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Journal articles on the topic 'Anti-inflammatory agents'

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Published: 4 June 2021
Last updated: 29 July 2024

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1

Davis, L. "Ocean Anti-Inflammatory Agents." Science News 130, no. 11 (September 13, 1986): 164. http://dx.doi.org/10.2307/3971034.

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2

Mohamed, Mosaad S., Aymn E. Rashad, Mostafa Adbel-Monem, and Samar S. Fatahalla. "New Anti-Inflammatory Agents." Zeitschrift für Naturforschung C 62, no. 1-2 (February 1, 2007): 27–31. http://dx.doi.org/10.1515/znc-2007-1-205.

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The pyrrole derivatives 1a, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to the standard drug indomethacin.
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3

KAWAI, SHIN'ICHI. "Trends of development of anti-inflammatory agents. Antisense therapy as anti-inflammatory agents." Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 28, no. 1 (1997): 73–74. http://dx.doi.org/10.3999/jscpt.28.73.

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4

Lehra, K. S., S. Goyal, B. S. Bajwa, R. Kaur, and S. Singh. "ANTI-INFLAMMATORY AGENTS FROM PLANTS." INDIAN DRUGS 49, no. 04 (April 28, 2012): 5–11. http://dx.doi.org/10.53879/id.49.04.p0005.

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Most of the available non-steroidal anti-inflammatory drugs are devoid of gastro protective property.Therefore, the search for new anti-inflammatory agents from the huge array of medicinal plant resources is intensifying. Guggul sterones, boswellic acid, curcumin, withaferin-A and and rographolide have been reported to be promising anti-inflammatory agents in animal models. Scientists are of the view that there is acute shortage of leads for developing anti-inflammatory drugs. We need to initiate pending work on these phyto-constituents with emphasis on side effect profile. This paper provides an overview on the recent findings of some plants having anti-inflammatory activity and chemical constituents isolated from them.
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5

Avti, Pramod K., and Ashok Kakkar. "Dendrimers as anti-inflammatory agents." Brazilian Journal of Pharmaceutical Sciences 49, spe (2013): 57–65. http://dx.doi.org/10.1590/s1984-82502013000700006.

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Dendrimers constitute an intriguing class of macromolecules which find applications in a variety of areas including biology. These hyperbranched macromolecules with tailored backbone and surface groups have been extensively investigated as nanocarriers for gene and drug delivery, by molecular encapsulation or covalent conjugation. Dendrimers have provided an excellent platform to develop multivalent and multifunctional nanoconjugates incorporating a variety of functional groups including drugs which are known to be anti-inflammatory agents. Recently, dendrimers have been shown to possess anti-inflammatory properties themselves. This unexpected and intriguing discovery has provided an additional impetus in designing novel active pharmaceutical agents. In this review, we highlight some of the recent developments in the field of dendrimers as nanoscale anti-inflammatory agents.
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6

Tsicopoulos, A., and P. de Nadai. "Antihistamines as anti-inflammatory agents." Clinical & Experimental Allergy 33, no. 11 (November 2003): 1476–78. http://dx.doi.org/10.1046/j.1365-2222.2003.01802.x.

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7

Nuutinen, LS. "Non-steroidal anti-inflammatory agents." Acta Anaesthesiologica Scandinavica 37 (December 1993): 124–25. http://dx.doi.org/10.1111/j.1399-6576.1993.tb03655.x.

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8

Flanagan, Thomas W., and Charles D. Nichols. "Psychedelics as anti-inflammatory agents." International Review of Psychiatry 30, no. 4 (July 4, 2018): 363–75. http://dx.doi.org/10.1080/09540261.2018.1481827.

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9

Vader, L. "Non steroidal anti-inflammatory agents." Insight - the Journal of the American Society of Ophthalmic Registered Nurses 25, no. 1 (March 2000): 20–21. http://dx.doi.org/10.1016/s1060-135x(00)90036-8.

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10

Serafini, Mauro, Ilaria Peluso, and Anna Raguzzini. "Flavonoids as anti-inflammatory agents." Proceedings of the Nutrition Society 69, no. 3 (June 23, 2010): 273–78. http://dx.doi.org/10.1017/s002966511000162x.

