Relevant bibliographies by topics / Analgesics Administration

Academic literature on the topic 'Analgesics Administration'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Analgesics Administration"

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Sekulovski, M., B. Simonska, G. Mutafov, V. Alexandrov, and L. Spassov. "Bilateral ultrasound-guided abdominal peripheral block in tap plane, tap - block." Trakia Journal of Sciences 18, no. 4 (2020): 344–49. http://dx.doi.org/10.15547/tjs.2020.04.009.

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INTRODUCTION: Bilateral ultrasound-guided peripheral block (TAP - block) in the plane between the inner oblique abdominal muscle and the transversal abdominal muscle – TAP plane, is a regional anesthesia technique by infiltration of a local anesthetic, provides analgesia for operations involving the anterior abdominal wall. The analgesic effectiveness of the block decreases the consumption of opioid analgesics and non-steroidal anti-inflammatory drugs. AIM: In this study, we evaluated the intraoperative analgesic efficacy of bilateral TAP - block and the consumption of opioid analgesics in patients undergoing bilateral laparoscopic inguinal hernia repair. METHODS: The study was conducted with 35 patients, who were randomized into two groups. In the control group (group I), there are patients who received general anesthesia (GA), and experimental group (group II), were patients who have received general anesthesia and a bilateral tap block (GA + TAP). RESULTS: Patients with TAP-block (group II) have significantly lower fentanyl consumption compared to group I. CONCLUSION: Multimodal approach for the simultaneous administration of general anesthesia with a TAP block provides effective intraoperative analgesia and significantly reduces the perioperative consumption of opioid analgesics.
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Bayalieva, Aynagul Zh, and J. N. Yankovich. "BIOAVAILABILITY AND EFFICACY OF OPIOID USE WITH EPIDURAL BLOCKADE." Regional Anesthesia and Acute Pain Management 12, no. 2 (June 15, 2018): 76–81. http://dx.doi.org/10.18821/1993-6508-2018-12-2-76-81.

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The article is devoted to the questions of epidural analgesia with the use of opioid analgesics. The work analyzes the clinical effectiveness of epidural use of opioids, lists possible complications and cautions of this method of anesthesia. Bioavailability of morphine and fentanyl for the spinal cord with epidural administration allows to achieve analgesic effects at a certain block level more effectively than with systemic administration. However, the side effects of opioids in the form of respiratory depression are also found with epidural administration (3%), so patient safety monitoring is necessary.
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Whitley, Gregory Adam, and Richard Pilbery. "Pre-hospital intranasal analgesia for children suffering pain: a rapid evidence review." British Paramedic Journal 4, no. 3 (December 1, 2019): 24–34. http://dx.doi.org/10.29045/14784726.2019.12.4.3.24.

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Introduction: Pre-hospital analgesic treatment of injured children is suboptimal, with very few children in pain receiving analgesia. Studies have identified a number of barriers to pre-hospital pain management in children which include the route of analgesia administration. The aim of this review is to critically evaluate the pre-hospital literature, exploring the safety and efficacy of intranasal (IN) analgesics for children suffering pain.Methods: We performed a rapid evidence review, searching from inception to 17 December 2018, CINAHL, MEDLINE and Google Scholar. We included studies of children < 18 years suffering pain who were administered any IN analgesic in the pre-hospital setting. Our outcomes were effective pain management, defined as a pain score reduction of ≥ 2 out of 10, safety and rates of analgesia administration. Screening and risk of bias assessments were performed in duplicate. We performed a narrative synthesis.Results: From 310 articles screened, 23 received a full-text review resulting in 10 articles included. No interventional studies were found. Most papers reported on the use of intranasal fentanyl (INF) (n = 8) with one reporting IN ketamine and the other IN S-ketamine. Narrative synthesis showed that INF appeared safe and effective at reducing pain; however, its ability to increase analgesia administration rates was unclear. The effectiveness, safety and ability of IN ketamine and S-ketamine to increase analgesia administration rates were unclear. There was no evidence for IN diamorphine for children in this setting.Conclusion: Interventional studies are needed to determine with a higher confidence the effectiveness and safety of IN analgesics (fentanyl, ketamine, S-ketamine, diamorphine) for children in the pre-hospital setting.
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Kircher, Janeva, Amy L. Drendel, Amanda S. Newton, Sukhdeep Dulai, Ben Vandermeer, and Samina Ali. "Pediatric musculoskeletal pain in the emergency department: a medical record review of practice variation." CJEM 16, no. 06 (November 2014): 449–57. http://dx.doi.org/10.1017/s1481803500003468.

