Dissertations / Theses on the topic 'Animal physiology - biophysics'
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Ferreira, Matos Gomes Rute. "Respiratory mechanics in small animals : influence of size and age." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=38188.
Full textBeck, Jennifer 1968. "Effects of chest wall configuration and electrode positioning on human diaphragmatic EMG." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=22536.
Full textFive normal male subjects performed static contractions of the diaphragm at seven predetermined chest wall configurations. The EMGdi was measured with an array of eight steel rings mounted on a catheter, forming seven sequential pairs of electrodes, with an interelectrode distance of 10 mm. EMGdi signal quality was evaluated by computer algorithms. The pair of electrodes whose EMGdi signals (and power spectrums) were the least influenced by the MEdist filter was assumed to be closest to the diaphragm.
The results of the study indicated (1) EMGdi power spectrums and their associated CF values were strongly affected by the position of the diaphragm with respect to the multiple array esophageal electrode. CF decreased by approximately 1 Hz per mm displacement away from the diaphragm. (2) By controlling for the MEdist filter, there was no relationship found between changes in chest wall configuration and CF values. These data demonstrate that changes in chest wall configuration, and hence diaphragm length, do not influence the CF values of the EMGdi, if the distance between the electrodes and the diaphragm and signal quality are controlled for.
Krogh-Madsen, Trine. "Effects of single-channel noise on spontaneous beating and the phase-resetting response of cardiac oscillators." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85562.
Full textRecordings of transmembrane potential from small clusters of spontaneously beating 7-day-old embryonic chick ventricular cells were analyzed to characterize the voltage waveform and the regularity of beating. I constructed a deterministic Hodgkin-Huxley-type ionic model which reproduces spontaneous activity in our experimental recordings, as well as the experimental results of applying various ion channel blockers (D-600, almokalant, and Ba2+). The model consists of six currents: a calcium current (ICa), three potassium currents (IKs, I Kr, IK1), a background current ( Ib), and a seal-leak current (I seal).
The deterministic Hodgkin-Huxley-type model was then reformulated into a stochastic single-channel model. The single-channel model reproduces the irregularity of beating seen experimentally: e.g. the coefficient of variation of interbeat interval was 4.4% vs. 3.9% in the clusters. In the model, IKs is the current giving the major contributions to fluctuations in interbeat interval.
Phase resetting of the spontaneous activity of cardiac pacemaker cells by a brief stimulus pulse was simulated in Hodgkin-Huxley-type models and single-channel models of slow-upstroke (central) and fast-upstroke (peripheral) rabbit sinoatrial node cells. In the Hodgkin-Huxley-type models the phase-resetting response is continuous, but can be extremely delicate in the fast-upstroke model, in that a tiny difference in the stimulus timing can change the stimulus response from a delayed action potential to an advanced one. Therefore, the noise in the fast-upstroke single-channel model can cause a stimulus with fixed amplitude and fixed timing to have widely different effects: sometimes it will induce an action potential but in other cases it will delay an action potential, as seen previously in experiments on cardiac preparations.
Lewis, Timothy J. "Modeling conduction in the ventricles." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=60501.
Full textThe second model states that the highly ramified His-Purkinje system is reminiscent of a fractal branching structure, and that the ventricular myocardium is activated in a "fractal" (time-scale invariant) fashion, since it is activated via the His-Purkinje system. A 1/$f sp alpha$ power spectrum can sometimes be linked to fractal processes. The averaged power spectrum of single QRS complexes falls off as 1/$f sp alpha$ ($ alpha sim$ 4).
Liu, Qingde 1963. "Molecular and physical determinants of fibrinogen-dependent platelet aggregation and adhesion in flow." Thesis, McGill University, 1998. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35909.
Full textThough resting platelets are able to adhere to surface-bound Fg, this adhesion efficiency is much lower than that of the adhesion of the activated platelets. The adhesion efficiency of both resting and activated platelets to surface-adsorbed Fg decreases with increasing shear rate from 100 s -1 to 2,000 s-1. However, the decrease of the adhesion efficiency of the resting platelets is more marked than the decrease of the adhesion efficiency of the activated ones. Thus, the higher the shear rates, the larger the difference in the adhesion efficiencies between resting and activated platelets. However, due to the higher collision frequencies at higher shear rates, the adhesion of resting platelets was maintained at a similar level from shear rates of 300--2,000 s-1, while the adhesion of activated platelets kept increasing from 100 s -1 to 2,000 s-1. These data indicate that platelet activation is an efficient regulation pathway for platelet adhesion to surfaces.
Walker, Angela. "Electrochemical study of vesicular release in bovine chromaffin cells." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23431.
Full textFrequency histograms of the rise and decay times of the current spikes showed a paucity of very short duration events. Scatterograms of the rise and decay times consistently showed a positive relation, and the best fitted lines intercepted the ordinate (the axis of the decay time) at: 16.06 $ pm$ 6.45 msec (n = 11).
The effect of temperature changes upon the time course of release of content of individual vesicles in chromaffin cells was also examined. The amplitudes of the current spikes did not change significantly, whereas the rise times and the decay times diminished from (23.2 $ pm$ 11.6 to 11.9 $ pm$ 2.7 msec, and from 76.6 $ pm$ 25.4 to 47.3 $ pm$ 9.3 msec respectively) as the temperature was raised from 15$ sp circ$C to 35$ sp circ$C (n = 5). Nevertheless, the Q$ sb{10}$ values of the rise and decay times were surprisingly low.