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Epidemiological evidence suggests that a high intake of plant foods is associated with lower risk of chronic diseases. However, the mechanism of action and the components involved in this effect have not been identified clearly. In recent years, the scientific community has agreed to focus its attention on a class of secondary metabolites extensively present in a wide range of plant foods: the flavonoids, suggested as having different biological roles. The anti-inflammatory actions of flavonoids in vitro or in cellular models involve the inhibition of the synthesis and activities of different pro-inflammatory mediators such as eicosanoids, cytokines, adhesion molecules and C-reactive protein. Molecular activities of flavonoids include inhibition of transcription factors such as NF-κB and activating protein-1 (AP-1), as well as activation of nuclear factor-erythroid 2-related factor 2 (Nrf2). However, the in vitro evidence might be somehow of limited impact due to the non-physiological concentrations utilized and to the fact that in vivo flavonoids are extensively metabolized to molecules with different chemical structures and activities compared with the ones originally present in the food. Human studies investigating the effect of flavonoids on markers of inflammation are insufficient, and are mainly focused on flavonoid-rich foods but not on pure molecules. Most of the studies lack assessment of flavonoid absorption or fail to associate an effect on inflammation with a change in circulating levels of flavonoids. Human trials with appropriate placebo and pure flavonoid molecules are needed to clarify if flavonoids represent ancillary ingredients or key molecules involved in the anti-inflammatory properties of plant foods.
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11

Weitz-Schmidt, Gabriele. "Statins as anti-inflammatory agents." Trends in Pharmacological Sciences 23, no. 10 (October 2002): 482–87. http://dx.doi.org/10.1016/s0165-6147(02)02077-1.

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12

&NA;. "PAR2 antagonists: anti-inflammatory agents?" Inpharma Weekly &NA;, no. 1226 (February 2000): 9. http://dx.doi.org/10.2165/00128413-200012260-00017.

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13

Kontogiorgis, C., and D. Hadjipavlou-Litina. "Non Steroidal Anti-Inflammatory and Anti-Allergy Agents." Current Medicinal Chemistry 9, no. 1 (January 1, 2002): 89–98. http://dx.doi.org/10.2174/0929867023371409.

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14

Ceriello, Antonio. "Thiazolidinediones as anti-inflammatory and anti-atherogenic agents." Diabetes/Metabolism Research and Reviews 24, no. 1 (2007): 14–26. http://dx.doi.org/10.1002/dmrr.790.

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15

Iarlori, Carla. "Anti-Inflammatory Agents in Parkinsons Disease." Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 8, no. 1 (March 1, 2009): 72–84. http://dx.doi.org/10.2174/187152309787580757.

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16

Leong, Keng Hong. "COX2 Inhibitors as Anti-Inflammatory Agents." Singapore Family Physicians 43, no. 1 (January 1, 2017): 19–20. http://dx.doi.org/10.33591/sfp.43.1.u4.

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17

Rayburn, Elizabeth. "Anti-Inflammatory Agents for Cancer Therapy." Molecular and Cellular Pharmacology 1, no. 1 (February 10, 2009): 29–43. http://dx.doi.org/10.4255/mcpharmacol.09.05.

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18

Mohammed, Mona S., Wadah J. A. Osman, Elrashied A. E. Garelnabi, Zuheir Osman, Bashier Osman, Hassan S. Khalid, and Magdi A. Mohamed. "Secondary metabolites as anti-inflammatory agents." Journal of Phytopharmacology 3, no. 4 (August 25, 2014): 275–85. http://dx.doi.org/10.31254/phyto.2014.3409.

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Inflammation is a complex pathophysiological process mediated by a variety of signaling molecules and can be classified as either acute or chronic. Anti inflammatory drugs are broadly classified into two categories: Steroidal and Non steroidal anti-inflammatory agents (NSAIDs) some of them are no longer used due to their severe adverse effects. Traditionally, people have been using powerful anti-inflammatory plants for thousands of years as part of their diet and pharmaceutical arsenal, and secondary compounds derived from these plants may offer important sources of anti-inflammatory agents.
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19

Chen, Wendy Y., and Jennifer A. Ligibel. "Anti-inflammatory Agents for Breast Cancer." JAMA Oncology 7, no. 9 (September 1, 2021): 1289. http://dx.doi.org/10.1001/jamaoncol.2021.2056.

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20

Sondhi, Sham, Monica Dinodia, Jaiveer Singh, and Reshma Rani. "Heterocyclic Compounds as Anti-Inflammatory Agents." Current Bioactive Compounds 3, no. 2 (June 1, 2007): 91–108. http://dx.doi.org/10.2174/157340707780809554.

