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Relevant bibliographies by topics / Antifungal metabolites

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Academic literature on the topic 'Antifungal metabolites'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Antifungal metabolites"

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Lemriss, S., F. Laurent, A. Couble, E. Casoli, J. M. Lancelin, D. Saintpierre-Bonaccio, S. Rifai, A. Fassouane, and P. Boiron. "Screening of nonpolyenic antifungal metabolites produced by clinical isolates of actinomycetes." Canadian Journal of Microbiology 49, no. 11 (November 1, 2003): 669–74. http://dx.doi.org/10.1139/w03-088.

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The purpose of this work was to screen clinical isolates of actinomycetes producing nonpolyenic antifungals. This choice was made to limit the problem of rediscovery of well-known antifungal families, especially polyenic antifungals. One hundred and ten strains were tested, using two diffusion methods and two test media, against three yeast species and three filamentous fungi. Among 54 strains (49%) showing antifungal activity, five strains belonging to the genus Streptomyces were active against all test organisms and appeared promising. These results indicate that clinical and environmental isolates of actinomycetes could be an interesting source of antifungal bioactive substances. The production of nonpolyenic antifungal substances by these five active isolates was investigated using several criteria: antibacterial activity, ergosterol inhibition, and UV-visible spectra of active extracts. One active strain responded to all three selection criteria and produced potentially nonpolyenic antifungal metabolites. This strain was retained for further investigation, in particular, purification, structure elucidation, and mechanism of action of the active product.Key words: actinomycetes, Streptomyces, clinical isolates, antifungal, non-polyene.

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Kokil, Sachin, and Manish Bhatia. "Antifungal Azole Metabolites: Significance in Pharmaceutical and Biomedical Analysis." Journal of Medical Biochemistry 28, no. 1 (January 1, 2009): 1–10. http://dx.doi.org/10.2478/v10011-008-0040-1.

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Antifungal Azole Metabolites: Significance in Pharmaceutical and Biomedical Analysis Individualised therapy and factors determining such variability among patients are confusing to both physicians and their patients because of the observed therapeutic, metabolic and toxic response. The same is true about antifungal azoles. They are under the influence and become targets of metabolic drug-drug interactions where more than one active form of the drug may be involved. The clinical relevance of these interactions may vary upon the azole involved and upon the intention of drug administration. The pharmacodynamics and pharmacokinetics of azole drugs as indicated by the reviewed data make the need for characterization of all their metabolites even more evident. The health care systems also emphasize the identification and quantitation of the metabolites for a comprehensive understanding of the biological safety of individual metabolites, thus, revealing the need and scope of bioanalytical research in metabolite and toxicity profiling of drugs. Availability of protocols for qualitative and quantitative characterization of all metabolites will have many applications for therapeutic drug monitoring, bioequivalence, toxicological and all related studies. Identification of metabolites may be done by a variety of chromatographic and spectroscopic techniques, either alone or in combination with other techniques. Conventional liquid chromatography has been exploited widely in the field of metabolite profiling. The arrival of hyphenated techniques has revolutionized metabolite profiling, by not only separating but also generating data for the structural identification of metabolites as well. Among all techniques, the most exploited are Liquid Chromatography-Mass Spectroscopy, Nuclear Magnetic Resonance spectroscopy, Liquid Chromatography-Nuclear Magnetic Resonance spectroscopy, Liquid Chromatography-Nuclear Magnetic Resonance spectroscopy-Mass Spectroscopy and Extraction-Nuclear Magnetic Resonance spectroscopy. This compilation provides a tool for the metabolic, bioanalytical and biomedical understanding of antifungal azole metabolites.

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Whyte, Authrine C., Katherine B. Gloer, James B. Gloer, Brenda Koster, and David Malloch. "New antifungal metabolites from the coprophilous fungus Cercophorasordarioides." Canadian Journal of Chemistry 75, no. 6 (June 1, 1997): 768–72. http://dx.doi.org/10.1139/v97-093.

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A chemical investigation of the coprophilous fungus Cercophorasordarioides has led to the isolation of arthrinone (1), a known fungal metabolite, and three new related compounds: 1-dehydroxyarthrinone (2), 3a,9a-deoxy-3a-hydroxy-1-dehydroxyarthrinone (3), and cerdarin (4). These metabolites were obtained from antifungal ethyl acetate extracts of liquid cultures of C. sordarioides through bioassay-guided fractionation, and their structures were assigned on the basis of 1D-NMR, HMQC, and HMBC results. Compounds 2 and 4 exhibited anti-Candida activity. Key words: antifungal, fungal metabolite, natural product, Cercophorasordarioides.

