Academic literature on the topic 'Animal models'

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Journal articles on the topic "Animal models"

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Insel, Thomas R. "From Animal Models to Model Animals." Biological Psychiatry 62, no. 12 (December 2007): 1337–39. http://dx.doi.org/10.1016/j.biopsych.2007.10.001.

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HR, Siddique. "Animal Models in Cancer Chemoprevention." International Journal of Zoology and Animal Biology 2, no. 5 (2019): 1–5. http://dx.doi.org/10.23880/izab-16000171.

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Plaa, Gabriel L. "Animal Models." Drug Safety 5, Supplement 1 (1990): 40–45. http://dx.doi.org/10.2165/00002018-199000051-00007.

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Small, D. L., and A. M. Buchan. "Animal models." British Medical Bulletin 56, no. 2 (January 1, 2000): 307–17. http://dx.doi.org/10.1258/0007142001903238.

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Goetze, Jens P., and Andrew Krentz. "Animal models." Cardiovascular Endocrinology 3, no. 1 (March 2014): 1. http://dx.doi.org/10.1097/xce.0000000000000023.

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BARNES, DONALD J. "Animal models." Nature 329, no. 6141 (October 1987): 666. http://dx.doi.org/10.1038/329666c0.

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Lomberk, Gwen. "Animal models." Pancreatology 6, no. 5 (October 2006): 427–28. http://dx.doi.org/10.1159/000094559.

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Olivier, Berend. "Animal models." European Psychiatry 13, S4 (1998): 182s. http://dx.doi.org/10.1016/s0924-9338(99)80182-5.

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Moyer, Paula. "ANIMAL MODELS." Neurology Today 4, no. 1 (January 2004): 14. http://dx.doi.org/10.1097/00132985-200401000-00008.

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Saloman, Jami L., Kathryn M. Albers, Zobeida Cruz-Monserrate, Brian M. Davis, Mouad Edderkaoui, Guido Eibl, Ariel Y. Epouhe, et al. "Animal Models." Pancreas 48, no. 6 (July 2019): 759–79. http://dx.doi.org/10.1097/mpa.0000000000001335.

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Dissertations / Theses on the topic "Animal models"

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Yalçin, Biannaz. "QTL mapping in animal models." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410716.

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Mazzola, Carmen. "Neuropharmacology and Behaviural Animal Models." Thesis, Universita' degli Studi di Catania, 2011. http://hdl.handle.net/10761/93.

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Lo studio delle patologie umane richiede spesso l'ausilio di sperimentazioni animali. Generalmente i dati ottenuti in questi modelli permettono di ampliare le conoscenze sui meccanismi eziologici e sul trattamento delle patologie. Perche' un modello sperimentale sia considerato attendibile, deve avere specifici requisiti: face validity, construct validity and predictive validity. Rispettare tali criteri e' di enorme importanza per la ricerca in ambito fisiologico e farmacologico.
The study of human disease often involves performing physiological and pharmacological experiments in animal models. Generally, experimental results obtained in these models are extrapolated to the human situation, providing new insights into disease mechanisms and treatment options. To be able to reliably extrapolate results obtained in animal experiments, it is important to consider the validity of the animal model used, i.e., the extent to which the model mimics the disease. This validity is often characterized by 1) the resemblance in symptoms (face validity), 2) shared etiology and underlying pathophysiological mechanisms (construct validity), and 3) similarity of pharmacological responses (predictive validity). Hence, the analysis of face, construct, and predictive validity of animal models constitutes a very important aspect in the study of disease physiology and pharmacology.
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Klingström, Jonas. "Hantaviruses : animal models, immunology and pathogenesis /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-071-0/.

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Thomas, Kurt Florian Patrick. "Animal models of retroviral neurological diseases." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=39882.

