Dissertations / Theses: 'Anesthesia complications'

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Van, Schoor Albert-Neels. "Paediatric regional anaesthetic procedures clinical anatomy competence, pitfalls and complications /." Pretoria : [s.n.], 2004. http://upetd.up.ac.za/thesis/available/etd07062005-151955.

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Newman, Lisa K. "The Association between BMI-for-age and Intra- and Post-General Anesthesia Airway Complications." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1337213041.

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Zeitz, Kathryn. "Post-operative observations, ritualised or vital in the detection of post-operative complications." Title page, contents and abstract only, 2003. http://web4.library.adelaide.edu.au/theses/09PH/09phz483.pdf.

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Copy of author's previously published work inserted. Includes bibliographical references (leaves 273-283). Aims to identify if the current practice of post-operative vital sign collection detects complications in the first 24 hours after the patient has returned to the general ward setting using a combination of methods within a triangulated approach to data collection.

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O'Connor, David C. "The Relationship Between Central Venous Catheter and Post-Operative Complications in Patients Undergoing Hepatic Resection." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5286.

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The Relationship Between Central Venous Catheter and Post-operative Complications in Patients Undergoing Hepatic Resection David C. O’Connor, Ph.D., DNAP, CRNA A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University Virginia Commonwealth University, 2018 Dissertation Chair: Clarence J. Biddle, Ph.D., CRNA Hepatic resection is indicated for primary and secondary malignancies. Use of a low central venous pressure technique is associated with decreased blood loss in these cases. This technique has evolved; central venous catheters and high dose morphine are no longer used, and patients are extubated earlier. The purpose of this study is to assess a relationship between these changes and outcomes. Central venous pressure has fallen out of favor as an accurate fluid measurement. Central venous catheters are associated with many complications. Outcomes in patients undergoing hepatic resection have improved over 20 years at one high volume institution. Guided by Donabedian’s theory of measuring outcomes, a non-randomized, non-experimental, retrospective, cohort design was conducted. The independent variables were intraoperative insertion of a central venous catheter, use of morphine, and time of extubation. The dependent variables were superficial and deep wound infections, number and severity of complications. The population sample is patients who submitted to partial hepatectomy at Memorial Sloan Kettering Cancer Center from 2007-2016. Data was obtained from hepatobiliary and anesthesia databases at Memorial Sloan Kettering Cancer Center. Data of 2518 from a possible 3903 patients were analyzed with chi square, univariate, Poisson and multivariate regressions. Univariate analysis for presence of CVC was significant for 90-day mortality (p 0.013). Use of morphine was significant for superficial wound infection (p 0.035), and a decrease in complications (p <.001). Amount of morphine was associated with fewer severe complications (p <.001). Incidental findings included a relationship between gender, total amount of fluids and number of segments resected. The significance of CVC with 90-day mortality was eliminated with stepwise multivariate regression. The findings support the change in anesthetic practice with clinical significance. Incidental findings regarding fluids and segments are supported in the literature. Future research should include goal directed fluid therapy and investigation of the relationship between gender and outcomes.

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Ulrici, Johanna. "Atemwegsassozierte Komplikationen bei übergewichtigen und adipösen Kindern in der Anästhesie." Doctoral thesis, Universitätsbibliothek Leipzig, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-86764.

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Übergewicht und Adipositas im Kindes- und Jugendalter sind Gesundheitsprobleme, die auch auf dem Gebiet der Anästhesie zunehmend relevant werden. In der vorliegenden Dissertationsschrift wurde untersucht, inwiefern übergewichtige Kinder und Jugendliche, im Vergleich zu nicht-übergewichtigen, Komplikationen des Atemwegsmanagementes und der Oxygenierung während einer Allgemeinanästhesie aufweisen und welche Bedeutung die Thematik in der deutschen Population für die Kinderanästhesie hat. Mit Hilfe spezieller Erfassungsbögen wurden folgende Parameter ermittelt und die übergewichtigen mit den nicht-übergewichtigen Studienteilnehmern verglichen: der Mallampati Score, schwierige Maskenventilation und Intubation, die Verwendung eines Atemwegshilfsmittels, der Cormack-Lehane Score und die Anzahl der Intubationsversuche. Daneben wurde die Inzidenz von Atemwegsobstruktionen (Broncho- und Laryngospasmen), Husten als Zeichen der Atemwegsirritation und Sauerstoffsättigungsabfälle um mehr als 10 % des Ausgangswertes erfasst. Es zeigte sich ein signifikant höherer Mallampati Score und ein signifikant häufigeres Auftreten von Husten (p < 0,05). Alle weiteren Parameter blieben ohne statistisch relevanten Unterschied, obwohl Atemwegshilfsmittel prozentual häufiger bei Übergewichtigen eingesetzt wurden. Bei einer gesonderten Analyse der in die Studie eingeschlossenen Untergewichtigen zeigte sich eine überraschend gehäufte Inzidenz hinsichtlich der schwierigen Laryngoskopie und einer Reintubation. Die verschiedenen Ursachen für die vorliegenden Ergebnisse werden in der Promotionsschrift detailliert diskutiert. Es wird insgesamt deutlich, dass nicht alleine Übergewicht und Adipositas ausschlaggebend für Atemwegskomplikationen sind, aber durchaus einen Risikofaktor darstellen. Darüber hinaus scheinen auch untergewichtige Kinder ein erhöhtes Risiko für Atemwegskomplikationen zu habe.

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Pereira, Ivan Dias Fernandes [UNESP]. "Complicações intra-operatórias das anestesias do neuroeixo realizadas de maio de 1990 a maio de 2008 na FMB-UNESP: análise retrospectiva." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/97726.

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Made available in DSpace on 2014-06-11T19:29:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-02-25Bitstream added on 2014-06-13T19:37:58Z : No. of bitstreams: 1 pereira_idf_me_botfm.pdf: 342153 bytes, checksum: d9563004493660e5ddc47166bc75326a (MD5)
A anestesia regional (AR) apresenta vantagens quando comparada à anestesia geral, como determinação de menor morbidade e mortalidade, analgesia pós-operatória de melhor qualidade e menor tempo de internação hospitalar. Diversas complicações podem ser decorrentes dos bloqueios do neuroeixo, algumas de maior gravidade, como as infecções do sistema nervoso central, lesões neurológicas devidas a hematomas espinhais, toxicidade pelos anestésicos locais ou trauma direto, e outras menos graves, como hipotensão e bradicardia, até mesmo consideradas fisiológicas. O objetivo desta pesquisa foi avaliar as complicações intra-operatórias desencadeadas pelos bloqueios do neuroeixo, em pacientes com idades iguais ou superiores a 18 anos submetidos a procedimentos não obstétricos, em um período de 18 anos, em hospital de atendimento terciário – Hospital das Clínicas da Faculdade de Medicina de Botucatu- UNESP. A partir do banco de dados do departamento de anestesiologia (Microsoft Access), foi realizada análise retrospectiva, de maio de 1990 a maio de 2008, de todas as complicações relacionadas às anestesias do neuroeixo (anestesias subaracnóidea simples e contínua, peridural simples e contínua e duplo bloqueio – raqui-peridural). As complicações encontradas foram: hipoxemia, hipoventilação, hipertensão arterial, hipotensão arterial, bradicardia sinusal, taquicardia sinusal, agitação, cefaléia, convulsão, oligúria, reação vaso-vagal, falha de bloqueio, perfuração acidental da dura-máter, disritmias ventriculares, parada cardíaca e óbito. Estas foram correlacionadas com a técnica anestésica, estado físico descrito pela Sociedade Americana de Anestesiologia (ASA), idade, sexo e comorbidades pré-operatórias, como hipertensão arterial, disritmias atriais e ventriculares, obesidade...
The regional anesthesia (RA) presents advantages when compared to the general anesthesia, as determination of smaller morbidity and mortality, postoperative analgesia of better quality and smaller time of hospitalar internment. Several complications can be resulting from the neuraxial blockades, some of larger gravity, as the infections of the central nervous system, neurological lesions owed to spinal or epidural hematomas, toxicity due to the local anesthetics or direct trauma, and other less serious, as hypotension and bradycardia, even considered physiological. The goal of this research was to assess the intraoperative complications caused by the neuraxial blockades in patients 18 years of age or older not submitted to obstetrician procedures, during a period of 18 years, in a hospital with tertiary treatment – Hospital das Clínicas da Faculdade de Medicina de Botucatu – UNESP. Starting from the database (Microsoft Access) of the Anesthesiology Department, retrospective analysis was accomplished, from May 1990 to May 2008, of some of the complications related to the neuraxial anesthesias (spinal, continuous spinal, epidural, continuous epidural and combined spinal-epidural anesthesias). The found complications were: hypoxemia, hypoventilation, arterial hypertension, arterial hypotension, sinusal bradycardia and tachycardia, agitation, headache, convulsion, oliguria, vasovagal reaction, blockade failure, accidental perforation of the duramater, ventricular dysrhythmias, cardiac arrest and death. These were correlated with the anesthetic technique, physical state described by the American Society of Anesthesiology (ASA), age, sex and preoperative comorbidities, as arterial hypertension, atrial and ventricular dysrhythmias, obesity, diabetes mellitus, coronary artery disease, congestive heart failure,... (Complete abstract click electronic access below)

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Snell, Jennifer Miranda. "Pediatric Emergence Delirium in the Postoperative Setting." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3921.

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Emergence delirium (ED), also known as emergence agitation, is a postoperative condition characterized by aberrant cognitive and psychomotor behaviors following general anesthesia. The incidence of ED is 3 to 8 times higher in children 5 years of age or less. There is no standard of nursing practice for managing ED symptoms in the pediatric surgical population. The purpose of this quality improvement project was to address a gap in knowledge needed to inform clinical decision-making when managing ED in the postoperative setting. Using an educational presentation for post anesthesia care unit (PACU) nurses, this project introduced the use of non-pharmacological interventions to mitigate symptoms of ED in the pediatric population as inspired by The Green Star Initiative, an Army program at Fort Carson. The project aim was to describe the effectiveness of ED-specific interventions from the nursing perspective. Using tenets of the Iowa model, this quality improvement project included a needs assessment survey, PowerPoint presentation, parent education leaflet, ED cheat sheet, and a post-intervention survey. Applying the context, input, process, product model for evaluation, this project increased knowledge of ED-specific interventions used by nurses that demonstrates a change in clinical decision-making. PACU nurses rated the interventions 43% effective on pediatric patients. This project addressed the gap in practice by providing structured education on ED, inspiring the use of ED-specific interventions, and promoting readiness to care for the pediatric surgical population. Outcomes add to the nursing literature by introducing ED-specific interventions to manage pediatric ED in facilities nationwide. A social implication of this project is to improve the care of pediatric surgical patients.

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Rodikov, Dragana. "Laryngospasm hos barn : riskfaktorer i samband med generell anestesi." Thesis, Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-16492.

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Laryngospasm är ett livshotande tillstånd hos barn som kan uppkomma i samband med generell anestesi. Hantering av luftvägen är den mest riskfyllda momentet inom barnanestesi. Syftet med studien var att undersöka vilka riskfaktorer för laryngospasm som finns hos barn vid generell anestesi. Undersökningen genomfördes som en litteraturstudie. Vid analys av fjorton artiklar framkom det i resultatet tre kategorier: anestesirelaterade riskfaktorer, patientrelaterade riskfaktorer och kirurgi-och procedur- relaterade riskfaktorer. Vid anestesirelateraderiskfaktorer framkom det fyra subkategorier; Stadier under anestesi där laryngospasm uppkommer och där är induktion en riskfaktor i denna subkategori. Den andra subkategorin handlar om utrustning för säkerställande av luftvägar där användandet av larynxmask är den största riskfaktorn. Tredje subkategorin behandlar anestesiläkemedel som risk för laryngospasm. Den mest betydande riskfaktorn är inhalationsanestesi. Den fjärde och sista subkategorin är anestesiologens erfarenhet och skicklighet. Det är viktigt att anestesipersonal har rutiner och riktlinjer för hur de skall identifiera, förebygga och behandla laryngospasm. Vidare är det av betydelse att erfaren anestesipersonal finns tillgänglig under hela anestesiförloppet när det föreligger risk för laryngospasm.
Laryngospasm is a life-threatening condition in children that may arise in connection with the anesthesia. Management of the airway is the most critical moment during anesthesia in children. The aim of the study was to investigate the risk factors for laryngospasm during general anesthesia. The survey was carried out as a literature review. The analyses of the fourteen articles resulted in three categories: anesthesia- related risk factors, patient-related risk factors and surgery-and procedure related risk factors. From the anesthesia-related risk factors revealed four subcategories; Stages during anesthesia where laryngospasm occurs and where induction is a risk factor in this subcategory. The second subcategory is about device for securing the airway which the use of larynx masks is the greatest risk factor. The third subcategory considering the risk of anesthesia drugs risk in laryngospasm. The most significant risk factor here is inhalation anaesthesia. The fourth subcategory is the anesthesiologist experience and skill. It is important that anesthesia professionals have routines and guidelines to identify, prevent and treat laryngospasm. Furthermore, it is important that experienced anaesthesia staff is available throughout the anesthetic process when there is a risk of laryngospasm.

