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De Witte, Bavo. "Minimal chemical pollution, increased offshore wind farms and energy production sustainability." Open Access Government 41, no. 1 (January 22, 2024): 368–69. http://dx.doi.org/10.56367/oag-041-11178.
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Minimal chemical pollution, increased offshore wind farms and energy production sustainability Coordinator of the Anemoi project, Bavo De Witte (ILVO), discusses the path to minimal chemical pollution and increasing the sustainability of offshore wind energy. Offshore wind energy production is a relatively sustainable yet fast-growing industry, contributing to the UN development goals on green energy and climate actions. Europe’s total offshore wind power capacity as of September 2023 is 32 GW (1), only 20% of the European target to produce >150 GW by 2030. The vast increase in offshore energy production urged different European countries to monitor the potential effects of offshore wind farms (OWFs) on the marine ecosystem, including the impact of underwater noise, the introduction of novel habitats, and the exclusion of fisheries. However, the potential risk of chemical emissions by OWF structures remains largely unknown though estimated to be small.
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Maksimov, Vladimir I. "Old-Russian Stribog and his Ancient Greek Brother Astray." Russkaia Rech, no. 1 (February 2021): 57–63. http://dx.doi.org/10.31857/s013161170013904-3.
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The essay analyses the name of a pagan God of the Ancient Rus Stribog, who was mentioned in “The Russian Primary Chronicle” and “The Tale of the Igor’s Campaign” and its connection with the ancient Greek mythology. The article suggests that an old-Russian god Stribog is similar to the ancient Greek god Astray, the father of the famous gods of winds, Boreas — the god of cold northern wind, Zephyr — the god of warm western wind, Anemoi — the god of hot southern wind and Eurus — the god of unstable eastern or south-eastern wind, who are often associated with the winds they symbolize in Russian poetry. The similarity of Stribog and Astray lays not only in their origins, but in the common root str-. The article concludes that because god Astray is not only the farther of the gods of the winds, but also the father of Venus and other stars, it is arguable that Stribog is both the grandfather of the winds and the Slavic god of the night sky.
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Khanal, Babita, Sandip Pokhrel, Sandip Kumar Singh, Sunil Kumar Yadav, and Prakash Kafle. "Prevalence of Iron Deficiency Anemia among Under Five Years Children in a Tertiary Health Care Center of Nepal." Journal of College of Medical Sciences-Nepal 19, no. 3 (October 17, 2023): 288–93. http://dx.doi.org/10.3126/jcmsn.v19i3.55954.
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BackgroundGlobally 39.8% children under five years old are anemic, with prevalence of childhood anemia in Nepal reported to be 52.7% by 2016. The aim of this study is to analyze the prevalence of anemia among pediatric age group between 2 months to 60 months to provide some insight for prevention of anemia among children. MethodsThis is a prospective observational cross-sectional study conducted over the period of 15st March 2019 to 14th August 2019 at Nobel Medical College Teaching Hospital which included children presenting to pediatric department between ages 2 to 60 months. Children with known history of hemolytic disorders, malignancies and chronic diseases were excluded from the study. Hemoglobin level and Mean Corpuscular Volume (MCV) was obtained. Descriptive statistics such as mean, percentage and standard deviation were calculated. ResultsTotal 500 children selected randomly for the study, 234 (46.8%) children were non-anemic while mild anemia was seen in 86 (17.2%), moderate anemia in 155 (31.0%) and severe anemia in 25(5.0%) children. Mean hemoglobin was 10.2 gm/dl with standard deviation of 1.847. Among male 45.6% were anemic whereas 42.7%female were anemic. Children of age group 2 to 12 months had higher percentage of anemia with 76.2% being anemic. Among 266 anemic children 219 (82.3%) had MCV below the normal range. ConclusionOur study shows the higher prevalence of anemia in children between 2 to 60 months of age. Microcytic anemia was more common which represents higher prevalence of iron deficiency anemia among anemic children.
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SYED RAZI HAIDER ZAIDI, ALIYA MUZAFFER, SAIRA FAYYAZ, and AROOJ FATIMA NAQVI. "FEMALE LITERACY AND ANEMIA IN PREGNANCY: EXPLORING RELATIONSHIP." Pakistan Postgraduate Medical Journal 27, no. 3 (June 1, 2016): 72–74. http://dx.doi.org/10.51642/ppmj.v27i3.118.
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While anemia remains prevalent in all sexes yet pregnant females have higher prevalence which leads to complications and increases morbidity as well as mortality. The study aimed at exploring effect of female literacy in anemia in pregnancy so as to identify risk in illiterate women to enhance preventive strategies to high risk group as well as improving maternal education. Methodology: 60 anemic and 60 non anemic women from poor socioeconomic background were assessed for literacy. Results: Among the study participants mean age was 26 +/-1.7yrs in anemic and 32+/-3yrs in non-anemic. Mean income in study group was 12000rs +/-1000, in anemic women 42 had moderate anemia with mean Hb at 9.2g/dl +/- 0.6gg/dl while 18 had severe anemia with Hb at 6.1 g/dl +/-0.3g/dl, mean Hb in non-anemic women was 12.3g/dl +/-0.4gm/dl. In anemic group mean parity was at 3 while it was 2 in non anemic group. Out of 60 anemic women 14 were literate and 46 were not while among non anemic 33 were literate and 27 were not, p at 0.0004. Conclusion: Illiteracy is associated with anemia in pregnancy and require multi sectorial approach for educating and counseling females to reduces maternal and child morbidity and mortality.
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Singh, Rakesh Kumar, and Shraboni Patra. "Extent of Anaemia among Preschool Children in EAG States, India: A Challenge to Policy Makers." Anemia 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/868752.
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Background.India is the highest contributor to child anemia. About 89 million children in India are anemic. The study determines the factors that contributed to child anemia and examines the role of the existing programs in reducing the prevalence of child anemia particularly in the EAG states.Methods.The data from the latest round of the National Family Health Survey (NFHS-3) is used. Simple bivariate and multinomial logistics regression analyses are used.Results.About 70% children are anemic in all the EAG states. The prevalence of severe anemia is the highest (6.7%) in Rajasthan followed by Uttar Pradesh (3.6%) and Madhya Pradesh (3.4%). Children aged 12 to 17 months are significantly seven times (RR=7.99,P<0.001) more likely to be severely anemic compared to children of 36 to 59 months. Children of severely anemic mothers are also found to be more severely anemic (RR=15.97,P<0.001) than the children of not anemic mothers.Conclusions.The study reveals that the existing government program fails to control anemia among preschool children in the backward states of India. Therefore, there is an urgent need for monitoring of program in regular interval, particularly for EAG states to reduce the prevalence of anemia among preschool children.
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Mahjabeen, Nusrat, Shaikh Zinnat Ara Nasreen, and Safinaz Shahreen. "The Prevalence of Premature Rupture of Membranes (PROM) in Anemic and Non-anemic Pregnant Women at a Tertiary Level Hospital." European Journal of Medical and Health Sciences 3, no. 4 (July 6, 2021): 25–27. http://dx.doi.org/10.24018/ejmed.2021.3.4.934.
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The incidence of maternal and fetal morbidities and mortalities are very high in anemic patients. According to WHO anemia is the most common medical disease in pregnancy in south east Asian region. 18-20 pregnant women are anemic in developed countries as compared to the incidence is as high as 40% to 75% in south east Asian region. According to Center of Disease Control (CDC) anemia in pregnancy means hemoglobin is less than 11 g/dl (Hematocrit; {Hct} < 33%) in the first and third trimester and less than 10.5 g/dl (Hct < 32%) in the second trimester. According to World Health Organization (WHO), anemia in pregnancy is defined as Hb level is less than 11gm/dl. As physiological hemodilution occurs during pregnancy, pregnant women are at higher risk of anemia and more commonly iron deficiency anemia. The aim of the study is to compare the risk of PROM between anemic pregnant women and non-anemic pregnant women. It is a prospective observational study held in Z.H.Sikder women’s medical college & hospital from April,2020 to march,2021. 100 cases of anemic and 100 cases of non-anemic pregnant women were purposively taken as study population. The prevalence of PROM equaled to 64% in pregnant anemic group. In bivariable analysis, the risk factors of anemia such as, maternal working condition, socio economic status and maternal age were studied. The risk of PROM is higher in anemic pregnant women than in non-anemic pregnant women. Doctors and healthcare workers should be more careful to prevent and treat anemia in pregnancy to avoid the adverse outcomes.
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V., Sarala, and Ushadevi Gopalan. "A study on prevalence of anemia in pregnancy in South India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 1 (December 26, 2019): 34. http://dx.doi.org/10.18203/2320-1770.ijrcog20195617.
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Background: Anemia in pregnancy is a major health problem worldwide, especially in developing countries like India. Maternal and fetal outcomes are poor in pregnant patients with anemia. The most important cause of anemia is iron deficiency anemia which can be prevented by early oral iron supplementation.Methods: This cross-sectional study was conducted in the department of obstetrics and gynecology of our tertiary care teaching institution for a period of one year. 1290 pregnant women coming to the antenatal OPD were screened for anemia and 490 women. Patients who were not anemic were excluded. 800 patients were enrolled in the study. Each patient was interviewed using a structured interview schedule and the data obtained was analyzed.Results: The percentage of anemia in pregnant women was 62% in our study of which 40% were mildly anemic, 55% were moderately anemic and 5% were severely anemic. Maximum number of anemic women -mild, moderate and severe was seen in the age group 20-24 years. Mild and severe anemia was seen more in the secondary educated women. Maximum percentage of anemia was seen in the lower socio-economic status followed by middle and was lowest in the higher socio-economic status group. Prevalence of anemia was almost equal in primigravida and multigravidas (around 50%) but 80% of severely anemic patients were multigravida. Almost 68% took iron and folic acid tablets regularly.Conclusions: Treating anemia in pregnant women will go a long way in improving maternal and fetal outcome. Hence a future healthy younger generation can be produced. Iron tablets can be distributed at school to young girls to prevent anemia in future women.
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Witkos, Maciej, Michelle Uttaburanont, Myra Vicenio, Christopher Lang, and Rami Y. Haddad. "Effects of Anemia on the Rehabilitation Outcomes in Elderly Patients in the Post-Acute Care Setting." Blood 110, no. 11 (November 16, 2007): 5158. http://dx.doi.org/10.1182/blood.v110.11.5158.5158.
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Abstract Background - More than 3 million people in the United States over the age of 65 are anemic. The evidence indicates that older people with anemia suffer hospitalizations, physical decline and disability more than people without anemia. Additionally there are reports that anemia is an independent risk factor for this decline in physical performance in those over the age of 65. Objective - The goal of this study was to detail if anemia significantly affects patient’s rehabilitation outcomes by focusing on the ability to perform activities of daily living (ADL) as assessed by the physical therapist, the disposition upon discharge (meeting the therapy goals) and an analysis of length of stay (LOS) in relation to anemia. Methods - We conducted a chart review of 260 medical records of patients who underwent rehabilitation therapy at the North Chicago Veterans Affairs Medical Center, and detailed the progress of 69 of these patients who received ADL therapy. The study is ongoing with a projected chart review of 437 medical records, and with an estimated final sample size of 150. Univariate and multivariate analysis was conducted in relation to our outcome measures. Results - The anemic group had 43 patients and the non-anemic 26. Average values for anemic patients were: Hgb 11 Hct 32, MCV 88, MCH 29.2, RDW 15.6, Platelets 259, the non-anemic patients values were: Hgb 13.4, Hct 39, MCV 89, MCH 33.3, RDW 14.3, platelets 229. The patients with anemia had a median change in ADL scores of 9 versus non-anemic patients’ median change in scores of 12 (p=0.154). Length of stay was 51 days (median) for anemic patients and 36 days (median) for non-anemic patients (p=0.108) Of the non-anemic patients, 19 out of 26 (73%) met the goals of therapy and 21 out of 43 (49%) of the anemic patients met the goals of therapy (p=0.055). Surprisingly, only 3 out of the 43 (7%) anemic patients were treated for their anemia or had work up done to identify the cause of the anemia. The multivariate model for length of stay indicated that anemia was not significant (p=0.842), the morbidity of the patient was marginally not significant (p=0.089), however, the patients’ age was statistically significant at p=0.05. For the multivariate model of ADL improvement the results were: anemia p=0.186, sex p=0.298, Charlson index p=0.50. Conclusion - There is a definite lack in the identification and treatment of anemia in patients undergoing rehabilitation. Anemia exerts an influence on the course of patient therapy/recovery and should be addressed as an individual problem. Anemic patients undergoing rehabilitation are scoring lower, and are admitted longer to the hospital.
