Academic literature on the topic 'Anion carrier'

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Journal articles on the topic "Anion carrier"

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Tosolini, Massimo, Paolo Pengo, and Paolo Tecilla. "Biological Activity of Trans-Membrane Anion Carriers." Current Medicinal Chemistry 25, no. 30 (September 27, 2018): 3560–76. http://dx.doi.org/10.2174/0929867325666180309113222.

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Natural and synthetic anionophores promote the trans-membrane transport of anions such as chloride and bicarbonate. This process may alter cellular homeostasis with possible effects on internal ions concentration and pH levels triggering several and diverse biological effects. In this article, an overview of the recent results on the study of aniontransporters, mainly acting with a carrier-type mechanism, is given with emphasis on the structure/activity relationship and on their biological activity as antibiotic and anticancer agents and in the development of new drugs for treating conditions derived from dysregulation of natural anion channels.
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Simchowitz, L., R. Ratzlaff, and P. De Weer. "Anion/anion exchange in human neutrophils." Journal of General Physiology 88, no. 2 (August 1, 1986): 195–217. http://dx.doi.org/10.1085/jgp.88.2.195.

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Of the total one-way chloride fluxes (approximately 1.4 meq/liter cell water X min) in steady state human polymorphonuclear leukocytes bathed in 148 mM Cl media, approximately 70% behaves as self-exchange mediated by a nonselective anion carrier that is not inhibited by stilbene disulfonates. Five properties of this carrier-mediated exchange were investigated: substrate saturation is seen with respect to 36Cl influx as a function of the external Cl concentration [for normal-Cl cells, the apparent Km(Cl) is approximately 22 mM when Cl replaces para-amino-hippurate (PAH) and approximately 5 mM when Cl replaces glucuronate], and with respect to 36Cl efflux as a function of the concentration of internal Cl replacing PAH [apparent Km(Cl) congruent to 35 mM for cells bathed in 148 mM Cl]; there is trans stimulation of 36Cl influx by internal Cl (replacing PAH) with an apparent Km(Cl) congruent to 35 mM, and of 36Cl efflux by external Cl with an apparent Km(Cl) congruent to 22 mM (Cl replacing PAH) or approximately 5 mM (Cl replacing glucuronate); there is substrate competition between Cl and PAH, but the carrier appears devoid of affinity for glucuronate; influxes and effluxes mediated by the carrier are subject to competitive inhibition by extracellular alpha-cyano-4-hydroxycinnamate (CHC), with an apparent Ki congruent to 9 mM in Cl medium or approximately 1 mM in PAH medium (transport of the inhibitor itself is very slow); and internal Cl and external Cl or PAH undergo 1:1 countertransport, which is CHC sensitive. A simple equilibrium-competition model is proposed that accounts for all the extracellular ligand interactions presented for normal-Cl cells. Least-squares values of the carrier's true Michaelis constants for extracellular Cl, PAH, and CHC are 5.03 +/- 0.83, 50.3 +/- 14.9, and 0.29 +/- 0.09 mM, respectively.
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Keihankhadiv, Shadi, and Dorota Neugebauer. "Synthesis and Characterization of Linear Copolymers Based on Pharmaceutically Functionalized Monomeric Choline Ionic Liquid for Delivery of p-Aminosalicylate." Pharmaceutics 15, no. 3 (March 7, 2023): 860. http://dx.doi.org/10.3390/pharmaceutics15030860.

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Bioactive linear poly(ionic liquid)s (PIL) were designed as carriers in drug delivery systems (DDS). Their synthesis was based on a monomeric ionic liquid (MIL) with a relevant pharmaceutical anion to create therapeutically functionalized monomers, which further can be used in the controlled atom transfer radical polymerization (ATRP). The presence of chloride counterions in the quaternary ammonium groups of choline MIL, e.g., [2-(methacryloyloxy)ethyl]trimethyl-ammonium chloride (ChMACl), was stimulated to undergo the anion exchange with p-aminosalicylate sodium salt (NaPAS) as the source of the pharmaceutical anion with antibacterial activity. The resultant [2-(methacryloyloxy)ethyl]trimethylammonium p-aminosalicylate (ChMAPAS) was copolymerized to attain the well-defined linear choline-based copolymers with various contents of PAS anions (24–42%), which were regulated by the initial ratio of ChMAPAS to MMA and conversion degree. The length of polymeric chains was evaluated by the total monomer conversion (31–66%) yielding degree of polymerization (DPn = 133–272). Depending on the polymer carrier composition, PAS anions were exchanged by 60–100% within 1 h, 80–100% within 4 h, and completely after 24 h by phosphate anions in PBS imitating a physiological fluid.
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Fortenberry, R. C. "Theoretical Electronic and Rovibrational Studies for Anions of Interest to the DIBs." Proceedings of the International Astronomical Union 9, S297 (May 2013): 344–48. http://dx.doi.org/10.1017/s1743921313016098.

