Relevant bibliographies by topics / Anti-Taxonomy / Journal articles

Journal articles on the topic 'Anti-Taxonomy'

To see the other types of publications on this topic, follow the link: Anti-Taxonomy.
Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Anti-Taxonomy.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Leberknight, Christopher S., Mung Chiang, and Felix Ming Fai Wong. "A Taxonomy of Censors and Anti-Censors." International Journal of E-Politics 3, no. 2 (April 2012): 52–64. http://dx.doi.org/10.4018/jep.2012040104.

Full text
Abstract:
The tug-of-war on the Internet between censor and anti-censor technologies is intensifying. With an aim to raise awareness on Internet censorship and its circumvention, this paper and its companion Part II present a conceptual study of Internet censorship and anti-censorship. This first paper focuses on Internet censorship. It outlines an historical account of censorship through the lens of news coverage in the past decade, and presents a taxonomy of the principles, techniques, and technologies of Internet censorship. The interplay between social, political, and technological factors is presented to highlight the challenges in anti-censorship. Part II of the paper focuses on anti-censorship.
APA, Harvard, Vancouver, ISO, and other styles
2

Highland, Harold Joseph. "AIN'T misbehaving—A taxonomy of anti-intrusion techniques." Computers & Security 14, no. 7 (January 1995): 606. http://dx.doi.org/10.1016/0167-4048(96)81669-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Shih, Dong-Her, Po-Ling Sun, David C. Yen, and Shi-Ming Huang. "Taxonomy and survey of RFID anti-collision protocols." Computer Communications 29, no. 11 (July 2006): 2150–66. http://dx.doi.org/10.1016/j.comcom.2005.12.011.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Leberknight, Christopher S., Mung Chiang, and Felix Ming Fai Wong. "A Taxonomy of Censors and Anti-Censors Part II." International Journal of E-Politics 3, no. 4 (October 2012): 20–35. http://dx.doi.org/10.4018/jep.2012100102.

Full text
Abstract:
This paper presents a conceptual study of Internet anti-censorship technologies. It begins with an overview of previous research on Internet anti-censorship systems and discusses their social, political and technological dimensions. Then for deployed Internet anti-censorship technologies, a taxonomy of their principles and techniques is presented, followed by a discussion of observed trends and implications. Based on the observations, the paper concludes with a discussion on the most critical design features to enable a successful and effective system.
APA, Harvard, Vancouver, ISO, and other styles
5

Jacobson, Robert M., Paul V. Targonski, and Gregory A. Poland. "A taxonomy of reasoning flaws in the anti-vaccine movement." Vaccine 25, no. 16 (April 2007): 3146–52. http://dx.doi.org/10.1016/j.vaccine.2007.01.046.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Bowles, Paul. "Globalization and Neoliberalism: A Taxonomy and Some Implications for Anti-Globalization." Canadian Journal of Development Studies/Revue canadienne d'études du développement 26, no. 1 (January 2005): 67–87. http://dx.doi.org/10.1080/02255189.2005.9669026.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

ALEMANNO, Alberto. "How to Counter Fake News? A Taxonomy of Anti-fake News Approaches." European Journal of Risk Regulation 9, no. 1 (March 2018): 1–5. http://dx.doi.org/10.1017/err.2018.12.

Full text
Abstract:
AbstractFake news is a symptom of deeper structural problems in our societies and media environments. To counter it, policymakers need to take into account the underlying, self-reinforcing mechanisms that make this old phenomenon so pervasive today. Only by taking a step back can we examine the vulnerabilities these fake news narratives exploit. This article provides a first taxonomy of anti-fake news approaches. It argues that proposed anti-fake news laws focus on the trees rather than the forest. As such, they will not only remain irrelevant but also aggravate the root causes fuelling the fake news phenomenon.
APA, Harvard, Vancouver, ISO, and other styles
8

Conlan, Kevin, Ibrahim Baggili, and Frank Breitinger. "Anti-forensics: Furthering digital forensic science through a new extended, granular taxonomy." Digital Investigation 18 (August 2016): S66—S75. http://dx.doi.org/10.1016/j.diin.2016.04.006.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Roffee, James A., and Andrea Waling. "Rethinking microaggressions and anti-social behaviour against LGBTIQ+ youth." Safer Communities 15, no. 4 (October 10, 2016): 190–201. http://dx.doi.org/10.1108/sc-02-2016-0004.

Full text
Abstract:
Purpose The purpose of this paper is to further the understanding of experiences of anti-social behaviour in LGBTIQ+ youth in university settings. Design/methodology/approach The discussion reflects on qualitative interviews with LGBTIQ+ young people studying at university (n=16) exploring their experiences of anti-social behaviour including harassment, bullying and victimisation in tertiary settings. Findings The findings demonstrate that attention should be paid to the complex nature of anti-social behaviour. In particular, LGBTIQ+ youth documented experiences of microaggressions perpetrated by other members of the LGBTIQ+ community. Using the taxonomy of anti-social behaviour against LGBTIQ+ people developed by Nadal et al. (2010, 2011), the authors build on literature that understands microaggressions against LGBTIQ+ people as a result of heterosexism, to address previously unexplored microaggressions perpetrated by other LGBTIQ+ people. Research limitations/implications Future research could seek a larger sample of participants from a range of universities, as campus climate may influence the experiences and microaggressions perpetrated. Practical implications Individuals within the LGBTIQ+ community also perpetrate microaggressions against LGBTIQ+ people, including individuals with the same sexual orientation and gender identity as the victim. Those seeking to respond to microaggressions need to attune their attention to this source of anti-social behaviour. Originality/value Previous research has focused on microaggressions and hate crimes perpetrated by non-LGBTIQ+ individuals. This research indicates the existence of microaggressions perpetrated by LGBTIQ+ community members against other LGBTIQ+ persons. The theoretical taxonomy of sexual orientation and transgender microaggressions is expanded to address LGBTIQ+ perpetrated anti-social behaviour.
APA, Harvard, Vancouver, ISO, and other styles
10

Smith, Daniel A. "Peeling Away the Populist Rhetoric: Toward a Taxonomy of Anti-Tax Ballot Initiatives." Public Budgeting Finance 24, no. 4 (December 2004): 88–110. http://dx.doi.org/10.1111/j.0275-1100.2004.00349.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
11

GULLO, VINCENT, MICHAEL CONOVER, RAYMOND COOPER, CLAIRE FEDERBUSH, ANN C. HORAN, TED KUNG, JOSEPH MARQUEZ, MAHESH PATEL, and ARTHUR WATNICK. "Sch 36605, a novel anti-inflammatory compound. Taxonomy, fermentation, isolation and biological properties." Journal of Antibiotics 41, no. 1 (1988): 20–24. http://dx.doi.org/10.7164/antibiotics.41.20.

Full text
APA, Harvard, Vancouver, ISO, and other styles
12

Andreyeva, Elena A., Elmira I. Nazmieva, and Valentina M. Nasrtdinova. "Taxonomy of Values and Anti-Values: the Material of the Russian and German Phraseology." Journal of History Culture and Art Research 6, no. 5 (November 28, 2017): 301. http://dx.doi.org/10.7596/taksad.v6i5.1251.

