Relevant bibliographies by topics / Anthraquinones

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Academic literature on the topic 'Anthraquinones'

Author: Grafiati
Published: 4 June 2021
Last updated: 31 July 2024

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Journal articles on the topic "Anthraquinones"

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Drummond, Christopher A., Maria Teresa Molina, Sandra Taliansky, Carl R. Breidenbach, and Carmen F. Fioravanti. "Effects of Quinizarin and Five Synthesized Derivatives on Fifth Larval Instar Midgut Ecdysone 20-Monooxygenase Activity of the Tobacco HornwormManduca sexta." International Journal of Zoology 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/261512.

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The plant allelochemical, quinizarin (1,4-dihydroxy-9,10-anthraquinone), and five anthraquinones that were synthesized from quinizarin, namely, 1,4-anthraquinone; 2-hydroxy-1,4-anthraquinone; 2-methoxy-1,4-anthraquinone; 9-hydroxy-1,4-anthraquinone; and 9-methoxy-1,4-anthraquinone, were assessed as to their effects on the essential, P450-dependent ecdysone 20-monooxygenase system of the insect modelManduca sexta(tobacco hornworm). This steroid hydroxylase converts the arthropod molting hormone, ecdysone, to the physiologically required 20-hydroxyecdysone form.M. sextafifth larval instar midgut homogenates were incubated with increasing concentrations (10−8to 10−3 M) of each of the six anthraquinones followed by ecdysone 20-monooxygenase assessments using a radioenzymological assay. Four of the five anthraquinones exhibitedI50’s of about4×10-6to6×10-2 M. The most effective inhibitors were 2-methoxy-1,4-anthraquinone and 1,4-anthraquinone followed by 9-hydroxy-1,4 anthraquinone and 9-methoxy-1,4-anthraquinone. At lower concentrations the latter anthraquinone stimulated E20M activity. Quinizarin was less inhibitory and 2-hydroxy-1,4-anthraquinone was essentially without effect. Significantly, these studies make evident for the first time that anthraquinones can affect insect E20M activity, and thus insect endocrine regulation and development, and that a relationship between anthraquinone structure and effectiveness is apparent. These studies represent the first demonstrations of anthraquinones affecting any steroid hydroxylase system.
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Hafez Ghoran, Salar, Fatemeh Taktaz, Seyed Abdulmajid Ayatollahi, and Anake Kijjoa. "Anthraquinones and Their Analogues from Marine-Derived Fungi: Chemistry and Biological Activities." Marine Drugs 20, no. 8 (July 25, 2022): 474. http://dx.doi.org/10.3390/md20080474.

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Anthraquinones are an interesting chemical class of polyketides since they not only exhibit a myriad of biological activities but also contribute to managing ecological roles. In this review article, we provide a current knowledge on the anthraquinoids reported from marine-derived fungi, isolated from various resources in both shallow waters such as mangrove plants and sediments of the mangrove habitat, coral reef, algae, sponges, and deep sea. This review also tentatively categorizes anthraquinone metabolites from the simplest to the most complicated scaffolds such as conjugated xanthone–anthraquinone derivatives and bianthraquinones, which have been isolated from marine-derived fungi, especially from the genera Apergillus, Penicillium, Eurotium, Altenaria, Fusarium, Stemphylium, Trichoderma, Acremonium, and other fungal strains. The present review, covering a range from 2000 to 2021, was elaborated through a comprehensive literature search using the following databases: ACS publications, Elsevier, Taylor and Francis, Wiley Online Library, MDPI, Springer, and Thieme. Thereupon, we have summarized and categorized 296 anthraquinones and their derivatives, some of which showed a variety of biological properties such as enzyme inhibition, antibacterial, antifungal, antiviral, antitubercular (against Mycobacterium tuberculosis), cytotoxic, anti-inflammatory, antifouling, and antioxidant activities. In addition, proposed biogenetic pathways of some anthraquinone derivatives are also discussed.
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Sadiq, Uzma, Fatima Shahid, Harsharn Gill, and Jayani Chandrapala. "The Release Behavior of Anthraquinones Encapsulated into Casein Micelles during In Vitro Digestion." Foods 12, no. 15 (July 27, 2023): 2844. http://dx.doi.org/10.3390/foods12152844.

