To see the other types of publications on this topic, follow the link: Anesthesia Recovery Period.
Journal articles on the topic 'Anesthesia Recovery Period'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Anesthesia Recovery Period.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Talley V, Henry C., Mona N. Wicks, Michael Carter, and Brad Roper. "Ascorbic Acid Does Not Influence Consciousness Recovery After Anesthesia." Biological Research For Nursing 10, no. 3 (November 17, 2008): 292–98. http://dx.doi.org/10.1177/1099800408323222.
Full textAbstract:
Several studies have examined the influence of general anesthesia on changes in consciousness and unconscious cognitive processes. However, much remains to be learned about potential moderators of general anesthetic agents, such as antioxidants including ascorbic acid, and their influence on the recovery of consciousness following general anesthesia. General anesthesia potentially affects plasma ascorbic acid levels and may impair consciousness during the postoperative period; however, published literature regarding these relationships is equivocal. Ascorbic acid is important for brain function and may be related to the return of postoperative consciousness through action on the synaptic receptors in the brain. This study was designed as a pretest—posttest repeated measures investigation. Ascorbic acid levels were measured at four time periods in patients (N = 50) undergoing surgery and general anesthesia. Following surgery, patients were administered a paper-and-pencil measure of concentration that served as an index of post-anesthesia consciousness. The results suggest that changes occur in plasma ascorbic acid levels at different time points during the anesthesia regimen in nonemergent surgical patients. No statistically significant relationships were found between plasma ascorbic acid levels and improved post-anesthesia consciousness, suggesting that ascorbic acid does not influence recovery of consciousness following general anesthesia.
2
Hadžimešić, Munevera, Semir Imamović, Vasvija Uljić, Mirsad Hodžić, Fatima Iljazagić-Halilović, and Renata Hodžić. "Cognitive function recovery rate in early postoperative period: comparison of propofol, sevoflurane and isoflurane anesthesia." Journal of Health Sciences 3, no. 1 (April 15, 2013): 48–54. http://dx.doi.org/10.17532/jhsci.2013.29.
Full textAbstract:
Introduction: There is no simple answer to the question as to when the brain function is back to normal after anaesthesia. Research done so far has identified different factors influencing the rate of cognitive function recovery and type of anaesthetic as one of those factors.Methods: This study encountered 90 patients hospitalized in neurosurgical department of University Clinical Centre Tuzla in period from October 2011 to may 2012 year. Aim of the study was to compare influence of three different anesthetics (propofol, isofl urane and sevofl urane) on recovery rate of cognitive performance 1, 5 and 10 minutes following extubation. Assessment of cognitive functions was preformed using the short Orientation-Memory-Concentration (OMC) Test. All patients included in the study underwent lumbar microdiscectomy surgery and were allocated to one of three groups: propofol, sevoflurane and isoflurane.Results: Trough comparison of OMC test values there is obvious superiority in recovery of cognitive functions between propofol group and inhaled anesthetic group, after 1 minute (p = 0.008) and after 5 minutes (p =0.009). Comparison of propofol and isoflurane anesthesia shows significantly faster recovery of cognitive performance in propofol group (after 1 minute p = 0.002, 5 minutes p = 0.004, 10 minutes p = 0.038). Faster recovery of cognitive function is present in sevoflurane compared to isoflurane group only 1 minute after extubation p = 0.049.Conclusions: Fastest recovery of cognitive performance appears after propofol anesthesia, than follows sevofl urane based anesthesia and after that isoflurane anesthesia.
3
Olfah, Yustiana, Reza Andisa, and Sugeng Jitowiyono. "The Relation of Body Mass Index and Duration of Anesthesia with Conscious Recovery Time in Children with General Anesthesia in Regional General Hospital Central Java Kebumen." Journal of Health 6, no. 1 (January 31, 2019): 58–64. http://dx.doi.org/10.30590/vol6-no1-p58-64.
Full textAbstract:
The calculation of body mass index and duration of anesthesia is the first step of a series of actions performed anesthesia on pediatric patients who planned to undergo anesthesia . The calculation of body mass index and duration of anesthesia determine the smoothness of anesthesia , and the patient's recovery period after general anesthesia. The study is to determine the relationship of body mass index and duration of anesthesia with conscious recovery time after general anesthesia in children using observational analytic cross sectional survey approach. The site of research is in recovery room of The Central Surgery Installation RSUD Kebumen Central Java with as many as 44 research sample consists of body mass index and duration of anesthesia, with postoperative assessment instruments Steward score. The result is patients with conscious recovery time after general anesthesia slowly, over 30 minutes is a patient with a body mass index is not ideal that 13 people ( 68.42 % ) of the total sample whereas patients who recovered quickly in less than or equal to 30 minutes as many as 17 people ( 72 % ) with an ideal tubu mass index of the total sample . From the statistical test Chi-square computer program values obtained value , the probability asymp . Sig . ( 2 - sided ) : 0,008 which means there is a relationship of body mass index of anesthesia with the patient recovery time , and patients recover with time after general anesthesia consciously slowly , over 30 minutes is a patient with a long lebi anesthesia time of 1 hour 12 people ( 75 % ) of the total sample whereas patients who recovered quickly in less than or equal to 30 minutes of 20 people ( 71.43 % ) with a time of anesthesia faster than the total sample . From the statistical test Chi-square computer program values obtained value , the probability asymp. Sig. ( 2 - sided): 0,003 which means there is a long-standing relationship with the anesthesia recovery time of patients, so there is a relationship of body mass index and duration of anesthesia with conscious recovery time
4
Satvaldieva, Elmira A., Otabek Ya Fayziev, and Anvar S. Yusupov. "Multimodal anesthesia and analgesia at the stages of the perioperative period in children with abdominal surgical pathology." Russian Pediatric Journal 24, no. 1 (March 12, 2021): 27–31. http://dx.doi.org/10.46563/1560-9561-2021-24-1-27-31.
Full textAbstract:
Aim of the study was assess both the effectiveness and safety of anesthetic management and optimizing postoperative anesthesia under conditions of multimodal anesthesia and analgesia during abdominal operations in children. Patients and methods. The authors examined 58 children aged 1 to 17 years with abdominal operations (malformations, diseases, and abdominal organ injuries). To ensure anesthetic protection, patients underwent combined general anesthesia with propofol and fentanil (induction) with inhalation of sevoflurane + propofol intra venous (maintenance) in combination with epidural blockade with bupivacaine. Results. According to surgical intervention, the arrangement of perioperative analgesic protection provided a favorable correction of the hemodynamic status of patients, a decrease in inhalation anesthetic, promoted a smooth course of the postoperative period, a long painless period, an excellent psychoemotional background, and rapid postoperative recovery.
5
Galante, Rafaela, Elizabeth Regina Carvalho, José A. P. C. Muniz, Paulo H. G. Castro, Vanessa Nadine Gris, Dorli S. Amora Júnior, and Ricardo G. D’Otaviano C. Vilani. "Comparison between total intravenous anesthesia with propofol and intermittent bolus of tiletamine-zolazepam in capuchin monkey (Sapajus apella)." Pesquisa Veterinária Brasileira 39, no. 4 (April 2019): 271–77. http://dx.doi.org/10.1590/1678-5150-pvb-5847.
Full textAbstract:
ABSTRACT: Dissociative anesthesia results in stressful and long recovery periods in monkeys and use of injectable anesthetics in medical research has to be refined. Propofol has promoted more pleasure wake up from anesthesia. The objectives of this study were to investigate the use of intravenous anesthetic propofol, establishing the required infusion rate to maintain surgical anesthetic level and comparing it to tiletamine-zolazepam anesthesia in Sapajus apella. Eight healthy capuchin monkeys, premedicated with midazolam and meperidine, were anesthetized with propofol (PRO) or tiletamine-zolazepam (TZ) during 60 minutes. Propofol was infused continually and rate was titrated to effect and tiletamine-zolazepam was given at 5mg/kg IV bolus initially and repeated at 2.5mg/kg IV bolus as required. Cardiopulmonary parameters, arterial blood gases, cortisol, lactate and quality and times to recovery were determined. Recovery quality was superior in PRO. Ventral recumbency (PRO = 43.0±21.4 vs TZ = 219.3±139.7 min) and normal ambulation (PRO = 93±27.1 vs TZ = 493.7±47.8 min) were faster in PRO (p<0.05). Cardiopulmonary effects did not have marked differences between groups. Median for induction doses of propofol was 5.9mg/kg, varying from 4.7 to 6.7mg/kg, Mean infusion rate was 0.37±0.11mg/kg/min, varying during the one-hour period. In TZ, two animals required three and five extra doses. Compared to tiletamine-zolazepam, minor post-anesthetic adverse events should be expected with propofol anesthesia due to the faster and superior anesthetic recovery.
6
Tung, Avery, Bernard M. Bergmann, Stacy Herrera, Dingcai Cao, and Wallace B. Mendelson. "Recovery from Sleep Deprivation Occurs during Propofol Anesthesia." Anesthesiology 100, no. 6 (June 1, 2004): 1419–26. http://dx.doi.org/10.1097/00000542-200406000-00014.
Full textAbstract:
Background Some neurophysiologic similarities between sleep and anesthesia suggest that an anesthetized state may reverse effects of sleep deprivation. The effect of anesthesia on sleep homeostasis, however, is unknown. To test the hypothesis that recovery from sleep deprivation occurs during anesthesia, the authors followed 24 h of sleep deprivation in the rat with a 6-h period of either ad libitum sleep or propofol anesthesia, and compared subsequent sleep characteristics. Methods With animal care committee approval, electroencephalographic/electromyographic electrodes and intrajugular cannulae were implanted in 32 rats. After a 7-day recovery and 24-h baseline electroencephalographic/electromyographic recording period, rats were sleep deprived for 24 h by the disk-over-water method. Rats then underwent 6 h of either propofol anesthesia (n = 16) or ad libitum sleep with intralipid administration (n = 16), followed by electroencephalographic/electromyographic monitoring for 72 h. Results In control rats, increases above baseline in non-rapid eye movement sleep, rapid eye movement sleep, and non-rapid eye movement delta power persisted for 12 h after 24 h of sleep deprivation. Recovery from sleep deprivation in anesthetized rats was similar in timing to that of controls. No delayed rebound effects were observed in either group for 72 h after deprivation. Conclusion These data show that a recovery process similar to that occurring during naturally occurring sleep also takes place during anesthesia and suggest that sleep and anesthesia share common regulatory mechanisms. Such interactions between sleep and anesthesia may allow anesthesiologists to better understand a potentially important source of variability in anesthetic action and raise the possibility that anesthetics may facilitate sleep in environments where sleep deprivation is common.
7
Hickman, Leonard Brian, ShiNung Ching, Mathias Basner, Wei Wang, Nan Lin, Max Kelz, George Mashour, Michael S. Avidan, and Ben J. A. Palanca. "3147 Electroencephalographic suppression from anesthesia and cognitive recovery." Journal of Clinical and Translational Science 3, s1 (March 2019): 104. http://dx.doi.org/10.1017/cts.2019.237.
Full textAbstract:
OBJECTIVES/SPECIFIC AIMS: (1) Assess if the total duration of EEG suppression during a protocolized exposure to general anesthesia predicts cognitive performance in multiple cognitive domains immediately following emergence from anesthesia. (2) Assess if the total duration of EEG suppression in the same individuals predicts the rate of cognitive recovery in a three-hour period following emergence from anesthesia. METHODS/STUDY POPULATION: This was a non-specified substudy of NCT01911195, a multicenter investigation taking place at the University of Michigan, University of Pennsylvania, and Washington University in St. Louis. 30 healthy volunteers aged 20-40 years were recruited to receive general anesthesia. Participants in the anesthesia arm were anesthetized for three hours at isoflurane levels compatible with surgery (1.3 MAC). Multichannel sensor nets were used for EEG acquisition during the anesthetic exposure. EEG suppression was detected through automated voltage-thresholded classification of 2-second signal epochs, with concordance assessed across sensors. Following return of responsiveness to verbal commands, participants completed up to three hours of serial cognitive tests assessing executive function, reaction time, cognitive throughput, and working memory. Non-linear mixed effects models will be used to estimate the initial cognitive deficit and the rate of cognitive recovery following anesthetic exposure; these measures of cognitive function will be assessed in relation to total duration of suppression during anesthesia. RESULTS/ANTICIPATED RESULTS: Participants displayed wide variability in the total amount of suppression during anesthesia, with a median of 31.2 minutes and range from 0 minutes to 115.2 minutes. Initial analyses suggest that greater duration of burst suppression had a weak relationship with participants’ initial cognitive deficits upon return of responsiveness from anesthesia. Model generation of rate of recovery following anesthetic exposure is pending, but we anticipate this will also have a weak relationship with burst suppression. DISCUSSION/SIGNIFICANCE OF IMPACT: In healthy adults receiving a standardized exposure to anesthesia without surgery, burst suppression appears to be a poor predictor of post-anesthesia cognitive task performance. This suggests that burst suppression may have limited utility as a predictive marker of post-operative cognitive functioning, particularly in young adults without significant illness.