Full text
Abstract:
<p>At present, in terms of intercultural communication, the role of the axiological aspect in teaching foreign languages is growing. When thinking about the values and anti-values in the phraseology of Russian and German it is advisable to take into account their hierarchy which can be presented as the axiological scale. This investigation benefits from the following methods: axiological linguistic method, method of cognitive analysis, comparative method, processing of lexicographical sources. The result of the study is formation of the axiological scale and development on its basis of the taxonomic model of values and anti-values in the phraseology of the Russian and German languages. The taxonomic model of values and anti-values in the phraseology of the language allows submitting axiological hierarchy reflecting the inter-layer differentiation of values and anti-values represented by axiological phraseology. Axiological scale and taxonomic model of values and anti-values in the Russian and German phraseology can be used in linguistic axiological research of different languages. </p>
APA, Harvard, Vancouver, ISO, and other styles
13

KATO, AZUSA, SEIGO NAKAYA, NAOMI KOKUBO, YUJI AIBA, YOSHITAMI OHASHI, HARUHISA HIRATA, KIYONAGA FUJII, and KEN-ICHI HARADA. "A New Anti-MRSA Antibiotic Complex, WAP-8294A. I. Taxonomy, Isolation and Biological Activities." Journal of Antibiotics 51, no. 10 (1998): 929–35. http://dx.doi.org/10.7164/antibiotics.51.929.

Full text
APA, Harvard, Vancouver, ISO, and other styles
14

Mete, Vittorio. "Four types of anti-politics: Insights from the Italian case." Modern Italy 15, no. 1 (February 2010): 37–61. http://dx.doi.org/10.1080/13532940903477872.

Full text
Abstract:
The wordantipolitica(‘anti-politics’) is widely used in contemporary Italian political debate. The concept of ‘anti-politics’ is also frequently used by social scientists in explaining the Italian political transition that took place during the 1990s and analysing the current political situation. In spite of this wide use, sociopolitical literature does not provide a consensual definition of the term. As result, the semantic field of the concept as yet appears poorly defined. This article provides a detailed look at the use of the term ‘anti-politics’ in the sociopolitical literature. Structuring the analysis around some basic conceptual distinctions, the article proposes a taxonomy of the meanings related to the term ‘anti-politics’, highlighting four different meanings of the concept. Referring in particular to the Italian political system, the article provides examples of the meanings of the concept of ‘anti-politics’ using phenomena occurring in the peninsula during the 1990s – phenomena which were central to the increasing use of the term in Italy during that decade.
APA, Harvard, Vancouver, ISO, and other styles
15

R, Anjum Sahair, Sneha S, Raghu N, Gopenath TS, Murugesan Karthikeyan, Ashok Gnanasekaran, Chandrashekrappa GK, and Kanthesh M. Basalingappa. "Solanum tuberosum L: Botanical, Phytochemical, Pharmacological and Nutritional Significance." International Journal of Phytomedicine 10, no. 3 (November 19, 2018): 115. http://dx.doi.org/10.5138/09750185.2256.

Full text
Abstract:
<p>Solanum tuberosum commonly known as potato belongs to solanaceae family. The whole part of potato plant including leaves; tuber, peel and juice are used in traditional medicine. A number of pharmacological activities of potato have been reported viz. Antioxidant, anticancer, antiallergy, antibacterial, anti-inflammatory, antiobesity, anti-ulcer activity. Potato contains Phenolic acids, anthocyanin, flavonoids, vitamin B6, vitamin B3, pantothenic acid, potassium, manganese, phosphorous; copper and fibres. The medicinal properties, traditional uses, nutritional value, phytochemical constituents, taxonomy, geographic origin and distribution have been mentioned in this present review to provide collective data for multipurpose benefits.</p><p> </p>
APA, Harvard, Vancouver, ISO, and other styles
16

NAKAO, MASAFUMI, KEN-ICHIRO MIYAGAWA, YOSHITAKA NAKANO, TAKESHI SAKANE, MAYUMI TADA, OSAMU NISHIMURA, and MASAHIKO FUJINO. "Pyloricidins, Novel Anti-Helicobacter pylori Antibiotics Produced by Bacillus sp. I. Taxonomy, Fermentation and Biological Activity." Journal of Antibiotics 54, no. 11 (2001): 926–33. http://dx.doi.org/10.7164/antibiotics.54.926.

Full text
APA, Harvard, Vancouver, ISO, and other styles
17

Biagioli, Michele, Chiara Fiorucci, Adriana Carino, Silvia Marchianò, Eleonora Distrutti, and Stefano Fiorucci. "Tu1748 - Probiotics Beyond Taxonomy: Evidence that Anti-inflammatory Properties of Live Biotherapeutic Products Require Phenotypic Characterization." Gastroenterology 154, no. 6 (May 2018): S—1008—S—1009. http://dx.doi.org/10.1016/s0016-5085(18)33374-2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
18

Ebbighausen, Volker, Ralph Thomas Becker, and Jürgen Bockwinkel. "Emsian and Eifelian ammonoids from Oufrane, eastern Dra Valley (Anti-Atlas, Morocco) – taxonomy, stratigraphy and correlation." Neues Jahrbuch für Geologie und Paläontologie - Abhandlungen 259, no. 3 (March 1, 2011): 313–79. http://dx.doi.org/10.1127/0077-7749/2011/0121.

Full text
APA, Harvard, Vancouver, ISO, and other styles
19

BORAH, Punam J., Dipankar BORAH, Udipta DAS, Tridip J. DAS, and Ruma SARMA. "A review on ethnopharmacological utility, traditional knowledge and phytochemistry of Aristolochia species in Assam, India." Notulae Scientia Biologicae 13, no. 3 (August 18, 2021): 11027. http://dx.doi.org/10.15835/nsb13311027.

Full text
Abstract:
Aristolochia L. (Aristolochiaceae) is widely used throughout South-East Asia for the treatment of several diseases. Different species of this genus are known by similar local names in Assam. This review aims to provide up-to-date information on Aristolochia species distributed in Assam, including its traditional uses, phytochemical and pharmacological properties, in exploring future therapeutic and scientific potentials. The information on ethnobotany, phytochemistry and pharmacological aspects were collected by performing literature searches. Assam hosts a total of six species of Aristolochia. The taxonomy and distribution are presented. Traditionally the tubers are used by the local people to treat stomach pain, malaria, dysentery, high blood pressure, body pain, urinary tract infections, headache, impotency etc. It has considerable pharmacological properties including antimicrobial, antioxidant, anti-inflammatory, anti-cancer, anti-diabetic, anti-fertility, anti-venom, anti-diarrhoeal, anti-pruritic, anti-feedant and toxicological activities. Approximately a total of 200 compounds have been isolated from these species. So far, pharmacological investigations are only done on three Aristolochia species, whereas the other three are simultaneously used for the same purposes. Most of the medicinal properties attributed to these Aristolochia, have not yet been investigated and proven under a scientific study. This highlights the importance of Aristolochia as a valuable candidate for future studies.
APA, Harvard, Vancouver, ISO, and other styles
20

J. Richardson, Alan. "The discovery of cumulative knowledge." Accounting, Auditing & Accountability Journal 31, no. 2 (February 19, 2018): 563–85. http://dx.doi.org/10.1108/aaaj-08-2014-1808.