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Abdelaziz, Tarek A., Mohamed Almalky, Diana Hanna, and Eman Gamal Baz. "Prevalence of Helicobacter pylori Infection among Anemic School-Age Children in Egypt: A Cross-Sectional Population-Based Study." Journal of Child Science 11, no. 01 (January 2021): e317-e326. http://dx.doi.org/10.1055/s-0041-1740465.
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AbstractAnemia and Helicobacter pylori infection in school-age children are important public health problems. The association between H. pylori infection and the development of anemia, especially iron deficiency anemia, has been previously studied and until now it is still a matter of argument. This study aimed to determine the prevalence of anemia and H. pylori infection among school-age children and to find the association between H. pylori infection and anemia in school-age children. We conducted this population-based cross-sectional study in six Egyptian primary schools over a 12-month-period, including 1,200 students from all grades who fulfilled the inclusion criteria. The study participants were subjected to the following: medical history, clinical examination, and laboratory investigations included complete blood count and H. pylori antigen in stool, and according to the level of hemoglobin (Hb), we divided the students into two groups; the anemic group with Hb level <11.5 g/dL and nonanemic group with Hb level ≥11.5 g/dL, and the serum ferritin levels were measured only for the anemic group as the best indicator for iron status. The overall prevalence of H. pylori infection was 25%. The overall prevalence of anemia was 13.25%, of which hypochromic microcytic anemia represented 87.4% of the anemic group, and the mean ferritin level in the anemic group was 18.56 ± 9.96 ng/mL. The prevalence of anemia among H. pylori-infected patients (62.3%) was significantly (p < 0.001) higher than in noninfected children (37.7%). In the anemic group, the mean ferritin level in H. pylori-infected children was significantly lower than the mean level in the noninfected children (p <0.001). Furthermore, the anemic group had a significantly higher incidence of H. pylori infection and a lower age (p <0.001) in comparison with the nonanemic group. The dominant type of anemia in H. pylori-infected children was the microcytic hypochromic anemia, with a significantly higher incidence in comparison to other types of anemia (p <0.001). The findings of this study demonstrate a significant association between H. pylori infection and anemia in school-aged children, especially iron deficiency anemia, as the incidence of H. pylori infection was greater in anemic children than in non-anemic children.
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TASEER, IJAZ-UL-HAQUE, SOHAIL SAFDAR, AHSANULLAH MIRBAHAR, and ZARA AWAN. "ANEMIA IN PREGNANCY." Professional Medical Journal 18, no. 01 (March 10, 2011): 1–4. http://dx.doi.org/10.29309/tpmj/2011.18.01.1848.
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Objective: To see frequency of anemia and its related risk factors in pregnant women in an under developed area of Southern Punjab. Study design: Descriptive study. Setting: Ante natal outpatient clinic Tehsil Headquarter Hospital Kabirwala (Khanewal). Duration of the study: October2006 to March 2007. Sampling technique: Non-probability purposive. Methodology: Two hundred and fifty pregnant ladies attending ante natal outpatient clinic at Tehsil Headquarter Hospital Kabirwala (Khanewal) irrespective of reproductive age, socio economic, educational and residential status were included in this study. After taking consent a pre-designed proforma was filled in. Hemoglobin level was checked. Subjects were categorized according to the hemoglobin levels into mild (10.0-10.9 g /dl), moderate (8.0-9.9 g/dl) and severe (< 8.0 g/dl) anemia. Results: Two hundred and fifty pregnant women were studied. Mean age of the pregnant women was 28.28 ± 5.20 years. Out of these 250 pregnant women, 138 (55.2%) were anemic and out of these 83 (60.14 %) were moderately anemic while 55 (39.86 %) had mild anemia and none of these had sever anemia. Among participating pregnant women, 28 (11.2 %) were in 1st trimester, 85 (34 %) in 2nd trimester and 137 (54.8%) were in the 3rd trimester. Anemia was observed in 10 (35.71 %) women in first trimester, 35 (41.18%) in 2nd trimester and 93 (67.88 %) in 3rd trimester. One hundred and thirty two women were from rural background, out of these, 83 (62.88%) were anemic. Seventy were uneducated and out of these, 58 (82.88%) were anemic while 180 women were educated and of these 81 (45 %) were anemic. Ninety five (38 %) were having poor dietary habits and out of these, 78 (82.10 %) were anemic. One hundred eight pregnant ladies were not taking any iron supplement, out these 83 (76.85 %) were anemic while 142 (56.8 %) pregnant ladies were taking iron supplements, out of these 55 (38.73 %) were anemic. Twenty one pregnant women were with gravida more than 6 and out of these 19 (90.47 %) were anemic, of these 11 (57.89 %) had moderate anemia while 8 (42.10 %) were mildly anemic. Conclusions: The results of present study showed high frequency of anemia in the targeted population. Anemia was related with poor dietary habits especially poor iron intake. Anemia was more related with multi gravidity.
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Khoshdel, Z., and S. Tomas. "A Prospective Study on Impact of Anemia and Iron Supplementation in Pregnancy, Baptist Hospital, Bangalore, India." Pakistan Journal of Medical and Health Sciences 15, no. 5 (May 30, 2021): 1456–59. http://dx.doi.org/10.53350/pjmhs211551456.
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Aim: A prospective study on Impact of Anemia and Iron Supplementation in Pregnancy, Baptist Hospital, Bangalore, India Methodology: the prospective observational study was conducted for 6 months from September 2016_Febrry to 2017. All inpatients women who are pregnant and anemic. The patient data collection was used to collect all the details like inpatient number, age, sex, social history, history, laboratory data, diagnosis, therapeutic management. All inpatients diagnosed anemia in pregnancy and pregnant women without anemia. Fulfilling the inclusion criteria will be enrolled into the study and their prescriptions will be analyzed on daily basis. The prescription guidelines, Micromedex, interaction checker, drug interaction database, and Stockley's drug interaction book 8 edition. The drug interaction in prescription was collected and then compare with guidelines. When the analysis of prescription was completed then all data entered into the appropriate software and the results were gained. Results: The present study was focused to find out the presence of anemia in 110 pregnant women who were admitted to gynecology and OBG wards of BBH (Bangalore Baptist Hospital). Presence study showed that anemia was Confirmed in 50 patients. Of these 28(25.4%) of them diagnosed as mild anemic, 20 (18.1%) Of them with Moderate and 2(1.8%) of them as severe anemic patients. The result of this study showed that LBW is higher in anemic women 19(25%) compared to non-anemic 17(21%). Conclusion: The present study showed from a total of 110 patients were included in this study, anemia was confirmed in 50 patients. Of these 28(25.4%) of them diagnosed as mild anemic, 20(18.1%) Of them with Moderate and 2(1.8%) of them as severe anemic patients. More low-birth-weight (LBW) babies were born to anemic mothers. Anemia in pregnancy may be reduced by proper Iron and folic acid supplementation which can be improved through providing proper ANC services. Has also a recognizable association with fetal outcome. Keywords: Anemia, Iron, anemia, iron supplementation, pregnancy, low birth weight.
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A Ioannou, Ioannis, Richard Newton, Ben Clevenger, and David A H de Beer. "Prevalence of preoperative anemia in pediatric surgical patients and its impact on perioperative blood transfusion." Edorium Journal of Anesthesia 5, no. 2 (July 1, 2019): 1–9. http://dx.doi.org/10.5348/100019a05ii2019ra.
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Aim: To determine the prevalence of preoperative anemia in children presenting for surgery at our institution and to establish whether preoperative anemia increased the likelihood of perioperative transfusion. Methods: A retrospective review of all noncardiac surgical patients over a 2-week period. Data were collected for demographics, type of surgery, hemoglobin concentration within 28 days of surgery, severity of anemia and whether a blood transfusion was administered within 28 days of surgery. Results: 723 patients underwent non-cardiac surgery during the study period, of which 334 had a preoperative hemoglobin measurement, 116 of those were anemic. Blood transfusion was administered in 19.9% of all anemic patients, compared to 5.4% of non-anemic patients (odd ratio [OR] 4.383; 95% confidence interval [CI], 2.10–9.53; p less than 0.0001). In anemic children over six months of age, 75.3% were of moderate severity, 22.6% were mild, and 2.1% severe, with transfusion rates being similar 23.6, 15.1, and 33.0%, respectively. The prevalence of anemia increased with ASA severity with blood transfusion occurring more often in anemic than non-anemic patients in all ASA grades. Anemic patients who underwent intermediate or major procedures were significantly more likely to be transfused than their non-anemic counterparts, with no significant difference seen for minor procedures. Conclusion: Preoperative anemia is common in children presenting for surgery at our institution and in the majority of cases, this is of moderate severity. Preoperative anemia is associated with an increased likelihood of perioperative blood transfusion compared to patients with hemoglobin concentrations within the normal range.
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Tandoh, Marina Aferiba, Abigail Owusuaa Appiah, and Anthony Kwaku Edusei. "Prevalence of Anemia and Undernutrition of Adolescent Females in Selected Schools in Ghana." Journal of Nutrition and Metabolism 2021 (January 8, 2021): 1–5. http://dx.doi.org/10.1155/2021/6684839.
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Anemia among adolescent females is a major worldwide public health problem which should be given appropriate attention. Half of all anemic cases are caused by iron deficiency. In addition to anemia, poor nutrition is also a challenge in sub-Saharan Africa. This study determined the prevalence of anemia and undernutrition among adolescent females in school. A cross-sectional study was conducted among 151 adolescent females in four basic schools in the Ahafo region of Ghana. The hemoglobin level and anthropometry measures of participants were taken to determine their anemic and nutritional status. The prevalence of anemia among adolescent females in school was 50.3%. Out of the 151 participants, 6.6%, 19.9%, and 23.8% were severely anemic, moderately anemic, or mildly anemic, respectively. Only 2% of the participants were underweight, but the rate of stunting was 26.5%. The notable high prevalence of anemia that was found among adolescent females was correlated with other health and wellness concerns. Anemia and under nutrition negatively affect academic performance, productivity, and general wellbeing of adolescents; therefore, effective measures should be put in place to correct and eradicate these nutritional problems.
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Uba Nwose, Ezekiel. "Prevalence of Anemia and Risk of Adverse Bleeding Effect of Drugs: Implication for Therapy." Anemia 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/795439.