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Pereira, Ivan Dias Fernandes. "Complicações intra-operatórias das anestesias do neuroeixo realizadas de maio de 1990 a maio de 2008 na FMB-UNESP : análise retrospectiva /." Botucatu : [s.n.], 2010. http://hdl.handle.net/11449/97726.

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Orientador: Eliana Marisa Ganem
Banca: Yara Marcondes Machado Castiglia
Banca: Flora Margarida Barra Bisinotto
Resumo: A anestesia regional (AR) apresenta vantagens quando comparada à anestesia geral, como determinação de menor morbidade e mortalidade, analgesia pós-operatória de melhor qualidade e menor tempo de internação hospitalar. Diversas complicações podem ser decorrentes dos bloqueios do neuroeixo, algumas de maior gravidade, como as infecções do sistema nervoso central, lesões neurológicas devidas a hematomas espinhais, toxicidade pelos anestésicos locais ou trauma direto, e outras menos graves, como hipotensão e bradicardia, até mesmo consideradas fisiológicas. O objetivo desta pesquisa foi avaliar as complicações intra-operatórias desencadeadas pelos bloqueios do neuroeixo, em pacientes com idades iguais ou superiores a 18 anos submetidos a procedimentos não obstétricos, em um período de 18 anos, em hospital de atendimento terciário - Hospital das Clínicas da Faculdade de Medicina de Botucatu- UNESP. A partir do banco de dados do departamento de anestesiologia (Microsoft Access), foi realizada análise retrospectiva, de maio de 1990 a maio de 2008, de todas as complicações relacionadas às anestesias do neuroeixo (anestesias subaracnóidea simples e contínua, peridural simples e contínua e duplo bloqueio - raqui-peridural). As complicações encontradas foram: hipoxemia, hipoventilação, hipertensão arterial, hipotensão arterial, bradicardia sinusal, taquicardia sinusal, agitação, cefaléia, convulsão, oligúria, reação vaso-vagal, falha de bloqueio, perfuração acidental da dura-máter, disritmias ventriculares, parada cardíaca e óbito. Estas foram correlacionadas com a técnica anestésica, estado físico descrito pela Sociedade Americana de Anestesiologia (ASA), idade, sexo e comorbidades pré-operatórias, como hipertensão arterial, disritmias atriais e ventriculares, obesidade... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The regional anesthesia (RA) presents advantages when compared to the general anesthesia, as determination of smaller morbidity and mortality, postoperative analgesia of better quality and smaller time of hospitalar internment. Several complications can be resulting from the neuraxial blockades, some of larger gravity, as the infections of the central nervous system, neurological lesions owed to spinal or epidural hematomas, toxicity due to the local anesthetics or direct trauma, and other less serious, as hypotension and bradycardia, even considered physiological. The goal of this research was to assess the intraoperative complications caused by the neuraxial blockades in patients 18 years of age or older not submitted to obstetrician procedures, during a period of 18 years, in a hospital with tertiary treatment - Hospital das Clínicas da Faculdade de Medicina de Botucatu - UNESP. Starting from the database (Microsoft Access) of the Anesthesiology Department, retrospective analysis was accomplished, from May 1990 to May 2008, of some of the complications related to the neuraxial anesthesias (spinal, continuous spinal, epidural, continuous epidural and combined spinal-epidural anesthesias). The found complications were: hypoxemia, hypoventilation, arterial hypertension, arterial hypotension, sinusal bradycardia and tachycardia, agitation, headache, convulsion, oliguria, vasovagal reaction, blockade failure, accidental perforation of the duramater, ventricular dysrhythmias, cardiac arrest and death. These were correlated with the anesthetic technique, physical state described by the American Society of Anesthesiology (ASA), age, sex and preoperative comorbidities, as arterial hypertension, atrial and ventricular dysrhythmias, obesity, diabetes mellitus, coronary artery disease, congestive heart failure,... (Complete abstract click electronic access below)
Mestre

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Schwerdtfeger, Cristiane Milanezi Marques de Almeida. "Faringoplastias: influências das medicações utilizadas em anestesia e complicações no período pós-operatório precoce." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/61/61131/tde-22092006-153459/.

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objetivos: considerando a importância e a eficácia das faringoplastias como cirurgias reabilitadoras da fala e a importância dos aspectos anestésicos para um resultado cirúrgico adequado, este estudo objetiva documentar as intercorrências relativas às cirurgias de retalho faríngeo e seu possível envolvimento com os fatores anestésicos. Método: estudo retrospectivo e descritivo. Foram analisados 2679 prontuários de pacientes submetidos a faringoplastias, no Hospital de Reabilitação de Anomalias Craniofaciais- Universidade se São Paulo (HRAC-USP), entre 1980 e 2003. Foram selecionados os 2299 casos em que a técnica utilizada foi a do retalho faríngeo posterior e foram coletados parâmetros clínicos e sintomas sugestivos de complicações: permeabilidade de via aérea, sangramento, dor, náusea e vômito, agitação psicomotora, temperatura, pressão arterial e saturação de oxigênio. Resultados: dos 2299 procedimentos, 1042 apresentaram complicações. Vômito (16,31%) e dor (14,31%) foram as mais freqüentes. Complicações consideradas mais críticas, como obstrução de via aérea e hemorragia foram menos freqüentes, ocorrendo em 4,78% e 3,87% dos 2299 pacientes operados. As complicações mais críticas foram as determinantes da necessidade de reoperação no período pós-operatório precoce, ocorrendo em 39 pacientes. As menores chances de ocorrência de complicações foram verificadas com o anestésico inalatório sevoflurano, com o agente indutor propofol, com opióides na indução anestésica, com os analgésicos tramadol e nalbufina e com o antiemético ondansetron. Conclusão: houve associação entre medicações administradas na anestesia e ocorrência ou ausência de complicações no período pós-operatório precoce. O esquema medicamentoso, utilizado desde 1995, incluindo sevoflurano, propofol, opióides na indução, tramadol, nalbufina e ondansetron, é o que melhor atende às necessidades dos pacientes e anestesiologistas para cirurgia do retalho faríngeo, no HRAC-USP.
Objectives: considering the valuable and effectiveness of pharyngoplasty like surgical procedure designed to correct velopharyngeal dysfunction and the importance of anesthetic aspects in any surgery outcome, this study aimed to assess complications rates and a possible association with drugs used by anesthetist. Study design: we conducted a 23-year retrospective study at a tertiary craniofacial center: Hospital de Reabilitação de Anomalias Cranifaciais Universidade de São Paulo (HRACUSP). Two thousand six hundred seventy nine patients charts between 1980 and 2003 were reviewed. Charts were selected when the posterior pharyngeal flap surgery was performed (2299 charts). Clinical parameters and symptoms linked to perioperative complications were collected: airway permeability, bleeding, pain, vomiting, agitation, temperature, arterial pressure and oxygen saturation. Results: from 2299 pharyngeal flaps, 1042 showed early postoperative complications. The most common complications were vomiting (16,31%) and pain (14,31%). Most critical complications were less frequent: airway obstruction occurred in 4,78% of all patients and bleeding occurred at a rate of 3,87%. Just 39 patients needed reoperation to control these critical complications. The best results with a low complications rate were achieved when anesthetist used sevoflurane, propofol, opioids in anesthesia induction, tramadol, nalbufine and ondansetron Conclusions: there was association between anesthetic drugs and early post operative complications. The drugs scheme (sevoflurane, propofol, opioids, tramadol, nalbufine, ondansetron) used by HRAC-USP anesthetists team since 1995 has been proved effective and appropriate.

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Ekdahl, Manne, and Åsa Nordling. "Perioperativa åtgärder för att lindra och förebygga postoperativ halsont och heshet hos patienter som genomgått generell anestesi." Thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-389344.

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Bakgrund: Halsont och heshet är några av de vanligaste postoperativa komplikationerna hos patienter som erhållit endotrakealtub eller larynxmask under generell anestesi. Syfte: Att kartlägga anestesisjuksköterskans perioperativa åtgärder för att förebygga och lindra patientens postoperativa halsont och heshet. Metod: En litteraturöversikt med deskriptiv design. Resultat sammanställdes utifrån 18 granskade artiklar av kvantitativ ansats, eftersökta i databaserna PudMed och Cinahl. Resultat: Litteraturöversikten visade flertalet åtgärder som kunde minska både incidens och svårighetsgrad av postoperativ halsont och heshet. En mindre endotrakealtub, användning av kontinuerlig tryckregulator, administrering av glukokortikoider och användning av larynxmask gav minskad incidens av halsont och heshet. Även videolaryngoskop, minskad kraft vid extraktion av ledare och vissa naturläkemedel visade sig minska incidensen. Åtgärderna visade på goda effekter i nära anslutning till operationen och inom första postoperativa dygnet, emellertid gav få artiklar resultat med bibehållen effekt över tid. Slutsats: Studien gav goda indikationer för åtgärder som kunde minska patienters förekomst av halsont och heshet och därigenom deras lidande. Resultatet visade på stor spridning vilket gjorde det svårt bedöma vilka åtgärder som var lämpliga att applicera i kliniken. Att minska storleken på endotrakealtuben och använda larynxmask när operationen tillåter var åtgärder som ansågs användbara. Även användning av glukokortikoider/antiinflammatoriska läkemedel samt att i större utsträckning utnyttja videolaryngoskopstekniken ansågs som adekvata åtgärder för att minska patientens lidande orsakat av postoperativ halsont och heshet.
Background: Sore throat and hoarseness are some of the most common postoperative complications in patients receiving endotracheal tube or laryngeal mask during general anesthesia. Aim: To investigate the anesthetic nurse's perioperative measures to prevent and alleviate the patient's suffering from postoperative sore throat and hoarseness. Method: A literature review with descriptive design. Results were compiled based on 18 articles of quantitative approaches, requested in the databases PudMed and Cinahl. Result: The literature review showed several measures that could reduce both incidence and severity of postoperative sore throat and hoarseness. A minor endotracheal tube, the use of continuous cuff pressure regulator, administration of glucocorticoids and use of laryngeal mask reduced the incidence of sore throat and hoarseness. Also, video laryngoscopes, reduced force when extracting stylet removal and some herbal medications seemed to give good results in reducing the incidence. The measures showed good effects close to surgery and within the first postoperative day, however, few studies gave results with retained effect over time. Conclusions: The study provided good indications for measures that could reduce patients' incidence of sore throat and hoarseness and thereby their suffering. The results showed a large spread, which made it difficult to assess which measures were suitable for application in the clinic. Reducing the size of the endotracheal tube and using the laryngeal mask when the operation allows was implications that considered useful. Also, the use of glucocorticoids / anti-inflammatory drugs and to a greater extent utilizing the video laryngoscope technique was considered adequate measures to reduce the suffering of patients caused by postoperative sore throat and hoarseness.

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Nilsson, Johan, and Emil Lindström. "Patientens upplevelse av oavsiktlig vakenhet i generell anestesi : En systematisk integrativ litteraturstudie." Thesis, Linnéuniversitetet, Institutionen för hälso- och vårdvetenskap (HV), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-82379.