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Ghisalberti, Emilio L., and Catherine Y. Rowland. "Antifungal Metabolites from Trichoderma harzianum." Journal of Natural Products 56, no. 10 (October 1993): 1799–804. http://dx.doi.org/10.1021/np50100a020.

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Pacciaroni, Adriana del V., María de los Angeles Gette, Marcos Derita, Luis Ariza-Espinar, Roberto R. Gil, Susana A. Zacchino, and Gloria L. Silva. "Antifungal activity ofHeterothalamus alienus metabolites." Phytotherapy Research 22, no. 4 (2008): 524–28. http://dx.doi.org/10.1002/ptr.2380.

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Ragasa, Consolacion Y., Angel Lyn Kristin C. Co, and John A. Rideout. "Antifungal metabolites from Blumea balsamifera." Natural Product Research 19, no. 3 (April 1, 2005): 231–37. http://dx.doi.org/10.1080/14786410410001709773.

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Buatong, Jirayu, Vatcharin Rukachaisirikul, Suthinee Sangkanu, Frank Surup, and Souwalak Phongpaichit. "Antifungal Metabolites from Marine-Derived Streptomyces sp. AMA49 against Pyricularia oryzae." Journal of Pure and Applied Microbiology 13, no. 2 (June 30, 2019): 653–65. http://dx.doi.org/10.22207/jpam.13.2.02.

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Broberg, Anders, Karin Jacobsson, Katrin Ström, and Johan Schnürer. "Metabolite Profiles of Lactic Acid Bacteria in Grass Silage." Applied and Environmental Microbiology 73, no. 17 (July 6, 2007): 5547–52. http://dx.doi.org/10.1128/aem.02939-06.

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ABSTRACT The metabolite production of lactic acid bacteria (LAB) on silage was investigated. The aim was to compare the production of antifungal metabolites in silage with the production in liquid cultures previously studied in our laboratory. The following metabolites were found to be present at elevated concentrations in silos inoculated with LAB strains: 3-hydroxydecanoic acid, 2-hydroxy-4-methylpentanoic acid, benzoic acid, catechol, hydrocinnamic acid, salicylic acid, 3-phenyllactic acid, 4-hydroxybenzoic acid, (trans, trans)-3,4-dihydroxycyclohexane-1-carboxylic acid, p-hydrocoumaric acid, vanillic acid, azelaic acid, hydroferulic acid, p-coumaric acid, hydrocaffeic acid, ferulic acid, and caffeic acid. Among these metabolites, the antifungal compounds 3-phenyllactic acid and 3-hydroxydecanoic acid were previously isolated in our laboratory from liquid cultures of the same LAB strains by bioassay-guided fractionation. It was concluded that other metabolites, e.g., p-hydrocoumaric acid, hydroferulic acid, and p-coumaric acid, were released from the grass by the added LAB strains. The antifungal activities of the identified metabolites in 100 mM lactic acid were investigated. The MICs against Pichia anomala, Penicillium roqueforti, and Aspergillus fumigatus were determined, and 3-hydroxydecanoic acid showed the lowest MIC (0.1 mg ml−1 for two of the three test organisms).

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Koval, Daniel, Milada Plocková, Jan Kyselka, Pavel Skřivan, Marcela Sluková, and Šárka Horáčková. "Buckwheat Secondary Metabolites: Potential Antifungal Agents." Journal of Agricultural and Food Chemistry 68, no. 42 (September 28, 2020): 11631–43. http://dx.doi.org/10.1021/acs.jafc.0c04538.

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Coleman, Jeffrey J., Suman Ghosh, Ikechukwu Okoli, and Eleftherios Mylonakis. "Antifungal Activity of Microbial Secondary Metabolites." PLoS ONE 6, no. 9 (September 22, 2011): e25321. http://dx.doi.org/10.1371/journal.pone.0025321.

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Dissertations / Theses on the topic "Antifungal metabolites"

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Cecotti, Roberto. "Antifungal secondary metabolites from some Indian Labiatae." Thesis, University of Strathclyde, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248262.