Full text
Abstract:
Purpose The purpose of this paper is to provide guidance for designing and generating cumulative knowledge based on qualitative research. Design/methodology/approach The paper draws on the philosophy of science and specific examples of qualitative studies in accounting that have claimed a cumulative contribution to knowledge to develop a taxonomy of theoretically justified approaches to generating cumulative knowledge from qualitative research. Findings The paper argues for a definition of cumulative knowledge that is inclusive of anti-realist research, i.e. knowledge is cumulative if it increases the extent and density of intertextual linkages in a field. It identifies the possibility of cumulative qualitative research based on extensions to the scope of the knowledge and the depth of the knowledge. Extensions to the scope of the knowledge may include expanding the time periods, context, and/or theoretical perspective used to explore a phenomenon. Extensions to the depth of the knowledge may include new empirical knowledge, methodological pluralism, theory elaboration, or analytic generalization. Individual studies can demonstrate their contribution to cumulative knowledge by locating their research within a typology/taxonomy that makes explicit the relationship of current research to past, and potential, research. Research limitations/implications The taxonomy may be useful to qualitative researchers designing and reporting research that will have impact on the literature. Social implications The increased use of research impact as an evaluation metric has the potential to handicap the development qualitative research which is often thought of as generating non-cumulative knowledge. The taxonomy and the strategies for establishing cumulative impact may provide a means for this approach to research to establish its importance as a contribution to knowledge. Originality/value The concept of cumulative knowledge has not been systematically applied to research based on qualitative methods.
APA, Harvard, Vancouver, ISO, and other styles
21

Luo, Lu, Yixing Qiu, Limin Gong, Wei Wang, and Ruiding Wen. "A Review of Polygonatum Mill. Genus: Its Taxonomy, Chemical Constituents, and Pharmacological Effect Due to Processing Changes." Molecules 27, no. 15 (July 28, 2022): 4821. http://dx.doi.org/10.3390/molecules27154821.

Full text
Abstract:
Ethnopharmacological relevance: The genus Polygonatum Tourn, ex Mill. contains numerous chemical components, such as steroidal saponins, polysaccharides, flavonoids, alkaloids, and others, it possesses diverse pharmacological activities, such as anti-aging, anti-tumor, immunological regulation, as well as blood glucose management and fat reducing properties. Aim of the review: This study reviews the current state of research on the systematic categorization, chemical composition, pharmacological effects, and processing changes of the plants belonging to the genus Polygonatum, to provide a theoretical foundation for their scientific development and rational application. Materials and methods: The information was obtained by searching the scientific literature published between 1977 and 2022 on online databases (including PubMed, CNKI, SciFinder, and Web of Science) and other sources (such as the Chinese Pharmacopoeia 2020 edition, and Chinese herbal books). Results: The genus Polygonatum contains 79 species, and 233 bioactive chemical compounds were identified in them. The abundance of pharmacological activities, such as antioxidant activities, anti-fatigue activities, anti-inflammatory activities, etc., were revealed for the representatives of this genus. In addition, there are numerous processing methods, and many chemical constituents and pharmacological activities change after the unappropriated processing. Conclusions: This review summarizes the taxonomy classification, chemical composition, pharmacological effects, and processing of the plants belonging to the genus Polygonatum, providing references and research tendencies for plant-based drug development and further clinical applications.
APA, Harvard, Vancouver, ISO, and other styles
22

Torrens, Francisco, and Gloria Castellano. "Molecular Classification of 5-Amino-2-Aroylquinolines and 4-Aroyl-6,7,8-Trimethoxyquinolines as Highly Potent Tubulin Polymerization Inhibitors." International Journal of Chemoinformatics and Chemical Engineering 3, no. 2 (July 2013): 1–26. http://dx.doi.org/10.4018/ijcce.2013070101.

Full text
Abstract:
Algorithms for classification and taxonomy are proposed based on criteria as information entropy and its production. It is classified a series of 5-amino-2-aroylquinolines (AAQs) and 4-aroyl-6,7,8-trimethoxyquinolines (TMQs) combretastatin analogues for anti-cancer activity. 5-Amino-6-methoxy-2-aroylquinoline AAQ showed anti-proliferative activity more potent as compared to combretastatin A-4 (CA4), against various human cancer cell lines and a multidrug resistance (MDR) cancer cell line. On the basis of AAQ/TMQ structure–activity relationship new derivatives are designed. The AAQs/TMQs are classified using nine characteristic chemical properties in molecules. Many classification algorithms are based on information entropy. When applying the procedures to sets of moderate size, an excessive number of results appear compatible with data and suffer a combinatorial explosion. However, after equipartition conjecture, one has a selection criterion between different variants resulting from classification between hierarchical trees. A classification of anti-cancer agents is obtained. The features denote positions R2–8 on the quinoline bicycle.
APA, Harvard, Vancouver, ISO, and other styles
23

Kato, Azusa, Seigo Nakaya, Naomi Kokubo, Yuji Aiba, Yoshitami Ohashi, Haruhisa Hirata, Kiyonaga Fujii, and Ken-ichi Harada. "ChemInform Abstract: A New Anti-MRSA Antibiotic Complex, WAP-8294A. Part 1. Taxonomy, Isolation and Biological Activities." ChemInform 30, no. 12 (June 17, 2010): no. http://dx.doi.org/10.1002/chin.199912248.

Full text
APA, Harvard, Vancouver, ISO, and other styles
24

Gendron, Tracey, Alexa Van Aartjik, Kyrie Carpenter, Ryan Backer, and Ashton Applewhite. "Anti-Ageism Interventions: An Ecological Approach." Innovation in Aging 5, Supplement_1 (December 1, 2021): 429. http://dx.doi.org/10.1093/geroni/igab046.1668.

Full text
Abstract:
Abstract Ageism, discrimination based on age, is a systemic problem that occurs at multiple levels of the ecological system – meaning that ageism manifests at the individual, dyadic, institutional and societal levels. The expression of ageism within the levels of the ecological system makes ageism a continually shifting and dynamic force of oppression. Although ageism is a well-documented phenomenon with wide-reaching negative impacts, interventions to mitigate ageism’s effects remain understudied. Little is known about the taxonomy of interventions available addressing ageism at the individual, dyadic, subcultural, institutional and societal levels. The current study conducted a deductive content analysis of an anti-ageism resource clearinghouse, OldSchool.info, to evaluate ageism interventions using an ecological framework. Results indicate the majority of ageism interventions are passive-oriented societal-level macrosystem approaches. A gap analysis will be discussed that indicated more active-oriented interventions with engageable content to address ageism at the personal and relational levels are needed.
APA, Harvard, Vancouver, ISO, and other styles
25

Zhu, Bo, Sai Wang, Chun-Yi Mi, Rui-Huan Yang, Guo-Hong Zen, and Xiu-Fang Hu. "Genome Sequence Resource for Ilyonectria mors-panacis, Causing Rusty Root Rot of Panax notoginseng." Molecular Plant-Microbe Interactions® 32, no. 11 (November 2019): 1468–71. http://dx.doi.org/10.1094/mpmi-05-19-0118-a.