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AbstractThe dipole-bound excited state of the methylene nitrile anion (CH2CN−) has been suggested as a candidate carrier for a diffuse interstellar band (DIB) at 803.8 nm. Its corresponding radical has been detected in the interstellar medium (ISM), making the existence for the anion possible. This work applies state-of-the-art ab initio methods such as coupled cluster theory to reproduce accurately the electronic excitations for CH2CN− and the similar methylene enolate anion, CH2CHO−. This same approach has been employed to indicate that 19 other anions may possess electronically excited states, five of which are valence in nature. Concurrently, in order to assist in the detection of these anions in the ISM, work has also been directed towards predicting vibrational frequencies and spectroscopic constants for these anions through the use of quartic force fields (QFFs). Theoretical rovibrational work on anions has thus far included studies of CH2CN−, C3H−, and is currently ongoing for similar systems.
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Buttner, B., and D. Beyersmann. "Modification of the erythrocyte anion carrier by chromate." Xenobiotica 15, no. 8-9 (January 1985): 735–41. http://dx.doi.org/10.3109/00498258509047435.

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Pedersen, Peter L. "An introduction to the mitochondrial anion carrier family." Journal of Bioenergetics and Biomembranes 25, no. 5 (October 1993): 431–34. http://dx.doi.org/10.1007/bf01108400.

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Pritchard, J. B., and D. S. Miller. "Comparative insights into the mechanisms of renal organic anion and cation secretion." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 261, no. 6 (December 1, 1991): R1329—R1340. http://dx.doi.org/10.1152/ajpregu.1991.261.6.r1329.

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Comparative models have played a major role in defining the mechanisms that enable vertebrate proximal tubules to transport organic anions and cations from the peritubular interstitium to the urine. The unique advantages of these models and their contributions to our understanding of organic anion and cation transport mechanisms are summarized here. Recent studies of the organic anion transport system suggest that transport is coupled to metabolic energy via indirect coupling to the sodium gradient. Organic anions enter the cell across the basolateral membrane in exchange for alpha-ketoglutarate (alpha-KG), and the alpha-KG is returned to the interior via Na-alpha-KG cotransport. Indirect coupling to Na has been demonstrated in both isolated membranes and intact renal epithelial cells of species ranging from marine crustaceans to mammals. This mechanism was shown to drive not only cellular accumulation but also secretory transepithelial fluxes of organic anions. Luminal exit of secreted organic anions appears to be carrier mediated but is, at present, poorly understood, with mediated potential-driven efflux and anion exchange-driven efflux implicated in some species. As for organic anions, the renal clearance of some organic cations approaches the renal plasma flow. Although there is considerable variation in the handling of specific substrates between species, the basic properties of organic cation transport include carrier-mediated potential-driven uptake at the basolateral membrane, intracellular sequestration that reduces the free concentration of the cation, and luminal exit by organic cation-proton exchange. Reabsorptive transport is also observed for some organic cations, but its mechanisms and driving forces are not well understood.
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Restrepo, D., B. L. Cronise, R. B. Snyder, L. J. Spinelli, and P. A. Knauf. "Kinetics of DIDS inhibition of HL-60 cell anion exchange rules out ping-pong model with slippage." American Journal of Physiology-Cell Physiology 260, no. 3 (March 1, 1991): C535—C544. http://dx.doi.org/10.1152/ajpcell.1991.260.3.c535.

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According to the ping-pong model of band 3-mediated anion exchange, the transport protein has a single transport site, which can exist in either an inward-facing or an outward-facing conformation. Anions bind to these unloaded forms of the carrier, and translocation takes place only when a suitable anion is bound to the transport site. In a previous paper [Am. J. Physiol. 257 (Cell Physiol. 26): C520-C527, 1989], we had shown that the substrate kinetics of Cl-Cl exchange in the promyelocytic HL-60 cell cannot be explained by this simple ping-pong model of anion exchange but is consistent with a simultaneous model according to which both extracellular and intracellular anions must bind before simultaneous translocation can take place. In the present paper we show that external 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) inhibits anion exchange in HL-60 cells by competing with Cl- for binding to the outward-facing transport site. Furthermore, there is a linear dependence of the slope of the Dixon plot for inhibition by DIDS on the reciprocal of the intracellular Cl- concentration. This result clearly rules out a simple ping-pong scheme. In addition, the data also rule out a ping-pong model in which some translocation of the unloaded carrier is allowed (ping-pong model with slippage). The observed inhibition kinetics can be modeled by a simultaneous model of Cl-Cl exchange with competitive inhibition by DIDS.
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Elgavish, A., J. J. Wille, F. Rahemtulla, and L. Debro. "Carrier-mediated sulfate transport in human ureteral epithelial cells cultured in serum-free medium." American Journal of Physiology-Cell Physiology 261, no. 5 (November 1, 1991): C916—C926. http://dx.doi.org/10.1152/ajpcell.1991.261.5.c916.

