There has been extensive work on developing assays for foods and biological systems. The scientific communities have well-accepted the effectiveness of endogenous antioxidants generated in the body. However, the health efficacy and the possible action of exogenous dietary antioxidants are still questionable. This may be attributed to several factors, including a lack of basic understanding of the interaction of exogenous antioxidants in the body, the lack of agreement of the different antioxidant assays, and the lack of specificity of the assays, which leads to an inability to relate specific dietary antioxidants to health outcomes. Hence, there is significant doubt regarding the relationship between dietary antioxidants to human health. In this review, we documented the variations in the current methodologies, their mechanisms, and the highly varying values for six common food substrates (fruits, vegetables, processed foods, grains, legumes, milk, and dairy-related products). Finally, we discuss the strengths and weaknesses of the antioxidant assays and examine the challenges in correlating the antioxidant activity of foods to human health.
38
Pokorný, J., Š. Schmidt, and H. T T Nguyen. "Functionality changes of natural antioxidants during food processing and storage." Czech Journal of Food Sciences 22, SI - Chem. Reactions in Foods V (January 1, 2004): S80—S83. http://dx.doi.org/10.17221/10617-cjfs.
Full textAbstract:
Food raw materials and products contain inhibitors of oxidation reactions, both in the lipidic phase and the aqueous phase. The most important inhibitors are phenolic antioxidants. During food processing and storage, concentrations of antioxidants in the two phases reach an equilibrium. Phenolics react with lipidic free radicals, being converted into antioxidant free radicals, quinones, polymers and copolymers. Some degradation products possess an antioxidant activity, too. The relative antioxidant activity decreases with decreasing concentration of oxygen in the system and with increasing temperature. Antioxidants are more rapidly decomposed in surface layers. Health aspects of antioxidant degradation products are often neglected as the safety of antioxidant degradation products is mostly unknown.
39
Madhab, Mausomi, Chhavi Mangla, S. Vijaya, Devidas Narhar Patil, Renju Ammu Joseph, S. Anuradha, Madhuri Rajendra Ekashinge, et al. "Different Biological Activities Especially Antioxidant Activity of Plant Based Functional Foods for Human Health." International Journal of Membrane Science and Technology 10, no. 4 (September 19, 2023): 2419–23. http://dx.doi.org/10.15379/ijmst.v10i4.3507.
Full textAbstract:
In recent years, the interest in plant-based functional foods with various biological activities, especially antioxidant properties, has grown exponentially due to their potential health benefits. Antioxidants play a crucial role in neutralizing harmful free radicals, which are reactive molecules that can cause cellular damage and contribute to various chronic diseases. Natural antioxidants are abundant in food and medicinal plants. These natural antioxidants, particularly polyphenols and carotenoids, have a variety of biological benefits, including anti-inflammatory, anti-aging, anti-atherosclerosis, and anticancer properties (Xu et al ., 2017). Fruits and vegetables are excellent sources of antioxidants because they contain a variety of antioxidant components. Fruits and vegetables have varying levels of antioxidant activity. Each fruit and vegetable contains a distinct type of antioxidant, and this might vary from species to species as well as climate to climate (Ravimannan et al ., 2017). The paper discusses the underlying principles of oxidative stress and the mechanisms by which antioxidants counteract its effects (Fang et al ., 2002). It delves into the various classes of antioxidants found in plant-based foods, such as polyphenols, carotenoids, flavonoids, vitamins (e.g., vitamin C and E), and trace minerals (e.g., selenium and zinc), explaining their diverse roles in protecting cells from oxidative damage (Peng et al., 2014). In this chapter we emphasize the vital role of plant-based functional foods as a source of natural antioxidants, contributing to the promotion of human health and well-being. Incorporating a diverse array of antioxidant-rich plant foods into the daily diet is crucial for supporting overall health and preventing chronic diseases.
40
Nelson, Ashlianne, Arvind Babu Rajendra Santosh, and Thaon Jones. "Review of salivary antioxidants and their barriers." Dental Journal 57, no. 2 (May 7, 2024): 74–79. http://dx.doi.org/10.20473/j.djmkg.v57.i2.p74-79.