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Bakgrund: Awareness, oavsiktlig vakenhet, är en ovanlig men allvarlig komplikation vid generell anestesi. Awarenessupplevelsen kan vara traumatisk för patienterna och resultera i långvarig ohälsa. Patienterna har rätt till god vård och anestesisjuksköterskan är ansvarig för att patienterna är adekvat sövda under hela sin anestesi. Syfte: Att belysa patientens upplevelse av awareness under generell anestesi samt vilka konsekvenser det kan resultera i för patienten Metod: En systematisk integrativ litteraturstudie genomfördes. Litteratursökningar gjordes i databaserna Cinahl, PubMed och PsycINFO. 36 kvalitativa och kvantitativa studier identifierades och analyserades med tematisk syntes. Resultat: Fyra övergripande analytiska teman framkom. Dessa var sensoriska intryck, existentiella känslor, påkalla uppmärksamhet och psykisk ohälsa. De tre första temana berör patientens upplevelse i samband med awareness och det sista temat berör vilka konsekvenser denna upplevelse kunde få för patienterna. I samband med awareness kunde patienterna uppleva olika sensoriska intryck som hörsel, syn, känsel, smärta och paralys. Dessa upplevelser kunde medföra existentiella känslor som rädsla, oro, ångest, panik och hjälplöshet. Flera patienter beskrev hur de försökte påkalla personalens uppmärksamhet. Upplevelsen av awareness var för en del patienter en traumatisk upplevelse som kunde medföra kortvarig eller långvarig psykisk ohälsa av varierande omfattning. Det kunde även medföra psykosociala konsekvenser med försämrade relationer till närstående och hälso- och sjukvården med följden att patienten ej kunde genomföra rekommenderad behandling. Slutsats: Att uppleva awareness kan innebära ett lidande för patienten. En ökad kunskap om awareness medvetandegör behovet av att förebygga awareness och ökar anestesisjuksköterskans möjlighet att identifiera och stötta patienter som drabbats.
Background: Awareness, (e.g. unintentional wakefullness) is an unusual but serious complication during general anesthesia. The awareness experience can be traumatic for the patients and result in long-term illness. The patients are entitled to good care and the anesthetist nurse is responsible for ensuring that the patients are adequately anesthetized throughout their anesthesia. Aim: The aim was to illustrate the patient’s perception of awareness during general anesthesia and the consequences this may have for the patient. Method: A systematic integrative literature study was conducted. Literature searches were made in the databases CINAHL, PubMed and PsycINFO. 36 qualitative and quantitative studies were identified and analyzed with thematic synthesis. Result: Four comprehensive analytical themes emerged. These were Sensory impressions, existential feelings, calling for attention and mental illness. The first three themes concern the patient’s experience in relation to awareness and the last theme concerns what consequences this experience could have for the patients. In conjunction with awareness patients could experience different sensory impressions such as hearing, sight, feeling, pain and paralysis. These experiences could cause existential feelings such as fear, anxiety, panic and helplessness. Several patients described how they tried to call on the staff’s attention. The experience of awareness was for some patients a traumatic experience that could cause short-term or longterm psychological sequele of varying degrees. It could also result in psychosocial consequences with deteriorated relationships with both relatives and health care, with the result that the patient could not carry out recommended treatment. Conclusion: Experiencing awareness may mean a suffering for the patient. An increased knowledge about awareness acknowledges the need to prevent it and increases the ability of the nurse to identify and support patients who are affected.

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Mendoza, Isabel Yovana Quispe. "Paciente idoso cirúrgico: complicações no período de recuperação pós-anestésica." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/7/7139/tde-15012007-122326/.

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Este estudo tem como objetivos, identificar os fatores de risco de maior incidência no paciente idoso cirúrgico nos períodos pré-operatório e intra-operatório, identificar as complicações mais freqüentes no paciente idoso cirúrgico no período de recuperação pós-anestésica e relacionar as complicações mais freqüentes do paciente idoso cirúrgico no período de recuperação pós-anestésica aos fatores de risco de maior incidência do paciente idoso cirúrgico nos períodos pré-operatório e intra-operatório. A amostra foi constituído por 110 prontuários de pacientes idosos submetidos a cirurgia durante o ano 2004, que obedeciam os seguintes critérios de inclusão: idosos de ambos sexos, idosos submetidos a cirurgias eletivas, de emergência e urgência. Procedeu-se à coleta de dados, utilizando-se um formulário, a fim de contemplar os objetivos deste estudo. Os resultados mostraram que, 62 (56,4%) eram do sexo masculino; 63 (57,3%) pacientes estavam na faixa etária de 70 a 79 anos; 36 (32,7%) com hipertensão arterial sistêmica; 66 (60%) classificados como ASA II. Referente a fatores de risco relacionado ao período intraoperatório, em 69 (62,7%) pacientes o tempo de cirurgia foi inferior a três horas; 90 pacientes (81,8%) foram posicionados em decúbito dorsal horizontal na mesa cirúrgica; 59 pacientes (53,6%) foram submetidos à cirurgia abdominal e 56 (50,9%) idosos foram submetidos à anestesia geral. Quanto às complicações na sala de recuperação pós-anestésica: (55,5%) apresentaram hipotermia, 48 (43,6%) dor e 40 (36,4%) desenvolveram hipertensão arterial no período pós-operatório. De acordo com os resultados da análise de regressão logística, o sexo masculino e feminino apresentou associação estatisticamente significante com todas as complicações na sala recuperação pós-anestésica, evidenciou-se, maior associação entre os idosos de 70 a 79 anos com a apresentação de dispnéia (OR= 2,78) e idosos de 80 a 89 anos apresentou maior associação com taquicardia (OR= 1,40). Não se obteve associação entre os idosos com idade acima de 90 anos com as complicações investigadas. Quanto à hipertensão arterial, o estágio II obteve maior associação com bradicardia (OR= 8,01); assim como o escore ASA categorias II e III incrementam a possibilidade de apresentar hipertensão arterial no período de recuperação pós-anestésica (OR= 4,79; 10,71) respectivamente,. Em relação à associação entre as complicações mais freqüentes na recuperação pós-anestésica com os fatores de risco relacionados ao paciente cirúrgico idoso no período intra-operatório, o tempo de cirurgia superior a cinco horas teve maior associação com hipertensão arterial (OR = 6,49) quando comparado às cirurgias com duração entre 3 a 5 horas e inferior a 3 horas. A posição decúbito lateral apresentou maior associação com hipotermia, náusea, vômito e dor (OR = 6,68; 5,79; 3,12), respectivamente, quando comparado às posições decúbito dorsal horizontal e litotômica. Dentre os tipos de cirurgia, a artroplastia teve maior associação com náusea e vômito (OR = 7,64) seguida de redução de fratura com taquicardia e dor (OR = 3,71 e 2,05), respectivamente. Quando realizada a associação entre o tipo de anestesia e complicações na recuperação pós-anestésica ,a anestesia raquidiana apresentou maior associação com taquicardia (OR = 4,24), quando comparada à anestesia geral e peridural. Sendo assim, os pacientes idosos constituem-se em um desafio para a equipe de saúde em sala de recuperação pós-anestésica, os quais devem levar em conta a alta prevalência de doenças associadas e as alterações funcionais decorrentes do processo de envelhecimento
This study has as its goals to identify the most common risk factors for aging surgical patients in the pre-operatory and intra-operatory periods; to identify the most frequent complications in aging surgical patients in the post-anesthetic period; and make the relation between the most frequent complications in the post-anesthetic period for aging surgical patients with the most common risk factors in the pre-operatory and intra-operatory periods. The sample was comprised of 110 records of aging patients submitted to surgery during 2004, which complied with the following inclusion criteria: aging of both sex; aging submitted to elective, emergency and urgency. Data was gathered through a form that includes socio-demographic data, aspects related to the patient, aspects related to the intra-operatory period, and aspects related to the complications in the post-anesthetic recovery. The results showed that 62 (56.4%) patients were male; 63 (57.3%) were in the age group from 70 to 79 years old; 36 (32.7%) suffered from systemic artery hypertension; 66 (60%) classified as ASA II. Concerning the risk factors related to the intra-operatory period, in 69 (62.7%) patients surgery time was under three hours; 90 patients (81.8%) were positioned lying on the side on the operation table; 59 patients (53.6%) underwent abdominal surgery; and 56 (50.9%) patients had general anesthesia. In regards to complications in the post-anesthetic recovery room: (55.5%) experienced hypothermia, 48 (43.6%), pain, and 40 (36.4%) developed artery hypertension in the post-operatory period. According to the result of the logistics regression analysis, males and females showed statistically significant association with all the complications in the post-anesthetic recovery room; it was evidenced more association among the aged from 70 to 79 years old with dyspnea (OR= 2.78), while patients from 80 to 89 years old had more association with tachycardia (OR= 1.40). There was no association among patients older than 90 with the researched complications. Regarding artery hypertension, stage II got more association with bradycardia (OR= 8.01); as the ASA score categories II and III increase the possibility of presenting artery hypertension in the post-anesthetic recovery period (OR= 4.79; 10.71) respectively. Regarding the association between the most frequent complications in the post-anesthetic recovery with the risk factors related to aging surgery patients in the intra-operatory period, surgery time exceeding five hours had more association with artery hypertension (OR = 6.49) when compared with 3 to 5 hour-surgeries and less than 3-hour surgeries. The lateral decubitus position showed more association with hypothermia, nausea, vomiting and pain (OR = 6.68; 5.79; 3.12), respectively, when compared with the lying horizontally on the side and lithotomic positions. Among the types of surgeries, arthroplasty had more association with nausea and vomit (OR = 7.64), followed by fracture reduction with tachycardia and pain (OR = 3.71 and 2.05), respectively. When the association between the kind of anesthesia and complications in the post-anesthetic recovery is made, rachidian showed more association with tachycardia (OR = 4.24), when compared with general anesthesia and peridural. Thus aging patients in the post-anesthetic recovery period are a challenge for the health team, which must take into account the high prevalence of associated diseases and the functional alterations resulting from the aging process

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Aroke, Edwin N. "A Pilot Study of the Pharmacogenetics of Ketamine-Induced Emergence Phenomena: A Dissertation." eScholarship@UMMS, 2016. https://escholarship.umassmed.edu/gsn_diss/43.

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Background: Up to 55% of patients administered ketamine, experience an emergence phenomena (EP) that closely mimics schizophrenia and increases their risk of injury. While genetics accounts for about 50% of severe adverse drug reactions, no studies have investigated genetic association of ketamine-induced EP in healthy patients. Ketamine is metabolized by CYP 2B6 enzymes and CYP 2B^8^ allele significantly alter ketamine metabolism. In addition, ketamine exerts most of its effects by inhibiting the N-methyl-D-aspartate receptor (NMADR), and NMDAR genes (GRIN2B) are associated with learning and memory impairment and schizophrenia. Purpose: To investigate the relationship between CYP2B6*6 and GRIN2B single nucleotide polymorphisms (SNPs) and ketamine-induced emergence phenomena (EP). Methods: This cross-sectional pharmacogenetic study recruited 75 patients having minor orthopedic, hand, foot, anorectal surgeries from two outpatient surgical centers. EP was measured with the Clinician Administered Dissociative State Scale (CADSS). DNA was genotyped using standard Taqman assays and protocols. Genetic association of CYP2B6*6 and GRIN2B (rs1019385 & rs1806191) SNPs and ketamine induced EP occurrence and severity were tested using multivariate logistic and linear regression, adjusting for age, ketamine dose, duration of anesthesia, and time since ketamine administration. Results: Forty-seven patients (63%) received ketamine and were genotyped. Nineteen EP cases were identified (CADSS > 4), leaving 28 non-EP controls. For our population, CADSS has an internal consistency reliability Cronbach’s alpha of 0.82, and could reliably distinguish ketamine from non-ketamine cases. Occurrence and severity of EP were not associated with CYP2B6*6 or GRIN2B (p > 0.1). Models removing genotype and containing age, ketamine dose, duration of v anesthesia, and time since ketamine administration significantly predicted EP occurrence (p = 0.001) and severity (p = 0.007). Presence and severity of EP did not affect patient satisfaction with care. Discussion: Younger age, higher dose and longer duration of anesthesia significantly predicted EP occurrence and severity among our sample. This study provides effect size estimates useful for the design of adequately powered future genetic association studies. The feasibility of recruitment from patients undergoing elective, outpatient surgeries and ease of post-operative EP assessment with CADSS supports our approach. However, the small sample size may have limited about ability to determine significant differences. Conclusion: Fully powered studies are needed to investigate this important phenomena. Determining factors for anesthesia-related EP symptoms may reduce risks and costs associated with this adverse medication effect.

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Ijbara, Manhal. "An assessment of comprehensive dental treatment provided under general anaesthesia at Tygerberg Oral Health Centre." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_7118_1210745626.

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There are several categories of dental problems in children that cannot be treated optimally in the office settings and are best managed in the hospital theatre. The ability to treat children in the hospital environment in order to provide comprehensive dental care using general anaesthesia(GA) is a valuable option to the paediatric dentist, despite some degree of risk to the patient. General anaesthesia provides optimum conditions for restorative treatment such as maximum contamination control, immobilization of the patient, efficiency and effectiveness, and elimination of reflexes.

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Blåder, Karin, and Karl Sunneskär. "Påverkar val av anestesimedel den dagkirurgiska patientens postoperativa återhämtning? : En jämförelse mellan Propofol och Sevofluran." Thesis, Högskolan i Borås, Akademin för vård, arbetsliv och välfärd, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-26285.