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Woods, Caroline M. "The fungal ecology of Sitka spruce stumps." Thesis, University of Aberdeen, 1996. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU083296.

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A study of the fungal ecology of Picea sitchensis stumps on mineral soils on first rotation sites in Scotland was carried out to determine fungal colonization, succession and the mechanisms of fungal interaction. Fungal and bacterial colonization of stump and buttress roots of stumps 0, 7, 28 days, 12, 16 and 48/53 months old was assessed. Melanotus proteus was found in all 12 month old stumps; Sistotrema brinkmanni was recorded most frequently in 16 and 48/53 month old stumps. A series of in vitro experiments was carried out to identify interactions occurring between pairs of P. sitchensis fungi on Norkrans agar, P. sitchensis sawdust, root blocks and billets, to determine possible modes of interaction occurring in vivo. Fungi exhibiting antagonism toward Heterobasidion annosum in vitro were noted to determine possible in vivo applications as curative/preventative biological controls against H. annosum. Sitka spruce stumps were highly receptive to H. annosum basidiospore infection up to 24 hours after felling and showed a significant level of receptivity 7 days after felling. M. proteus infection was lower in live stumps, compared to dead or moribund stumps, and was reduced or inhibited in stumps inoculated with Resinicium bicolor sawdust inoculum. In vitro experiments indicated that 5% urea prevented M. proteus basidiospore germination and hyphal growth. Treating stumps or billets with a 20% urea solution, however, had no significant effect on M. proteus colonization. Antifungal metabolites were detectable in 85% of the 25 fungal species tested representing members of the Basidiomycotina, Deuteromycotina and Ascomycotina, when bioassayed with Cladosporium cucumerinum. The production of antifungal metabolites in Sitka spruce stumps by H. annosum, R. bicolor, Stereum sanguinolentum, M. proteus and Hypholoma fasciculare was demonstrated.

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McEwan, Michael. "The antifungal effects of plant essential oils and their production by transformed shoot culture." Thesis, University of Strathclyde, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246327.

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Boonlarppradab, Chollaratt. "Investigation of the potential anticancer and antifungal active secondary metabolites from marine natural products." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3274752.

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Thesis (Ph. D.)--University of California, San Diego, 2007.
Title from first page of PDF file (viewed October 5, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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Constabel, Carsten Peter. "Studies on thiarubrine, a naturally occurring disulfide polyine." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27861.

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Chemical and biological aspects of thiarubrine, a highly antifungal dithiacyclohexadiene polyine, were investigated. A tissue culture system for the production of thiarubrines was developed by culturing hairy roots of Chaenactis douglasii induced by Agrobacterium rhizogenes strain TR7. One culture line accumulated two times the levels of thiarubrines of nontransformed control root cultures, while maintaining rapid growth. The combination of fast growth and high thiarubrine accumulation could not be duplicated in controls by adding exogenous NAA to the culture medium. Hairy root cultures also produced less thiarubrine B relative to thiarubrine A compared to controls. Thiarubrine synthesis appears to be closely correlated with degree of tissue differentiation; it is suggested that it may be more practical to improve the growth rate of thiarubrine-producing root cultures by transformation rather than seek to induce synthesis in fast-growing suspension cultures. The biosynthetic relation between thiarubrines and the always co-occurring thiophenes was investigated by performing ³⁵S tracer experiments with C. douglasii hairy root cultures. It is possible that the thiophenes are not actively synthesized by the roots but rather are products of thiarubrine decomposition resulting from the extraction procedures and other manipulations of the cultures. The in vitro conversion of thiarubrine to thiophene can be induced by light, heat and other agents. No turnover of thiarubrines could be detected in the cultures in late logarithmic or stationary phases of the growth cycle. I Thiarubrines show strong light-independent antibacterial and antifungal activity. The mechanism of action of thiarubrine against E. coli and S. cerevisiae was investigated using comparative disk bioassays. A very similiar polyine from Rudbeckia hirta was as active as thiarubrine in the dark, indicating the central role of the disulfide ring in toxicity of the compounds. Visible light enhanced this activity suggesting that decomposition of the disulfide ring is important for its antibiotic effects. The photodegradation product, a thiophene, is phototoxic, probably via both type I and type II photosensitization mechanisms. The root culture extracts of Rudbeckia hirta yielded a new isomer of a known dithiacyclohexadiene polyine. MS and NMR analyses confirmed the cis configuration of this isomer.
Science, Faculty of
Botany, Department of
Graduate

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6

Sjögren, Jörgen. "Bioassay-guided isolation and characterisation of antifungal metabolites : studies of lactic acid bacteria and propionic acid bacteria /." Uppsala : Dept. of Chemistry, Swedish University of Agricultural Sciences, 2005. http://epsilon.slu.se/200517.pdf.

