Academic literature on the topic 'Angiostrongylus cantonensis'

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Journal articles on the topic "Angiostrongylus cantonensis"

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Ash, L. R. "Angiostrongylus cantonensis." Journal of Neurology, Neurosurgery & Psychiatry 55, no. 9 (September 1, 1992): 861. http://dx.doi.org/10.1136/jnnp.55.9.861.

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Pien, Francis D., and Brian C. Pien. "Angiostrongylus cantonensis eosinophilic meningitis." International Journal of Infectious Diseases 3, no. 3 (1999): 161–63. http://dx.doi.org/10.1016/s1201-9712(99)90039-5.

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Ansdell, Vernon, and Yupaporn Wattanagoon. "Angiostrongylus cantonensis in travelers." Current Opinion in Infectious Diseases 31, no. 5 (October 2018): 399–408. http://dx.doi.org/10.1097/qco.0000000000000481.

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Valentyne, Hayley, David M. Spratt, Mahdis Aghazadeh, Malcolm K. Jones, and Jan Šlapeta. "The mitochondrial genome of Angiostrongylus mackerrasae is distinct from A. cantonensis and A. malaysiensis." Parasitology 147, no. 6 (February 13, 2020): 681–88. http://dx.doi.org/10.1017/s0031182020000232.

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AbstractThe native rat lungworm (Angiostrongylus mackerrasae) and the invasive rat lungworm (Angiostrongylus cantonensis) occur in eastern Australia. The species identity of A. mackerrasae remained unquestioned until relatively recently, when compilation of mtDNA data indicated that A. mackerrasae sensu Aghazadeh et al. (2015b) clusters within A. cantonensis based on their mitochondrial genomes (mtDNA). To re-evaluate the species identity of A. mackerrasae, we sought material that would be morphologically conspecific with A. mackerrasae. We combined morphological and molecular approaches to confirm or refute the specific status of A. mackerrasae. Nematodes conspecific with A. mackerrasae from Rattus fuscipes and Rattus rattus were collected in Queensland, Australia. Morphologically identified A. mackerrasae voucher specimens were characterized using amplification of cox1 followed by the generation of reference complete mtDNA. The morphologically distinct A. cantonensis, A. mackerrasae and A. malaysiensis are genetically distinguishable forming a monophyletic mtDNA lineage. We conclude that A. mackerrasae sensu Aghazadeh et al. (2015b) is a misidentified specimen of A. cantonensis. The availability of the mtDNA genome of A. mackerrasae enables its unequivocal genetic identification and differentiation from other Angiostrongylus species.
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Maki, Jun, and Toshio Yanagisawa. "Demonstration of carboxyl and thiol protease activities in adult Schistosoma mansoni, Dirofilaria immitis, Angiostrongylus cantonensis and Ascaris suum." Journal of Helminthology 60, no. 1 (March 1986): 31–37. http://dx.doi.org/10.1017/s0022149x00008191.

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AbstractEvidence has been presented showing two kinds of acidic protease activities in adult Schistosoma mansoni, Dirofilaria immitis, Angiostrongylus cantonensis and Ascaris suum. A haemoglobinolytic activity without adding any SH-containing compounds was maximal at pH 3.5, 2.5, 30 and 3.5 in S. mansoni, D. immitis, Angiostrongylus cantonensis and Ascaris suum respectively. The inhibitor studies demonstrated that this activity is ascribable to carboxyl protease(s). In the presence of dithiothreitol, activity on Azocoll (azo-dye coupled hide powder) was maximal at pH 4.6, 4.6, 3.5 and 5.6 in S. mansoni, D. immitis, Angiostrongylus cantonensis and Ascaris suum respectively. The effects of inhibitors demonstrated that this activity belongs to the thiol protease class. The intraspecific distribution of the protease activities was studied in some of the nematodes from which the organs could be anatomically separated. The distribution patterns of the haemoglobinolytic and azocollytic activities were quite different in An. cantonensis and much the same in As. suum. Based on the present results, acidic haemoglobinolytic activities reported in adult S. mansoni by other authors are thought to be due to carboxyl and thiol protease(s) respectively.
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Eamsobhana, P., P. E. Lim, and H. S. Yong. "Phylogenetics and systematics of Angiostrongylus lungworms and related taxa (Nematoda: Metastrongyloidea) inferred from the nuclear small subunit (SSU) ribosomal DNA sequences." Journal of Helminthology 89, no. 3 (March 13, 2014): 317–25. http://dx.doi.org/10.1017/s0022149x14000108.