Full textAbstract:
Background: Oxidative stress results from the imbalance between reactive oxygen species (ROS) and cellular antioxidant defenses. Oxidative stress can cause damage to cellular structures such as cell membranes, lipids, proteins, lipoproteins, and deoxyribonucleic acids when free radicals are present in excess. Antioxidant mechanisms protect tissues against oxidative stress by decreasing free radical levels in cells through the inhibition of activities or expression of free radical-generating enzymes. Purpose: The purpose of this paper is to discuss the role of antioxidants in protecting cells from the harmful effects of ROS, particularly in the context of oral mucosa, and to clarify which molecules disrupt the pathway of these antioxidants. Review: Salivary peroxidase, catalase, superoxide dismutase, and glutathione reductase are enzymatic salivary antioxidants, and uric acid, reduced glutathione, albumin, and lactoferrin are non-enzymatic antioxidants. Both types of antioxidants regularly donate an electron to free radicals to reduce their levels in cells. Conclusion: Antioxidant activities may be disrupted by signaling mechanisms resulting from barrier regulations observed in tissue. The increased expression of malondialdehyde is an indicator of disrupted antioxidant barriers.
41
Meda, Srikala, Sharda Singh, Philip Palade, Sahil Tonk, and Sanjay Awasthi. "Oxidative stress in intensive care unit patients: a review of glutathione linked metabolism and lipid peroxidation." Southwest Respiratory and Critical Care Chronicles 7, no. 27 (January 18, 2019): 7–35. http://dx.doi.org/10.12746/swrccc.v7i27.511.
Full textAbstract:
Despite clear evidence of increased oxidative stress in the blood and tissues of critically ill intensive care unit patients, consistent beneficial effects of many different antioxidants have not been observed, and antioxidant therapy has not yet translated into widely accepted clinical practice. The reasons for this are unclear, likely rooted in the complex and context dependent free radical behavior of antioxidants interacting with the process of lipid peroxidation. Control of lipid peroxidation is a crucial requirement for the beneficial effects of antioxidants, but the interactions of biological antioxidant defenses with the potentially harmful free radical behavior of pharmacological antioxidants complicates the dose and selection of the optimal antioxidants. Glutathione, the primary small molecule antioxidant in biological systems, is the primary enzymatic oxidative stress defense that operates in the context of glutathione-linked antioxidant enzymes to metabolize many harmful products of lipid peroxidation to mercapturic acids. Recently, the mercapturic acid transporter protein, RLIP76 (human RALBP1 gene), has been shown to have a critical role in glutathione linked oxidative stress defenses. These findings provide a rationale for new approaches towards selection and dosing of antioxidant to improve their clinical benefit.
42
Sekti, Beta Herilla. "TEST OF ANTIOXIDANT CONTENT IN BLUE LOTUS (Nymphaea Stellata Wild) LEAVES WITH DPPH METHOD (1,1-Diphenyl-2-Picrylhydrazyl)." Jurnal Jamu Kusuma 1, no. 2 (December 31, 2021): 46–50. http://dx.doi.org/10.37341/jurnaljamukusuma.v1i2.10.
Full textAbstract:
Antioxidants are compounds materials that can inhibit the rate of oxidation of other molecules or neutralize free radicals. Antioxidants can be obtained in synthetic or natural forms. Natural antioxidants can protect the human body from damage to active oxygen which can inhibit degenerative diseases and inhibit the production of fat and food. Natural antioxidants can be obtained from plants, one of which is the Blue Lotus Plant (Nymphaea Stellata Wild). To ensure the presence of antioxidants in this plant, the antioxidant activity was tested using the DPPH method. The DPPH method was used to determine the free radical scavenging activity of the Ethanol Extract of Blue Lotus Leaf (Nymphaea Stellata Wild). The positive control used was Ascorbic Acid. The IC50 value obtained for testing the antioxidant content of blue lotus leaf is 78.405 ppm ± 24.607. And Ascorbic Acid 2,238 ppm. It can be concluded that the antioxidant activity of Blue Lotus Leaf is not too different from the positive control of ascorbic acid. The antioxidant activity of blue lotus leaf was stated to be strong and ascorbic acid was stated to be very strong.