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This study aimed to evaluate the progress in reduction of prevalence of anemia in rural Australia. It also investigates the prevalence of hypoviscosity in anaemia with a view to determine the fraction of anaemic patients at risk of drug-inducible exacerbation of anemia. Archived clinical pathology data () for the period of 1999 to 2008 were utilized. The prevalence of anemia and hypoviscosity was evaluated by working out (i) the number that fell within anemia definition as a percentage of the population and (ii) the number that fell within hypoviscosity definition as a percentage of anemic patients. The prevalence in anemic diabetes and dyslipidaemia was further determined. There was progressive reduction in anemia from 6.1% to 3.2% over the ten years period. Prevalence of anemia is statistically significantly higher in males than in females (), but protein level is lower in anemic females than in anemic males (). The results further show that up to 75% of anemic patients may benefit from NSAID or salicylates. This paper highlights differences between genders. It suggests more concerted effort in men's health and speculates a new factor to investigate in women's health.
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Tandoh, Marina Aferiba, Abigail Owusuaa Appiah, and Anthony Kwaku Edusei. "Prevalence of Anemia and Undernutrition of Adolescent Females in Selected Schools in Ghana." Journal of Nutrition and Metabolism 2021 (January 8, 2021): 1–5. http://dx.doi.org/10.1155/2021/6684839.
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Anemia among adolescent females is a major worldwide public health problem which should be given appropriate attention. Half of all anemic cases are caused by iron deficiency. In addition to anemia, poor nutrition is also a challenge in sub-Saharan Africa. This study determined the prevalence of anemia and undernutrition among adolescent females in school. A cross-sectional study was conducted among 151 adolescent females in four basic schools in the Ahafo region of Ghana. The hemoglobin level and anthropometry measures of participants were taken to determine their anemic and nutritional status. The prevalence of anemia among adolescent females in school was 50.3%. Out of the 151 participants, 6.6%, 19.9%, and 23.8% were severely anemic, moderately anemic, or mildly anemic, respectively. Only 2% of the participants were underweight, but the rate of stunting was 26.5%. The notable high prevalence of anemia that was found among adolescent females was correlated with other health and wellness concerns. Anemia and under nutrition negatively affect academic performance, productivity, and general wellbeing of adolescents; therefore, effective measures should be put in place to correct and eradicate these nutritional problems.
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Liu, Z. G., Z. Y. Zhou, X. R. Wan, S. M. Zheng, and L. P. Yang. "Anemic pathogenesis of chicken infectious anemia." Pathophysiology 5 (June 1998): 155. http://dx.doi.org/10.1016/s0928-4680(98)80893-6.
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Hu, K., D. Shasha, P. Homel, and L. B. Harrison. "Prevalence, severity, and evolution of anemia in colorectal cancer patients receiving radiation therapy with/without chemotherapy: a retrospective analysis." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 13510. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.13510.
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13510 Background: Colorectal cancer (CRC) patients frequently present with anemia. Anemia may also develop or be exacerbated in CRC patients as a consequence of treatment with radiation therapy (RT) with or without (±) chemotherapy (CT). A better understanding of the relationship between anemia and RT ± CT is important as several studies have found that hemoglobin (Hb) levels are predictive of RT outcomes and that low Hb levels can diminish patient quality of life (QOL). However, the prevalence and evolution of anemia before and during RT ± CT are poorly characterized in CRC patients. Methods: Prospectively collected data from 81 CRC patients who received 10 weeks of curative-intent RT alone (26%) or in combination with CT (74%) were analyzed retrospectively to determine prevalence, severity, patterns and contributing factors of anemia. Results: Prior to RT ± CT, 38% of patients (n = 71, evaluable population) were anemic (defined as Hb ≤12 g/dL) and by the end of treatment, 61% were anemic (including 41% of patients not anemic and 93% anemic pre-treatment). A significant (P <.001) decrease in mean Hb for all patients was already apparent after <5 weeks RT ± CT, ie, from 12.6±2.0 g/dL to 11.5±1.8 g/dL, and the decrease in Hb remained consistent over time (see Table). The greatest Hb decrease was noted in patients not anemic pre-treatment, although not all became anemic. Multivariate analysis using logistic regression identified pre-treatment anemia (P = .0006) and age (P = .02) as the factors most strongly associated with intra-treatment anemia. Conclusions: Because anemia can adversely affect QOL and possibly also treatment outcomes in cancer patients, this condition needs to be addressed as part of the overall management of anemic colorectal cancer patients. [Table: see text] [Table: see text]
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Sinha, Kavita, Homnath Adhikari, Amrendra Kushwaha, and Goma Rimal. "Maternal and Perinatal Outcome in Anemic Pregnancies." Journal of Nepalgunj Medical College 18, no. 2 (August 9, 2021): 13–16. http://dx.doi.org/10.3126/jngmc.v18i2.38860.
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Introduction: Anemia in pregnancy is a public health problem of developing countries and has a significant impact on the health of mother and fetus. It is one of the leading cause responsible for maternal and perinatal morbidity and mortality. Aims: To find out the severity of anemia in pregnancy and its maternal and perinatal outcome. Methods: A prospective randomized case control study undertaken in the Department of Obstetrics and Gynecology, Nepalgunj Medical College, Kolhapur from September 2019 to August 2020. Total of 200 study subjects were enrolled, cases and control were 100 each, with cut off for anemia as 11gm/dl. Results: Out of 100 cases of anemia, 58 were mildly anemic (Hemoglobin: 10-10.9), 23 moderately (7-10) and 21 severely anemic (<7gm/dl). Anemic cases were found to have higher incidence of preterm birth (8%), postpartum hemorrhage (5%), and maternal morbidity (19%) than in non-anemic controls. Adverse fetal outcome in the form of preterm birth (8%), Intrauterine Growth Restriction (14%), Still birth (3%), Early neonatal death (4%), Low birth weight babies (22%), neonatal morbidity (17.5%) was more in anemic group than non-anemic controls. Conclusion: Anemia in pregnancy has adverse effects on the mother and fetus. It is important to diagnose and treat anemia in pregnancy to ensure optimal health of mother and newborn.
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Iwatsuki, Yoshiyuki, Koki Kitamura, and Ken-ichi Suzuki. "Shortened Lifespan of Red Blood Cells and the Effects of Erythropoietin in Rats with Nephrogenic Anemia." Blood 114, no. 22 (November 20, 2009): 1977. http://dx.doi.org/10.1182/blood.v114.22.1977.1977.
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Abstract Abstract 1977 Poster Board I-1000 Anemia is a common complication of chronic kidney disease (CKD), mainly due to the inability of the kidneys to secrete enough erythropoietin to adequately stimulate hematopoiesis. Further, given that the lifespan of red blood cells (RBCs) has been reported to be reduced in CKD patients, this reduction in RBC lifespan is believed to be a part of the etiology of renal anemia. In the present study, we focused on RBC survival and measured the lifespan of RBCs in rats with nephrogenic anemia. We also examined the effects of erythropoietin on RBC lifespan in this anemia model. Nephrogenic anemia was induced by oral administration of adenine (600 mg/kg/day for 10 days) to male Wistar rats. Progressive, serious anemia associated with increased levels of plasma creatinine was observed in the rats. On Day 40, the number of RBCs and hemoglobin (HGB) levels were lower in the adenine-treated rats than in normal, control rats (normal: 930×104/μL, anemic: 677×104/μL for RBC and normal: 17.2 g/dL, anemic: 13.4 g/dL for HGB). However, the number of reticulocytes did not change in the anemic rats (normal: 299×103/μL, anemic: 329×103/μL, P = 0.102). The percentage of annexin V-binding erythrocytes was increased in anemic rats (normal: 0.77%, anemic 1.76%) and inversely correlated with RBC count and HGB levels, suggesting that apoptosis of RBCs increased as anemia progressed. Taking these findings into account, we measured the lifespan of RBCs in rats with nephrogenic anemia. We transfused 5-chloromethylfluorescein diacetate (CMFDA)-labeled RBCs from normal donor rats into either normal or anemic recipients and determined the number of labeled RBCs present in the peripheral blood at various time points thereafter. The time course of the reduction in the percentage of labeled RBCs in peripheral blood revealed that the half-life (t1/2) of RBCs in anemic rats was shorter than in normal rats (normal: 22.5 d, anemic: 13.3 d). This reduction in RBC lifespan was also observed in a rat model of cisplatin-induced renal anemia. Injection of anemic rats with recombinant human erythropoietin (rhEPO) restored the number of RBCs and HGB concentration to normal levels. However, the t1/2of RBCs in these rats was not changed. The clearance of RBCs in anemic rats does not appear to be influenced by rhEPO injection. In conclusion, the survival of RBCs was reduced in rats with nephrogenic anemia, an observation consistent with the shortened survival time of RBCs in renal failure patients. This finding suggests that this model is suitable for investigating drugs which may be used in the treatment of renal anemia. Further, because EPO therapy did not affect the lifespan of RBCs, agents which improve the shortened RBC survival inherent in CKD patients may be useful in treating renal anemia. Disclosures: Iwatsuki: Astellas Pharma Inc.: Employment. Kitamura:Astellas Research Institute of America LLC: Employment. Suzuki:Astellas Pharma Inc.: Employment.
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Mary Sam, Sancy, and Padmaja Udaykumar. "DOES KNOWLEDGE AND INCREASED AWARENESS AMONG OUR FEMALE POSTGRADUATE MEDICAL STUDENTS CONTRIBUTE TO IMPROVE THEIR HEMOGLOBIN LEVELS?" Asian Journal of Pharmaceutical and Clinical Research 10, no. 10 (September 1, 2017): 347. http://dx.doi.org/10.22159/ajpcr.2017.v10i10.20264.
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Objective: Anemia is frequent among young women including medical students that remain unnoticed. This study was conducted to determine the prevalence of anemia in women postgraduate (PG) medics.Methods: Hemoglobin (Hb) level of the participants was estimated and correlated with history.Results: Eligible women PG medics (n=100) with a mean±standard deviation (SD) age of 25.92±1.5 years and body mass index (BMI) of 21.51±2.97 were enrolled. Of 44 anemic students, 32 had moderate anemia and 21 (47.73%) belonged to the 3rd year postgraduation. Only 16 students were underweight, eight in anemic and non-anemic group each. None had any history of occult bleeding. Twenty-four (24.0%) students had taken anti-helminthic treatment within 6 months before enrollment. Mean Hb levels were 11.54±1.21 g/dL. There was a statistically significant difference (p<0.05) between mean Hb level of the anemic students (Hb - 10.35 g/dL) and the non-anemic individuals (Hb 12.49 g/dL). There was no statistical significant difference (p>0.05) in the occurrence of anemia among vegetarians (mean±SD Hb 11.21±1.11 g/dL) and non-vegetarians (mean±SD Hb 11.61±1.23 g/dL). There was no statistical significance (p>0.05) in Hb level/anemia and BMI, dietary habits, duration, and heavy flow during menstruation between non-anemic and anemic students.Conclusion: Anemia is still a concern in young women, and PG medical students are no exempt. Although none had severe form, anemia of moderate severity is prevalent among our PG students. Dietary habits did not influence or contribute to the maintenance of adequate Hb levels. Knowledge increased awareness and being self-sufficient did not contribute to maintain adequate Hb level.
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Al-hajjiah, Nasma N., and Mohammed A Almkhadree. "THE EFFECT OF MATERNAL ANEMIA ON THE ANTHROPOMETRIC MEASUREMENTS IN FULLTERM NEONATES." Asian Journal of Pharmaceutical and Clinical Research 11, no. 4 (April 1, 2018): 422. http://dx.doi.org/10.22159/ajpcr.2018.v11i4.25579.