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Egan, Suhelen Microbiology &amp Immunology UNSW. "Production and regulation of fouling inhibitory compounds by the marine bacterium Pseudoalteromonas tunicata." Awarded by:University of New South Wales. Microbiology and Immunology, 2001. http://handle.unsw.edu.au/1959.4/17838.

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The marine surface-associated bacterium Pseudoaltermonas tunicata, produces a range of compounds that inhibit fouling organisms, including invertebrate larvae, bacteria, algal spores and fungi. In addition to these antifouling compounds P. tunicata cells produce both a yellow and a purple pigment. The aim of this study was to further characterise the antifouling activities, their regulation and relationship with pigmentation, and the ecological significance of P. tunicata and related organisms. It was discovered that the anti-algal compound was extracellular, heat sensitive, polar and between 3 and 10 kDa in size. The anti-fungal compound was found to be the yellow pigment and active against a wide range of fungal and yeast isolates. Chemical analysis suggests that this compound consists of a carbon ring bound to a fatty-acid side chain. Genetic analysis supports the chemical data for the active compound as a mutant in a gene encoding for a long-chain fatty-acid CoA ligase was deficient for anti-fungal activity. To address the regulation of antifouling compounds and their relationship to pigmentation transposon mutagenesis of P. tunicata was performed. Mutants lacking the yellow pigment displayed a reduced ability to inhibit fouling organisms. Further analysis of these mutants identified genes involved with the synthesis and regulation of synthesis of pigment and antifouling compounds. One of these mutants was disrupted in a gene (wmpR) with similarity to the transcriptional regulators ToxR from Vibrio cholerae and CadC from Escherichia coli. Analysis of global protein expression using two-dimensional gel electrophoresis showed that WmpR is essential for the expression of at least fifteen proteins important for the synthesis of fouling inhibitors. The ecological significance of antifouling bacteria was addressed by assessing the antifouling capabilities of a collection of bacteria isolated from different marine surfaces. Overall, isolates from living surfaces displayed more antifouling traits then strains isolated from non-living surfaces. Five dark-pigmented strains originating from the alga Ulva lactuca were further studied. Phylogenetic and phenotypic analysis revealed that they were all members of the genus Pseudoalteromonas and were closely related to P. tunicata. Two strains represented a novel species within the genus and were taxonomically defined as P. ulvae sp. nov.

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8

Bahi, Muhammad [Verfasser], Hartmut [Akademischer Betreuer] Laatsch, and Axel [Akademischer Betreuer] Zeeck. "Bandamycin as New Antifungal Agent and further Secondary Metabolites from Terrestrial and Marine Microorganisms / Muhammad Bahi. Gutachter: Hartmut Laatsch ; Axel Zeeck. Betreuer: Hartmut Laatsch." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2012. http://d-nb.info/1043991387/34.

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Teixeira, Ana Frazão. "Metabólitos secundários de frutos da Virola molissima (Poepp. ex A. DC.) Warb.: neolignanas e atividade antifúngica." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/46/46135/tde-19102007-092413/.