Keywords: Antioxidant, Free radicals, DPPH
43
Wu, Shutian, Runhong Mo, Ruohui Wang, Qingyang Li, Danyu Shen, and Yihua Liu. "Identification of Key Antioxidants of Free, Esterified, and Bound Phenolics in Walnut Kernel and Skin." Foods 12, no. 4 (February 15, 2023): 825. http://dx.doi.org/10.3390/foods12040825.
Full textAbstract:
Walnut is a natural source of antioxidants. Its antioxidant capacity is determined by the distribution and composition of phenolics. The key phenolic antioxidants in various forms (free, esterified, and bound) in walnut kernel (particularly seed skin) are unknown. The phenolic compounds in twelve walnut cultivars were analyzed using ultra-performance liquid chromatography coupled with a triple quadrupole mass spectrometer in this study. A boosted regression tree analysis was used to identify the key antioxidants. Ellagic acid, gallic acid, catechin, ferulic acid, and epicatechin were abundant in the kernel and skin. The majority of phenolic acids were widely distributed in the free, esterified, and bound forms in the kernel but more concentrated in bound phenolics in the skin. The total phenolic levels of the three forms were positively correlated with antioxidant activities (R = 0.76–0.94, p < 0.05). Ellagic acid was the most important antioxidant in the kernel, accounting for more than 20%, 40%, and 15% of antioxidants, respectively. Caffeic acid was responsible for up to 25% of free phenolics and 40% of esterified phenolics in the skin. The differences in the antioxidant activity between the cultivars were explained by the total phenolics and key antioxidants. The identification of key antioxidants is critical for new walnut industrial applications and functional food design in food chemistry.
44
Taufiq, Nuramaniyah, and Sulfiani Sulfiani. "Antioxidant Activity of Ethanol and n-hexane Extracts of Javanese Bark (Lannea coromandelica) Using the DPPH Method." Indo. J. Chem. Res. 11, no. 1 (May 19, 2023): 43–48. http://dx.doi.org/10.30598//ijcr.2023.11-tau.
Full textAbstract:
Javanese bark (Lannea coromandelica) contains secondary metabolites of saponins, tannins, phenolics, and flavonoids. Flavonoids include aromatic compounds that are antioxidants. Antioxidants can inhibit the oxidation process that arises due to free radical reactions to form unreactive compounds. The active flavonoid compounds in counteracting free radicals are determined by the presence of the –OH (hydroxy) functional group. Flavonoid compounds that have antioxidant properties include catechins, flavones, flavanones, flavonols, chalcones, and isoflavones. This study aims to determine the antioxidant activity of ethanol extract and n-hexane bark of Javan bark (Lannea coromandelica) using the DPPH method. The method used is DPPH using UV-VIS spectrophotometry. Ethanol extract has an IC50 of 3.996 mg/L and has a strong antioxidant activity while the antioxidant activity of N-Hexan is obtained IC50 2193.043 mg/L. has weak antioxidants weak antioxidants.
45
Suliasih, Babay Asih, Setia Budi, and Haliza Katas. "Synthesis and application of gold nanoparticles as antioxidants." Pharmacia 71 (May 23, 2024): 1–19. http://dx.doi.org/10.3897/pharmacia.71.e112322.
Full textAbstract:
Non-communicable diseases (NCDs) and premature aging, caused by free radicals, have spurred a demand for extensive research into finding effective antioxidants. Currently, there is an abundance of both natural and synthetic antioxidants, including metal nanoparticles with high antioxidant activity. Among these, gold nanoparticles (AuNPs) stand out as favoured antioxidants because of their minimal toxicity, simple synthesis, and detectability. The antioxidant properties of AuNPs enhance its wide-ranging potential for use in healthcare including applications as anti-aging, anti-inflammatory, and wound healing agents, as well as treatment for various diseases. This review highlights recent progress in the synthesis of AuNPs as antioxidants and method for assessing their antioxidant capacity as well as delves into their mechanism of action and explores their potential health applications. In conclusion, considering the physicochemical and biological properties, along with the benefits and potential challenges for future development, AuNPs are deemed promising and effective antioxidants suitable for clinical applications.
