Relevant bibliographies by topics / Anti-inflammatory agents

Academic literature on the topic 'Anti-inflammatory agents'

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Published: 4 June 2021
Last updated: 29 July 2024

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Journal articles on the topic "Anti-inflammatory agents"

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Davis, L. "Ocean Anti-Inflammatory Agents." Science News 130, no. 11 (September 13, 1986): 164. http://dx.doi.org/10.2307/3971034.

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Mohamed, Mosaad S., Aymn E. Rashad, Mostafa Adbel-Monem, and Samar S. Fatahalla. "New Anti-Inflammatory Agents." Zeitschrift für Naturforschung C 62, no. 1-2 (February 1, 2007): 27–31. http://dx.doi.org/10.1515/znc-2007-1-205.

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The pyrrole derivatives 1a, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to the standard drug indomethacin.
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KAWAI, SHIN'ICHI. "Trends of development of anti-inflammatory agents. Antisense therapy as anti-inflammatory agents." Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 28, no. 1 (1997): 73–74. http://dx.doi.org/10.3999/jscpt.28.73.

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Lehra, K. S., S. Goyal, B. S. Bajwa, R. Kaur, and S. Singh. "ANTI-INFLAMMATORY AGENTS FROM PLANTS." INDIAN DRUGS 49, no. 04 (April 28, 2012): 5–11. http://dx.doi.org/10.53879/id.49.04.p0005.

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Most of the available non-steroidal anti-inflammatory drugs are devoid of gastro protective property.Therefore, the search for new anti-inflammatory agents from the huge array of medicinal plant resources is intensifying. Guggul sterones, boswellic acid, curcumin, withaferin-A and and rographolide have been reported to be promising anti-inflammatory agents in animal models. Scientists are of the view that there is acute shortage of leads for developing anti-inflammatory drugs. We need to initiate pending work on these phyto-constituents with emphasis on side effect profile. This paper provides an overview on the recent findings of some plants having anti-inflammatory activity and chemical constituents isolated from them.
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Avti, Pramod K., and Ashok Kakkar. "Dendrimers as anti-inflammatory agents." Brazilian Journal of Pharmaceutical Sciences 49, spe (2013): 57–65. http://dx.doi.org/10.1590/s1984-82502013000700006.

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Dendrimers constitute an intriguing class of macromolecules which find applications in a variety of areas including biology. These hyperbranched macromolecules with tailored backbone and surface groups have been extensively investigated as nanocarriers for gene and drug delivery, by molecular encapsulation or covalent conjugation. Dendrimers have provided an excellent platform to develop multivalent and multifunctional nanoconjugates incorporating a variety of functional groups including drugs which are known to be anti-inflammatory agents. Recently, dendrimers have been shown to possess anti-inflammatory properties themselves. This unexpected and intriguing discovery has provided an additional impetus in designing novel active pharmaceutical agents. In this review, we highlight some of the recent developments in the field of dendrimers as nanoscale anti-inflammatory agents.
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Tsicopoulos, A., and P. de Nadai. "Antihistamines as anti-inflammatory agents." Clinical & Experimental Allergy 33, no. 11 (November 2003): 1476–78. http://dx.doi.org/10.1046/j.1365-2222.2003.01802.x.

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Nuutinen, LS. "Non-steroidal anti-inflammatory agents." Acta Anaesthesiologica Scandinavica 37 (December 1993): 124–25. http://dx.doi.org/10.1111/j.1399-6576.1993.tb03655.x.

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Flanagan, Thomas W., and Charles D. Nichols. "Psychedelics as anti-inflammatory agents." International Review of Psychiatry 30, no. 4 (July 4, 2018): 363–75. http://dx.doi.org/10.1080/09540261.2018.1481827.

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Vader, L. "Non steroidal anti-inflammatory agents." Insight - the Journal of the American Society of Ophthalmic Registered Nurses 25, no. 1 (March 2000): 20–21. http://dx.doi.org/10.1016/s1060-135x(00)90036-8.

