Academic literature on the topic 'Amyotrophic lateral sclerosis, ALS'
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Journal articles on the topic "Amyotrophic lateral sclerosis, ALS"
Brauer, Sandra. "Amyotrophic lateral sclerosis (ALS)." Journal of Physiotherapy 59, no. 1 (March 2013): 61. http://dx.doi.org/10.1016/s1836-9553(13)70155-3.
Full textCividini, Camilla, Silvia Basaia, Edoardo G. Spinelli, Elisa Canu, Veronica Castelnovo, Nilo Riva, Giordano Cecchetti, et al. "Amyotrophic Lateral Sclerosis–Frontotemporal Dementia." Neurology 98, no. 4 (December 1, 2021): e402-e415. http://dx.doi.org/10.1212/wnl.0000000000013123.
Full textKumar, Ravi. "Amyotrophic Lateral Sclerosis: Innovative Therapies for ALS under the Pipeline." Neurology & Neurotherapy Open Access Journal 7, no. 1 (2022): 1–9. http://dx.doi.org/10.23880/nnoaj-16000166.
Full textOrsini, Marco, Antônio Marcos da Silva Catharino, Valéria Camargo Silveira, Carlos Henrique Melo Reis, Marcos RG de Freitas, and Acary Bulle de Oliveira. "Pseudopolyneuritic form of amyotrophic lateral sclerosis: Marie-Patrikios type." International Journal of Case Reports and Images 13, no. 2 (September 21, 2022): 118–21. http://dx.doi.org/10.5348/101340z01mo2022cr.
Full textGeevasinga, Nimeshan, James Howells, Parvathi Menon, Mehdi van den Bos, Kazumoto Shibuya, José Manuel Matamala, Susanna B. Park, Karen Byth, Matthew C. Kiernan, and Steve Vucic. "Amyotrophic lateral sclerosis diagnostic index." Neurology 92, no. 6 (January 11, 2019): e536-e547. http://dx.doi.org/10.1212/wnl.0000000000006876.
Full textZwicker, Jocelyn, Danial Qureshi, Robert Talarico, Pierre Bourque, Mary Scott, Nicolas Chin-Yee, and Peter Tanuseputro. "Dying of amyotrophic lateral sclerosis." Neurology 93, no. 23 (October 31, 2019): e2083-e2093. http://dx.doi.org/10.1212/wnl.0000000000008582.
Full textGregory, Jenna M., Delphine Fagegaltier, Hemali Phatnani, and Matthew B. Harms. "Genetics of Amyotrophic Lateral Sclerosis." Current Genetic Medicine Reports 8, no. 4 (November 7, 2020): 121–31. http://dx.doi.org/10.1007/s40142-020-00194-8.
Full textVerhey, F. R. J., F. W. Vreeling, and J. Jolles. "Dementia and Amyotrophic Lateral Sclerosis." Acta Neuropsychiatrica 4, no. 1 (March 1992): 17–20. http://dx.doi.org/10.1017/s0924270800034967.
Full textDilliott, Allison A., Catherine M. Andary, Meaghan Stoltz, Andrey A. Petropavlovskiy, Sali M. K. Farhan, and Martin L. Duennwald. "DnaJC7 in Amyotrophic Lateral Sclerosis." International Journal of Molecular Sciences 23, no. 8 (April 7, 2022): 4076. http://dx.doi.org/10.3390/ijms23084076.
Full textOprisan, Alexandra L., and Bogdan Ovidiu Popescu. "Dysautonomia in Amyotrophic Lateral Sclerosis." International Journal of Molecular Sciences 24, no. 19 (October 5, 2023): 14927. http://dx.doi.org/10.3390/ijms241914927.
Full textDissertations / Theses on the topic "Amyotrophic lateral sclerosis, ALS"
Tjust, Anton. "Extraocular Muscles in Amyotrophic Lateral Sclerosis." Doctoral thesis, Umeå universitet, Anatomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-129638.