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21

Liao, J. K. "Statins: potent vascular anti-inflammatory agents." International Journal of Clinical Practice 58 (September 27, 2004): 41–48. http://dx.doi.org/10.1111/j.1368-504x.2004.00375.x.

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22

Andrade, Chittaranjan. "Antidepressant Augmentation With Anti-Inflammatory Agents." Journal of Clinical Psychiatry 75, no. 09 (September 25, 2014): 975–77. http://dx.doi.org/10.4088/jcp.14f09432.

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23

Stewart, William K., and L. W. Fleming. "Perthshire Pioneer of Anti-Inflammatory Agents." Scottish Medical Journal 32, no. 5 (October 1987): 141–46. http://dx.doi.org/10.1177/003693308703200508.

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The achievements of Thomas John Maclagan (1838–1903) include the first specific use of salicin to cure acute articular rheumatism. He began salicin treatment in 1874 in Dundee, where he was a medical practitioner from 1869 to 1879. Maclagan was also the resident medical superintendent at Dundee Royal Infirmary from 1864–1866, where he was the first in Scotland to make investigative use of the clinical thermometer during the fever epidemics. From 1879–1903 he maintained a fashionable practice in London. His contributions to medicine and in particular to the development of aspirin, once ranked as equivalent to the achievements of Lister and Simpson, have now largely been forgotten. This account is a tribute to a life rich in individual endeavour, observation and effort before the “teamwork” era began.
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24

BONHAM, C. A., and A. W. THOMSON. "Anti-inflammatory agents in allergic diseases." Clinical & Experimental Immunology 102, no. 1 (June 28, 2008): 1–5. http://dx.doi.org/10.1111/j.1365-2249.1995.tb06627.x.

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25

Adcock, I. M. "HDAC inhibitors as anti-inflammatory agents." British Journal of Pharmacology 150, no. 7 (April 2007): 829–31. http://dx.doi.org/10.1038/sj.bjp.0707166.

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26

Morris, John L., David A. Rosen, and Kathleen R. Rosen. "Nonsteroidal Anti-Inflammatory Agents in Neonates." Pediatric Drugs 5, no. 6 (2003): 385–405. http://dx.doi.org/10.2165/00128072-200305060-00004.

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27

BRATER, D. "Anti-inflammatory agents and renal function☆, ☆☆." Seminars in Arthritis and Rheumatism 32, no. 3 (December 2002): 33–42. http://dx.doi.org/10.1053/sarh.2002.37216.

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28

Ostrow, Gregory, Bibiana Jin Reiser, Kamiar Mireskandari, and Nasrin Najm-Tehrani. "Anti-inflammatory agents in pediatric ophthalmology." Journal of American Association for Pediatric Ophthalmology and Strabismus 18, no. 4 (August 2014): e45. http://dx.doi.org/10.1016/j.jaapos.2014.07.145.

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29

White, Andrew A., and Ronald A. Simon. "Macrolide antibiotics as anti-inflammatory agents." Current Allergy and Asthma Reports 5, no. 1 (January 2005): 1–3. http://dx.doi.org/10.1007/s11882-005-0046-4.

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30

Chyatte, Douglas. "Anti-inflammatory Agents and Cerebral Vasospasm." Neurosurgery Clinics of North America 1, no. 2 (April 1990): 433–50. http://dx.doi.org/10.1016/s1042-3680(18)30817-9.

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31

Pande, Kalpana, Manju Tandon, Triloki N. Bhalla, Surendra S. Parmar, and Jayanti P. Barthwal. "Tetrazoles as Potent Anti-Inflammatory Agents." Pharmacology 35, no. 6 (1987): 333–38. http://dx.doi.org/10.1159/000138358.

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32

Zappavigna, Silvia, Alessia Maria Cossu, Anna Grimaldi, Marco Bocchetti, Giuseppe Andrea Ferraro, Giovanni Francesco Nicoletti, Rosanna Filosa, and Michele Caraglia. "Anti-Inflammatory Drugs as Anticancer Agents." International Journal of Molecular Sciences 21, no. 7 (April 9, 2020): 2605. http://dx.doi.org/10.3390/ijms21072605.