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The neuropathogenicity of two retroviruses was investigated. The human immunodeficiency virus, in addition to its profound effect on the immune system, also causes degenerative changes in the brain, the spinal cord and peripheral nerves. In order to elucidate how it affects the nervous system, transgenic mice were generated that express the entire HIV genome in neurons in the anterior thalamus and in the anterior horn of the spinal cord, and examined clinically, neuropsychologically, electrophysiologically and histologically. Animals developed a neurological syndrome characterized by hypoactivity and weakness, and by axonal degeneration in peripheral nerves. These results provide evidence for a role of HIV in affecting both the central and peripheral nervous systems.
In a second project, pathological effects associated with a disease determining region contained in the gp70 envelope protein of the Cas-Br-E murine leukemia virus, were investigated. In infected mice, this virus causes hind limb paralysis and a spongiform myeloencephalopathy with gliosis and neuronal loss. Stably transfected fibroblasts that express gp70 were injected into the brains of mice, and the animals were examined for histopathological changes attributable to the effects of gp70. While gp70 protein was detected at the implantation site, this was not accompanied by any specific histological changes. These data suggest that the intracerebral expression of the neuropathogenic gp70 protein alone is not sufficient to cause disease, and lend indirect support to a model according to which gp70 causes disease by altering the cytokine profile of infected mononuclear cells in the central nervous system.
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Lydall, Emma Sian. "Palatability and animal models of schizophrenia." Thesis, Cardiff University, 2011. http://orca.cf.ac.uk/55071/.

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Schizophrenia is one of the most serious mental disorders of humankind. It affects about 1% of the population worldwide and has devastating consequences, including suicide in 10% of sufferers (e.g. Lewis & Lieberman, 2000). Schizophrenia also has serious social impact with sufferers accounting for more than one third of the homeless population in western society (Folsom & Jeste, 2002).
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Warren, Nicholas David. "Some stochastic models for animal territories." Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312289.

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Jusof, Felicita Fedelis. "Tryptophan-catabolising enzymes in animal models." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/13697.

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The first and rate-limiting step of the kynurenine pathway is the metabolism of tryptophan (Trp) to N-formylkynurenine, which is then rapidly converted to kynurenine. This initial step can be catalysed by three enzymes, tryptophan 2,3-dioxygenase (TDO), indoleamine 2, 3-dioxygenase-1 (IDO1) and the most recently discovered, IDO2. In adult mammals, TDO is expressed constitutively in the liver and is involved in the global regulation of tryptophan. IDO1 expression is mainly induced in various tissues during inflammatory conditions. IDO2, detected in the adult liver, may play a role in inflammation and autoimmune diseases. This report demonstrates the cellular localisation of IDO2 in adult mouse liver with Ido2-/- mice as the negative control, as well as the mRNA expression of Trp-catabolising enzymes in embryonic developmental series of zebrafish (tdo2a, tdo2b and ido) and mouse (Tdo2, Ido1 and Ido2). Both tdo2a and tdo2b were detected in zebrafish embryonic liver, whereas all three genes coding for Trp-catabolic enzymes were found in the intestine. In murine developmental tissues, Tdo2, Ido1 and Ido2 were all detectable in the yolk sac and placenta, with the expression of Tdo2 being the highest. Finally, this report also is the first to postulate a possible role for IDO2 in averting inflammation and metabolic dysregulation in the liver.
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Zemp, Franz Joseph, and University of Lethbridge Faculty of Arts and Science. "The bystander effect : animal and plant models." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2008, 2008. http://hdl.handle.net/10133/685.

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Bystander effects are traditionally known as a phenomenon whereby unexposed cells exhibit the molecular symptoms of stress exposure when adjacent or nearby cells are traversed by ionizing radiation. However, the realm of bystander effects can be expanded to include any systemic changes to cellular homeostasis in response to a number of biotic or abiotic stresses, in any molecular system. This thesis encompasses three independent experiments looking at bystander and bystander-like responses in both plant and animal models. In plants, an investigation into the regulation of small RNAs has given us some insights into the regulation of the plant hormone auxin in both stress-treated and systemic (bystander) leaves. Another plant model shows that a bystander-like plant-plant signal can be induced upon ionizing radiation to increase the genome instability of neighbouring unexposed (bystander) plants. In animals, it is shown that the microRNAome is largely affected in the bystander cells in a three-dimensional human tissue model. In silico and bioinfomatic analysis of this data provide us with clues as to the nature of bystander signalling in this human ‘in vivo’ model.
xiv, 141 p. : ill. ; 29 cm.
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Birrell, Mark Andrew. "Characterisation of animal models of airway eosinophilia." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408172.

