Dissertations / Theses on the topic 'AMMC'
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Maizeray, Arthur. "Protection et fonctionnalisation de surface d’alliages métalliques par un traitement duplex combinant des revêtements réalisés par le procédé cold-spray suivi de l’oxydation par plasma électrolytique." Electronic Thesis or Diss., Université de Lorraine, 2024. http://www.theses.fr/2024LORR0136.
Full textPlasma Electrolytic oxidation (PEO) is a process which enables the grow of a dense and protective oxide layer on light metals (Al, Mg, Ti). This process uses the dielectric breakdown of the oxide layer in a light alkaline electrolyte. In this study is this process coupled with the cold spray (CS) process. This combination enables to coat metals that are poorly treated by PEO directly and to modify the composition of the surface layer especially by combining different metals together of to produce composite such as AMMC. The aim of this study is to produce duplex coatings using CS and PEO and to understand in which way the composition of the top layer impact the behaviour of the PEO process and then to better understand the different regimes of this process. Different ceramics were used to show differences between arc and soft regime. The condition and the composition of the sprayed layer plays an important role on the obtained morphology and the soft regime obtention. The use of different composition oxides also enables us to bring to light some characteristics in the electrical discharge mechanisms occurring during the PEO process. A discharge nature evolution between the two regimes is supposed. The arc regimes present transversal discharges with important size, and this evolve to partially internal discharges in the oxide layer with lower size in the soft regime
Garcia, Marisol Peña. "Análise dos modelos AMMI bivariados." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-11022009-080418/.
Full textIs frequently nd in the studies the two way factor analysis, each factor with dierent number of levels, they conform a two way table of data, generally the analysis of the data is made with the analysis of variance - ANOVA, satisfying some assumptions, but there are some studies in which is very important the interaction, like the case of the improvement studies, where the objetive is select genotypes with optimum performance in dierents environments. The poor eciency in the genotypes and environment interaction (GE) analysis of the ANOVA can represents a problem for the researchers, that need to take advantage of the interaction. The additive main eects and multiplicative interactions model - AMMI, give advantages in the selection of genotypes when is compare with traditional methods, because give a better interaction (GE) analysis, also permit combine additive and multiplicative components in the same model, these models have demonstrated be ecient in the analysis with just one response variable but when there is more than one there is not a clear procedure to do the analysis. This work presents a analysis methodology for the bivariate AMMI models, doing individuals analysis in the response variables follow by the procrustes, which permit compare the results of the individuals analysis, and nally a conrmation of theses results with the multivariate analysis of variance - MANOVA. From the results can be concluded that the AMMI and the procrustes analysis give a good alternative for the bivariate AMMI models analysis.
Arif, Mehrunnessa, and Thérése Bergström. "Faktorer som påverkar mödrars beslut gällande valet att amma/inte amma sitt spädbarn : En litteraturstudie." Thesis, Högskolan i Gävle, Akademin för hälsa och arbetsliv, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-13428.
Full textAlata, Acuache Estefany Haydee, Chávez Mercy Elizabeth Calderón, Pastrana Alfredo Javier Mujica, Licas Lucia Patricia Ortiz, and Baltazar Jennifer Lesly Romero. "Ammy – asistencia virtual de salud reproductiva." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/652847.
Full textThroughout the life stage, women go through certain physical experiences to shape their femininity, such as menstruation, childbirth, lactation, pregnancy and menopause. Studies on the subject explain that women face complex diseases and others less severe, some diseases are: ovarian cancer, fibroids, polycystic ovaries, infections, among others. Being infections the main cause that leads women to the gynecologist, according to the Inem, in addition, it is known that almost 7 thousand women go to a gynecological consultation every month, of them about 70% go only for infections (Álvarez et al., 2017). For this reason, Ammy was created, a business idea that seeks to solve problems related to female reproductive health and that works through a mobile application. The service consists of providing menstrual monitoring with an alert of normality or abnormality of the menstrual cycle, with the option to enter the symptoms, thus alerting the user when her discomfort requires going to a gynecologist, after which, suggesting a list of doctors to make your medical appointments by the Ammy app. Although there are several foreign applications on the market, the truth is that none of them allow virtual medical consultations. In addition, there are thousands of women in Lima who are willing to pay for this service and for subscriptions to monitor their menstrual cycle. Without a doubt this business is innovative and very profitable, demonstrated in its profitability indicators of this work.