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Intravenös anestesi med Propofol eller inhalationsanestesi med gasen Sevofluran är de två vanligaste anestesiformerna i Sverige. Syftet med studien vara att undersöka om patienters postoperativa återhämtning skiljer sig åt beroende på om de sövts med Propofol eller Sevofluran. Datainsamlingen till studien genomfördes med systematisk litteraturöversikt baserad på integrativ metod. Både kvalitativa och kvantitativa studier samlades in, men enbart kvantitativa artiklar inkluderades. Resultatet visade att det under den postoperativa återhämtningen var vanligt förekommande med två postoperativa komplikationer, smärta samt illamående och kräkningar. Resultatet visar inga statistiskt signifikanta skillnader när det gällde dessa beroende på val av anestesimedel. Men vidare studier behövs inom ämnet, framför allt om kön eller ålder kan vara ytterligare påverkande faktorer.
Intravenous anesthesia with Propofol or inhalation anesthesia with the gas Sevoflurane are the two most common forms of anesthesia in Sweden. The purpose of the study was to investigate whether patient's postoperative recovery differs depending on whether they have been anesthetized with Propofol or Sevoflurane. The data collection for the study was carried out with a systematic literature review based on integrative research Both qualitative and quantitative studies were collected, but only quantitative articles were included. The results showed that during postoperative recovery it was common with two postoperative complications, pain, nausea, and vomiting. The results show no statistically significant differences in these depending on the choice of anesthetic agents. However, further studies are needed in the subject, especially if gender or age can be additional influencers.

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Biboulet, Philippe. "Épidémiologie et complications de 102468 anesthésies : exploitation d'une fiche informatisée au C.H.R. de Montpellier." Montpellier 1, 1989. http://www.theses.fr/1989MON11082.

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Nemoz, Romain Verwaerde Patrick. "Etude des complications liées aux techniques d'anesthésie péridurale chez le cheval." [S.l.] : [s.n.], 2007. http://oatao.univ-toulouse.fr/1757/1/debouch_1757.pdf.

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Rafiq, Muhammad. "Post-operative dysregulation of Brain-Derived Neurotrophic Factor (BDNF) in cortex and hippocampus of rats." Thesis, Strasbourg, 2013. http://www.theses.fr/2013STRAJ127/document.

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Le Brain-derived Neurotrophic Factor (BDNF) est impliqué dans les processus cognitifs impliquant l'hippocampe et les structures corticales. Cette étude avait pour but d’analyser les effets postopératoires sur l’expression du BDNF dans ces structures cérébrales.Ainsi, les effets d’une anesthésie de courte durée au propofol, d’une chirurgie mineure et du lipopolysaccharide (LPS) sur l'altération de l’expression du BDNF ont été analysée dans l'hippocampe et le cortex de deux modèles de rongeurs nocturnes et diurnes, correspondant respectivement des jeunes rats Sprague Dawley mâles et des Arvicanthis ansorgei.Dans un premier temps, la rythmicité nycthémérale de l’expression du BDNF a été analysée.Les quantités de BDNF présentes dans le cortex et l'hippocampe ont été déterminées par une technique ELISA. Il s’est avéré que, dans l'hippocampe et le cortex de rat et d’A. ansorgei, le BDNF suit une rythmicité sur 24 heures. La quantité de BDNF atteint un maximum à ZT5(i.e., 5 heures après le début de l’exposition à la lumière). Dans un deuxième temps, les effets sur l’expression du BDNF ont été analysés après administration de propofol et/ou LPS, ainsi que lors d’une chirurgie légère. Parallèlement,l’impact de ces traitements sur la mémoire a été testé à l’aide d’un test d'évitement passif.Nos résultats indiquent que la quantité de BDNF est régulée positivement dans l'hippocampe et le cortex de rats lorsque les animaux ont subit une anesthésie de courte durée au propofol en présence ou absence de LPS. A l’opposé, une chirurgie mineure (sous anesthésie propofol)n’a aucun effet sur les quantités de BDNF.En conclusion, ces études mettent en évidence des effets majeurs d’une anesthésie sur l’expression du BDNF, ainsi que les effets protecteurs du propofol sur la neuroinflammation induite par le LPS
Brain-derived neurotrophic factor (BDNF) is involved in cognition and hippocampus and cortical structures are important in cognition. The present study was designed to analyse the post-operative effects on BDNF. For this purpose, we examined the effects of short duration propofol anaesthesia, LPS and minor surgery on the BDNF protein alteration in the hippocampus and cortex.Young male Sprague Dawley rats were used in all experiments except Arvicanthis ansorgei which were used to study the circadian rhythmicity of BDNF protein as model for diurnal rodents. The quantity of BDNF protein present in the cortex and hippocampal supernatants was determined with an ELISA technique. Memory was tested by fear conditioning using the classic fear conditioning preparation (passive avoidance apparatus).The major finding on BDNF protein in control conditions is that the BDNF protein followed a circadian rhythmicity during the 24 hours of day in the rat’s hippocampus and cortex. The concentration of BDNF protein has been observed to reach a maximum at ZT5 (5 hours afterthe light on period) whether the animals were nocturnal or diurnal. In addition, we found that BDNF protein amount is up regulated in the hippocampus and cortex of rats when they were submitted to short duration propofol anaesthesia, as well as LPS and no effect when minor surgery under propofol anaesthesia was performed.In conclusion, these studies illustrate the dramatic effects of post-operative conditions and neuroinflammation induced by LPS on cognition and the potential mechanism involved. This study also suggests the protective effects of the short duration propofol anaesthesia against neuroinflammation induced by LPS

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SEMENOFF, CAMUS NADINE. "Anesthesie et dystrophie myotonique de steinert : risques et complications ; a propos de 12 cas." Besançon, 1992. http://www.theses.fr/1992BESA3084.

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Silva, Débora Cristina Pinto. "Segurança do paciente no período pós-operatório imediato na sala de recuperação pós-anestésica." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/7/7139/tde-13062008-100842/.

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Acredita-se que a segurança do paciente na SRPA depende não só de equipamentos e recursos tecnológicos, mas de recursos humanos, que desenvolvam procedimentos e intervenções de enfermagem, pautados em conhecimento prático e científico, evitando, assim, a ocorrência de eventos adversos e complicações decorrentes da alta complexidade inerente ao processo anestésico-cirúrgico. Sendo assim, os objetivos desse estudo foram: caracterizar os pacientes em SRPA sociodemograficamente; identificar as complicações mais freqüentes; relacionar as complicações às intervenções de enfermagem realizadas; relacionar o esquema de jornada de trabalho dos enfermeiros às complicações. A amostra é composta por 400 prontuários de pacientes maiores de 18 anos, submetidos a procedimentos cirúrgicos de grande e médio porte, admitidos na unidade de SRPA, com tempo de permanência superior à uma hora. O teste de Kolmogorov-Smirnov foi aplicado para testar a normalidade de variáveis quantitativas. O teste exato de Fisher-Freeman-Halton foi utilizado na comparação de proporções em tabelas de contingência maiores que 2x2. Todas as probabilidades de significância com valores de p<0,005 como estatisticamente significantes. Os resultados mostram que a maioria dos pacientes é do sexo masculino, com idade média de 53,3 anos (Dp=16,9 anos), com doença sistêmica leve ou moderada, sem limitação funcional. A comorbidade mais freqüente foi a hipertensão arterial sistêmica (40,7%). As cirurgias mais realizadas foram gerais (62,7%) que incluíram abdominais, urológicas, ginecológicas, e vasculares de grande porte. A anestesia, predominante, foi geral (92,2%). Tempo de permanência em média 111,6 minutos (Dp=67,8). As complicações mais freqüentes foram dor (54%) e hipotermia (43%). Algumas complicações apresentaram relação estatisticamente significante com relação à intervenção de enfermagem como dor e rotina(p<0,0001); dor e oxigenioterapia (p 0,0013); dor e medicação(p 0,0001) e dor e curativo (p<0,0005). Outra complicação que significante foi agitação/ansiedade com intervenção de enfermagem de rotina (p 0,0194) e agitação/ansiedade com oxigenioterapia (p 0,0099). A complicação hipotensão relacionou-se positivamente com a intervenção de enfermagem hidratação (p<0,0005); exames complementares ( p 0,0381) e observação(p 0,0141). A hipertensão apresentou-se estatisticamente significante somente com a relação à observação (p<0,0005). O tremor apresentou relação, significativa com a colocação de manta térmica (p 0,0171) e transfusão sangüínea (p 0,0445); náuseas e vômitos relacionaram-se com a intervenção rotina(p 0,0004), medicação(p<0,0001) e sondagem vesical de alívio(p 0,0224). O sangramento respondeu significantemente à intervenção de rotina (p 0,0064), medicação (p 0,0008) e curativos (p<0,0005). A hipoxemia foi, estatisticamente significante quando relacionada à rotina(p 0,0002) e a oxigenioterapia (p<0,0001). A hipotermia teve uma relação significativa com rotina (p<0,0001), manta térmica (p<0,0001), medicação (p<0,0001). Dor (p 0,0224), náuseas e vômitos (p 0,0131), agitação (p 0,0490) e sangramento (p 0,0001) são complicações que se relacionaram significativamente de forma positiva à jornada de trabalho quando se fixou um enfermeiro na SRPA
There is a believe that patient security at SRPA depends not only on equipments and technological resources, but from human resources that develop procedures and nursing interventions based on practical and scientific knowledge, avoiding adverse events occurrences and complications due to the high complexity inherent in the surgical-anesthesia process. So, the objectives of this study were: characterize SRPA patients socio-demographically; identify the most frequent complications; relate complications to nursing interventions proceeded; relate nurses working journey to complications. The sample is composed by 400 over 18 years old patients\' records, submitted to big/medium surgical procedures, admitted at SRPA unit, standing there for more then one hour. The Kolmogorov-Smirnov test was used to test quantity variables normality. The Fisher-Freeman-Halton exact test was used to compare the proportions on tables bigger then 2x2. All probabilities with significance values from p<0.005 were considered statistically significant. Results show that most of the patients are male, average age 53.3 years old (dP=16.9 years old), with light or moderate systemic ill without functional limitations. Most frequent comorbidity is systemic arterial hypertension (40.7%). Most frequent surgeries were general surgeries (62.7%) which included abdominal, urological, gynecological, and big vascular ones. General anesthesia was the predominant one (92.2%). Average staying time 111.6 minutes (dP=67.8). Most frequent complications were pain (54%) and hypodermis (43%). Some complications showed significant statistical relation between the nursing intervention such as pain and routine (p<0.0001); pain and oxigentherapy (p<0.0013); pain and medication (p<0.0001) and pain and curative (p<0.0005). Another significant complication was agitation/anxiety with a nursing routine intervention (p<0.0194) and agitation/anxiety with oxigentherapy (p<0.0099). Hypotension complication was positively related with the hydrate nursing intervention (p<0.0005); complementary tests (p<0.0381) and observation (p<0.0141). Hypertension was presented statistically significant just related to the observation (p<0.0005). Tremble presented significant relation with using a thermal blanket (p 0.0171) and blood transfusion (p 0.0445); sickness and vomit were related to routine intervention (p 0.0004), medication (p<0.0001) and relieve bladder poll (p 0.0224). Bleeding responded significantly to routine intervention (p 0.0064), medication (p 0.0008) and curatives (p<0.0005). Hypoxemia was statistically significant when related to routine (p 0.0002) and oxygentherapy (p<0.0001). Hypothermia was significantly related to routine (p<0.0001), thermal blanket (p<0.0001), medication (p<0.0001). Pain (p 0.0224), sickness and vomit (p 0.0131), agitation (p 0.0490) and bleeding (p 0.0001) are complications that are significantly positively related to working journey when a nurse was fixed at the SRPA

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Neto, Ary Serpa. "Papel da estratégia protetora de ventilação mecânica na lesão pulmonar induzida pelo ventilador mecânico em pacientes sem síndrome do desconforto respiratório agudo: uma meta-análise de dados individuais de pacientes." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-09122014-122810/.