Full text
Abstract:
Ilyonectria mors-panacis is the cause of a serious disease hampering the production of Panax notoginseng, an important Chinese medicinal herb, widely used for its anti-inflammatory, antifatigue, hepato-protective, and coronary heart disease prevention effects. Here, we report the first Illumina-Pacbio hybrid sequenced draft genome assembly of I. mors-panacis strain G3B and its annotation. The availability of this genome sequence not only represents an important tool toward understanding the genetics behind the infection mechanism of I. mors-panacis strain G3B but also will help illuminate the complexities of the taxonomy of this species.
APA, Harvard, Vancouver, ISO, and other styles
26

TEA, YI-KAI, and ANTHONY C. GILL. "Systematic reappraisal of the anti-equatorial fish genus Microcanthus Swainson (Teleostei: Microcanthidae), with redescription and resurrection of Microcanthus joyceae Whitley." Zootaxa 4802, no. 1 (June 22, 2020): 41–60. http://dx.doi.org/10.11646/zootaxa.4802.1.3.

Full text
Abstract:
The taxonomy and classification of the microcanthid fish genus Microcanthus Swainson has been a subject of contention dating back to the 19th century. Its allopatric, disjunct anti-equatorial distribution across the Indo-West Pacific has resulted in the recognition of several nominal taxa, though these have been widely regarded as synonyms of Microcanthus strigatus (Cuvier). Following the results published in a companion study elsewhere by the authors, the taxonomy of Microcanthus and the validity of these nominal synonyms are herewith revised. Microcanthus strigatus is redescribed on the basis of 66 specimens from East Asia, Hawaii and Western Australia, and M. joyceae is resurrected and redescribed on the basis of 25 specimens from eastern Australia and the southwest Pacific. Microcanthus differs from other microcanthid genera in having the following combination of characters: dorsal-fin rays XI,15–17 (usually XI,16); anal-fin rays III,13–15 (usually III,14); pectoral-fin rays 15–17 (usually 16); scales ctenoid with ctenial bases present; lateral-line scales partially or heavily obscured by adjacent scales; and body pale in preservation with five horizontal dark stripes reaching the posterior edges of dorsal and anal fins, and base of caudal fin. The review is accompanied by a key to the genera of Microcanthidae.
APA, Harvard, Vancouver, ISO, and other styles
27

Tokumaru, Yoshihisa, Mariko Asaoka, Masanori Oshi, Eriko Katsuta, Li Yan, Sumana Narayanan, Nobuhiko Sugito, et al. "High Expression of microRNA-143 is Associated with Favorable Tumor Immune Microenvironment and Better Survival in Estrogen Receptor Positive Breast Cancer." International Journal of Molecular Sciences 21, no. 9 (May 1, 2020): 3213. http://dx.doi.org/10.3390/ijms21093213.

Full text
Abstract:
microRNA-143 (miR-143) is a well-known tumor suppressive microRNA that exhibits anti-tumoral function by targeting KRAS signaling pathways in various malignancies. We hypothesized that miR-143 suppresses breast cancer progression by targeting KRAS and its effector molecules. We further hypothesized that high expression of miR-143 is associated with a favorable tumor immune microenvironment of estrogen receptor (ER)-positive breast cancer patients which result in improved survival. Two major publicly available breast cancer cohorts; The Cancer Genome Atlas (TCGA) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) were used. The miR-143 high expression group was associated with increased infiltration of anti-cancer immune cells and decreased pro-cancer immune cells, as well as enrichment of the genes relating to T helper (Th1) cells resulting in improved overall survival (OS) in ER-positive breast cancer patients. To the best of our knowledge, this is the first study to demonstrate that high expression of miR-143 in cancer cells associates with a favorable tumor immune microenvironment, upregulation of anti-cancer immune cells, and suppression of the pro-cancer immune cells, associating with better survival of the breast cancer patients.
APA, Harvard, Vancouver, ISO, and other styles
28

Biagioli, Michele, Daniela Capobianco, Adriana Carino, Silvia Marchianò, Chiara Fiorucci, Patrizia Ricci, Eleonora Distrutti, and Stefano Fiorucci. "Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties." Nutrients 11, no. 2 (February 2, 2019): 325. http://dx.doi.org/10.3390/nu11020325.

Full text
Abstract:
A growing body of evidence suggests that probiotic functionality is not accurately predicted by their taxonomy. Here, we have set up a study to investigate the effectiveness of two probiotic formulations containing a blend of seven bacterial species in modulating intestinal inflammation in two rodent models of colitis, induced by treating mice with 2,4,6-Trinitrobenzenesulfonic acid (TNBS) or dextran sodium sulfate (DSS). Despite the taxonomy of the bacterial species in the two probiotic formulations being similar, only one preparation (Blend 2-Vivomixx) effectively attenuated the development of colitis in both models. In the TNBS model of colitis, Blend 2 reduced the expression of pro-inflammatory genes while increasing the production of anti-inflammatory cytokines, promoting the expansion M2 macrophages and the formation of IL-10-producing Treg cells in the colon’s lamina propria. In the DSS model of colitis, disease attenuation and Treg formation was observed only in mice administered with Blend 2, and this effect was associated with intestinal microbiota remodeling and increased formation of lactate, butyrate, and propionate. None of these effects were observed in mice administered with Blend 1 (VSL#3). In summary, we have shown that two probiotic mixtures obtained by combining taxonomically similar species produced with different manufacturing methods exert divergent effects in mouse models of colitis.
APA, Harvard, Vancouver, ISO, and other styles
29

Kurata, Ikuko, Maya Umekita, Tsutomu Sawa, Seiko Hattori, Chigusa Hayashi, Naoko Kinoshita, Yoshiko Homma, et al. "Paleic acid, a fatty acid from Paenibacillus sp.: taxonomy, fermentation, isolation, structure determination, and anti-Mannheimia and -Pasteurella activity." Journal of Antibiotics 63, no. 8 (July 28, 2010): 519–23. http://dx.doi.org/10.1038/ja.2010.90.

Full text
APA, Harvard, Vancouver, ISO, and other styles
30

KARWOWSKI, J. P., M. JACKSON, R. J. THERIAULT, R. H. CHEN, G. J. BARLOW, and M. L. MAUS. "Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. I. Taxonomy of the producing organism and fermentation." Journal of Antibiotics 42, no. 4 (1989): 506–11. http://dx.doi.org/10.7164/antibiotics.42.506.

Full text
APA, Harvard, Vancouver, ISO, and other styles
31

Nakao, Masafumi, Ken-ichiro Miyagawa, Yoshitaka Nakano, Takeshi Sakane, Mayumi Tada, Osamu Nishimura, and Masahiko Fujino. "ChemInform Abstract: Pyloricidins, Novel anti-Helicobacter pylori Antibiotics Produced by Bacillus sp. Part 1. Taxonomy, Fermentation, and Biological Activity." ChemInform 33, no. 21 (May 21, 2010): no. http://dx.doi.org/10.1002/chin.200221184.

Full text
APA, Harvard, Vancouver, ISO, and other styles
32

El Mihyaoui, Amina, Joaquim C. G. Esteves da Silva, Saoulajan Charfi, María Emilia Candela Castillo, Ahmed Lamarti, and Marino B. Arnao. "Chamomile (Matricaria chamomilla L.): A Review of Ethnomedicinal Use, Phytochemistry and Pharmacological Uses." Life 12, no. 4 (March 25, 2022): 479. http://dx.doi.org/10.3390/life12040479.