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AbstractThe Angiostrongylus lungworms are of public health and veterinary concern in many countries. At the family level, the Angiostrongylus lungworms have been included in the family Angiostrongylidae or the family Metastrongylidae. The present study was undertaken to determine the usefulness and suitability of the nuclear 18S (small subunit, SSU) rDNA sequences for differentiating various taxa of the genus Angiostrongylus, as well as to determine the systematics and phylogenetic relationship of Angiostrongylus species and other metastrongyloid taxa. This study revealed six 18S (SSU) haplotypes in A. cantonensis, indicating considerable genetic diversity. The uncorrected pairwise ‘p’ distances among A. cantonensis ranged from 0 to 0.86%. The 18S (SSU) rDNA sequences unequivocally distinguished the five Angiostrongylus species, confirmed the close relationship of A. cantonensis and A. malaysiensis and that of A. costaricensis and A. dujardini, and were consistent with the family status of Angiostrongylidae and Metastrongylidae. In all cases, the congeneric metastrongyloid species clustered together. There was no supporting evidence to include the genus Skrjabingylus as a member of Metastrongylidae. The genera Aelurostrongylus and Didelphostrongylus were not recovered with Angiostrongylus, indicating polyphyly of the Angiostrongylidae. Of the currently recognized families of Metastrongyloidea, only Crenosomatidae appeared to be monophyletic. In view of the unsettled questions regarding the phylogenetic relationships of various taxa of the metastrongyloid worms, further analyses using more markers and more taxa are warranted.
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Espírito-Santo, Maria Cristina Carvalho do, Pedro Luiz Silva Pinto, Dan Jesse Gonçalves da Mota, and Ronaldo César Borges Gryschek. "THE FIRST CASE OF Angiostrongylus cantonensis EOSINOPHILIC MENINGITIS DIAGNOSED IN THE CITY OF SÃO PAULO, BRAZIL." Revista do Instituto de Medicina Tropical de São Paulo 55, no. 2 (April 2013): 129–32. http://dx.doi.org/10.1590/s0036-46652013000200012.

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Introduction:Angiostrongylus cantonensis is a natural parasite found in lung arteries of rats, which in humans may cause eosinophilic meningitis. Objective: To report the first case of eosinophilic meningitis caused by Angiostrongylus cantonensis in the city of São Paulo, Brazil. Case report: A male patient, 11 years old, living in the southern area of São Paulo, was admitted to the Pediatric Emergency Department with ongoing headaches for three days, but no fever or any other complaint. The presence of snails and rodents was reported in the peridomicile. The child was awake, lucid, oriented; muscular strength preserved, isochoric, photo reagent pupils and terminal nuchal rigidity - Glasgow Coma Scale (GCS) = 15. The laboratory tests showed a mild leukocytosis with 1736 eosinophils/mm3 and the CSF analysis disclosed 160 leukocytes/mm3 with 36% of eosinophils. The bacterial culture was negative. Computed Cerebral Tomography showed no alterations. The RT-PCR assay for detecting Angiostrongylus cantonensis larvae and DNA was negative. ELISA antibodies for IgG anti-A. cantonensis was negative in serum and undetermined in CSF and samples collected five days after the onset of symptoms. Seroconversion was observed in the sample collected 135 days later. Conclusion: the epidemiological and clinical data, the CSF alterations with eosinophilia and the seroconversion strongly suggest Angiostrongylus cantonensis eosinophilic meningitis.
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AGHAZADEH, MAHDIS, MARINA C. HARVIE, HELEN C. OWEN, CAROLINA VERÍSSIMO, KIERAN V. ALAND, SIMON A. REID, REBECCA J. TRAUB, DONALD P. McMANUS, JAMES S. McCARTHY, and MALCOLM K. JONES. "Comparative pathogenesis of eosinophilic meningitis caused by Angiostrongylus mackerrasae and Angiostrongylus cantonensis in murine and guinea pig models of human infection." Parasitology 143, no. 10 (June 9, 2016): 1243–51. http://dx.doi.org/10.1017/s003118201600069x.

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SUMMARYThis study investigated comparatively the pathogenicity of experimental infection of mice and guinea pigs, with Angiostrongylus mackerrasae and the closely related species A. cantonensis. Time course analyses showed that A. mackerrasae causes eosinophilic meningitis in these hosts, which suggests that the species has the potential to cause meningitis in humans and domestic animals. Both A. mackerrasae and the genetically similar A. cantonensis caused eosinophilic meningitis in mice at two time points of 14 and 21 days post infection (dpi). The brain lesions in mice infected with A. mackerrasae were more granulomatous in nature and the parasites were more likely to appear degenerate compared with lesions caused by A. cantonensis. This may indicate that the mouse immune system eliminates A. mackerrasae infection more effectively. The immunologic responses of mice infected with the two Angiostrongylus species was compared by assessing ex vivo stimulated spleen derived T cells and cytokines including interferon-gamma, interleukin 4 and interleukin 17 on 14 and 21 dpi. The results were similar for mice infected with A. cantonensis and A. mackerrasae. Serum from the infected animals with either A. cantonensis or A. mackerrasae recognized total soluble antigen of A. cantonensis female worms on Western blot.
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Ramos-Robledo, Alejandro, Christian Meijides-Mejías, Rolando Zamora-Fung, and Alberto Juan Dorta-Contreras. "Meningoencefalitis eosinofílica por Angiostrongylus cantonensis." Archivos de Neurociencias 25, no. 2 (August 3, 2020): 45–56. http://dx.doi.org/10.31157/an.v25i2.237.