8
Whitehair, Karen J., Eugene P. Steffey, Neil H. Willits, and Michael J. Woliner. "Recovery of horses from inhalation anesthesia." American Journal of Veterinary Research 54, no. 10 (October 1, 1993): 1693–702. http://dx.doi.org/10.2460/ajvr.1993.54.10.1693.
Full textAbstract:
Summary To study behavioral and cardiopulmonary characteristics of horses recovering from inhalation anesthesia, 6 nonmedicated horses were anesthetized under laboratory conditions on 3 different days, with either halothane or isoflurane in O2. Anesthesia was maintained at constant dose (1.5 times the minimum alveolar concentration [mac]) of halothane in O2 for 1 hour (H1), halothane in O2 for 3 hours (H3), or isoflurane in O2 for 3 hours (I3). The order of exposure was set up as a pair of Latin squares to account for horse and trial effects. Circulatory (arterial blood pressure and heart rate) and respiratory (frequency, PaCO2, PaO2, pHa) variables were monitored during anesthesia and for as long as possible during the recovery period. End-tidal percentage of the inhaled agent was measured every 15 seconds by automated mass spectrometry, then by hand-sampling after horses started moving. Times of recovery events, including movement of the eyelids, ears, head, and limbs, head lift, chewing, swallowing, first sternal posture and stand attempts, and the number of sternal posture and stand attempts, were recorded. The washout curve or the et ratio (end-tidal percentage of the inhaled agent at time t to end-tidal percentage of the inhaled agent at the time the anesthesia circuit was disconnected from the tracheal tube) plotted against time was similar for H1 and H3. The slower, then faster (compared with halothane groups) washout curve of isoflurane was explainable by changes in respiratory frequency as horses awakened and by lower blood/gas solubility of isoflurane. The respiratory depressant effects of isoflurane were marked and were more progressive than those for halothane at the same 1.5 mac dose. During the first 15 minutes of recovery, respiratory frequency for group-I3 horses increased significantly (P < 0.05), compared with that for the halothane groups. For all groups, arterial blood pressure increased throughout the early recovery period and heart rate remained constant. Preanesthesia temperament of horses and the inhalation agent used did not influence the time of the early recovery events (movement of eyelids, ears, head, and limbs), except for head lift. For events that occurred at anesthetic end-tidal percentage < 0.20, or when horses were awake, temperament was the only factor that significantly influenced the nature of the recovery (chewing P = 0.04, extubation P = 0.001, first stand attempt P = 0.008, and standing P = 0.005). The quality of the recoveries did not differ significantly among groups (H1, H3, I3) or horses; however 5 of 6 horses recovering from the H1 exposure had ideal recovery. During recovery, the anesthetic end-tidal percentage did not differ significantly among groups. However, when concentrations were compared on the basis of anesthetic potency (ie, mac multiple) a significantly (P < 0.05) lower MAC multiple of isoflurane was measured for the events ear movement, limb movement, head lift, and first attempt to sternal posture, compared with that for horses given halothane, indicating that isoflurane may be a more-potent sedative than halothane in these horses.
9
Alshkarchy, Samer Saleem, Khalidah S. Al-Niaeem, and Raaed Sami Attee. "Assessment of Valerian (Valeriana officinalis) on Common Carp, Cyprinus carpio: Anesthesia." IOP Conference Series: Earth and Environmental Science 1215, no. 1 (July 1, 2023): 012061. http://dx.doi.org/10.1088/1755-1315/1215/1/012061.
Full textAbstract:
Abstract The anesthetic efficacy of Valerian (Valeriana officinalis) powders was evaluated on common carp (Cyprinus carpio L.) The following concentrations (250, 350, 450) mg/liter were used in three replicates. During the experiment, the period required for partial and total anesthesia and the time required for partial and total recovery was tested, as well as the number of red and white blood cells after and before Anesthesia in addition to blood serum enzymes represented (ALP, GOT, GPT, CK, and LDH in Ul / l). The results showed that the least period of anesthesia occurred in the fourth treatment, the treatment with a concentration of 450 mg / l, as well as the least period required for recovery, while the recovery period was the longest. And anesthesia in the first treatment exposed to a concentration of 250 mg/liter, and it was not noticed that there was a significant difference between each the number of red blood cells, white blood cells in the test fish before the experiment and after treatment with valerian plants, as well as each of (ALP, GOT, GPT, CK, and LDH in Ul / l) There were no significant differences between all treatments before and after exposure to valerian, and it is concluded from the study that valerian is a safe plant for use in anesthetizing fish.
10
Neumann, Mireille A., Richard B. Weiskopf, Diane H. Gong, Edmond I. Eger, and Pompiliu Ionescu. "Changing from Isoflurane to Desflurane toward the End of Anesthesia Does Not Accelerate Recovery in Humans." Anesthesiology 88, no. 4 (April 1, 1998): 914–21. http://dx.doi.org/10.1097/00000542-199804000-00010.
Full textAbstract:
Background In an attempt to combine the advantage of the lower solubilities of new inhaled anesthetics with the lesser cost of older anesthetics, some clinicians substitute the former for the latter toward the end of anesthesia. The authors tried to determine whether substituting desflurane for isoflurane in the last 30 min of a 120-min anesthetic would accelerate recovery. Methods Five volunteers were anesthetized three times for 2 h using a fresh gas inflow of 2 l/min: 1.25 minimum alveolar concentration (MAC) desflurane, 1.25 MAC isoflurane, and 1.25 MAC isoflurane for 90 min followed by 30 min of desflurane concentrations sufficient to achieve a total of 1.25 MAC equivalent ("crossover"). Recovery from anesthesia was assessed by the time to respond to commands, by orientation, and by tests of cognitive function. Results Compared with isoflurane, the crossover technique did not accelerate early or late recovery (P > 0.05). Recovery from isoflurane or the crossover anesthetic was significantly longer than after desflurane (P < 0.05). Times to response to commands for isoflurane, the crossover anesthetic, and desflurane were 23 +/- 5 min (mean +/- SD), 21 +/- 5 min, and 11 +/- 1 min, respectively, and to orientation the times were 27 +/- 7 min, 25 +/- 5 min, and 13 +/- 2 min, respectively. Cognitive test performance returned to reference values 15-30 min sooner after desflurane than after isoflurane or the crossover anesthetic. Isoflurane cognitive test performance did not differ from that with the crossover anesthetic at any time. Conclusions Substituting desflurane for isoflurane during the latter part of anesthesia does not improve recovery, in part because partial rebreathing through a semiclosed circuit limits elimination of isoflurane during the crossover period. Although higher fresh gas flow during the crossover period would speed isoflurane elimination, the amount of desflurane used and, therefore, the cost would increase.
11
Marova, N. G., Ya I. Vasilyev, E. V. Klyushnikova, A. V. Kononov, and T. S. Polyakova. "LOCAL ANESTHESIA FOR VITREO-RETINAL SURGERY." Regional Anesthesia and Acute Pain Management 12, no. 1 (March 15, 2018): 24–29. http://dx.doi.org/10.18821/1993-6508-2018-12-1-24-29.
Full textAbstract:
Local anesthesia is used as a component of general anesthesia or self-sufficient technique of perioperative analgesia at the vitreo-retinal surgery. Its popularity originates from safety and simplicity of regional techniques which provide efficient analgesia, perfect surgical field and fast recovery. Most of injection techniques of ophthalmic regional anesthesia are single shot methods which could not provide effective analgesia in some patients who required anesthesia for a prolonged period. Implementation of catheter technique in daily practice could be solution to this problem. Infusion of local anesthetic through catheter possesses all advantages of single-shot techniques and provides virtually unlimited duration of analgesia.
12
Guerrero, Jesus Leonardo Suarez, Pedro Henrique Salles Brito, Marília Alves Ferreira, Julia de Assis Arantes, Elidiane Rusch, Brenda Valéria dos Santos Oliveira, Juan Velasco-Bolaños, Adriano Bonfim Carregaro, and Renata Gebara Sampaio Dória. "Evaluation of Gastric pH and Gastrin Concentrations in Horses Subjected to General Inhalation Anesthesia in Dorsal Recumbency." Animals 14, no. 8 (April 15, 2024): 1183. http://dx.doi.org/10.3390/ani14081183.
Full textAbstract:
The prevalence of gastric disorders in high-performance horses, especially gastric ulceration, ranges from 50 to 90%. These pathological conditions have negative impacts on athletic performance and health. This study was designed to evaluate changes in gastric pH during a 24 h period and to compare gastrin concentrations at different time points in horses undergoing general inhalation anesthesia and dorsal recumbency. Twenty-two mixed-breed mares weighing 400 ± 50 kg and aged 8 ± 2 years were used. Of these, eight were fasted for 8 h and submitted to 90 min of general inhalation anesthesia in dorsal recumbency. Gastric juice samples were collected prior to anesthesia (T0), and then at 15 min intervals during anesthesia (T15–T90). After recovery from anesthesia (45 ± 1 min), samples were collected every hour for 24 h (T1 to T24) for gastric juice pH measurement. During this period, mares had free access to Bermuda grass hay and water and were fed a commercial concentrate twice (T4 and T16). In a second group (control), four non-anesthetized mares were submitted to 8 h of fasting followed by nasogastric intubation. Gastric juice samples were then collected at T0, T15, T30, T45, T60, T75, and T90. During this period, mares did not receive food or water. After 45 min, mares had free access to Bermuda grass hay and water, and gastric juice samples were collected every hour for four hours (T1 to T4). In a third group comprising ten non-fasted, non-anesthetized mares with free access to Bermuda grass hay and water, gastric juice samples were collected 30 min after concentrate intake (T0). In anesthetized mares, blood gastrin levels were measured prior to anesthesia (8 h fasting; baseline), during recovery from anesthesia, and 4 months after the anesthetic procedure, 90 min after the morning meal. Mean values of gastric juice pH remained acidic during general anesthesia. Mean pH values were within the physiological range (4.52 ± 1.69) and did not differ significantly between time points (T15–T90; p > 0.05). After recovery from anesthesia, mean gastric pH values increased and remained in the alkaline range throughout the 24 h period of evaluation. Significant differences were observed between T0 (4.88 ± 2.38), T5 (7.08 ± 0.89), T8 (7.43 ± 0.22), T9 (7.28 ± 0.36), T11 (7.26 ± 0.71), T13 (6.74 ± 0.90), and T17 (6.94 ± 1.04) (p < 0.05). The mean gastric juice pH ranged from weakly acidic to neutral or weakly alkaline in all groups, regardless of food and water intake (i.e., in the fasted, non-fasted, and fed states). Mean gastric pH measured in the control group did not differ from values measured during the 24 h post-anesthesia period or in the non-fasted group. Gastrin concentrations increased significantly during the post-anesthetic period compared to baseline (20.15 ± 7.65 pg/mL and 15.15 ± 3.82 pg/mL respectively; p < 0.05). General inhalation anesthesia and dorsal recumbency did not affect gastric juice pH, which remained acidic and within the physiological range. Gastric juice pH was weakly alkaline after recovery from anesthesia and in the fasted and fed states. Serum gastrin levels increased in response to general inhalation anesthesia in dorsal recumbency and were not influenced by fasting. Preventive pharmacological measures are not required in horses submitted to general anesthesia and dorsal recumbency.
13
McLain, Robert F., Iain Kalfas, Gordon R. Bell, John E. Tetzlaff, Helen J. Yoon, and Maunak Rana. "Comparison of spinal and general anesthesia in lumbar laminectomy surgery: a case-controlled analysis of 400 patients." Journal of Neurosurgery: Spine 2, no. 1 (January 2005): 17–22. http://dx.doi.org/10.3171/spi.2005.2.1.0017.
Full textAbstract:
Object. Despite a history of safety and efficacy, spinal anesthesia is rarely used in lumbar surgery. Application of regional anesthetics is widely preferred for lower-extremity surgery, but general anesthesia is used almost exclusively in spine surgery, despite evidence that spinal anesthesia is as safe and may offer some advantages. Methods. In this case-controlled study the authors analyzed outcomes obtained in 400 patients in whom either spinal anesthesia or general anesthesia was induced to perform a lumbar decompression. Patients were matched for anesthesia-related class, preoperative diagnosis, surgical procedure, and perioperative protocols. All aspects of surgery, recovery, postanesthesia care, and pain management were uniform irrespective of the anesthetic type. Case complexity was equivalent. An independent observer performed analysis of the data. Data from the intraoperative period through hospital discharge were collected and compared. Two hundred consecutive patients meeting inclusion criteria were included in each group. Patients were treated for either lumbar stenosis or herniated nucleus pulposus. Demographically, both groups were well matched. Anesthetic and operative times were longer for patients receiving a general anesthetic (p < 0.05), in whom more nausea and greater requirements for antiemetics and pain medication were also present during recovery (p < 0.05). Overall complication rates and, specifically, the incidences of urinary retention were significantly lower in spinal anesthesia—induced patients (p < 0.05). There were no neural injuries in either group, and the incidence of spinal headache was lower in patients receiving a spinal anesthetic (1.5% compared with 3%). Conclusions. Spinal anesthesia was as safe and effective as general anethesia for patients undergoing lumbar laminectomy. Potential advantages of spinal anesthsia include a shorter anesthesia duration, decreased nausea, antiemetic and analgesic requirements, and fewer complications. Successful surgery can be performed using either anesthesia type.