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INTRODUÇÃO: Estudos recentes sugerem que o uso da estratégia protetora de ventilação mecânica no intra-operatório pode reduzir a incidência de complicações pulmonares pós-operatórias (CPP). O objetivo desta meta-análise de dados individuais de pacientes é avaliar o efeito independente do volume corrente e da pressão positiva ao final da expiração (PEEP) na ocorrência de CPP. MÉTODOS: Foram incluídos ensaios clínicos randomizados que compararam a estratégia protetora de ventilação mecânica com a estratégia convencional em pacientes submetidos à anestesia para cirurgia. O desfecho primário foi o desenvolvimento de CPP. Diversos fatores prognósticos pré-definidos foram testados por meio da regressão logística multivariada. RESULTADOS: Quatorze ensaios clínicos randomizados foram incluídos (2.095 pacientes). Houve 97 casos de CPP em 1.102 pacientes (8,8%) ventilados com a estratégia protetora e 148 casos em 993 pacientes (14,9%) ventilados com a estratégia convencional (risco ajustado relativo [RR], 0,64; 95% intervalo de confiança [IC], 0,46 - 0,88, p < 0,01). Houve 85 casos de CPP em 957 pacientes (8,9%) ventilados com volume corrente baixo e PEEP alto e 63 casos em 525 pacientes (12%) ventilados com volume corrente baixo e PEEP baixo (RR, 0,93; 95% CI, 0,64 - 1,37, p = 0,72). Foi encontrada uma relação de dose-resposta entre o aparecimento de CPP e o volume corrente (R2 por meio termo quadrático = 0,390), mas não entre o aparecimento de CPP e o nível de PEEP (R2 = 0,082). A manutenção de uma driving pressure inferior a 13 cmH2O durante a cirurgia está associado a menor incidência de síndrome do desconforto respiratório agudo (SDRA). CONCLUSÃO: Esta meta-análise de dados individuais suporta os efeitos benéficos da estratégia protetora de ventilação mecânica em pacientes submetidos à cirurgia e sugere que altos níveis de PEEP, na vigência de volume corrente baixo, não acrescentam benefícios
INTRODUCTION: Recent studies show that intraoperative mechanical ventilation using low tidal volumes can prevent postoperative pulmonary complications (PPC). The aim of this individual patient data meta-analysis is to evaluate the individual associations between tidal volume size and PEEP level, and occurrence of PPC. METHODS: Randomized controlled trials comparing protective ventilation and conventional ventilation in patients undergoing general surgery were screened for inclusion. The primary outcome was development of PPC. Predefined prognostic factors were tested using multivariate logistic regression. RESULTS: Fourteen randomized controlled trials were included (2095 patients). There were 97 cases of PPC in 1102 patients (8.8%) assigned to protective ventilation and 148 cases in 993 patients (14.9%) assigned to conventional ventilation (adjusted relative risk [RR], 0.64; 95% confidence interval [CI], 0.46 - 0.88; p < 0.01). There were 85 cases of PPC in 957 patients (8.9%) assigned to ventilation with low tidal volume and high PEEP levels and 63 cases in 525 patients (12%) assigned to ventilation with low tidal volume and low PEEP levels (RR, 0.93; 95% CI, 0.64 - 1.37; p = 0.72). A dose-response relationship was found between the appearance of PPC and tidal volume size (R2 for mean quadratic term = 0.390), but not between the appearance of PPC and PEEP level (R2 = 0.082). The maintenance of a driving pressure below 13 cmH2O during surgery is associated with reduced incidence of acute respiratory distress syndrome. CONCLUSION: This individual data meta-analysis supports the beneficial effects of protective ventilation settings in patients undergoing surgery and suggests no benefit from high PEEP levels with use of low tidal volume

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Spieth, Peter M., Andreas Güldner, Christopher Uhlig, Thomas Bluth, Thomas Kiss, Marcus J. Schultz, Paolo Pelosi, Thea Koch, and de Abreu Marcelo Gamba. "Variable versus conventional lung protective mechanical ventilation during open abdominal surgery." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-164891.

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Background: General anesthesia usually requires mechanical ventilation, which is traditionally accomplished with constant tidal volumes in volume- or pressure-controlled modes. Experimental studies suggest that the use of variable tidal volumes (variable ventilation) recruits lung tissue, improves pulmonary function and reduces systemic inflammatory response. However, it is currently not known whether patients undergoing open abdominal surgery might benefit from intraoperative variable ventilation. Methods/Design: The PROtective VARiable ventilation trial ('PROVAR') is a single center, randomized controlled trial enrolling 50 patients who are planning for open abdominal surgery expected to last longer than 3 hours. PROVAR compares conventional (non-variable) lung protective ventilation (CV) with variable lung protective ventilation (VV) regarding pulmonary function and inflammatory response. The primary endpoint of the study is the forced vital capacity on the first postoperative day. Secondary endpoints include further lung function tests, plasma cytokine levels, spatial distribution of ventilation assessed by means of electrical impedance tomography and postoperative pulmonary complications. Discussion: We hypothesize that VV improves lung function and reduces systemic inflammatory response compared to CV in patients receiving mechanical ventilation during general anesthesia for open abdominal surgery longer than 3 hours. PROVAR is the first randomized controlled trial aiming at intra- and postoperative effects of VV on lung function. This study may help to define the role of VV during general anesthesia requiring mechanical ventilation.

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Vladimir, Dolinaj. "Procena efikasnosti laringealne maske u odnosu na endotrahealni tubus u zbrinjavanju disajnog puta u dečjoj otorinolaringološkoj hirurgiji." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2017. https://www.cris.uns.ac.rs/record.jsf?recordId=104700&source=NDLTD&language=en.

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Uvod: Adenoidektomija sa tonzilektomijom je najčešće indikovana hirurška intervencija u dečjem uzrastu. Intervencija se izvodi u opštoj anesteziji. Endotrahealni tubus predstavlja „zlatni standard“ za obezbeđenje disajnog puta u dečjoj otorinolaringološkoj hirurgiji. Upotreba endotrahealnog tubusa nosi rizike od nastanka komplikacija koje se mogu javiti pri uvodu u opštu anesteziju, u toku hirurške intervencije i nakon ekstubacije deteta. Učestalost komplikacija se može smanjiti upotrebom supraglotičnih sredstava. Fleksibilna laringealna maska spada u prvu generaciju supraglotičnih sredstava, koja omogućava zadovoljavajuću oksigenaciju i ventilaciju bolesnika u ORL hirurgiji. Cilj istraživanja: Utvrditi: efikasnost fleksibilne laringealne maske u zaštiti disajnog puta od aspiracije krvi i sekreta gornjih disajnih puteva u odnosu na endotrahealni tubus u toku adenotonzilektomije; da li primena fleksibilne laringealne maske u zbrinjavanju disajnog puta u toku adenotonzilektomije utiče na učestalost postekstubacionih komplikacija u odnosu na zbrinjavanje disajnog puta endotrahealnim tubusom; da li zbrinjavanje disajnog puta fleksibilnom laringealnom maskom u toku adenotonzilektomije ima uticaj na intenzitet postoperativnog bola u odnosu na zbrinjavanje disajnog puta endotrahealnim tubusom; da li zbrinjavanje disajnog puta fleksibilnom laringealnom maskom u toku adenotonzilektomije ima uticaj na pojavu postoperativne mučnine i povraćanja u odnosu na zbrinjavanje disajnog puta endotrahealnim tubusom. Metodologija: Prospektivnom, randomizovanom, studijom bilo je obuhvaćeno 160 dečaka i devojčica uzrasta od 3 do 8 godina planiranih za elektivnu hiruršku intervenciju adenotonzilektomiju u opštoj anesteziji. Bolesnici su bili podeljeni u dve grupe: 80 bolesnika kod kojih je disajni put bio obezbeđen endotrahealnim tubusum (ET grupa) i 80 bolesnika kod kojih je disajni put bio obezbeđen laringealnom maskom (LMA grupa). Na kraju hirurške intervencije, u obe grupe bolesnika, izvršena je provera prisustva krvi na larinksu i u traheji pomoću fiberoptičkog bronhoskopa. Postekstubacione respiratorne komplikacije vezane za upotrebu fleksibilne laringealne maske odnosno endotrahealnog tubusa (kašalj, opstrukcija disajnog puta i laringospazam) bile su praćene neposredno nakon ekstubacije bolesnika. Procena postoperativnog bola bila je vršena pomoću Face, Legs, Activity, Cry, Consolability Scale 2 i 4 sata nakon hirurške intervencije kao i prvog postoperativnog dana u 7 sati ujutro. Postojanje postoperativne mučnine i povraćanja bilo je utvrđivano heteroanamnestički, anketom roditelja, dan nakon hirurške intervencije u 7 sati ujutro. Statistička analiza izvršena je pomoću statističkog paketa Statistical Package for Social Sciences – SPSS 21. Podaci su predstavljeni tabelarno i grafički, a statistička značajnost je određivana na nivou p<0.05. Rezultati: Ni kod jednog deteta iz ET odnosno LMA grupe bolesnika nakon hirurške intervencije fiberoptičkim bronhoskopom nije uočeno prisustvo krvi, sekreta niti regurgitiranog želudačnog sadržaja na larinksu odnosno u traheji. Bolesnici iz ET grupe su imali statistički značajno više komplikacija u odnosu na bolesnike iz LMA grupe (χ2=4.254; p=0.039; p < 0.05). Ne postoji statistički značajna razlika u distribuciji bolesnika sa i bez respiratornih komplikacija izmeĊu ET i LMA grupe (χ2=3.413; p=0.065; p > 0.05). U proceni postoperativnog bola FLACC skalom 2 sata nakon hirurške intervencije postoji statistički značajna razlika u intenzitetu postoperativnog bola kod bolesnika iz ET u odnosu na bolesnike iz LMA grupe (χ2=31.316; p=0.000; p<0.05). Četiri sata nakon hirurške intervencije, statistički je značajno više bolesnika sa umerenim bolom u ET grupi u odnosu na LMA grupu (χ2=40.705; p=0.000; p<0.05). Na dan otpusta, statistički je značajno više bolesnika sa blagim diskomforom u ET grupi bolesnika u odnosu na LMA grupu (χ2=8,012; p=0,005; p < 0.05). U LMA grupi bolesnika jedan ili 1.49% bolesnika je imao postoperativnu mučninu i povraćanje, dok je u ET grupi troje ili 3.56% bolesnika imalo postoperativnu mučninu i povraćanje. Zaključak: Fleksibilna laringealna maska pruža podjednaku zaštitu distalnih delova disajnog puta od krvi i sekreta tokom adenotonzilektomije kao i endotrahealni tubus. Učestalost postoperativnih komplikacija i intenzitet postoperativnog bola su manji kada se za obezbeđenje disajnog puta u toku adenotonzilektomije koristi fleksibilna laringealna maska. Primenom fleksibilne laringealne maske smanjuje se učestalost postoperativne mučnine i povraćanja u toku adenotonzilektomije.
Introduction: Adenoidectomy with tonsillectomy is the most indicated surgery in childhood. The intervention is performed under general anesthesia. Endotracheal tube represents the „gold standard“ for airway management in paediatric ENT surgery. The use of endotracheal tube carries the risk of complications that may occur during the induction of general anesthesia, during the surgery and after extubation of the child. The frequency of complications may be reduced by the use of supraglottic airway devices. Flexible laryngeal mask is first generation of supraglottic airway devices, which allows sufficient oxygenation and ventilation of patients in ENT surgery. Aims: To determine the effectiveness of the flexible laryngeal mask which protectes the airway from aspiration of blood and secretions of the upper airways compared to the airway management with endotracheal tube during adenotonsillectomy; to determine does the usage of the flexible laryngeal mask in airway management during adenotonsillectomy affects the frequency of post extubation complications compared to the airway management with endotracheal tube, as wll as does the usage of the flexible laryngeal mask in airway management during adenotonsillectomy has an impact on the intensity of postoperative pain compared to the airway management with endotracheal tube, and does the usage of the flexible laryngeal mask in airway management during adenotonsillectomy has an impact on the incidence of postoperative nausea and vomiting compared to the airway management with endotracheal tube. Methodology: One hundred and sixty boys and girls aged from 3 to 8 years scheduled for elective surgical intervention adenotnosillectomy in general anaesthesia were included in this prospective, randomized study. Patients were divided into two groups: 80 patients in whom the airway was managed with a cuffed endotracheal tube (ET group) and 80 patients in whom airway was managed with a laryngeal mask (LMA group). At the end of surgical procedure, in both groups of patients, fiberoptic bronchoscopy was performed to verify the presence of blood in the larynx and trachea. Immediate respiratory complications associated with the use of flexible laryngeal mask or endotracheal tube (cough, airway obstruction and laryngospasm) were monitored following extubation of patients. Postoperative pain assessment was performed using Face, Legs, Activity, Cry, Consolability Scale 2 and 4 hours following surgery as well as the first postoperative day at 7 o'clock a.m. The presence of postoperative nausea and vomiting was confirmed heteroanamnestically by polling the parents the day after surgery at 7 o'clock a.m. The statistical analysis was performed using Statistical Package for Social Sciences - SPSS version 21. The data were presented in tables and graphs, statystical significance was set at p value of less than 0.05. Results: Following surgery there were no any patient in ET or LMA group in which the presence of blood, secretion or regurgitated stomach contents on larynx or in the trachea could be observed by using the fiberoptic bronchoscope. Patients in the ET group had statistically more significant complications compared to patients in the LMA group (χ2 = 4.254; p = 0.039; p <0.05). There is no statistically significant difference in the distribution of patients with and without respiratory complications between ET and LMA groups (χ2 = 3.413; p = 0.065; p> 0.05). In the assessment of postoperative pain using FLACC scale 2 hours following surgical intervention, there is a statistically significant difference in the intensity of postoperative pain in ET patients compared to patients in the LMA group (χ2 = 31.316, p = 0.000, p <0.05). Four hours following surgical intervention, a statistically significant number of patients had mild pain in the ET group compared to the LMA group (χ2 = 40.705; p = 0.000; p <0.05). On the day of release, statistically significant numbers of patients with mild discomfort in the ET group were compared to the LMA group (χ2 = 8,012; p = 0,005; p <0.05). In the LMA group, one or 1.49% of the patients had postoperative nausea and vomiting, while in the ET group, three or 3.56% of the patients had postoperative nausea and vomiting. Conclusion: Flexible laryngeal mask provides equal protection of the distal parts of airway from the blood and secretions during adenotonsillectomy as the endotracheal tube. The frequency of postoperative complications and the intensity of postoperative pain are smaller when a flexible laryngeal mask is used for airway management during adenotonsillectomy. The usage of the flexible laryngeal mask reduces the frequency of postoperative nausea and vomiting during adenotonsillectomy.