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Angiostrongylus cantonensis (A. cantonensis) es un helminto que constituye la principal causa de meningoencefalitis eosinofílica en el mundo y endémica en muchas partes del mundo. El objetivo de este trabajo es revisar la literatura publicada sobre el tema sobre el diagnóstico y tratamiento de la enfermedad que ocasiona, la fisiopatología de la enfermedad, casos interesantes y las particularidades de esta donde no existan hábitos de ingerir caracoles crudos y no existan otras etiologías. Se revisaron 37 artículos sobre la enfermedad en revistas nacionales e internacionales de acceso abierto que abarca la base de datos Scopus en el período de 1957 a octubre de 2019. Se confirma que la liberación de sustancias tóxicas, por lisis masiva de las larvas del parásito, produce el proceso inflamatorio en el sistema nervioso central y de esta manera se instaura finalmente la meningoencefalitis eosinofílica. Las manifestaciones clínicas más comunes de la enfermedad incluyen cefalea intensa, rigidez de nuca, náuseas, vómitos y parestesias. La fiebre se presenta en aproximadamente en la tercera parte de los enfermos. Los síntomas y los signos son a menudo leves o moderados, pero pueden llegar el coma. El diagnóstico está basado en los factores epidemiológicos, cuadro clínico presentado, así como los hallazgos positivos de los métodos diagnósticos inmunológicos y por PCR y los reibergramas como auxiliares. El tratamiento presenta alternativas al tratamiento sintomático con la talidomida y albendazol y la terapéutica combinada Interleucina-12 (IL-12) /Albendazol ensayada hasta ahora en ratas.
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Ramos-Robledo, Alejandro, Christian Meijides-Mejías, Rolando Zamora-Fung, and Alberto Juan Dorta-Contreras. "Meningoencefalitis eosinofílica por Angiostrongylus cantonensis." Archivos de Neurociencias 25, no. 2 (August 3, 2020): 45–56. http://dx.doi.org/10.31157/archneurosciencesmex.v25i2.237.

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Angiostrongylus cantonensis (A. cantonensis) es un helminto que constituye la principal causa de meningoencefalitis eosinofílica en el mundo y endémica en muchas partes del mundo. El objetivo de este trabajo es revisar la literatura publicada sobre el tema sobre el diagnóstico y tratamiento de la enfermedad que ocasiona, la fisiopatología de la enfermedad, casos interesantes y las particularidades de esta donde no existan hábitos de ingerir caracoles crudos y no existan otras etiologías. Se revisaron 37 artículos sobre la enfermedad en revistas nacionales e internacionales de acceso abierto que abarca la base de datos Scopus en el período de 1957 a octubre de 2019. Se confirma que la liberación de sustancias tóxicas, por lisis masiva de las larvas del parásito, produce el proceso inflamatorio en el sistema nervioso central y de esta manera se instaura finalmente la meningoencefalitis eosinofílica. Las manifestaciones clínicas más comunes de la enfermedad incluyen cefalea intensa, rigidez de nuca, náuseas, vómitos y parestesias. La fiebre se presenta en aproximadamente en la tercera parte de los enfermos. Los síntomas y los signos son a menudo leves o moderados, pero pueden llegar el coma. El diagnóstico está basado en los factores epidemiológicos, cuadro clínico presentado, así como los hallazgos positivos de los métodos diagnósticos inmunológicos y por PCR y los reibergramas como auxiliares. El tratamiento presenta alternativas al tratamiento sintomático con la talidomida y albendazol y la terapéutica combinada Interleucina-12 (IL-12) /Albendazol ensayada hasta ahora en ratas.
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Dissertations / Theses on the topic "Angiostrongylus cantonensis"

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Ramos, Raquel Rocha. "Estudo sobre moléculas com atividade hemoglobinolítica em Angiostrongylus costaricensis e Angiostrongylus cantonensis." Pontifícia Universidade Católica do Rio Grande do Sul, 2009. http://hdl.handle.net/10923/1300.

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The two main species in the genus Angiostrongylus that cause human disease are A. cantonensis and A. costaricensis. These parasites have different tissue tropism, A. cantonesis is neurotropic and causes eosinophilic meningoencephalitis, A. costaricensis is located in the mesentery causing abdominal angiostrongyliasis. Immunological tests currently used for angiostrongyliasis diagnosis are limited by low especificity. Otherwise, specialized functional proteins, such as enzymes, may lead to more specific reactivity. The aim of the present work is to identify hemoglobinotytic activity in A. cantonensis. Digestive organs from the female worms were homogenized in lyses buffer. The protein extract (AcPE) was incubated whit bovine hemoglobin (BHh) at different pH range. Zymography assay was carried out by copolimerized SDS-PAGE with either 0. 4% BHb or 0. 1% gelatin. Hemoglobin degradation was well demonstrated at an extensive pH range, from 3. 0 to 7. 0. No degradation bands were detected by zymography either with gelatin or hemoglobin as substrate. These limited data from zymography and those from pH titration may suggest that AcPE contains not a single component but a low abundance enzyme complex. The identification, characterization and clonning of molecules with hemoglobinolytic activity stays as a prioritary aim.
Angiostrongylus costaricensis e A. cantonensis são as principais espécies patogênicas para o homem no gênero Angiostrongylus. Esses parasitos tem tropismo tecidual diferentes, A. cantonensis é um parasito neurotrópico que causa a angiostrongilíase meningoencefálica e A. costaricensis localiza-se no mesentério sendo o agente etiológico da angiostrongilíase abdominal. Os testes imunológicos utilizados ultimamente para o diagnóstico das Angiostrongilíases são limitados pela baixa especificidade. Entretanto, proteínas funcionais especializadas, tais como enzimas, podem ser fontes de reatividade imunológica específica. O objetivo do presente trabalho é identificar atividade hemoglobinolítica nesses parasitos. Tubos digestivos de fêmeas foram homogeneizadas em tampão de lise. As proteínas do extrato (ExAca) foram incubadas com hemoglobina bovina (HbB) em diferentes pHs. Zimografia foi realizado em géis copolimerizados com 0,4% gelatina ou 0,1% BHb. Degradação da hemoglobina foi bem demonstrada em uma ampla faixa de pH, de 3,0 para 7,0. Não foram detectadas bandas de degradação na zimografia com gelatina ou hemoglobina como substrato. Os dados limitados da zimografia e os resultados de atividade hemoglobinolítica, com ou sem a titulação de pH, pode sugerir um complexo de proteases em pequena quantidade. Exploração de diversas estratégias de concentração do extrato protéico, sem perda da atividade da enzima, constitue a perspectiva desse trabalho, visando à identificação, caracterização e produção em larga escala de moléculas com atividade hemoglobinolítica.
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Ben, Renata. "Ausência do endosimbionte Wolbachia SP. em dois metastrongilídeos: Angiostrongylus costaricensis e Angiostrongylus cantonensis." Pontifícia Universidade Católica do Rio Grande do Sul, 2007. http://hdl.handle.net/10923/5343.