46
Apak, Reşat, Shela Gorinstein, Volker Böhm, Karen M. Schaich, Mustafa Özyürek, and Kubilay Güçlü. "Methods of measurement and evaluation of natural antioxidant capacity/activity (IUPAC Technical Report)." Pure and Applied Chemistry 85, no. 5 (February 26, 2013): 957–98. http://dx.doi.org/10.1351/pac-rep-12-07-15.
Full textAbstract:
The chemical diversity of natural antioxidants (AOXs) makes it difficult to separate, detect, and quantify individual antioxidants from a complex food/biological matrix. Moreover, the total antioxidant power is often more meaningful to evaluate health beneficial effects because of the cooperative action of individual antioxidant species. Currently, there is no single antioxidant assay for food labeling because of the lack of standard quantification methods. Antioxidant assays may be broadly classified as the electron transfer (ET)- and hydrogen atom transfer (HAT)-based assays. The results obtained are hardly comparable because of the different mechanisms, redox potentials, pH and solvent dependencies, etc. of various assays. This project will aid the identification and quantification of properties and mutual effects of antioxidants, bring a more rational basis to the classification of antioxidant assays with their constraints and challenges, and make the results more comparable and understandable. In this regard, the task group members convey their own experiences in various methods of antioxidants measurement.
47
Tantowi, Ferdy, and David Limanan. "Antioxidant Test, Total Alkaloid Content, Antimitosis Test and HPTLC Test of Chamomile Flower Extract (Matricaria Chamomilla L.)." Devotion Journal of Community Service 4, no. 1 (January 12, 2023): 78–87. http://dx.doi.org/10.36418/dev.v4i1.351.
Full textAbstract:
Oxygen is one of the supports of multicellular life and is necessary for aerobic metabolism. However, the use of oxygen can produce by-products, one of which is reactive oxygen species (ROS) which can also increase due to external factors such as exposure to ionizing rays, and vehicle smoke. When reactive oxygen species levels are high, the body can experience a condition called oxidative stress, which is a condition that can cause tissue damage. To overcome this, antioxidants are needed, namely compounds that can donate electrons to free radicals to neutralize their effects. Antioxidants are divided into endogenous antioxidants and exogenous antioxidants. Endogenous antioxidants are antioxidants found in the body. Exogenous antioxidants are antioxidants that come from outside the body. Because there is an increase in ROS levels due to external influences, an increase in exogenous antioxidants is needed, one of which is chamomile flowers. This study evaluated qualitative phytochemical levels using the Harnborne method, total antioxidant capacity using the Blois method, total quantitative levels of alkaloids using the Trivedi et al method, BSLT toxicity using the Meyer method, and fingerprint analysis using HPTLC. The obtained chamomile flowers are dried and extracted by maceration using methanol solvent. The test results on chamomile flowers revealed phytochemical content in the form of alkaloids, betasianin, cardioglycosides, coumarins, flavonoids, phenols, quinones, saponins, steroids, tepenoids and tannins. Antioxidant ability 209.27 g/ml; Total alkaloid content of 12.62 g/ml; toxicity 174.39 g/mL; As well as fingerprint analysis chamomile flowers have active ingredients. Therefore, chamomile flowers can serve as a moderate antioxidant with antimitotic activity.
48
Mohammadian, Kiana, Fatemeh Fakhar, Shayan Keramat, and Agata Stanek. "The Role of Antioxidants in the Treatment of Metabolic Dysfunction-Associated Fatty Liver Disease: A Systematic Review." Antioxidants 13, no. 7 (June 29, 2024): 797. http://dx.doi.org/10.3390/antiox13070797.