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The degradation of anthraquinones extracted from aloe vera plants can be prevented by encapsulating them in casein micelles (CMs). The oral, gastric, and intestinal digestion behavior of spray-dried microcapsules of casein micelles loaded with aloe vera-extracted anthraquinone powder (CMAQP), freeze-dried powder (CMFDP), and whole-leaf aloe vera gel (CMWLAG) obtained through ultrasonication was investigated. The results found that CMAQP and CMFDP dissolved slowly and coagulated into large curds during gastric digestion, improving the retention of anthraquinones in the digestive tract. In contrast, CMWLAG structure was destroyed and increased amounts of anthraquinones were released during oral and gastric digestion phases, indicating increased amounts of surface anthraquinones instead of the encapsulation of anthraquinones in the interior of CMs. The strong hydrophobic interactions protected anthraquinones within the core of CM for CMAQP and delayed diffusion. However, during SIF digestion, both CMAQP and CMFDP released significant amounts of anthraquinones, although CMAQP showed a much more controlled release for both aloin and aloe-emodin over SIF digestion time. The release behavior of anthraquinones from CM microcapsules was a function of the type of anthraquinone that was used to encapsulate. The present study provides insight into the release behavior of loaded bioactive compounds using food-grade CMs as the wall material during in vitro digestion and highlights the importance of the type of bioactive component form that will be encapsulated.
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Kunze, Arno, Ludger Witte, Manuel Aregullin, Eloy Rodriguez, and Peter Proksch. "Anthraquinones in the Leaf Beetle Trirhabda geminata (Chrysomelidae)." Zeitschrift für Naturforschung C 51, no. 3-4 (April 1, 1996): 249–52. http://dx.doi.org/10.1515/znc-1996-3-417.

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Abstract Hydroxylated anthraquinones have been found to accumulate in different developmental stages of the chrysomelid beetle Trirhabda geminata. Eggs, larvae and adults were analyzed by HPLC and GC-MS. Each developmental stage analyzed contained 1,8-dihydroxy-3-methyl-anthraquinone (chrysophanol) and 1,8-dihydroxyanthraquinone (chrysazin). No anthraquinones were detected in the faeces of T. geminata. The level of stored anthraqui­ nones did not change during starvation. In the host plant of this specialist herbivore, the brittlebush Encelia farinosa (Asteraceae), anthraquinones were not detected. Possible biolog­ical functions of anthraquinones stored in T. geminata are discussed.
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Li, Rong-Rong, Xue-Fang Liu, Su-Xiang Feng, Sheng-Nan Shu, Pei-Yang Wang, Na Zhang, Jian-Sheng Li, and Ling-Bo Qu. "Pharmacodynamics of Five Anthraquinones (Aloe-emodin, Emodin, Rhein, Chysophanol, and Physcion) and Reciprocal Pharmacokinetic Interaction in Rats with Cerebral Ischemia." Molecules 24, no. 10 (May 17, 2019): 1898. http://dx.doi.org/10.3390/molecules24101898.

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(1) Background: Rhubarb anthraquinones—a class of components with neuroprotective function—can be used to alleviate cerebral ischemia reperfusion injury. (2) Methods: The three pharmacodynamic indicators are neurological function score, brain water content, and cerebral infarction area; UPLC-MS/MS was used in pharmacokinetic studies to detect plasma concentrations at different time points, and DAS software was used to calculate pharmacokinetic parameters in a noncompartmental model. (3) Results: The results showed that the pharmacodynamics and pharmacokinetics of one of the five anthraquinone aglycones could be modified by the other four anthraquinones, and the degree of interaction between different anthraquinones was different. The chrysophanol group showed the greatest reduction in pharmacodynamic indicators comparing with other four groups where the rats were administered one of the five anthraquinones, and there was no significant difference between the nimodipine group. While the Aloe-emodin + Physcion group showed the most obvious anti-ischemic effect among the groups where the subjects were administered two of the five anthraquinones simultaneously. Emodin, rhein, chrysophanol, and physcion all increase plasma exposure levels of aloe-emodin, while aloe-emodin lower their plasma exposure levels. (4) Conclusions: This experiment provides a certain preclinical basis for the study of anthraquinone aglycones against cerebral ischemia and a theoretical basis for the study of the mechanism of interaction between anthraquinones.
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Gupta, Richa K., Ganesh M. S. Thakuri, Gan B. Bajracharya, and Ram Narayan Jha. "Synthesis of antioxidative anthraquinones as potential anticancer agents." BIBECHANA 18, no. 2 (June 9, 2021): 143–53. http://dx.doi.org/10.3126/bibechana.v18i2.31234.