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Abdominal angiostrongyliasis is caused by Angiostrongylus costaricensis, an intra-arterial nematode, that lives in the ileocecal region in wild rodents. This parasite has been detected from southern United States to northern Argentina. Man is an accidental host and is infected ingesting third stage larvae (L3) that are eliminated with mucous secretions by the intermediate host (veronicelid slugs). Another species, that also may infect man is Angiostrongylus cantonensis, a rat pulmonary worm, responsabile for eosinophilic meningitis, in Asia and Pacific islands. Parasites of parasites are currently being studied not only to open new therapeutics possibilities, but also in order to improve diagnostic techniques. The interest for Wolbachia, a gram-negative endosimbiont bacterium, increased when the mutualistic character of its association with filarias was described. These considerations led to new ideas for treatment of these parasitosis through the use of antibacterial drugs. The main objective of this work is to verify the Wolbachia sp presence in A. costaricensis and A. cantonensis, and study its contribution for the humoral immune response of the vertebrate host. The first step was to look for evidences in favor of the presence of Wolbachia sp. Nucleic acids, through the PCR technique. In some experiments amplification products were obtained, what could be an indication of the presence of the bacterium, but these data must be confirmed by electronic microscopy and immunohistology. Because of the difficulties to get Wolbachia sp. antigen, alternatively serum samples from individuals with abdominal angiostrongyliasis were tested against Escherichia coli antigen, because it is a common bacterium species in vertebrates’ microbiota that could eventually colonize the worm. Through a western-blot analysis it was clearly demonstrated a reactivity not exclusively associated to A. costaricensis’ infected individuals. Moreover, fragments of worms were introduced in bacterial culture medium in order to study the microbiota of the Angiostrongylus adult worm. The fact of being found only one species of a grampositive bacillum in this experiment seems to confirm the hypothesis that in intravascular environment, with a low tolerance for bacteria, the worm’s microbiota is reduced in number and diversity. From the experiments we were not able to identify the presence of Wolbachia sp neither in A. costaricensis nor in A. cantonensis. It remains open to further investigations the contribution of other bacteria or simbionts of helminthes, for antigenic recognition by the vertebrate host, with potential implications for diagnosis, pathogenesis and treatment
A angiostrongilíase abdominal é causada pelo Angiostrongylus costaricensis, um nematódeo intra-arterial, que vive na região íleo-cecal de roedores silvestres. Esta parasitose tem sido registrada desde o sul dos Estados Unidos até o norte da Argentina. O homem é hospedeiro acidental e se infecta ingerindo as larvas de terceiro estágio (L3) presentes no muco do hospedeiro intermediário (veronicelídeos). Outra espécie, que também é parasita do homem, é Angiostrongylus cantonensis, um verme pulmonar de ratos, causador da meningite eosinofílica, que ocorre na Ásia e ilhas do Pacífico. Parasitas de parasitas são atualmente alvo de estudos não somente para abrir novas possibilidades terapêuticas, bem como para aprimorar técnicas diagnósticas. O interesse pela Wolbachia sp, uma bactéria gram-negativa endosimbionte, aumentou no momento em que descobriram sua característica mutualística em relação à filária. Estas considerações levaram a novas idéias para o tratamento destas parasitoses através da utilização de drogas antibacterianas. O objetivo principal deste trabalho é verificar a presença de Wolbachia em A. costaricensis e em A. cantonensis, e estudar a sua contribuição para a resposta imune humoral do hospedeiro vertebrado. O primeiro passo foi buscar evidências da presença de ácidos nucléicos de Wolbachia, através da técnica de PCR. Em alguns experimentos foram obtidos produtos de amplificação, o que poderia ser um indício da presença da bactéria, mas esses dados devem ser confirmados por microscopia eletrônica e por imunohistologia. Diante das dificuldades para se obter antígeno de Wolbachia sp alternativamente amostras de soro de indivíduos com angiostrongilíase foram testados contra antígenos de Escherichia coli por ser uma bactéria comum na microbiota de vertebrados e que eventualmente poderia colonizar o verme. Através da análise por imunoeletrotransferência ficou claramente demonstrada uma reatividade não relacionada exclusivamente aos indivíduos infectados por A. costaricensis. Além disso, fragmentos de vermes foram semeados em meio de cultura a fim de estudar a microbiota do verme adulto de Angiostrongylus. O fato de só ser encontrada um bacilo gram positivo nesse experimento parece confirmar a hipótese de que, por ser o ambiente intravascular pouco tolerante à presença de bactérias, a microbiota do verme deve ser pouco numerosa e diversa. Permanece aberta para futuras investigações a contribuição de outras bactérias ou outros simbiontes em helmintos, para reconhecimento antigênico pelo hospedeiro vertebrado, com possíveis implicações para diagnóstico, patogenia e tratamento.
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Paula, Alessandra Teixeira de. "Controle biológico de Angiostrongylus cantonensis utilizando fungos nematófagos." Universidade Federal de Viçosa, 2014. http://locus.ufv.br/handle/123456789/5187.