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QUEMENER, CLAIRE. "L'analgesie peridurale thoracique peut-elle aider a prevenir les complications respiratoires apres chirurgie pour cancer de l'oesophage ?" Rennes 1, 1992. http://www.theses.fr/1992REN1M154.

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Gros, Thierry. "Les accidents anaphylactoi͏̈des per opératoires : analyse de 374 bilans réalisés dans le cadre de la consultation d'allergo-anesthésie du C.H.U. Montpellier (1991-1994)." Montpellier 1, 1995. http://www.theses.fr/1995MON11160.

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VILLELA, Ana Carolina Vasques. "Anestesia epidural toracolombar com lidocaína a 2% ou lidocaína hiperbárica a 5% pelo uso de cateter epidural totalmente implantado em cães." Universidade Federal de Goiás, 2012. http://repositorio.bc.ufg.br/tede/handle/tde/886.

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Made available in DSpace on 2014-07-29T15:07:41Z (GMT). No. of bitstreams: 1 Dissertacao Ana Carolina Vasques Villela.pdf: 1200187 bytes, checksum: e80340dfd98ca2e1e517f50dcd0bef34 (MD5) Previous issue date: 2012-02-24
A anestesia local se popularizou na medicina veterinária no século XX, mas alguns de seus recursos, como o cateter epidural e as soluções hiperbáricas, bastante utilizados no homem atualmente ainda são pouco estudados e aplicados em animais. Em seguida, outro estudo verificou a qualidade da anestesia epidural toracolombar com lidocaína a 2% ou hiperbárica a 5% e a influência do decúbito e o do tempo de permanência do cateter epidural na qualidade deste bloqueio. Para isso foram usados sete cães machos, adultos, pesando 12,76 +/-2,59 kh. Com os animais até o espaço T13-L1, tendo seu dispositivo sepultado no tecido subcutâneo. Em seguida, administrou-se 4 mg/kg de lidocaína isobárica a 2% com os animais em posição quadrupedal(IQ4) ou em decúbito lateral (IL4); 3 mg/kg de lidocaína hiperbárica a 5% em posição quadrupedal (HQ3) ou em decúbito lateral (HL3); e 4 mg/kg de lidocaína hiperbárica a 5% em posição quadupedal (HQ4) ou em decúbito lateral (HL4). Foram avaliadas a viabilidade da técnica de implantação; a ocorrência de complicações após a implantação ou retirada do cateter epidural; o tempo de permanência do cateter epidural; os efeitos da administração de lidocaína a 2% ou hiperbárica a 5% sobre a FC, , PAS, SPO2 e TR; a a qualidade do bloqueio anestésico (latência, extensão, simetria e duração do bloqueio anestésico); influência do decúbito e do tempo de permanência do cateter na qualidade do bloqueio anestésico. A implantação do cateter epidural foi viável e isenta de complicações; houve redução significativa somente nos valores de e TR em relação ao valor basal nos grupos IQ4, IL4, HQ3, HL3,HQ4. Não foram observadas diferenças significativas na FC, PAS, SPO2, latência, duração e extensão do bloqueio entre os grupos. O decúbito não influenciou significativamente a qualidade do bloqueio. O tempo de permanência do cateter no espaço epidural influenciou significativamente a duração máxima do bloqueio sensitivo. Em conclusão, o modelo descrito para implantação do cateter epidural é viável, porém o tempo que o cateter permaneceu no espaço epidural influenciou a duração do bloqueio anestésico e a lidocaína hiperbárica a 5% não mostrou vantagens em relação ao uso da lidocaína isobárica a 2% na anestesia epidural toracolombar.

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Spieth, Peter M., Andreas Güldner, Christopher Uhlig, Thomas Bluth, Thomas Kiss, Marcus J. Schultz, Paolo Pelosi, Thea Koch, and de Abreu Marcelo Gamba. "Variable versus conventional lung protective mechanical ventilation during open abdominal surgery: study protocol for a randomized controlled trial." BioMed Central, 2014. https://tud.qucosa.de/id/qucosa%3A28659.

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Background: General anesthesia usually requires mechanical ventilation, which is traditionally accomplished with constant tidal volumes in volume- or pressure-controlled modes. Experimental studies suggest that the use of variable tidal volumes (variable ventilation) recruits lung tissue, improves pulmonary function and reduces systemic inflammatory response. However, it is currently not known whether patients undergoing open abdominal surgery might benefit from intraoperative variable ventilation. Methods/Design: The PROtective VARiable ventilation trial ('PROVAR') is a single center, randomized controlled trial enrolling 50 patients who are planning for open abdominal surgery expected to last longer than 3 hours. PROVAR compares conventional (non-variable) lung protective ventilation (CV) with variable lung protective ventilation (VV) regarding pulmonary function and inflammatory response. The primary endpoint of the study is the forced vital capacity on the first postoperative day. Secondary endpoints include further lung function tests, plasma cytokine levels, spatial distribution of ventilation assessed by means of electrical impedance tomography and postoperative pulmonary complications. Discussion: We hypothesize that VV improves lung function and reduces systemic inflammatory response compared to CV in patients receiving mechanical ventilation during general anesthesia for open abdominal surgery longer than 3 hours. PROVAR is the first randomized controlled trial aiming at intra- and postoperative effects of VV on lung function. This study may help to define the role of VV during general anesthesia requiring mechanical ventilation.

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Verin, Catherine. "Anesthésie pour circoncision de l'enfant, bloc pénien versus caudale : confort chirurgical, analgésie, complications." Montpellier 1, 1998. http://www.theses.fr/1998MON11081.

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Hirota, Adriana Sayuri. "Análise do suporte ventilatório mecânico durante anestesia e sua correlação com as complicações pulmonares pós-operatórias: um estudo observacional." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-02102014-111242/.

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Introdução: A formação de atelectasia durante a indução anestésica pode ser um dos fatores responsáveis pela ocorrência de complicações pulmonares pós-operatórias (CPP). A aplicação de pressão positiva expiratória ao final da expiração (PEEP), uso criterioso de altas frações inspiradas de oxigênio e a utilização de manobras de recrutamento alveolar no período intra-operatório são recursos utilizados para a prevenção de atelectasia em procedimentos anestésicos. O objetivo deste estudo foi avaliar o modelo de ventilação mecânica adotado em procedimentos anestésicos de longa duração e suas correlações com as complicações pulmonares pós-operatórias. Métodos: Foram avaliadas em estudo observacional as cirurgias com mais de cinco horas de duração. No início do procedimento anestésico, na sala de cirurgia e após o seu término, na unidade de terapia intensiva, os parâmetros ventilatórios utilizados foram anotados e correlacionados com os achados das radiografias torácicas e saturação periférica de oxigênio (SpO2) em ar ambiente. Resultados: Cento e vinte e um pacientes foram observados. O tempo total de anestesia 499,4 ± 159,8 minutos. O volume corrente (VC) determinado no período intraoperatório foi 8,09 ± 2,15 mL/kg e a PEEP utilizada de 3,05 ± 2,31 cmH2O. Houve diferença para a mediana da SpO2 em ar ambiente (96% [95-97] vs 95% [92-96], p <0,001) comparando os períodos pré e pós-operatório. A freqüência de pacientes que apresentaram atelectasia nas radiografias de tórax do período pós-operatório (38,8%) foi significantemente maior que a do período pré-operatório (0%), x2=32,259. Não foi encontrado correlação entre os achados e o tempo de anestesia (p=0,708); a PEEP intra-operatória (p=0,296); tempo de permanência com suporte ventilatório mecânico no pósoperatório (p = 0,146) e tabagismo (p = 0,563). Conclusões: No período intra-operatório o PEEP utilizado em procedimentos de longa duração é baixo. Ocorre queda na SpO2 e aumento na incidência de atelectasia no período pós-operatório em comparação com o pré-operatório. São necessários outros estudos para melhor avaliação dos fatores responsáveis
Introduction: The formation of the atelectasis during the induction of the anesthesia can be one of the factors involved in the occurrence of postoperative pulmonary complications (PPCs). The application of the positive end-expiratory pressure (PEEP), low inpiratory concentrations of oxygen and the alveolar recruitment maneuvers perform in the intraoperative period are approaches used in the prevention of atelectasis in the anesthesia procedures. The objective of this study was to evaluate, in prospective observational study, the pattern of mechanical ventilatory assistence during longer anesthesia procedures and its correlations with the PPCs. Methods: The surgeries procedures longer than five hours have been evaluated in observational study. At the beginning of the anesthesia procedure, in the operatory room and after its terminus, in the intensive care unit, the mechanical ventilation parameters were determined and correlated with the findings in the chest x-rays and peripheral oxygen saturation (SpO2) in room air. Results: One hundred twenty one patients have been observed. The total time of anesthesia was 499,4 ± 159,8 minutes. The tidal volume (VT) in the intraoperative period was 8,09 ± 2,15 mL/kg and the PEEP used was 3,05 ± 2,31 cmH2O. There was a difference for the median of the SpO2 in room air (96% [95-97] vs 95% [92-96], p <0,001) comparing the pre and postoperative periods. The frequency of patients who had presented atelectasis in the chest x-rays of the postoperative period (38,8%) was significantly higher than the preoperative period (0%), x2=32,259. No correlation was found among these findings and the anesthesia time (p=0,708); the intraoperative PEEP used (p=0,296); time with mechanical ventilatory support in the postoperative period (p = 0,146) and smoking habits (p = 0,563). Conclusions: In the intraoperative period, the PEEP is low in longer procedures. The SpO2 decreases and the incidence of the atelectasis increases in the postoperative period, when compared with the preoperative one. Other researches are required for better evaluation of the factors related for the development of the PPCs

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Dong, Siwei. "Réactions d'hypersensibilité immédiate en anesthésie : épidémiologie et risques environnementaux." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0171/document.