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ABSTRACTObjective:Musculoskeletal (MSK) injuries are a common, painful pediatric presentation to the emergency department (ED). The primary objective of this study was to describe current analgesic administration practices for the outpatient management of children’s MSK pain, both in the ED and postdischarge.Methods:We reviewed the medical records of consecutive pediatric patients evaluated in either a pediatric or a general ED (Edmonton, Alberta) during four evenly distributed calendar months, with a diagnosis of fracture, dislocation, strain, or sprain of a limb. Abstracted data included demographics, administered analgesics, pain scores, discharge medication advice, and timing of clinical care.Results:A total of 543 medical records were reviewed (n 5 468 pediatric ED, n 5 75 general ED). Nineteen percent had documented prehospital analgesics, 34% had documented in-ED analgesics, 13% reported procedural sedation, and 24% documented discharge analgesia advice. Of those children receiving analgesics in the ED, 59% (126 of 214) received ibuprofen. Pain scores were recorded for 6% of patients. At discharge, ibuprofen was recommended to 47% and codeine-containing compounds to 21% of children. The average time from triage to first analgesic in the ED was 121 6 84 minutes.Conclusions:Documentation of the assessment and management of children’s pain in the ED is poor, and pain management appears to be suboptimal. When provided, ibuprofen is the most common analgesic used for children with MSK pain. Pediatric patients with MSK pain do not receive timely medication, and interventions must be developed to improve the ‘‘door to analgesia’’ time for children in pain.
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Kumar, Govindaraj Padmanabha, Chew Shu-Lyn, Goi Ee Win, Lee Win Sie, Nur Fatin Khaleeda binti Lakman, and Nazmul Haque. "Comparison between preoperative and post-operative administration of paracetamol, ibuprofen and mefenamic acid for post-extraction pain control." Biomedical Research and Therapy 7, no. 5 (May 25, 2020): 3794–98. http://dx.doi.org/10.15419/bmrat.v7i5.606.

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Pain is a common aftereffect following a dental treatment, especially extractions. Hence, the main aim of the study was to compare the effect of pre-operative and post-operative analgesic usage on post-operative pain management following dental treatment. Moreover, the efficacies of three types of painkillers (Paracetamol, Ibuprofen and Mefenamic Acid) in pain relief were also evaluated. Volunteers (n = 120) who were undergoing extraction participated in this study and were randomly divided into two groups. One group consisting of 60 participants were given pre- and post-operative analgesics while another group (n = 60) received post-operative analgesics only. A visual scale was used to record pain from zero to 56 hours post-operatively at 8-hour intervals. The results showed that patients who were taking analgesics pre-operatively experienced significantly (p = 0.0045) less pain compared to those who had taken post-operative analgesics only However, a lower cumulative number of moderate and severe experiences of post-extraction pain was recorded for the pre- and post-operative analgesic treatment groups as compared to the postoperative only analgesic treatment group; no significant differences were observed. Moreover, no significant differences were observed among the analgesics used in this study as well. On the basis of these results, we conclude that preoperative analgesic usage has a positive impact on postextraction acute pain management.
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Smith, Howard. "Peripherally-Acting Opioids." Pain Physician 2s;11, no. 3;2s (March 14, 2008): S121—S132. http://dx.doi.org/10.36076/ppj.2008/11/s121.

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Opioids are broad-spectrum analgesics with potent pain-relieving qualities but also with potential adverse effects related to both short-term and long-term therapy. Researchers have attempted to alter existing opioid analgesics, utilize different routes/ formulations, or combine opioid analgesics with other compounds in efforts to improve analgesia while minimizing adverse effects. Exogenous opioids, administered in efforts to achieve analgesia, work by mimicking the actions of endogenous opioids. Endogenous opioids and their receptors are located in the brain (supraspinal areas), spinal cord, and periphery. Although opioids and opioid receptors in the brain and spinal cord have received much attention over many years, peripheral endogenous opioid analgesic systems have only been extensively studied during the past decade. It has been known since 1990 that following injection into the rodent hindpaw, d-Ala2 , N-Me-Phe4 , Gly5 -ol-enkephalin (DAMGO) [a muopioid receptor agonist] probably exerts its antinociceptive effects locally, since the doses administered are too low to have an effect in the central nervous system (CNS). This notion has been supported by the observation that the quaternary compound morphine methyliodide, which does not as readily cross the bloodbrain barrier and enter the CNS, produced antinociception following intradermal administration into the hindpaw, but not when the same dose was administered systemically (subcutaneously at a distant site). With a growing appreciation of peripheral endogenous opioids, peripheral endogenous opioid receptors, and peripheral endogenous opioid analgesic systems, investigators began growing hopeful that it may be possible to achieve adequate analgesics while avoiding unwanted central untoward adverse effects (e.g. respiratory depression, somnolence, addiction). Peripherally-acting opioids, which capitalize on peripheral endogenous opioid analgesic systems, may be one potential future strategy which may be utilized in efforts to achieve potent analgesia with minimal side effects. Key words: Pain, opioids, immune cells, peripherally-acting opioids (PAO), leukocytes, inflammatory pain, peripheral analgesia
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Vincent Y.T. Cheung. "Pain experience during first trimester medical termination of pregnancy: Clinical observation from a cohort of Asian women." World Journal of Advanced Research and Reviews 13, no. 3 (March 30, 2022): 022–24. http://dx.doi.org/10.30574/wjarr.2022.13.3.0199.

