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1

Dowie, Robin. Anaesthetics. London: HMSO Books, 1991.

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2

Peter, Conzen, ed. Toxicity of anaesthetics. London: Baillière Tindall, 2003.

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3

Lunn, John N. Lecture notes on anaesthetics. 4th ed. Oxford: Blackwell Scientific, 1991.

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4

Miller, Pierre A. Neurotoxicity of local anaesthetics. [Toronto: University of Toronto, Faculty of Dentistry], 1999.

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5

The anaesthetics of architecture. Cambridge, Mass: MIT Press, 1999.

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6

Smith, J. Dental general anaesthetics discussion paper. Barking: Directorate of Public Health Medicine, Barking & Havering Health Authority, 1996.

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7

1828-1896, Richardson Benjamin Ward, ed. On chloroform and other anaesthetics. Place of publication not identified]: [publisher not identified], 1990.

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8

Ponte, Jose. A new short textbook of anaesthetics, intensive care and pain relief. London: Hodder and Stoughton, 1986.

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9

Anaesthesia and anaesthetics, general and local. Memphis, USA: General Books, 2012.

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10

Metcalfe, Stuart A. An introduction to local anaesthetics for podiatrists. Market Bosworth: SAM Healthcare, 1994.

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11

Ostlere, Gordon. Ostlere & Bryce-Smith's anaesthetics for medical students. Edinburgh: Churchill Livingstone, 1989.

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12

Ostlere, Gordon. Ostlere & Bryce-Smith's anaesthetics for medical students. Edinburgh: Churchill Livingstone, 1989.

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13

Gareth, Jones J., and Hanning Christopher D, eds. The Upper airway. London: Baillière Tindall, 1995.

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14

Griselda, Cooper, ed. Guidelines in clinical anaesthesia. Oxford: Blackwell Scientific Publications, 1985.

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15

Griselda, Cooper, ed. Guidelines in clinical anaesthesia. Oxford: Blackwell Scientific, 1985.

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16

Norris, Walter. Norris and Campbell's Anaesthetics, resuscitation, and intensive care. 6th ed. Edinburgh: Churchill Livingstone, 1985.

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17

Kibble, Anne Victoria. The effects of intravenous anaesthetics on seizure activity. Manchester: University of Manchester, 1995.

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18

Donald, Campbell. Norris and Campbell's anaesthetics, resuscitation, and intensive care. 8th ed. New York: Churchill Livingstone, 1997.

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19

Norris, Walter. Norris and Campbell's anaesthetics, resuscitation and intensive care. 6th ed. Edinburgh: Churchill Livingstone, 1985.

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20

Norris, Walter. Norris and Campbell's anaesthetics, resuscitation, and intensive care. 7th ed. Edinburgh: Churchill Livingstone, 1990.

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21

W, Dundee John, and Sear J. W, eds. Intravenous anaesthesia: What is new? London: Bailière Tindall, 1991.

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22

Snow, Stephanie J. Blessed days of anaesthesia: How anaesthetics changed the world. Oxford: Oxford University Press, 2009.

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23

Madsen, Jörn Bo, and Georg Emil Cold. The Effects of Anaesthetics upon Cerebral Circulation and Metabolism. Vienna: Springer Vienna, 1990. http://dx.doi.org/10.1007/978-3-7091-3680-5.

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24

Williams, Winston W. The effect of anaesthetics and pressure on membrane systems. Salford: University of Salford, 1989.

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25

Cunningham, Bonnie Wilde. Bearing the pain: Anaesthetics of impersonality in modernist fiction. Ann Arbor, Mich: UMI, 1994.

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26

Carpenter, Mark L. The interaction of pressure and anaesthetics with lipid bilayers. Salford: University of Salford, 1987.

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27

Snow, Stephanie J. Blessed days of anaesthesia: How anaesthetics changed the world. Oxford: Oxford University Press, 2009.

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28

Young, T. M. A short history of the Section of Anaesthetics of the Royal Society of Medicine and the Society of Anaesthetists. [London]: Royal Society of Medicine, 1998.

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29

Atkinson, R. S. A Synopsis of anaesthesia. Bristol: Wright, 1987.

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30

S, Atkinson R., Rushman G. B, and Lee Alfred J, eds. A synopsis of anaesthesia. Bristol: Wright, 1987.

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31

Dripps, Robert Dunning. Introduction to anesthesia: The principles of safe practice. 7th ed. London: Saunders, 1988.

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32

E, Heavner James, ed. Technical manual of anesthesiology: An introduction. New York: Raven Press, 1989.

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33

K, Sykes M., ed. A history of the Nuffield Department of Anaesthetics, Oxford, 1937-1987. Oxford: Oxford University Press, 1987.

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34

D, Campbell. Norris and Campbell's nurse's guide to anaesthetics, resuscitation and intensive care. 7th ed. Edinburgh: Churchill Livingstone, 1987.

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35

Kulkarni, Kunal, James Harrison, Mohamed Baguneid, and Bernard Prendergast, eds. Anaesthetics. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198729426.003.0020.

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Current anaesthetic practice is provided using a combination of many different available techniques and drugs, with the primary aim of ensuring patient safety and high-quality care are provided for patients. Anaesthesia today is extremely safe, with mortality less than one death in 250 000 directly related to anaesthetic intervention alone. This is due to a continued focus on the principles of patient safety and quality of care, underpinned by continued innovation in pharmacology, applied physiology, physics, and engineering. These have yielded improved techniques and technologies to enhance airway management, provide ventilatory assistance and haemodynamic support, and monitor physiological parameters. Modern professional practice is continually seeking to improve by emphasizing the importance of individual non-technical skills in educational curricula and the workplace. In addition, anaesthetists are heavily involved in the integration of human factors science into health-care organizations.
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36

Brundle, Joanna. Anaesthetics. BookLife Publishing Ltd., 2019.