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Serafini, Mauro, Ilaria Peluso, and Anna Raguzzini. "Flavonoids as anti-inflammatory agents." Proceedings of the Nutrition Society 69, no. 3 (June 23, 2010): 273–78. http://dx.doi.org/10.1017/s002966511000162x.

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Epidemiological evidence suggests that a high intake of plant foods is associated with lower risk of chronic diseases. However, the mechanism of action and the components involved in this effect have not been identified clearly. In recent years, the scientific community has agreed to focus its attention on a class of secondary metabolites extensively present in a wide range of plant foods: the flavonoids, suggested as having different biological roles. The anti-inflammatory actions of flavonoids in vitro or in cellular models involve the inhibition of the synthesis and activities of different pro-inflammatory mediators such as eicosanoids, cytokines, adhesion molecules and C-reactive protein. Molecular activities of flavonoids include inhibition of transcription factors such as NF-κB and activating protein-1 (AP-1), as well as activation of nuclear factor-erythroid 2-related factor 2 (Nrf2). However, the in vitro evidence might be somehow of limited impact due to the non-physiological concentrations utilized and to the fact that in vivo flavonoids are extensively metabolized to molecules with different chemical structures and activities compared with the ones originally present in the food. Human studies investigating the effect of flavonoids on markers of inflammation are insufficient, and are mainly focused on flavonoid-rich foods but not on pure molecules. Most of the studies lack assessment of flavonoid absorption or fail to associate an effect on inflammation with a change in circulating levels of flavonoids. Human trials with appropriate placebo and pure flavonoid molecules are needed to clarify if flavonoids represent ancillary ingredients or key molecules involved in the anti-inflammatory properties of plant foods.
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Dissertations / Theses on the topic "Anti-inflammatory agents"

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Jeffers, Melanie Diane. "Tannins as Anti-inflammatory Agents." Miami University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=miami1154451707.

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Perkins, Akeysha A. "Polymeric polyphenols as anti-inflammatory agents." Oxford, Ohio : Miami University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1182258706.

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Chan, Sui Yung. "Transdermal delivery of anti-inflammatory agents." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334523.

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Terra, Barbadora Ximena. "GRAPE-SEED PROCYANIDINS AS ANTI-INFLAMMATORY AGENTS." Doctoral thesis, Universitat Rovira i Virgili, 2009. http://hdl.handle.net/10803/8672.

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L'obesitat és un estat inflamatori que porta a l'activació crònica de la resposta immune caracteritzada per la inducció de gens i mediadors proinflamatoris. L'objectiu principal d'aquesta tesi va ser estudiar els efectes antiinflamatoris de les procianidines i les possibles dianes moleculars modulades per aquests flavonoids. Degut al paper central del macròfag en la inducció de inflamació sistèmica, vam analitzar els efectes d'un extracte de procianidines en un model d'inflamació in vitro. Utilitzant models d'obesitat i síndrome metabòlic en rata, vam avaluar els efectes antiinflamatoris de les procianidines in vivo. Els resultats indiquen que les procianidines actuen com antiinflamatoris in vitro inhibint la resposta inflamatòria al macròfag i in vivo com agents preventius tant de la inflamació local com sistèmica, modulant els nivells de mediadors inflamatoris. Aquests resultats indiquen que les procianidines podrien ser candidats per la suplementació dietètica i components d'aliments funcionals per la prevenció de malalties amb component inflamatòria.
Once established that obesity is an inflammatory condition leading to chronic activation of the immune system response, the aim of this thesis was to characterize and understand if dietary procyanidins could modulate the low grade inflammatory response related to obesity and the Metabolic Syndrome. Due to the central role of macrophages in obesity induced low-grade inflammation, we analyzed procyanidin effects in an in vitro model of inflammation. By using rat models of obesity, we also assessed procyanidin anti-inflammatory effects in vivo. To sum up, our results showed that procyanidins act as anti-inflammatory agents both in vitro, by modulating the macrophage inflammatory response, and in vivo, by preventing both local and systemic inflammation through the modulation the inflammatory mediators. In conclusion, the use of procyandins will represent an additional nutritional approach that, in association with lifestyle interventions, would improve the obesity induced inflammation and as a consequence ameliorate the metabolic syndrome.
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Johns, Gianmarc Grazioli. "Structural requirements for time-dependent and time-independent inhibition of prostaglandin synthase I (COX-1) /." Click here for download, 2007. http://proquest.umi.com/pqdweb?did=1303296611&sid=1&Fmt=2&clientId=3260&RQT=309&VName=PQD.