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Objective: Optimal pain management during medical termination of pregnancy (TOP) remains unclear. This study aimed to suggest practical points to help minimize the intensity of pain of women during first trimester medical TOP. Methods: A retrospective observational study which reviewed the pain experience and the need for analgesics of 44 Asian women, who underwent first trimester medical TOP. Results: Nulliparous women had higher pain scores and more likely to need analgesics than multiparous women. Most women requested analgesics between 87.8 and 154.4 min (95% confidence interval) after misoprostol administration. Conclusions: Prophylactic analgesics should be provided to all nulliparous women undergoing first trimester medical TOP; and if paracetamol is the analgesic of choice, it should be given one hour after vaginal misoprostol administration to optimize pain relief.
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Bernadeth, Bernadeth, Ezra Oktaliansah, and Indriasari Indriasari. "Efektivitas Analgesik Pascaoperasi pada Pasien Pediatrik di Ruang Pemulihan Rumah Sakit Dr. Hasan Sadikin Bandung Periode Juni–November 2018." Jurnal Anestesi Perioperatif 7, no. 1 (April 30, 2019): 68–84. http://dx.doi.org/10.15851/jap.v7n1.15647.

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Nyeri merupakan pengalaman sensorik dan emosional yang tidak menyenangkan. Penyebab utama nyeri akut pada anak adalah prosedur pembedahan, trauma, dan penyakit akut. Penilaian nyeri merupakan bagian penting dari manajemen nyeri. Penelitian ini bertujuan mengetahui efektivitas analgesik pascaoperasi pada pasien pediatrik di ruang pemulihan RSUP Dr. Hasan Sadikin Bandung periode Juni-November 2018. Penelitian menggunakan metode deskriptif observasional prospektif terhadap 471 pasien pediatrik pascaoperasi di ruang pemulihan. Subjek penelitian dikelompokkan berdasar atas jenis operasi yang menyebabkan nyeri ringan, sedang, dan berat. Jenis analgesik pascaoperasi yang diberikan dan penilaian nyeri selama di ruang pemulihan dicatat untuk melihat efektivitas analgesik pascaoperasi tersebut. Dari hasil penelitian efektivitas analgesik pascaoperasi pada jenis operasi nyeri ringan sebanyak 181 pasien (99,5%), jenis operasi nyeri sedang sebanyak 231 pasien (98,7%), dan pada jenis operasi nyeri berat sebanyak 53 pasien (96,4%). Simpulan penelitian ini adalah efektivitas analgesik pascaoperasi pada pasien pediatrik di RSUP Dr. Hasan Sadikin Bandung masih kurang efektif karena belum memenuhi target rumah sakit 100% bebas nyeri dan pemberian analgesik juga belum efisien karena masih banyak terdapat ketidaksesuaian antara pilihan analgesik dan derajat nyeri.Effectiveness of Post-Operative Analgesia on Pediatric Patients in the recovery room of Dr. Hasan Sadikin General Hospital Bandung from June to November 2018Pain is an unpleasant sensory and emotional experience. Pain assessment is an important part of pain management. The main causes of acute pain in children are surgical procedures, trauma, and acute diseases. This study aimed to study the effectuIveness of postoperative analgesics in pediatric patients in the recovery room of Dr. Hasan Sadikin General Hospital Bandung from June to November 2018. This was a prospective observational descriptive study on 471 postoperative pediatric patients in recovery rooms. The research subjects were grouped based on the type of surgery pain, i.e. mild, moderate, and severe. The type of postoperative analgesics given and assessment of pain during the stay in the recovery room were recorded to see the effectiveness of the postoperative analgesic drug. From the results of the study it was identified that the of postoperative analgesics was effective for 181 patients (99.5%) in the mild pain surgery group, for 231 patients (98.7%) in the moderate pain surgery, and for 53 patients (96.4%) in severe pain surgery. It is concluded that the postoperative analgesics provided to pediatric patients at Dr. Hasan Sadikin General Hospital Bandung is still less effective because it has not met the target of 100% pain free set by the hospital and that analgesic administration is also not efficient because there are still many discrepancies in analgesic choices and the degree of pain.
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Tahereh Mohammadi, Elham Sharafi, Atieh Sadeghniiat-Haghighi, Farzan Vahedifard, Arghavan Shafiee-Aghdam, and Mohammad Arbabi. "Opioid for in-hospital admitted patient analgesics; which demographics and psychiatric profiles need more pain drugs?" World Journal of Biology Pharmacy and Health Sciences 11, no. 1 (July 30, 2022): 038–49. http://dx.doi.org/10.30574/wjbphs.2022.11.1.0090.

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Introduction: The prevalence of substance use disorders is higher in patients receiving opioid analgesics, and pain management in these patients is more challenging. This study aimed to investigate the pattern of analgesic drug administration and evaluate the associated factors. Method: The cross-sectional study was performed on 230 patients admitted to General Hospital ( internal medicine, surgery, and cancer wards). Result: The most used analgesic drug was morphine (59.4%), and a mean dose of 27 mg, then pethidine and methadone. Most pain control methods were intravenous (68.1%) and PRN pattern (61.1%). Using analgesics in patients who do not have risk factors for drug abuse, or addiction, can be considered safe. In our subjects, 95.6% of analgesic users did not become addicted or had any misuse. Discussion and Conclusion: For effective and low-risk treatment of these patients, there is a need for clinical skills, knowledge of opioid administration, assessment, and risk management of substance abuse and addiction. In patients with substance abuse, analgesics should be prescribed in a particular setting, under supervision, and with careful monitoring. Structured and planned administration of opioid agonists (such as methadone or buprenorphine) seems appropriate according to a structured schedule. These plans are recommended: · Increasing the awareness of clinicians about prescribing narcotic analgesics. · Prescribing narcotic analgesics with a regular pattern against PRN. · Evaluating patients for a history of substance abuse. · Closely monitoring them, and if necessary. · Counseling. Identifying high-risk groups such as women, youth, and psychiatric patients are also recommended, and performing early interventions.
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Saraghi, Mana, and Elliot V. Hersh. "Three Newly Approved Analgesics: An Update." Anesthesia Progress 60, no. 4 (December 1, 2013): 178–87. http://dx.doi.org/10.2344/0003-3006-60.4.178.