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Inflammation is strictly associated with cancer and plays a key role in tumor development and progression. Several epidemiological studies have demonstrated that inflammation can predispose to tumors, therefore targeting inflammation and the molecules involved in the inflammatory process could represent a good strategy for cancer prevention and therapy. In the past, several clinical studies have demonstrated that many anti-inflammatory agents, including non-steroidal anti-inflammatory drugs (NSAIDs), are able to interfere with the tumor microenvironment by reducing cell migration and increasing apoptosis and chemo-sensitivity. This review focuses on the link between inflammation and cancer by describing the anti-inflammatory agents used in cancer therapy, and their mechanisms of action, emphasizing the use of novel anti-inflammatory agents with significant anticancer activity.
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33

Fülöp, F., László Lázár, Z. Szakonyi, M. Pihlavisto, Sakari Alaranta, P. J. Vainio, Auni Juhakoski, Anne Marjamäki, and D. J. Smith. "Discovery of new anti-inflammatory agents." Pure and Applied Chemistry 76, no. 5 (January 1, 2004): 965–72. http://dx.doi.org/10.1351/pac200476050965.

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We have synthesized a series of novel hydrazines and hydrazino alcohols that specifically inhibit vascular adhesion protein-1 (VAP-1), a human endothelial cell adhesion molecule with a well documented role in inflammation. VAP-1 is a semicarbazide-sensitive amine oxidase (SSAO), and the enzyme activity has been demonstrated to have a role in VAP-1 function. An indane hydrazino alcohol was able to reduce clinical symptoms of inflammation in experimental arthritis in rodents and has the potential to be a novel anti-inflammatory drug.
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34

Xourgia, Eleni, Eleni-Margarita Tzouganatou, Athanasia Papazafiropoulou, and Andreas Melidonis. "Anti-inflammatory properties of antidiabetic agents." World Journal of Meta-Analysis 7, no. 4 (April 30, 2019): 129–41. http://dx.doi.org/10.13105/wjma.v7.i4.129.

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35

Ali, Mohamed Ehab, Jason T. McConville, and Alf Lamprecht. "Pulmonary delivery of anti-inflammatory agents." Expert Opinion on Drug Delivery 12, no. 6 (December 23, 2014): 929–45. http://dx.doi.org/10.1517/17425247.2015.993968.

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36

Dinarello, Charles A. "Anti-inflammatory Agents: Present and Future." Cell 140, no. 6 (March 2010): 935–50. http://dx.doi.org/10.1016/j.cell.2010.02.043.

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37

Aisen, Paul S. "Anti-inflammatory agents in Alzheimer’s disease." Current Neurology and Neuroscience Reports 2, no. 5 (October 2002): 405–9. http://dx.doi.org/10.1007/s11910-002-0066-6.

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38

Grahame, R. "TRANSDERMAL NON‐STEROIDAL ANTI‐INFLAMMATORY AGENTS." International Journal of Clinical Practice 49, no. 1 (January 1995): 33–35. http://dx.doi.org/10.1111/j.1742-1241.1995.tb09874.x.

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39

Scotti, Luciana, and Marcus T. Scotti. "Natural Products as Anti-Inflammatory Agents." Combinatorial Chemistry & High Throughput Screening 25, no. 14 (December 2022): 2315–16. http://dx.doi.org/10.2174/138620732514220908123932.

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40

Liu, Kung-Cheng, Jim-Min Fang, Jia-Tsrong Jan, Ting-Jen R. Cheng, Shi-Yun Wang, Shi-Ting Yang, Yih-Shyun E. Cheng, and Chi-Huey Wong. "Enhanced Anti-influenza Agents Conjugated with Anti-inflammatory Activity." Journal of Medicinal Chemistry 55, no. 19 (September 20, 2012): 8493–501. http://dx.doi.org/10.1021/jm3009844.

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41

Fry, Stephen W., and Leonard B. Seeff. "HEPATOTOXICITY OF ANALGESICS AND ANTI-INFLAMMATORY AGENTS." Gastroenterology Clinics of North America 24, no. 4 (December 1995): 875–905. http://dx.doi.org/10.1016/s0889-8553(21)00232-6.

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42

Bost, JeffreyW, Adara Maroon, and JosephC Maroon. "Natural anti-inflammatory agents for pain relief." Surgical Neurology International 1, no. 1 (2010): 80. http://dx.doi.org/10.4103/2152-7806.73804.

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43

Olkkola, Klaus T., Aurora V. Brunetto, and Mauri J. Mattila. "Pharmacokinetics of Oxicam Nonsteroidal Anti-Inflammatory Agents." Clinical Pharmacokinetics 26, no. 2 (February 1994): 107–20. http://dx.doi.org/10.2165/00003088-199426020-00004.