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Antioxidant and antibacterial activities of natural anthraquinones namely chrysophanol (1) and emodin (2), and synthesized anthraquinones viz. 2-methylanthraquinone (3), anthraquinone (4), 2-bromoanthraquinone (5), rubiadin (6), chrysophanol diacetate (7), rubiadin diacetate (8) and 1,8-dimethoxy-3-methylanthraquinone (9) were investigated. Anthraquinones 9, 3, 6, 5 and 2 exhibited a high DPPH• radical scavenging capacity (IC50 = <500 μg/mL) showing their therapeutic potentiality for the treatment of cancers. These anthraquinones 1-9 have also displayed a weak to moderate antibacterial activity against Bacillus subtilis. Chrysophanol diacetate (7) including emodin (2) have been appeared as the valuable antibacterials. BIBECHANA 18 (2) (2021) 143-153
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Manojlovic, N. T., S. Solujic, S. Sukdolak, and Lj Krstic. "Isolation and antimicrobial activity of anthraquinones from some species of the lichen genus Xanthoria." Journal of the Serbian Chemical Society 65, no. 8 (2000): 555–60. http://dx.doi.org/10.2298/jsc0008555m.

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The isolation of six anthraquinones, erythroglaucin, physcion, xanthorin, emodin, fallacinal and teloschistin, from three species of the lichen genus Xanthoria (X. fallax, X. eleg?ns and A. policarpa) is reported. Physcion is the dominant anthraquinone in all species. The anthraquinones showed broad-spectrum antifungal activity and selective activity against some phytopathogenic bacterial species.
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Ammar Rushdan, Nur Afiqah Nadhiah, Nurunajah Ab Ghani, and Nurulfazlina Edayah Rasol. "Review on Anthraquinones Isolated from Rubiaceae Family." Journal of Science and Mathematics Letters 11, Special (November 9, 2023): 163–74. http://dx.doi.org/10.37134/jsml.vol11.sp.18.2023.

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A current economic trend is to highlight natural resources and many plant species are rich sources of anthraquinones. Anthraquinones are a diverse group of natural compounds extensively studied in various articles. Commonly used for dyes with 30% of it contributed to textile industry. Anthraquinone plays an important chromophore in cancer chemotherapy. They are widely distributed in Rubiaceae family and exhibit various biological activities. Malaysian Rubiaceae, especially plants from Morinda, Rennellia, Psychotria, and Prismatomeris genera, have been known to be rich in anthraquinone content, especially in the roots. The current review aims to provide a comprehensive update on the isolation of anthraquinones from Rubiaceae family in Malaysia. It also discussed the taxonomy, chemistry, and pharmacology studies of the genus. Through the years, 45 anthraquinones have been reported from various species of Rubiaceae demonstrating promising pharmacological activities. The information presented in this review can provide a scientific foundation for future research on the possible therapeutic applications of the species. Enhancing the links between plant biological effects and traditional uses with their chemical characterization.
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Su, Guang-Yao, Ming-Long Chen, and Kui-Wu Wang. "Natural New Bioactive Anthraquinones from Rubiaceae." Mini-Reviews in Organic Chemistry 17, no. 7 (October 9, 2020): 872–83. http://dx.doi.org/10.2174/1570193x17666200107092510.

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Rubiaceae family belongs to the Gentianales, it contains 650 genera and 13,000 species and its worldwide distribution makes it the fourth largest angiosperms. Rubiaceae contains a large amount of anthraquinone compounds, especially in the roots. Anthraquinones are very important natural products with various bioactivities, including antibacterial, antiviral, cytotoxic and antitumor, which make it play an important role in recent research. In the previous study, many researchers have reported anthraquinones from Rubiaceae in different aspects. The present paper provides an overview of the bioactive properties of new naturally occurring anthraquinones and its structural diversity that have been isolated from the Rubiaceae family in recent years. The article covers the literature from 2007 to 2018, overall 95 new anthraquinones.
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Lyčka, Antonín, Libuše Havlíčková, Alois Koloničný, and Josef Jirman. "15N NMR study of amino-imino tautomerism in derivatives of 1,4-bis(substituted amino)-9,10-anthraquinones and 1,4-bis(substituted amino)-2,3-dihydro-9,10-anthraquinones." Collection of Czechoslovak Chemical Communications 52, no. 3 (1987): 736–41. http://dx.doi.org/10.1135/cccc19870736.