The experimental findings suggest that in bovine chromaffin cells the duration of the release of content of single vesicles is much longer than in synapses. The results also suggest that this mechanism does not involve processes that are strongly temperature sensitive.
Young, Richard N. (Richard Norman). "The effect of muscle contractility on surface EMG /." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=60423.
Full textUsing surface electrodes we examined the EMG for 4 contraction levels at 5 ankle positions over 60$ sp circ$ of ankle rotation. The change in median frequency with muscle length identified a significant shift in the power spectrum to lower frequencies with increasing muscle length.
To further investigate our results we performed three other experiments: First, using X-rays to identify the relative change in distance between two intramuscular wire electrodes we found the change in TA muscle length for this study to be 15% over the 60$ sp circ$ of ankle rotation. Second, to test for synergist contamination we used fine wire electrodes in the Extensor Digitorum Longus and the Peroneus. We found no evidence to support significant contamination. Third, we examined the role of smaller electrodes with a smaller interelectrode distance on our findings. The EMG showed drastic changes with even a slight shift in electrode position most likely due to the large number of innervation zones.
Therefore, the results indicate a shift in the power spectrum with a change in muscle length. In addition, surface EMG results are heavily dependent on the innervation zones and on the electrode geometry, all of which are important considerations in developing the EMG as an accurate diagnostic tool.
Deng, Xiaoyan. "The effects of disturbed flows on mass transfer to and from an arterial wall /." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=70234.
Full textChen, Yuejin. "Characterization of the Vasoactivity of Tachykinins in Isolated Rat Kidney: Functional Studies and in Vitro Receptor Autoradiography." Digital Commons @ East Tennessee State University, 1994. https://dc.etsu.edu/etd/2892.
Full textHe, Dingsheng. "Connexins 40 and 43 form heteromeric gap junction channels in vascular smooth muscle cells." Diss., The University of Arizona, 1999. http://hdl.handle.net/10150/284991.
Full textGalloway, James Coleman. "Muscle torque-total torque relationships at the shoulder and elbow: Rules for initiating multijoint arm movements." Diss., The University of Arizona, 1998. http://hdl.handle.net/10150/282845.
Full textMaksym, Geoffrey N. "Modelling lung tissue theology." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=42087.
Full textSomasekharan, Suma. "NC-1059, a channel forming peptide, induces a reversible change in barrier function of epithelial monolayers." Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/553.
Full textMalreddy, Pradeep Reddy. "Potassium channels support anion secretion in porcine vas deferens epithelial cells." Thesis, Manhattan, Kan. : Kansas State University, 2009. http://hdl.handle.net/2097/1463.
Full textFouchard, Jonathan. "Relation entre forme, tension et adhésion au cours de l'étalement d'une cellule animale." Phd thesis, Université Paris-Diderot - Paris VII, 2012. http://tel.archives-ouvertes.fr/tel-00757194.
Full textYan, Dejun. "THE EFFECT OF CURCUMIN ON LEWIS LUNG CARCINOMA." Bowling Green State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1308588440.
Full textAnderson, Ross William. "Subthreshold Oscillations and Persistent Activity Modulate Spike Output in the Rodent Dentate Gyrus." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1415229722.
Full textMaillett, David H. "Engineering hemoglobins and myoglobins for efficient oxygen transport." Thesis, 2004. http://hdl.handle.net/1911/18666.
Full textWhitby, Frank G. "Structure of tropomyosin at 7A resolution." Thesis, 1995. http://hdl.handle.net/1911/16897.
Full textLindblad, Douglas S. "A model of the rate dependence of the atrial action potential in rabbit." Thesis, 1994. http://hdl.handle.net/1911/13859.
Full textShumaker, John Michael. "Conduction in a bullfrog atrial trabeculum: Active and passive properties, and modifications produced by acetylcholine." Thesis, 1992. http://hdl.handle.net/1911/16547.
Full textCates, Mary Susan. "Crystallographic and computational studies of the metal ion binding properties of parvalbumin." Thesis, 2000. http://hdl.handle.net/1911/19477.
Full textLu, Kun. "Human whole-body gas exchange and cerebral autoregulation studied using a cardiopulmonary model." Thesis, 2004. http://hdl.handle.net/1911/18665.
Full text"The elastic properties of the human mandible." Tulane University, 1989.
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"Sympathetic neurotransmission in primary hypertension." Tulane University, 1992.
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Nygren, Anders. "Mechanisms of repolarization and conduction in a mathematical model of electrophysiological responses in the human atrium." Thesis, 1998. http://hdl.handle.net/1911/19297.
Full textRamasubramanian, Anand. "Characterization of platelet glycoprotein Ib-IX-V: von Willebrand factor interaction under shear conditions." Thesis, 2004. http://hdl.handle.net/1911/18686.
Full textAzizi, Emanuel. "Biomechanics of salamander locomotion." 2005. https://scholarworks.umass.edu/dissertations/AAI3179854.
Full textLi, Li. "The influence of the inertial properties of the human body: Cycling at different pedaling speeds." 1999. https://scholarworks.umass.edu/dissertations/AAI9932325.
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