14
Sumin, S. A., N. A. Volkova, V. P. Mikhin, E. N. Bogoslovskaya, and P. A. Eremin. "ARMYTHMIC ACTIVITY OF MYOCARDIUM AT DIFFERENT STAGES OF ANESTHESIA AND PERI-OPERATIVE PERIOD IN PATIENTS UNDERGOING CHOLECYSTECTOMY." Messenger of ANESTHESIOLOGY AND RESUSCITATION 16, no. 1 (February 21, 2019): 24–48. http://dx.doi.org/10.21292/2078-5658-2019-16-1-24-48.
Full textAbstract:
Prevention of cardiovascular complications, which often result in fatal events in the peri-operative period, is one of the most crucial issues of modern anesthesiology.The objective: to investigate the changes in arrhythmic activity and conduction disorders during anesthesia and in the peri-operative period in the patients undergoing open cholecystectomy under general anesthesia.Subjects and methods. 57 patients of 60.1 ± 3.8 years old were enrolled in the study; they all underwent planned open cholecystectomy under combined anesthesia with tracheal intubation and artificial pulmonary ventilation. Group 1 consisted of 28 patients suffering from coronary heart disease (CHD) in the form of exertional angina of functional classes of I and II; and Group 2 included 29 patients without CHD. The frequency of episodes of group and polymorphic premature ventricular contractions, supraventricular tachycardia and atrioventricular block of degree II, was analyzed by daily Holter ECG monitoring for certain time periods during anesthesia and the peri-operative period. Stages of the study: I – on the eve of the surgery (18 h); II – within 6 hours before the surgery; III – immediate preparation and induction of anesthesia (62.0 ± 6.7 min); IV – maintenance of anesthesia (57 ± 14 min); V – recovery from anesthesia (48 ± 11 min); VI – the 2nd day after surgery (18 h).Results. A significant increase in the frequency of episodes of group and polymorphic premature ventricular contractions, supraventricular tachycardia and atrioventricular block of degree II, was found out at the stages of induction, maintenance and recovery from anesthesia in patients with CHD and in patients without concurrent cardiovascular disorders. Increased frequency of episodes of group and polymorphic premature ventricular contractions was observed in patients with CHD at the stages of induction and recovery from anesthesia (by 242 and 225%). The highest increase in the frequency of polymorphic premature ventricular contractions was observed in patients with CHD during recovery from anesthesia (by 284%) and in those without cardiovascular pathology at the induction stage (by 461%); the increase in episodes of supraventricular tachycardia was maximum at the induction stage in the patients without cardiovascular pathology (by 291%).Conclusion: Open cholecystectomy in general anesthesia is associated with increased arrhythmic activity and higher conduction disturbances incidence at all stages of anesthesia in patients with coronary heart disease and those without concurrent cardiovascular disorders.
15
Şen, Zeynep Bilgen, and Nuh Kiliç. "General Anesthesia in Geriatric Dogs with Propofol-Isoflurane, PropofolSevoflurane, Alphaxalone-Isoflurane, Alphaxalone-Sevoflurane and Their Comparison of Biochemical, Hemodynamic and Cardiopulmonary Effects." Acta Scientiae Veterinariae 46, no. 1 (May 16, 2018): 9. http://dx.doi.org/10.22456/1679-9216.81800.
Full textAbstract:
Background: Geriatric is defined as the life-cycle in which the physical state, organ functions, sensory functions, mental function and immunity progressively regress. Aging causes progressive and irreversible changes in the functional capacities of organ systems, which in turn alter the response to stress and anesthetic drugs. Propofol is an anesthetic agent with sedative and hypnotic effects. Anesthesia induction with propofol is fast and smooth. Alphaxalone (3α-hydroxy-5α-pregnane11,20-dione) is a central nervous system depressant in the form of synthetic neuroactive steroids. This allows anesthesia and muscle relaxation by increasing the inhibition of gamma amino butyric acid type A (GABA) receptors. The aim of this study is to compare effects of propofol-isoflurane and propofol-sevoflurane with relatively a new anesthetic combination alphaxalone-isoflurane and alphaxalone-sevoflurane on hematological, biochemical and physiological parameters.Materials, Methods & Results: Dogs were randomly divided into 4 groups and anesthesia protocols were applied. After induction of anesthesia with 6 mg/kg propofol in groups 1 and 2, isoflurane anesthesia was continued in group 1 and sevoflurane in group 2. After induction of 3 mg/kg alphaxalone anesthesia in groups 3 and 4, isoflurane anesthesia was continued in group 3 whereas sevoflurane in group 4. Vena cephalica was catheterized for blood collection. At the preanesthetic period, 15, 30, 45, 60 min and 60 min after the anesthesia, complete blood counts were performed. Serum ALT, AST, urea, creatinine values were measured during preanesthesia, perianesthesia 15-30 min and 60 min after anesthesia. Cardiopulmonary parameters and reflexes were evaluated before anesthesia and recorded at perianesthetic 5, 10, 15, 30, 45, 60 min and 60 min after full recovery. Patients were monitored during anesthesia. The average age of the dogs in the study was 10.83. All of the dogs were anesthetized in a few seconds with intravenous injection of propofol or alphaxalone. During anesthesia the respiratory rate (fR) was recorded by counting the movements of the reservoir bag. A pulse oximeter was used to monitor pulse rate (fH) and haemoglobin oxygen saturation (SpO2). Body temperature was measured from rectum with a thermometer. Geriatric dogs were anesthetized for a variety of clinical reasons, concerning laparatomy (12.5%), orthopedic (7.5%), soft tissue (60%), dental (10%) and ophthalmologic surgery (10%). Duration of anesthesia was 94.44 (± 12.6) for group I, 81(± 10.54) for group II, 93.88 (± 11.6) for group III and 64.5 (± 3.97) min for group IV. Serum urea and creatinine concentrations were not significantly different in the four groups.Discussion: The mean duration of anesthesia recovery was 6.0 ± 2.0 in group 1, 4.6 ± 1.45 in group 2, 3.7 ± 1.23 in group 3 and 9.7 ± 3.09 min in group 4. In group 4 recovery was longer than other groups and statistically significant (P < 0.05). In our research, the recovery is shorter in the isoflurane treated groups than in the sevoflurane treated groups. When the effect of different groups on heart rate was examined, the difference between them was not significant. Duration and depth of the anesthesia with propofol-isoflurane, propofol-sevoflurane, alphaxalone–isoflurane and alphaxalone-sevoflurane were found to be satisfactory for surgery. Four anesthetic agents applied in geriatric dogs did not adversely affected the hematological and biochemical parameters. In conclusion anesthesia on geriatric dogs after induction of propofol and alphaxalone maintained with isoflurane or sevoflurane found to be safe. However, they did not provide analgesia in painful operations, so it would be appropriate to use analgesics in the pre or intraoperative period.
16
SIDDIQI, K. J., and F. A. KHAN. "A Prospective Study of Post anaesthesia Recovery Room Complications: Incidence and Treatment." Annals of King Edward Medical University 13, no. 1 (November 18, 2021): 88–93. http://dx.doi.org/10.21649/akemu.v13i1.4781.
Full textAbstract:
Objectives: To audit the incidence and nature of post-anesthesia recovery room complications, their treatment and review the role of recovery room in modern anesthetic practice. Methods: 3151 patients who received general or regional anaesthesia were admitted to the recovery room during six months period (August 01, 1995 to January 31, 1996). Information noted on forms by recovery nurse by encircling the pre coded complication. Result: Out of 3151 patients, 2716 patient's data forms could be collected. Therefore results reflect 86% of the patients passing through the recovery. The overall incidence of complications in our population was 36.26%.Complications referable to CNS were 52.29%, the commonest of which was pain[51.26%], agitation (0.18%) and excessive drowsiness (1.01%).The second commonest system was GIT(25.07%) nausea (14.31%) and vomiting (12.18%). The third system was CVS (21.52%), bradycardia (5.48%), tachycardia (7.61%), hypertension (4.26%), hypotension (2.53%) ,myocardial ischaemia (0.81%) myocardia infarction (0.10%) and new arrhythmias (1.41%).The fourth system was Respiratory system (5.58%), hypoventilation (1.42%), bronchospasm (0.81%), and Desaturation (Sp02 < 90%) in (0.1%).0.6% patients had to be re-intubated. Two patients had oliguria. Miscellaneous complications were (9.94%). More than one complication was observed in some patients. The incidence of mortality in our study during this period was 0.10%. Conclusion: Every third patient is susceptible to get some form of complications in the immediate post-anesthesia recovery period. It reflects the importance and need of a specialized designated area called recovery room with qualified staff.
17
Pogorelov, M. A., A. A. Stekolnikov, and A. V. Zaytseva. "The use of lidocaine during anesthesiological support, in the surgical treatment of inversion of the large colon in horses." International Journal of Veterinary Medicine, no. 2 (June 29, 2023): 372–78. http://dx.doi.org/10.52419/issn2072-2419.2023.2.372.
Full textAbstract:
Volvulus of the large colon is one of the most severe diseases of the gastrointestinal tract in horses. Without surgical treatment of this pathology, the mortality of horses reaches 100%. The success of surgical treatment depends on the complexity of the pathology, the time since the onset of the disease, the patient's condition before surgery. Operations in this pathology are impossible without general multimodal anesthesia. However, the anesthetic support of such patients is often accompanied by a large number of complications due to hemodynamic and metabolic disorders in the body, as a result of strangulation and stretching of the intestinal wall, abdominal compartment syndrome, as well as the impossibility of full stabilization of the patient's condition due to the need to perform the operation as soon as possible. This article discusses our experience of anesthetic management in the surgical treatment of horses diagnosed with volvulus of the large colon with and without lidocaine, the effect of lidocaine on the patient's condition during general anesthesia, recovery from anesthesia, and the occurrence of postoperative complications. The material for the article was data from twelve patients who underwent surgery for the elimination of volvulus of the large colon at the Forside Veterinary Clinic in the period 2021-2023. During the analysis of the data obtained, it was revealed that with the inclusion of infusion at a constant rate of lidocaine at a dosage of 2 mg/kg per hour in the protocol of multimodal anesthesia, the concentration of isoflurane decreased by an average of 1%, and the use of tiletamine-zolazepam became irrelevant. This made it possible to reduce the time of recovery from anesthesia and recovery of patients in the soft box, as well as the number of postoperative complications associated with general anesthesia, such as paralytic ileus and myopathy, even in patients with severe hemodynamic disturbances in the preoperative period. A lethal outcome was recorded in two out of six operated horses, in the anesthetic protocol of which lidocaine was not used. In patients with the use of lidocaine in the anesthesia protocol, a lethal outcome was recorded in one case out of six. Thus, after the inclusion of constant-rate infusion of lidocaine into the anesthesia protocol, the mortality rate was halved, from 30 to 15%.
18
Hameed, Falah Mahmood, Fateh Kadhim, Hayder Mohammed Mohsen Al-Tomah, and Raeed Altaee. "A Rabbit Clinical Trial of Xylazine-Ketamine vs. Fentanyl-Ketamine for General Anesthesia." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 11 (May 16, 2024): 285–93. http://dx.doi.org/10.56557/upjoz/2024/v45i114096.
Full textAbstract:
The Aim of Study: The current investigation was designed to compare the anesthetic and physiological effects of ketamine with different pre-anesthetics protocol. Methods: A total of twelve healthy male rabbits were chosen for the clinical anesthetic trial. Animals were presented to the faculty of veterinary medicine at Kerbala University for skin wound procedures and separated into two equal groups 6 rabbits each (group A and group B). Rabbits in group A were administered an intramuscular injection of xylazine (10mg/kg BW) followed by ketamine (50 mg/kg I.M) after 10 minutes. while those in group B were injected with fentanyl (0.04 mg/kg BW, I.M) first plus ketamine (50 mg/kg I.M) after 10 minutes. The physiological and anesthetic parameters to assess the complications that associated with anesthetic, were recorded and analyzed. Results: The level of induction and recovery varied significantly (P<0.05) among the groups. Compared to group B, group A had a considerably (P<0.05) shorter induction time. Furthermore, group A's mean time for losing pedal reflex revealed a substantial (P<0.05) decrease. Between-group differences in the responses to the pain test and muscular relaxation were statistically significant (P<0.05). Group A experienced a substantially longer (P<0.05) induction period, surgical anesthetic duration, and recovery period than group B. No rabbits died as a result of the anesthetic or the recuperation. Conclusion: Compared to Fentanyl-ketamine (FK) combination anesthesia, administration of Xylazine with ketamine (XK) apparently does not influence the physiological parameters. Additionally, this method provides a very successful anesthetic procedure for a flawless induction, suitable muscle relaxation, extended anesthesia, and a painless recovery.