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The 15N chemical shifts and 1J(15N, H) coupling constants of 1,4-bis(substituted amino)-9,10-anthraquinones and 1,4-bis(substituted amino)-2,3-dihydro-9,10-anthraquinones indicate that these derivatives exist as true aminoderivatives except for 1,4-bis(phenylamino)-2,3-dihydro-9,10-anthraquinone which forms a tautomeric mixture of the amino and imino forms in deuteriochloroform and hexadeuteriodimethyl sulphoxide.
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Dissertations / Theses on the topic "Anthraquinones"

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Askari, Syed Hasan. "Synthesis and medium-dependent photochemistry of tetrahydro-1,4- Anthraquinones and Anthraquinols : structure-reactivity relationships from X-ray crystallography." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26954.

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Previous work from our laboratory has been concerned with investigating the photochemical reactivity of tetrahydro-1,4-naphthalenedione and tetrahydronaphthoquinol systems, both in the solid state and in solution. The fascinating results obtained prompted us to extend the studies to the analogous tetrahydro-1,4-anthracenediones, tetrahydro-5,12-naphthacenediones and tetrahydroanthraquinol systems. Tetrahydro-1,4-anthracenedione is expected to undergo bis-enolization with extreme ease, and therefore its preparation requires mild and neutral conditions. These compounds were prepared by Diels-Alder reaction between o-quinodimethane and p-benzoquinone and other p-substituted quinones o-Quinodimethane was generated in situ by sulphur dioxide extrusion from 3,6-dihydrobenzo[b]oxathiin-2-oxide. The photochemistry of the tetrahydro-1,4-anthracenediones, tetra-hydro-5,12-naphthalenedione and tetrahydroanthraquinols has been investigated both in the solid state and solution. The effect of the solid state medium on the photoreactivity, compared to the solution, is significant; the nature and/or the number of the photoproducts formed in the solid state is generally different from the results obtained in solution. These differences have been explained on the basis of the crystal and molecular structures of the reactants. Special steric effects, which may impede the photochemical reactions in the solid state have been identified. The values of the geometric parameters (d, r and A) for hydrogen atom abstraction are found to be similar to those observed in earlier studies by Scheffer et al. It has been found that the o-quinodimethane/2,3-dimethyl-l,4-naphthoquinone adduct affords, via β-hydrogen atom abstraction and closure of the resulting 1,3-biradical, a cyclopropanol. The cyclopro-panol itself undergoes photolysis initiated by a novel ring opening process. Irradiation of crystals of the adduct does not result in any cyclopropanol. The reasons for the non-reactivity of the Diels-Alder adduct in the solid state have been suggested to be due to the non-bonded steric interactions between the lattice neighbors as shown by the X-ray crystal structure. The photorearrangement of one substrate, namely 2,3,4a,9a-tetra-methyl-4a,9a,9,10-tetrahydro-1,4-anthracenedione is found to be controlled by the temperature, multiplicity, and phase of the reaction. By carrying out the reaction at or above room temperature or in the presence of a sensitizer or in the crystalline state, the reaction can be forced in one direction. Lowering the photolysis temperature causes the formation of another product. The nature of the photoproduct is independent of the temperature in the crystalline state. The results have been interpreted in terms of a required ring inversion which is needed for the formation of the low temperature photoproduct (see Scheme 44). The ring inversion is not allowed in the solid state.
Science, Faculty of
Chemistry, Department of
Graduate
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2

Samp, James Christian. "A comprehensive mechanism for anthraquinone mass transfer in alkaline pulping." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/24767.

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Thesis (Ph.D.)--Chemical Engineering, Georgia Institute of Technology, 2008.
Committee Chair: Dr. Jeff Empie; Committee Member: Dr. Bill Koros; Committee Member: Dr. Jim Frederick; Committee Member: Dr. Tom McDonough; Committee Member: Dr. Xin-Sheng Chai
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Mitchell, Anthony Stewart, and mikewood@deakin edu au. "Synthetic studies towards anthraquinones." Deakin University. School of Biological and Chemical Sciences, 1994. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20051017.151445.