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Sulfate transport studies were carried out in secondary cultures of epithelial cells isolated from the human ureter. Results demonstrate the presence of carrier-mediated SO4(2-) transport as supported by three lines of evidence: 1) saturation kinetics, 2) substrate specificity, and 3) inhibition by the anion transport inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS). The DIDS-insensitive component of SO4(2-) transport was markedly lower than the DIDS-sensitive component and was not affected by changes in extracellular pH (pHo) or Cl- concentration. The mechanism of this DIDS-insensitive component is not clear. The DIDS-sensitive component of SO4(2-) uptake was a saturable function of the extracellular sulfate concentration ([SO4(2-)]o). Increasing the extracellular chloride concentration ([Cl-]o) inhibited DIDS-sensitive SO4(2-) uptake competitively. Taken together with the fact that increasing [Cl-]o stimulated SO4(2-) efflux, these results suggest that SO4(2-) uptake in uroepithelial cells occurs via SO4(2-)-Cl- anion exchange. Cis-inhibition studies with a variety of anions indicate that this anion-exchange system may be shared by S2O3(2-) and MoO4(2-) but not by NO3- and H2PO4-. SO4(2-) uptake was stimulated at decreasing pHo with a pK approximately 7.4. Decreasing pHo from 7 to 6 lowered the apparent Michaelis constant significantly but had no significant effect on kcat, suggesting that protons may increase the affinity of the SO4(2-) transporter for SO4(2-). SO4(2-) efflux was inhibited at low pHo and was stimulated by increasing [Cl-]o. This study is the first to demonstrate an ion transport process in epithelial cell cultures isolated from the human ureter. In contrast to epithelial cells from the upper urinary tract, no Na(+)-dependent SO4(2-) transport could be demonstrated in these lower urinary tract epithelial cells. In conclusion, the major mechanism for SO4(2-) transport in ureteral epithelial cells is a carrier-mediated, DIDS-sensitive, pHo-sensitive SO4(2-)/Cl- anion-exchange mechanism. These studies suggest that varying [SO4(2-)]o and [Cl-]o or pHo in the ureteral lumen will affect SO4(2-) influx and efflux and may influence the size of the intracellular pool of SO4(2-) available for macromolecular sulfation in these cells.
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Chesher, D. A., P. A. Christensen, and A. Hamnett. "Anion movement and carrier type in polypyrrole/dodecyl sulfate." Journal of the Chemical Society, Faraday Transactions 89, no. 2 (1993): 303. http://dx.doi.org/10.1039/ft9938900303.

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Dissertations / Theses on the topic "Anion carrier"

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Lohi, Hannes. "The human solute carrier 26 family of anion exchangers." Helsinki : University of Helsinki, 2002. http://ethesis.helsinki.fi/julkaisut/laa/haart/vk/lohi/.

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Yu, Katayama. "Towards the realization of anion-exchange membrane fuel cell technology: potential of hydrogen-carrier utilization." Kyoto University, 2017. http://hdl.handle.net/2433/227631.

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McManus, Kirk James. "Molecular variation in the solute carrier family 4, anion exchanger member 1 gene, characterization of three low-incidence erythroid antigens." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ51766.pdf.

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Spooner, Michael. "Anions and the bilayer : structural and mechanistic studies towards synthetic anion carriers for therapeutic applications." Thesis, University of Southampton, 2017. https://eprints.soton.ac.uk/410302/.

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Synthetic transmembrane anion transporters have attracted a great deal of interest due to their potential as therapeutic agents for the treatment of channelopathies such as cystic fibrosis or in the treatment of cancer. Despite a great deal of progress in the field over recent years, there are currently several hurdles that need to be overcome before anionophores become genuine therapeutic candidates. These include knowledge of how carriers behave in more cell-like bilayer systems, what molecular properties govern the rate determining step of the transport process and issues with solubility and deliverability. This thesis aims to explore some of these areas to help overcome some of these future barriers. The effect of lipid environment on the transport ability of a series of alkyl-substituted thioureas was investigated. The series covered a wide range of lipophilicity, to determine whether the optimum lipophilic range varied depending on the composition of the bilayer. Despite the different lipids appearing to modulate the overall transport rate, the relative order of the transporter efficacy appeared unaffected. Data is also presented demonstrating the use of dynamic covalent chemistry to generate an active transporter molecule in situ within the membrane. The compound formed by DCC was observed by measuring its transport response from vesicle experiments after the addition of two precursors (which do not facilitate transport alone) to the membrane. Comparison of the transport ability of the pre-formed compound and the rate of the DCC reaction measured by NMR spectroscopy gave insight into the balance required between these two factors in the design of these compounds. Finally, the effect of the fluorination of alkyl chains in tripodal tris-thiourea receptors was explored. Vesicle assays with and without accompanying protonophores to couple to the transport process were carried out to determine the mechanism of the transport process and discover whether fluorination had any effect on the selectivity of the transporter molecules. The activity of the compounds in FRT-YFP cell assays was also determined and comparison with the vesicle data gave insights into the vesicle tests required to accurately predict the transporters’ efficacy in cell epithelia.
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Ahlin, Gustav. "In vitro and in silico prediction of drug-drug interactions with transport proteins." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-107492.

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Ford, Debra Ann. "Enhanced anion transport using some expanded porphyrins as carriers." Thesis, Springfield, Virginia: Available from National Technical Information Service, 1991. http://hdl.handle.net/10945/28166.

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Haynes, Cally J. E. "The design of synthetic transmembrane carriers for anions." Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/206159/.