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Nwosu, V. U. "Peroxisome enzymes in animal models of obesity." Thesis, University of Wolverhampton, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380662.

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Books on the topic "Animal models"

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National Institute on Alcohol Abuse and Alcoholism (U.S.), ed. Animal models. [Rockville, Md.]: Public Health Service, National Institutes of Health, 2000.

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Joost, Ruitenberg E., and Peters P. W. J, eds. Laboratory animals: Laboratory animal models for domestic animal production. Amsterdam: Elsevier Science Publishers, 1986.

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Davies, Jamie, ed. Replacing Animal Models. Chichester, UK: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781119940685.

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Technology Information Forecasting and Assessment Council (India), ed. Transgenic animal models. New Delhi: Technology Information, Forecasting, and Assessment Council, 2003.

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1948-, Gad Shayne C., and Chengelis Christopher P. 1949-, eds. Animal models in toxicology. New York: M. Dekker, 1992.

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King, Aileen J. F., ed. Animal Models of Diabetes. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0385-7.

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Risling, Mårten, and Johan Davidsson, eds. Animal Models of Neurotrauma. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9711-4.

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Sharpe-Timms, Kathy L., ed. Animal Models for Endometriosis. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-51856-1.

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Ma, Chao, and Jun-Ming Zhang, eds. Animal Models of Pain. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-60761-880-5.

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De Deyn, Peter Paul, and Debby Van Dam, eds. Animal Models of Dementia. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-60761-898-0.

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Book chapters on the topic "Animal models"

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Kreidberg, Jordan. "Animal Models." In Pediatric Nephrology, 397–417. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-76341-3_16.

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Fuchs, E., and H. Grötsch. "Animal Models." In Urinary Enzymes, 247–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-84313-6_16.

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Erf, Gisela F., and I. Caroline Le Poole. "Animal Models." In Vitiligo, 205–23. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-62960-5_22.

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Lee, Sungnack, Dongsik Bang, Eun-So Lee, and Seonghyang Sohn. "Animal Models." In Behçet’s Disease, 75–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56455-0_12.

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Nakai, Kozo, Kozo Yoneda, and Yasuo Kubota. "Animal Models." In Filaggrin, 65–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-54379-1_7.

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Flores, Sara, Farzam Gorouhi, and Howard I. Maibach. "Animal Models." In Textbook of Aging Skin, 781–85. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-89656-2_75.

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Walker, Ellen A. "Animal Models." In Chemo Fog, 138–46. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6306-2_18.

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Biessels, Geert Jan. "Animal Models." In Diabetes and the Brain, 387–408. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-850-8_16.

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Mårdh, Pers-Anders, Jorma Paavonen, and Mirja Puolakkainen. "Animal Models." In Chlamydia, 57–67. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0719-8_5.

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Erf, Gisela F. "Animal Models." In Vitiligo, 205–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-69361-1_25.

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Conference papers on the topic "Animal models"

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Kamaruddin, A. "Animal Models of Diseases." In 2nd International University of Malaya Research Imaging Symposium (UMRIS) 2005: Fundamentals of Molecular Imaging. Kuala Lumpur, Malaysia: Department of Biomedical Imaging, University of Malaya, 2005. http://dx.doi.org/10.2349/biij.1.1.e7-46.

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Khodanovich, M. Yu, and A. A. Kisel. "Animal models of cerebral ischemia." In NEW OPERATIONAL TECHNOLOGIES (NEWOT’2015): Proceedings of the 5th International Scientific Conference «New Operational Technologies». AIP Publishing LLC, 2015. http://dx.doi.org/10.1063/1.4936032.

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You, Wenjie. "Animal models of Parkinson's review." In 3RD INTERNATIONAL CONFERENCE ON FRONTIERS OF BIOLOGICAL SCIENCES AND ENGINEERING (FBSE 2020). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0050911.