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The oxidation of substituted phenols with phenyliodonium diacetate in methanol was found to afford 2,4-cyclohexadienones, 2,5-cyclohexadienones or mixtures of isomers depending on the substrate being oxidized. A reaction mechanism was proposed for this oxidation which involved an intermediate aryloxenium ion. A strong correlation was observed between the experimentally determined product ratios and the results predicted by calculation of the LUMO coefficients of the proposed intermediates, Annulation of these cyclohexadienones with the anion derived from cyanophthalide afforded substituted anthraquinones in high yields. The chemistry relating to the annulation of Michael acceptors with phthalide anions was comprehensively reviewed. A mild selective method for the oxidation of hydroquinones to quinones using dibenzoyl peroxide and base is presented. A general synthetic approach to C-glycosylanthraquinones was presented, based on the annulation of a C-glycosylcyclohexadienone with the anion derived from cyanophthalide, A suitable precursor to a C-glycosylcyclohexadienone, 2-(2’,3’,4’,6’-tetra-0-acetyl-|3-D-glucopyranosyl)benzyloxybenzene, was prepared via the reaction of benzoylbromoglucose with 2-benzyloxyphenylmagnesium bromide, A group of molecules were prepared by a Marschalk reaction between /ewcoquinizarin and aldehydo-sugsrs. These compounds are potential bioreductive alkylating agents in which molecular simplicity can be achieved without overly sacrificing DNA binding ability.
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Rabinowitz, Daniel Joshua. "Electrochemical Studies of Substituted Anthraquinones." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/chemistry_theses/15.

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Electrochemical potentials of a series of anthraquinone derivatives were studied in both aqueous solution and acetonitrile. The long term goal of this work was to find derivatives which could be reduced easily for studies of photoinduced electron transfer in DNA. Our immediate goal was to find the substitution group that gave the least negative redox potential value. Of all derivatives studied, the anthraquinone imides as a class had the least negative redox potentials, in the range of -0.600 to -0.550 V vs. SCE. One of the anthraquinones studied, one derivative (deoxyadenosine conjugated with an ethynyl linker to an anthraquinone with two ester substituents) was also in this range. A study of a series of anthraquinones conjugated with ethynyl and ethanyl linkers showed that the ethynyl linker was more effective than the ethanyl linker in lowering the redox potential of anthraquinone.
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Spargo, P. L. "Biomimetic synthesis of polyketide anthraquinones." Thesis, University of Cambridge, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383910.

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Zhang, Hai Long. "Study on anthraquinones from morinda officinalis." Thesis, University of Macau, 2009. http://umaclib3.umac.mo/record=b2158154.

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Moore, John Neville. "Time resolved spectroscopy of water-soluble anthraquinones." Thesis, Imperial College London, 1986. http://hdl.handle.net/10044/1/38109.

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Chigr, Mohamed. "Mise au point d'une synthèse régiosélective d'amino-anthraquinones et d'aza-anthraquinones par la réaction de Diels-Alder : activité antitumorale de quelques dérivés." Lyon 1, 1989. http://www.theses.fr/1989LYO1T034.

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Moroh, Jean-Luc Aboya. "Résistance bactérienne et phytomolécules antimicrobiennes issues de Morinda morindoides." Thesis, Brest, 2013. http://www.theses.fr/2013BRES0028/document.

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Nous assistons durant ces trente dernières années à une croissance de la fréquence d’apparition des bactéries résistantes aux antibiotiques. Face à la récurrence des infections difficiles à traiter dues à ces bactéries pathogènes multi-résistantes, le renforcement de l’arsenal des antimicrobiens fait partir des préoccupations majeures de santé publique. À ce titre, une approche ethno-pharmacologique a été initiée dans le cadre d’une coopération entre le laboratoire de pharmacodynamie biochimique (Université Félix Houphouët-Boigny, Côte d’Ivoire) et le laboratoire universitaire de biodiversité et d’écologie microbienne(Université de Bretagne Occidentale, France). Dans cette approche, les habitudes traditionnelles d’automédication par les plantes médicinales ont été exploitées pour identifier de nouvelles sources de composés antimicrobiens. Dans une première partie de cette présente étude, une investigation sur les résistances bactériennes en Côte d’Ivoire a montré non seulement une évolution de la fréquence d’apparition des bactéries résistantes aux antibiotiques dans le temps, mais aussi une évolution de ces souches résistantes vers des différents types de multi-résistances. Dans la seconde partie, Morinda morindoides, une plante médicinale ivoirienne, a suscité notre attention pour la recherche de substances antimicrobiennes. À partir de 18 extraits des différents organes de cette plante, des tests d’activité antimicrobienne ont permis de justifier son utilisation en médecine traditionnelle. L’extrait à l’acétonitrile de la racine qui affiche l’activité la plus intéressante a servi pour isoler et caractériser 12 phytomolécules antimicrobiennes dont une se distingue par sa structure chimique originale, la morindoïdine. En plus de leurs paramètres antimicrobiens, d’autres propriétés biologiques de ces substances ont été évaluées telles que, leur pouvoir antioxydant, leur cytotoxicité, leur activité hémolytique et leur cible moléculaire. Cette évaluation a révélé un mode d’action sans doute proche de celui des quinolones
We are witnessing over these last thirty years a growing frequency of occurrence of antibiotic-resistant bacteria. This observation is coupled with a reduction in discovery of new antimicrobials. Given the recurrence of difficult to treat infections caused by these pathogens become multidrug resistant, strengthening the antimicrobial arsenal is one of the main public health concerns. To this end, an ethnopharmacological approach has been developed. Within the framework of cooperation between the laboratory of Biochemical pharmacodynamics (University of Cocody, Côte d'Ivoire) and the laboratory of microbial biodiversity and ecology (LUBEM EA 3882, University of Brest, France), traditional self-medication habits affecting more than 70% of the population of Cote d'Ivoire were analyzed to identify new sources of antimicrobial compounds. In the first part of this study, an investigation of bacterial resistance in Côte d'Ivoire has revealed not just an increase in the frequency of occurrence of antibiotic-resistant bacteria in time, but also an evolution of resistant strains toward different types of antibiotics. In the second part, Morinda morindoides, an Ivorian medicinal plant aroused our attention for the research of antimicrobial substances. From 18 extracts from different organs of this plant the antimicrobial activity tests were performed. The acetonitrile extract of the root which exhibit the most interesting activity was used to isolate and characterize 12 antimicrobial phytomolecules. One of these compounds exhibits an original chemical structure named morindoidine. In addition to their antimicrobial activity, other biological properties of these substances have been evaluated such as their antioxidant potency, their cytotoxicity, their hemolytic activity and their molecular target. This assessment revealed a mode of action probably close to that of quinolones
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Martin, Philippe. "Synthèse de quinones polycycliques et d'analogues inhibiteurs potentiels de topoisomérases et de l'interleukine 1." Poitiers, 1997. http://www.theses.fr/1997POIT2298.

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Les quinones sont une famille de composes presentant souvent des activites biologiques remarquables (antibiotique, anticancereuse, antioxydante. . . ). C'est le cas notamment de la doxorubicine et de la daunorubicine qui sont des antitumoraux utilises cliniquement. Les quinones, mono ou polycycliques ont egalement un interet du point de vue chimique (par exemple, la ddq est un bon agent de deshydrogenation). Les benzoquinones, les naphtoquinones, les anthraquinones (comme la diacerheine, compose anti-arthrosique) et les anthracyclines (tetrahydronaphtacenequinones) sont les quinones les plus couramment etudiees. Par contre, les composes de type naphtacenequinones sont peu decrits dans la litterature, bien que certaines aient montre une activite biologique importante : ces composes possedent une capacite d'inhibition vis-a-vis des topoisomerases 1 et 2, enzymes essentielles a la replication de l'adn. Generalement, c'est la topoisomerase de type 2 qui est la cible des antitumoraux utilises cliniquement. Ce mode d'action presente cependant certaines limites : apparition d'une resistance multidrogue acquise et faible efficacite sur certains types de cancers (colon en particulier). Par ailleurs, la camptothecine (alcaloide) est une molecule possedant une bonne specificite vis-a-vis de la topoisomerase 1 qui a conduit recemment a la mise sur le marche de plusieurs analogues. Apres un rappel des proprietes et des mecanismes d'action des topoisomerases, la synthese de naphtacenequinones isolees recemment, en particulier la saintopine et uce 6, ainsi que le precurseur de ce dernier compose, la tetracenomycine d, a ete etudiee. Dans un second temps, la synthese d'analogues d'une anthraquinone, la diacerheine, utilisee pour le traitement de l'arthrose est decrite. Cet anti-inflammatoire, a l'activte tres prometteuse, presente cependant des effets indesirables que les analogues de synthese vises ne devraient pas posseder. Apres un bref rappel des mecanismes impliques dans l'arthrose, la preparation de nouvelles anthraquinones ainsi que des molecules de structure proche (xanthones) est reportee.
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Books on the topic "Anthraquinones"

1

Mäkelä, Reijo. ESR, ENDOR and triple resonance study on substituted 9,10-anthraquinone radicals in solution. Jyväskylä, Finland: Jyväskylän yliopisto, 1990.

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2

Giles, Yvonne. Synthesis, DNA interactions and activation of novel cytotoxic anthraquinones. Leicester: De Montfort University, 1999.

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C, Goyal Gopal, and Technical Association of the Pulp and Paper Industry., eds. Anthraquinone pulping: A Tappi press anthology of published papers, 1977-1996. Atlanta, GA: Tappi press, 1997.

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Ijaz, Taeeba. Anthraquinone-peptide conjugates as inhibitors of DNA transcription factor binding. Leicester: De Montfort University, 1998.

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Rhodes, Christopher Mark. Part 1: the synthesis and study of anthracine and anthraquinone-containing polymers by means of a precursor route: Part 2: a kinetic study of model reactions of an epoxy resin cure. Manchester: University of Manchester, 1996.

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Anthraquinone Pulping. Tappi Pr, 1997.

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Dutta, Tapas. Kraft pulping of Douglas-fir with soluble anthraquinone. 1988.

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Dutta, Tapas. Kraft pulping of Douglas-fir with soluble anthraquinone. 1988.

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Reed, Gregg Arthur. Nucleophilicity of hydroxide, hydrosulfide, and anthrahydroquinone ions toward saturated and unsaturated carbon centers at high temperatures. 1988.

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Anthraquinones in plants: Source, safety and applications in gastrointestinal health. 2nd ed. Nottingham: Nottingham University Press, 2010.

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Book chapters on the topic "Anthraquinones"

1

Thomson, R. H. "Anthraquinones." In Naturally Occurring Quinones IV, 309–483. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-009-1551-0_3.

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Fouillaud, Mireille, Yanis Caro, Mekala Venkatachalam, Isabelle Grondin, and Laurent Dufossé. "Anthraquinones." In Phenolic Compounds in Food, 131–72. Boca Raton : CRC Press, Taylor & Francis Group, 2018.: CRC Press, 2018. http://dx.doi.org/10.1201/9781315120157-9.

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Billen, Günter, Ulrich Karl, Thomas Scholl, Klaus Dieter Stroech, and W. Steglich. "Stereochemical Studies on Pre-Anthraquinones and Dimeric Anthraquinone Pigments." In Natural Products Chemistry III, 305–15. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-74017-6_17.

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Seigler, David S. "Benzoquinones, Naphthoquinones, and Anthraquinones." In Plant Secondary Metabolism, 76–93. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4913-0_6.

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Wijnsma, R., and R. Verpoorte. "Anthraquinones in the Rubiaceae." In Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, 79–149. Vienna: Springer Vienna, 1986. http://dx.doi.org/10.1007/978-3-7091-8846-0_2.

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López, Víctor, and Francisco Les. "Fungal Quinones: Benzo-, Naphtho-, and Anthraquinones." In Natural Secondary Metabolites, 607–26. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-18587-8_18.

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Palumbo, Manlio, and Barbara Gatto. "Aminoacyl-Anthraquinones: DNA-Binding and Sequence Specificity." In The Jerusalem Symposia on Quantum Chemistry and Biochemistry, 207–24. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-011-3728-7_15.

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Karukstis, K. K., M. A. Berliner, C. J. Jewell, and K. T. Kuwata. "Competition of Anthraquinones for the QB Binding Domain." In Current Research in Photosynthesis, 579–82. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0511-5_133.

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Hagendoorn, Marc J. M., Linus H. W. van der Plas, and Gert J. Segers. "Accumulation of anthraquinones in Morinda citrifolia cell suspensions." In Primary and Secondary Metabolism of Plants and Cell Cultures III, 227–34. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0237-7_17.

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Toshima, Kazunobu. "Nonnatural Glycosyl Anthraquinones as DNA Binding and Photocleaving Agents." In Anthracycline Chemistry and Biology I, 285–98. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/128_2007_147.

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Conference papers on the topic "Anthraquinones"

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De Kimpe, Norbert, Tuyen Nguyen Van, Matthias D’Hooghe, and Siegfried Pattyn. "Application of Ring Closing Metathesis Towards Functionalized 1,4-dihydro-9,10-anthraquinones and Anthraquinones Using Grubbs’ Catalyst." In The 8th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01951.

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Milanovic, Žiko, Marko Antonijevic, Ana Kesic, Dusan Dimic, and Jelena Đorovic Jovanovic. "ANTIOKSIDATIVNI KAPACITET ANTRAHINONA IZ BILJKE RUBIA CORDIFOLIA LINN." In XXVI savetovanje o biotehnologiji sa međunarodnim učešćem. University of Kragujevac, Faculty of Agronomy, 2021. http://dx.doi.org/10.46793/sbt26.487m.

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In this study, the antioxidant and antiradical capacities of anthraquinones from Rubia cordifolia Linn were determined using the DFT method. The thermodynamically most favorable reaction pathways of antioxidant mechanisms were defined, as well as the most favorable antiradical reaction mechanisms for the deactivation of methylperoxyl and methoxy radicals. The calculations were done in the gas phase. HAT is thermodynamically the most favorable mechanism of antioxidant action of the studied anthraquinones, while the most probable mechanism of deactivation of methylperoxyl and methoxy radicals is the SPLET mechanism.
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Dimmer, Jesica Ayelen, Camila Ramos Silva, Susana Carolina Nunez Montoya, Jose Luis Cabrera, and Martha S. Ribeiro. "Photodynamic activity of natural anthraquinones on fibroblasts." In Photonic Diagnosis and Treatment of Infections and Inflammatory Diseases, edited by Tianhong Dai. SPIE, 2018. http://dx.doi.org/10.1117/12.2290666.

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Tarasova, M. I. "Prospects for the use of Chrysanthemum coronarium (L.) in medicinal crop production." In Растениеводство и луговодство. Тимирязевская сельскохозяйственная академия, 2020. http://dx.doi.org/10.26897/978-5-9675-1762-4-2020-95.

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А brief overview of the relevance of using garland chrysanthemum (Glebionis coronaria (L.) Cass. ex Spach syn. Chrysanthemum coronarium (L.)) as a raw material in the preparation of medicaments is introduced in this article. High contents of micro- and macroelements were found in garland chrysanthemum, as well as other biologically active compounds, of which anthraquinones, flavonoids, carotenoids and ascorbic acid can be considered the main ones, likewise vitamins B, PP and free amino acids.
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Thiemann, Thies, Yasuko Tanaka, and Jesus Iniesta. "Halogenated Thiophenes as Precursors in the Preparation of Halogenated and Arylated Anthraquinones." In The 12th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2008. http://dx.doi.org/10.3390/ecsoc-12-01221.

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Zhu, Feng, Guangying Chen, Xin Chen, Yihua Yuan, Meizhen Huang, Wenzhou Xiang, and Huili Sun. "Structural Elucidation of Three Anthraquinones from a Marine-Derived Mangrove Endophytic Fungus (Isolate 1850)." In 2008 International Conference on Biomedical Engineering And Informatics (BMEI). IEEE, 2008. http://dx.doi.org/10.1109/bmei.2008.71.

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Demirezer Lutfiye, O., M. Uzun, and Z. Guvenalp. "Determination and comparison of sun protection factors (SPF) of main anthraquinones and their glycosides." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608171.

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Hakim, Budi Lukman, and Handoko Subawi. "Utilization of natural anthraquinones and P-allylphenol as qualified hand sanitizer ingredients to meet health organization standards." In PROCEEDINGS OF THE 9TH INTERNATIONAL SYMPOSIUM ON INNOVATIVE BIOPRODUCTION INDONESIA ON BIOTECHNOLOGY AND BIOENGINEERING 2022: Strengthening Bioeconomy through Applied Biotechnology, Bioengineering, and Biodiversity. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0171711.

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Bai, Ming, Yan Li, Mingsan Miao, Ting Wang, and Yuyin Xu. "Effects of Total Anthraquinones of Polygonum Cuspidatum on the Levels of Insulin, Leptin and C-Peptide in Serum in Diabete Rat Model." In 2015 International Conference on Social Science, Education Management and Sports Education. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/ssemse-15.2015.326.

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Burger, E. D., and J. M. Odom. "Mechanisms of Anthraquinone Inhibition of Sulfate-Reducing Bacteria." In SPE International Symposium on Oilfield Chemistry. Society of Petroleum Engineers, 1999. http://dx.doi.org/10.2118/50764-ms.

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Reports on the topic "Anthraquinones"

1

Su, Ning, Jerald S. Bradshaw, Xian X. Zhang, Paul B. Savage, and Krzystof E. Krakowiak. Syntheses of Diaza-18-Crown-6 Ligands Containing Two Units Each of 4-Hydroxyazobenzene, Benzimidazole, Uracil, Anthraquinone, or Ferrocene Groups. Fort Belvoir, VA: Defense Technical Information Center, April 1999. http://dx.doi.org/10.21236/ada361715.

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Integration of the Mini-Sulfide Sulfite Anthraquinone (MSS-AQ) Pulping Process and Black Liquor Gasification in a Pulp Mill. Office of Scientific and Technical Information (OSTI), January 2010. http://dx.doi.org/10.2172/970980.

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