19
Bednarski, Richard, Kurt Grimm, Ralph Harvey, Victoria M. Lukasik, W. Sean Penn, Brett Sargent, and Kim Spelts. "AAHA Anesthesia Guidelines for Dogs and Cats*." Journal of the American Animal Hospital Association 47, no. 6 (November 1, 2011): 377–85. http://dx.doi.org/10.5326/jaaha-ms-5846.
Full textAbstract:
Safe and effective anesthesia of dogs and cats rely on preanesthetic patient assessment and preparation. Patients should be premedicated with drugs that provide sedation and analgesia prior to anesthetic induction with drugs that allow endotracheal intubation. Maintenance is typically with a volatile anesthetic such as isoflurane or sevoflurane delivered via an endotracheal tube. In addition, local anesthetic nerve blocks; epidural administration of opioids; and constant rate infusions of lidocaine, ketamine, and opioids are useful to enhance analgesia. Cardiovascular, respiratory, and central nervous system functions are continuously monitored so that anesthetic depth can be modified as needed. Emergency drugs and equipment, as well as an action plan for their use, should be available throughout the perianesthetic period. Additionally, intravenous access and crystalloid or colloids are administered to maintain circulating blood volume. Someone trained in the detection of recovery abnormalities should monitor patients throughout recovery. Postoperatively attention is given to body temperature, level of sedation, and appropriate analgesia.
20
Zheng, Zhihuan, Ke Ding, Zhengyan Tang, Ziqiang Wu, Zhongyi Li, Guilin Wang, Benyi Fan, and Zhao Wang. "Anesthesia Analysis of Compound Lidocaine Cream Alone in Adult Male Device-Assisted Circumcision." Journal of Clinical Medicine 12, no. 9 (April 25, 2023): 3121. http://dx.doi.org/10.3390/jcm12093121.
Full textAbstract:
Objective: to evaluate the anesthetic effect among adult male patients with the single use of compound lidocaine cream in device-assisted circumcision, hoping to provide an anesthetic method for the simplification of the surgical process. Methods: Male adult patients undergoing device-assisted circumcision through prepuce local anesthesia using lidocaine cream in Xiangya Hospital of Central South University from December 2020 to August 2021 were selected. According to different age groups and different surgical procedures, the anesthetic effect of compound lidocaine cream was analyzed considering the aspects of anesthetic cost, anesthetic time, anesthetic duration, anesthetic effect, anesthetic side effects and anesthetic satisfaction. Results: In the study, 99.1% of 649 patients needed only 1 application of compound lidocaine cream to complete the operation. The time taken for anesthesia was short; the whole anesthesia process only required approximately 2–5 min. However, for patients with severe phimosis, the time to complete the anesthesia procedure was correspondingly longer. The pain degree caused by anesthesia was low, and the patients with a pain score of ≤3 points accounted for 96.7%. The anesthetic effect lasted for a sufficiently long period, and the time of algesia recovery from local anesthesia was almost 1 h after surgery. The anesthesia effect was sufficient, and patients with an intraoperative pain score of ≤3 accounted for 98.7%, which could meet the surgical requirements. There were few side effects of the anesthesia. The overwhelming majority of patients were pleased with the anesthesia, and 98.9% of patients had an anesthesia satisfaction score of ≥7. Conclusion: The compound lidocaine cream, as a local anesthetic, is safe and effective for most adult male device-assisted circumcisions. More useful information needs to be corroborated by more advanced evidence, especially for severe phimosis.
21
Xuan, Hongmei, and Keping Xu. "Warning and Nursing Experience of Anesthesia Depth Monitoring for Patients with General Anesthesia Delayed to Leave Anesthesia Recovery Room and Delirium." Emergency Medicine International 2022 (November 10, 2022): 1–5. http://dx.doi.org/10.1155/2022/3610838.
Full textAbstract:
Affected by the residues of narcotic drugs, patients under general anesthesia are vulnerable to emergence of agitation, delirium, hemodynamic changes, and other adverse events in the recovery period of anesthesia. Therefore, it is necessary to strengthen the observation and care of these patients. Depth of anesthesia monitoring (DAM) has always been a concern for anesthesiologists, but there are few reports related to it. This study compared the early warning value of DAM for patients under general anesthesia with delayed exit from the anesthesia recovery unit (PACU) and delirium and summarized the related nursing experience. The results showed that DAM could reduce the incidence of complications in patients under general anesthesia, reduce the incidence of delirium, shorten the time of postoperative anesthesia recovery and PACU observation time, reduce the workload of nursing staff, and improve nursing satisfaction. DAM plays an important role in improving the quality and efficiency of care in PACU.
22
Al-Hyani, O. H. "Comparison between tow techniques for induction of general anesthesia : popofol –fentanyl and ketamine fentanyl in dogs." Al-Qadisiyah Journal of Veterinary Medicine Sciences 9, no. 1 (June 20, 2010): 12. http://dx.doi.org/10.29079/vol9iss1art87.
Full textAbstract:
This study was conducted to evaluate the anesthetic quality between propofol-fentanyl mixture (P-F)(2 mg/kg+0.004 mg/kg, i.v., respectively)and ketamine-fentanyl mixture (K-F)(10 mg/kg+0.004 mg/kg, i.v., respectively) in six adult dogs premedicated with atropine (0.05 mg/kg, i.m.) and xylazine (2 mg/kg, i.m.).The results revealed the presence of significant difference (p< 0.05) only in the induction of anesthesia, recovery and standing period between both protocols.P-F mixture produced rapid, smooth and free of excitement induction (9.50 ± 0.76 sec) with transit apnea (19.16±2.4 sec). The duration of anesthesia was (23.33 ± 2.10 min), narcosis (32.50± 1.70 min) and anesthesia characterized by good muscle relaxation and abolishment of all reflexes with decrease in R.R. and increase in H R. Recovery was calm and rapid (46.6±2.25 min) and standing time was short (14.16±1.40 min),While anesthesia with K-F mixture characterized by slow and rough induction (29.16±1.53 sec), poor to moderate muscle relaxation and relatively shorter duration of anesthesia (18.83 ± 3.11 min)with narcosis for about(30.83 ± 5.23 min). The reflexes did not abolish completely especially eye reflexes (corneal and palpebral) and the eyes remained open. H.R. was increased but R.R. was decreased. Recovery was long and rough (78.33 ± 4.77 min) and stand time for (47.50±3.09 min).In conclusion, (P-F) mixtures produce excellent induction of general anesthesia rather than (K-F) in dogs and up to know this is the first report on the uses of these mixtures for induction of anesthesia in dogs.
23
Hadžimešić, Munevera, Semir Imamović, Mirsad Hodžić, Vasvija Uljić, Dželil Korkut, Fatima Iljazagić Halilović, Lejla Selimović Čeke, and Aida Pojskić. "Post anesthesia recovery rate evaluated by using White fast tracking scoring system." Journal of Health Sciences 3, no. 3 (December 15, 2013): 190–95. http://dx.doi.org/10.17532/jhsci.2013.106.
Full textAbstract:
Introduction: Postponed recuperation from anesthesia can lead to different complications such as apnoea, aspiration of gastric content whit consequent development of aspiration pneumonia, laryngospasm, bradycardia, and hypoxia. Aim of this research was to determine infl uence of propofol, sevoflurane and isoflurane anesthesia on post anesthesia recovery rate.Methods: This was a prospective study; it included 90 patients hospitalized in period form October 2011 to may 2012 year, all patients included in the study underwent lumbar microdiscectomy surgery. Patients were randomly allocated to one of three groups: group 1: propofol maintained anesthesia, group 2: sevoflurane and group 3: isofl urane maintained anesthesia. Assessments of recovery rate were done 1, 5 and 10 minutes post extubation using White fast tracking scoring system.Results: Significant difference was observed only 1 minute after extubation (p=0,025) finding recovery rate to be superior in propofol group. Propofol group compared to inhaled anesthesia with sevoflurane group, shows significantly faster recovery from anesthesia only one minute after extubation (p=0,046). In comparison of propofol group and isofl urane anesthesia group, statistical significance was noticed one minute following extubation (p=0,008). Comparison of propofol group and inhaled anesthesia groups recovery rates were not significantly different at all times measured. When we were comparing sevoflurane and isoflurane anesthesia, recovery rates shoved no signifi cant statistical difference.Conclusions: Recovery rate evaluated by using White fast tracking scoring system was superior and with fewer complications in propofol maintained in comparison to sevoflurane and isoflurane maintained anesthesia only one minute post extubation, while after fifth and tenth minute difference was lost.
24
Haque, Md Mahfuzul, and Nasrin Sultana Lucky. "Effects of atrophine sulphate, xylazine hydrochloride, ketamine hydrochloride and diazepam in cats." Research in Agriculture Livestock and Fisheries 6, no. 1 (May 14, 2019): 127–32. http://dx.doi.org/10.3329/ralf.v6i1.41394.
Full textAbstract:
In this experiment eighteen (18) apparently healthy female cats were assigned in three anesthetic groups to attain the objectives of assess the efficacy and adverse effects of anesthetic agents. The body weight of the cats ranged from 2.5 to 3 kg and 8 to 12 months of age. There were divided into following three groups; A: atropine sulphate (0.04 mg/kg), xylazine hydrochloride (1 mg/kg) and Ketamine hydrochloride (5 mg/kg) body weight intramuscularly, B: xylazine hydrochloride (1 mg/kg) and ketamine hydrochloride (5 mg/kg) body weight intramuscularly and C: ketamine hydrochloride (5 mg/kg) and diazepam (1.4 mg/kg) body weight intramuscularly. The mean of induction period was significantly (P<0.05) shorter in Group A and B. Duration of anesthesia, time to first movement there was no difference among these three groups. The induction period was 2.67±0.82, 3.17±0.75 and 13±2.28, Duration of anesthesia was 34.17±2.40, 39.33±1.75 and 35.33±2.73, Time to first movement was 7.5±1.52, 6.67±1.03 and 7±0.894, Time to sternal position was 10.67±1.21, 10.33±1.03 and 19.83±2.07, Time to standing position was 14.67±2.07, 14.33±1.51 and 26.22±2.61 respectively in case of Group A, Group B and C. The induction, duration and recovery period from anesthesia was smooth in atropine sulphate-xylazine-ketamine hydrochloride combination. Salivation was found in xylazine-ketamine hydrochloride combination. Vomition observed onset of action and salivation during recovery period in Ketamine hydrochloride-Diazepam combination. From this study it was found that atropine sulphate-xylazine-ketamine hydrochloride does not show any adverse effect on cat and is an identical satisfactory anesthetic combination which will be helpful for performing any surgical interventions for cats.
Res. Agric., Livest. Fish.6(1): 127-132, April 2019
25
do Nascimento, Paulo, Norma Sueli Pinheiro Módolo, José Fernando do Amaral Meletti, and José Reinaldo Cerqueira Braz. "Sympathetic Hyperactivity, Respiratory Failure, Pruritus, and Anesthesia After Unintentional Epidural Injection of Potassium Chloride: Case Report." Regional Anesthesia & Pain Medicine 23, no. 2 (March 1998): 219–22. http://dx.doi.org/10.1136/rapm-00115550-199823020-00019.
Full textAbstract:
Background and ObjectivesA combination of epidural and general anesthesia has been widely used to attenuate the surgical stress response and to provide postoperative analgesia. This case report illustrates the use of this anesthetic technique. Analgesia was induced with local anesthetic in the immediate postoperative period using unintentional 19.1% potassium chloride (KCI) as diluent.MethodsAn ASA I male patient was scheduled for surgical correction of idiopathic megaesophagus under continuous epidural anesthesia combined with general anesthesia. In the postoperative period, while preparing 10 mL 0.125% bupivacaine to be administered through the epidural catheter for pain control, 5 mL 19.1% KCI was unintentionally used as diluent, resulting in a 9.55% potassium solution concentration.ResultsThe patient developed warmness of the lower limbs, tachycardia, hypertension, intense pruritus on the chest, agitation, exacerbation of sensory and motor blocks, and respiratory failure secondary to pulmonary edema, requiring ventilatory support. Total recovery was observed after 24 hours.ConclusionsEpidurally injected potassium leads to severe clinical manifestations caused by autonomic dysfunction, spinal cord irritation, and possible release of histamine. Despite continuous recommendations, ampule misidentification still happens in hospitals, frequently leading to serious accidents.