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Elias, Amer N. "Formulation of topical non-steroidal anti-inflammatory agents." Thesis, Aston University, 1987. http://publications.aston.ac.uk/12538/.

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Reversed-pahse high-performance liquid chromatographic (HPLC) methods were developed for the assay of indomethacin, its decomposition products, ibuprofen and its (tetrahydro-2-furanyl)methyl-, (tetrahydro-2-(2H)pyranyl)methyl- and cyclohexylmethyl esters. The development and application of these HPLC systems were studied. A number of physico-chemical parameters that affect percutaneous absorption were investigated. The pKa values of indomethacin and ibuprofen were determined using the solubility method. Potentiometric titration and the Taft equation were also used for ibuprofen. The incorporation of ethanol or propylene glycol in the solvent resulted in an improvement in the aqueous solubility of these compounds. The partition coefficients were evaluated in order to establish the affinity of these drugs towards the stratum corneum. The stability of indomethacin and of ibuprofen esters were investigated and the effect of temperature and pH on the decomposition rates were studied. The effect of cetyltrimethylammonium bromide on the alkaline degradation of indomethacin was also followed. In the presence of alcohol, indomethacin alcoholysis was observed and the kinetics of decomposition were subjected to non-linear regression analysis and the rate constants for the various pathways were quantified. The non-isothermal, sufactant non-isoconcentration and non-isopH degradation of indomethacin were investigated. The analysis of the data was undertaken using NONISO, a BASIC computer program. The degradation profiles obtained from both non-iso and iso-kinetic studies show that there is close concordance in the results. The metabolic biotransformation of ibuprofen esters was followed using esterases from hog liver and rat skin homogenates. The results showed that the esters were very labile under these conditions. The presence of propylene glycol affected the rates of enzymic hydrolysis of the ester. The hydrolysis is modelled using an equation involving the dielectric constant of the medium. The percutaneous absorption of indomethacin and of ibuprofen and its esters was followed from solutions using an in vitro excised human skin model. The absorption profiles followed first order kinetics. The diffusion process was related to their solubility and to the human skin/solvent partition coefficient. The percutaneous absorption of two ibuprofen esters from suspensions in 20% propylene glycol-water were also followed through rat skin with only ibuprofen being detected in the receiver phase. The sensitivity of ibuprofen esters to enzymic hydrolysis compared to the chemical hydrolysis may prove valuable in the formulation of topical delivery systems.
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Qi, Ji. "Cane Toad Skin Extracts as Anti-Inflammatory and Anti-Cancer Agents." Thesis, Griffith University, 2016. http://hdl.handle.net/10072/365729.