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Abstract Since 2008, three new analgesic entities, tapentadol immediate release (Nucynta) diclofenac potassium soft gelatin capsules (Zipsor), and bupivacaine liposome injectable suspension (EXPAREL) were granted US Food and Drug Administration (FDA) approval to treat acute pain. Tapentadol immediate-release is a both a mu-opioid agonist and a norepinephrine reuptake inhibitor, and is indicated for the treatment of moderate to severe pain. Diclofenac potassium soft gelatin capsules are a novel formulation of diclofenac potassium, which is a nonsteroidal anti-inflammatory drug (NSAID), and its putative mechanism of action is through inhibition of cyclooxygenase enzymes. This novel formulation of diclofenac allows for improved absorption at lower doses. Liposomal bupivacaine is a new formulation of bupivacaine intended for single-dose infiltration at the surgical site for postoperative analgesia. Bupivacaine is slowly released from this liposomal vehicle and can provide prolonged analgesia at the surgical site. By utilizing NSAIDs and local anesthetics to decrease the transmission of afferent pain signals, less opioid analgesics are needed to achieve analgesia. Since drug-related adverse events are frequently dose related, lower doses from different drug classes may be employed to reduce the incidence of adverse effects, while producing synergistic analgesia as part of a multimodal analgesic approach to acute pain.
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Dissertations / Theses on the topic "Analgesics Administration"

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Gregg, Elizabeth Dowing. "The relationship between analgesics administration and postoperative independence /." Staten Island, N.Y. : [s.n.], 1990. http://library.wagner.edu/theses/nursing/1990/thesis_nur_1990_gregg_relat.pdf.

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Persson, Jan. "Low dose ketamine : analgesia and side-effects in patients and volunteers /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3641-2/.

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Harmer, Michael. "The optimal mode of administration of traditional opioid analgesics for the relief of postoperative pain." Thesis, Queen Mary, University of London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300572.

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Eriksson-Mjöberg, Marianne. "Intravenous morphine after gynecological surgery : pain relief, endocrine and immune response /." Stockholm, 1997. http://diss.kib.ki.se/1997/19971107erik.

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Plesan, Aida. "Genetic factors and the role of the NMDA receptor in pain modulation and the effect of opioids /." Huddinge, 2000. http://diss.kib.ki.se/2000/91-628-4005-3/.

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Mamet, Wendy Ellen. "An examination of how critical care nurses' knowledge, attitudes, and concerns impact their administration of opoid analgesics /." Staten Island (M.S.) -- Wagner College, N.Y. : [s.n.], 1995. http://library.wagner.edu/theses/nursing/1995/thesis_nur_1995_mamet_exami.pdf.

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Crow, Lauren. "A Randomized Controlled Trial Comparing Preemptive Versus On Demand Administration of Analgesics After Mohs Surgery and Cutaneous Reconstruction." Thesis, The University of Arizona, 2016. http://hdl.handle.net/10150/603591.

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A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.
BACKGROUND: Mohs Micrographic Surgery (MMS) affords a high cure rate for cutaneous carcinoma. OBJECTIVE: This study was designed to characterize the pain patients experience after MMS and reconstruction of the head and neck, and to determine if preemptive dosing of analgesics was superior to patient‐initiated dosing on an "as needed" basis. METHODS: A controlled trial of 200 subjects undergoing MMS and reconstruction of skin cancers on the head and neck were randomized to either receive acetaminophen at the time of discharge or to take it on an "as needed" basis. The two groups were evaluated for differences in peak pain, satisfaction with pain management, and the need for narcotic analgesic "rescue" postoperatively. RESULTS: Peak pain levels after surgery were surprisingly low and rated, on average, 2/10 using an analog pain scale. Peak pain occurred at four hours postoperatively for both subgroups and patients were satisfied with pain control 72.5% of the time. There was no significant difference in any of the parameters between the two dosing regimens. CONCLUSIONS: Mohs surgery peak pain typically occurs four hours postoperatively. Patient satisfaction with pain management was high with acetaminophen regardless of the dosing regimen. Preemptive analgesia with acetaminophen does not appear to be superior to "asneeded" regimens.
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Pimentel, Camilla B. "Use of Opioids for Pain Management in Nursing Homes: A Dissertation." eScholarship@UMMS, 2015. https://escholarship.umassmed.edu/gsbs_diss/773.