Full text
Abstract:
Matricaria chamomilla L. is a famous medicinal plant distributed worldwide. It is widely used in traditional medicine to treat all kinds of diseases, including infections, neuropsychiatric, respiratory, gastrointestinal, and liver disorders. It is also used as a sedative, antispasmodic, antiseptic, and antiemetic. In this review, reports on M. chamomilla taxonomy, botanical and ecology description, ethnomedicinal uses, phytochemistry, biological and pharmacological properties, possible application in different industries, and encapsulation were critically gathered and summarized. Scientific search engines such as Web of Science, PubMed, Wiley Online, SpringerLink, ScienceDirect, Scopus, and Google Scholar were used to gather data on M. chamomilla. The phytochemistry composition of essential oils and extracts of M. chamomilla has been widely analyzed, showing that the plant contains over 120 constituents. Essential oils are generally composed of terpenoids, such as α-bisabolol and its oxides A and B, bisabolone oxide A, chamazulene, and β-farnesene, among other compounds. On the other hand, M. chamomilla extracts were dominated by phenolic compounds, including phenolic acids, flavonoids, and coumarins. In addition, M. chamomilla demonstrated several biological properties such as antioxidant, antibacterial, antifungal, anti-parasitic, insecticidal, anti-diabetic, anti-cancer, and anti-inflammatory effects. These activities allow the application of M. chamomilla in the medicinal and veterinary field, food preservation, phytosanitary control, and as a surfactant and anti-corrosive agent. Finally, the encapsulation of M. chamomilla essential oils or extracts allows the enhancement of its biological activities and improvement of its applications. According to the findings, the pharmacological activities of M. chamomilla confirm its traditional uses. Indeed, M. chamomilla essential oils and extracts showed interesting antioxidant, antibacterial, antifungal, anticancer, antidiabetic, antiparasitic, anti-inflammatory, anti-depressant, anti-pyretic, anti-allergic, and analgesic activities. Moreover, the most important application of M. chamomilla was in the medicinal field on animals and humans.
APA, Harvard, Vancouver, ISO, and other styles
33

Webb, Darren. "Exploring the Relationship between Hope and Utopia: Towards a Conceptual Framework." Politics 28, no. 3 (October 2008): 197–206. http://dx.doi.org/10.1111/j.1467-9256.2008.00329.x.

Full text
Abstract:
This article outlines a framework for exploring the relationship between hope and utopia. Hope is conceptualised as a socially mediated human capacity that can be experienced in different modes. A taxonomy of modes of hoping is presented. This differentiates between non-utopian (‘estimative’ and ‘resolute’), anti-utopian (‘patient’) and utopian (‘critical’ and ‘transformative’) modes of hoping. When critical or transformative hope predominates within the collective emotional orientation of a society, it is suggested that utopian ideas are likely to thrive both as a product and a source of hope. A contemporary utopian politics thus requires the institutions of social life to be reconstituted so that they once again foster critical and transformative hope.
APA, Harvard, Vancouver, ISO, and other styles
34

Skarbek-Kazanecki, Jan. "Philosophy as a Mockery of Truth: Humour in Plato’s Charmides." Tekstualia 4, no. 59 (December 20, 2019): 3–26. http://dx.doi.org/10.5604/01.3001.0013.6434.

Full text
Abstract:
The article subsequently analyzes the examples of Socratic wit so as to illustrate selected functions of humour in Charmides, using the methodological framework based on the „taxonomy of wit” proposed by D.L. Long and A.C. Graesser (1988). Special attention has been paid to the prologue and to the myth about the Thracian magical incantation (epōidḗ) which Socrates learned from the physician and priest Zalmoxis. In the light of Socratic considerations of the human cognitive limits and the transmissibility of philosophy and knowledge, some forms of Socrates’ humour acquire an anti-dogmatic character; humour in Charmides is an expression of the philosophical inquiry and practice which involves the realization and acceptance of the human limits of knowledge.
APA, Harvard, Vancouver, ISO, and other styles
35

Delgado-Tiburcio, Eugenia Elisa, Jorge Cadena-Iñiguez, Edelmiro Santiago-Osorio, Lucero del Mar Ruiz-Posadas, Israel Castillo-Juárez, Itzen Aguiñiga-Sánchez, and Marcos Soto-Hernández. "Pharmacokinetics and Biological Activity of Cucurbitacins." Pharmaceuticals 15, no. 11 (October 26, 2022): 1325. http://dx.doi.org/10.3390/ph15111325.

Full text
Abstract:
Cucurbitacins are a class of secondary metabolites initially isolated from the Cucurbitaceae family. They are important for their analgesic, anti-inflammatory, antimicrobial, antiviral, and anticancer biological actions. This review addresses pharmacokinetic parameters recently reported, including absorption, metabolism, distribution, and elimination phases of cucurbitacins. It includes recent studies of the molecular mechanisms of the biological activity of the most studied cucurbitacins and some derivatives, especially their anticancer capacity, to propose the integration of the pharmacokinetic profiles of cucurbitacins and the possibilities of their use. The main botanical genera and species of American origin that have been studied, and others whose chemo taxonomy makes them essential sources for the extraction of these metabolites, are summarized.
APA, Harvard, Vancouver, ISO, and other styles
36

Argentiero, Antonella, Antonio Giovanni Solimando, Markus Krebs, Patrizia Leone, Nicola Susca, Oronzo Brunetti, Vito Racanelli, Angelo Vacca, and Nicola Silvestris. "Anti-angiogenesis and Immunotherapy: Novel Paradigms to Envision Tailored Approaches in Renal Cell-Carcinoma." Journal of Clinical Medicine 9, no. 5 (May 24, 2020): 1594. http://dx.doi.org/10.3390/jcm9051594.

Full text
Abstract:
Although decision making strategy based on clinico-histopathological criteria is well established, renal cell carcinoma (RCC) represents a spectrum of biological ecosystems characterized by distinct genetic and molecular alterations, diverse clinical courses and potential specific therapeutic vulnerabilities. Given the plethora of drugs available, the subtype-tailored treatment to RCC subtype holds the potential to improve patient outcome, shrinking treatment-related morbidity and cost. The emerging knowledge of the molecular taxonomy of RCC is evolving, whilst the antiangiogenic and immunotherapy landscape maintains and reinforces their potential. Although several prognostic factors of survival in patients with RCC have been described, no reliable predictive biomarkers of treatment individual sensitivity or resistance have been identified. In this review, we summarize the available evidence able to prompt more precise and individualized patient selection in well-designed clinical trials, covering the unmet need of medical choices in the era of next-generation anti-angiogenesis and immunotherapy.
APA, Harvard, Vancouver, ISO, and other styles
37

Raheem, Enas A., Sharifah Mumtazah Syed Ahmad, and Wan Azizun Wan Adnan. "Insight on face liveness detection: A systematic literature review." International Journal of Electrical and Computer Engineering (IJECE) 9, no. 6 (December 1, 2019): 5865. http://dx.doi.org/10.11591/ijece.v9i6.pp5865-5175.