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Les réactions d'hypersensibilité immédiate survenant au cours de l'anesthésie demeurent un sujet de préoccupation majeure pour les anesthésistes. Le médicament le plus fréquemment responsable d'une anaphylaxie sont les curares. Le but de ce travail est de préciser l'épidémiologie actuelle et d'identifier certains facteurs environnementaux susceptibles d'expliquer la fréquence élevée des réactions allergiques aux curares qui peuvent survenir en l'absence de toute exposition préalable. Dans la première partie de la thèse, une enquête nationale décrivant l'épidémiologie des réactions anaphylactiques peranesthésiques entre 2005 et 2007 en France. Elle a confirmé l'intérêt du dosage d'IgE spécifique anti-curare. La survenue de réactions d'hypersensibilité immédiate allergique à l'induction anesthésique lors d'une première exposition aux curares a conduit à évoquer l'existence d'une sensibilisation croisée avec des substances présentes dans l'environnement et possédant un ammonium quaternaire. Différentes hypothèses ont été proposées, notamment une exposition aux produits cosmétiques et/ou désinfectants, une exposition à des antigènes de type phosphorylcholine rencontrés dans les levures, ou certains parasites. Dans la deuxième partie de la thèse, deux populations professionnelles, des apprentis coiffeurs exposés à des agents chimiques contenant des ions ammoniums, et des boulanger-pâtissiers exposés à des allergènes de levures et de parasites, ont été comparées avec la population générale à la recherche de différences concernant la prévalence des anticorps IgE spécifique anti-curare. Au terme de ce travail, l'exposition à des produits cosmétiques chez les coiffeurs apparaît comme un facteur de risque de développer des anticorps IgE spécifique anti-curare, démontrant pour la première fois l'hypothèse du lien entre l'exposition répétée aux produits cosmétiques contenant l'ammonium quaternaire et la sensibilisation croisée aux curares
Immediate hypersensitivity reactions occurring during anesthesia remains a major concern for anesthesiologists. The drugs most frequently responsible for anaphylaxis are neuromuscular blocking agents (NMBAs). The purpose of this study is to determine the current epidemiology and to identify environmental factors that may explain the high frequency of allergic reactions to neuromuscular blocking agents that can occur without any prior exposure. In the first part of the thesis, a national survey describing the epidemiology of anaphylaxis during anesthesia between 2005 and 2007 in France was carried out. The value of testing specific IgE against NMBA was confirmed.The occurrence of immediate allergic hypersensitivity reaction when first exposure to an NMBA during induction led to evoke the existence of cross-sensitization with substances present in environment and having a quaternary ammonium compound. Different hypotheses have been proposed including exposure to cosmetics and / or disinfectants, exposure to antigens encountered in phosphorylcholine yeasts, or parasites, or exposure to a derivative opiate, pholcodine. In the second part of the thesis, two occupational populations, hairdressers apprentice exposed to chemical agents containing ammonium ions, baker and pastry maker exposed to allergens yeast and parasites were compared with the general population to search for differences regarding the prevalence of specific IgE antibody against NMBA. At the end of this work, hairdressers exposed to cosmetics agents appears to be a risk factor for developing specific IgE antibodies against NMBA and we demonstrated for the first time the hypothesis of the ross-sensitization between repeated exposures to cosmetics products containing quaternary ammonium and NMBAs

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Durieux, M. E. "Grensincidenten Modulating the injury response /." Maastricht : Maastricht : Maastricht University ; University Library, Maastricht University [Host], 2001. http://arno.unimaas.nl/show.cgi?fid=12698.

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Marié, Sophie. "Analgésie après chirurgie du pied : efficacité et complications du bloc du nerf sciatique avec mise en place d'un cathéter poplite." Bordeaux 2, 2000. http://www.theses.fr/2000BOR23023.

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Bussat, Sophie. "Qualité de récupération psychomotrice après une coloscopie sous anesthésie générale : intérêt des tests de réveil." Bordeaux 2, 1994. http://www.theses.fr/1994BOR2M046.

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Euzen, Violaine. "Exploration des accidents per-anesthésiques d'allure allergique : bilan de l'expérience de l'unité des maladies allergiques de l'hôpital Pellegrin portant sur 53 patients." Bordeaux 2, 1997. http://www.theses.fr/1997BOR2M089.

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Heriot, Jody L. "Implementation of a Beta Blocker Protocol." UNF Digital Commons, 2012. http://digitalcommons.unf.edu/etd/415.

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Background: Beta blockers are recommended by the American College of Cardiology/American Heart Association Guidelines for high and intermediate-risk cardiac patients undergoing non-cardiac surgery. Beta blockers are a class of drugs that moderate the effects of increased catecholamine levels on the heart by selectively blocking beta receptors in the heart and blood vessels, resulting in a lower heart rate and blood pressure. Beta blocker use perioperatively has been shown to reduce the risk of ischemia and infarction. Purpose: The purpose of this project is to address beta blocker use in a group of anesthesia providers who routinely attend to high-risk and intermediate-risk cardiac patients undergoing non-cardiac surgery in a medium-sized private hospital in suburban South Florida. There are barriers to the implementation of the published guidelines for beta blocker administration, including lack of awareness of the best current practice and a lack of a formal beta blocker protocol at the institutional level. Methods: A simple and inexpensive beta blocker protocol was implemented and evaluated by various means. Beta blocker administration practices were examined and documented prior to and after protocol implementation. Beta blocker usage was examined prior to and after protocol implementation Findings/Implications: It was hypothesized that increased anesthesia provider awareness would lead to increased administration of perioperative beta blockers to high-risk and intermediate-risk cardiac patients undergoing non-cardiac procedures. Although there was a knowledge increase related to the new beta blocker protocol, no change in practice was observed.

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Pinto, Xavier. "Potentiels évoqués somesthésiques et anesthésie totale intraveineuse sous propofol : comparaison des effets de l'alfentanil et du sufentanil sur les potentiels évoqués du nerf tibial postérieur." Bordeaux 2, 1996. http://www.theses.fr/1996BOR23011.

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Dahlstrand, Ursula. "Femoral and Inguinal Hernia : How to Minimize Adverse Outcomes Following Repair." Doctoral thesis, Uppsala universitet, Kolorektalkirurgi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-162203.

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Groin hernia is common, and each year 200 repairs per 100 000 adult inhabitants are performed in Sweden. Groin hernias are either inguinal or femoral (2-4%). Elective repair is not associated with an excess mortality, but adverse outcomes include recurrence and long-term pain. Emergency procedures have a 4% mortality rate with an increased risk for bowel resection and postoperative complications. The aim of this thesis was to identify risk factors for adverse outcomes and to propose measures to improve groin hernia treatment. Twenty-three per cent of female hernias were femoral. Thirty-six per cent of femoral hernias, and 5% of inguinal hernias, have emergency procedures. Females (OR 1.47) and patients above 65 years-of-age (OR 2.24) were at higher risk for emergency repair. Bowel resection was performed in 23% of emergency femoral repairs, and the 30-day mortality was 10 times that of an age- and gender-matched population. The majority of emergency patients were unaware of their hernia, and one third had previously had no groin symptoms. Femoral repairs were at larger risk for recurrence than inguinal repairs. The surgical techniques with least risk for recurrence were preperitoneal mesh repairs (open HR 0.28, and laparoscopic HR 0.31). Long-term pain was present in 24% of femoral hernia patients, of whom 5.5% described pain interfering with daily activities. The only factor predicting the risk for long-term pain was pain preoperatively. Pain decreased with time. In a randomized study on inguinal hernia, TEP resulted in less pain six weeks after surgery than Lichtenstein repair performed under local anesthesia (LLA). TEP patients were to a larger extent able to perform sporting activities. No difference was seen in intra-operative complications. Femoral hernias should be given high priority for repair and preperitoneal techniques should be used. Earlier diagnosis, in the elective setting, is probably difficult to attain. Heightened awareness in the emergency department is required. TEP is safe, and results in less pain than LLA six weeks after surgery. A widening of indications for TEP in primary inguinal hernia repair is justifiable.

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Mutter, Thomas Charles. "Serious postoperative cardiovascular and respiratory complications in obstructive sleep apnea patients: matched cohort analysis of clinical and administrative data." 2012. http://hdl.handle.net/1993/8114.

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Problem: The risk of serious postoperative cardiovascular and respiratory complications (SPCRCs) in patients with obstructive sleep apnea (OSA) is poorly defined. Methods: In this cohort study (n = 21221), patients with clinically diagnosed OSA were matched to controls without OSA to compare the risk of postoperative death and SPCRCs in an administrative database. Results: Compared to non-OSA controls, OSA patients were at increased risk of postoperative respiratory failure both before and after diagnosis with OSA. Prior to diagnosis, OSA patients, particularly those with severe OSA, were also at increased risk of cardiac arrest and SPCRCs . After diagnosis with OSA, except for postoperative respiratory failure, the risk of SPCRC’s was not different from controls. Also, the risk of postoperative death among OSA patients after diagnosis was not different from controls. Other important predictors of SPCRCs and death included admission in an intensive care unit at the time of surgery, a history of congestive heart failure, a higher Charlson comorbidity index score and the type of surgery. Conclusions: OSA was associated with an increased risk of SPCRCs, especially prior to diagnosis and in severe disease. This suggests that screening for and treating OSA in preoperative patients would reduce the risk of SPCRCs. However, the significant influences of the type of surgery and the presence of medical comorbidities on the risks of SPCRCs and death, regardless of the presence of OSA, must be considered in planning efficient and equitable interventions to reduce these risks.

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Foster, Paul Stephen. "Skeletal muscle malignant hyperpyrexia." Phd thesis, 1987. http://hdl.handle.net/1885/142452.

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Sharma, Vandna. "Study of Peri-operative Complications in Persons with Disabilties under Dental Treatment under General Anesthesia at the Mount Sinai Hospital." Thesis, 2011. http://hdl.handle.net/1807/31438.

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This was a two part study. Part one was a retrospective chart review to ascertain the prevalence and predictors of peri-operative complications in PWD receiving their dental care under general anesthesia (GA). Part two was a prospective survey of parents/caregivers regarding their satisfaction with the service as well as to ascertain the prevalence of post-operative symptoms incurred by patients. In Part 1, the prevalence of complications in PWD was 4 times higher than the 6% stated in the literature for the general population. Time under GA, and no previous history of dental care under GA were significantly related to complications. In Part 2, 100% of patients experienced post-operative symptoms; nonetheless, 92.7% of parents/caregivers were satisfied with the service provided. There prevalence of complications in the PWD in this study was high. Prior to treatment under GA, adequate pre-operative medical evaluations must be completed and time under GA minimized.

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"Aortocaval compression at term pregnancy." Thesis, 2008. http://library.cuhk.edu.hk/record=b6074593.

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Although ACC exerted a strong effect on the haemodynamic changes after SA, SA per se did not have much influence on ACC. The incidence and severity of ACC remained unchanged compared with the pre-spinal state. As long as maternal blood pressure were well controlled, the uterine blood flow indices were not affected by ACC.
Although there are many publications on ACC, most publications have considered ACC as a single entity, or reported its effects in terms of just a few end-point measures. The information published so far on ACC remains fragmented. This will be readdressed by taking a multidisciplinary approach with input from the fields of anaesthesia, obstetrics and radiology to non-invasively assess the haemodynamic changes associated with ACC.
Aortocaval compression occurs when parturients lie in the supine position with the gravid uterus compressing the aorta and the inferior vena cava. This interferes with venous return to the heart to reduce cardiac output, resulting in hypotension, uterine hypo-perfusion and fetal acidosis. Under neuraxial anaesthesia when the compensatory mechanisms via the sympathetic nervous outflow are blocked, the effects from ACC are exaggerated and results in maternal and fetal morbidity.
Intermittent IVC compression was responsible for most of the haemodynamic effects, presenting mainly as a reduction in cardiac output. Blood pressure or heart rate changes are poor indicators for IVC compression, and most patients were asymptomatic. Patients who have moderate to severe ACC have a higher incidence of hypotension after SA and consume a higher amount of phenylephrine for maintaining BP.
The research was conducted on non-labouring term parturients presenting for elective Caesarean section under spinal anaesthesia. Measurements were performed to assess the patency of blood vessels and haemodynamic responses to lateral tilts, using ultrasound and non-invasive haemodynamic monitors.
This research has achieved the following: (1) Qualitative measurements of compression of the aorta and IVC with US imaging and Doppler US; (2) Development of a new simple bedside method for detecting ACC using US; (3) Quantitative measurements of physiological responses in the maternal and fetal circulation associated with ACC; (4) Investigation of the effects of spinal anaesthesia per se on ACC.
Lee, Wee Yee Shara.
Adviser: Khaw Kim Sun.
Source: Dissertation Abstracts International, Volume: 70-06, Section: B, page: 3446.
Thesis (Ph.D.)--Chinese University of Hong Kong, 2008.
Includes bibliographical references (leaves 234-254).
Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.
Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web.
Abstracts in English and Chinese.
School code: 1307.

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Ulrici, Johanna. "Atemwegsassozierte Komplikationen bei übergewichtigen und adipösen Kindern in der Anästhesie." Doctoral thesis, 2011. https://ul.qucosa.de/id/qucosa%3A11398.