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Nursing homes are an essential yet understudied provider of cancer-related care for those with complex health needs. Nine percent of nursing home residents have a cancer diagnosis at admission, and it is estimated that one-third of them experience pain on a daily basis. Although pain management is an essential component of disease treatment, few studies have evaluated analgesic medication use among adults with cancer in this setting. Use of opioids, which are the mainstay of pain management in older adults because of their effectiveness in controlling moderate to severe pain, may be significantly related to coverage by the Medicare Part D prescription drug benefit. However, little is known about Medicare Part D’s effects on opioid use in this patient population. A limited body of evidence also suggests that despite known risks of overdose and respiratory depression in opioid-naïve patients treated with long-acting opioids, use of these agents may be common in nursing homes. This dissertation examined access to appropriate and effective pain-related health care services among US nursing home residents, with a special focus on those with cancer. Objectives of this dissertation were to: 1) estimate the prevalence, and identify resident-level correlates, of pain and receipt of analgesic medications; 2) use a quasi-experimental research design to examine the relationship between implementation of Medicare Part D and changes in the use of fentanyl patches and other opioids; and 3) to estimate the prevalence, and identify resident-level correlates, of naïve initiation of long-acting opioids. Data on residents’ health status from the Resident Assessment Instrument/Minimum Data Set (versions 2.0 and 3.0) were linked with prescription drug transaction data from a nationwide long-term care pharmacy (January 2005–June 2007) and the Centers for Medicare and Medicaid Services (January–December 2011). From 2006 to 2007, more than 65% of residents of nursing homes throughout the US with cancer experienced pain (28.3% on a daily basis), among whom 13.5% reported severe pain. More than 17% of these residents who experienced daily pain received no analgesics (95% confidence interval [CI]: 16.0–19.1%), and treatment was negatively associated among those with advanced age, cognitive impairment, feeding tubes, and restraints. These findings coincided with changing patterns in opioid use among residents with cancer, including relatively abrupt 10% and 21% decreases in use of fentanyl patches and other strong opioids, respectively, after the 2006 implementation of Medicare Part D. In the years since Medicare Part D was introduced, some treatment practices in nursing homes have not been concordant with clinical guidelines for pain management among older adults. Among a contemporary population of long-stay nursing home residents with and without cancer, 10.0% (95% CI: 9.4–10.6%) of those who began receiving a long-acting opioid after nursing home admission had not previously received opioid therapy. Odds of naïve initiation of these potent opioids were increased among residents with terminal prognosis, functional impairment, feeding tubes, and cancer. This dissertation provides new evidence on pharmaceutical management of pain and on Medicare Part D’s impact on opioid use in nursing home residents. Results from this dissertation shed light on nursing home residents’ access to pain-related health care services and provide initial directions for targeted efforts to improve the quality of pain treatment in nursing homes.
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Pimentel, Camilla B. "Use of Opioids for Pain Management in Nursing Homes: A Dissertation." eScholarship@UMMS, 2004. http://escholarship.umassmed.edu/gsbs_diss/773.

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Nursing homes are an essential yet understudied provider of cancer-related care for those with complex health needs. Nine percent of nursing home residents have a cancer diagnosis at admission, and it is estimated that one-third of them experience pain on a daily basis. Although pain management is an essential component of disease treatment, few studies have evaluated analgesic medication use among adults with cancer in this setting. Use of opioids, which are the mainstay of pain management in older adults because of their effectiveness in controlling moderate to severe pain, may be significantly related to coverage by the Medicare Part D prescription drug benefit. However, little is known about Medicare Part D’s effects on opioid use in this patient population. A limited body of evidence also suggests that despite known risks of overdose and respiratory depression in opioid-naïve patients treated with long-acting opioids, use of these agents may be common in nursing homes. This dissertation examined access to appropriate and effective pain-related health care services among US nursing home residents, with a special focus on those with cancer. Objectives of this dissertation were to: 1) estimate the prevalence, and identify resident-level correlates, of pain and receipt of analgesic medications; 2) use a quasi-experimental research design to examine the relationship between implementation of Medicare Part D and changes in the use of fentanyl patches and other opioids; and 3) to estimate the prevalence, and identify resident-level correlates, of naïve initiation of long-acting opioids. Data on residents’ health status from the Resident Assessment Instrument/Minimum Data Set (versions 2.0 and 3.0) were linked with prescription drug transaction data from a nationwide long-term care pharmacy (January 2005–June 2007) and the Centers for Medicare and Medicaid Services (January–December 2011). From 2006 to 2007, more than 65% of residents of nursing homes throughout the US with cancer experienced pain (28.3% on a daily basis), among whom 13.5% reported severe pain. More than 17% of these residents who experienced daily pain received no analgesics (95% confidence interval [CI]: 16.0–19.1%), and treatment was negatively associated among those with advanced age, cognitive impairment, feeding tubes, and restraints. These findings coincided with changing patterns in opioid use among residents with cancer, including relatively abrupt 10% and 21% decreases in use of fentanyl patches and other strong opioids, respectively, after the 2006 implementation of Medicare Part D. In the years since Medicare Part D was introduced, some treatment practices in nursing homes have not been concordant with clinical guidelines for pain management among older adults. Among a contemporary population of long-stay nursing home residents with and without cancer, 10.0% (95% CI: 9.4–10.6%) of those who began receiving a long-acting opioid after nursing home admission had not previously received opioid therapy. Odds of naïve initiation of these potent opioids were increased among residents with terminal prognosis, functional impairment, feeding tubes, and cancer. This dissertation provides new evidence on pharmaceutical management of pain and on Medicare Part D’s impact on opioid use in nursing home residents. Results from this dissertation shed light on nursing home residents’ access to pain-related health care services and provide initial directions for targeted efforts to improve the quality of pain treatment in nursing homes.
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Gallo, Maria L. "Nursing advocacy and the accuracy of intravenous to oral opioid conversion at discharge in the cancer patient." [Tampa, Fla] : University of South Florida, 2009. http://purl.fcla.edu/usf/dc/et/SFE0003235.