Full textAmyotrofisk lateralskleros (ALS) är en obotlig neurodegenerativ sjukdom som främst påverkar kroppens viljestyrda motoriska nervceller. ALS leder till förlamning, muskelförtvining och slutligen döden genom andningssvikt, vanligen inom tre till fem år efter sjukdomsdebuten. Av okända anledningar så bibehålls ögonmusklernas funktion mycket bättre vid ALS i jämförelse med andra muskler och är hos merparten av patienter i stort sett opåverkade. Ögonmusklerna är mycket specialiserade muskler som skiljer sig från andra muskler i kroppen på flera sätt, bland annat genom deras unika nervförsörjning och genom de satellitceller – muskelspecifika stamceller, som finns i dem. En ökad förståelse för hur dessa faktorer inverkar på ögonmusklernas motståndskraft vid ALS skulle kunna ge värdefulla ledtrådar till hur man skulle kunna sakta ned sjukdomens fortskridande i andra muskler vid ALS. Ögonmuskler och extremitetsmuskler från avlidna ALS-patienter och åldersmatchade friska kontroller, tillsammans med transgena möss med den sjukdomsalstrande mutationen SOD1G93A, studerades genom immunfluorescens och efterföljande mikroskopering. Antikroppar mot molekylerna Pax7, NCAM, MyoD, myogenin, Ki-67, laminin och dystrofin användes för att identifiera satellitceller och deras dotterceller i ögonmuskler och extremitetsmuskler. Antikroppar mot neurofilament och synaptofysin användes för att identifiera nerver och neuromuskulära synapser hos transgena SOD1-möss. Antikroppar mot toniska (tonic) och ryckande (twitch) muskelmyosinkedjor användes för att bestämma proportionen av och storleken på dessa typer av muskelfibrer i ögonmuskler från avlidna ALS-patienter och friska kontroller. Mängden satellitceller varierade mellan de främre och de mer bakre delarna i friska, humana ögonmuskler och var dubbelt så många i den främre delen av muskeln jämfört med den mellersta och bakre delen av muskeln. Celler som uttryckte satellitcellsmarkören Pax7 hittades även i icke-traditionella satellitcellspositioner i ögonmusklerna. Mängden satellitceller i ögonmusklerna från ALS-patienter var samma som hos friska kontroller. I extremitetsmusklerna hos ALS-patienter varierade mängden satellitceller mellan låga nivåer (liknande de hos friska åldrade, inaktiva individer) till höga nivåer, särskilt i muskler där sjukdomen fortskridit under lång tid. Dessutom varierade mängden satellitceller mellan övre och nedre extremiteter. Hos symptomatiska SOD1G93A-möss hade ögonmusklerna en mycket välbevarad innervation jämfört med bakbensmusklerna, där många neuromuskulära synapser saknade kontakt mellan nerven och motorändplattan. Proportionen muskelfibrer med toniska muskelmyosinkedjor var lägre hos ALS-patienter jämfört med friska kontroller. Denna minskning var tydligare hos patienter där sjukdomssymtomen hade debuterat i tugg- och ansiktsmuskulaturen – så kallad bulbär ALS. Dessutom fanns det i den här gruppen, men ingen annan studerad grupp, en stark korrelation mellan nedgången i toniska fibrer och patientens ålder. Värt att notera är att minskningen av toniska muskelfibrer saknade korrelation med hur länge patienten hade varit sjuk i ALS. Den generellt välbevarade innervationen i ögonmusklerna hos SOD1G93A-möss kan spegla distinkta inneboende egenskaper hos ögonmusklerna som är av vikt för bevarandet av ögonrörligheten vid ALS. Gällande satellitceller så antyder våra data att satellitceller och deras regenerativa kapacitet spelar en försumbar roll vid ALS i allmänhet och vid ögonmusklernas bevarande i synnerhet. Slutligen, även om ögonmuskler generellt är välbevarade vid ALS så är toniska muskelfibrer märkbart påverkade och detta kan spegla skillnader mellan olika nervcellsgruppers känslighet vid ALS.
LOFFREDA, ALESSIA. "RNA Metabolism alteration in amyotrophic lateral sclerosis models." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/81488.