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Objective: The current study was performed to understand the effect of maternal anemia and its severity on anthropometric measurement of full-term neonates.Methods: In this study, 254 pregnant women were involved in this study. The women with anemia were classified depending on the hemoglobin concentration into three groups of mild (10.9–9.0 g/dl), moderate (8.9–7.0 g/dl), and severe anemia (˂7.0 g/dl). The anthropometric measurements of the newborns were measured including birth weight, length, and head and chest circumference. Mothers with chronic diseases, preterm neonates, postdate neonates, neonates with congenital anomalies, or critical illnesses had been excluded from the study.Results: A total of 147 (58%) mothers had normal hemoglobin levels, and 107 (42%) mothers were anemic. The newborns were 123 males and 131 females. From the anemic mothers, 59 (55%) neonates had low weight, and 48 (45%) neonates had normal weight. In mothers with mild anemia (n=83), 40 (48%) neonates had low weight. In mothers with moderate anemia (n=21), 16 (76%) neonates had low weight. In mothers with severe anemia (n=3), all of their neonates had low weight. The current study revealed a statistically significant difference (p=0.002) in the anthropometric measurement of the full-term neonates between anemic and non-anemic mothers. There was also a statistically significant difference (p=0.001) in the anthropometric measurement of the full-termed neonates between severely and mildly anemic mothers.Conclusion: The current study shows that maternal anemia affects the anthropometric measurements of newly delivered full-term neonates. Neonates born to anemic mothers had low birth weight and shorter length than those in neonates who were born to non-anemic mothers.
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Rugea Mahmud Mahmmed. "Effect Of Maternal Iron Deficiency Anemia On The Baby Anthropometric Measurements And Hematological Indices." Scientific Journal of University of Benghazi 33, no. 2 (December 31, 2020): 6. http://dx.doi.org/10.37376/sjuob.v33i2.252.
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Anemia is one of the most prevalent nutritional deficiency problems afflicting pregnant women. Objective: - to evaluate the impact of maternal anemia on the baby anthropometric measurements (B. weight, length, head circumference) & biochemicals (HB, S. iron, S. ferritin). Prospective cross-sectional hospital based study was conducted on 200 Pregnant women attending labor room at AL-Jamhoria hospital from 1st April to end of May 2012, aged between 18-42years old, who delivered vaginally. Maternal venous blood was extracted few hours before delivery for (Hb, S. iron, S. ferritin) and umbilical cord blood immediately after delivery for baby (Hb, s. ferritin, s. iron) and babies' anthropometric measurements (B. weight, Length, Head circumference) were taken. 85(42.5%) of total 200 pregnant women were anemic where (27%, 15.5%, 0%) with mild, moderate and severe anemia respectively, with hemoglobin levels (10- 10.9 g/dL, 7- 9.9 g/dL, ≤ 7 g/dL) respectively. 177 (88.5%) of them received iron supplement where (54%, 21.5%, 13%) among control, mild anemia & moderate anemic groups respectively, the mean maternal hemoglobin for control, mild anemic & moderate anemic groups were (12.15±0.82, 10.45±0.30, 8.97±0.74) respectively. The mean maternal iron level for control, mild anemic & moderate anemic groups were (86.35±38, 74.77±2.77, 59.38±35.6) respectively, the mean babies iron levels were (41.2± 1.38, 39.3± 1.38, 37.4± 1.34) for control, mild anemic & moderate anemic groups respectively. The mean maternal ferritin level for control, mild anemic, moderate anemic groups were (40.65±1.88, 24.03±39.52, 13.79±13.37) respectively with mean babies ferritin level for control, mild anemic & moderate anemic groups were (260± 2.63, 321± 2.79, 195± 1.91) respectively. The Anemia is highly prevalent among pregnant women in our country and reaches 42.5% & have impact on the baby growth & hematological indices.
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Danaah Malick, Martin Mumuni, Aloysius Maalekuu, and Odalys Hernandez Rivera. "Prevalence and Factors Associated with Anemia in Pregnancy among Women Receiving Antenatal Care at the West Gonja District Hospital of Northern Ghana." International Journal of Innovative Research in Medical Science 5, no. 08 (August 1, 2020): 271–83. http://dx.doi.org/10.23958/ijirms/vol05-i08/915.
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Background: Anemia in pregnancy is a major public health problem especially in Low and Middle-income countries (LMIC) including Ghana and is defined by the World Health Organization (WHO) as being present when the hemoglobin concentration in the peripheral blood is 11g/dl or less. In most African countries anemia in pregnancy occurs if the hemoglobin concentration falls below 10g/dl. Pregnant women are at a higher risk of developing anemia due to several factors such as hemodilution, nutritional factors, multiple gestation, socio-economic status and malaria infestation. Anemia in pregnancy is an important cause of maternal mortality and affects half of pregnant women worldwide; with 56% of West African pregnant women being anemic. The objective of this study is to assess the prevalence and identify the risk factors associated with anemia among pregnant women receiving antenatal care at the West Gonja Hospital(WGH) Methods: A cross-sectional was conducted with 136 pregnant women receiving antenatal care at the WGH between January 2017 to February 2018. Random sampling was used to select participants and data was collected using a structured questionnaire. Data was analyzed using the SPSS Version 24.0. Results: A total 71(52.2%) of the study population were anemic, while 65 (47.8%) were not anemic. 20(74.1%) of the 27 pregnant housewives were anemic, while 11(64.7%) of the pregnant farmers were anemic. 27 (96.4%) of the 28 pregnant women who took their iron/folate supplement only some few days were anemic. 12 (100%) of the 12 participants who took their iron/folate supplement a few times a week were anemic. 4 (80%) of the 5 participants who never took their iron/folate supplement were anemic. 21 (70%) of those who did not sleep under ITN were anemic. 33 (84.6%) of the 39 patients who were diagnosed with malaria were also anemic. 28 (87.5%) of the 32 participants who took only 2 meals a day were anemic. 27 (79.4%) of the 34 patients who took liver, beef, chicken and fish only twice weekly were anemic. 15 (88.2%) of the 17 patients who drank tea some days in a week were anemic. Conclusion: Although most of the pregnant women were adequately educated on the most relevant aspects of anemia in pregnancy, more than half of them were still anemic. Anemia was more prevalent among pregnant uneducated housewives with poor nutritional habits. All the pregnant sickle cell disease patients as well as those diagnosed with malaria were also anemic.
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Malick, Martin. "Prevalence and factors associated with anemia in pregnancy among women receiving antenatal care at the West Gonja District Hospital of Northern Ghana." Obstetrics Gynecology and Reproductive Sciences 4, no. 3 (December 14, 2020): 01–12. http://dx.doi.org/10.31579/2578-8965/042.
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Background: Anemia in pregnancy is a major public health problem especially in Low and Middle-income countries (LMIC) including Ghana and is defined by the World Health Organization (WHO) as being present when the hemoglobin concentration in the peripheral blood is 11g/dl or less. In most African countries anemia in pregnancy occurs if the hemoglobin concentration falls below 10g/dl. Pregnant women are at a higher risk of developing anemia due to several factors such as hemodilution, nutritional factors, multiple gestation, socio-economic status and malaria infestation. Anemia in pregnancy is an important cause of maternal mortality and affects half of pregnant women worldwide; with 56% of West African pregnant women being anemic. The objective of this study is to assess the prevalence and identify the risk factors associated with anemia among pregnant women receiving antenatal care at the West Gonja Hospital (WGH) Methods: A cross-sectional was conducted with 136 pregnant women receiving antenatal care at the WGH between January 2017 to February 2018. Random sampling was used to select participants and data was collected using a structured questionnaire. Data was analyzed using the SPSS Version 24.0. Results: A total 71(52.2%) of the study population were anemic, while 65 (47.8%) were not anemic. 20(74.1%) of the 27 pregnant housewives were anemic, while 11(64.7%) of the pregnant farmers were anemic. 27 (96.4%) of the 28 pregnant women who took their iron/folate supplement only some few days were anemic. 12 (100%) of the 12 participants who took their iron/folate supplement a few times a week were anemic. 4 (80%) of the 5 participants who never took their iron/folate supplement were anemic. 21 (70%) of those who did not sleep under ITN were anemic. 33 (84.6%) of the 39 patients who were diagnosed with malaria were also anemic. 28 (87.5%) of the 32 participants who took only 2 meals a day were anemic. 27 (79.4%) of the 34 patients who took liver, beef, chicken and fish only twice weekly were anemic. 15 (88.2%) of the 17 patients who drank tea some days in a week were anemic. Conclusion: Although most of the pregnant women were adequately educated on the most relevant aspects of anemia in pregnancy, more than half of them were still anemic. Anemia was more prevalent among pregnant uneducated housewives with poor nutritional habits. All the pregnant sickle cell disease patients as well as those diagnosed with malaria were also anemic.
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Kaul, Indu, Isha Sunil, and Aakriti Gupta. "Maternal haemoglobin and perinatal outcome in a tertiary care hospital in Jammu city, India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 11 (October 28, 2017): 5060. http://dx.doi.org/10.18203/2320-1770.ijrcog20175026.
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Background: Maternal anemia is a common problem worldwide. The objective of this study was to assess the prevalence of anemia in women attending a tertiary care centre in their third trimester of pregnancy and to study the relation of maternal hemoglobin with perinatal outcome.Methods: This study was conducted in the Department of Obstetrics and Gynecology, SMGS Hospital, Jammu for a period of one year from Nov. 2015 to Oct. 2016. A total of 767 women in their third trimester (>28 weeks) were enrolled and were followed till delivery. Their hemoglobin levels were noted and its association with adverse maternal and fetal outcomes was studied.Results: It was seen that out of 767 patients, 193 (25.16%) were non-anemic and 574 (74.83%) were anemic out of which 343 (44.71%) were mildly anemic, 160 (20.86%) had moderate anemia and 70 (9.12%) had severe anemia. There was increased incidence of preterm delivery, PPH, preeclampsia, eclampsia, CCF, mortality & blood transfusions in the anemic group as compared to the non-anemic group. Among the adverse fetal outcomes, there was increased incidence of intrauterine deaths, intrauterine growth restriction, NICU admissions, meconium stained liquor, low birth weight babies and APGAR scores <7/10 among the anemic group as compared to the non-anemic group.Conclusions: Maternal anemia is a significant risk factor for adverse maternal and perinatal outcome and its prevalence continues to be high especially in developing countries like India. So, correction of maternal anemia still remains one of the most important step towards better obstetrical care.
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Mangla, Divya, Sheetal Gole, Nikhil Bansal, Sushma Yadav, Ravinder Kharolia, and Abhishek Singh. "Risk factors of severe anemia among the pregnant women from an underprivileged rural area of northern India: a multivariate analysis." International Journal Of Community Medicine And Public Health 9, no. 10 (September 28, 2022): 3824. http://dx.doi.org/10.18203/2394-6040.ijcmph20222578.
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Background: India serves as a home to 45.7% of anemic pregnant women (aged 15-49) with anemia of any grade during the course of their pregnancy. This study aims to estimate the prevalence of anemia and associated risk factors of severe anemia among pregnant women.Methods: Eligible antenatal women irrespective of period of gestation were screened for presence of anemia with help of hemoglobin (Hb) value at the time of admission. Typing of anemia was done. Detailed history was followed by physical examination. Univariate and multivariate analysis was done to study the risk factors of severe anemia among the study subjects.Results: Of total, 22.1% women were found to be severely anemic. Severely anemic women having residence in a rural area without road had odds more than twice (AOR=2.14) compared to severely anemic women having residence in a rural area connected with road (p=0.018). Similarly, severely anemic women aged <25 years (AOR=2.70), Illiterate (AOR=3.12), marriage age <18 years (AOR=2.33), having age at 1st pregnancy as <19 years (AOR=1.93), undergone ≤3 ANC visits (AOR=3.95). Anemic women with gravida score ≥4 had more than 4 times risk (AOR=4.15).Conclusions: The significant risk factors of severe anemia among pregnant women as observed in this study were having residence in a rural area without road, age <25 years, illiteracy of mother, marriage age (<18 years in completed years), age at 1st pregnancy as <19 years, ≤3 ANC visits, gravidity ≥4 and non-sanitary type toilet facility at home.