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O uso de plantas na cura de enfermidades tem sido objeto de muitos estudos e desde épocas remotas está ligado ao desenvolvimento cultural de civilizações. Estudos anteriores em espécies de Myristicaceae descrevem a ocorrência da classe de lignóides como principal metabólito secundário. Variedades de estruturas químicas e de atividades biológicas são atribuídas aos lignóides. Estes metabólitos encontram-se acumulados em todas as partes da planta, principalmente nos frutos, onde os compostos predominantes são neolignanas. O presente trabalho foi realizado com Virola molissima que se encontra dispersa na Reserva Adolpho Ducke, situada nas proximidades de Manaus-AM. Os frutos foram coletados durante o mês de novembro, estação de seca na região. Não existe registro de estudo fitoquímico desta espécie. A partir de extratos de pericarpos, arilos, tegumentos e amêndoas dos frutos da Virola molissima foram isoladas por fracionamento cromatográfico as neolignanas tetrahidrofurânica, ariltetralônica e diarilbutânica. As neolignanas isoladas foram identificadas por comparação de seus dados de Ressonância Magnética Nuclear de Hidrogênio e de Carbono Treze, com aqueles descritos na literatura. A atividade antifúngica da neolignana ariltetralônica, pura ou em mistura, foi testada contra basidiomicetos Pycnoporus sanguineus, Trametes villosa e Lenzites trabeas. Estes fungos são xilófagos e causam o apodrecimento da madeira.
The use of plants in the treatment of diseases has been object of many studies, and since remote ages, the issue is linked to the cultural development of civilizations. Previous studies on Myristicaceous species described the occurrence of lignoids as its main secondary metabolites, which are known by varieties of chemical structures and biological activities. These lignoids are accumulated in all parts of the plant, mainly in the fruits, where the major constituent are neolignans. Present work was carried out on Virola molissima dispersed in Adolpho Ducke Reserve, located around Manaus, Amazon State, Brazil. Its fruits were collected during November, a month of dry season in this region. This species has not been phytochemically studied. Tetrahydrofuran, aryltetralone and dibenzylbutane neolignans were isolated from the extracts of pericarps, arils, seed coats and seeds of V. molissima fruits, by chromatographic fractionations. The structures of the isolated neolignans were elucidated through a Nuclear comparison between Magnetic Resonance of 1Hidrogen and 13Carbon data, and those described in the literature. The antifungal activity of the aryltetralone neolignan, pure or in mixture, was assayed against basidiomycetes Pycnoporus sanguineus, Trametes villosa and Lenzites trabeas. These fungi are xylophagus and they cause the decay of the wood.

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Oliveira, Ariana Reis Messias Fernandes de. "Morfoanatomia, composi??o qu?mica e atividade biol?gica do ?leo essencial de esp?cies nativas de Lippia." Universidade Estadual de Feira de Santana, 2014. http://localhost:8080/tede/handle/tede/219.