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Bergant, Marko, and Helena Gabrijelčič Tomc. "Display of interactive 3D models in augmented reality on mobile devices." In 11th International Symposium on Graphic Engineering and Design. University of Novi Sad, Faculty of technical sciences, Department of graphic engineering and design, 2022. http://dx.doi.org/10.24867/grid-2022-p19.

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This paper study is related to two research areas, namely 3D computer graphics and augmented reality with a combination of their display on mobile devices. It presents the creation of three different interactive 3D models based on a realistically drawn image of domestic animals and can be displayed on mobile devices using augmented reality. The textured animals' models are displayed in the application Augmented animals (slo. Obogatene živali) with a simple user interface. The usability of the application is demonstrated by the detection of the image target, i.e., a printed interactive card, which proves the interaction between the mobile device and the augmented paper. When the mobile device camera recognizes the target, it displays the selected animal on the screen. The result is the enhancement of the real environment with animated 3D characters. By displaying a 3D character on the screen and interacting with the user interface, the presentation of each animal in three different animated movements is enabled. The first empirical part of this work was done with the help of the Blender program, in which we created all three animal 3D characters. First, we had to model all the animals from the initial templates into a recognizable 3D mesh, which we then mapped the textures on. This was followed by the construction of a system of bones and animation controls, based on which we could create the animal animations. After this step, we transferred the project to the Unity program. Then it followed the construction of an application that allows the representation of characters in augmented reality. The results of the entire work are appropriately made animal characters in the form of animated 3D models that can be displayed in augmented reality mode on mobile devices using interactive cards. The selected testing parameters showed that there are certain differences in rendering between the two tested mobile devices depending on the selected subdivision level of the 3D character. However, for recognition based on lighting conditions, distance and slope between the image target and the mobile device, the best user experience is obtained when the image target is captured from a distance of 15-20 cm and from a bird's eye view under good lighting conditions.
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Fruhner, Maik, and Heiko Tapken. "Towards Multi-Species Animal Re-Identification." In Computer Science Research Notes. University of West Bohemia, Czech Republic, 2024. http://dx.doi.org/10.24132/csrn.3401.15.

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Animal Re-Identification (ReID) is a computer vision task that aims to retrieve a query individual from a gallery of known identities across different camera perspectives. It is closely related to the well-researched topic of Person ReID, but offers a much broader spectrum of features due to the large number of animal species. This raises research questions regarding domain generalization from persons to animals and across multiple animal species. In this paper, we present research on the adaptation of popular deep learning-based person ReID algorithms to the animal domain as well as their ability to generalize across species. We introduce two novel datasets for animal ReID. The first one contains images of 376 different wild common toads. The second dataset consists of various species of zoo animals. Subsequently, we optimize various ReID models on these datasets, as well as on 20 datasets published by others, with the objective of evaluating the performance of the models in a non-person domain. Our findings indicate that the domain generalization capabilities of OSNet AIN extend beyond the person ReID task, despite its comparatively small size. This enables us to investigate real-time animal ReID on live video data.
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Liu, Emma. "EXPLORING ANIMAL MOVEMENT BEHAVIOR WITH SWITCHING STATE SPACE MODELS." In BioTecnica 2024 –International Conference on Advances in Biological Sciences, 19-20 January, Tokyo. Global Research & Development Services, 2024. http://dx.doi.org/10.20319/icrlsh.2024.0415.

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Understanding animal movement is pivotal in addressing population dynamics. Bayesian statistical techniques have been concentrated in literature to study intricate animal movement, by adapting their analytically manageable likelihoods. With the utilization of Hidden Markov Models (HMMs), the study examines animal tracking data of one elk and highlights step lengths and turning angles across two states. Data is obtained from the work of Morales et al. (2004), titled "Extracting more out of relocation data: building movement models as mixtures of random walks." Collected using tracking systems, the data indicates elk position (longitude and latitude), and the animal’s proximity to water sources along its movement paths. To effectively analyze step length and turning angles on HMMs, Gamma and Von Mises distributions and employed respectively. Results indicate a difference in step length between states 1 and 2, with longer steps observed in state 2 than in state 1. In turning angles, state 1 showcases a uniform distribution, signifying undirected movement in comparison to State 2 which showcases directed movement. The study concludes that movement in state 1 is indicative of foraging, while state 2 signifies traveling between habitat patches and wandering movements, and that the elk grazes closer to water and forages away from water.
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Yi-Xue Li. "Whole genome sequencing of disease animal models." In 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2016. http://dx.doi.org/10.1109/bibm.2016.7822475.