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Ningsih, Oliva Suyen, Eugenius Rada Masri, Claudia Fariday Dewi, Mariana Nona Rafael, Bernadeta Dudet, Eduardus Jarut, Antonia Mareti Mbulu, et al. "SCREENING DAN PENDIDIKAN KESEHATAN PENCEGAHAN ANEMIA PADA REMAJA PUTRI." JMM (Jurnal Masyarakat Mandiri) 7, no. 1 (February 1, 2023): 317. http://dx.doi.org/10.31764/jmm.v7i1.12073.
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Abstrak: Perubahan fisik dan fisiologi pada remaja membuat remaja rentan mengalami Anemia. Anemia pada remaja berdampak negatif pada perkembangan kognitif, fisik dan emosional. Kegiatan ini bertujuan mengidentifikasi remaja dengan Anemia dan melakukan pendidikan kesehatan tentang Anemia. Kegiatan ini dilakukan pada Sekolah Menengah Atas yaitu di SMK Bintang Timur dan Sekolah Menengah Pertama yaitu SMPN 1 Wae Ri’i dan SMPN 3 Langke Rembong berjumlah 95 siswa pada November 2022. Metode kegiatan mencakup screening Anemia dan penyuluhan kesehatan. Hasil yang dicapai melalui screening beberapa remaja mengalami Anemia berdasarkan pemeriksaan fisik yaitu konjungtiva anemik sebanyak 3 remaja (3,2%), wajah pucat sebanyak 5 remaja (5.3%), bibir, kulit, kuku dan telapak tangan pucat sebanyak 2 remaja (2.1%). Berdasarkan screening tanda dan gejala Anemia beberapa remaja mengalami letih, lesu dan lelah (28.4%), sakit kepala, pusing serta mata berkunang-kunang (32.6%), mengantuk, cepat lelah dan sulit konsentrasi (28.4%). Hasil evaluasi dengan metode post-test menunjukkan bahwa pengetahuan remaja mengenai Anemia telah meningkat sebanyak 85%.Abstract: Physical and physiological changes in adolescents make adolescents susceptible to anemia. Anemia in adolescents has a negative impact on cognitive, physical and emotional development. This activity aims to identify adolescents with anemia and conduct health education about anemia. This activity was carried out at senior high schools, namely at Bintang Timur Vocational School and junior high schools, namely SMPN 1 Wae Ri'i and SMPN 3 Langke Rembong with a total of 95 students in November 2022. Activity methods include anemia screening and health education. The results achieved through screening several adolescents experiencing Anemia based on physical examination, namely anemic conjunctiva in 3 adolescents (3.2%), pale faces in 5 adolescents (5.3%), pale lips, skin, nails and palms in 2 adolescents (2.1%). Based on screening for signs and symptoms of anemia, some adolescents experienced fatigue, lethargy and fatigue (28.4%), headaches, dizziness and dizzy eyes (32.6%), drowsiness, fatigue and difficulty concentrating (28.4%). The results of the evaluation using the post-test method showed that adolescents' knowledge about anemia had increased by 85%.
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Ashwini Aithal, P., A. Binti Amber, C. Wen Hao, H. Elang Gopalan, S. Krishnappan, V. Upeka Goonesinghe, and N. Kumar. "Incidence and factors associated with anemia among the geriatric population at a tertiary care hospital in southern India." Rwanda Medical Journal 80, no. 1 (March 31, 2023): 29–34. http://dx.doi.org/10.4314/rmj.v80i1.4.
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INTRODUCTION: Anaemia in geriatric populations poses challenges to healthcare systems worldwide. Hence, this study was done to investigate the incidence of anemia among the geriatric population of South India. METHODS: Retrospective, cross-sectional study with 144 patients aged 65 years and above. Socio-demographic data and laboratory findings were recorded in a validated proforma format. Data were analyzed using SPSS.RESULTS: 36.1% of the study population was anemic, and 63.9% were non-anemic. The prevalence of anemia was higher among females (36.36%) than males (35.82%). The prevalence of anemia was significantly correlated with advanced age (r=0.21; p < 0.05) and female sex (r=0.25; p < 0.05). Thirty-six patients were mild anemic (69%), 13 had moderate (25%), and 3 (6%) had severe anemia. Nutritional anemia was most common (80%), followed by hemorrhagic anemia (18%) and hemolytic anemia (2%). Among the 52 patients who were anemic, the most common comorbidities associated were Type 2 diabetes mellitus (69.2%) and hypertension (53.8%). Liver diseases were present in 5 cases (9.62%), renal insufficiency in 14 cases (26.9%), hypercholesterolemia in 5 cases (9.62%), and 6 cases (11.5%) were associated with other diseases. All the patients were managed conservatively with treatment, and anemia improved in 36.5% of cases.CONCLUSION: Anaemia was frequently diagnosed in the studied geriatric population. Nutritional deficiencies were the most common cause, followed by hemorrhagic and hemolytic anemia. The impact of anemia on quality of life, recovery from illness, and functional abilities must be further investigated in future geriatric studies.
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MATUR, ERDAL, ELIF ERGUL EKIZ, MERT EREK, EZGI ERGEN, SUAT HAYRI KÜÇÜK, SONGÜL ERHAN, and MUKADDES ÖZCAN. "Relationship between anemia, iron deficiency, and platelet production in dogs." Medycyna Weterynaryjna 75, no. 02 (2019): 6233–2019. http://dx.doi.org/10.21521/mw.6233.
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Platelet production increases in anemic people. In particular, iron deficiency causes reactive thrombocytosis in such patients. Although anemia and iron deficiency are frequently seen in dogs, there are no published studies on this subject. The aim of the present study was to investigate the relationship between anemia, iron deficiency, and platelet production in dogs. A total of 81 dogs brought to the university animal hospital with signs of anemia were used. Haemogram parameters, serum iron (Fe), erythropoietin (EPO), and thrombopoietin (TPO) levels, as well as total iron binding capacity (TIBC), were measured. Transferrin saturation (TSAT) ratios were calculated. The animals were categorized as anemic or non-anemic, mildly anemic or moderately/ severely anemic, and having iron deficiency or no iron deficiency according to haemogram parameters and the serum Fe level. A high platelet number was observed in dogs with mild anemia. Dogs with mild anemia also had higher serum EPO levels than dogs with moderate/severe anemia (P = 0.047). Iron deficiency was detected in 31 dogs. The platelet number was higher in dogs with iron deficiency (P = 0.004). It was also observed that dogs with iron deficiency had higher serum EPO levels (P = 0.027) and lower TPO levels (P = 0.025) than dogs without iron deficiency. In conclusion, it can be said that mild anemia and iron deficiency cause thrombocytosis in dogs. The increased serum EPO levels, both in dogs with mild anemia and those with iron deficiency, suggest that the increase in platelet production is due to EPO. Nevertheless, there is a need for further research to fully understand the underlying mechanism.
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von Drygalski, Annette, and Julie Biller. "Anemia in Cystic Fibrosis (CF): Prevalence, Mechanisms and Correlation with Pulmonary Function." Blood 108, no. 11 (November 16, 2006): 1286. http://dx.doi.org/10.1182/blood.v108.11.1286.1286.
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Abstract CF is a chronic disease associated with inflammation and an unknown prevalence of anemia. In other settings anemia is associated with increased morbidity and mortality, and recognition and correction of anemia in CF patients might lead to better outcomes. We hypothesized that chronic inflammation (ACI), iron deficiency (IDA) and malabsorption may be important mechanisms contributing to the anemia in CF patients. METHODS: Clinical charts and portCF.org visit logs of 218 patients of all ages (1 m to 61 yrs) with CF were reviewed for as many years as charts permitted (range 1–7 yrs). The following data were extracted: CBC, iron studies, pulmonary function tests (PFTs), vitamins A, D, and E levels, creatinine, pertinent medical history, and current medications. Anemia was defined by age- and gender-specific WHO criteria. Patients were considered anemic if low Hb was present on two separate occasions at least two months apart, or average annual Hb met WHO criteria. PFTs in 176 patients (all >6 yrs) included forced expiratory volume (FEV1) and forced vital capacity (FVC) as percent predicted of normal and were considered a reflection of patient performance. The most representative annual PFT from at least 4 annual tests was chosen for analysis since acute infection adversely influences daily performance. Semiannual vitamin levels of 47 adults were correlated with corresponding Hb values. RESULTS: 61 of 218 patients, ages 1 m to 61 yrs, were anemic (prevalence 28%). The percent of anemia in different age groups varied. Children <11yrs had a prevalence of anemia of 18.5% while adolescents had a prevalence of only 4%. Of 111 adults >18 yrs, 48 were anemic (43%) with a progressive age-related increase in the prevalence of anemia reaching 58% in patients >40 yrs. Complete iron studies were available in 16/48 patients. 7 were identified as IDA, 4 as ACI, and 3 as combined; 2 others had renal failure. In 32 patients, iron studies were incomplete, but renal failure, hemoptysis, hematochezia and solid organ transplants were contributing factors in half. PFTs obtained in 176 patients >7 yrs were compared in anemic and non-anemic patients. Mean FEV1 and FVC at all ages were statistically significantly poorer in the anemic patients (p <0.005). There was no correlation between vitamin levels and Hb. Complete iron studies were also available in 9 non-anemic patients with impaired lung function. 8/9 patients had ferritins <35 ng/ml. Transferrin saturation was <18% in 7 and 21% and 23% in the remaining 2, suggesting relative iron deficiency. CONCLUSIONS: The prevalence of anemia in CF patients is high and increases with age. In patients for whom iron studies were available, IDA was the prominent underlying mechanism, followed by ACI or a combination of both. There was no correlation between fat soluble vitamin levels and Hb, indicating malabsorption is not a major contributor to the anemia. There was a strikingly significant association between anemia and poor pulmonary function in all age groups. In addition, a group of non-anemic patients with poor lung function had relative iron deficiency. Our results indicate that iron deficiency in anemic CF patients, as well as relative iron deficiency in non-anemic CF patients might be underrecognized and undertreated. Since anemia is associated with poor pulmonary function, correction of anemia should be attempted. Identification of relative iron-deficient states in non- or borderline anemic CF patients with poor lung function could be important since iron supplementation might allow Hb levels to increase as an appropriate response to hypoxia.
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Quaderi, Humaira Rafiqa, Md Mahbubul Hoque, Nawshad Uddin Ahmed, Dilruba Begum, and Bithi Debnath. "Prevalence of Anemia in Children Aged Six Months to Thirty Six Months - A Hospital Based Study." Bangladesh Journal of Child Health 40, no. 2 (February 13, 2017): 98–102. http://dx.doi.org/10.3329/bjch.v40i2.31565.