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The skin of the toads is known to be rich in bufadienolide compounds (a group of cardiac glycosides) that exhibit antitumor activity. For example, Huachansu (Cinobufacini), the aqueous extracts from the dried toad skin of Bufo bufo gargarizans Cantor or Bufo melanostictus Schneider, has been widely used in clinical therapy for various cancers in China. Clinical data have indicated that Cinobufacini may have significant anticancer activity with low toxicity and few side effects. Data to date suggest that treatment with Cinobufacini may also enhance the quality of life for patients with cancer. Huachansu contains several groups of compounds including peptides, bufadienolides/cardiac glycosides, cholesterols, indole alkaloids, bufogargarizanines, organic acid, and others. Bufadienolides, such as bufalin, cinobufagin, resibufogenin, and telocinobufagin, are responsible for the anti-cancer properties of Huachansu through disruption of the cell cycle and consequent inhibition of cell proliferation, induction of apoptosis, suppression of the NF-B pathway, immunomodulation and reversal of multi-drug resistance. The Australian cane toad (Bufo marinus) is also known as a source of bufadienolides, therefore is also considered as a new source of candidate lead compounds for drug development. Previous studies have shown that cane toad skin aqueous extracts (CTSAE) exhibited a stronger cardiac glycosides-like activity than the extracts of other organic solvents and have a suppression effect on Na+, K+‐ATPase in experimental models. However, no assay was performed to clarify the chemical constituents and pharmaceutical effects of CTSAE on cancer cells in previous studies.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Medical Science
Griffith Health
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Simi, Anastasia. "Molecular basis for the anti-inflammatory properties of chlomethiazole /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-621-9/.

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Smith, Dustin Ryan. "Studies of natural and synthetic anti-inflammatory compounds." Oklahoma City : [s.n.], 2004.

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Checon, Juliana Tibério [UNESP]. "Atividade anti-inflamatória do extrato liofilizado de Physalis angulata L. em cultura de queratinócitos humanos e seu potencial como ativo dermocosméstico." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/91648.

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Made available in DSpace on 2014-06-11T19:25:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-05-27Bitstream added on 2014-06-13T20:53:17Z : No. of bitstreams: 1 checon_jt_me_botib.pdf: 672285 bytes, checksum: d13a0ee5c101a54f8aed60e3139a2121 (MD5)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
A pele é uma importante barreira biológica que interage com inúmeros estímulos ambientais. O desequilíbrio entre essas interações pode resultar em alterações metabólicas importantes, como processos inflamatórios freqüentes e agressivos ao tecido cutâneo. Assim, produtos com atividade anti-inflamatória tópica são de grande interesse farmacêutico e cosmético. Physalis angulata L. (camapú) da família Solanaceae ocorre principalmente nas regiões Norte e Nordeste do Brasil, onde é usado na medicina popular como anti-inflamatório e no tratamento de problemas da pele. Com base nestas informações, a espécie foi escolhida para esse estudo, onde avaliamos a atividade anti-inflamatória do extrato de camapú em culturas de queratinócitos humanos. Culturas de queratinócitos foram sensibilizadas com LPS (200 μg/ml) e depois tratadas com o extrato hidrometanólico (70%) liofilizado de camapú nas concentrações 15,23; 7,62; 3,81 μL/mL. Avaliamos a atividade anti-inflamatória no sobrenadante das culturas pela quantificação dos mediadores: Interleucinas 1 alfa (IL-1α), 6 (IL-6) e 10 (IL-10), prostaglandina E2 (PGE2) e histamina através de ensaios imunoenzimáticos (ELISA). Os dados foram submetidos à análise estatística (ANOVA e Dunnett). As duas menores concentrações do extrato foram capazes de reduzir a síntese de histamina em até 70% e, em média, 50% da síntese de PGE2, em comparação aos controles incubados apenas com LPS.A maior concentração avaliada do extrato reduziu em 60% a produção de IL-6 e houve diminuição de 30% para as outras duas concentrações quando comparadas ao controle inflamado, enquanto que as duas maiores concentrações do extrato reduziram em 45% a síntese de IL-1 α. Para o perfil da citocina anti-inflamatória IL-10 apenas a menor concentração do extrato foi capaz de aumentar em 40% a concentração dessa interleucina no...
The skin, as the primary interface between the body and the environment can respond to a great range of environmental stimuli. Altered responses can lead to important alterations in the tissue physiology such as an excessive inflammation condition, which can produce effects ranging from mild discomfort to permanent impairment of tissue integrity. The pharmaceutical and cosmetic use of natural products is increasing; therefore, products with potential anti inflammatory activity are very significant for the research in this area. Physalis angulata L. belongs to the Solanaceae family and grows in the North and Northeast regions of Brazil where it is known as Camapu. It is used in popular medicine as anti inflammatory and for skin disorders. Based on this information the extract of this species was assayed in the search for anti inflammatory activity on human keratinocytes cultures. Theses cultures were incubated with LPS (200μg/ml) and then treated with hydromethanolic (70%) extract of lyophilized P. angulata at three concentrations (1.523x10-2, 7.62x10-3, e 3.81x10-3 mg/ml). We evaluated the anti inflammatory activity in cultures supernatants through quantification of inflammatory mediators: Interleukine-6 (IL-6) and 10 (IL-10), prostaglandin E2 (PGE2), Tumor necrosis factor-alpha (TNF-α) and histamine.Statistical analysis was performed (ANOVA e Dunnett) and significant difference was taken as p < 0.05. At the lower concentrations the extract was able to reduce 70% the concentration of histamine and 50% of prostaglandin E2. IL-6 concentrations were reduced by the three concentrations of the extract compared to LPS controls, while the two higher concentrations of the extract reduced by 45% the synthesis of IL-1α.For the profile of anti-inflammatory cytokine IL-10 the lowest concentration of the extract was able to increase 40% its concentration in the culture supernatant.These result ... (Complete abstract click electronic access below)
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Books on the topic "Anti-inflammatory agents"