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44

Nunes, Clara dos Reis, Mariana Barreto Arantes, Silvia Menezes de Faria Pereira, Larissa Leandro da Cruz, Michel de Souza Passos, Luana Pereira de Moraes, Ivo José Curcino Vieira, and Daniela Barros de Oliveira. "Plants as Sources of Anti-Inflammatory Agents." Molecules 25, no. 16 (August 15, 2020): 3726. http://dx.doi.org/10.3390/molecules25163726.

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Plants represent the main source of molecules for the development of new drugs, which intensifies the interest of transnational industries in searching for substances obtained from plant sources, especially since the vast majority of species have not yet been studied chemically or biologically, particularly concerning anti-inflammatory action. Anti-inflammatory drugs can interfere in the pathophysiological process of inflammation, to minimize tissue damage and provide greater comfort to the patient. Therefore, it is important to note that due to the existence of a large number of species available for research, the successful development of new naturally occurring anti-inflammatory drugs depends mainly on a multidisciplinary effort to find new molecules. Although many review articles have been published in this regard, the majority presented the subject from a limited regional perspective. Thus, the current article presents highlights from the published literature on plants as sources of anti-inflammatory agents.
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45

Mantzanidou, Martha, Eleni Pontiki, and Dimitra Hadjipavlou-Litina. "Pyrazoles and Pyrazolines as Anti-Inflammatory Agents." Molecules 26, no. 11 (June 5, 2021): 3439. http://dx.doi.org/10.3390/molecules26113439.

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The five-membered heterocyclic group of pyrazoles/pyrazolines plays important role in drug discovery. Pyrazoles and pyrazolines present a wide range of biological activities. The synthesis of the pyrazolines and pyrazole derivatives was accomplished via the condensation of the appropriate substituted aldehydes and acetophenones, suitable chalcones and hydrazine hydrate in absolute ethanol in the presence of drops of glacial acetic acid. The compounds are obtained in good yields 68–99% and their structure was confirmed using IR, 1H-NMR, 13C-NMR and elemental analysis. The novel derivatives were studied in vitro for their antioxidant, anti-lipid peroxidation (AAPH) activities and inhibitory activity of lipoxygenase. Both classes strongly inhibit lipid peroxidation. Compound 2g was the most potent lipoxygenase inhibitor (IC50 = 80 µM). The inhibition of the carrageenin-induced paw edema (CPE) and nociception was also determined, with compounds 2d and 2e being the most potent. Compound 2e inhibited nociception higher than 2d. Pyrazoline 2d was found to be active in a preliminary test, for the investigation of anti-adjuvant-induced disease (AID) activity. Pyrazoline derivatives were found to be more potent than pyrazoles. Docking studies of the most potent LOX inhibitor 2g highlight hydrophobic interactions with VAL126, PHE143, VAL520 and LYS526 and a halogen bond between the chlorine atom and ARG182.
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46

Kos, Danisovic, Novakova, Zamborsky, Devinsky, and Jampilek. "Antibacterial N-Arylcinnamamides as Anti-inflammatory Agents." Proceedings 22, no. 1 (August 8, 2019): 48. http://dx.doi.org/10.3390/proceedings2019022048.

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47

Flier, M., S. P. M. Geelen, and J. L. L. Kimpen. "Anti-Inflammatory Adjuvant Agents in Bacterial Meningitis." Current Medicinal Chemistry -Anti- Inflammatory & Anti-Allergy Agents 1, no. 1 (April 1, 2002): 55–62. http://dx.doi.org/10.2174/1568014024606575.

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48

Korkina, L., V. Kostyuk, C. De Luca, and S. Pastore. "Plant Phenylpropanoids as Emerging Anti-Inflammatory Agents." Mini-Reviews in Medicinal Chemistry 11, no. 10 (September 1, 2011): 823–35. http://dx.doi.org/10.2174/138955711796575489.

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49

Shrier, Ian, and Steven Stovitiz. "Do Anti-Inflammatory Agents Promote Muscle Healing?" Physician and Sportsmedicine 33, no. 6 (June 2005): 12. http://dx.doi.org/10.3810/psm.2005.06.100.

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50

Rudge, S. "The Clinical Pharmacology of Anti-Inflammatory Agents." Annals of the Rheumatic Diseases 46, no. 7 (July 1, 1987): 567. http://dx.doi.org/10.1136/ard.46.7.567-b.

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