Full text
Abstract:
<p>To review researcher’s attempts in response to the problem of spoofing and liveness detection, mapping the research overview from the literature survey into a suitable taxonomy, exploring the basic properties of the field, motivation of using liveness detection methods in face recognition, and Problems that may restrain the advantages. We presented a subjected search on face recognition with liveness detection and its synonyms in four main databases: Web of science, Science Direct, Scopus and IEEE Xplore. We believe that these databases are widely inclusive enough to cover the literature.<em> </em>The final number of articles considered is 65 articles. 4 of them where review and survey articles that described a general overview about liveness detection and anti-spoofing methods. Since 2012, and despite of leaving some areas unestablished and needs more attention, researchers tried to keep track of liveness detection in several ways. No matter what their category is, articles concentrated on challenges that faces the full utility of anti-spoofing methods and recommended some solutions to overcome these challenges. In this paper, different types of liveness detection and face anti-spoofing techniques are investigated to keep researchers updated with what is being developed in this field.</p>
APA, Harvard, Vancouver, ISO, and other styles
38

A. Zampetakis, Leonidas. "The emotional dimension of the consumption of luxury counterfeit goods: an empirical taxonomy." Marketing Intelligence & Planning 32, no. 1 (January 28, 2014): 21–40. http://dx.doi.org/10.1108/mip-10-2012-0102.

Full text
Abstract:
Purpose – The purpose of this paper is to develop a consumer taxonomy based on experienced emotions during non-deceptive counterfeit consumption situations, which could be useful for public policy makers, marketers, and anti-counterfeiting service providers trying to devise strategies so as to inhibit the problem of counterfeit consumption. Design/methodology/approach – The paper is based on a questionnaire survey/analysis of a sample of 312 randomly selected consumers. Surveys were administrated individually to consumers, through personal contact by the study authors. Data analysis was conducted in three steps: first, descriptive analyses; second, analysis of variance; and third, hierarchical cluster analysis. Findings – Results suggest that during non-deceptive counterfeit consumption situations, consumers experience complex emotions including both positive and negative affect. Furthermore, four different subgroups of consumers experienced relative specific but different emotional reactions. Research limitations/implications – The reported research relied on self-reports and on a sample from Greek consumers. Moreover, data were cross-sectional and alternatives relationships may exist. Future research should be multinational and longitudinal to test the assumptions of the present study and should encompass variables of actual emotions felt during non-deceptive counterfeit consumption situations. Practical implications – Results suggested that four different subgroups of consumers experienced relative specific but different emotional reactions. As a result, the study may help marketers and anti-counterfeiting service providers to establish more refined and more effective marketing strategies. Originality/value – Results of the present research are original and unique and provide new insights for marketing managers in their efforts to decrease counterfeit consumption of their products.
APA, Harvard, Vancouver, ISO, and other styles
39

Mukhopadhyay, Utpal K., Chetan C. Oturkar, Christina Adams, Nadi Wickramasekera, Sanjay Bansal, Rajesh Medisetty, Austin Miller, et al. "TP53 Status as a Determinant of Pro- vs Anti-Tumorigenic Effects of Estrogen Receptor-Beta in Breast Cancer." JNCI: Journal of the National Cancer Institute 111, no. 11 (April 16, 2019): 1202–15. http://dx.doi.org/10.1093/jnci/djz051.

Full text
Abstract:
Abstract Background Anti-tumorigenic vs pro-tumorigenic roles of estrogen receptor-beta (ESR2) in breast cancer remain unsettled. We investigated the potential of TP53 status to be a determinant of the bi-faceted role of ESR2 and associated therapeutic implications for triple negative breast cancer (TNBC). Methods ESR2-TP53 interaction was analyzed with multiple assays including the in situ proximity ligation assay. Transcriptional effects on TP53-target genes and cell proliferation in response to knocking down or overexpressing ESR2 were determined. Patient survival according to ESR2 expression levels and TP53 mutation status was analyzed in the basal-like TNBC subgroup in the Molecular Taxonomy of Breast Cancer International Consortium (n = 308) and Roswell Park Comprehensive Cancer Center (n = 46) patient cohorts by univariate Cox regression and log-rank test. All statistical tests are two-sided. Results ESR2 interaction with wild-type and mutant TP53 caused pro-proliferative and anti-proliferative effects, respectively. Depleting ESR2 in cells expressing wild-type TP53 resulted in increased expression of TP53-target genes CDKN1A (control group mean [SD] = 1 [0.13] vs ESR2 depletion group mean [SD] = 2.08 [0.24], P = .003) and BBC3 (control group mean [SD] = 1 [0.06] vs ESR2 depleted group mean [SD] = 1.92 [0.25], P = .003); however, expression of CDKN1A (control group mean [SD] = 1 [0.21] vs ESR2 depleted group mean [SD] = 0.56 [0.12], P = .02) and BBC3 (control group mean [SD] = 1 [0.03] vs ESR2 depleted group mean [SD] = 0.55 [0.09], P = .008) was decreased in cells expressing mutant TP53. Overexpressing ESR2 had opposite effects. Tamoxifen increased ESR2-mutant TP53 interaction, leading to reactivation of TP73 and apoptosis. High levels of ESR2 expression in mutant TP53-expressing basal-like tumors is associated with better prognosis (Molecular Taxonomy of Breast Cancer International Consortium cohort: log-rank P = .001; hazard ratio = 0.26, 95% confidence interval = 0.08 to 0.84, univariate Cox P = .02). Conclusions TP53 status is a determinant of the functional duality of ESR2. Our study suggests that ESR2-mutant TP53 combination prognosticates survival in TNBC revealing a novel strategy to stratify TNBC for therapeutic intervention potentially by repurposing tamoxifen.
APA, Harvard, Vancouver, ISO, and other styles
40

Arora, Bharti, Preeti Bhadauria, Deepak Tripathi, and Alok Sharma. "Sapindus emarginatus: Phytochemistry & Various Biological Activities." Indo Global Journal of Pharmaceutical Sciences 02, no. 03 (2012): 250–57. http://dx.doi.org/10.35652/igjps.2012.31.

Full text
Abstract:
Sapindus emarginatus is important indigenous plant with lots of traditional importance belongs to family sapindaceae. It is commonly called as Soap nut tree which is found in most of the hilly regions of India. Each and every part of the plant is used traditionally in various ailments. Trees of genus Sapindus are cultivated in many parts of India. The secondary metabolites present in Sapindus emarginatus were found to be alkaloids, carbohydrates, phenols, flavonoids, saponins fixed oils & fats. It possesses various activities such as surfactant, mild detergent, anti-inflammatory, antipruritic, antihyperlipidemic, antimicrobial, CNS, emetic, hair tonic, nasal insufflations. Therefore the aim of the present review is to summarize the taxonomy, chemical constituents and various studies on the biological activities of the plant Sapindus emarginatus. © 2011 IGJPS. All rights reserved.
APA, Harvard, Vancouver, ISO, and other styles
41

TAKEUCHI, HITOSHI, NAOKI ASAI, KAZUNORI TANABE, TERUYA KOZAKI, MASANORI FUJITA, TAKASHI SAKAI, AKIFUMI OKUDA, et al. "EM2487, a Novel Anti-HIV-1 Antibiotic, Produced by Streptomyces sp. Mer-2487. Taxonomy, Fermentation, Biological Properties, Isolation and Structure Elucidation." Journal of Antibiotics 52, no. 11 (1999): 971–82. http://dx.doi.org/10.7164/antibiotics.52.971.

