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Published: 10 December 2022
Last updated: 29 January 2023

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1

1921-, Tsubaki Tadao, and Yase Yoshirō, eds. Amyotrophic lateral sclerosis: Recent advances in research and treatment : proceedings of the International Conference on Amyotrophic Lateral Sclerosis, Kyoto, Japan, 29-31, October 1987. Amsterdam: Excerpta Medica, 1988.

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2

Excellence, National Institute for Clinical. Guidance on the use of Riluzole (Rilutek) for the treatment of Motor Neurone Disease. London: National Institute for Clinical Excellence, 2001.

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3

Lou Gehrig Disease, ALS or Amyotrophic Lateral Sclerosis explained: ALS symptoms, signs, stages, types, diagnosis, treatment, caregiver tips, aids and what to expect is all covered. [Ireland]: IMB Publishing, 2013.

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4

Richer, Catherine Balsdon. Occupational therapy practice guidelines for adults with neurodegenerative diseases: Multiple sclerosis, transverse myelitis, and amyotrophic lateral sclerosis. Bethesda, Md: American Occupational Therapy Association, 1999.

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5

United States. Congress. House. A bill to amend the Social Security Act to waive the 24-month waiting period for Medicare coverage of individuals disabled with amyotrophic lateral sclerosis (ALS), and to provide Medicare coverage of drugs used for treatment of ALS. Washington, D.C: U.S. G.P.O., 1999.

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6

United States. Congress. Senate. A bill to amend the Social Security Act to waive the 24-month waiting period for Medicare coverage of individuals disabled with amyotrophic lateral sclerosis (ALS), and to provide Medicare coverage of drugs and biologicals used for the treatment of ALS or for the alleviation of symptoms relating to ALS. Washington, D.C: U.S. G.P.O., 1999.

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7

United, States Congress Senate Committee on Appropriations Subcommittee on Departments of Labor Health and Human Services Education and Related Agencies. Amyotrophic lateral sclerosis (ALS): Hearing before a subcommittee of the Committee on Appropriations, United States Senate, One Hundred Ninth Congress, first session, special hearing, May 11, 2005, Washington, DC. Washington: U.S. G.P.O., 2006.

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8

Williams, Brian J. (Brian Jeremy), 1976- and American Academy of Orthopaedic Surgeons, eds. Principles of ALS care. Sudbury, Mass: Jones and Bartlett Publishers, 2011.

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9

Gulf War exposures: Hearing before the Subcommittee on Health of the Committee on Veterans' Affairs, U.S. House of Representatives, One Hundred Tenth Congress, first session, July 26, 2007. Washington: U.S. G.P.O., 2008.

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10

Brain disorders sourcebook: Basic consumer health information about acquired and traumatic brain injuries, brain tumors, cerebral palsy and other genetic and congenital brain disorders, infections of the brain, epilepsy, and degenerative neurological disorders such as dementia, huntington disease, and amyotrophic lateral sclerosis (ALS) : along with information on brain structure and function, treatment and rehabilitation options, a glossary of terms related to brain disorders, and a directory of resources for more information. 3rd ed. Detroit, MI: Omnigraphics, 2010.

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11

Shannon, Joyce Brennfleck. Brain disorders sourcebook: Basic consumer health information about acquired and traumatic brain injuries, brain tumors, cerebral palsy and other genetic and congenital brain disorders, infections of the brain, epilepsy, and degenerative neurological disorders such as dementia, huntington disease, and amyotrophic lateral sclerosis (ALS) : along with information on brain structure and function, treatment and rehabilitation options, a glossary of terms related to brain disorders, and a directory of resources for more information. 3rd ed. Detroit, MI: Omnigraphics, 2010.

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12

Sørensen, Julie. Amyotrophic Lateral Sclerosis: From Diagnosis to Treatment. Nova Science Publishers, Incorporated, 2020.

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13

Amyotrophic Lateral Sclerosis: Symptoms, Treatment and Prognosis. Nova Science Pub Inc, 2012.

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14

Sørensen, Julie. Amyotrophic Lateral Sclerosis: From Diagnosis to Treatment. Nova Science Publishers, Incorporated, 2020.

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15

T, Caroscio James, ed. Amyotrophic lateral sclerosis: A guide to patient care. New York: Thieme, 1986.

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16

FRCGP, Oliver David, Borasio Gian Domenico, and Walsh Declan, eds. Palliative care in amyotrophic lateral sclerosis: From diagnosis to bereavement. 2nd ed. Oxford: Oxford University Press, 2006.

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17

(Editor), David Oliver, Gian Domenico Borasio (Editor), and Declan Walsh (Editor), eds. Palliative Care in Amyotrophic Lateral Sclerosis: From Diagnosis to Bereavement. Oxford University Press, USA, 2006.

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18

Johnston, Wendy, David Oliver, and Gian Domenico Borasio. Palliative Care in Amyotrophic Lateral Sclerosis: From Diagnosis to Bereavement. Oxford University Press, 2014.