Full textAROSIO, ALESSANDRO. "Study of transcriptional alterations in Amyotrophic Lateral Sclerosis." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2015. http://hdl.handle.net/10281/94396.
Full textRahmani, Kondori Nazanin. "Developing and testing therapies for Amyotrophic Lateral Sclerosis (ALS)." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/34340.
Full textFigueiredo, Joana Maria Serra de Oliveira Duarte. "The role of microRNAs in amyotrophic lateral sclerosis." Master's thesis, Faculdade de Ciências e Tecnologia, 2011. http://hdl.handle.net/10362/7991.
Full textMicroRNAs (miRNAs) are emerging as a primary mediator of gene regulation in many different cell types. There is increasing evidence that specific subsets of miRNA play a prominent role in the nervous system, both in development and in specific neurodegenerative diseases. This study aims to elucidate the role of microRNA in selective motor neuron death that is the hallmark of amyotrophic Lateral sclerosis (ALS). Pre-symptomatic time-point was chosen since the levels of miRNAs are highly likely to be altered as a secondary consequence of cell injury and death in ALS. Laser capture microdissection (LCM) was used to study miRNA profiles in motor neurons of spinal cord tissue from SOD1G93A mice, the best characterized model of ALS. In preliminary work, using miRNA specific chips we have identified 2 miRNAs which are dramatically upregulated before disease onset. In this study, high RNA quality was achieved from laser captured cells, which consist in a major advance towards obtaining meaningful results of these miRNAs expression in downstream applications. Despite LCM technology has become increasingly sophisticated; rapidly obtaining enough amount of starting material for downstream applications is still extremely challenging. The combination of this optimized technique with microarrays, followed by RT-qPCR may provide insights into potential contribution of microRNAs to progression of neurodegeneration of motor neurons in ALS.
Jonsson, P. Andreas. "Superoxide dismutase 1 and amyotrophic lateral sclerosis." Doctoral thesis, Umeå : Medical Biosciences, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-611.
Full textWootz, Hanna. "Amyotrophic Lateral Sclerosis – A Study in Transgenic Mice." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7342.
Full textEkegren, Titti. "Transmethylation, Polyamines and Apoptosis in Amyotrophic Lateral Sclerosis." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3952.
Full textZetterström, Per. "Misfolded superoxide dismutase-1 in amyotrophic lateral sclerosis." Doctoral thesis, Umeå universitet, Klinisk kemi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-43898.
Full textXu, Guang. "Identification of Novel Genetic Variations for Amyotrophic Lateral Sclerosis (ALS)." eScholarship@UMMS, 2018. https://escholarship.umassmed.edu/gsbs_diss/958.
Full textBooks on the topic "Amyotrophic lateral sclerosis, ALS"
National Institute of Neurological Disorders and Stroke (U.S.). Office of Communications and Public Liaison. ALS (Amyotrophic lateral sclerosis) fact sheet. Bethesda, MD: National Institutes of Health, 2010.
Find full textBehind those eyes: Our journey with ALS. Renfrew, Ont: General Store Publishing House, 2013.
Find full textRespiratory management of ALS: Amyotrophic lateral sclerosis. Sudbury, Mass: Jones and Bartlett, 2009.
Find full textGuion, Lee. Respiratory management of ALS: Amyotrophic lateral sclerosis. Sudbury, Mass: Jones and Bartlett, 2010.
Find full textAmyotrophic Lateral Sclerosis Society of Canada., ed. Resources for ALS healthcare providers. Toronto: The Society, 1994.
Find full textALS: Lou Gehrig's disease: Patient advocate. Riverside, CA: Health Scouter - Equity Press, 2009.
Find full textKoka, Halil. Bana ALS teşhisi koydular: Bir ALS hastasının umut dolu savaşı. İstanbul: Cinius, 2010.
Find full textStinton, William M. I choose to live: A journey through life with ALS. Gurnee, IL: Banbury Pub., 2003.
Find full textI choose to live: A journey through life with ALS. Gurnee, IL: Banbury Pub., 2003.
Find full textStinton, William M. I choose to live: A journey through life with ALS. Gurnee, IL: Banbury Pub., 2003.