Full text
APA, Harvard, Vancouver, ISO, and other styles
42

Watanabe, Takumi, and et al et al. "ChemInform Abstract: Paleic Acid, a Fatty Acid from Paenibacillus sp.; Taxonomy, Fermentation, Isolation, Structure Determination, and anti-Mannheimia and -Pasteurella Activity." ChemInform 41, no. 51 (November 26, 2010): no. http://dx.doi.org/10.1002/chin.201051209.

Full text
APA, Harvard, Vancouver, ISO, and other styles
43

Chandran, P., S. K. Ray, T. Bhattacharyya, P. Srivastava, P. Krishnan, and D. K. Pal. "Lateritic soils of Kerala, India: their mineralogy, genesis, and taxonomy." Soil Research 43, no. 7 (2005): 839. http://dx.doi.org/10.1071/sr04128.

Full text
Abstract:
In this study, we report the chemical and mineralogical characteristics of 4 benchmark Ultisols of Kerala to elucidate their genesis and taxonomy. The taxonomic rationale of the mineralogy class of Ultisols and other highly weathered soils on the basis of the contemporary pedogenesis is also explained. The Ultisols of Kerala have low pH, low cation exchange capacity, low effective cation exchange capacity and base saturation, with dominant presence of 1 : 1 clays and gibbsite. Presence of gibbsite along with 2 : 1 minerals discounts the hypothesis of anti-gibbsite effect. Since the kaolins are interstratified with hydroxy-interlayered vermiculites (HIV), the formation of gibbsite from kaolinite is not tenable. Thus, gibbsite is formed from primary minerals in an earlier alkaline pedo-environment. Therefore, the presence of gibbsite does not necessarily indicate an advanced stage of weathering. On the basis of a dominant amount of gibbsite, a mineralogy class such as allitic or gibbsitic does not establish a legacy between the contemporary pedogenesis and the mineralogy. The dominance of kaolin–HIV in the fine clays of Ultisols and their persistence, possibly since early Tertiary, suggests that ‘steady state’ may exist in soils developed on long-term weathered saprolite. Since the present acid environment of Ultisols does not allow desilication, the chemical transformation of Ultisols to Oxisols with time is difficult to reconcile as envisaged in the traditional model of tropical soil genesis.
APA, Harvard, Vancouver, ISO, and other styles
44

Khairullah, Aswin Rafif, Tridiganita Intan Solikhah, Arif Nur Muhammad Ansori, and Hartanto Mulyo Raharjo. "A review on phytochemistry and pharmacology of Eclipta alba L.: A valuable medicinal plant." Research Journal of Biotechnology 17, no. 3 (February 25, 2022): 134–39. http://dx.doi.org/10.25303/1703rjbt134139.

Full text
Abstract:
Eclipta alba L. is a medicinal plant included in the Asteraceae family. This plant is generally called as false daisy and bhringaraj. In traditional medicine, this plant is utilized to medicate various diseases in humans such as diabetes, coronary heart disease, gastrointestinal disease, skin disease, vitiligo, skin lesions, respiratory diseases and high blood pressure. Additionally, Eclipta alba has been widely utilized as a hair grower and dye. Eclipta alba contains various active compounds such as glycosides, triterpenoids, alkaloids, flavonoids, coumestans and polyacetyl. This plant is believed to have several pharmacological activities such as antibacterial, antifungal, anthelmintic, antimalarial, hepatoprotective, neuroprotective, immunomodulatory, analgesic, diuretic, hypolipidemic, anti-inflammatory, antidiabetic, antioxidant, anticancer, hair growth promoting, memory enhancing and antivenom. The aim of this review as discussions on the taxonomy, plant description, geographical distribution, phytochemistry, traditional use, medicinal value, pharmacological activity of the Eclipta alba L.
APA, Harvard, Vancouver, ISO, and other styles
45

Björnberg, Karin Edvardsson, Helena Röcklinsberg, and Per Sandin. "'Cornwallism' and Arguments against Greenhouse Gas Emissions Reductions." Environmental Values 29, no. 6 (December 1, 2020): 691–711. http://dx.doi.org/10.3197/096327119x15579936382554.

Full text
Abstract:
Opposition against greenhouse gas emissions reductions is strong among some conservative Christian groups, especially in the United States. In this paper, we identify five scripture-based arguments against greenhouse gas mitigation put forward by a core group of Christian conservatives ('the Cornwallists'): the anti-paganism argument, the enrichment argument, the omnipotence argument, the lack of moral relevance argument and the cost-benefit argument. We evaluate to what extent the arguments express positions that can be characterised as climate science denialist and to what degree they are consistent with support for climate adaptation. Using Stefan Rahmstorf's (2004) taxonomy of climate science denial, we conclude that the Cornwallists could be labelled climate change deniers. However, their opposition is not only based on denial of climate science but often rests on premises that render the science irrelevant, a position we term 'relevance denialism'.
APA, Harvard, Vancouver, ISO, and other styles
46

Samoylov, Mikhail Ivanovich, Aleksandr Sergeevich Pankov, Darya Aleksandrovna Kuzmina, and Elena Mikhaylovna Kryukova. "Prevention of new coronavirus infection (COVID-19) in a specialized psychiatric hospital." Disinfection affairs, no. 1 (March 2022): 45–49. http://dx.doi.org/10.35411/2076-457x-2022-1-45-49.

Full text
Abstract:
At the end of 2019, an outbreak of a new coronavirus infection occurred in the People’s Republic of China (PRC), with its epicenter in the city of Wuhan (Hubei Province). The World Health Organization (WHO) has defined the official name of the infection caused by the novel coronavirus as Coronavirus disease 2019 («COVID-19») [4]. The International Committee on the Taxonomy of Viruses assigned the official name of the causative agent of infection – SARS-CoV-2 [3]. In accordance with the sanitary legislation of the Russian Federation, the virus is assigned to pathogenicity group II [5]. COVID-19 occurs in two main forms that are subject to registration as independent nosological units: clinically pronounced – (U07.1) and carriage of the causative agent of coronavirus infection – (Z22.8) [4]. All forms of manifestations of coronavirus infection are dangerous, but the asymptomatic form poses the greatest epidemiological danger, due to the difficulty of detection and, as a result, the untimely implementation of anti-epidemic measures [2]. The role of COVID-19 as a healthcare-associated infection has been established [3]. Sysin E.I. and co-authors established the maximum values of the foci index (IO) for nosocomial spread of COVID-19 in psychiatric hospitals [9]. The inclusion of COVID-19 in the «List of diseases that pose a danger to others» [7] determines the epidemic significance of the disease. Keywords: new coronavirus infection, anti-epidemic regime, psychiatric hospital, quality of anti-epidemic regime.
APA, Harvard, Vancouver, ISO, and other styles
47

von Martels, Julius Z. H., Arno R. Bourgonje, Marjolein A. Y. Klaassen, Hassan A. A. Alkhalifah, Mehdi Sadaghian Sadabad, Arnau Vich Vila, Ranko Gacesa, et al. "Riboflavin Supplementation in Patients with Crohn’s Disease [the RISE-UP study]." Journal of Crohn's and Colitis 14, no. 5 (December 24, 2019): 595–607. http://dx.doi.org/10.1093/ecco-jcc/jjz208.