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This thesis reports a number of novel receptors found to facilitate the transmembrane transport of anions in synthetic vesicle systems. A series of structurally simple thioureas were found to function as efficient Cl-/NO3- and Cl-/HCO3- antiporters while the corresponding ureas were inactive. Of these receptors, a simple indolylthiourea was found to be an extremely potent transporter which could function at concentrations as low as 1:25 000 (molar ratio with respect to lipid). Subsequently, a series of bipodal bis-alkyl-indolylureas were found to mediate Cl-/NO3 - antiport, with the observed anion transport found to be highly dependent on the length of the central alkyl chain bridging the two indolylurea moieties. The mechanism of transport and the structure-activity relationships were extensively investigated using a wide range of vesicle-based techniques. The solution phase anion binding properties of these receptors was found to be complex as a result of the flexibility of the receptors and the distance between the binding sites. The binding of dihydrogen phosphate and oxalate by receptors in this series was also demonstrated in the solid state. A series of bipodal bis-phenylthioureas were also found to mediate Cl-/NO3 - and Cl-/HCO3- antiport which was again found to be dependent on the alkyl chain length. The effect of substituent variation on transport activity was also examined, while the solution phase binding properties were found to be similarly complex to the bis-indolylurea receptors. The anion transport activity of a series of strapped calix[4]pyrroles provided by J. L. Sessler and C.-H. Lee was investigated. It was found that the straps were able to encourage transport mechanisms not exhibited by the parent macrocycle, while a series of control compounds were inactive
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Lopez, Carrera Henry Lauro [Verfasser], and Matthias [Akademischer Betreuer] Weidemüller. "Sympathetic cooling and rotational quenching of molecular anions in a hybrid atom ion trap / Henry Lauro Lopez Carrera ; Betreuer: Matthias Weidemüller." Heidelberg : Universitätsbibliothek Heidelberg, 2018. http://d-nb.info/1177149214/34.

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Lopez, Carrera Henry Lauro Verfasser], and Matthias [Akademischer Betreuer] [Weidemüller. "Sympathetic cooling and rotational quenching of molecular anions in a hybrid atom ion trap / Henry Lauro Lopez Carrera ; Betreuer: Matthias Weidemüller." Heidelberg : Universitätsbibliothek Heidelberg, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:16-heidok-252258.

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"Identification and characterization of a novel human liver-specific organic anion transporter (SLC22A7)." 2000. http://library.cuhk.edu.hk/record=b5890304.