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The parasitosis, in a medical and social standpoint, presents important public health problems. In Brazil, an average of a third of population lives in areas with risk of transmission and occurrence of parasitic diseases. The lack of basic sanitation, as well as environmental factors particular of tropical climates, inequality of the socioeconomic conditions of the individuals and the lack of information are factors that favor its occurrence. The colonization process, establishment of new routes of trade and human migration, contributed to the introduction of pathogens transported by their hosts to other regions. This way, various species found out of their origin area. The parasite Angiostrongylus cantonensis and the exotic snail Achatina fulica are two examples of organisms that were introduced in Brazil. A.fulica is one of the intermediate hosts of the parasite A. cantonensis, responsible for cause in humans, disease known as eosinophilic meningoencephalitis, may lead parasitized individuals to death. In various regions of the country, was confirmed the presence of this parasite naturally occurring, as well as cases of infected humans. This way, measures of alternative control, are important to avoid its dispersion. In this context was evaluated the predatory capability of eight fungal isolates belong to the species Duddingtonia flagrans (isolated: AC001, CG768 and CG722), Monacrosporium thaumasium (isolated: NF34), M. sinense (isolated: SF53) and Arthobotrys robusta (isolated: I31), A. cladodes (isolated: CG719) and A. conoídes (isolated: I40) on first larvae stage (L1) of A. cantonensis in laboratory conditions. Were formed nine groups: eight groups treated with the different isolated and one control group (without fungi). The groups treated contained 1000 conidia of isolated fungal and 1000 L1 of A. cantonensis in Petri dish containing Agar- water 2% (AA2%). The control group contained only 1000 L1 of A. cantonensis in AA2%. Evidence of predatory activity of all fungal isolates tested could be observed at the end of seven days of the experiment through the recovery of ixnon-predated L1, where were observed the following percentage of reduction of L1 with the respective isolates: AC001 (82,8%); CG768 (71,0%); CG722 (72,8%); NF34 (86,7%), SF53 (89,7%); I40 (48,3%), CG719 (84,7%) and I31 (80,4%). No difference was observed (p>0,01) between the action of the isolated used in the end of seven days, however, was observed difference (p<0,01) compared with the control group. The results observed demonstrated that the fungi belonged to the genus Duddingtonia (AC001, CG768 and CG722), Monacrosporium (NF34 and SF53) and Arthrobotrys (I31 and CG719), could be used in biological control, once that these were capable of reduce the population of larvae (L1) of A. cantonensis in vitro.
As parasitoses, do ponto de vista médico e social, representam importantes problemas de saúde pública. No Brasil, em média um terço da população vive em áreas com risco de transmissão e ocorrência de doenças parasitárias. A falta de saneamento básico, bem como fatores ambientais próprios de clima tropical, desigualdade das condições socioeconômicas dos indivíduos e a falta de informação favorecem sua ocorrência. Os processos de colonização, estabelecimento de novas rotas de comércio e migração humana, contribuíram para a introdução de patógenos transportados por seus hospedeiros para outras regiões. Dessa forma, várias espécies se encontram fora de sua área de origem. O parasito Angiostrongylus cantonensis e o caramujo exótico Achatina fulica, são dois exemplos de organismos que foram introduzidos no Brasil. A. fulica é um dos hospedeiros intermediários do parasito A. cantonensis, responsável por causar em humanos, doença conhecida como meningoencefalite eosinofilica, podendo levar indivíduos parasitados a óbito. Em várias regiões do país, foi confirmada a presença deste parasito ocorrendo naturalmente, bem como casos de humanos infectados. Dessa forma, medidas de controle alternativo, são importantes para evitar sua dispersão. Nesse contexto foi avaliada a capacidade predatória de oito isolados fúngicos pertencentes ás espécies Duddingtonia flagrans (isolados: AC001, CG768 e CG722), Monacrosporium thaumasium (isolado: NF34), M. sinense (isolado: SF53) e Arthobotrys robusta (isolado: I31), A. cladodes (isolado: CG719) e A. conoídes (isolado: I40) sobre larvas de primeiro estádio (L1) de A. cantonensis em condições laboratoriais. Foram formados nove grupos: oito grupos tratados com os diferentes isolados, e um grupo controle (sem fungos). Os grupos tratados continham 1000 conídios dos isolados fúngicos e 1000 L1 de A. cantonensis em placa de Petri contendo o meio Agar-água 2% (AA2%). O viigrupo controle continha apenas 1000 L1 de A. cantonensis em AA2%. Evidências da atividade predatória de todos os isolados fúngicos testados, foram observadas ao final de sete dias do experimento, através da recuperação das larvas (L1) não predadas, sendo observados os seguintes percentuais de redução com os respectivos isolados: AC001 (82,8%); CG768 (71,0%); CG722 (72,8%); NF34 (86,7%), SF53 (89,7%); I40 (48,3%), CG719 (84,7%) e I31 (80,4%). Não houve diferença (p>0,01) entre a ação dos isolados utilizados ao final de sete dias, no entanto, foi observado diferença (p<0,01) em relação ao grupo controle. Os resultados demonstraram que os fungos pertencentes aos gêneros Duddingtonia (AC001, CG768 E CG722), Monacrosporium (NF34 e SF53) e Arthrobotrys (I31 e CG719), poderiam ser utilizados no controle biológico, uma vez que estes foram capazes de reduzir a população de larvas (L1) de A. cantonensis in vitro.
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Hüttemann, Maria. "Licht- und elektronenmikroskopische Untersuchungen an Entwicklungsstadien von Angiostrongylus cantonensis und Trichuris muris (Nematodes)." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=97184397X.