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Williamson, W. R. Nigel, 1925-, ed. Anti-inflammatory compounds. New York: Dekker, 1987.

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1962-, Sampson Anthony P., and Church Martin 1942-, eds. Anti-inflammatory drugs in asthma. Basel: Birkhäuser, 1999.

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1925-, Allison Anthony C., and Lafferty Kevin J, eds. Immunosuppressive and antiinflammatory drugs. New York, N.Y: New York Academy of Sciences, 1993.

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P, Schleimer Robert, Claman Henry N. 1930-, and Oronsky Arnold L, eds. Anti-inflammatory steroid action: Basic and clinical aspects. San Diego: Academic Press, 1989.

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1941-, Rainsford K. D., Velo G. P, Università di Verona. Institute of Pharmacology., International Meeting on the Side-effects of Anti-inflammatory Analgesic Drugs (3rd : 1991 : Verona, Italy), and European Workshop on Inflammation (13th : 1991 : Verona, Italy), eds. Side-effects of anti-inflammatory drugs 3. Dordrecht: Kluwer Academic Publishers, 1992.

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L, Bonta Ivan, Bray Michael A, and Parnham Michael J. 1951-, eds. The Pharmacologyof inflammation. Amsterdam: Elsevier, 1985.

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L, Bonta I., Bray Michael A, and Parnham Michael J. 1951-, eds. The Pharmacology of inflamation. Amsterdam: Elsevier, 1985.

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P, Famaey J., and Paulus H. E, eds. Therapeutic applications of NSAIDs: Subpopulations and new formulations. New York: M. Dekker, 1992.

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F, Kean Walter, and Buchanan W. Watson, eds. The clinical pharmacology of anti-inflammatory agents. London: Taylor & Francis, 1986.

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Rubin, Bruce K., and Jun Tamaoki, eds. Antibiotics as Anti-Inflammatory and Immunomodulatory Agents. Basel: Birkhäuser-Verlag, 2005. http://dx.doi.org/10.1007/b137084.

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Book chapters on the topic "Anti-inflammatory agents"

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Rhee, Douglas J., Kathryn A. Colby, Lucia Sobrin, and Christopher J. Rapuano. "Anti-Inflammatory Agents." In Ophthalmologic Drug Guide, 69–76. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7621-5_7.

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Knych, Edward T. "Anti-inflammatory Agents." In Drugs, Athletes, and Physical Performance, 105–17. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5499-4_8.