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Siu Shu Shun.
Thesis (M.Phil.)--Chinese University of Hong Kong, 2000.
Includes bibliographical references (leaves 100-106).
Abstracts in English and Chinese.
Acknowledgements --- p.i
Contents --- p.ii
Abstract / 摘要 --- p.iv
Abbreviations --- p.vi
List of figures --- p.vii
List of tables --- p.x
Chapter Chapter 1: --- Introduction
Chapter 1.1 --- "Human EST sequencing project, the role and goal" --- p.1
Chapter 1.2 --- Human liver cDNA sequencing --- p.2
Chapter 1.3 --- The role of membrane-associated proteins in hepatocellular functions --- p.3
Chapter 1.3.1 --- Outline of the liver function --- p.3
Chapter 1.3.2 --- Basic structure of hepatocyte --- p.4
Chapter 1.3.3 --- Category of membrane associated proteins --- p.5
Chapter 1.4 --- Identification of human OAT2 gene --- p.7
Chapter 1.5 --- The multispecific transporter family --- p.8
Chapter 1.5.1 --- Classification --- p.8
Chapter 1.5.2 --- The human OAT family --- p.9
Chapter 1.6 --- The characteristics of rat multispecific OAT2 --- p.11
Chapter 1.7 --- Clinical significance of organic anion transport proteins --- p.14
Chapter Chapter 2: --- Materials and Methods
Chapter 2.1 --- Human liver EST sequencing project --- p.16
Chapter 2.1.1 --- Plating out the adult human liver phage library --- p.16
Chapter 2.1.2 --- PCR detection and amplification of the cDNA clone --- p.17
Chapter 2.1.3 --- Automatic cDNA sequencing --- p.18
Chapter 2.2 --- Cloning of hOAT2 gene into TA cloning vector pT-Adv --- p.19
Chapter 2.2.1 --- Amplification of hOAT2 by PCR --- p.19
Chapter 2.2.2 --- Ligation reaction --- p.19
Chapter 2.2.3 --- Transformation of recombinant plasmid into competent cells --- p.20
Chapter 2.3 --- Sequence analysis and structural prediction --- p.20
Chapter 2.4 --- Cloning of the hOAT2 gene into the pQE30 expression vector --- p.21
Chapter 2.4.1 --- PCR amplification and restriction endonuclease cutting --- p.21
Chapter 2.4.2 --- Gene clean --- p.22
Chapter 2.4.3 --- Preparation of bacterial competent cells --- p.23
Chapter 2.5 --- Small scale synthesis of plasmid DNA --- p.24
Chapter 2.6 --- Large scale synthesis of plasmid DNA --- p.25
Chapter 2.7 --- Cloning of the hOAT2 gene into the pSecTag2B mammalian expression vector --- p.26
Chapter 2.8 --- Cloning of the hOAT2 gene into the pEGFP-C2 fluorescent vector --- p.27
Chapter 2.8.1 --- Tissue culture and transfection --- p.27
Chapter 2.8.2 --- Fluorescence microscopy examination --- p.28
Chapter 2.9 --- Chromosomal mapping of the hOAT2 gene --- p.29
Chapter 2.9.1 --- Somatic cell hybrids mapping --- p.29
Chapter 2.9.2 --- Radiation hybrids mapping --- p.29
Chapter 2.10 --- Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) --- p.30
Chapter 2.11 --- Western hybridization --- p.32
Chapter 2.11.1 --- Preparation of anti-hOAT2 antibodies --- p.32
Chapter 2.11.1.1 --- Synthetic peptide conjugation --- p.32
Chapter 2.11.1.2 --- Immunizing rabbit polyclonal antibodies for human OAT2 --- p.32
Chapter 2.11.1.3 --- Purification of the rabbit polyclonal IgG antibodies --- p.33
Chapter 2.11.2 --- Western blot analysis --- p.33
Chapter 2.11.2.1 --- Protein isolation from rat liver --- p.33
Chapter 2.11.2.2 --- Prote in preparation from cell lysate --- p.34
Chapter 2.11.2.3 --- Quantitation of total proteins by Bradford protein assay --- p.35
Chapter 2.11.2.4 --- Blotting and hybridization --- p.35
Chapter Chapter 3: --- Results
Chapter 3.1 --- Catalogue of the 500 liver ESTs --- p.37
Chapter 3.2 --- Nomenclature of human NLT gene --- p.47
Chapter 3.3 --- Cloning and characterization of the hOAT2 sequence --- p.48
Chapter 3.3.1 --- Isolation of hOAT2 cDNA from human liver cDNA library --- p.48
Chapter 3.3.2 --- The primary and secondary structural analysis of hOAT2 --- p.53
Chapter 3.3.3 --- Motif search and prediction --- p.61
Chapter 3.3.4 --- Homology alignment --- p.64
Chapter 3.4 --- Chromosomal mapping of hOAT2 gene --- p.67
Chapter 3.4.1 --- Somatic cell hybrid mapping of hOA T2 gene --- p.67
Chapter 3.4.2 --- Radiation hybrid mapping of hOA T2 gene --- p.69
Chapter 3.4.3 --- Identification of partial human genomic sequence --- p.73
Chapter 3.5 --- Detection of the hOAT2 gene expression in human tissues by RT- PCR assay --- p.76
Chapter 3.6 --- Detection of subcellular localization of hOAT2 protein by conjugating fluorescence protein --- p.81
Chapter 3.7 --- Immunodetection of protein extracts from cultured cells --- p.83
Chapter Chapter 4: --- Discussion
Chapter 4.1 --- Characterization of the hepatocellular ESTs --- p.85
Chapter 4.1.1 --- Classification and frequency distribution of the 500 ESTs --- p.85
Chapter 4.1.2 --- The expression pattern of membrane associated proteins --- p.87
Chapter 4.2 --- Tissue distribution and expression profiles of hOAT2 --- p.88
Chapter 4.3 --- HOAT2 in fetal development --- p.89
Chapter 4.4 --- Predicting the topology of membrane proteins --- p.90
Chapter 4.5 --- Chromosomal mapping of human OAT2 --- p.91
Chapter 4.6 --- Possible functions of hOAT2 --- p.93
Chapter 4.6.1 --- Hepato-renal relation --- p.93
Chapter 4.6.2 --- Substrate diversity --- p.95
Chapter 4.7 --- Fluorescence detection for subcellular localization --- p.96
Chapter 4.8 --- Conclusion --- p.97
Chapter 4.9 --- Further aspects --- p.99
References --- p.100
Appendix --- p.107
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Books on the topic "Anion carrier"

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A, Azzi, Instytut Biologii Doświadczalnej im. M. Nenckiego., and International Conference on Anion Carriers of Mitochondrial Membranes (1988 : Zakopane, Poland), eds. Anion carriers of mitochondrial membranes. Berlin: Springer-Verlag, 1989.

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Symposium on Epithelial Anion Transport in Health and Disease: the Role of the SLC26 Transporters Family (2005 Novartis Foundation). Epithelial Anion Transport in Health and Disease. New York: John Wiley & Sons, Ltd., 2006.

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Symposium on Epithelial Anion Transport in Health and Disease: the Role of the SLC26 Transporters Family (2005 Novartis Foundation). Epithelial anion transport in health and disease: The role of the SLC26 transporters family. Chichester, U.K: John Wiley & Sons, 2006.

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International, Meeting on Anion Transport Protein of the Red Blood Cell Membrane as well as Kidney and Diverse Cells (1989 Fukuoka-shi Japan). Anion transport protein of the red blood cell membrane: Proceedings of the International Meeting on Anion Transport Protein of the Red Blood Cell Membrane as well as Kidney and Diverse Cells, Fukuoka, 1-3 May 1989. Amsterdam: Elsevier, 1989.

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Azzi, Angelo, Katarzyna A. Nałęz, Maciej J. Nałęcz, and Lech Wojtczak, eds. Anion Carriers of Mitochondrial Membranes. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3.

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Ford, Debra Ann. Enhanced anion transport using some expanded porphyrins as carriers. Springfield, Va: Available from the National Technical Information Service, 1991.

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Zhao, Xiaogang. Synthesis and reactivity of organocopper reagents using a new radical anion electron carrier. 1996.

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The Band 3 proteins: Anion transporters, binding proteins, and senescent antigens. Amsterdam: Elsevier, 1992.