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19

Johnston, Wendy, David Oliver, and Gian Domenico Borasio. Palliative Care in Amyotrophic Lateral Sclerosis: From Diagnosis to Bereavement. Oxford University Press, Incorporated, 2014.

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20

David, Oliver, Borasio Gian Domenico, and Walsh Declan, eds. Palliative care in amyotrophic lateral sclerosis (motor neurone disease). Oxford: Oxford University Press, 2000.

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21

(Editor), David Oliver, Gian Domenico Borasio (Editor), and Declan Walsh (Editor), eds. Palliative Care in Amyotrophic Lateral Sclerosis (Motor Neuron Disease). Oxford University Press, USA, 2000.

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22

China) International Conference on Advances in Structural Dynamics (2000 : Hong Kong and Tadao Tsubaki. Amyotrophic Lateral Sclerosis: Recent Advances in Research and Treatment : Proceedings of the International Conference on Amyotrophic Lateral Sclero (International Congress Series). Excerpta Medica, 1988.

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23

Riluzole for the treatment of amyotrophic lateral sclerosis: An assessment of clinical efficacy and safety. Ottawa: Canadian Coordinating Office for Health Technology Assessment, 2003.

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24

The use of riluzole in the treatment of amyotrophic lateral sclerosis (motor neurone disease). Sheffield: Trent Institute for Health Services Research, 1997.

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25

Oliver, David. Palliative Care in Ameyotrophic Lateral Scloerosis. 2nd ed. Oxford University Press, 2007.

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26

Watermeyer, Tamlyn J., and Laura H. Goldstein. Psychological research in amyotrophic lateral sclerosis: Past, present, and future. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757726.003.0001.

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This chapter, of particular interest to those interested in psychological treatments for people with amyotrophic lateral sclerosis (ALS), outlines earlier work that sought to identify correlates of reduced well-being and quality of life in people with ALS and delineates possible targets for intervention. In this context, the chapter then evaluates several studies that have investigated psychological interventions for optimizing well-being in people with ALS and their caregivers. The chapter reviews current efforts to address the paucity of interventional research in this patient group, focusing on five therapies that have so far been evaluated for treatment efficacy. These therapies include hypnosis, mindfulness, cognitive behavioural therapy, expressive disclosure therapy, and dignity therapy. The main findings from these studies and their clinical implications for people with ALS and their families are discussed. Recommendations for future research are considered, together with a discussion of the implementation of such interventions in therapeutic or multidisciplinary settings.
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27

1936-, Miyaoka Osahito, Sakiyama Osamu 1937-, and Krauss Michael E. 1934-, eds. The vanishing languages of the Pacific rim. Oxford: Oxford University Press, 2007.

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28

(Editor), Osahito Miyaoka, Osamu Sakiyama (Editor), and Michael E. Krauss (Editor), eds. The Vanishing Languages of the Pacific Rim. Oxford University Press, USA, 2007.

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29

Als Skills Review. Jones & Bartlett Publishers, 2008.

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30

Amyotrophic Lateral Sclerosis (ALS): Hearing Before a Subcommittee of the Committee on Appropriations, United States Senate, One Hundred Ninth Congres. Not Avail, 2006.

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31

Brock, Nicholle, and American Academy American Academy of Orthopaedic Surgeons (AAOS). Principles of ALS Care. Jones & Bartlett Learning, LLC, 2010.

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32

Stafstrom, Carl E. Dietary Therapy for Neurological Disorders. Edited by Jong M. Rho. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0018.

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Dietary and metabolic therapies such as the high-fat, low-carbohydrate ketogenic diet (KD) are best known for the treatment of intractable epilepsy. Yet, dietary and metabolic approaches have also found some efficacy in a wide variety of other neurological diseases, including autism spectrum disorder, brain trauma, Alzheimer’s disease, sleep disorders, brain tumors, pain, and multiple sclerosis, as discussed in other chapters of this volume. This chapter provides an overview of clinical and experimental studies using the KD in an array of other neurologic disorders: amyotrophic lateral sclerosis, Parkinson’s disease, mood disorders, and migraine. Despite the wide spectrum of pathophysiological mechanisms underlying these disorders, it is possible that one or more final common metabolic pathways might be influenced by dietary intervention. There is compelling albeit preliminary evidence that correction of aberrant energy metabolism through dietary manipulation could favorably influence diverse neurological diseases.
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33

Macauley, Robert C. Neuropalliative Care (DRAFT). Edited by Robert C. Macauley. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199313945.003.0015.

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Neuropalliative care encompasses disorders of consciousness, cognitive impairment, trauma, and other conditions. Each prompts specific ethical considerations, such as the often shifting values (and even personalities) of patients with dementia, forcing one to determine whether previously expressed wishes are determinative. Patients with amyotrophic lateral sclerosis maintain cognition long after motor failure, and the predicable trajectory makes possible specific advance care planning. Patients who have suffered acute spinal cord injury may initially demand withdrawal of life sustaining medical treatment, yet studies have shown a significant proportion eventually achieve a quality of life acceptable to them. And patients who have suffered a stroke often recover significant function, thus making early limitation of treatment a potential “self-fulfilling prophecy.”
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34

Brain disorders sourcebook: Basic consumer health information about strokes, epilepsy, amyotrophic lateral sclerosis (ALS/Lou Gehrig's disease) Parkinson's disease, brain tumors, cerebral palsy, headache, Tourette syndrome, and more ; along with statistical data, treatment and rehabilitation options, coping strategies, reports on current initiatives, a glossary, and resource listings for additional help and information. Detroit, MI: Omnigraphics, 1999.