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The aim of this study was to characterize the morphology, production, content, chemical composition and bioactive activity of essential oils of Lippia bromleyana, Lippia lasiocalycina, Lippia insignis and Lippia thymoides, endemic species of the Bahia semi-arid. The species were grown in the Experimental Station Horto Florestal State University of Feira de Santana (UEFS) in the city of Feira de Santana - Bahia. The essential oils are extracted from dry leaves and inflorescences, by hydrodistillation in Clevenger apparatus, and chemical composition was determined by GC/MS and GC/FID. Were carried out quantitative and qualitative morphological characterizations, in addition to agronomic characterization. The leaf anatomy, types and frequency of hair were observed in binocular microscope and electronic scanning light. The antioxidant activity was assessed by the ability of the substances present in the sample capture the free radical DPPH, using five concentrations of essential oils (2, 6, 10, 14 and 18 mg mL1) and the antifungal activity by mycelium growth in vitro testing five essential oil concentrations (0.25, 0.50, 0.75, 1.0 and 1.25 ?L mL-1). In conditions where the study was conducted, it can be concluded that there are morphological differences between species in all traits, except only the number of flowers per inflorescence; there agronomic differences for all traits with L. lasiocalycina stood out in relation to the variable oil yield, while L. insignis and L. thymoides regarding the essential oil content; were identified six types of glandular trichomes one, two and tetracelular and three types of trichomes; the species L. bromleyana presents as differential anatomical absence of trichomes on the abaxial surface; L. thymoides has glandular trichomes with irregular contours on both sides, distinguishing it from other species; the frequency of trichomes on the abaxial surface is higher in species L. insignis and L. lasiocalycina, which are more anatomically similar; the major compounds found in the samples of essential oils of L. bromleyana, L. lasiocalycina, L. insignis and L. thymoides were piperitone oxide and limonene; E-ocimenona, myrcenone, myrcene, ?-myrcene and ?-cymene; thymol, myrcenone and E-ocimenona; and ?-caryophyllene, germacrene D, respectively; L. insignis and L. bromleyana stood out in relation to the antioxidant and antifungal activity, respectively.
O objetivo desse trabalho foi caracterizar a morfologia e a produ??o, teor, composi??o qu?mica e atividade bioativa de ?leos essenciais de Lippia bromleyana, Lippia lasiocalycina, Lippia insignis e Lippia thymoides, esp?cies end?micas do semi?rido baiano. As esp?cies foram cultivadas na Unidade Experimental Horto Florestal da Universidade Estadual de Feira de Santana (UEFS), na cidade de Feira de Santana ? Bahia. Os ?leos essenciais foram extra?dos de folhas e infloresc?ncias secas, por meio da hidrodestila??o em aparelho de Clevenger e a composi??o qu?mica determinada por CG/EM e CG/DIC. Foram realizadas caracteriza??es morfol?gicas quantitativas e qualitativas, al?m da caracteriza??o agron?mica. A anatomia foliar, tipos e frequ?ncia de tricomas foram observados em microsc?pio de luz binocular e eletr?nico de varredura. A atividade antioxidante foi avaliada pela capacidade das subst?ncias presentes na amostra captarem o radical livre DPPH, utilizando cinco concentra??es dos ?leos essenciais (2, 6, 10, 14 e 18 mg mL-1) e a atividade antif?ngica pelo crescimento miceliano in vitro, testando cinco concentra??es do ?leo essencial (0,25, 0,50, 0,75, 1,0 e 1,25 ?L mL-1). Nas condi??es em que foi realizado o estudo, pode-se concluir que existem diferen?as morfol?gicas entre as esp?cies em todas as caracter?sticas avaliadas, com exce??o apenas para o n?mero de flores por infloresc?ncia; existem diferen?as agron?micas para todos os caracteres avaliados, sendo que L. lasiocalycina se destacou em rela??o ? vari?vel rendimento de ?leo, enquanto que L. insignis e L. thymoides em rela??o ao teor de ?leo essencial; foram identificados seis tipos de tricomas glandulares uni, bi e tetracelular e tr?s tipos de tricomas tectores; a esp?cie L. bromleyana apresenta como diferencial anat?mico aus?ncia de tricomas tectores na face abaxial; L. thymoides possui tricomas glandulares com contornos irregulares em ambas as faces, distinguindo-a das demais esp?cies; a frequ?ncia de tricomas tectores na face abaxial ? superior nas esp?cies L. insignis e L. lasiocalycina, as quais s?o mais semelhantes anatomicamente; os compostos majorit?rios encontrados nas amostras dos ?leos essenciais de L. bromleyana, L. lasiocalycina L. insignis e L. thymoides foram: ?xido de piperitona e limoneno; E-ocimenona, mircenona, mirceno, ?-mirceno e ?-cimeno; timol, mircenona e E-ocimenona; ?-cariofileno e germacreno D, respectivamente; L. insignis e L. bromleyana se destacaram em rela??o ? atividade antioxidante e antif?ngica, respectivamente.

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Books on the topic "Antifungal metabolites"

1

Razzaghi-Abyaneh, Mehdi, and Mahendra Rai, eds. Antifungal Metabolites from Plants. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1.

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Krupke, Oliver A. The significance of volatile antifungal metabolites produced by trichomerma harzianum biotype Th4, in green-mould disease of commercial mushroom crops. St. Catharines, Ont: Brock University, Dept. of Biological Sciences, 2001.

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A, Hunter P., Darby G. K, and Russell Nicholas J, eds. Fifty years of antimicrobials: Past perspectives and future trends : Fifty-third Symposium of the Society for General Microbiology held at the University of Bath April 1995. Cambridge: Cambridge University Press, 1995.

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Rai, Mahendra, and Mehdi Razzaghi-Abyaneh. Antifungal Metabolites from Plants. Springer, 2015.

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Antifungal Metabolites From Plants. Springer-Verlag Berlin and Heidelberg GmbH &, 2013.

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(Editor), P. A. Hunter, G. K. Darby (Editor), and N. J. Russell (Editor), eds. Fifty Years of Antimicrobials: Past Perspectives & Future Trends. Cambridge University Press, 1995.

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Book chapters on the topic "Antifungal metabolites"

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De Conti Lourenço, Roseli Maria, Patricia da Silva Melo, and Ana Beatriz Albino de Almeida. "Flavonoids as Antifungal Agents." In Antifungal Metabolites from Plants, 283–300. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_10.