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Books on the topic "Analgesics Administration"

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Reinhard, Sittl, and Budd Keith, eds. Practice of transdermal pain therapy. Bremen: Uni-Med, 2005.

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American Society of Health-System Pharmacists., ed. Demystifying opioid conversion calculations: A guide for effective dosing. Bethesda, MD: American Society of Health-System Pharmacists, 2010.

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Pasero, Chris. Pain assessment and pharmacologic management. St. Louis, Mo: Elsevier/Mosby, 2011.

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Margo, McCaffery, ed. Pain assessment and pharmacologic management. St. Louis, Mo: Mosby, 2011.

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Nebreda, Carlos L. Manual de fármacos utilizados en el tratamiento del dolor crónico. Seattle: IASP, 2000.

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Perras, Christine. A prospective randomized study to compare patient controlled analgesia, continuous intravenous infusion and intermittent intramuscular injection of morphine for acute, intractable post-operative pain. [Ottawa]: Ottawa Civic Hospital, 1989.

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Michael, Ferrante F., Ostheimer Gerard W, and Covino Benjamin G. 1930-, eds. Patient-controlled analgesia. Boston: Blackwell Scientific Publications, 1990.

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Patient-controlled analgesia. Boston: Blackwell Scientific Publications, 1990.

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Costantino, Benedetti, Chapman C. Richard, Giron G. P. 1934-, Bonica John J. 1917-, International Association for the Study of Pain., and World Congress on Pain (5th : 1987 : Hamburg, Germany), eds. Opioid analgesia: Recent advances in systemic administration. New York: Raven Press, 1990.

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Dumais, Lisa Jane. Factors influencing nurses' decisions regarding dosage of analgesics administered to post-operative patients. 1992.

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Book chapters on the topic "Analgesics Administration"

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Fairbanks, Carolyn A., and Cristina D. Peterson. "Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary." In Neurobiological Studies of Addiction in Chronic Pain States, 81–107. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1856-0_6.

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Penn, Richard D. "Peptides for Analgesia: Intrathecal Administration." In Advances in Pain Therapy I, 69–77. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77555-0_8.

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Chohan, Amandeep S., and Elizabeth B. Davidow. "Clinical Pharmacology and Administration of Fluid, Electrolyte, and Blood Component Solutions." In Veterinary Anesthesia and Analgesia, 386–413. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119421375.ch21.

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Wade, Carrie L., and Carolyn A. Fairbanks. "The Self-administration of Analgesic Drugs in Experimentally Induced Chronic Pain." In Behavioral Neurobiology of Chronic Pain, 217–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/7854_2014_344.

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White, P. F. "Patient-Controlled Analgesia II: Comparative Studies and Alternative Routes of Administration." In Anesthesiology and Pain Management, 245–48. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3318-0_20.

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Ewan, Eric E., and Thomas J. Martin. "Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction?" In Neurobiological Studies of Addiction in Chronic Pain States, 17–30. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1856-0_2.

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Kopf, Andreas, Steffen Schmidt, and Christoph Stein. "Topical administration of analgesics." In Textbook of Palliative Medicine, 450–57. CRC Press, 2009. http://dx.doi.org/10.1201/b13272-59.

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Brock, Cara, and Patti Murray. "Rectal Administration of Analgesics." In Pain, 225–32. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780197542873.003.0027.

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When the oral route is no longer viable, and intravenous or subcutaneous routes are undesirable, the rectal administration of opioids and other analgesics is a viable option for pain management. Rectal anatomy and blood flow allow for the absorption and distribution of opioids via this route. Although the rectum has a smaller surface area, higher pH, and decreased fluid content compared to the upper gastrointestinal tract, rectally administered opioids are absorbed in a similar manner by passive diffusion. Opioids in the form of suppositories, tablets, and oral solutions may all be administered via a stoma or the rectum as an alternate route.
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Zempsky, William T. "Topical anaesthetics and analgesics." In Oxford Textbook of Paediatric Pain, 486–94. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642656.003.0047.

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Topical administration of anaesthetics and analgesics can allow for the efficient, painless delivery of medications which may reduce systemic side effects associated with the medication while providing clinical advantages over injected or oral administration for the same clinical situation. Topical anaesthetics have become widely used prior to a variety of painful procedures in children including venous access, laceration repair, and injections. Topical administration of non-steroidal anti-inflammatory drugs, lidocaine, capsaicin, and other agents also are useful for a range of conditions including acute and chronic musculoskeletal pain, and neuropathic pain.
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Zempsky, William T. "Topical anesthetics and analgesics." In Oxford Textbook of Pediatric Pain, edited by Bonnie J. Stevens, Gareth Hathway, and William T. Zempsky, 494–500. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198818762.003.0047.