26
Song, Dajun, Girish P. Joshi, and Paul F. White. "Titration of Volatile Anesthetics Using Bispectral Index Facilitates Recovery after Ambulatory Anesthesia." Anesthesiology 87, no. 4 (October 1, 1997): 842–48. http://dx.doi.org/10.1097/00000542-199710000-00018.
Full textAbstract:
Background The bispectral (BIS) index has previously been shown to be a quantifiable measure of the sedative and hypnotic effects of anesthetic drugs. This study was designed to assess the effect of BIS monitoring on the utilization of volatile anesthetics and their recovery profiles after ambulatory surgery. Methods Sixty consenting women undergoing outpatient laparoscopic tubal ligation procedures were randomly assigned to one of four treatment groups. After a standardized induction, anesthesia was maintained with either desflurane (Groups I and II) or sevoflurane (Groups III and IV) in combination with nitrous oxide, 65%, and fentanyl. In the control groups (Groups I and III), the anesthesiologists were blinded to the BIS value, and the volatile anesthetics were administered according to standard clinical practice. In Groups II and IV, the volatile anesthetics were titrated to maintain the BIS value at 60. The volatile anesthetic usage and the times from discontinuation of anesthesia to verbal response, orientation, and home-readiness were recorded. Results During the maintenance period, the BIS values were significantly lower in the control groups (mean, 42) compared with the BIS-titrated groups (mean, 60). The volatile anesthetic usage in the BIS-titrated groups was 30-38% lower (P < 0.05) compared with the control groups. Similarly, the times to verbal responsiveness were 30-55% shorter in the BIS-titrated (vs. control) groups. Conclusions Titrating desflurane and sevoflurane using the BIS monitor decreased their utilization and contributed to a faster emergence from anesthesia in outpatients undergoing laparoscopic tubal ligation procedures.
27
Baki, Md Abdullah-Hel, Kawser Ahmed, Rizowana Akter, Nirmal Kumar Barman, Md Monwar Hossein, Ashutosh Dev Sharma, and Shiladitya Shil. "Comparison of Sevoflurane and Halothane Anesthesia Cognitive Function in Adult." Global Academic Journal of Medical Sciences 5, no. 03 (June 21, 2023): 156–61. http://dx.doi.org/10.36348/gajms.2023.v05i03.006.
Full textAbstract:
Background: Patients reach their full cognitive and psychomotor potential during the intermediate period of recovery. We still utilize Halothane, which has a delayed recovery profile, despite the fact that rapid clearance drugs like Sevoflurane have a positive impact on early cognitive recovery, which permits early mobility and reduces post-surgical complications. Objective: The study's goal was to promote the use of sevoflurane over halothane by contrasting the two anesthetics' effects on patients' cognitive functioning after surgery. Method: The prospective randomized comparative study was carried out in the Department of Anaesthesia, Analgesia and Intensive Care Medicine, between the period of September 2021 to June 2022. Study population was the patients of either sex, aged between18-50 years, ASA-I and II, patients undergoing elective surgery by general anaesthesia, lasting for 1 hour or more and remaining 24 hours after surgery. A total number of 100 patients were divided into two groups. 50 patients were in Sevoflurane group and 50 in Halothane group. Results: Group- Sevoflurane had a considerably faster emergence time (10.85 min vs. 15.13 min, P0.001) than Group- Halothane. Group- Sevoflurane had a mean BAMSE score of 29 at baseline and showed no change by the conclusion of the observation period, but Group- Halothane saw their scores both drop and then recover. Patients in Group- Sevoflurane finished the (TMT-A) 30 minutes after regaining consciousness in a considerably shorter amount of time (40. 9 seconds vs. 55. 8 seconds, P 0.001). Furthermore, there was no statistically significant difference between the groups after 1.5 hours, 2.5 hours, or 3.5 hours. Conclusion: So the study concludes that adult patient of sevoflurane group experienced an early post-operative cognitive recovery than halothane group. Though sevoflurane is costly, considering the benefits of patients in terms of early cognitive recovery that causes less postoperative complications and shorter hospital stay, sevoflurane should be used instead of halothane.
28
Abougabal, Ayman, Engy Hamed, Asser Mannaa, Nashwa Nabil, and Mahmoud Badry. "Efficacy of ultrasound guided rectus sheath block on the postoperative quality of recovery in laparotomy surgeries; a randomized control trial." Anaesthesia, Pain & Intensive Care 28, no. 3 (May 12, 2024): 489–94. http://dx.doi.org/10.35975/apic.v28i3.2456.
Full textAbstract:
Background: Recovery after surgery and anesthesia is a complex process therefore a variety of measurement tools have been developed such as QoR-40 and QoR-15 questionnaires to assess quality of recovery. We assessed the opioid sparing effect of rectus sheath (RS) blocks in improving the quality of recovery following midline laparotomy surgeries. Methodology: A randomized, controlled, open-labelled trial was conducted in the General surgery unit. Adult patients scheduled for elective midline laparotomy surgery under general anesthesia were included. Patients were divided into two groups: LA group and control group. Patients in the LA group received ultrasound guided, bilateral rectus sheath block, while patients in the control group received patient-controlled analgesia for postoperative control. Results: Fifty-two patients were screened for eligibility. Median (range) aggregated global QoR-15 scores at 24 h were significantly greater in the LA group, indicating good quality of recovery compared with the control group; 107 (101-112) vs. 72 (68-74) with P < 0.001. In addition, pain profile was better in the LA group as 10 out of 24 (41%) Patients in the LA group required additional boluses of morphine during the 24-h period compared to 100% of patients in the control group (P < 0.001). Conclusion: Ultrasound guided rectus sheath block provides better quality of recovery profile in midline laparotomy compared to opioids. Abbreviations: ERAS - Enhanced Recovery After Surgery; LA - Local Anesthetic; RS - Rectus Sheath; RSB - Rectus Sheath Block; US - Ultrasound; QoR-15 - Quality of Recovery-15 Questionnaire; QoR-40 - Quality of Recovery-40 Questionnaire. Preregistration: The trial was registered on ClinicalTrials.gov (NCT05244746) after obtaining Ethical committee approval at Kasr AlAiny Cairo University (code:MS-202-2021). Keywords: Anesthesia Recovery Period; laparotomy; Nerve Block. Citation: Abougabal A, Hamed E, Mannaa A, Nabil N, Badry M. Efficacy of ultrasound guided rectus sheath block on the postoperative quality of recovery in laparotomy surgeries; a randomized control trial. Anaesth. pain intensive care 2024;28(3):489−494; DOI: 10.35975/apic.v28i3.2456 Received: May 12, 2023; Reviewed: January 17, 2024; Accepted: March 15, 2024
29
Hassan, Bakhan Rafiq, Nasreen Muhialddin Abdulrahman, Vian Muhammed Ahmad, and Shagul Jalal Mohammed. "Effect of fish weights and clove powder levels on anesthesia and recovery time in common carp Cyprinus carpio L." Tikrit journal for agricultural sciences 21, no. 2 (June 30, 2021): 14–22. http://dx.doi.org/10.25130/tjas.21.2.3.
Full textAbstract:
This study aimed to demonstrate how different fish weights and clove powder concentration levels together influence anesthesia and recovery time in Cyprinus carpio. Two different body weights classes of common carp (45±5g and 95±5g) were subjected to three concentrations of clove powder (200, 300 and 400mg/L) each replicated four times. At each treatment combination, the anesthetic induction and recovery times were recorded, fish held for a period of one week to two months following the experiments to assess short-term and long-term mortality. Significant differences (P<0.05) appeared in the effect of combination between the different levels of clove powder (mg/L) with the two different weight common carp (C. carpio L.) on anesthesia time, but there was no difference in recovery time between the two size groups. The induction time was less than one minute for doses of 300 and 400 mg/L in lower fish weight 45±5g while in 200mg/L dose with 95±5g of fish weight it needed more than 9 minutes. At all tested concentrations, induction time was significantly weight-dependent (p< 0.05), but the recovery time was not. Significant alterations were recorded in the hematological variables of the fish (RBC, HB, MCH and WBC), no mortality was observed. This study has demonstrated that clove powder can be safely and effectively use in the anesthesia of common carp and anesthesia time affect by doses of clove powder with fish weight.
30
Tantri, Aida Rosita, Juan Carson Roy Nathanael Marbun, and Aldy Heriwardito. "A randomized controlled trial comparing the recovery time after spinal anesthesia with 2% hyperbaric prilocaine 50 mg vs. 0.5% hyperbaric bupivacaine 12.5 mg for cystoscopic procedures." Anaesthesia, Pain & Intensive Care 27, no. 6 (December 12, 2023): 689–96. http://dx.doi.org/10.35975/apic.v27i6.2145.
Full textAbstract:
Background: Cystoscopy is a urologic procedure performed as a diagnostic or a therapeutic intervention, usually requiring spinal anesthesia (SA). Bupivacaine is a frequently used spinal anesthesia agent. However, the prolonged duration of its effect is a disadvantage. Prilocaine may be an alternative for spinal anesthesia in cystoscopy, which has a shorter duration of action compared to bupivacaine. We compared recovery time of 2% hyperbaric prilocaine 50 mg vs. 0.5% hyperbaric bupivacaine 12.5 mg for cystoscopic procedures under spinal anesthesia.
Methods: This study was a randomized controlled trial involving 66 patients who underwent cystoscopy in Dr. Cipto Mangunkusumo National General Hospital under SA. Subjects were randomized into two groups, i.e. prilocaine group to receive SA with hyperbaric prilocaine 2% 50 mg + fentanyl 25 µg and bupivacaine group to receive hyperbaric bupivacaine 0.5% 12.5 mg + fentanyl 25 µg. Following SA, the time to lift the leg 45 degrees and time to regain the ability to walking unsupported were noted in both groups and statistically compared. Hemodynamic changes in SpO2 and NIBP at fixed periods, as well as adverse effects were recorded.
Results: Hemodynamic changes and adverse effects were comparable between the two groups. The mean time to lift a leg 45 degrees (93.88 min vs. 180.36 min; P < 0.001) and the time until the patient walked (144.91 min vs. 259.76 min; P < 0.002) were significantly short in the prilocaine group. The mean regression time for prilocaine and bupivacaine SA was 69.36 ± 35.85 and 131.88 ± 79.43 min respectively; the difference being significant (P < 0.001).
Conclusion: Hyperbaric prilocaine 2% has a shorter recovery period when compared to hyperbaric bupivacaine 0.5% for spinal anesthesia and is appropriate for the length of the cystoscopy, making it a viable spinal anesthetic option.
Keywords: Bupivacaine; Cystoscopy; Prilocaine; Anesthesia, Spinal; Recovery Time
Citation: Tantri AR, Marbun JCRN, Heriwardito A. A randomized controlled trial comparing the recovery time after spinal anesthesia with 2% hyperbaric prilocaine 50 mg vs. 0.5% hyperbaric bupivacaine 12.5 mg for cystoscopic procedures. Anaesth. pain intensive care 2023;27(6):689−696; DOI: 10.35975/apic.v27i6.2145
Received: January 29, 2023; Reviewed: October 23, 2023; Accepted: October 23, 2023
31
Sandhya, A., R. Mamatha, and Antara Banerjee. "Postoperative Nausea and Vomiting in Day Care Patients: A Comparative Randomized Controlled Trial of Total Intravenous Anesthesia with Propofol, Air, and Oxygen vs Inhalation Anesthesia with Isoflurane and Nitrous Oxide." Journal of Medical Sciences 1, no. 4 (2015): 63–68. http://dx.doi.org/10.5005/jp-journals-10045-0019.
Full textAbstract:
ABSTRACT Introduction We compared the incidence of postoperative nausea and vomiting (PONV) after total intravenous anesthesia (TIVA) using propofol–air to inhalational anesthesia with isoflurane–nitrous oxide in day care patients at a tertiary care academic institution. Materials and methods We randomized 60 patients and assigned to either group I (inhalational anesthesia with isoflurane– nitrous oxide) or group II (TIVA with propofol–air). Incidence of PONV, use of anti-emetics, and duration of stay in the recovery were recorded for 72 hours by blinded observers. Results Total intravenous anesthesia reduced the PONV up to 72 hours by 27% among our patients (from 37 to 10%, p < 0.001). This effect was seen more in the early postoperative period. Overall, 13.3% of patients in the group I received antiemetic compared to 40% in group II. In our study, patients without PONV were discharged from the recovery room 15 minutes earlier after TIVA than after isoflurane and N2O anesthesia. Conclusion Total intravenous anesthesia with propofol and air resulted in a reduction of PONV compared with iso-flurane–nitrous oxide anesthesia. Overall, patients in group I required less rescue antiemetic, compared to group II. Total intravenous anesthesia resulted in shorter stay in the postoperative anesthetic care unit compared to isoflurane–N2O group. How to cite this article Sandhya A, Mamatha R, Banerjee A, Sahajananda H. Postoperative Nausea and Vomiting in Day Care Patients: A Comparative Randomized Controlled Trial of Total Intravenous Anesthesia with Propofol, Air, and Oxygen vs Inhalation Anesthesia with Isoflurane and Nitrous Oxide. J Med Sci 2015;1(4):63-68.