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Background: Anemia is a common problem in childhood, especially children aged 6months to 24 months old. In Bangladesh overall, 68 % of children aged 6-59 months are anemic. Anemia impairs normal development, decreases physical exercise tolerance & intellectual performance in children which may lead to a slowdown of growth in children. It constitutes a major public health problem in young children in the developing world with wide social & economic implications.Objective: To see the prevalence of anemia among hospitalized children aged 6 months to 36 months.Methodology: Children 6 months 36 months aged who were admitted in Dhaka Shishu (Children) hospital due to some acute illness, were enrolled from 1st June, 2010 to 30th August, 2010. Children were classified as anemic when Hb level was <11gm/dl. On the values of MCV and morphology of RBC anemic babies were further classified as microcytic anemia, normocytic anaemia and macrocytic anaemia. Again in children with microcytic hypochromic RBC, serum ferritin, Hb electrophoresis, stool R/E and c-reactive protein were done to find out the cause.Results: Among 331 admitted children, 201(61%) children had anemia (Hb <11gm/ dl), Male was 123(61.2%) and female was 78(38.8%). Mean hemoglobin concentration was 9.2±1.2 gm/dl. Mild, moderate, severe anemia were19%, 39.3% and 2.4% respectively. The most affected age group was 6-23 months(76%). Microcytic anemia, macrocytic anemia, and normocytic anemia were present in 101(50.2%), 10(5%) and 90(44.8%) cases respectively. Among the microcytic hypochromic anemia, IDA was found in 60(59.4%), which was 29.85% among total anemic children.Conclusion: A large proportion of hospitalized children under 3 years were found anemic. Raising awareness of the problem and providing health care education in this group will be the key strategies to prevent and control this huge public health problem in Bangladesh.Bangladesh J Child Health 2016; VOL 40 (2) :98-102
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Reddy A., Bhaskar, V. Sharath Chandra, and Zion Eluzai. "Prevalence and types of anemia among children at a tertiary care hospital." International Journal of Contemporary Pediatrics 5, no. 4 (June 22, 2018): 1431. http://dx.doi.org/10.18203/2349-3291.ijcp20182541.
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Background: The anemic children tend to have average or below average academic performance due to effect of anemia on cognitive and behavioral aspect of the child. The objective of the study is to study prevalence and types of anemia among children at a tertiary care hospital.Methods: A total of 6000 patients attended the outpatient department of the SVS hospital, Mahabubnagar during the study period. Out of them 1237 patients were pediatric patients who attended the pediatric outpatient department. Among these 1237 children, 823 children were found anemic. Among these 823 anemic children, 100 were randomly included in the present study for further investigations. Thus, final sample size of the present study was randomly selected 100 anemic children.Results: The incidence of anemia was found to be very high i.e. 66.5%. It was found that the prevalence of anemia was 60.9% among females compared to only 39.1% among male children. The prevalence of anemia was significantly higher in females compared to males. In both males and females, the iron deficiency anemia was the most common type of anemia found in the present study. Maximum prevalence of iron deficiency anemia was seen in 1-5 years of age in females. Maximum prevalence of iron deficiency anemia was seen in 1-5 years of age in males. The most common grade of anemia was moderate grade followed by mild.Conclusions: Iron deficiency anemia is more prevalent in female children. In males also, it is not found to be very low. Its prevalence in males is also noticeable.
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Perveen, Ayesa, Fatema Ashraf, Rooh E. Zakaria, Rabeya Khanam, AKM Zahirul Haq, and Hasina Begum. "Effect of Anemia on Pregnancy Outcome in Labour Ward: Study in a Tertiary Level Public Hospital." Journal of Shaheed Suhrawardy Medical College 11, no. 2 (September 20, 2020): 155–60. http://dx.doi.org/10.3329/jssmc.v11i2.49301.
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Objectives: To determine the pregnancy outcome among anemic women admitted in labour ward of a tertiary level hospital.
Methodology: This is a descriptive type of cross-sectional study. All women who were admitted at labour room for delivery with anemia and gestational age more than 28 weeks were included with purposive sampling under the GU-3 of Shaheed Suhrawardy Medical College & Hospital. Respondents were recruited on the basis of clinical findings correlating with lab investigation. Blood samples were collected during the time of admission and hemoglobin (Hb) level were tested by automated machine in the laboratory of ShSMCH. Outcome of pregnancy was observed against the anemic state defined by Hb% done in laboratory. The mother who delivered, intra-partum & post-partum observation up to 7 days were made for pregnancy outcome.Results: This study conducted in a tertiary level public hospital, included 100 pregnant anemic mothers admitted at labor ward. Prevalence of anemia was 30.12% among the pregnant women at delivery. It revealed that women went into labor having mild anemia in 77% and moderate anemia in 23% cases. Importantly it was observed that moderate anemia was found more in younger age group. Additionally, it was also more pronounced (>50%) among the illiterate and primary education group. There was significant inverse relationship between educational status (p =.003) and anemia. Regarding family history, about two thirds anemic mother came from nuclear family and they also lives with small members. Most of the multigravida women presented with moderate anemia. Among the moderately anemic mothers’ interval of pregnancy were less than two years. It has been observed that 60.9% moderate anemic mother was not on regular antenatal checkup and total 11% respondents had no antenatal checkup. Regarding maternal outcome preterm labour (PTL), premature rupture of membrane (PROM), wound infection were more among moderately anemic group. There was significant relationship between degree of anemia with birth weight (p=.014). Adverse fetal outcome like prematurity, NICU admission, IUD were found more among moderately anemic mothers.
J Shaheed Suhrawardy Med Coll, December 2019, Vol.11(2); 155-160
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Kim, Eun Young, and Youn-Jung Son. "Association between Anemia and Cognitive Impairment among Elderly Patients with Heart Failure." International Journal of Environmental Research and Public Health 16, no. 16 (August 15, 2019): 2933. http://dx.doi.org/10.3390/ijerph16162933.
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Cognitive impairment is more prevalent in heart failure (HF) patients. Anemia can influence cognitive ability and is likely more prevalent in elderly patients with HF. However, there are limited data on the association of anemia with cognitive impairment in elderly HF patients. This study aimed to identify the association between anemia and cognitive impairment in elderly HF patients. This secondary data analysis included 181 patients aged 60 years or older with HF. Patients were categorized into an anemic or non-anemic group based on World Health Organization (WHO) criteria. We assessed the cognitive function using the Modified Mini-Mental State (3MS) at the time of enrollment. The prevalence of anemia and cognitive impairment in older patients with HF was the same at 35.4%. The main finding of the multiple logistic regression indicated that compared to a non-anemic status, anemia increased the risk of cognitive impairment (odds ratio (OR) = 4.268, 95% confidence interval (CI) = 1.898–9.593, p < 0.001). Healthcare providers should recognize the value of the significance of early assessment of anemic status and cognitive function following HF. A prospective cohort study should identify the pathway of the association between anemia and incidence of cognitive impairment.
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Kidwai, Mohammad Moaaz, V. R. Anand, and Deepika Gulathi. "Effect of maternal hemoglobin and iron status on fetal hemoglobin, iron status, growth and maturity." International Journal of Contemporary Pediatrics 9, no. 1 (December 24, 2021): 62. http://dx.doi.org/10.18203/2349-3291.ijcp20214940.
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Background: Iron deficiency anemia during pregnancy is a major health issue in India. However, the status of iron stores in infants born to iron depleted mothers remains controversial and inadequately investigated. The present study is therefore an attempt to understand whether maternal anemia and iron stores have any significant effect on iron status and growth of fetus.Methods: This is a prospective, cross-sectional, hospital based study conducted at Mata Chanan Devi Hosital, Janakpuri, New Delhi. Hemoglobin and iron profile of 100 newborns and their mothers were taken. Mothers were divided into anemic and non anemic group to see the effect of maternal anemia on fetus.Results: A total of 100 newborns and their mothers were analysed. Cord hemoglobin and iron profile was significantly reduced in anemic compared to non anemic group. Birth weight of newborn was significantly reduced only in moderately anemic group as compared to non anemic group but there was no difference seen in length and head circumference.Conclusions: Maternal serum ferritin levels should be measured for the diagnosis of occult iron deficiency in the fetus so that timely measures can be taken to prevent iron deficiency anemia in the newborn.
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Laffolie, Jan de, Martin W. Laass, Dietmar Scholz, Klaus-Peter Zimmer, Stephan Buderus, and CEDATA-GPGE Study Group. "Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE®." Gastroenterology Research and Practice 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/8424628.
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Aim. To determine the prevalence of anemia and its association with disease severity in children and adolescents with IBD. Methods. CEDATA-GPGE is a registry for pediatric patients with IBD in Germany and Austria from 90 specialized centers. As markers of disease severity, analysis included patient self-assessment on a Likert scale (1–5; 1 = very good) and physicians’ general assessment (0 = no activity to 4 = severe disease) and the disease indices. Anemia was defined as hemoglobin concentration below the 3rd percentile. Results. Prevalence of anemia was 65.2% in CD and 60.2% in UC. Anemic CD and UC patients showed significantly worse self-assessment than patients without anemia (average ± standard deviation; CD: 3.0 ± 0.9 versus 2.5 ± 0.9, p<0.0001; UC: 2.9 ± 0.9 versus 2.3 ± 0.9, p<0.0001). Accordingly, physicians’ general assessment (PGA) was significantly worse in anemic than in nonanemic patients in CD (p<0.0001) and UC (p<0.0001). PCDAI in anemic CD, p<0.0001, and PUCAI in anemic UC patients, p<0.0001, were significantly higher than in nonanemic patients. 40.0% of anemic CD and 47.8% of anemic UC patients received iron during follow-up. Conclusion. Almost 2/3 of pediatric IBD patients are anemic. Patients’ self-assessment and disease severity as determined by PGA and activity indices are worse in anemic patients. Contrastingly, only a minority received iron therapy.
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Akpinar, Cetin Kursad, Erdem Gurkas, and Emrah Aytac. "Moderate to Severe Anemia Is Associated with Poor Functional Outcome in Acute Stroke Patients Treated with Mechanical Thrombectomy." Interventional Neurology 7, no. 1-2 (October 11, 2017): 12–18. http://dx.doi.org/10.1159/000480642.
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Background: Anemia will negatively affect cerebral collaterals and penumbra. Eventually, it may cause worse clinical outcomes and even increase mortality rates in stroke patients. Anemia has recently been suggested to be an independent risk factor for ischemic stroke. Therefore, we aimed to investigate the effects of the presence of anemia on clinical outcomes in ischemic stroke patients undergoing mechanical thrombectomy. Methods: This was a retrospective study involving the prospectively and consecutively collected data of 90 adult patients between January 2015 and August 2016. Hemoglobin (Hb) cutoff levels were accepted as 12 g/dL for women and 13 g/dL for men. Patients having anemia were further divided into three subgroups as severe anemia (Hb <8 g/dL for both genders), moderate anemia (Hb <10 g/dL for both genders), and mild anemia (Hb <13 g/dL for men and Hb <12 g/dL for women). Results: Forty of the subjects (44.4%) had anemia. Moderate anemia was detected in 14 out of 90 patients (15.5%) and severe anemia was found in only four of them (4.4%). Poor functional outcome (mRS 3-6) was similar in both anemic and non-anemic patients (37.5% vs. 38%, respectively, p = 0.08), but poor functional outcome was found to be statistically significant with severe anemic group (Hb <8 mg/dL) (p = 0.003). In multiple logistic regression analysis, moderate and severe anemia has been found to increase the mortality (p = 0.032). Conclusions: Our study demonstrated a poor functional outcome only in moderate to severe anemic patients. Clinicians should keep in mind the negative effect of moderate to severe anemia in the clinical course of acute stroke patients treated with mechanical thrombectomy.
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Jonker, Sonnet S., Thomas D. Scholz, and Jeffrey L. Segar. "The effect of adrenalectomy on the cardiac response to subacute fetal anemia." Canadian Journal of Physiology and Pharmacology 89, no. 2 (February 2011): 79–88. http://dx.doi.org/10.1139/y10-108.