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Topical administration of anesthetics and analgesics can allow for the efficient, painless delivery of medications that may reduce systemic side effects associated with the medication, whilst providing clinical advantages over injected or oral administration for the same clinical situation. Topical anesthetics have become widely used prior to a variety of painful procedures in children, including venous access, laceration repair, and injections. Topical administration of nonsteroidal anti-inflammatory drugs, lidocaine, capsaicin, and other agents also are useful for a range of conditions, including acute and chronic musculoskeletal pain, and neuropathic pain.
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Conference papers on the topic "Analgesics Administration"

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Hunt, Clive, Paul Turner, and Amy Pharaoh. "101 Timely administration of analgesia." In The APM’s Annual Supportive and Palliative Care Conference, In association with the Palliative Care Congress, “Towards evidence based compassionate care”, Bournemouth International Centre, 15–16 March 2018. British Medical Journal Publishing Group, 2018. http://dx.doi.org/10.1136/bmjspcare-2018-aspabstracts.128.

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Latifi, A., C. Kapp, A. DeMaio, J. Thiboutot, H. J. Lee, L. B. Yarmus, E. B. Or, A. Hillel, and D. J. Feller-Kopman. "Analgesic Medication Administration in COVID-19 Positive ARDS Patients Undergoing Tracheostomy." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2518.

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De jonckheere, J., M. Jeanne, A. Keribedj, M. Delecroix, and R. Logier. "Closed-loop administration of analgesic drugs based on heart rate variability analysis*." In 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2018. http://dx.doi.org/10.1109/embc.2018.8512330.

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Nunes, C. S., M. Mahfouf, D. A. Linkens, and J. Peacock. "Multivariable fuzzy control for the simultaneous administration of the anaesthetic and the analgesic drugs." In 2003 European Control Conference (ECC). IEEE, 2003. http://dx.doi.org/10.23919/ecc.2003.7085097.

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Yang, Qiong-Fang, Li-Zu Xiao, Wei-Jiao Xie, and Yun-Hai Qiu. "Analgesic Contrast of Diverse Administrations of Botulinum Neurotoxin A (BoTN/A) Using Rat Neuropathic Pain Model." In The International Conference on Biological Sciences and Technology. Paris, France: Atlantis Press, 2016. http://dx.doi.org/10.2991/bst-16.2016.38.

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Reports on the topic "Analgesics Administration"

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Acred, Aleksander, Milena Devineni, and Lindsey Blake. Opioid Free Anesthesia to Prevent Post Operative Nausea/Vomiting. University of Tennessee Health Science Center, July 2021. http://dx.doi.org/10.21007/con.dnp.2021.0006.

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Purpose The purpose of this study is to compare the incidence of post-operative nausea and vomiting (PONV) in opioid-utilizing and opioid-free general anesthesia. Background PONV is an extremely common, potentially dangerous side effect of general anesthesia. PONV is caused by a collection of anesthetic and surgical interventions. Current practice to prevent PONV is to use 1-2 antiemetics during surgery, identify high risk patients and utilize tracheal intubation over laryngeal airways when indicated. Current research suggests minimizing the use of volatile anesthetics and opioids can reduce the incidence of PONV, but this does not reflect current practice. Methods In this scoping review, the MeSH search terms used to collect data were “anesthesia”, “postoperative nausea and vomiting”, “morbidity”, “retrospective studies”, “anesthesia, general”, “analgesics, opioid”, “pain postoperative”, “pain management” and “anesthesia, intravenous”. The Discovery Search engine, AccessMedicine and UpToDate were the search engines used to research this data. Filters were applied to these searches to ensure all the literature was peer-reviewed, full-text and preferably from academic journals. Results Opioid free anesthesia was found to decrease PONV by 69%. PONV incidence was overwhelming decreased with opioid free anesthesia in every study that was reviewed. Implications The future direction of opioid-free anesthesia and PONV prevention are broad topics to discuss, due to the nature of anesthesia. Administration of TIVA, esmolol and ketamine, as well as the decision to withhold opioids, are solely up to the anesthesia provider’s discretion. Increasing research and education in the importance of opioid-free anesthesia to decrease the incidence of PONV will be necessary to ensure anesthesia providers choose this protocol in their practice.
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Lumpkin, Shamsie, Isaac Parrish, Austin Terrell, and Dwayne Accardo. Pain Control: Opioid vs. Nonopioid Analgesia During the Immediate Postoperative Period. University of Tennessee Health Science Center, July 2021. http://dx.doi.org/10.21007/con.dnp.2021.0008.