Find full textBook chapters on the topic "Amyotrophic lateral sclerosis, ALS"
Iwata, M. "Severity Stages of ALS and Psychological Management." In Amyotrophic Lateral Sclerosis, 317–18. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_47.
Full textCesa-Bianchi, M., and F. Ravaccia. "Psychological Preparation of the Physician for ALS Patients." In Amyotrophic Lateral Sclerosis, 311–12. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_45.
Full textKüther, G., A. Struppler, and H. G. Lipinski. "Therapeutic Trials in ALS — The Design of a Protocol." In Amyotrophic Lateral Sclerosis, 265–76. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_38.
Full textFerro, F. M., G. Riefolo, D. A. Nesci, and S. Mazza. "Psychodynamic Aspects in Patients with Amyotrophic Lateral Sclerosis (ALS)." In Amyotrophic Lateral Sclerosis, 313–16. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_46.
Full textNorris, F. H., D. Holden, K. Kandal, and E. Stanley. "Home Nursing Care by Families for Severely Paralyzed ALS Patients." In Amyotrophic Lateral Sclerosis, 231–38. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_35.
Full textSilani, V., A. Pizzuti, L. M. Redaelli, R. Bassani, I. R. Causarano, M. Buscaglia, G. Zuliani, and G. Scarlato. "ALS Cerebrospinal Fluid Enhances Human Foetal Astroglial Cell Proliferation in Vitro." In Amyotrophic Lateral Sclerosis, 79–81. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_13.
Full textPinelli, P., L. Mazzini, G. Mora, F. Pisano, and A. Villani. "A Follow-Up Electromyographic Investigation of ALS Patients Treated with High Dosage Gangliosides." In Amyotrophic Lateral Sclerosis, 285–90. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_41.
Full textConradi, S., and L. O. Ronnevi. "Immunoglobulin-Mediated Cytotoxic Effect of ALS-Plasma Towards Erythrocytes: Reflexion of a Pathogenetic Mechanism?" In Amyotrophic Lateral Sclerosis, 7–13. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_2.
Full textSchieppati, M., A. Nardone, and M. Poloni. "Changes in the Normal Pattern of H-Reflex Inhibition During Muscle Release in ALS." In Amyotrophic Lateral Sclerosis, 155–58. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_26.
Full textIwata, M. "Clinico-Pathological Studies of Long Survival ALS Cases Maintained by Active Life-Support Measures." In Amyotrophic Lateral Sclerosis, 223–25. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7_33.
Full textConference papers on the topic "Amyotrophic lateral sclerosis, ALS"
Aquino, Letícia, Juliana Victor dos Santos, Jaqueline Donola Scandoleira, Jéssica Elen Gonçalves Nascimento, and Letícia Moraes de Aquino. "Telerehabilitation in Amyotrophic Lateral Sclerosis." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.528.
Full textNorel, Raquel, Mary Pietrowicz, Carla Agurto, Shay Rishoni, and Guillermo Cecchi. "Detection of Amyotrophic Lateral Sclerosis (ALS) via Acoustic Analysis." In Interspeech 2018. ISCA: ISCA, 2018. http://dx.doi.org/10.21437/interspeech.2018-2389.
Full textCUVELIER, Antoine, Elodie BARBARE, Catherine TARDIF, François SALACHAS, Didier HANNEQUIN, and Jean-François MUIR. "Predictive Factors Of Hypoventilation During Amyotrophic Lateral Sclerosis (ALS)." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3060.
Full textRyan, Claire, Pamela Shaw, and Pooja Shorey. "P120 A case of syphilitic amyotrophic lateral sclerosis (ALS)?" In BASHH 2023 Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/sextrans-bashh-2023.159.
Full textGoupille, P., S. Bouillon, P. Corcia, J. Brunais-Besse, S. Quennesson, and JP Valat. "THU0226 Amyotrophic lateral sclerosis (als): a trap for the rheumatologist." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.758.
Full textMarogna, M., and N. Balletto. "OP75 The decision making capacity in amyotrophic lateral sclerosis (ALS)." In ACP-I Congress Abstracts. British Medical Journal Publishing Group, 2019. http://dx.doi.org/10.1136/spcare-2019-acpicongressabs.75.