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The mechanisms that stimulate fetal heart growth during anemia are unknown. To examine the hypothesis that adrenal hormones contribute to this process, we determined the effects of adrenalectomy (Adx) on heart growth and the activation of cardiac mitogen-activated protein kinases (MAPKs) in the presence and absence of fetal anemia. To identify mechanisms contributing to the initiation of cardiac growth, the duration of anemia was limited to a period shorter than that previously described to result in increased cardiac mass. Four groups of fetal sheep were studied (Adx-Anemic, Adx-Control, Intact-Anemic, Intact-Control). Anemia was created by daily controlled hemorrhage for 5 days; hearts were collected for analysis at 133 d gestation (term 145 d). Cardiomyocyte morphometry, immunohistochemistry for Ki-67 (proliferation marker), and Western blotting for protein levels of MAPKs and proliferating cell nuclear antigen (PCNA) were performed. Blood pressure, heart rate, heart weight-to-body weight ratio, and cardiomyocyte length and width remained similar among groups throughout the study. PCNA levels in the Adx-Anemic group were twice as high as in any other group (both ventricles, p < 0.05). Levels of phosphorylated extracellular signal-regulated kinase (ERK) were ~60% higher in the Intact-Anemic and Adx-Anemic groups, compared with the Intact-Control and Adx-Control groups (p < 0.02). These results suggest that adrenal hormones may attenuate fetal cardiomyocyte proliferation in response to anemia (as evidenced by the increased PCNA in Adx-Anemic fetuses) and that phosphorylation of myocardial ERK results from fetal anemia, irrespective of the status of the fetal adrenal gland.
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Gupta Bansal, Priyanka, Gurudayal Singh Toteja, Neena Bhatia, Naval Kishore Vikram, Anupa Siddhu, Ashok Kumar Garg, and Ashok Kumar Roy. "Deficiencies of Serum Ferritin and Vitamin B12, but not Folate, are Common in Adolescent Girls Residing in a Slum in Delhi." International Journal for Vitamin and Nutrition Research 85, no. 1-2 (December 2015): 14–22. http://dx.doi.org/10.1024/0300-9831/a000219.
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Abstract. Anemia among adolescent girls is one of the major challenges faced by India. The present study was undertaken to assess the prevalence of anemia and status of other hematological parameters among adolescent girls (11 - 18 years) residing in an urban slum of Delhi. A total of 794 adolescent girls were recruited for the study. The prevalence of anemia was estimated using the cyanmethemoglobin method. Serum levels of ferritin, folic acid and vitamin B12 were estimated for anemic subjects. The prevalence of anemia was reported as 58.7 %, with 31.6 %, 25.7 % and 1.4 % of subjects being mild, moderate and severely anemic. Hemoglobin levels of subjects who had attained menarche were found to be significantly lower than those who had not attained menarche. The prevalence of serum ferritin, folic acid and vitamin B12 deficiency among those who were anemic was reported as 41.1 %, 5.0 % and 63.3 % respectively. A total of 23.5 % anemic subjects had concomitant micronutrient deficiencies of serum vitamin B12 and ferritin. The results indicate that supplemental iron and vitamin B12 may better address the burden of anemia in adolescent girls in Delhi.
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Rosing, Joanna L., Rami S. Komrokji, and E. Gordon Margolin. "Anemia in Elderly Hospitalized Veterans: Prevalence, Causes, and Clinical Impact." Blood 106, no. 11 (November 16, 2005): 3756. http://dx.doi.org/10.1182/blood.v106.11.3756.3756.
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Abstract Anemia occurs frequently in elderly and has been identified as a public health issue. The purpose of our study was to identify the prevalence, causes and clinical impact of anemia among hospitalized elderly veterans. We performed retrospective review of all medical records of patients 65 years or older admitted over 6-month period to the general internal medicine service at Cincinnati Veteran Medical Center. Anemia was defined according to WHO criteria (< 13.0 g/dl in males and < 12.0 g/dl in females). Data were collected reviewing the electronic medical records. Variables included demographics, functional status, reason of admission, co-morbidities, medications, hemoglobin level on admission, and selected laboratory results. Causes of anemia were identified from the medical records or interpretation of laboratory data. Outcome variables included duration of hospitalization, end-of-hospitalization death, re-admissions, and survival at the end of the study. Database was generated using SPSS software. Descriptive statistics were used to describe rate, and causes of anemia. Chi-square test was used to compare categorical variables between patients with anemia and patients with no anemia and t-test was used for continuous variables. Kaplan-Meier curves and Cox-regression analysis were used for survival analysis. Between January 2004-June 2004, 500 hundred patients 65 years or older were admitted to general medicine service. Mean age was 76 years. Majority of patients were males (97%) and white (71%). Coronary artery disease was the commonest identified reason for admission. Anemia was observed in 298 patients (59.6%) on admission. Mean hemoglobin level on admission was 12.2 +/− 2.39. The most common causes of anemia were iron deficiency anemia (25%), anemia of chronic disease/chronic renal disease 14%, blood loss 7%, vitamin B 12 deficiency (6%), Myelodysplastic syndrome (4%). Anemia was mutli-factorial in 10% of patients, 34% of patients had other causes of anemia or unknown cause. Baseline characteristics were similar between patients identified with anemia and non-anemic group except for race; where more Afro-American patients were in the anemia group 31% compared to 10 % in the non-anemic group (p-value < 0.0005). Malignancy, diabetes melitus, chronic renal failure, and cirrhosis were comorbidities more seen in the anemic group. There was no statistically significant difference between the anemic patients and non-anemic group regarding duration of hospitalization, re-admission, and end-of-hospitalization death rate. Survival was inferior among anemic patients within 6 month, 41% of patients died compared to 24% among non-anemic patients (Log Rank test, P value 0.0001) (Figure-1). Anemia was a statistically significant co-morbidity affecting survival among multivariable analysis using cox-regression analysis. This study is the first to address the high prevalence of anemia among hospitalized elderly veterans and suggests a clinical impact on survival. It raises questions to be better addressed in a prospective fashion. Figure Figure
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Oster, Howard S., Michael Hoffman, Eythan Cohen, and Moshe Mittelman. "Anemia in Congestive Heart Failure: The Anemia Is Common and Is Associated with More Severe CHF - Results of a National Survey." Blood 110, no. 11 (November 16, 2007): 3685. http://dx.doi.org/10.1182/blood.v110.11.3685.3685.
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Abstract Anemia has been recognized as a risk as well as a precipitating factor in ischemic heart disease, and in congestive heart failure (CHF). However, there are still open questions regarding the prevalence of anemia in CHF, and the severity and associated clinical manifestations of the anemic CHF patient. In order to characterize CHF in Israel, a national survey was conducted during the period March 1–April 30, 2004. Data were collected on all patients with CHF exacerbation admitted to 96 departments of medicine and 26 cardiology units throughout the country. In this study we have focused on anemia in CHF patients with a special emphasis on the differences observed between CHF patients with anemia (A group) and CHF patients with no anemia (NA group). Results: Of 2388 patients admitted for exacerbation of CHF, 1326 (55.5%) were found to have anemia (<13g/dl for men, <12g/dl women). Both A and NA groups had similar male/female ratio (57.2%/42.8% A vs 53.5%/46.5% NA). The anemic patients (A) tended to be older (74.8 yrs A vs 72.5 yrs NA, p=0.00001), to have more prior hospitalizations (2.0 A vs 1.3 NA, p=0.0001), and to suffer from a more severe CHF. For example, 49.3% of anemic vs only 41% of non-anemic patients were reported to have baseline New York Heart Association (NYHA) class III–IV. Most notably both in-hospital and six-month mortality rates were significantly higher among anemic CHF patients (in-hospital: 6.6% A vs 4.6% NA, p=0.039; six-month: 25% A vs 15% NA, p<0.00001). Interestingly, no difference was observed between the two groups in the percentage of CHF patients taking aspirin prior to admission. However, fewer anemic patients were discharged with aspirin (63.7% A vs 72.7% NA, p=0.00001). Conclusions: In this large survey of patients with CHF exacerbation, anemia was found to be common and the anemic patients were found to be older, to have more prior hospitalizations, more severe CHF (NYHA class III–IV), and higher in-hospital and six-month mortality rates. Because both groups had similar rates of aspirin usage, it may be suggested that aspirin plays no significant role in the development of anemia in such patients. Thus, the common practice of withholding this medication from anemic CHF patients may deserve reevaluation. Our data call for a prospective clinical trial, which will test the possibility that correction of the anemia (by RBC transfusion or recombinant erythropoietin) can improve the clinical outcome of the anemic CHF patient.
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Chen, Chong, Wenhui Zhou, Wenliang Fan, Xianying Ning, Shuai Yang, Ziqiao Lei, and Chuansheng Zheng. "Association of anemia and COVID-19 in hospitalized patients." Future Virology 16, no. 7 (July 2021): 459–66. http://dx.doi.org/10.2217/fvl-2021-0044.
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Aim: COVID-19 is a major threat to public health worldwide. A large proportion of COVID-19 patients is proved to develop anemia. Herein, we investigate the association between anemia and severe pneumonia. Materials & methods: 137 of COVID-19-confirmed patients admitted to Wuhan Union Hospital (Wuhan, China) from 13 February to 17 March 2020 were included. Their clinical characteristics and laboratory data were studied, and multivariable logistic regression analyses were performed. Results: The anemic patients were less likely to develop fever in the early stage of COVID-19. Elevated IL-6 levels were found in anemic COVID-19 patients compared with those without anemia. COVID-19 patients with anemia had an 8.2 times greater possibility of developing severe pneumonia compared with their counterparts without anemia. Conclusion: This study comprehensively describes the clinical characteristics of anemic patients with ordinary, severe and critical COVID-19 and demonstrates the close relationship between the anemia and severe COVID-19.
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Kumar, Anil, Mimoh Sharma, Mohammad Frayez, and Asna Rahman. "Behind the veil of anemia: Assessment of iron, folic acid, and vitamin B12 deficiencies and their association with red cell indices in anemic and non-anemic women." Indian Journal of Obstetrics and Gynecology Research 11, no. 2 (May 15, 2024): 172–77. http://dx.doi.org/10.18231/j.ijogr.2024.036.
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During pregnancy anemia is a common health issue with various factors influencing its occurrence. It is a major public health problem in India. It is believed that 2.36 billion individuals are affected globally, and it is also an endemic problem in India. Iron deficiency often leads to iron deficiency anemia (IDA), significantly influencing maternal and fetal health.This study aims to investigate the complete blood count and nutritional parameters including Iron profile, vitamin B12, and Folic acid in anemic and non-anemic participants.The study involved 458 women of which 300 were anemic women and 158 were non-anemic women, predominantly from rural areas. The severity of anemia was classified as per WHO guidelines. The CBC was estimated by a 3-part hematology analyzer Medonic M-series, while the iron profile, vitamin B12, and folic acid were measured by using an automated analyzer Abbott Architect 1000 SR.The severity of anemia among the anemic women, classified according to WHO guidelines, revealed that 38.7% had mild anemia, 32.7% had moderate anemia, and 28.6% had severe anemia. 39.3% women exhibited microcytic hypochromic cells, 38% had normocytic normochromic cells, and 22.7% exhibited macrocytic cells. 56.6% had iron deficiency, 10% had folate deficiency, 16.7% had vitamin B12 deficiency, 6.7% had iron+vitamin B12+folic acid deficiency and 10% had vitamin B12+folic acid deficiency. Based on the severity only vitamin B12 was significantly reduced in severe (145.65±58.43) than moderate (177.06±66.24) and mild group (174.43±68.43), p=0.042. Hemoglobin showed a positive correlation with iron level (r=0.523, p<0.0001), and a negative correlation with ferritin (r=-0.355, p<0.0001).: These findings provide valuable insights into the nutritional status of the anemic women and highlights the need for targeted interventions to address micronutrient deficiencies during pregnancy.