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35

Mastroeni, Diego F. An Epigenetics Perspective on Diseases of the Central Nervous System. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0011.

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In the next two decades epigenetics could revolutionize understanding and treatment of diseases of the central nervous system. New research already demonstrates that manipulation of epigenetic mechanisms in vivo and in vitro can ameliorate a host of pathogenic processes associated with neurodegenerative disorders such as Alzheimer’s disease (AD), Parkinson’s (PD), amyotrophic lateral sclerosis (ALS), Huntington’s (HD), and multiple sclerosis (MS), among others. These advances have come relatively rapidly for a field that is still in its infancy compared to the much longer history of epigenetics in developmental biology. Epigenetic modifications are all-encompassing, from nucleotides to amino acids. They are capable of altering transcriptional to biochemical activity in a consistent manner across thousands of genes and hundreds of biologic pathways, yet they can do so differentially even in individuals or cells with identical gene codes. As such, epigenetic modifications are likely to touch on virtually all the mechanisms described in this book.
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36

Sajgalikova, Katerina, Erik K. St Louis, and Peter Gay. Neuromuscular disorders and sleep. Edited by Sudhansu Chokroverty, Luigi Ferini-Strambi, and Christopher Kennard. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199682003.003.0030.

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This chapter examines the range of sleep disturbances seen in patients with neuromuscular disorders, particularly emphasizing sleep-related breathing disorders which may be a presenting manifestation of neuromuscular disorders, and which significantly contribute to morbidity and mortality in this patient population. It provides an overview of physiological and pathological alterations in neuromuscular breathing mechanisms and control during sleep. The symptoms and forms of sleep disordered breathing (SDB) seen in specific neuromuscular disorders such as amyotrophic lateral sclerosis, myopathies, and disorders of neuromuscular junction transmission are reviewed. The chapter concludes with a discussion of management strategies for neuromuscular disorder patients with SDB, which is common in such patients, requiring generalists, neurologists, and sleep physicians to work together toward prompt diagnosis and optimal treatment approaches.
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37

Cohen, Jeffrey A., Justin J. Mowchun, Victoria H. Lawson, and Nathaniel M. Robbins. A 50-Year-Old Male with Speech, Swallowing, and Behavioral Difficulties. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190491901.003.0003.

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Treatment issues are discussed in the setting of a very challenging patient with amyotrophic lateral sclerosis with frontotemporal dementia (FTD), including management of neurological symptoms and cognitive dysfunction. Features of FTD are discussed. It is now appreciated that FTD is more common than previously thought. FTD can occur before the onset of motor symptoms. An ALS multidisciplinary clinic is the best approach for the care of ALS patients. Ethical issues are analyzed in this case as well. The need for the discussion of end of life issues is important for the patient family and caregivers. The careful consideration of tracheostomy and ventilator use is important in light of pulmonary function. Pulmonary function testing and sleep studies are helpful in managing respiratory issues. Palliative care consultation can be very beneficial.
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38

J, Judd Sandra, ed. Brain disorders sourcebook: Basic consumer health information about acquired and traumatic brain injuries, infections of the brain, epilepsy and seizure disorders, cerebral palsy, and degenerative neurological disorders, including amyotrophic lateral sclerosis (ALS), dementias, multiple sclerosis, and more; along with information on the brain's structure and function, treatment and rehabilitation options, reports on current research initiatives, a glossary of terms related to brain disorders and injuries, and a directory of sources for further help and information. 2nd ed. Detroit, MI: Omnigraphics, 2005.

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39

Ryskamp, Daniel A., Elena Popugaeva, and Ilya Bezprozvanny. Calcium Hypothesis of Neurodegeneration. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0003.

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Aged-related changes in neuronal physiology and stressors related to specific neurodegenerative diseases collude to undermine neuronal calcium homeostasis, which is a common pathological feature in the initiation and progression of Alzheimer’s disease(AD), Huntington’s disease (HD), Parkinson’s disease, amyotrophic lateral sclerosis, spinocerebellar ataxias, glaucoma, and several other neurodegenerative disorders. Mechanisms of calcium mishandling in these diseases are discussed in this chapter by focusing on HD as an example of a monogenic disease and AD as a multifactorial disease. As aberrant Ca2+ signals are particularly toxic to synaptic elements, this chapter further focuses on issues relevant to development of therapeutics that maintain neuronal circuitry and function through the stabilization of Ca2+ regulation. Ultimately, therapies that promote calcium homeostasis will likely be most effective when used in combination with disease-specific treatment strategies such as elimination of toxic Aβ‎ in AD or polyglutamine expanded Huntingtin protein in HD.
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