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37

Hendrickx, Jan F. A., André van Zundert, and Andre De Wolf. Inhaled anaesthetics. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0014.

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Inhaled anaesthetic drugs are administered via the lungs to provide ‘general anaesthesia’. They are considered complete anaesthetics because they in and by themselves can in most patients ensure all clinical end-points that are required for ‘general anaesthesia’ (unconsciousness, immobility, and haemodynamic stability). The dose–response curve of each clinical end-point is conveniently defined by its mid-point, the end-expired concentration Fa that ensures response suppression in 50 % of the patients (MACawake, MAC, and MACBAR). By understanding the dose–response curves and the factors that influence them (pharmacodynamics), the target Fa and the dose of other drugs can be selected in each individual patient. This target Fa is achieved by adjusting the carrier fresh gas flow (O2, air, N2O) and agent vaporizer setting Fd. ‘Pharmacokinetics’ is the study of the factors that affect the partial pressure cascade from the vaporizer down to the site of action. Because IADs are transported down a partial pressure gradient, Fa will always try to approach the inspired concentration Fi, a process that is described by the Fa/Fi ratio over time. Both Fa and Fi are routinely measured. N2O remains widely used, with scientific scrutiny rather than belief finally delineating its advantages and disadvantages. Xenon, the near-ideal agent, is discussed briefly because it may enter clinical practice despite its cost because of its potential advantages in a yet to be defined subgroup of high-risk patients. The carrier gas N2 is often overlooked, but deserves careful analysis to help the reader understand how rebreathing affects its kinetics in a circle breathing system.
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38

Absalom, Anthony, and John Sear. Intravenous anaesthetics. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0015.

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In recent decades, increasing attention has been focused on the intravenous anaesthetic agents. This interest has been stimulated by the discovery and availability of agents with increasingly favourable pharmacokinetic and dynamic properties, coupled with advances in knowledge of pharmacology and advances in computer technology. For most patients and operative procedures, anaesthesia is induced with a bolus or fast infusion of a short-acting drug, most commonly propofol. Increasingly, anaesthesia is thereafter also maintained with an infusion of an agent with favourable kinetics, again usually of propofol, commonly supplemented with boluses or infusions of opioids. Propofol is also commonly used for procedural and intensive care sedation. It has highly favourable pharmacokinetics and pharmacodynamics for these applications as sedative or hypnotic agent—rapid, smooth onset, minimal accumulation, and rapid smooth offset of effect—but is by no means an ideal agent. In some specific situations, such as when its haemodynamic or respiratory effects are detrimental, use of alternative agents such as ketamine and etomidate are warranted. All the currently available agents have adverse effects, some of which are related to the active compound and some of which are related to the vehicle. Efforts are thus being made to develop new formulations, with fewer adverse effects, and to develop newer and better drugs. In the future we are also likely to see increasing use of older agents, but for newer indications (such as the use of ketamine as an antidepressant).
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39

Padley, Anthony. Westmead Anaesthetics. McGraw-Hill Medical Publishing Division, 2009.

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40

Practical Anaesthetics. Nabu Press, 2010.

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41

Heyes, Cressida J. Anaesthetics of Existence. Duke University Press, 2020. http://dx.doi.org/10.1215/9781478009320.

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42

F, Litch W. Anaesthesia and Anaesthetics. Creative Media Partners, LLC, 2018.

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43

Banerjee, Ashis, and Clara Oliver. Anaesthetics and pain management. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198786870.003.0003.

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Emergency medicine trainees are required to complete an anaesthetic placement and obtain basic anaesthetic competencies. This chapter is not intended to provide the practical skills for delivering an anaesthetic. Instead, this chapter focuses on the theory of managing and predicting a difficult airway in the emergency department, which is more likely to appear in the short-answer (SAQ) paper. It also focuses on procedural sedation which also may appear in the SAQ paper due to its growing use in the emergency department (ED). This chapter also covers pain management, for which the Royal College of Emergency Medicine (RCEM) have introduced clinical standards. In addition, this chapter covers the use of peripheral nerve blocks such as a fascia iliaca block for neck of femur fractures. Due to the growing use of peripheral nerve blocks in the ED, such detailed knowledge is required.
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44

Stacey, Victoria. Anaesthetics and pain management. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199592777.003.0003.

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Emergency airway care - Identifying the difficult airway - Emergency airway drugs - Rapid sequence induction (RSI) - Procedural sedation - Pain management - Local anaesthesia - Nerve blocks - Intravenous regional anaesthesia (Bier’s block) - SAQ
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45

Lecture Notes on Anaesthetics. Blackwell Science Ltd, 1986.

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46

Lunn, John N., and J. N. Lunn. Lecture Notes on Anaesthetics. Blackwell Science, 1991.

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47

Lawin, P. Intravenous Anaesthetics: Third European Symposium on Modern Anaesthetic Agents (Anaesthesiologie Und Intensivmedizin). Springer-Verlag, 1991.

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48

Wilmot, Buxton Dudley. Anaesthetics: Their Uses and Administration. Creative Media Partners, LLC, 2018.

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49

Wilmot, Buxton Dudley. Anaesthetics: Their Uses and Administration. Franklin Classics Trade Press, 2018.

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50

Wilmot, Buxton Dudley. Anaesthetics: Their Uses and Administration. Franklin Classics Trade Press, 2018.

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