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Anderson, Katie L., Adam Birkenheuer, George E. Moore, and Allison Kendall. "A retrospective study of vector borne disease prevalence among anemic dogs in North Carolina." PLOS ONE 18, no. 11 (November 8, 2023): e0293901. http://dx.doi.org/10.1371/journal.pone.0293901.
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Background Anemia is an important cause of morbidity and mortality in dogs. Further understanding of the prevalence of vector borne diseases (VBD) in anemic dogs is needed. Objectives The objective of this retrospective study was to describe the rate of exposure to or infection with VBD among anemic dogs presented to a teaching hospital in North Carolina and to further characterize the anemia in dogs with VBD exposure. Animals A total of 597 anemic dogs that were concurrently tested for VBD were examined at a referral veterinary hospital between January 2012 and December 2018. Methods Retrospective descriptive study. Demographic, clinicopathologic, and VBD testing data were obtained from medical records. Results Of the 597 anemic dogs examined, 180 (30.15%; 95% CI: 26.49–34.01%) tested positive for one or more VBD. There was no difference in the severity of anemia or the proportion of dogs displaying a regenerative anemia between dogs testing positive and negative for VBD. Conclusions A large proportion of anemic dogs from this region test positive for exposure to or infection with VBD. Our study supported the use of PCR and serology run in parallel to maximize the chance of detecting exposure to or infection with VBD compared to either serology or PCR alone. At this time, it is unknown whether infection with VBD contributed to the development of anemia in these patients. However, given the prevalence of VBD exposure in anemic dogs, testing for VBD in anemic patients from this region of the United States is warranted.
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Sari, Marlynda Happy Nurmalita, and Dina Dewi Anggraini. "Penyuluhan dan Deteksi Dini Anemia menuju Generasi Berkualitas pada Mahasiswa Kebidanan." jurnalempathy.com 1, no. 1 (July 30, 2020): 72–84. http://dx.doi.org/10.37341/jurnalempathy.v1i1.13.
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Background: The prevalence of anemia in adolescent girls in Indonesia is still high at 57.1%. As a result of anemia is adolescent learning achievement can decrease, work productivity decreases and body immunity decreases so that the body is easily infected. Long-term effects of anemia in adolescent girls can occur complications of pregnancy and even the risk of maternal and perinatal death. Purpose of this studi is provide counseling and early detection of anemia to Midwifery students as an effort to make them aware in preventing and overcoming anemia. Methods: The target of this activity is 132 students of the Blora Midwifery Diploma Program. This activity is carried out by providing information or knowledge in the form of counseling to students about anemia and followed by history and physical examination. Only students who showed signs and symptoms of anemia who were tested for HB levels were 30 students. Results: Early detection of 30 students there were 53.3% who were not anemic and 46.7% were anemic. Most of the students' menstruation period is 6-7 days which is 73.3%. While the results of counseling some students already understand about anemia. Conclusion: Of the 132 students only 30 showed signs and symptoms of anemia. Hb examination results are almost the same between respondents who are anemic and not anemic. It is hoped that the results of community service activities can be used as an illustration of the incidence of anemia in Midwifery students so that efforts can be made to prevent and manage anemia. Provide motivation and awareness to students to consume nutritious and iron-containing foods or to consume extra blood tablets.
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Wang, Lei, Mengjie Li, Sarah-Eve Dill, Yiwei Hu, and Scott Rozelle. "Dynamic Anemia Status from Infancy to Preschool-Age: Evidence from Rural China." International Journal of Environmental Research and Public Health 16, no. 15 (August 2, 2019): 2761. http://dx.doi.org/10.3390/ijerph16152761.
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Anemia is a serious nutritional deficiency among infants and toddlers in rural China. However, it is unclear how the anemia status changes among China’s rural children as they age. This study investigates the prevalence of anemia as children grow from infancy to preschool-age, as well as the dynamic anemia status of children over time. We conducted longitudinal surveys of 1170 children in the Qinba Mountain Area of China in 2013, 2015 and 2017. The results show that 51% of children were anemic in infancy (6–12 months), 24% in toddlerhood (22–30 months) and 19% at preschool-age (49–65 months). An even larger share of children (67%) suffered from anemia at some point over the course of study. The data also show that although only 4% of children were persistently anemic from infancy to preschool-age, 8% of children saw their anemia status deteriorate. We further found that children may be at greater risk for developing anemia, or for having persistent anemia, during the period between toddlerhood and preschool-age. Combined with the finding that children with improving anemia status showed higher cognition than persistently anemic children, there is an urgent need for effective nutritional interventions to combat anemia as children grow, especially between toddlerhood and preschool age.
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Ali, Usman, Shahid Rizwan Safir, Bakhti Mahmood, Shah Umam, Abdul Quddos, and Raza Muhammad Khan. "Analyzing the Relationship Between Anemia and Diabetic (Foot Ulcer) at Department of Medicine KTH Peshawar a Cross-Sectional Study." Pakistan Journal of Medical and Health Sciences 17, no. 2 (March 15, 2023): 806–7. http://dx.doi.org/10.53350/pjmhs2023172806.
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Diabetes complications like diabetic (foot ulcer) (DFU) are frequent and may be incapacitating. Patients with diabetes who have anemia have a higher chance of developing DFU. Objectives: To analyze the relationship between anemia and DFU in the patients. Methods: This study was carried out at the department of Medical Unit Khyber Teaching Hospital from 1st March 2022 to 31st March 2023 in Pakistan. Sample size 50 All patients with diabetes and DFU were included. The following demographic, clinical, and laboratory parameters were compared between patients with and without anemia ( age, sex, body mass index) (BMI), type of diabetes, duration of diabetes, glycosylated hemoglobin (HbA1c), and serum ferritin levels. Results: The study comprised 90 participants with both diabetes and DFU. 39 (43.3%) of these individuals had anemia. There was no significant difference in the [mean age] (p=0.664), [sex] (p=0.392),[ BMI] (p=0.532), type of diabetes (p=0.505), duration of diabetes (p=0.084), and HbA1c (p=0.194) between the [anemic and non-anemic] patients. However, the (mean serum ferritin levels) were significantly lower in anemic patients compared with non-anemic patients [p<0.001]. Conclusion: Lower serum ferritin levels are linked to anemia, a prevalent complication in DFU patients. To assess the involvement of anemia in the onset and course of DFU, further research is required. Keywords: Anemia, Diabetic, Foot Ulcer, Department of Medicine, KTH Peshawar, Cross-Sectional Study.
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Kumari, Anita, Sanjeet Kumar Singh, Ravi Shekhar, and Swati Mittal. "A STUDY OF LIPID PROFILE IN ANAEMIA." International Journal of Advanced Research 10, no. 02 (February 28, 2022): 572–75. http://dx.doi.org/10.21474/ijar01/14240.
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Objectives:Both anemia and dyslipidemia are widely prevalent public health problems, especiallyin the Indian population. Associationof anemia and dyslipidemias were reported in some individual experimental animals. The study was planned to find thechanges in serum lipid profile in adult Indian patients with anemia. Material and methods:100 cases of anemia (hemoglobin <13 g% in men and <12 g% in women), and 100 age and sex matched healthy controls, in the age group 18-40 years were investigated for any possible changes in serum lipid profile i.e.,triglycerides, total cholesterol, high density lipoprotein cholesterol, very low density lipoprotein cholesterol. Results:The mean cholesterol in patients with anemia was 122.47 ± 29.32 mg/dl, whereas in controls group was 160.43 ± 38.91 mg/dl. The mean serum triglyceride level in patients with anemia was 89.41 ± 33.1532 mg/dl and in control group was 111.45 ± 40.6632 mg/dl. Mean high-density lipoprotein levels were 36.13 ± 12.8132 mg/dl in anemic group and 45 ± 13.032 mg/dl in control group, whereas low-density lipoprotein (LDL) cholesterol level was 70.12 ± 21.64 mg/dl in the anemic group and 100.45 ± 30.8032 mg/dl in control group. VLDL levels were higher in control group (21.96 ± 8.132 mg/dl) compared to the anemic group (18.34 ± 7.6432 mg/dl). Conclusion: Lipoproteins levels were significantly abnormal in anemic as compared to non-anemic subjects.
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Ouzennou, Nadia, Hakima Amor, and Abdellatif Baali. "Socio-economic, cultural and demographic profile of a group of Moroccan anaemic pregnant women." African Health Sciences 19, no. 3 (November 6, 2019): 2654–59. http://dx.doi.org/10.4314/ahs.v19i3.41.
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Background: Anemia is a major public health problem in Morocco especially among vulnerable groups including pregnant women. Several studies have confirmed that anemia is associated with demographic, socioeconomic and cultural factors.Objective: The objective of this study is to describe the socioeconomic, cultural and demographic profile of a group of anemic pregnant women and to determine the conditions influencing the development of anemia in the Moroccan contextMethods: A retrospective cross-sectional study was conducted by structured interview among a group of Moroccan pregnant women (300 of anemic women and 425 of non-anemic). Data were collected on biodemographic and socio-economic variables, the socio-cultural conditions of the women, the characteristics of the pregnancy and information relating to anemia.Results: Using the WHO classification criterion according to the severity of anemia, 40.6%, 56.6% and 2.8% of anaemic women were respectively mildly, moderately and severely anemic. Primiparity, unemployment, lower socio-economic level and illiteracy, were found to be associated with the development of anemia in pregnant women.Conclusion: In Morocco, nutritional problems hamper human development and improvement of health status. Knowledge of the strictness of deficiencies and factors associated are necessary to develop adapted strategies intervention to the national context.Keywords: Anemia, pregnant women, socioeconomic factors, Morocco.
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Saeed, Muhammad, Iftikhar Ahmed Siddiqui, Asher Fawwad, Anum Butt, Kahkashan Perveen, Ruqaya Nangrejo, and Abdul Basit. "Effect of anemia on HbA1c level in subjects with normal glucose tolerance." Professional Medical Journal 28, no. 08 (August 1, 2021): 1172–77. http://dx.doi.org/10.29309/tpmj/2021.28.08.6121.
Full textAbstract:
Objective: To evaluate the effect of iron deficiency anemia (IDA) on HbA1c levels in non-diabetic Pakistani individuals. Study Design: Observational Study. Setting: Baqai Institute of Diabetology and Endocrinology, Baqai Medical University Karachi. Period: March 2019 to May 2019. Material & Methods: After approval by the ethics committee of BMU. A world Health Organization (WHO) criterion was used for screening normal glucose tolerance. Subject with type 1 and 2 diabetes, and gestational diabetes were excluded. Selected subjects were categorized into 2 groups (anemic and non-anemic). Data was collected on a structured questionnaire. Result: Out of 139 subjects, 72 were males and 67, were females. Anemia was more common in males as compared to females (34.7% vs 19.4%). Among males, HbA1c level was found higher in anemic subjects with MCV<76fl than anemic subjects with MCV>76fl and subjects without anemia. While in females, HbA1c level was similar in both anemic and non-anemic subjects. Conclusion: HbA1c as a diagnostic marker should be assessed carefully as the presence of IDA can lead to falsely elevated HbA1c levels in non-diabetic subjects.