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Passow, Hermann, and Ernst Bamberg. The Band 3 Proteins: Anion Transporters, Binding Proteins, and Senescent Antigenes (Progress in Cell Research). Elsevier Publishing Company, 1992.

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Azzi, Angelo, and Hansjakob Mattern. Anion Carriers of Mitochondrial Membranes. Springer, 2011.

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Book chapters on the topic "Anion carrier"

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Nałçcz, Katarzyna A., Reinhard Bolli, Lech Wojtczak, and Angelo Azzi. "Purification of the Monocarboxylate Carrier by Affinity Chromatography." In Anion Carriers of Mitochondrial Membranes, 45–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_4.

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Klingenberg, M. "Molecular Aspects of the Adenine Nucleotide Carrier from Mitochondria." In Anion Carriers of Mitochondrial Membranes, 169–81. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_14.

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Ligeti, Erzsébet, Edgár Brázda, and Attila Fonyó. "Mitochondrial Phosphate Carrier: Relation of its SH Groups to Oligomeric Organization." In Anion Carriers of Mitochondrial Membranes, 123–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_10.

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Nałęcz, Maciej J., Adam Szewczyk, Clemens Broger, Lech Wojtczak, and Angelo Azzi. "Isolation and Functional Reconstitution of the Dicarboxylate Carrier from Bovine Liver Mitochondria." In Anion Carriers of Mitochondrial Membranes, 71–85. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_6.

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Szewczyk, Adam, and Maciej J. NaŁĘcz. "New Photoaffinity Derivatives of Malonate and Succinate to Study Mitochondrial Carrier Systems." In Anion Carriers of Mitochondrial Membranes, 87–97. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_7.

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Brandolin, G., F. Boulay, P. Dalbon, M. Block, I. Gauche, and P. V. Vignais. "Immunological and Enzymatic Approaches of the Orientation of the Membrane Bound ADP/ATP Carrier." In Anion Carriers of Mitochondrial Membranes, 147–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_12.

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Claeys, D., M. Müller, and A. Azzi. "Purification and Reconstitution of the 2-Oxoglutarate Carrier from Bovine Heart and Liver Mitochondria." In Anion Carriers of Mitochondrial Membranes, 17–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_2.

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Mazat, Jean-Pierre, Eric Jean-Bart, Michel Rigoulet, Christine Reder, and Bernard Guerin. "Control of Oxidative Phosphorylation in Yeast Mitochondria: The Role of Phosphate Carrier and pH." In Anion Carriers of Mitochondrial Membranes, 327–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_27.

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Vignais, P. V., G. Brandolin, F. Boulay, P. Dalbon, M. R. Block, and I. Gauche. "Recent Developments in the Study of the Conformational States and the Nucleotide Binding Sites of the ADP/ATP Carrier." In Anion Carriers of Mitochondrial Membranes, 133–46. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74539-3_11.

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Shcheynikov, Nikolay, Ehud Ohana, and Shmuel Muallem. "Properties and Function of the Solute Carrier 26 Family of Anion Transporters." In Ion Channels and Transporters of Epithelia in Health and Disease, 465–89. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-3366-2_14.

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Conference papers on the topic "Anion carrier"

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Anraku, Sohtaro, Kazuya Morimoto, Tsutomu Sato, and Tetsuro Yoneda. "Formation of Secondary Minerals and Uptake of Various Anions Under Naturally-Occurring Hyperalkaline Conditions in Oman." In ASME 2009 12th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2009. http://dx.doi.org/10.1115/icem2009-16344.

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In Japanese transuranic (TRU) waste disposal facilities, 129I is the most important key nuclide for the long-term safety assessment. Thus, the Kd values of I to natural minerals are important factor in the safety assessment. However, the degradation of cement materials in the repositories can produce high pH pore fluid which can affect the anion transport behavior. Therefore, it is necessary to understand the behavior of anions such as I− under the hyperalkaline conditions. The natural hyperalkaline spring water (pH>11) in the Oman ophiolite is known to be generated from the partly serpentinized peridotites. The spring water is characteristically hyperalkaline, reducing, low-Mg, Si and HCO3−, and high-Ca, while the river water is moderately alkaline, oxidizing, high-Mg and HCO3−. The mixing of these spring and river water resulted in the formation of secondary minerals. In the present study, the naturally occurring hyperalkaline conditions near the springs in Oman were used as natural analogue for the interaction between cement pore fluid and natural Mg-HCO3− groundwater. The present aim of this paper is to examine the conditions of secondary mineral formation and the anion uptake capacity of these mineral in this system. Water and precipitate samples were collected from the different locations around the spring vent to identify the effect of mixing ratios between spring and river water on mineral composition and water-mineral distribution coefficient of various anions. On-site synthesis was also carried out to support these data quantitatively. Aragonite was observed in all precipitates, while calcite, brucite and Mg-Al hydrotalcite-like compounds (HTlc) were also determined in some samples. Calcite was observed only closed to the springs. At locations far from the springs, calcite formation was inhibited due to high-Mg fluid from river water. Brucite was observed from the springs with relatively low-Al concentration and HTlc was the opposite. During the formation of the minerals at the mixing points, HCO3- in the river water was fixed as carbonate minerals such as in aragonite and calcite while H3SiO4− in the river water was dominantly fixed into interlayers and surfaces of HTlc. Iodine in spring and river water was mainly fixed in aragonite. Therefore, the uptake I− by secondary minerals can be expected at hyperalkaline conditions as observed at Oman hyperalkaline springs.
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Shrivastava, Megha, Abhijit Hazarika, Matthew C. Beard, and K. V. Adarsh. "Polaron protected long-lived hot carriers in mixed cation and anion perovskite nanocrystals." In CLEO: Applications and Technology. Washington, D.C.: OSA, 2020. http://dx.doi.org/10.1364/cleo_at.2020.jtu2b.1.