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Übergewicht und Adipositas im Kindes- und Jugendalter sind Gesundheitsprobleme, die auch auf dem Gebiet der Anästhesie zunehmend relevant werden. In der vorliegenden Dissertationsschrift wurde untersucht, inwiefern übergewichtige Kinder und Jugendliche, im Vergleich zu nicht-übergewichtigen, Komplikationen des Atemwegsmanagementes und der Oxygenierung während einer Allgemeinanästhesie aufweisen und welche Bedeutung die Thematik in der deutschen Population für die Kinderanästhesie hat. Mit Hilfe spezieller Erfassungsbögen wurden folgende Parameter ermittelt und die übergewichtigen mit den nicht-übergewichtigen Studienteilnehmern verglichen: der Mallampati Score, schwierige Maskenventilation und Intubation, die Verwendung eines Atemwegshilfsmittels, der Cormack-Lehane Score und die Anzahl der Intubationsversuche. Daneben wurde die Inzidenz von Atemwegsobstruktionen (Broncho- und Laryngospasmen), Husten als Zeichen der Atemwegsirritation und Sauerstoffsättigungsabfälle um mehr als 10 % des Ausgangswertes erfasst. Es zeigte sich ein signifikant höherer Mallampati Score und ein signifikant häufigeres Auftreten von Husten (p < 0,05). Alle weiteren Parameter blieben ohne statistisch relevanten Unterschied, obwohl Atemwegshilfsmittel prozentual häufiger bei Übergewichtigen eingesetzt wurden. Bei einer gesonderten Analyse der in die Studie eingeschlossenen Untergewichtigen zeigte sich eine überraschend gehäufte Inzidenz hinsichtlich der schwierigen Laryngoskopie und einer Reintubation. Die verschiedenen Ursachen für die vorliegenden Ergebnisse werden in der Promotionsschrift detailliert diskutiert. Es wird insgesamt deutlich, dass nicht alleine Übergewicht und Adipositas ausschlaggebend für Atemwegskomplikationen sind, aber durchaus einen Risikofaktor darstellen. Darüber hinaus scheinen auch untergewichtige Kinder ein erhöhtes Risiko für Atemwegskomplikationen zu habe.

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Ortega, Audrey Marie Caroline. "Incidentes, acidentes e complicações da anestesia local na prática odontológica." Master's thesis, 2018. http://hdl.handle.net/10284/6917.

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A prática cirúrgica dentária geralmente requer a prática da anestesia. A anestesia dental é uma prática muito comum para dentistas. Esta anestesia deve ser de excelente qualidade para garantir boas práticas de cuidados, bem como conforto e segurança para o paciente. Este ato, no entanto, não está sem risco. Pode haver diferentes complicações. Nesta tese, nosso objetivo é realizar uma revisão da literatura, identificar claramente os vários tipos de acidentes identificados durante a anestesia dental, suas causas, sua prevenção e seu gerenciamento. Material e método: pesquisa bibliográfica em bases de dados eletrônicos médicos (PUBMED, B-ON, Science direct, PMC), utilizando palavras-chave: anestesia local - técnicas de anestesia dental - acidentes de anestesia dental - manejo de acidentes de anestesia dental – complicações anestesia. Critérios para inclusão: artigos completos (excluindo o título abstrato ou único) respondendo palavras-chave em combinações, revisões e trabalhos listados em sites de referência (pubmed, science direct), em língua português, inglês, e francês com um intervalo de tempo entre 1995-2018.
Dental surgical practice usually requires the practice of anesthesia. Dental anesthesia is a very common practice for dentists. This anesthesia should be of excellent quality to ensure good care practices as well as comfort and safety for the patient. This act, however, is not without risk. There may be different complications. In this thesis, our objective is to carry out a review of the literature, to clearly identify the various types of accidents identified during dental anesthesia, their causes, their prevention and their management. Material and methods: bibliographic research in medical electronic databases (PUBMED, B-ON, Science direct, PMC) using keywords: local anesthesia - dental anesthesia techniques - dental anesthesia accidents - dental anesthesia accident management - complications anesthesia. Criteria for inclusion: complete articles (excluding abstract or single title) by answering keywords in combinations, reviews and works listed on reference sites (pubmed, science direct), in Portuguese, English, and French language with a time interval between 1995-2018.

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Botelho, Marco Manuel. "Transplante renal heterotópico: técnica cirúrgica." Master's thesis, 2015. http://hdl.handle.net/10316/30567.

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Trabalho final de mestrado integrado em Medicina, apresentado à Faculdade de Medicina da Universidade de Coimbra.
A implementação do transplante como terapêutica curativa, permitiu alcançar um patamar de cuidados que visam manter uma elevada qualidade e expectativa de vida. Daí decorre o objectivo deste artigo, que passa por sequenciar os procedimentos inerentes à técnica cirúrgica e às suas especificidades. A pesquisa bibliográfica teve como fontes essenciais a base de dados do Pubmed e os livros das bibliotecas do Serviço de Urologia do Centro Hospitalar e Universitário de Coimbra e do Pólo das Ciências da Saúde da Universidade de Coimbra. Daqui advieram 22 fontes bibliográficas. A abordagem de qualquer tema fica enriquecida pela percepção histórica e evolutiva do mesmo, para que consigamos enquadrar as melhorias e metas atingidas ao longo dos anos, como pontos fundamentais para os conhecimentos dos dias de hoje. Motivo pelo qual, o contributo de diversos nomes da transplantação renal como Voronoy, René Kuss, Joseph Murray ou Sir Peter Medawar, entre outros, tenham um papel de relevo no processo evolutivo desta técnica. Na preparação para a cirurgia, a avaliação geral e completa do doente é imperativa. Para assegurar as condições ideais ao procedimento, é importante avaliar os parâmetros vitais, equilíbrio hidroelectrolítico e condições electromorfológicas da função cardiorrespiratória. A terapia imunossupressora, que estes processos necessitam, deve ser criteriosamente escolhida para que a sobrevida do enxerto e do doente sejam exponenciadas. A preparação cuidada do doente e o seu posicionamento na mesa operatória é importante para uma abordagem local correcta. Após a preparação do enxerto, é necessário escolher qual a abordagem anastomótica a ser usada, tanto a nível vascular como a nível urinário. Tendo em conta essa questão, a pesquisa bibliográfica efectuada permitiu concluir que as variantes técnicas desta cirurgia são afectadas, não só pela consideração das vantagens e desvantagens de cada uma, mas também pela experiência técnica do cirurgião e pelas variações anatómicas do doente e do próprio enxerto. Enquanto a nível de anastomoses vasculares as variações anatómicas ditam a escolha, a nível da reconstrução do tracto urinário a escolha baseia-se nas vantagens de cada tipo de técnica cirúrgica. Assim, neste parâmetro, as mais vantajosas e frequentemente aceites são os diversos tipos de ureteroneocistostomia, que permitem uma maior fiabilidade e uma menor probabilidade de complicações. O procedimento cirúrgico pode apresentar diversas complicações. Entre elas destacam-se as estenoses, as hemorragias, as fístulas urinárias e as reacções de rejeição. Por estas possíveis ocorrências, o manuseamento cuidado do enxerto e escolhas fundamentadas são fulcrais para uma minimização de riscos. Uma referência importante, são as pequenas especificidades inerentes aos casos em que os dadores ou receptores são crianças. Este facto leva a que as técnicas sofram pequenos ajustes, de forma a serem adaptadas à situação. Se relativamente à anastomose urinária esta se processa como nos adultos, nas vasculares, existem variações como o recurso a patch de Carrel ou a transplante em bloco, devido às divergências de calibres, entre os vasos do dador e do receptor. Em qualquer dos casos, os cuidados pós cirúrgicos são fundamentais para uma preservação da função renal e a diminuição da ocorrência de complicações precoces e tardias.

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Geibel, Stephan. "Vergleich von Anästhesieverfahren bei chirurgischen Eingriffen an der oberen Extremität." Doctoral thesis, 2017. http://hdl.handle.net/11858/00-1735-0000-0023-3EC6-2.

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Benchimol, Maxime. "Complicações pós e intra-operatórias na anestesia de bloqueio regional do nervo alveolar inferior." Master's thesis, 2021. http://hdl.handle.net/10284/9644.

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Introdução: Esta revisão narrativa examina artigos de particular interesse sobre o tema: complicações anestésicas do nervo alveolar inferior. Objetivos: O objetivo desta revisão narrativa é determinar o que pode levar a complicações anestésicas do nervo alveolar inferior, o seu tratamento e prevenção. Materiais e Métodos: As buscas foram realizadas nos websites SCIELO, B-ON e PUB MED, utilizando as seguintes palavras-chave: "anasthesia, complications alveolar inferior”, com o objetivo de angariar e debater o máximo de informação sobre este tema. Resultados e Conclusões: Os resultados obtidos revelam a importância de reconhecer a anatomia do nervo alveolar inferior e sua envolvência, do tipo de técnicas anestésicas e material utilizável sendo assim capaz de diminuir a probabilidade de erros e complicações intra e pós anestésicas. Devendo também reconhecer estas complicações caso ocorram e como as solucionar.
Introduction: This narrative review examines articles of particular interest for anesthetic complications of the lower aleveolar nerve. Objectives: The objective of this narrative review is to determine how to approach anesthetic complications of the lower aleveolar nerve, treatment, prevention. Materials and Methods: The searches were carried out on the websites SCIELO, B-ON and PUB MED, using the following keywords: "anasthesia,lower alveolar complications", in order to gather and discuss as much information as possible on this topic. Results and Conclusions: The results obtained reveal the importance of recognizing the anatomy of the lower alveolar nerve and its involvement, the type of anesthetic techniques and material that can be used, thus being able to reduce the probability of intra- and post-anesthetic errors and complications. It should also recognize these complications if they occur and how to solve them.

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Tinoco, Catarina Sousa Laranjo. "Anesthetic management of endovascular treatment for acute ischemic stroke: influences on outcome and complications." Master's thesis, 2017. https://repositorio-aberto.up.pt/handle/10216/104444.

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Tinoco, Catarina Sousa Laranjo. "Anesthetic management of endovascular treatment for acute ischemic stroke: influences on outcome and complications." Dissertação, 2017. https://repositorio-aberto.up.pt/handle/10216/104444.

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Chen, Ling-Ling, and 陳鈴鈴. "The Effect of Inhalation versus Total Intravenous Anesthesia on Fluid Management and Complication during Free Flap Surgery." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/89423d.

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碩士
中臺科技大學
醫療暨健康產業管理系碩士班
103
Abstract Backgrounds and Purpose: There has been a substantial increase of head and neck cancer patients in Taiwan over past few years. Free flap reconstruction has become a mainstream surgery for prolonging patient’s life and enhancing the quality of medical prognosis. One of the most important roles in time consuming surgery is an anesthetic technique that stabilizes hemodynamics during operation and reduces the complications after surgery. This study is primarily concerned with the infusion volumes of surgery and post-operative complications at different methods of anesthesia for free flap surgery. Methods: This study employed a retrospective design. Subjects were the head and neck cancer patients at a teaching medical center in central Taiwan who received “free flap reconstruction surgery”. A total of 60 patients were selected during November 2013 to April 2014 (30 of the subjects were treated inhalation anesthesia, and 30 subjects were treated intravenous anesthesia). The primary criterion for eliminating subjects was patients who had lung disease, uremia, ASA III, ASA IV, and age over 60 years old. The study variables are based on reviewing the medical records and anesthesia record sheets in order to obtain the basic patient information, diagnosis, treatments, operations, prognosis (pulmonary complications, infections, bleeding, and days in hospital), and anesthesia-related information (such as anesthesia methods, infusion volumes…etc). The analysis used the SPSS 18.0 statistical software package including Chi-square, independent t-test and others to conduct descriptive and inferential statistical analysis. Results: The results showed that there were no statistically significant differences between two anesthesia methods in patient’s characteristic of gender, ASA classifications, height, ages, weights and Body Mass Index (BMI); no significant differences in hypertension or diabetes (p> 0.05); no significant differences in treatments of electrotherapy or chemotherapy before surgery. However, there was a significantly associated between two anesthesia methods in postoperative pulmonary complications. Besides, the operation time, infusion volumes, and urine amounts were significantly differences (p< 0.05); but the losses of blood volume and central venous pressure showed no significant differences (p> 0.05). In addition, the durations of ventilator support and the days of stay in ICU between two different anesthesia methods were no noticeable differences (p>0.05), but the days stay in hospital has significant differences (p<0.05). Conclusions: The findings indicated that postoperative pulmonary complications are less likely to happen in free flap surgery patients who treated with total intravenous anesthesia. We also found that the amount of infusion volume for total intravenous anesthesia was significantly lower than the inhaled anesthesia. It is necessary to have professional anesthesia care for maintaining the fluid volumes to stabilize the patient’s hemodynamics in the time-consuming surgery. This study concluded that the total intravenous anesthesia method is the best valuable choice during free flap surgery.

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Dissertations / Theses on the topic 'Anesthesia complications'

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