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Hilliard, T. N., and I. M. Balfour-Lynn. "Anti-Inflammatory Agents." In Cystic Fibrosis in the 21st Century, 187–94. Basel: KARGER, 2005. http://dx.doi.org/10.1159/000088576.

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Kruis, Wolfgang, and Mauro Bafutto. "Anti-inflammatory Agents." In Colonic Diverticular Disease, 235–44. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-93761-4_19.

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Patalano, Francesco. "Anti-IgE Agents." In Anti-Inflammatory Drugs in Asthma, 215–27. Basel: Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8751-9_8.

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Hošek, Jan, and Karel Šmejkal. "Flavonoids as Anti-inflammatory Agents." In Compendium of Inflammatory Diseases, 482–97. Basel: Springer Basel, 2016. http://dx.doi.org/10.1007/978-3-7643-8550-7_19.

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Hošek, Jan, and Karel Šmejkal. "Flavonoids as Anti-inflammatory Agents." In Encyclopedia of Inflammatory Diseases, 1–17. Basel: Springer Basel, 2015. http://dx.doi.org/10.1007/978-3-0348-0620-6_19-1.

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Nicklin, S., and K. Miller. "Toxicology of immunoregulatory agents." In Side-Effects of Anti-Inflammatory Drugs, 245–52. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-010-9775-8_26.

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Stoner, Gary, and Li-Shu Wang. "Natural Products as Anti-inflammatory Agents." In Obesity, Inflammation and Cancer, 341–61. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-6819-6_13.

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Newburg, David S. "Overview: Immunomodulatory and Anti-Inflammatory Agents." In Advances in Experimental Medicine and Biology, 195–96. Boston, MA: Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1371-1_25.

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Conference papers on the topic "Anti-inflammatory agents"

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YE, Byeongjin, Hyug Moo Kwon, Soo Youn Choi, Jun Ho Lee, Hyun Je Kang, and Cheol-Min Park. "Abstract 1290: Development of anti inflammatory agents targeting TonEBP for treatment of chronic inflammatory diseases." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1290.

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YE, Byeongjin, Hyug Moo Kwon, Soo Youn Choi, Jun Ho Lee, Hyun Je Kang, and Cheol-Min Park. "Abstract 1290: Development of anti inflammatory agents targeting TonEBP for treatment of chronic inflammatory diseases." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-1290.

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Chukwuma, Ifeoma Felicia, Victor Onukwube Apeh, Florence Nkechi Nworah, Chidi Augustine Madueke, and Valentine Odirachukwumma Nwanelo. "The Impacts of Anti-Inflammatory Agents on COVID-19 Cytokine Storm." In ECMS 2021. Basel Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/ecms2021-10910.

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Mahendran, Rhamiya, Paul Bassin, Mike Cook, Sharon Rossiter, Abigail Martin, and Victoria Hutter. "Late Breaking Abstract - Anti-inflammatory activity of novel transtilbene sulfonamide analogues as potential novel therapeutic agents for inflammatory lung disease." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa2471.

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Josan, JS, K. Pokludova, S. Devi, S. Srinivasan, JA Katzenellenbogen, and KW Nettles. "Abstract P2-08-07: Anti-proliferative and anti-inflammatory estrogen receptor agents for treatment of endocrine-resistant breast cancer." In Abstracts: 2016 San Antonio Breast Cancer Symposium; December 6-10, 2016; San Antonio, Texas. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.sabcs16-p2-08-07.

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Shand, FH, SY Langenbach, SP Ma, BJ Wheaton, B. Leung, T. Harris, MJ Schuliga, J. Ziogas, and AG Stewart. "The Endogenous Estrogen Metabolite 2-Methoxyestradiol: Prototype for a New Class of Anti-Inflammatory Agents." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5667.

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Donina, Zhanna. "Nonsteroid anti-inflammatory agents depress inflammation-related respiratory disoders and hypoxia-induced mortality. Experimental model." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.2758.