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Huppert, D., and E. Pines. "Picosecond Dynamics of Proton-Anion Ion Pair Geminate Recombination." In International Conference on Ultrafast Phenomena. Washington, D.C.: Optica Publishing Group, 1986. http://dx.doi.org/10.1364/up.1986.mc7.

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Charge separation is induced in solutions of many chemical and biochemical systems by light absorption. The primary step in these reactions is either an electron or a proton transfer from a parent molecule to a suitable acceptor. The solvated ion pairs which are produced can either geminately recombine or separate by diffusion. Geminate recombination was recognized to be extremely important in radiation induced electron-cation ion pair generation [1]. As for proton transfer reactions, much less attention has been paid to this phenomenon mainly because of two reasons. The first reason is that proton transfer reactions are usually being carried in aqueous solutions where the coulombic attraction is very efficiently screened. In contrast, electron transfer reactions are usually being carried in hydrocarbon solutions where the coulombic screening is much less effective. The second and less obvious reason is that geminate electron-excited cation recombination usually quenches the excited state where in many cases proton transfer to an excited anion does not quench the anion [2]. As a result, proton transfer reactions are usually bidirectional both in the ground and the excited state [3]. It means that upon recombination the excited parent molecule can undergo redissociation. Thus, the combination of effective coulombic screening by water molecules and consecutive dissociations makes geminate recombination much less apparent in proton transfer reactions than in electron transfer ones.
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Zhou, Yan, and Haifeng Zhang. "Design and Research of Spent Resin Conical Dryer Device." In 2017 25th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/icone25-66008.

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This paper introduced the design and research of spent resin conical dryer which was based on the analysis of the thermal decomposition characteristics of resins. The drying experiment of non-radioactive cation exchange resins and anion exchange resins was also carried out in this study. The result showed that the water content of resins reduced from about 55%(wt) to 8.5%(wt) and the volume reduction ration reached 2.17 with a drying end temperature of 90°C, which preliminarily verified the feasibility of the vacuum drying process and conical dryer device for treating radioactive spent resins.
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Hong, Xu. "Influence of Feedwater TOC on Steam Cation Conductivity." In ASME 2017 Power Conference Joint With ICOPE-17 collocated with the ASME 2017 11th International Conference on Energy Sustainability, the ASME 2017 15th International Conference on Fuel Cell Science, Engineering and Technology, and the ASME 2017 Nuclear Forum. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/power-icope2017-3023.

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The cation conductivity in water-steam cycle has been significantly increased as external heating units presented on trends in large capacity and high parameters. Real test has been carried out to demonstrate the TOC concentration in feedwater has been increased as the external heating increases. The presence of organic acid would significantly reduce the pH of the condensate and result in general corrosion, pitting and environment assisted cracking. For the cogeneration thermal power stations in which make-up water were produced with traditional ion exchange system and Integrated Membrane Technology separately, the main factors affecting cation conductivity of steam are residues of the organics in raw water and dynamic variation about bacterial reproduction in reducing environment, respectively. If gel type anion resin had been replaced with macroporous strong base anion resin, the remaining TOC in traditional ion exchange system could be significantly reduced. And if non-oxidative bactericide had been dosed before or after Ultrahigh Purity Filter, bacteria could be effectively killed. For heat-supply units, the actual rates of makeup water, denote with “N%”, are always more than the design value. So it is very important in this scenario to revise the ceiling values of TOC for makeup water, which should be divided by N, to allow that ceiling value to match the actual rate of makeup water. For drum boilers and once-through boilers which superheated steam pressure are greater than 18.3 MPa, in order to guarantee the cation conductivity (25 °C) values of feed water less than the standard of 0.10 μ S/cm, TOC values in feed water should be under 50μ g/L.
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Seipelt, Agnes. "Digitale Edition und Harmonische Analyse mit MEI von Anton Bruckners Studienbuch." In Jahrestagung der Gesellschaft für Musikforschung 2019. Paderborn und Detmold. Musikwissenschaftliches Seminar der Universität Paderborn und der Hochschule für Musik Detmold, 2020. http://dx.doi.org/10.25366/2020.100.