Full textPolverino, Francesca, Carlo Santoriello, Domenico Giannattasio, Filippo Andò, Andreas Jahn, Jose Luis Valera, Concetta De Rosa, Giuseppe Girbino, and Mario Polverino. "Respiratory Drive In Patients Affected By Amyotrophic Lateral Sclerosis (ALS)." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4204.
Full textCiorba, Cristina, Maria Luz Alonso Alvarez, Estrella Ordax Carbajo, Rodrigo delaRosa Giménez, Lourdes Martin Viñe, Maria Jose Bello Sebastian, Nieves Manchado Garcia, Montserrat Pamiés Solé, and Joaquin Terán Santos. "NIV (Non Invasive Ventilation) criteria and Amyotrophic Lateral Sclerosis (ALS) Survival." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2151.
Full textFernandes Palheiros Conde, Bebiana Da Conceição, Natália Martins, Elsa Matos, Inês Rodrigues, and João Carlos Winck. "Ventilatory support criteria in Amyotrophic Lateral Sclerosis (ALS) patients and outcomes." In ERS/ESRS Sleep and Breathing Conference 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/23120541.sleepandbreathing-2019.p25.
Full textViccaro, F., L. D'Antoni, M. E. Cardini, R. Flore, C. Tomsa, A. Lecci, A. Tramontano, and P. Palange. "Assessing diaphragm function by ultrasound in amyotrophic lateral sclerosis (ALS) patients." In ERS Respiratory Failure and Mechanical Ventilation Conference 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/23120541.rfmvc-2022.35.
Full textReports on the topic "Amyotrophic lateral sclerosis, ALS"
Santos, Ana Lúcia Yaeko da Silva, Deyse Mayara Rodrigues Caron, Livia Shirahige, and Abrahão Fontes Baptista. Alterations in Corticomotor Excitability in Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2023. http://dx.doi.org/10.37766/inplasy2023.5.0078.
Full textWackerman, Brooke L., B. L. Cox, K. L. Grayson, Shari L. Shanklin, and Wilson W. McGriff. Case Series Investigation of Amyotrophic Lateral Sclerosis (ALS) Among Former Kelly Air Force Base Workers. Fort Belvoir, VA: Defense Technical Information Center, April 2005. http://dx.doi.org/10.21236/ada437518.
Full textZhu, Qiaochu, Jin Zhou, Hai Huang, Jie Han, Biwei Cao, Dandan Xu, Yan Zhao, and Gang Chen. Risk factors associated with amyotrophic lateral sclerosis: a protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0118.
Full textAnklesaria, Pervin. Preclinical Development of Therapeutics for Amyotrophic Lateral Sclerosis. Fort Belvoir, VA: Defense Technical Information Center, October 2009. http://dx.doi.org/10.21236/ada541412.
Full textConnor, James R. Apo-Ferritin as a Therapeutic Treatment for Amyotrophic Lateral Sclerosis. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada567828.
Full textPrzedborski, Serge. Neuroprotective Small Molecules for the Treatment of Amyotrophic Lateral Sclerosis. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada567841.
Full textConnor, James R. Apo-Ferritin as a Therapeutic Treatment for Amyotrophic Lateral Sclerosis. Fort Belvoir, VA: Defense Technical Information Center, December 2013. http://dx.doi.org/10.21236/ada598852.
Full textGrill, Raymond J. Targeted Riluzole Delivery by Antioxidant Nanovectors for Treating Amyotrophic Lateral Sclerosis. Fort Belvoir, VA: Defense Technical Information Center, October 2014. http://dx.doi.org/10.21236/ada613439.
Full textGrill, Raymond J. Targeted Riluzole Delivery by Antioxidant Nanovectors for Treating Amyotrophic Lateral Sclerosis. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada598451.
Full textLoGrasso, Philip, and Serge Przedborski. c-jun-N-Terminal Kinase (JNK) for the Treatment of Amyotrophic Lateral Sclerosis. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada596507.
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