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Svetaz, Laura, Marcos Derita, Ma Victoria Rodríguez, Agustina Postigo, Estefanía Butassi, Ma Victoria Castelli, Maximiliano Sortino, Elisa Petenatti, and Susana Zacchino. "Antifungal Compounds from Latin American Plants." In Antifungal Metabolites from Plants, 3–26. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_1.

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Meena, Ajay Kumar, Shahin Khan, Mruthyumjaya Meda Rao, Radha Krishna Reddy, and Madhan Mohan Padhi. "Antifungal Metabolites from Medicinal Plants used in Ayurvedic System of Medicine in India." In Antifungal Metabolites from Plants, 303–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_11.

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Jahan, Rownak, Taufiq Rahman, and Mohammed Rahmatullah. "Plants Used in Folk Medicine of Bangladesh for Treatment of Tinea Infections." In Antifungal Metabolites from Plants, 333–66. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_12.

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Matos, Olívia, Ana Magro, and António Mexia. "Usefulness of Plant Derived Products to Protect Rice Against Fungi in Western Europe." In Antifungal Metabolites from Plants, 369–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_13.

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Morcia, Caterina, Giorgio Tumino, and Valeria Terzi. "Plant Bioactive Metabolites for Cereal Protection Against Fungal Pathogens." In Antifungal Metabolites from Plants, 401–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_14.

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González-Aguilar, Gustavo A., María Roberta Ansorena, Gabriela E. Viacava, Sara I. Roura, and Jesús F. Ayala-Zavala. "Plant Essential Oils as Antifungal Treatments on the Postharvest of Fruit and Vegetables." In Antifungal Metabolites from Plants, 429–46. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_15.

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Viacava, Gabriela E., María Roberta Ansorena, Sara I. Roura, Gustavo A. González-Aguilar, and Jesús F. Ayala-Zavala. "Fruit Processing Byproducts as a Source of Natural Antifungal Compounds." In Antifungal Metabolites from Plants, 447–61. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_16.

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Razzaghi-Abyaneh, Mehdi, Masoomeh Shams-Ghahfarokhi, and Mahendra Rai. "Antifungal Plants of Iran: An Insight into Ecology, Chemistry, and Molecular Biology." In Antifungal Metabolites from Plants, 27–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_2.

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Oyetayo, Victor Olusegun, and Ayodele Oluyemisi Ogundare. "Antifungal Property of Selected Nigerian Medicinal Plants." In Antifungal Metabolites from Plants, 59–77. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38076-1_3.

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Conference papers on the topic "Antifungal metabolites"

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Kozitsyn, A. E., T. M. Sidorova, and A. M. Asaturova. "Scaling of the promising producer strains cultivation process of fungicidal metabolites." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.129.

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The optimal conditions in pilot bioreactors for deep cultivation of the genus Bacillus bacteria were selected according to a number of biotechnological parameters, and the dynamics of antifungal compounds synthesis in the process of the culture maintaining was monitored.

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Sidorova, T. M., V. V. Allakhverdyan, and A. M. Asaturova. "Antifungal metabolites role in the antagonistic activity of the promising Bacillus subtilisstrains." In CURRENT STATE, PROBLEMS AND PROSPECTS OF THE DEVELOPMENT OF AGRARIAN SCIENCE. Federal State Budget Scientific Institution “Research Institute of Agriculture of Crimea”, 2019. http://dx.doi.org/10.33952/09.09.2019.140.

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Sidorova, T. M., A. M. Asaturova, and A. I. Khomyak. "The influence of cultivation conditions of promising Bacillus subtilis strains on their ability to produce antifungal metabolites." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.230.

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Antifungal compounds, including surfactin and iturin A, are accumulated by B. subtilis BZR336g strain at the cultivation temperature of 20.0-25.0 °C and the nutrient medium acidity pH8.0, for B. subtilis BZR517 strain these parameters are 30.0-35.0 °C and pH8.0-10.0, respectively.

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Zedan, Randa Hisham, Zahoor Ul-Hassan, Roda Al-Thani, Quirico Migheli, and Samir Jaoua. "Biological Control of Mycotoxigenic Fungi and Ochratoxin by the In-Vitro Application of a Qatari Burkholderia cepacia Strain (QBC03)." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0091.