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Myazina, Anna, Bibik E. Yurievna, Dimitry S. Krivokolysko, and Pankov A. Alexandrovich. "New 4-(2-furyl)-1,4-dihydropyridine-2-thiols as potential agents with anti-inflammatory activity." In 7th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/ecmc2021-11370.

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Lee, YG, JE Gwag, HG Kim, YH Lee, DS Lee, and NI Baek. "Oleoside type secoiridoids from the flowers of Syringa dilatata and their potential as anti-inflammatory agents." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399917.

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Goodfriend, Amy C., Tré R. Welch, Jian Wang, Kytai T. Nguyen, Romaine F. Johnson, Chet C. Xu, Surendranath R. Veeram Reddy, Alan Nugent, James Richardson, and Joseph M. Forbess. "Design of a MRI-Visible and Radiopaque Drug Delivery Coating for Bioresorbable Stents." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-52146.

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Cardiovascular stents are currently being used for intraluminal stenting of the trachea for tracheomalacia treatment. These devices composed of permanent materials are controversial due to their limitations at internal reinforcement and biocompatibility, especially in pediatrics. We show in a pediatric tracheomalacia rabbit model, a poly-L-lactic acid (PLLA) Double Opposed Helical bioresorbable stent (DH) elicits a more mild inflammatory response in the malacic airway compared to a control metal stent. To further improve efficacy, a multi-drug delivery, bioresorbable coating was designed. The coating design controllably delivers ciprofloxacin (antibiotic) for one week and dexamethasone (anti-inflammatory agent) for three months. The bioresorbable polymeric components also demonstrate feasible visibility utilizing Magnetic Resonance Imaging (MRI). The local multi-drug delivery and imaging capabilities in this coating design in combination with the bioresorbable DH stent will result in a successful intervention specifically design for pediatric tracheomalacia. This design will eliminate long-term risks associated with current permanent devices and provide necessary theranostic agents to facilitate healing and monitor progress via non-invasive imaging techniques.
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Reports on the topic "Anti-inflammatory agents"

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Coleman, C. N. Enhancing Effect of Radiation Therapy Using Non-Steroidal Anti-Inflammatory Agents. Fort Belvoir, VA: Defense Technical Information Center, April 2001. http://dx.doi.org/10.21236/ada398351.

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Coleman, C. N. Enhancing Effect of Radiation Therapy Using Non-Steroidal Anti-Inflammatory Agents. Fort Belvoir, VA: Defense Technical Information Center, October 1999. http://dx.doi.org/10.21236/ada384823.

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Coleman, C. N., and S. T. Palayoor. Enhancing the Effect of Radiation Therapy Using Non-Steroidal Anti-Inflammatory Agents. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada411696.

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Takeda, Mamoru. Neurophysiological Mechanisms Underlying the Attenuation of Nociceptive and Pathological Pain by Phytochemicals: Clinical Application as Therapeutic Agents. Progress in Neurobiology, April 2024. http://dx.doi.org/10.60124/j.pneuro.2024.10.02.

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Although phytochemicals are plant-derived toxins that are primarily produced by plants as a form of defense against insects or microbes, several lines of studies have demonstrated that phytochemicals (e.g., polyphenols, carotenoids, and amino acids) have several beneficial biological actions for human health, such as anti-oxidative, anti-inflammatory, and cardioprotective effects. Recent studies have demonstrated that phytochemicals can modulate neuronal excitability in the nervous system, including nociceptive sensory transmission, so it is possible that phytochemicals could be complementary alternative medicine candidates; specifically, therapeutic agents against pain. The focus of this review is to elucidate the mechanisms underlying the modulatory effects of phytochemicals on neuronal electrical signals, such as generator potentials, action potentials, and postsynaptic potentials, in the nociceptive pathway neurons resulting in potential local anesthetic effects, intravenous anesthesia and analgesic effects, and inflammatory pain relief effects. In addition, we discuss the contribution of phytochemicals to the relief of nociceptive and/or pathological pain and their potential clinical application on the basis of our recent studies in vivo.
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