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Background Opioid analgesia has become the mainstay for acute pain management in the postoperative setting. However, the use of opioid medications comes with significant risks and side effects. Due to increasing numbers of prescriptions to those with chronic pain, opioid medications have become more expensive while becoming less effective due to the buildup of patient tolerance. The idea of opioid-free analgesic techniques has rarely been breached in many hospitals. Emerging research has shown that opioid-sparing approaches have resulted in lower reported pain scores across the board, as well as significant cost reductions to hospitals and insurance agencies. In addition to providing adequate pain relief, the predicted cost burden of an opioid-free or opioid-sparing approach is significantly less than traditional methods. Methods The following groups were considered in our inclusion criteria: those who speak the English language, all races and ethnicities, male or female, home medications, those who are at least 18 years of age and able to provide written informed consent, those undergoing inpatient or same-day surgical procedures. In addition, our scoping review includes the following exclusion criteria: those who are non-English speaking, those who are less than 18 years of age, those who are not undergoing surgical procedures while admitted, those who are unable to provide numeric pain score due to clinical status, those who are unable to provide written informed consent, and those who decline participation in the study. Data was extracted by one reviewer and verified by the remaining two group members. Extraction was divided as equally as possible among the 11 listed references. Discrepancies in data extraction were discussed between the article reviewer, project editor, and group leader. Results We identified nine primary sources addressing the use of ketamine as an alternative to opioid analgesia and post-operative pain control. Our findings indicate a positive correlation between perioperative ketamine administration and postoperative pain control. While this information provides insight on opioid-free analgesia, it also revealed the limited amount of research conducted in this area of practice. The strategies for several of the clinical trials limited ketamine administration to a small niche of patients. The included studies provided evidence for lower pain scores, reductions in opioid consumption, and better patient outcomes. Implications for Nursing Practice Based on the results of the studies’ randomized controlled trials and meta-analyses, the effects of ketamine are shown as an adequate analgesic alternative to opioids postoperatively. The cited resources showed that ketamine can be used as a sole agent, or combined effectively with reduced doses of opioids for multimodal therapy. There were noted limitations in some of the research articles. Not all of the cited studies were able to include definitive evidence of proper blinding techniques or randomization methods. Small sample sizes and the inclusion of specific patient populations identified within several of the studies can skew data in one direction or another; therefore, significant clinical results cannot be generalized to patient populations across the board.
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Canellas, Joao Vitor, Fabio Ritto, and Paul Tiwana. Comparative efficacy and safety of pharmacological interventions to reduce inflammatory complications after mandibular third molar surgery: a systematic review and network meta-analysis protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2021. http://dx.doi.org/10.37766/inplasy2021.7.0069.

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Review question / Objective: This systematic review aims to compare the effects of different drugs to reduce postoperative inflammatory complications (pain, edema, and trismus) after mandibular third molar surgery by applying a frequentist network meta-analysis approach. To this end, the proposed study will answer the following questions: 1) Among diverse drugs currently available, which postoperative pharmacological regimen is the most efficient to reduce pain after mandibular third molar surgery? 2) Is the pre-emptive analgesia effective in reducing pain immediately after the mandibular third molar surgery? In this case, 3) Which preoperative pharmacological regimen is the most efficient? 4) Among diverse corticosteroids currently available, what is the best option to control the edema induced by the surgery? 5) What is the optimal dose and route of administration of corticosteroids prior to mandibular third molar surgery to control the pain/ edema induced by the surgery? Condition being studied: Inflammatory complications after mandibular third molar surgery (Pain, edema, and trismus).
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Harris, Gregory, Brooke Hatchell, Davelin Woodard, and Dwayne Accardo. Intraoperative Dexmedetomidine for Reduction of Postoperative Delirium in the Elderly: A Scoping Review. University of Tennessee Health Science Center, July 2021. http://dx.doi.org/10.21007/con.dnp.2021.0010.

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Background/Purpose: Post-operative delirium leads to significant morbidity in elderly patients, yet there is no regimen to prevent POD. Opioid use in the elderly surgical population is of the most significant risk factors for developing POD. The purpose of this scoping review is to recognize that Dexmedetomidine mitigates cognitive dysfunction secondary to acute pain and the use of narcotic analgesia by decreasing the amount of norepinephrine (an excitatory neurotransmitter) released during times of stress. This mechanism of action also provides analgesia through decreased perception and modulation of pain. Methods: The authors developed eligibility criteria for inclusion of articles and performed a systematic search of several databases. Each of the authors initially selected five articles for inclusion in the scoping review. We created annotated literature tables for easy screening by co-authors. After reviewing the annotated literature table four articles were excluded, leaving 11 articles for inclusion in the scoping review. There were six level I meta-analysis/systematic reviews, four level II randomized clinical trials, and one level IV qualitative research article. Next, we created a data-charting form on Microsoft Word for extraction of data items and synthesis of results. Results: Two of the studies found no significant difference in POD between dexmedetomidine groups and control groups. The nine remaining studies noted decreases in the rate, duration, and risk of POD in the groups receiving dexmedetomidine either intraoperatively or postoperatively. Multiple studies found secondary benefits in addition to decreased POD, such as a reduction of tachycardia, hypertension, stroke, hypoxemia, and narcotic use. One study, however, found that the incidence of hypotension and bradycardia were increased among the elderly population. Implications for Nursing Practice: Surgery is a tremendous stressor in any age group, but especially the elderly population. It has been shown postoperative delirium occurs in 17-61% of major surgery procedures with 30-40% of the cases assumed to be preventable. Opioid administration in the elderly surgical population is one of the most significant risk factors for developing POD. With anesthesia practice already leaning towards opioid-free and opioid-limited anesthetic, the incorporation of dexmedetomidine could prove to be a valuable resource in both reducing opioid use and POD in the elderly surgical population. Although more research is needed, the current evidence is promising.
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