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Mycotoxins are secondary metabolites synthesized by mycotoxigenic fungi belonging mainly to three major fungal genera that are Aspergillus, Fusarium and Penicillium. The latter mycotoxigenic fungi contaminate plants and different food commodities and cause various health concerns (carcinogenicity, mutagenicity, nephrotoxicity, etc...) due to their corresponding mycotoxins. One of the most studied mycotoxins is ochratoxin A (OTA) owing to its toxicity level (classified in 2B group as possible human carcinogenic). To remediate the mycotoxins’ contamination, physical and chemical techniques can be proposed. However, the safest among all is the biological control approach. In this research, we have used the Qatari strain Burkholderia cepacia (QBC03) as a biological agent against mycotoxigenic fungi and the strain has possessed a wide antifungal spectrum against 21 species from different genera. Additionally, the antifungal activity of QBC03’s supernatant was explored on the fungal biomass and OTA synthesis of A. carbonarius in liquid media, and interestingly; both the biomass and OTA’s concentrations were massively reduced upon treatment. The effect of QBC03’s supernatant on the fungal spores’ germination was examined as well, and it was shown that the conidial germination was completely inhibited. Moreover, the supernatant of QBC03 has induced morphological alteration in the mycelia of the fungal strain. The thermal stability of the antifungal compounds in QBC03’s culture supernatant was investigated, and it was shown that metabolites of QBC03 were distinctively thermostable and they were still active even when heated at 100C. The findings of this research prove that Burkholderia cepacia strain QBC03 is an excellent candidate for the biological control of mycotoxigenic fungi and their mycotoxins particularly in local regions.

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Alasmar, Reem Moath, and Samir Jaoua. "Investigation and Biological Control of Toxigenic Fungi and Mycotoxins in Dairy Cattle Feeds." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0065.

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Mycotoxins, the secondary fungal metabolites are important contaminants of food and feed. Among the other contaminants, aflatoxin B1 (AFB1) and OTA are frequently detected in the animal feed product. In the present study, the mixed dairy cow feed products were collected from the supermarkets in Qatar and analyzed for the presence of AFB1 and OTA. Yeast strains were isolated and tested for their biological control activities against aflatoxigenic and ochratoxin fungi. We demonstrated that local 15 yeasts isolates have important antifungal potential activities through the synthesis of volatile organic compounds (VOC) that are able to act against the mycotoxigenic fungi and their synthesis of the mycotoxins. Two Yeast strains (4&2) isolated from fermented food, have shown a great antifungal inhibition growth in-vitro as well as spores inhibition and mycotoxins synthesis.

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Cao, Ning-Ning, Xun-Li Liu, Nan Zhang, Qi-Sheng Zhou, Sha-Sha Zhang, and Hui Guo. "Medium optimization of antifungal metabolites produced by Bacillus globisporus A95 using response surface methodology." In 2010 Sixth International Conference on Natural Computation (ICNC). IEEE, 2010. http://dx.doi.org/10.1109/icnc.2010.5582902.

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Popovici, Violeta, Laura Bucur, Gabriela Vochita, Victoria Badea, and Florin-Ciprian Badea. "CONTRIBUTIONS TO THE COMPLEX STUDY ON ANTITUMOR ACTIVITY OF USNEA BARBATA (L.) F.H.WIGG." In NORDSCI International Conference. SAIMA Consult Ltd, 2020. http://dx.doi.org/10.32008/nordsci2020/b1/v3/25.

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Usnea barbata (L.)F.H.Wigg. - known as “old man’s beard”, “tree moss”, “songluo” is a lichen in the family Parmeliaceae, genus Usnea. Usnea species have recorded history of therapeutic use dating back over three thousand years in Chinese medicine. The lichen secondary metabolites have shown an impressive range of biological proprieties, including antibiotic, antifungal, antiviral, anti-inflammatory, or anticancer activities. In this study, the antitumor activity of Usnea barbata extract was evaluated by observing the morphological changes on squamous cells carcinoma cell-line CAL 27 (ATCC® CRL-2095 ™) in contact with different concentrations of extract, ranged between 12.5–400 μg/mL. The results obtained were quantified by the intensity of morphological changes of the tumor cells after 24 hours of contact. The most significant activity were recorded for 400 μg/mL extract. This study shows that Usnea barbata (L.)F.H.Wigg. extract has antitumor activity. The analysis of the obtained results showed that the cytotoxicity of lichen extract on CAL 27 tumor cells is directly related to the concentration of the applied solution.

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