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Ponthan, Frida, Matthew Brown, Emma Playle, and Catherine Booth. "Abstract 1061: Animal models of prostate cancer." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-1061.

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Ponthan, Frida, Matthew Brown, Emma Playle, and Catherine Booth. "Abstract 1061: Animal models of prostate cancer." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1061.

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Yu, X. "SP0002 Novel animal models in systemic sclerosis." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.7128.

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Reports on the topic "Animal models"

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Borjigin, Jimo. Animal Models of Jet Lag. Fort Belvoir, VA: Defense Technical Information Center, January 2012. http://dx.doi.org/10.21236/ada567479.

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Hanson, William L. Evaluation of Antileishmanial Drugs in Animal Models. Fort Belvoir, VA: Defense Technical Information Center, March 2000. http://dx.doi.org/10.21236/ada382788.

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Medina, Richard L., and Richard A. Albanese. Animal-to-Human Extrapolation Using Compartmental Models. Fort Belvoir, VA: Defense Technical Information Center, January 1991. http://dx.doi.org/10.21236/ada234082.

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Villegas Aguilar, Julio Cesar, Marco Felipe Salas Orozco, Maria de los Angeles Moyaho Bernal, Eric Reyes Cervantes, Julia Flores-Tochihuitl, Alberto Vinicio Jerezano Domínguez, and Miguel Angel Casillas Santana. Mechanical vibrations and increased alveolar bone density in animal models as an alternative to improve bone quality during orthodontic treatment: A systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2022. http://dx.doi.org/10.37766/inplasy2022.8.0103.

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Review question / Objective: The aim of this systematic review is to determine whether mechanical vibration increases alveolar bone density in animals models and their possible application during orthodontic treatment. In this sense, the focused question is: Is the increase in alveolar bone density by mechanical vibrations in animal models an alternative to improve bone quality during orthodontic treatment? Eligibility criteria: All published animal studies will be included. Animal studies where high or low frequency vibrations were be applied, Articles where density or osteogenesis were be measured and compared to a control group. All publications will be considered except for those where the full-text article will not available, or the authors’ affiliation or the place of publication will not be specified. Only articles published in English.
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Wang, Zhou. Enhancement of Intermittent Androgen Ablation Therapy by Finasteride Administration in Animal Models. Fort Belvoir, VA: Defense Technical Information Center, February 2005. http://dx.doi.org/10.21236/ada439240.

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Wang, Zhou. Enhancement of Intermittent Androgen Ablation Therapy by Finasteride Administration in Animal Models. Fort Belvoir, VA: Defense Technical Information Center, February 2006. http://dx.doi.org/10.21236/ada448498.

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Wang, Zhou. Enhancement of Intermittent Androgen Ablation Therapy by Finasteride Administration in Animal Models. Fort Belvoir, VA: Defense Technical Information Center, February 2003. http://dx.doi.org/10.21236/ada414795.

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Gregerson, Karen A. Human-Compatible Animal Models for Preclinical Research on Hormones in Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada574629.

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Wang, Zhou. Enhancement of Intermittent Androgen Ablation Therapy by Finasteride Administration in Animal Models. Fort Belvoir, VA: Defense Technical Information Center, February 2004. http://dx.doi.org/10.21236/ada423671.

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Li, Guangyao, Yuling Shi, Chuanghui Yang, Jinghu Li, Xueqin Hong, and Min Li. A Bayesian network meta-analysis of acupuncture to treat vascular dementia in animal models. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2021. http://dx.doi.org/10.37766/inplasy2021.11.0036.

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