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The poster shows the results obtained in the project “Digital Music Analysis with the Techniques of the Music Encoding Initiative (MEI) using Anton Bruckner’s compositional studies as an example” (2017 to 2019). On the one hand, the project had the goal of presenting a digital edition of Anton Bruckner’s study book, which he produced during his lessons with Otto Kitzler from 1861 to 1863. An edition of the music in the textbook encoded with MEI and displayed using Verovio and the facsimile can be displayed simultaneously. On the other hand, an automated harmonic analysis of this music was to be designed. For this purpose, keys are recognized using the Krumhansl-Schmuckler algorithm that is based on a resource of pitch classes which are compared with reference values and thus their similarity is calculated. Based on this, chord recognitions are carried out, which are then linked to the keys in the last step and converted to a roman numeral analysis.
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Hayakari, Kohei, Yuki Kanamori, and Yoshimichi Hagiwara. "Molecular Dynamics Analysis on the Interaction Among Water, Cations, Anions and Antifreeze Protein." In 2010 14th International Heat Transfer Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/ihtc14-23196.

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We have carried out molecular dynamics simulation on aqueous solution of winter flounder antifreeze protein with ions or a thin ice layer. It is found that the models of the antifreeze protein and the ions do not affect the motion of water molecules in the case without the ice layer. In the case with the ice layer, the water molecules become less mobile due to the cooling caused by the ice, while the protein becomes more mobile. The protein mobility is consistent with the antifreeze activity of the protein. On the other hand, in the case with the ice layer and the ions, the water molecules become more mobile, and the protein gradually becomes so. This fact is consistent with the cooperative effect of the antifreeze protein and the ions on the lowering of the freezing point.
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Davidson, Jacob D., and N. C. Goulbourne. "Actuation and Charging Characteristics of Ionic Liquid-Ionic Polymer Transducers." In ASME 2010 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2010. http://dx.doi.org/10.1115/smasis2010-3892.

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Ionic polymer transducers (IPTs) are soft sensors and actuators which operate through a coupling of micro-scale chemical, electrical, and mechanical interactions. The use of an ionic liquid as solvent for an IPT has been shown to dramatically increase transducer lifetime in free-air use, while also allowing for higher applied voltages without electrolysis. In this work we model charge transport in an ionic liquid IPT by considering both the cation and anion of the ionic liquid as mobile charge carriers, a phenomenon which is unique to ionic liquid IPTs compared to their water-based counterparts. The electrochemical behavior of the large ionic liquid ions is described by use of a modified Nernst-Planck equation which accounts for steric effects in double layer packing. The method of matched asymptotic expansions is applied to solve the resulting system of equations, and analytical expressions are derived for the nonlinear charge transferred and capacitance of the IPT as a function of the applied voltage. The boundary layer ionic concentration and charge density profiles and the leading order dynamics are also computed for the ionic liquid IPT. A simple equivalent circuit model is constructed in order to facilitate a comparison with experimental results. The implications of these model results in regards to actuation and charging performance characteristics of ionic liquid IPTs are noted.
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Reeves, Carlton J., Sarah Garvey, Pradeep L. Menezes, Mark Dietz, Tien-Chien Jen, and Michael R. Lovell. "Tribological Performance of Environmentally Friendly Ionic Liquid Lubricants." In ASME/STLE 2012 International Joint Tribology Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/ijtc2012-61180.

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Presented in this study is a new class of “greener” lubricants, room temperature ionic liquids, that represent a promising potential solution to many of the problems associated with both conventional lubricants and those based on natural oils. In this study, friction and wear tests were carried out using a pin-on-disk tribometer under ambient conditions to characterize the performance of the ionic liquids as lubricants. Specifically, ionic liquids consisting of salicylate, benzoate (common food additives) and saccharinate (an artificial sweetener) anions with conventional phosponium cations were evaluated as lubricants and compared to petroleum-based lubricants and natural oils in regards to structure and performance. The ionic liquids generally demonstrated better tribological performance than either the petroleum-based lubricants or natural oils. The mechanisms governing the chemical composition and improved tribological performance are discussed while highlighting possible industrial applications of this new class of lubricants.
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Kim, Yoon Jo, Sarah Kim, Yogendra K. Joshi, Andrei G. Fedorov, and Paul A. Kohl. "Waste-Heat Driven Miniature Absorption Refrigeration System Using Ionic-Liquid as a Working Fluid." In ASME 2011 5th International Conference on Energy Sustainability. ASMEDC, 2011. http://dx.doi.org/10.1115/es2011-54217.

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An ionic-liquid (IL) is a salt in a liquid state usually with an organic cation and inorganic anion. ILs provide an alternative to the normally toxic working fluids in absorption systems, such as the ammonia/water system. They also eliminate the problems of poor temperature match, crystallization and metal-compatibility problems of the water/LiBr system. In the present study, an IL is explored the working fluid of a miniature absorption refrigeration system so as to utilize waste-heat within the system for low-cost, high-power electronics cooling. To determine performance benchmarks for the refrigerant/IL (e.g. [bmim][PF6]) pairs, system-level simulations have been carried out. An NRTL model was built and used to predict the solubility of the mixture as well as the mixture properties such as enthalpy and entropy. The properties of the refrigerants were determined using REFPROP 6.0. Saturation temperatures at the evaporator and condenser were 25°C and 50°C, respectively. Chip power was fixed at 100 W with the operating temperature set at 85°C. R32 gave the highest operating efficiency with the maximum coefficient of performance (COP) of ca. 0.55 while R134a and R152a showed comparable performance with the maximum COP of ca. 0.4 at the desorber outlet temperature of 80°C. When waste-heat is available for the system operation, R134a and R152a COPs were comparable or better than that of R32.
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