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DELAFOREST, CHRISTINE. "La meningite a eosinophiles provoquee par angiostrongylus cantonensis : revue de la litterature." Lyon 1, 1990. http://www.theses.fr/1990LYO1M102.

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Migraine, Bertrand Ghawche Frédéric. "Méningite à éosinophiles en Polynésie à propos de 17 cas /." [S.l.] : [s.n.], 2008. http://castore.univ-nantes.fr/castore/GetOAIRef?idDoc=48161.

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Ramos, Raquel Rocha. "Estudo sobre mol?culas com atividade hemoglobinol?tica em Angiostrongylus costaricensis e Angiostrongylus cantonensis." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2009. http://tede2.pucrs.br/tede2/handle/tede/5341.

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Angiostrongylus costaricensis e A. cantonensis s?o as principais esp?cies patog?nicas para o homem no g?nero Angiostrongylus. Esses parasitos tem tropismo tecidual diferentes, A. cantonensis ? um parasito neurotr?pico que causa a angiostrongil?ase meningoencef?lica e A. costaricensis localiza-se no mesent?rio sendo o agente etiol?gico da angiostrongil?ase abdominal. Os testes imunol?gicos utilizados ultimamente para o diagn?stico das Angiostrongil?ases s?o limitados pela baixa especificidade. Entretanto, prote?nas funcionais especializadas, tais como enzimas, podem ser fontes de reatividade imunol?gica espec?fica. O objetivo do presente trabalho ? identificar atividade hemoglobinol?tica nesses parasitos. Tubos digestivos de f?meas foram homogeneizadas em tamp?o de lise. As prote?nas do extrato (ExAca) foram incubadas com hemoglobina bovina (HbB) em diferentes pHs. Zimografia foi realizado em g?is copolimerizados com 0,4% gelatina ou 0,1% BHb. Degrada??o da hemoglobina foi bem demonstrada em uma ampla faixa de pH, de 3,0 para 7,0. N?o foram detectadas bandas de degrada??o na zimografia com gelatina ou hemoglobina como substrato. Os dados limitados da zimografia e os resultados de atividade hemoglobinol?tica, com ou sem a titula??o de pH, pode sugerir um complexo de proteases em pequena quantidade. Explora??o de diversas estrat?gias de concentra??o do extrato prot?ico, sem perda da atividade da enzima, constitue a perspectiva desse trabalho, visando ? identifica??o, caracteriza??o e produ??o em larga escala de mol?culas com atividade hemoglobinol?tica.
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鄺懿珩 and Yi-hang Agnes Kwong. "Lipid composition and lipases of Angiostrongylus cantonensis (nematoda: metastrongyloidea)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1989. http://hub.hku.hk/bib/B31209208.

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蘇雅頌 and Ngar-chung Nellie So. "Pyrimidine nucleotide biosynthesis in adult angiostrongylus Cantonensis (Nematoda : Metastrongyloidea)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1993. http://hub.hku.hk/bib/B3123320X.

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So, Ngar-chung Nellie. "Pyrimidine nucleotide biosynthesis in adult angiostrongylus Cantonensis (Nematoda : Metastrongyloidea) /." [Hong Kong : University of Hong Kong], 1993. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13637745.

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Books on the topic "Angiostrongylus cantonensis"

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Wang, Qiao-Ping, and Zhao-Rong Lun. Angiostrongylus cantonensis and Human angiostrongylosis. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0066.

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Angiostrongylus cantonensis was first discovered in rats in Guangzhou (Canton), China in 1935 (Chen 1935). A. cantonensis is a zoonotic pathogen, which causes human angiostrongylosis with the main clinical manifestation of eosinophilic meningitis. The first case of human angiostrongylosis was reported in Taiwan in 1945. Subsequently several outbreaks of this disease occurred in Pacific Islands (Rosen et al. 1961; Kliks and Palumbo 1992). In the past decade, a number of outbreaks of human angiostrongylosis have emerged in some endemic regions, especially in China (Wang et al. 2008). Additionally, increasing numbers of travellers are diagnosed with eosinophilic meningitis caused by A. cantonensis after returning from endemic regions (Lo et al. 2001; Slom et al. 2002; Bartschi et al. 2004; Podwall et al. 2004; Kumar et al. 2005; Leone et al. 2007; Ali et al. 2008). The parasite continues to threaten human beings, especially people living in the Pacific Islands and Asia. So far, at least 2,825 cases have been recorded; of them, 1,337 were reported in Thailand, 769 in China (Hong Kong and Taiwan), 256 in Tahiti, 116 in the USA (Hawaii and Samoa) and 114 cases in Cuba (Wang et al. 2008).
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Book chapters on the topic "Angiostrongylus cantonensis"

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Ringelmann, R., and Beate Heym. "Angiostrongylus cantonensis." In Parasiten des Menschen, 83–84. Heidelberg: Steinkopff, 1991. http://dx.doi.org/10.1007/978-3-642-85397-5_14.

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Wei, Jie, and Zhongdao Wu. "Angiostrongylus cantonensis in China." In Treatment of Human Parasitosis in Traditional Chinese Medicine, 215–37. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-39824-7_14.

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"Angiostrongylus cantonensis." In Lexikon der Infektionskrankheiten des Menschen, 31. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-39026-8_55.

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"Angiostrongylus cantonensis." In Encyclopedia of Parasitology, 131–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_188.

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Wattanagoon, Yupaporn, and John H. Cross†. "Eosinophilic Meningitis (Angiostrongylus cantonensis, Parastrongylus cantonensis)." In Hunter's Tropical Medicine and Emerging Infectious Disease, 856–58. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4160-4390-4.00118-1.

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ROSEN, L. "EOSINOPHILIC MENINGITIS AND ANGIOSTRONGYLUS CANTONENSIS IN THE PACIFIC AREA." In Proceedings of the First International Congress of Parasitology, 799–800. Elsevier, 1999. http://dx.doi.org/10.1016/b978-0-08-011427-9.50155-4.

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Lv, Shan, Yun-Hai Guo, Fu-Rong Wei, Yi Zhang, Ning Xiao, and Xiao-Nong Zhou. "Control of eosinopilic meningitis caused by Angiostrongylus cantonensis in China." In Advances in Parasitology, 269–88. Elsevier, 2020. http://dx.doi.org/10.1016/bs.apar.2020.02.002.

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Knight, Richard. "Angiostrongyliasis." In Oxford Textbook of Medicine, edited by Christopher P. Conlon, 1516–19. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0178.

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The rat lungworm Angiostrongylus cantonensis causes outbreaks of eosinophilic meningitis in parts of Southeast Asia, East Asia, Oceania, and the Caribbean. Human infections follow ingestion of raw snails (the primary intermediate hosts), food contaminated by snail mucus, or one of several paratenic hosts. Clinical manifestations include headache, meningism, vomiting, cranial nerve, ocular, lesions, and rarely seizures. Lumbar puncture reveals eosinophilic meningitis and sometimes larval worms. Treatment is usually with prednisolone alone, or with albendazole and prednisolone. Mortality is usually below 2%. Prevention is by avoidance of raw high-risk dietary items and unwashed salads. Another species A. costaricensis causes granulomatous bowel and hepatic lesions in some tropical American countries. Rats are the definiitive hosts, human infection follows ingestion of small slugs. Treatment is surgical.
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ALICATA, J. E. "BIOLOGY AND DISTRIBUTION OF THE RAT LUNGWORM, ANGIOSTRONGYLUS CANTONENSIS, AND ITS RELATION TO EOSINOPHILIC MENINGOENCEPHALITIS AND OTHER NEUROLOGICAL DISORDERS OF MAN AND ANIMALS." In Proceedings of the First International Congress of Parasitology, 826–28. Elsevier, 1999. http://dx.doi.org/10.1016/b978-0-08-011427-9.50179-7.

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Conference papers on the topic "Angiostrongylus cantonensis"

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Maria Zanotti Magalhaes, Eliana, and Cinthia Aparecida Beneton Galeriani. "The use of Ivermectin and DMSO in treatment of Angiostrongyliasis (Angiostrongylus cantonensis) in Wistar rats." In XXIII Congresso de Iniciação Científica da Unicamp. Campinas - SP, Brazil: Galoá, 2015. http://dx.doi.org/10.19146/pibic-2015-38115.

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Ferreira, Patrícia, Paloma Pêgo, André Souza, Arnaldo Maldonado Junior, and Salvatore De Simone. "Estudo imunológico da aspártico protease de Angiostrongylus cantonensis como potencial alvo de testes diagnósticos para a angiostrongilíase humana." In V Seminário Anual Científico e Tecnológico. Instituto de Tecnologia em Imunobiológicos, 2017. http://dx.doi.org/10.35259/isi.sact.2017_26294.

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SOUZA, F. C. R., A. O. BACCIN, and L. C. V. MELO. "AVANÇOS NO DIAGNÓSTICO DA EUROANGIOSTRONGILÍASE: DOS TESTES INTRADÉRMICOS AO SEQUENCIAMENTO GENÔMICO E PESQUISAS COM MIRNA." In III Mostra Dos Trabalhos De Conclusão De Curso Da Especialização Em Vigilância Laboratorial Em Saúde Pública. Agron Science, 2022. http://dx.doi.org/10.53934/101037-2.