Full textAbstract:
Non-alcoholic fatty liver disease (NAFLD) is a global public health problem that causes liver-related morbidity and mortality. It is also an independent risk factor for non-communicable diseases. In 2020, a proposal was made to refer to it as “metabolic dysfunction-associated fatty liver disease (MAFLD)”, with concise diagnostic criteria. Given its widespread occurrence, its treatment is crucial. Increased levels of oxidative stress cause this disease. This review aims to evaluate various studies on antioxidant therapies for patients with MAFLD. A comprehensive search for relevant research was conducted on the PubMed, SCOPUS, and ScienceDirect databases, resulting in the identification of 87 studies that met the inclusion criteria. In total, 31.1% of human studies used natural antioxidants, 53.3% used synthetic antioxidants, and 15.5% used both natural and synthetic antioxidants. In human-based studies, natural antioxidants showed 100% efficacy in the treatment of MAFLD, while synthetic antioxidants showed effective results in only 91% of the investigations. In animal-based research, natural antioxidants were fully effective in the treatment of MAFLD, while synthetic antioxidants demonstrated effectiveness in only 87.8% of the evaluations. In conclusion, antioxidants in their natural form are more helpful for patients with MAFLD, and preserving the correct balance of pro-oxidants and antioxidants is a useful way to monitor antioxidant treatment.
49
Jesus, Ana, Sandra Mota, Ana Torres, Maria T. Cruz, Emília Sousa, Isabel F. Almeida, and Honorina Cidade. "Antioxidants in Sunscreens: Which and What For?" Antioxidants 12, no. 1 (January 6, 2023): 138. http://dx.doi.org/10.3390/antiox12010138.
Full textAbstract:
Ultraviolet (UV) radiation promotes the generation of reactive oxygen species (ROS) and nitrogen species (RNS), resulting in skin damage. Cosmetic industries have adopted a strategy to incorporate antioxidants in sunscreen formulations to prevent or minimize UV-induced oxidative damage, boost photoprotection effectiveness, and mitigate skin photoaging. Many antioxidants are naturally derived, mainly from terrestrial plants; however, marine organisms have been increasingly explored as a source of new potent antioxidant molecules. This work aims to characterize the frequency of the use of antioxidants in commercial sunscreens. Photoprotective formulations currently marketed in parapharmacies and pharmacies were analyzed with respect to the composition described on the label. As a result, pure compounds with antioxidant activity were found. The majority of sunscreen formulations contained antioxidants, with vitamin E and its derivatives the most frequent. A more thorough analysis of these antioxidants is also provided, unveiling the top antioxidant ingredients found in sunscreens. A critical appraisal of the scientific evidence regarding their effectiveness is also performed. In conclusion, this work provides an up-to-date overview of the use of antioxidants in commercial sunscreens for a better understanding of the advantages associated with their use in photoprotective formulations.
50
Pastor, Rosario, and Josep A. Tur. "Antioxidant Supplementation and Adaptive Response to Training: A Systematic Review." Current Pharmaceutical Design 25, no. 16 (August 23, 2019): 1889–912. http://dx.doi.org/10.2174/1381612825666190701164923.
Full textAbstract:
Background: Antioxidant supplementation has become a common practice among athletes to theoretically achieve a reduction in oxidative stress, promote recovery and improve performance. Objective: To assess the effect of antioxidant supplements on exercise. Methods: A systematic literature search was performed up to January 2019 in MEDLINE via EBSCO and Pubmed, and in Web of Sciences based on the following terms: “antioxidants” [Major] AND “exercise” AND “adaptation”; “antioxidant supplement” AND “(exercise or physical activity)” AND “(adaptation or adjustment)” [MesH]. Thirty-six articles were finally included. Results: Exhaustive exercise induces an antioxidant response in neutrophils through an increase in antioxidant enzymes, and antioxidant low-level supplementation does not block this adaptive cellular response. Supplementation with antioxidants appears to decrease oxidative damage blocking cell-signaling pathways associated with muscle hypertrophy. However, upregulation of endogenous antioxidant enzymes after resistance training is blocked by exogenous antioxidant supplementation. Supplementation with antioxidants does not affect the performance improvement induced by resistance exercise. The effects of antioxidant supplementation on physical performance and redox status may vary depending on baseline levels. Conclusion: The antioxidant response to exercise has two components: At the time of stress and adaptation through genetic modulation processes in front of persistent pro-oxidant situation. Acute administration of antioxidants immediately before or during an exercise session can have beneficial effects, such as a delay in the onset of fatigue and a reduction in the recovery period. Chronic administration of antioxidant supplements may impair exercise adaptations, and is only beneficial in subjects with low basal levels of antioxidants.