32
Pain, L., P. Oberling, G. Sandner, and G. Di Scala. "Effect of Propofol on Affective State as Assessed by Place Conditioning Paradigm in Rats." Anesthesiology 85, no. 1 (July 1, 1996): 121–28. http://dx.doi.org/10.1097/00000542-199607000-00017.
Full textAbstract:
Background Whether propofol produces a pleasant affective state remains unclear from clinical studies. In the current study, the effect on affective state of subanesthetic and anesthetic doses of propofol was assessed at a preclinical level with rats in a place conditioning paradigm. Propofol was compared with methohexital. Methods In the place conditioning paradigm, propofol-induced effect was repeatedly paired with one of two distinguishable compartments of the apparatus, whereas the vehicle-induced effect was repeatedly paired with the other compartment. During a subsequent free-choice test, a preference for the drug-paired compartment over the vehicle-paired compartment would be indicative of pleasant state induced by the drug. For all experiments, the conditioning session lasted 8 days and consisted of four pairings of the drug with one compartment and four pairings of the equivalent volume of vehicle with the other compartment. In experiment 1A, four groups of rats were designated according to the dose of propofol that they received intraperitoneally: 0,30,60, or 90 mg/kg. In experiment 1B, the same procedure was used with subanesthetic doses of intraperitoneal methohexital: 0,10,20, or 30 mg/kg. In experiment 2, the rats were conditioned during the recovery period from short-term anesthesia. For one group, anesthesia was induced by propofol (100 mg/kg) whereas for the other group, anesthesia was induced by an equivalent anesthetic dose of methohexital (40 mg/kg). Results In experiment 1A, the 30-mg/kg, 60-mg/kg, and 90-mg/kg groups showed a place preference for the drug-paired compartment, but only the group conditioned with 60 mg/kg propofol significantly differed from the 0-mg/kg group. In experiment 1B, the groups conditioned with methohexital showed no place preference for the drug-paired compartment. In experiment 2, the rats showed a place preference for the compartment in which they recovered from propofol-induced anesthesia but no place preference for the compartment in which they recovered from methohexital-induced anesthesia. Conclusions Propofol, but not methohexital, induced a pleasant affective state in rats at subanesthetic doses as well as during recovery from an anesthetic dose.
33
Santos, Djair Teixeira, Veronika Wittmann, Victoria Arrifano Moraes, Debora Koffke Alves, Kleber Peixoto da Cunha Junior, Leoni Bonamin, Fabiana Rodrigues Santana, Daniele Di Marco, and Cideli de Paula Coelho. "Role of high dilutions in anesthetic recovery in dogs." International Journal of High Dilution Research - ISSN 1982-6206 14, no. 2 (August 27, 2021): 51. http://dx.doi.org/10.51910/ijhdr.v14i2.795.
Full textAbstract:
Introduction: Post-operative period has been associated with risks like depression of cardiorespiratory system, hypothermia etc., especially under influence of anesthesia. Therefore, short anesthetic recovery in important.
Aims: The objective of this study was to evaluate whether homeopathic drug Papaver somniferum 30cH can help reducing the duration of post-surgery anesthesia, and whether there is any change in cardiac rhythm and body temperature.
Materials and Methods: We evaluated 16 dogs submitted for sterilization surgery in the Veterinary Hospital of University of Santo Amaro. The animals were divided in three groups: Group-I: treated with Papaver 30cH (n=7); Group-II: treated with 10% hydroalcoholic solution (n=5) (positive control); and Group-III: negative controls (who did not take anything)(n=4). Four drops of drug/placebo were given per os, immediately after the surgery, repeated every 15 min until dog became conscious. Data were analyzed statistically by ANOVA followed by the Tuckey Krammer Test, p ≤0.05 being significant.
Results: The results showed that animals treated with Papaver returned from anesthesia (20 ± 2.80 minutes) faster than the hydroalcoholic group (34±6.49 minutes), p≤0.05. No statistical difference was seen between the positive and negative control. There was no statistical difference between the groups in cardiorespiratory and temperature parameters.
Discussion: Other studies have shown similar effects using Veratrum album. The Papaver somniferum has remarkable pharmacological action in bradycardia, bradypnea, respiratory smooth muscle, with sedative and analgesic properties.
Conclusion: The Papaver somniferum 30cH may be considered as a medicinal aid in the shortening the post-surgical anesthesia time, however more studies are needed to establish this observation.
34
Zu, Baoli, Yong Yang, and Shengchi Shi. "Effects of Different Doses of Dexmedetomidine Combined with Thoracic Paravertebral Nerve Block Anesthesia on Agitation and Hemodynamics in Patients Undergoing Thoracotomy during Recovery." Evidence-Based Complementary and Alternative Medicine 2022 (June 29, 2022): 1–5. http://dx.doi.org/10.1155/2022/7804584.
Full textAbstract:
Objective. To investigate the effect of different doses of dexmedetomidine combined with thoracic paravertebral nerve block anesthesia on agitation and hemodynamics in patients undergoing thoracotomy during recovery. Methods. One hundred patients who underwent thoracotomy in our hospital from August 2018 to April 2021 were enrolled and assigned (1 : 1 : 1 : 1) into 4 groups via the random number table method. The patients in the control group were treated with double-lumen tube general anesthesia + ropivacaine for thoracic paravertebral nerve block anesthesia; patients in experimental group A received double-lumen general anesthesia +0.5 μg·kg−1 dexmedetomidine + ropivacaine for thoracic paravertebral nerve block anesthesia; patients in experimental group B received thoracic paravertebral nerve block anesthesia with double-lumen general anesthesia +1.0 μg·kg−1 dexmedetomidine + ropivacaine; patients in experimental group C received thoracic paravertebral nerve block anesthesia with double-lumen general anesthesia +1.5 μg·kg−1 dexmedetomidine + ropivacaine. The postoperative recovery time and visual analog scale (VAS), level of hemodynamics (heart rate (HR), mean arterial pressure (MAP)), agitation during the recovery period, and complications were compared amongst the 4 groups of patients at different time points. Results. The postoperative VAS scores of patients in groups B2 and B3 were slightly lower than those of patients in groups A and B1, but a one-way analysis of variance revealed no statistical difference in the postoperative recovery time and VAS pain scores of the four groups ( P > 0.05 ), and the recovery time of patients in experimental group C was slightly higher than that of patients in group B2. At T0 and T1, there was no significant difference in the levels of HR and MAP among the four groups ( P > 0.05 ). The levels of HR and MAP of the patients in groups B2 and B3 were significantly different from the patients in the control group and experimental group A at T2 and T3 ( P < 0.05 ). The patients in experimental group B and experimental group C showed better outcomes than those in the control group and experimental group A in the assessment of agitation during the recovery period ( P < 0.05 ). There was no significant difference in the incidence of complications among the four groups ( P > 0.05 ). Conclusion. In line with the principle of preference for a small anesthesia dose, 1.0 μg·kg−1 dose of dexmedetomidine combined with ropivacaine produces a pronounced efficacy in patients undergoing thoracotomy. It effectively controls the occurrence of agitation during the recovery period and maintains the stability of the patient’s hemodynamics, with a high clinical safety profile.
35
LIANG, YUE, ZHENGRU WANG, LIUYANG LI, JIPENG LI, XINWU MA, SHULIN CHEN, YUPENG YIN, and DEZHANG LU. "Comparison of the anesthesia effects of ketamine, dexmedetomidine and tiletamine-zolazepam with or without tramadol in cats." Medycyna Weterynaryjna 77, no. 09 (2021): 6555–2021. http://dx.doi.org/10.21521/mw.6555.
Full textAbstract:
This study investigated the analgesia effects of intramuscular injection of ketamine, dexmedetomidine and tiletamine-zolazepam combined with tramadol (KDZT) and compared the efficacy of this combination with that of ketamine, dexmedetomidine and tiletamine-zolazepam (KDZ) in Chinese local mongrel cats. Ten cats were tested twice as a comparison between the two groups, and the interval between the two groups was more than a week. The animals received ketamine (10 mg/kg), dexmedetomidine (10 μg/kg) and zoletil (5 mg/kg) combined with or without tramadol (2 mg/kg) for anesthesia in separate tests. Heart rate, respiration rate, non-invasive systolic pressure, hemoglobin oxygen saturation, rectal temperature, subjective pain scores and venous blood-gas were measured simultaneously. The induction time, recovery time of the righting reflex, standing and walking, the time during the anesthesia period were recorded. Cardiopulmonary variables changed after injection, some of which were significantly different from baselines before anesthesia induction. Values regarding blood gas changed after intramuscular administration, and significant differences were found between two groups at one of the timepoints. Both KDZT and KDZ provided adequate analgesia in cats. The induction period of two anesthetic mixtures was within 1-3 min and could effectively maintain anesthesia for 75-175 min. The change of physiological parameters remained within a biologically acceptable range and was not significantly different between the two groups. The use of KDZT resulted in better anesthesia, with shorter anesthesia induction period and longer anesthesia period compared with KDZ. No side effects were observed, no rescue analgesic was required.
36
Chan, Vincent W. S., Mitchell J. Weisbrod, Zsuzsanna Kaszas, and Camelia Dragomir. "Comparison of Ropivacaine and Lidocaine for Intravenous Regional Anesthesia in Volunteers." Anesthesiology 90, no. 6 (June 1, 1999): 1602–8. http://dx.doi.org/10.1097/00000542-199906000-00016.
Full textAbstract:
Background Ropivacaine may be useful for intravenous regional anesthesia, but its anesthetic effectiveness and toxicity have not been evaluated. Methods Two doses of ropivacaine (1.2 and 1.8 mg/kg) and one dose of lidocaine (3 mg/kg) were compared for intravenous regional anesthesia in 15 volunteers. An arm tourniquet was inflated for 30 min after injection and then deflated in two cycles. Sensory block was measured by response to touch, cold, pinprick, and transcutaneous electric stimulation, and motor function was measured by hand grip strength and muscle power. Median, ulnar, radial, and musculocutaneous nerve functions were tested before local anesthetic injection and then at 5-min intervals until blocks resolved. The plasma ropivacaine and lidocaine concentrations were determined from arterial and venous blood samples drawn from the unanesthetized arm. Results Sensory and motor blocks were complete within 25 min and 30 min, respectively, in all three treatment groups. However, recovery of sensory and motor block after tourniquet release was slowest in the high-dose ropivacaine group. Anesthesia to pinprick and transcutaneous electric stimulation was sustained in all the volunteers in the high-dose ropivacaine group for 55 min and 85 min, respectively, whereas complete recovery was observed in the lidocaine group (P = 0.008) and partial recovery in the low-dose ropivacaine group (P < 0.05) during the same period. Motor block also was sustained in the high-dose ropivacaine group for 70 min, which was significantly longer than in the lidocaine group (P < 0.05). All volunteers (five of five) given lidocaine and one volunteer given high-dose ropivacaine reported light-headedness and hearing disturbance during tourniquet release when the arterial plasma lidocaine and ropivacaine concentrations were 4.7+/-2.1 microg/ml (mean) and 2.7 micro/ml, respectively. Conclusion Compared with lidocaine, intravenous regional anesthesia with ropivacaine appears to be comparable but has longer-lasting residual anesthesia.
37
Plourde, Gilles, Pascal Belin, Daniel Chartrand, Pierre Fiset, Steven B. Backman, Guoming Xie, and Robert J. Zatorre. "Cortical Processing of Complex Auditory Stimuli during Alterations of Consciousness with the General Anesthetic Propofol." Anesthesiology 104, no. 3 (March 1, 2006): 448–57. http://dx.doi.org/10.1097/00000542-200603000-00011.