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O nematóide Angiostrongylus cantonensis é o principal agente causador da meningite eosinofílica no mundo. Em humanos, a infecção ocorre pela ingestão acidental ou habitual de hospedeiros intermediários ou paratênicos infectados pelo metaestrongilídeo. Entretanto, para fechar um quadro de neuroangiostrongilíase é necessário associar os sintomas clínicos, dados epidemiológicos, presença de eosinofilia e/ou eosinorraquia e encontro de larvas do parasito no LCR, PCR positiva ou exames imunológicos reagentes. Contudo, cada método de diagnóstico apresenta limitações importantes, tratando-se de uma patologia de difícil identificação. Assim, torna-se fundamental a realização de pesquisas que busquem métodos mais efetivos para a execução do diagnóstico laboratorial da patologia. Neste contexto, este trabalho levantou a evolução das técnicas de diagnóstico da neuroangiostrongilíase, reunindo informações que possam auxiliar na introdução desta parasitose no rol de possíveis causas de meningite eosinofílica no Brasil. Além disso, busca também respaldar investigações epidemiológicas, laboratoriais e proporcionar conhecimento aos profissionais da saúde.
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TUSSOLINI, IURY GABRIEL AMAZONAS, GABRIELLE RODRIGUES TUSSOLINI, GABRIELLA FONSECA DE JESUS MESQUITA, DAYENE BUENO CRUVINEL DE LIMA, HIAGO BRUNO CARDOSO COSTA FONSECA, MARIO TERCIO ROCHA JUNIOR, RENAN SOUSA SERRA LIMA, and JOAO FRANCISCO TUSSOLINI. "A RARE CASE OF EOSINOPHYLIC MENINGITIS BY PROBABLE ANGIOSTRONGYLUS CANTONENSIS, IN AN INFANT IN THE CITY OF MANAUS, IN THE AMAZON REGION OF BRAZIL." In I South Florida Congress of Development. CONGRESS PROCEEDINGS I South Florida Congress of Development - 2021, 2021. http://dx.doi.org/10.47172/sfcdv2021-0009.

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March 2021, a 12-month-old infant was brought to the HPS East Zone Little Jonh, in the capital of the State of Amazonas, Brazil, where she was admitted with fever, vomiting, intense prostration, little acceptance of breast milk, difficulty in walking, associated with left-facing strabismus and neck stiffness. At admission, the main author performed a lumbar puncture, and serological tests on the CSF to identify the causative agent were referred to a reference laboratory, which suggested that they be referred to the Central Laboratory - LACEN for suspecting the presence of agent Angionsytrongylis Canyonensis. Although, the identification of the causative agent is difficult to be detected and confirmed, this case report shows us the importance of the clinical laboratory in the identification of Eosinophilic Meningitis. The sub-detection of eosinophils in the CSF helps to underestimate the prevalence of eosinophilic meningitis. Thus, CSF analysis, slide preparation, sediment staining, as well as knowledge about the importance of adequate leukocyte differentiation in CSF are extremely important, to properly conduct the final diagnosis of the disease and prevent possible endemicity. The knowledge of this condition and early detection allows an effective therapy and improvement of public health actions. ? ?,
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TUSSOLINI, IURY GABRIEL AMAZONAS, GABRIELLE RODRIGUES TUSSOLINI, GABRIELLA FONSECA DE JESUS MESQUITA, DAYENE BUENO CRUVINEL DE LIMA, HIAGO BRUNO CARDOSO COSTA FONSECA, MARIO TERCIO ROCHA JUNIOR, RENAN SOUSA SERRA LIMA, and JOAO FRANCISCO TUSSOLINI. "A RARE CASE OF EOSINOPHYLIC MENINGITIS BY PROBABLE ANGIOSTRONGYLUS CANTONENSIS, IN AN INFANT IN THE CITY OF MANAUS, IN THE AMAZON REGION OF BRAZIL." In I South Florida Congress of Development. CONGRESS PROCEEDINGS I South Florida Congress of Development - 2021, 2021. http://dx.doi.org/10.47172/sfcdv2021-0062.

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March 2021, a 12-month-old infant was brought to the HPS East Zone Little Jonh, in the capital of the State of Amazonas, Brazil, where she was admitted with fever, vomiting, intense prostration, little acceptance of breast milk, difficulty in walking, associated with left-facing strabismus and neck stiffness. At admission, the main author performed a lumbar puncture, and serological tests on the CSF to identify the causative agent were referred to a reference laboratory, which suggested that they be referred to the Central Laboratory - LACEN for suspecting the presence of agent Angionsytrongylis Canyonensis. Although, the identification of the causative agent is difficult to be detected and confirmed, this case report shows us the importance of the clinical laboratory in the identification of Eosinophilic Meningitis. The sub-detection of eosinophils in the CSF helps to underestimate the prevalence of eosinophilic meningitis. Thus, CSF analysis, slide preparation, sediment staining, as well as knowledge about the importance of adequate leukocyte differentiation in CSF are extremely important, to properly conduct the final diagnosis of the disease and prevent possible endemicity. The knowledge of this condition and early detection allows an effective therapy and improvement of public health actions. ? ?,
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