Full text
Abstract:
Abstract Background and Aims Crohn’s disease [CD] is characterised by chronic intestinal inflammation and dysbiosis in the gut. Riboflavin [vitamin B2] has anti-inflammatory, antioxidant and microbiome-modulatory properties. Here, we analysed the effect of riboflavin on oxidative stress, markers of inflammation, clinical symptoms, and faecal microbiome in patients with CD. Methods In this prospective clinical intervention study, patients received 100 mg riboflavin [DSM, Nutritional Products Ltd] daily for 3 weeks. Clinical disease activity [Harvey-Bradshaw Index: HBI], serum biomarkers of inflammation and redox status [plasma free thiols], and faecal microbiome taxonomical composition and functionality [fluorescent in situ hybridisation: FISH; and metagenomic shotgun sequencing: MGS], were analysed before and after riboflavin intervention. Results In total, 70 patients with CD with varying disease activity were included. Riboflavin supplementation significantly decreased serum levels of inflammatory markers. In patients with low faecal calprotectin [FC] levels, IL-2 decreased, and in patients with high FC levels, C-reactive protein [CRP] was reduced and free thiols significantly increased after supplementation. Moreover, HBI was significantly decreased by riboflavin supplementation. Riboflavin supplementation led to decreased Enterobacteriaceae in patients with low FC levels as determined by FISH; however, MGS analysis showed no effects on diversity, taxonomy, or metabolic pathways of the faecal microbiome. Conclusions Three weeks of riboflavin supplementation resulted in a reduction in systemic oxidative stress, mixed anti-inflammatory effects, and a reduction in clinical symptoms [HBI]. FISH analysis showed decreased Enterobacteriaceae in patients with CD with low FC levels, though this was not observed in MGS analysis. Our data demonstrate that riboflavin supplementation has a number of anti-inflammatory and anti-oxidant effects in CD.
APA, Harvard, Vancouver, ISO, and other styles
48

NISHIHARA, YUTAKA, EISAKU TSUJII, YUKIKO YAMAGISHI, KAZUTOSHI SAKAMOTO, YASUHISA TSURUMI, SHIGETADA FURUKAWA, REIKO OHTSU, et al. "FR198248, a New Anti-influenza Agent Isolated from Aspergillus terreus No.13830. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities." Journal of Antibiotics 54, no. 2 (2001): 136–43. http://dx.doi.org/10.7164/antibiotics.54.136.

Full text
APA, Harvard, Vancouver, ISO, and other styles
49

He, Rui-Jie, Ya-Feng Wang, Bing-Yuan Yang, Zhang-Bin Liu, Dian-Peng Li, Bi-Qun Zou, and Yong-Lin Huang. "Structural Characterization and Assessment of Anti-Inflammatory Activities of Polyphenols and Depsidone Derivatives from Melastoma malabathricum subsp. normale." Molecules 27, no. 5 (February 24, 2022): 1521. http://dx.doi.org/10.3390/molecules27051521.

Full text
Abstract:
The roots of Melastoma malabathricum subsp. normale (D. Don) Karst. Mey have been used in traditional ethnic medicine systems in China to treat inflammation-triggered ailments, such as trauma, toothache, and fever. Therefore, the aim of this study is to screen for compounds with anti-inflammatory activity in the title plant. The extract of M. malabathricum subsp. normale roots was separated using various chromatographic methods, such as silica gel, ODS C18, MCI gel, and Sephadex LH-20 column chromatography, as well as semi-preparative HPLC. One new complex tannin, named whiskey tannin D (1), and an undescribed tetracyclic depsidone derivative, named guanxidone B (2), along with nine known polyphenols (2–10) and three known depsidone derivatives (12–14) were obtained from this plant. The structures of all compounds were elucidated by extensive NMR and CD experiments in conjunction with HR-ESI-MS data. All these compounds were isolated from this plant for the first time. Moreover, compounds 1–4, 8, and 10–14 were obtained for the first time from the genus Melastoma, and compounds 1, 2, and 11–14 have not been reported from the family Melastomataceae. This is the first report of complex tannin and depsidone derivatives from M. malabathricum subsp. normale, indicating their chemotaxonomic significance to this plant. Compounds 1–12 were investigated for their anti-inflammatory activities on the production of the nitric oxide (NO) in lipopolysaccharide (LPS)-stimulated RAW264.7 cells, and compounds 1, 11, and 12 showed anti-inflammatory activities with IC50 values of 6.46 ± 0.23 µM, 8.02 ± 0.35 µM, and 9.82 ± 0.43 µM, respectively. The structure–activity relationship showed that the catechin at glucose C-1 in ellagitannin was the key to its anti-inflammatory activity, while CH3O- at C-16 of aromatic ring A in depsidone derivatives had little effect on its anti-inflammatory activity. The study of structure–activity relationships is helpful to quickly discover new anti-inflammatory drugs. The successful isolation and structure identification of these compounds, especially complex tannin 1, not only provide materials for the screening of anti-inflammatory compounds, but also provide a basis for the study of chemical taxonomy of the genus Melastoma.
APA, Harvard, Vancouver, ISO, and other styles
50

Wei, Chen, Florenly Florenly, Dewi Riastawaty Purba, and Fioni Fioni. "The Healing Analysis of II Degree Burn from Surgery Essential Oil Ointment (Curcuma Longa) in Wistar Rats (Rattus Norvegicus)." Budapest International Research in Exact Sciences (BirEx) Journal 4, no. 1 (December 20, 2021): 31–42. http://dx.doi.org/10.33258/birex.v4i1.3474.

Full text
Abstract:
Data in Indonesia the death rate from burns is still high at around 40%, mainly caused by severe burns. The most potential medicinal turmeric plant is its rhizome, which contains the phenolic compound curcumin and essential oils. Some of the benefits of turmeric antioxidants, anti-inflammatory, anti-cancer, acetylcholinesterase activity inhibitors, anti-fungal, and anti-bacterial. This study aims to find out the phytochemical content and effects of Turmeric Essential Oil Ointment (Curcuma longa Linn) in curing grade II burns in Wistar rats (Rattus norvegicus). This type of research is experimental with a pre-post approach and post-test control group design. The study was conducted at Riwandi Pet Shop and Animal House March-May 2021. The research sample is turmeric (Curcuma longa) obtained from a traditional market in the city of Medan and identified in herbarium Medanese (MEDA), Laboratoirum Taxonomy of Plants, Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), University of North Sumatra, Medan. The test animal is a Wistar strain rat with as many as 20 tails divided into 4 treatment groups, so each group consists of 5 rats. The results of the study contained significant differences in the epithelial period of the standard group, 10% turmeric ointment and 15% against the control group. However, in the turmeric ointment group and the standard group, there was no difference in epithelialization periods. This is evident from the value P < 0.05 (Value P = 0.029). The healing effects of burns possessed by Turmeric ointment are both 10% and 15% and nebacetin ointment as standard shows significant differences. Where the wound contraction rate of turmeric ointment is 15% better than nebacetin ointment as standard. But in both turmeric ointments, both 10% and 15% and nebacetin ointment as standard did not show significant differences in the parameters of the epithelial period.
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography