Journal articles on the topic 'Anoxemia'

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1

Peñaloza Ramella, Dante. "El test cardiológico de anoxemia." Anales de la Facultad de Medicina 34, no. 4 (October 18, 2014): 677. http://dx.doi.org/10.15381/anales.v34i4.9548.

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Es perfectamente conocida la importancia fundamental del diagnóstico de certeza del síndrome de Angina de Pecho. Según White, este dindrome constituye el 11.8% de las cardiopatías, lo que demuestra que no es tan infrecuente, sobre todo en las últimas décadas. Es bien sabido, asimismo, el pronóstico relativamente grave de la estenocardia; en la estadística de White, el término medio de vida, después del primer ataque, solo alcanza a 9.1 años. Finalmente, es conocido que, una parte esencial del tratamiento preventivo de los ataques de angor pectoris, es el cambio radical en el modo de vida, lo cual puede acarrear, en muchos casos, consecuencias muy serias para el paciente, desde el punto de vista económico y social. Esta suerte de tratamiento, que interferiría fundamentalmente en la vida del paciente, así como el pronóstico que, como ya hemos dicho, es de relativa gravedad, sólo pueden hacerse justificadamente sobre la base de un diagnóstico indudable del sindrome de angina de pecho.
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2

Horton, A., and C. Reynolds. "B-11Every Breath You Take: Anoxemia." Archives of Clinical Neuropsychology 31, no. 6 (August 31, 2016): 616.3–616. http://dx.doi.org/10.1093/arclin/acw043.86.

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3

Hurtado, Alberto, César Merino, and Ernesto Delgado Febres. "La influencia de la anoxemia sobre la actividad hematopoyética." Anales de la Facultad de Medicina 29, no. 2 (October 18, 2014): 125. http://dx.doi.org/10.15381/anales.v29i2.9636.

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Se han realizado investigaciones, al nivel del mar y en la altura, en varios grupos de sujetos (hombres), sanos y enfermos, concernientes a la influencia de la anoxia anóxica (anoxemia) temporal, intermitente y crónica, sobre la morfología y otras características de la sangre circulante. La literatura relacionada ha sido brevemente revisada.
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4

Larsen, Kaj. "Effect of Anoxemia on the Human Electrocardiogram." Acta Medica Scandinavica 90, S78 (April 24, 2009): 141–49. http://dx.doi.org/10.1111/j.0954-6820.1936.tb15932.x.

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5

Delgado Febres, Ernesto. "La Bilirrubinemia." Anales de la Facultad de Medicina 32, no. 1 (October 18, 2014): 29. http://dx.doi.org/10.15381/anales.v32i1.9583.

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Se ha estudiado la bilirrubinemia en 201 sujetos aduyltos y aparentemente sanos (159 hombres y 42 mujeres), lo que constituye la serie más numerosa que se ha dado sobre este particular. Asimismo se ha estudiado un grupoi de sujetos que, como única anormalidad aparente presentan cifras elevadas de bilirrubina de tipo indirecto y prueba de excreción para este pigmento (en todos los casos donde se estudió) insuficiente; condición ésta que, con diferentes nombres, ha sido estudiada por varios autores, cuyo conocimiento tiene gran valor. Igualmente se ha estudiado la bilirrubinemia y la función hepática relacionado con la excreción de este pigmento en diferentes condiciones de anoxemia; crónica, aguda (exposición por 4 horas y por 7 días); asimismo y desde ambos puntos de vista se estudió un grupo de sujetos nativos trasladados de Morocoha a Lima, a fin de observar el comportamiento de la bilirrubina de la sangre, y de la función hepática correspondiente, cuando se hace cesar la anoxemia. En condiciones patológicas se ha hecho un estudio comparativo y seriado en algunos casos en 144 enfermas, de los datos que proporciona la técnica de Malloy y Evelyn, son los que se suministra la clásica reacción de Van den Bergh.
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6

Kozlova, Elena, Ekaterina Sherstyukova, Viktoria Sergunova, Andrey Grechko, Artem Kuzovlev, Snezhanna Lyapunova, Vladimir Inozemtsev, Aleksandr Kozlov, and Aleksandr Chernysh. "Atomic Force Microscopy and High-Resolution Spectrophotometry for Study of Anoxemia and Normoxemia in Model Experiment In Vitro." International Journal of Molecular Sciences 24, no. 13 (July 3, 2023): 11043. http://dx.doi.org/10.3390/ijms241311043.

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The oxygen content in the blood may decrease under the influence of various physicochemical factors and different diseases. The state of hypoxemia is especially dangerous for critically ill patients. In this paper, we describe and analyze the changes in the characteristics of red blood cells (RBCs) with decreasing levels of oxygen in the RBC suspension from normoxemia to hypoxemia/anoxemia in an in vitro model experiment. The RBCs were stored in hypoxemia/anoxemia and normoxemia conditions in closed and open tubes correspondingly. For the quantitative study of RBC parameter changes, we used atomic force microscopy, digital spectrophotometry, and nonlinear curve fitting of the optical spectra. In both closed and open tubes, at the end of the storage period by day 29, only 2% of discocytes remained, and mainly irreversible types, such as microspherocytes and ghosts, were observed. RBC hemolysis occurred at a level of 25–30%. Addition of the storage solution, depending on the concentration, changed the influence of hypoxemia on RBCs. The reversibility of the change in hemoglobin derivatives was checked. Based on the experimental data and model approach, we assume that there is an optimal level of hypoxemia at which the imbalance between the oxidative and antioxidant systems, the rate of formation of reactive oxygen species, and, accordingly, the disturbances in RBCs, will be minimal.
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7

Ordóñez, J. Hernando. "Biología en la altura." Anales de la Facultad de Medicina 35, no. 1 (October 18, 2014): 193. http://dx.doi.org/10.15381/anales.v35i1.9350.

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La saturación de oxígeno en la sangre de la altura de Bogotá (2,640 metros; es normal o casi normal. En esta altura se han observado los siguientes datos: el pulso es anormal, la tensión arterial no está modificada, el electrocardiograma no muestra signos de anoxemia. No se han observado modificaciones del metabolismo, ni de la respiración ni del sistema nervioso. De una manera excepcional se han observado algunos síntomas leves del mal de las montañas crónicas. Se ha observado una melanosis generalizada la cual es por carencia de algunos factores en la alimentación y parece que la altura tenga un papel secundario en su patogenia. Hace falta estudiar más el comportamiento especial de algunas enfermedades, cardiopatías y neumopatías especialmente, en la altura. Otro tanto puede decirse de las condiciones del ejercicio en la altura.
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8

Voronina, T. A. "Antioxidants/antihypoxants: the missing puzzle piece in effective pathogenetic therapy for COVID-19." Infekcionnye bolezni 18, no. 2 (2020): 97–102. http://dx.doi.org/10.20953/1729-9225-2020-2-97-102.

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This review focuses on the specific characteristics of COVID-19 disease, which leads not only to respiratory impairments (bronchoalveolar epithelium does not retain oxygen, etc.), but also decreases the level of hemoglobin and its ability to transfer oxygen to the organs and tissues and increases the level of heme, resulting in anoxemia, hypoxia in all organs and tissues, and oxidative stress. Mexidol, a drug developed in Russia, is widely used in clinical practice, including the treatment of diseases accompanied by ischemia and hypoxia. Mexidol has antihypoxic and antioxidant effects, can treat mitochondrial respiratory dysfunction, thereby affecting the key processes in different cells of organs and tissues that develop due to hypoxia. Mexidol can be useful in the comprehensive therapy of patients with COVID-19. Key words: COVID-19, antioxidant, antihypoxant, hemoglobin, hypoxia, Mexidol, mitochondrial dysfunction, oxidative stress
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9

Monge M., Carlos. "La estimulación suprarrenal por la anoxemia aguda expresada en la variación de los eosinófilos circulantes." Anales de la Facultad de Medicina 37, no. 1 (October 18, 2014): 100. http://dx.doi.org/10.15381/anales.v37i1.9428.

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Los problemas de la vida en la altitud han suscitado interés y preocupación, e inducido a múltiples estudios a investigadores peruanos y extranjeros. El anhelo de comprensión ha sido tanto del hombre que viviendo allá tiene en equilibrio su fisiología frente al rigor ambiental, como del que habitando a nivel del mar asciende a las altas montañas, siendo sometido así a una "agresión anóxica", contra la que tiene que luchar.
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10

Richalet, Jean-Paul. "The invention of hypoxia." Journal of Applied Physiology 130, no. 5 (May 1, 2021): 1573–82. http://dx.doi.org/10.1152/japplphysiol.00936.2020.

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The word “hypoxia” has recently come to the attention of the general public on two occasions, the Nobel Prize in Medicine or Physiology in 2019 and the recent COVID-19 pandemic. In the academic environment, hypoxia is a current topic of research in biology, physiology, and medicine: in October 2020, there were more than 150,000 occurrences of “hypoxia” in the PubMed database. However, the first occurrence is dated to 1945, while the interest for the effects of oxygen lack on the living organisms started in the mid-19th century, when scientists explored high altitude regions and mainly used the terms “anoxia” or “anoxemia.” I therefore researched online through multiple databases to look for the first appearance of “hypoxia” and related terms “hypoxemia” and “hypoxybiosis” in scientific literature published in English, German, French, Italian, and Spanish. Viault and Jolyet used “Hypohématose” in 1894, but this term has not been used since. Hypoxybiosis first appeared in 1909 in Germany, then hypoxemia in 1923 in Austria, and hypoxia in 1938 in Holland. It was then exported to the United States where it appeared in 1940 in cardiology and anesthesiology. The clinical distinction between anoxia and hypoxia was clearly defined by Carl Wiggers in 1941. Hypoxia (decrease in oxygen), by essence variable in time and in localization in the body, in contrast with anoxia (absence of oxygen), illustrates the concept of homeodynamics that defines a living organism as a complex system in permanent instability, exposed to environmental and internal perturbations.
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11

Kotsiumbas, H. I., and N. P. Vretsona. "Morphofunctional changes in the heart and lung tissues of dogs for isoniazid poisoning." Ukrainian Journal of Veterinary and Agricultural Sciences 2, no. 2 (December 3, 2019): 12–17. http://dx.doi.org/10.32718/ujvas2-2.03.

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The article presents the results of macroscopic, histological and histochemical studies of the heart and lungs of dogs for isoniazid poisoning. A pathoanatomical section of 19 carcasses of dogs of different ages and breeds was performed; heart and lung fragments were selected for morphological examination. Heart and lung samples were fixed in 10 % aqueous formalin neutral solution, Carnua and Buen fluids. Dehydration was carried out in ethanol of increasing concentration and embedded in paraffin. The sections were made on a MC-2 microtome 7 μm thick, stained with hematoxylin and eosin, using the McManus and Brasche technique. Made histopreparations were examined under a Leica DM 2500 light microscope (Switzerland), photo-fixation was performed with a Leica DFC450C using Leica Application Suite Version 4.4 software. The results of morphohistochemical studies have shown that in acute poisoning of dogs with isoniazid in the heart prevailed acute disorders of the vascular circulation, manifested by a sharp expansion and destruction of the walls of the venous vessels, plasmorrhagia, microtromb of the capillaries and spasm of the arterioles, which led to the development of swelling, caused acute decrease of protein synthesation function of muscle fibers and dystrophic-necrobiotic changes of cardiomyocytes. It was noted, in the lungs of dogs on the background of acute congestive hyperemia, diapedesis of erythrocytes and accumulation of transudate in the lumen of the alveoli, foci of emphysema and bronchiectasis with rupture of the epithelial layer of the mucous membrane, elastic skeleton and muscular tubules of bronchial tubules that indicated the violation of gas exchange and the development of anoxemia. It is known that spontaneous isoniazid poisoning in dogs leads to an acute course and often fatal consequences. In the comprehensive study of the effects of chemicals on the body, and in particular isoniazid on the body of dogs, toxicological and pathomorphological studies are of great importance. The use of morphological and histochemical methods will reveal some of the mechanisms of intoxication.
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12

Van Roost, Dirk, Christof Thees, Christopher Brenke, Falk Oppel, Peter A. Winkler, and Johannes Schramm. "Pseudohypoxic Brain Swelling: A Newly Defined Complication after Uneventful Brain Surgery, Probably Related to Suction Drainage." Neurosurgery 53, no. 6 (December 1, 2003): 1315–27. http://dx.doi.org/10.1227/01.neu.0000093498.08913.9e.

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Abstract OBJECTIVE This is the first description of a severe and sometimes fatal complication after uneventful intracranial surgery. The clinical presentation and imaging features mimic those of global cerebral hypoxia. Extensive investigations were performed to discover the pathogenesis. METHODS Seventeen cases of pseudohypoxic brain swelling (PHBS) were collected from our institution and from various other neurosurgical departments and were studied for common features. PHBS can occur in a mild, moderate, or severe degree. It is characterized by a very early postoperative onset of clinical deterioration (clouded or lost consciousness and pupillary abnormalities), in association with typical bilateral computed tomographic or magnetic resonance imaging changes (hypodensities or altered intensities in the basal ganglia and/or thalamus). The following variables were considered: age, primary pathological lesion and intracranial location, previous cranial surgery, anesthetic risk, type of anesthesia, approach and duration of surgery, intraoperative observations, technical monitoring results, and blood gas analyses. The results of postoperative computed tomography and various other imaging studies, intracranial pressure measurements, transcranial Doppler sonography, toxicological analyses, brain and muscle biopsies, and autopsies were also considered in the investigation. Several countermeasures were instituted and evaluated. RESULTS Anoxemic and ischemic hypoxia was excluded as a cause of PHBS. No evidence was found for inhibition of the respiratory chain, mitochondriopathy, poisoning, or adverse effects of drugs. CONCLUSION Indications of intracranial hypotension, induced by suction drainage, being the main pathomechanism of PHBS are discussed. A serious warning is issued regarding the use of suction drainage after intracranial surgery.
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13

"Earlier Investigations Regarding the Anoxemia Test." Acta Medica Scandinavica 128, S195 (April 24, 2009): 14–26. http://dx.doi.org/10.1111/j.0954-6820.1947.tb15089.x.

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14

"A Critical View of the Anoxemia Test." Acta Medica Scandinavica 128, S195 (April 24, 2009): 31–38. http://dx.doi.org/10.1111/j.0954-6820.1947.tb15091.x.

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15

"Discussion of the Possibilities of Improving the Anoxemia Test." Acta Medica Scandinavica 128, S195 (April 24, 2009): 39–41. http://dx.doi.org/10.1111/j.0954-6820.1947.tb15092.x.

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16

"Own Investigations. Anoxemia Tests with Addition of Carbon Dioxide to the Inspired Gas." Acta Medica Scandinavica 128, S195 (April 24, 2009): 56–81. http://dx.doi.org/10.1111/j.0954-6820.1947.tb15094.x.

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17

Dean, Jay B. "I. Preparing for a Physiological Air War: Survey No. 1 by the Committee on Aviation Medicine of Aero Medical Research Facilities Available in America (12 Nov – 1 Dec 1940)." FASEB Journal 31, S1 (April 2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.1003.1.

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At its first meeting, 23 Oct 1940, the Committee on Aviation Medicine (CAM) was tasked with making “…a survey of the present status of the medical and physiological problems pertaining to aviation…[and to] advise regarding the correlation and coordination of such research undertakings as are going forward in various government labs and flying fields, as well as in civilian labs and commercial aviation units. In addition the Committee should suggest the inauguration and development of new studies and investigative projects pertaining to the biological aspects of aviation and necessary to the national defense.” The CAM was comprised of Dr. E.F. DuBois, CAM Chairman (Cornell U) and members Drs. C.K. Drinker (Harvard U), J.F. Fulton (Yale U), W.R. Miles (Yale U) and E.M. Landis (U Va). The CAM and two USN liaison officers (Cdr. J.R. Poppen, Capt. L.E. Griffis) traveled by air from Washington D.C. to eight sites during 12 Nov – 1 Dec 1940: Langley Field; Norfolk Naval Air Base; Guantanamo Bay, Cuba and the Aircraft Carriers Wasp & Ranger; the Pensacola Naval Air Station and School of Aviation Medicine; San Diego Naval Air Base, and the Carrier Saratoga; Wright Field, Aero Medical Research Unit, Dayton; and the Banting Institute and Eglinton Labs, Toronto, Canada. The CAM's report to the National Research Council (NAS Archives: CAM Bulletin, pp. 52–96) made 20 recommendations to improve preparedness for a high‐altitude, high‐speed air war. They recognized that to date, aero medical research had lagged far behind development of aircraft. The limiting factor in flight operations was the pilot's physiology. Larger and better labs were needed at Wright Field, Randolph Field, Pensacola and Washington. Aero medical research should be expedited in civilian labs through immediate federal funding. Research projects the CAM deemed of urgent importance included: development of a suitable O2 breathing apparatus and pressurized aircraft cabins, with more studies in altitude chambers and planes at high‐altitude; mitigation strategies for relief from flyer's aeroembolism and black‐out from G‐forces during acceleration; effects of anoxemia on production of cerebral edema and increased cerebrospinal fluid pressure; effects of protracted breathing of 100% O2; psychological tests; fatigue; critical assessment of the Schneider test as a predictor of human efficiency; usefulness of the EEG in aviation medicine; studies of visual problems; problems of adequate clothing, particularly electrically‐heated clothing; and general studies of recreational and rest facilities at air stations. By 1942, the CAM had expanded into 7 subcommittees to oversee America's growing aero medical research program: Advisory Commission A (on the west coast near aircraft factories) to the CAM in Washington, Acceleration, Oxygen & Anoxia, Decompression Sickness, Visual Problems, Clothing, and Motion Sickness. Other general fields included adrenal physiology, the crash project, explosive decompression and pressure‐cabin aircraft, flying fatigue, injury to flying personnel by anti‐aircraft blasts, first aid aloft, rehabilitation program, and problem of securing information from operation squadrons.Support or Funding InformationUSF
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