Full textAbstract:
Background The extent to which complex auditory stimuli are processed and differentiated during general anesthesia is unknown. The authors used blood oxygenation level-dependent functional magnetic resonance imaging to examine the processing words (10 per period; compared with scrambled words) and nonspeech human vocal sounds (10 per period; compared with environmental sounds) during propofol anesthesia. Methods Seven healthy subjects were tested. Propofol was given by a computer-controlled pump to obtain stable plasma concentrations. Data were acquired during awake baseline, sedation (propofol concentration in arterial plasma: 0.64 +/- 0.13 microg/ml; mean +/- SD), general anesthesia (4.62 +/- 0.57 microg/ml), and recovery. Subjects were asked to memorize the words. Results During all periods including anesthesia, the sounds conditions combined elicited significantly greater activations than silence bilaterally in primary auditory cortices (Heschl gyrus) and adjacent regions within the planum temporale. During sedation and anesthesia, however, the magnitude of the activations was reduced by 40-50% (P < 0.05). Furthermore, anesthesia abolished voice-specific activations seen bilaterally in the superior temporal sulcus during the other periods as well as word-specific activations bilaterally in the Heschl gyrus, planum temporale, and superior temporal gyrus. However, scrambled words paradoxically elicited significantly more activation than normal words bilaterally in planum temporale during anesthesia. Recognition the next day occurred only for words presented during baseline plus recovery and was correlated (P < 0.01) with activity in right and left planum temporale. Conclusions The authors conclude that during anesthesia, the primary and association auditory cortices remain responsive to complex auditory stimuli, but in a nonspecific way such that the ability for higher-level analysis is lost.
38
Eidan, Anthony, Angela Ratsch, Elizabeth A. Burmeister, and Geraldine Griffiths. "Comparison of Opioid-Free Anesthesia Versus Opioid-Containing Anesthesia for Elective Laparoscopic Surgery (COFA: LAP): A Protocol Measuring Recovery Outcomes." Methods and Protocols 3, no. 3 (August 13, 2020): 58. http://dx.doi.org/10.3390/mps3030058.
Full textAbstract:
The administration of opioids is a central element in contemporary anesthetic techniques in Australia; however, opioids have a range of side effects. As an alternative, opioid-free anesthesia (OFA) is an emerging mode of anesthesia intended to avoid these side effects. This study is the first to publish the use of OFA in Australia and is conducted in a regional Queensland Health Service. The design will utilize a randomized clinical trial (RCT) to investigate the impact of OFA for patients having an elective laparoscopic cholecystectomy (n = 40) or tubal ligation (n = 40). Participant outcomes to be measured include: Quality of Recovery (QoR-15); Oral Morphine Equivalent Daily Dose (OMEDD) at 24-h post-operatively; time to first opioid (TTFO) dose; post-operative nausea and vomiting (PONV); Post Anesthetic Care Unit length of stay (PACU-LOS); and hospital length of stay (LOS). The findings may challenge the essentiality of opioids in the peri-operative period, which in turn would influence the future intra-operative management of surgical patients. Ultimately, a reduction in anesthesia-associated opioid use will support a more general decline in opioid use.
39
Leite, Gisele Martins de Paula, Luís Eugênio Franklin Augusto, Vanessa Guedes Pereira, Adriano França Cunha, Kelly Cristine de Sousa Pontes, and Jader Lúcio Pinheiro Santana. "Comparative study of epidural anesthesia in dogs by weight or occipito-coccygeal distance." Revista Ceres 64, no. 1 (February 2017): 12–17. http://dx.doi.org/10.1590/0034-737x201764010002.
Full textAbstract:
ABSTRACT The effects of volume on lumbosacral epidural block in dogs were evaluated using two different doses of 2% lidocaine. Ten adult dogs, without defined breed, were subjected to two different anesthetic protocols. In the first, the local anesthetic was calculated based on the body weight (GP), wherein 1.0 mL of local anesthetic was used for each 3.5 kg; in the second protocol, the dose was stipulated according to the occipito-coccygeal (DG) distance with 1.5mL of local anesthetic for every 10 cm of distance. The available time, recovery period, extent of block, and rectal temperature were measured. After the analysis of the results, it was possible to verify that there was an increase in the time in GD when compared with GP, due to the greater volume administered in that group. The recovery period remained similar in both groups, despite the use of different doses. Regarding the extent of blockade, there was an increase in GD in relation to GP due to the increase of the local anesthetic dose. On the other hand, the rectal temperature presented a difference between the groups, remaining lower and below the reference values for the species in GD compared with GP at all moments analyzed, possibly due to a sympathetic action triggered by the cranial extension of the epidural block. It could be concluded that when a longer time and a more cranial blockade of epidural anesthesia are desired, the anesthesia volume should be based on the occipito-coccygeal distance, however, observing the rectal temperature.
40
Srinivasan, Ilavajady, Samuel Strantzas, and Mark W. Crawford. "Phasic Genioglossus and Palatoglossus Muscle Activity during Recovery from Sevoflurane Anesthesia." Anesthesiology 119, no. 3 (September 1, 2013): 562–68. http://dx.doi.org/10.1097/aln.0b013e318295a27b.
Full textAbstract:
Abstract Background: Inhalational anesthetic effects on upper airway muscle activity in children are largely unknown. The authors tested the hypothesis that phasic inspiratory genioglossus and palatoglossus activity increases during recovery from sevoflurane anesthesia in a dose-dependent manner in children. Methods: Sixteen children, aged 2.0 to 6.9 yr, scheduled for elective urological surgery were studied. Electromyogram recordings were acquired using intramuscular needle electrodes during spontaneous ventilation. After a 15-min period of equilibration, electromyogram activity was recorded over 30 s at each of three end-tidal concentrations, 1.5, 1.0, and 0.5 minimum alveolar concentration (MAC), administered in sequence. Results: Phasic genioglossus activity was noted in four children at 1.5 MAC, five at 1.0 MAC, and six children at 0.5 MAC sevoflurane. Phasic palatoglossus activity was noted in 4 children at 1.5 MAC, 6 at 1.0 MAC, and 10 children at 0.5 MAC sevoflurane. Both the proportion of children exhibiting phasic activity, and the magnitude of phasic activity increased during recovery from anesthesia. For the genioglossus, decreasing the depth of sevoflurane anesthesia from 1.5 to 1.0 MAC increased phasic activity by approximately 35% and a further decrease to 0.5 MAC more than doubled activity (median [range] at 1.5 and 0.5 MAC: 2.7 μV [0 to 4.0 μV] and 8.6 μV [3.2 to 17.6], respectively; P = 0.029). A similar dose-related increase was recorded at the palatoglossus (P = 0.0002). Conclusions: Genioglossus and palatoglossus activity increases during recovery from sevoflurane anesthesia in a dose-dependent manner over the clinical range of sevoflurane concentrations in children.
41
Kotani, Naoki, Tetsuya Kushikata, Hiroshi Hashimoto, Daniel I. Sessler, Masatoshi Muraoka, and Akitomo Matsuki. "Recovery of Intraoperative Microbicidal and Inflammatory Functions of Alveolar Immune Cells after a Tobacco Smoke-free Period." Anesthesiology 94, no. 6 (June 1, 2001): 999–1006. http://dx.doi.org/10.1097/00000542-200106000-00013.
Full textAbstract:
Background Tobacco smoking inhibits alveolar macrophage function, but cessation of smoking markedly reduces the risk of postoperative pulmonary complications. The authors therefore evaluated the effect of nonsmoking duration on both antimicrobial and inflammatory functions of alveolar macrophages during anesthesia and surgery. Methods The authors studied 15 patients who had never smoked, 15 current smokers, and 41 former smokers, all of whom underwent general anesthesia. Former smokers were further allocated to one of three groups depending on their smoke-free periods: 2 months (n = 13), 3-5 months (n = 13), and 6-12 months (n = 15). Alveolar immune cells were collected by bronchoalveolar lavage immediately after induction of anesthesia, at 2 and 4 h after induction of anesthesia, and at the end of surgery. Opsonized and nonopsonized phagocytosis were measured. Microbicidal activity was determined as the ability of the macrophages to kill Listeria monocytogenes directly. Finally, we determined the expression of proinflammatory cytokines, including interleukin 1beta, interleukin 8, interferon gamma, and tumor necrosis factor alpha, and of antiinflammatory cytokines (interleukin 4 and 10) by semiquantitative polymerase chain reaction. Results Nonopsonized and opsonized phagocytosis and microbicidal activity of alveolar macrophages (antimicrobial functions) decreased 20-50%, and the expression of genes for all proinflammatory and antiinflammatory cytokines increased 3-30-fold over time in all groups. Starting 4 h after induction of anesthesia, the decreases in antimicrobial functions were 1.5-3 times greater in current and former smokers (2 months' abstinence) than in patients who had never smoked. Starting 4 h after anesthesia, the increase in expression of all cytokines, except interleukin 8, was twofold to fivefold less in current and former smokers (2-6 months' abstinence) than in patients who had never smoked. Conclusion Our data suggest that former smokers may have a limited ability to mount effective pulmonary immune defenses for long as 6 months after stopping cigarette use.
42
Furumoto, Kayo, Kumi Ogita, Tomomi Kamisaka, Asami Kawasumi, Koushi Takata, Noritaka Maeta, Takamasa Itoi, Masakatsu Nohara, Kaori Saeki, and Teppei Kanda. "Effects of Multimodal Analgesic Protocol, with Buprenorphine and Meloxicam, on Mice Well-Being: A Dose Finding Study." Animals 11, no. 12 (November 30, 2021): 3420. http://dx.doi.org/10.3390/ani11123420.
Full textAbstract:
The anesthetic or analgesic agent of choice, route and frequency of anesthetic or analgesic administration, and stressors induce distress during the perioperative period. We evaluated a multimodal analgesic protocol using buprenorphine and meloxicam on the well-being of mice. Twenty-four Slc:ICR male mice were divided into control, anesthesia + analgesia, and surgery + anesthesia + analgesia groups. Tap water (orally: PO) and water for injection (subcutaneous: SC) were administered to the control group. Buprenorphine was administered twice (SC, 0.1 mg/kg/8 h) and meloxicam was administered thrice (PO, 5 mg/kg/24 h) to the anesthesia + analgesia and surgery + anesthesia + analgesia groups. The mice were subjected to laparotomy and assessed for several parameters. Even in absence of surgical pain, the anesthesia + analgesia group presented the same negative effects as the surgery + anesthesia + analgesia group. This multimodal analgesic protocol for mice was expected to have an analgesic effect on pain associated with laparotomy but was not sufficient to prevent food intake and weight decrease. This does not negate the need to administer analgesics, but suggests the need to focus on and care not only about the approach to relieve pain associated with surgery, but also other types of distresses to minimize negative side effects that may interfere with postoperative recovery in mice.
43
İŞLER, C. T., M. E. ALTUĞ, Z. YURTAL, and M. Z. Y. DEVECI. "Effects of diazepam, ketamine HCl and sevoflurane anesthesia on vital and recovery values of nine long legged buzzards (Buteo rufinus) upon wing amputation." Journal of the Hellenic Veterinary Medical Society 69, no. 3 (October 10, 2018): 1071. http://dx.doi.org/10.12681/jhvms.18877.
Full textAbstract:
In this clinical study, effects of diazepam + ketamine HCl + sevoflurane anesthesia on vital functions and recovery duration and qualityofnine long legged buzzards were evaluated upon wing amputation. Operation was decided for long legged buzzards and heartand breathingrate, body temperature, and reflexes of long legged buzzards were evaluated before, during and after the anesthesia. Diazepam and ketamine HCl injection increased the heart rate whereas it was decreased by sevoflurane. Respiratory rate decreased upon sevoflurane application. Body temperature decreased during anesthesia. Recovery began in the 3rd minute after cessation of sevoflurane administration with return of eye reflexes and completedin the 35th minute. It was observed that although birdsrecovered from anesthesia, danger of hypothermia persisted for a long time.There was a significant difference between the respiratory and heart rates during the ketamine HCl and sevofluraneanesthesia from those in the preoperative period. However, there was no statistically significant difference between pre and post operative periods in terms of vital parameters. For the first time, effects of diazepam + ketamine HCl + sevoflurane anesthesia combination on vital parameters are evaluated in long legged buzzards in Turkey.
44
Fisher, Dennis M., Michael A. E. Ramsay, H. A. Tillmann Hein, Randy J. Marcel, Manohar Sharma, Kirsten J. Ramsay, and Ronald D. Miller. "Pharmacokinetics of Rocuronium during the Three Stages of Liver Transplantation." Anesthesiology 86, no. 6 (June 1, 1997): 1306–16. http://dx.doi.org/10.1097/00000542-199706000-00012.
Full textAbstract:
Background Little is known about the influence of liver transplantation on the pharmacokinetics of most anesthetic drugs. The authors determined the pharmacokinetics of rocuronium during liver transplantation and examined whether variability in pharmacokinetics could explain variability in recovery of neuromuscular function. Methods Twenty patients undergoing liver transplantation were given rocuronium, 600 microg/kg, after induction of anesthesia and again after perfusion of the transplanted liver. Plasma was sampled to determine rocuronium concentrations. Pharmacokinetic models were fit to rocuronium concentrations versus time data using a mixed-effects population approach. Various models permitted changes in clearance (Cl) or central compartment volume to account for changes in hepatic function and circulatory status during the paleohepatic, anhepatic, and neohepatic periods. Time to initial recovery of four twitches of the orbicularis oculi was determined. Results During the paleohepatic and anhepatic periods, the typical value of Cl was 2.47 ml x kg(-1) x min(-1) and was not influenced by the magnitude of preexisting liver disease (as evidenced by prothrombin time, bilirubin, serum albumin, alanine transaminase [ALT], and aspartate transaminase [AST]). During the neohepatic period, the typical value of Cl varied as a function of the duration of warm ischemia of the hepatic allograft and was 2.72 ml x kg(-1) x min(-1) for a patient with an average 60-min period of warm ischemia; time to neuromuscular recovery varied as a function of Cl. Conclusions Despite prolonged hypothermic ischemia, the newly transplanted liver eliminates rocuronium as well as the diseased native liver (and comparably with historical control values). However, some patients had decreased rocuronium Cl during the neohepatic period, apparently a result of prolonged graft warm ischemia. The authors' finding of preservation of hepatic drug elimination in the hepatic allograft is consistent with limited data for other drugs evaluated during anesthesia.
45
Luiza Matos de Lima, Iara, Juliano Biolchi, Juliana Caetano Félix da Silva Mendes, Isadora Scherer Borges, and Juan Carlos Duque Moreno. "Anesthesia of toad (Rhinella icterica) premedicated with dextroketamine and morphine for femur ostheosyntesis." Acta Veterinaria Brasilica 17, no. 3 (January 23, 2024): 24–29. http://dx.doi.org/10.21708/avb.2023.17.3.11507.
Full textAbstract:
In the present work, the objective is to relate the anesthetic procedures performed in a specimen of Rhinella icterica that underwent femoral osteosynthesis, as well as the results obtained regarding anesthetic efficacy and safety, and vital signs measured during the perioperative period. Pre-anesthetic medication was performed with dextroketamine and morphine, from which light anesthesia was obtained. Anesthetic induction was performed in gas chamber with isoflurane to reach surgical anesthetic plane. The animal was monitored by evaluation of anesthetic plane, electrocardiogram, pulse oximetry, counting of gular movements and hart rate by vascular Doppler positioned in the sternum. During the entire perioperative period, care was taken to maintain adequate room temperature and skin moistening, in order to preserve organic functions at physiologic standards for the species. Complete anesthetic recovery occurred quickly compared to previously existing literature. The protocol proved to be effective in promoting general anesthesia and safe in terms of stability of evaluated vital signs, becoming an alternative to the use of tricaine methanesulfonate (MS-222) and eugenol. More study is necessary regarding particular anesthetic effects on each species, and, given the lack of information, it is important to consider physiologic characteristics of amphibians in general to minimize the risks.
46
Hill, Richard S., Peter J. Koltai, and Steven M. Parnes. "Airway Complications from Laryngoscopy and Panendoscopy." Annals of Otology, Rhinology & Laryngology 96, no. 6 (November 1987): 691–94. http://dx.doi.org/10.1177/000348948709600616.
Full textAbstract:
Laryngoscopy and panendoscopy can cause airway complications. To determine the risk to the airway from reintubation following general anesthesia in otolaryngology patients, we examined recovery room and anesthesia records at the Albany Veterans Administration Medical Center covering a 10-year period. From this information we determined the incidence of recovery room reintubation and studied airway risk factors associated with otolaryngologic endoscopy. From 1975 to 1984, 10,060 surgical patients were intubated at the Albany VA Medical Center. Only 17 patients (0.17%) required reintubation. Of 1,365 otolaryngology patients intubated during the same period, 324 had laryngoscopy and 302 had panendoscopy. Significantly, four laryngoscopy patients (1.2%) and nine panendoscopy patients (3%) required recovery room intubation. Nine endoscopy patients needed reintubation within 1 hour of extubation. We conclude that the risk of postoperative airway compromise is significantly greater among patients who underwent diagnostic laryngoscopy and panendoscopy than among patients who had general anesthesia for other reasons.
47
Yakushevsky, A. B., A. N. Plekhanov, and A. B. Ayusheev. "Combined Extended High Spinal Anesthesia and Endotracheal Narcosis: a Clinical Case." Acta Biomedica Scientifica 4, no. 2 (May 25, 2019): 152–54. http://dx.doi.org/10.29413/abs.2019-4.2.23.
Full textAbstract:
Background. In recent years, various methods of combined anesthesia during abdominal surgery have been introduced into clinical practice.Aim. To demonstrate the possibilities of a combination of high prolonged spinal anesthesia and endotracheal anesthesia during abdominal surgery.Materials and methods. A clinical case of combined use of high prolonged spinal anesthesia and endotracheal anesthesia in a 48-year-old patient with a tumor in the right half of the ascending part of the right half of the colon is presented.Results. The patient received a puncture of the spinal space at a standard point and was installed a spinal catheter in the cranial direction for 3 cm. An isobaric solution of marcaine in the initial dose of 20 mg was injected into the catheter. The regulation of the development of the block was regulated by the inclination of the head end of the table by 60°. After that endotracheal anesthesia was performed on the basis of fentanyl and propofol. This combination allowed to expand the scope of surgical intervention, provided adequate pain relief intraoperatively and in the postoperative period, without the use of narcotic analgesics. With the appearance of signs of recovery of pain sensitivity, intraoperatively or in the postoperative period, re-introduction of the anesthetic into the spinal catheter was performed in half of the initial dose with liquor barbotage. In the early postoperative period, the patient was on strict bed rest with a head end of the bed raised at 30–45°. The method provides complete segmental blockade and muscle relaxation in the area of operation, stability of central hemodynamics during surgery and in the postoperative period.Conclusion. This type of anesthesia is more easily tolerated by patients, accompanied by early awakening and extubation, characterized by stability of central hemodynamics, reduced risk of complications, the possibility of prolonging anesthesia with lower doses of narcotic analgesics in the intraoperative period, providing high-quality anesthesia in the postoperative period without resorting to the use of narcotic analgesics.
48
Cho, Ah-Reum. "Enhanced recovery after surgery: anesthesia-related components." Journal of the Korean Medical Association 64, no. 12 (December 10, 2021): 813–19. http://dx.doi.org/10.5124/jkma.2021.64.12.813.
Full textAbstract:
Background: Enhanced recovery after surgery (ERAS) is a multidisciplinary and multimodal evidence-based approach aimed at improving the recovery of surgical patients. Successful implementation of ERAS protocols requires proper perioperative communication and collaboration among surgeons, anesthesiologists, nurses, and other medical personnel.Current Concepts: The anesthesiologist is the clinical leader responsible for the ERAS program. Preoperative patient evaluation, optimization, and patient education are essential components of the ERAS program. The program also involves preoperative fasting and carbohydrate loading to minimize catabolic effects. Selection of an appropriate anesthetic regimen, fluid and temperature management, avoidance of intra/postoperative nausea and vomiting, and multimodal pain management are the key components of ERAS for which the anesthesiologist is responsible.Discussion and Conclusion: Factors that enable the successful implementation of ERAS include the willingness to change to ERAS, formation of multidisciplinary teams to improve cooperation, and support from the hospital management, as well as standardization of order sets and care processes and the appropriate use of audits. As the leader of the ERAS team, the anesthesiologist should be actively involved in comprehensive management of the patient during the perioperative period.
49
Padalko, A. A., D. O. Dziuba, and O. A. Halushko. "Analysis of clinical series with the use of adjuvants to general anesthesia during elective caesarean section." EMERGENCY MEDICINE 19, no. 2 (May 14, 2023): 88–95. http://dx.doi.org/10.22141/2224-0586.19.2.2023.1563.
Full textAbstract:
Background. Caesarean section remains one of the most common surgical interventions in the world. The main disadvantages of the general anesthesia in caesarean section are a high risk of awareness during the operation and a pronounced hemodynamic reaction to the surgical trauma in a patient. The most dangerous period of intervention in terms of these complications is the period before the birth of a child. This article analyzes our own clinical cases of the general anesthesia during elective caesarean section with the addition of adjuvants and compares anesthetic management with world practices. In all cases from our own clinical practice, total intravenous anesthesia with artificial lung ventilation was performed. Intravenous forms of medical drugs were used as adjuvants: paracetamol (1000 mg) and clonidine (100 μg), 30 minutes before the elective surgical intervention. The newborns were examined with the Apgar scale and umbilical venous blood gas analysis was carried out. Preoperative, intraoperative, and postoperative management of patients was based on recommendations of the Enhanced Recovery After Caesarean Section and guidelines of the PROSPECT working group. Results. The analysis of our own clinical cases revealed the presence of a hemodynamic reaction of the patient’s body to the operative injury (in the period before the birth of a child), which does not exceed safe levels; absence of anesthetic complications and cases of accidental awareness during surgery; absence of a negative influence of adjuvants on newborns; sufficient depth of anesthesia and reduction of the intraoperative doses of opioids and intravenous anesthetics (“on patient’s request”). Conclusions. The analysis of clinical cases argues for the need to use “safe adjuvants” (acetaminophen, clonidine) to general anesthesia during elective caesarean section and the necessity for further research.
50
Monzem, Samuel, Paulo Roberto Spiller, Nathalie Bassil Moro Dower, Lianna Ghisi Gomes, Matias Bassinello Stocco, Anderson Soares Castro de Oliveira, Fabiola Niederauer Flôres, and Luciana Dambrósio Guimarães. "Total Intravenous Anesthesia with Propofol Associated with Fentanyl, Lidocaine or Ketamine in Bitches Submitted to Elective Ovariohysterectomy." Acta Scientiae Veterinariae 45, no. 1 (August 26, 2017): 6. http://dx.doi.org/10.22456/1679-9216.80443.
Full textAbstract:
Background: Total intravenous anesthesia with propofol is an alternative to inhalation anesthesia because it offers smoother anesthetic recovery, however, since propofol does not have adequate analgesic action, it is necessary to associate it with some drug to avoid the pain process. In addition, the combination may minimize cardiovascular depression resulting from continuous infusion of propofol by reducing infusion rate. The aim of this study was to evaluate cardiorespiratory parameters and anesthetic recovery in bitches submitted to continuous infusion of fentanyl, lidocaine and ketamine associated with total intravenous anesthesia with propofol and submitted to elective ovariohisterectomy.Materials, Methods & Results: Twenty-four bitches were medicated intramuscularly with 0.03 mg/kg of acepromazine. After 30 min, they were divided into three groups with different analgesic treatments: group F (GF) received a loading dose (LD) of 0.0036 mg/kg fentanyl, followed by continuous infusion of 0.0036 mg/kg/h; group L (GL), LD of 3 mg/kg lidocaine, followed by 3 mg/kg/h and group K (GK), LD of 0.6 mg/kg ketamine, followed by 0.6 mg/kg/h. First a LD of analgesic treatment was administered, followed by induction (to the effect) and beginning of continuous infusion of the analgesic treatment and propofol. The animals were intubated with endotracheal tube of adequate size, and connected to 100% oxygen, being kept under spontaneous ventilation during the entire period of anesthetic maintenance. The infusion of propofol started at 0.34 mg/kg/min and was adjusted so as to maintain the surgical anesthesia plane of Guedel and the cardiovascular parameters within the physiological limits for the species. The cardiorespiratory parameters were measured at different moments: basal (before application of any drug) and 5, 15, 20, 30, 40, 50, 60, 70 and 80 min after induction. The surgery started 20 min after anesthetic induction and lasted 60 min. At the end of the surgery, infusions were terminated and anesthesia recovery was evaluated by measuring the extubation time, sternal decubitus, and quadrupedal position in min. A variance analysis was performed to compare means of cardiorespiratory parameters for the moments and groups followed by the Scott-knott test. Differences were considered significant when P < 0.05. The baseline parameters, age, weight and dose of propofol IC were not statistically different between groups. The infusion rate of propofol increased in all groups from M5 to M15. GF and GL presented lower values for heart rate and GK presented higher values for the same variable. Blood pressure decreased after induction and increased in M40, M50 and M60. The variables EtCo2, PaCo2 and HCO3 increased and pH decreased showing respiratory depression in all groups. The mean time, in min, for orotracheal extubation, sternal decubitus and quadrupedal position were respectively 5 ± 3, 20 ± 6 and 39 ± 13 for GF; 6 ± 2, 23 ± 7 and 51 ± 15 for GL; 4 ± 2, 18 ± 6 and 42 ± 22 for GK and did not present statistical difference between the groups.Discussion: The combination of continuous infusion of fentanyl, lidocaine or ketamine to total intravenous anesthesia with propofol provides cardiovascular stability, but does not prevent respiratory function depression. The dose of propofol IC was the same in all groups, thus demonstrating that analgesics have the same potency in the transoperative period and justifies similar anesthetic recovery times. Thus, it can be concluded that these associations are feasible for total intravenous anesthesia provided proper monitorins for respiratory function.