Trabajo de investigación
Jiang, Weimin. "Centennial AMOC variability : mechanism and impacts." Electronic Thesis or Diss., Sorbonne université, 2022. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2022SORUS193.pdf.
Full textThe Atlantic Meridional Overturning Circulation (AMOC) consists of a warm northward current on the surface and a cold southward branch in the deep. It brings tremendous heat into the mid-latitudes in the Northern Hemisphere and thus plays an important role in governing the climate of the North Atlantic region and beyond. This thesis investigates the driving mechanism and climate impacts of a centennial to multi-centennial variability of the AMOC. The AMOC intensity is modulated by the delayed freshwater exchanges through the Fram Strait between the Arctic Ocean and the North Atlantic. The thesis also investigates the climate impacts of this low-frequency AMOC variability and associated energy transport changes. The impacts of a strong AMOC mainly include a wide warming in the Northern Hemisphere, a northward displacement of the intertropical convergence zone and more precipitations in the Northern mid-latitudes. The enhanced northward oceanic energy transport induced by intensified AMOC is compensated by the anomalous southward energy transport in the atmosphere, which leads to climate variations. This response in the atmosphere is damped by the Indo-Pacific Ocean
Alonso, Louro Noemí. "Caracterización molecular de los genes blaAmpC cromosómicos y adquiridos en aislados clínicos de Escherichia coli en el área de Barcelona." Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/285112.
Full textEscherichia coli has a chromosomal blaAmpC gene that is expressed constitutively at low level due to the presence of a weak promoter and an attenuator. Under these conditions, this gene does not confer resistance to beta-lactams. However, this chromosomal gene may be overproduced due to mutations in the promoter/attenuator region (cAmpC). Additionally, E. coli may also acquire blaAmpC genes (aAmpC), namely CMY, DHA, ACC, FOX, MOX, ACT, MIR, LAT and CFE. Both mechanisms (cAmpC and aAmpC) confer resistance to penicillins, cephalosporins, cephamycins and aztreonam. In contrast to the range of phenotypic methods available for extended-spectrum beta-lactamases (ESBLs), no standardized methods are available to detect AmpC beta-lactamases. There is a paucity of reports on the epidemiology and clinical features associated with infections caused by AmpC-producing E. coli. Furthermore, these isolates frequently present co-resistance to other families of antibiotics, converting treatment of these infections into a clinical challenge. A multicentric study was performed to analyse E. coli isolates with a resistance pattern compatible with the production of AmpC. Isolates were obtained from Consorci Sanitari de Terrassa, Hospital Universitario Mútua de Terrassa and Hospital de la Santa Creu i Sant Pau (Barcelona, Spain) between June 2010 and November 2011. The aims of this study were: 1) to determine the prevalence of AmpC-producing E. coli isolates; 2), to identify acquired blaAmpC genes and the mutations involved in the overproduction of the chromosomal blaAmpC gene; and 3) to describe the population structure and patterns of resistance. A total of 240 strains were analysed. Of these, 75% were aAmpC-carriers and the remaining were cAmpC-overproducers. CMY-2 was the predominant enzyme, followed by DHA-1. Most cAmpC-overproducers had mutations that yielded an alternate displaced promoter and caused an increase of blaAmpC expression (average increase of expression 72.5). Two other different mutational patterns were found: a modified spacer region in the promoter and a modified attenuator (the average increase of expression was 19.9 and 5.8, respectively). Analysis of the phylogenetic groups allowed to gain knowledge of the population structure. Of all aAmpC isolates, 60% belonged to the phylogenetic groups B2, D, E and F. Among cAmpC overproducers, 82% of the isolates bearing a displaced promoter belonged to groups A, B1 and C. All the isolates with modified attenuator regions and 67% of the isolates with modified spacer regions belonged to groups B2, D, E and F. As it happens in ESBL-carrying strains, the plasmids carrying blaAmpC genes may also carry other genes, conferring resistance to other families of antibiotics. In the present study, the percentage of resistance to nalidixic acid, streptomycin, ciprofloxacin and trimethoprim-sulfamethoxazole was 79%, 62%, 57.5% and 44%, respectively. Plasmid-mediated quinolone resistance determinants (PMQR) were detected in 30% of the aAmpC isolates and 11% of the cAmpC isolates. Among aAmpC isolates, the most predominant PMQR was qnrB4 (always in blaDHA-1 carriers), followed by aac(6’)-Ib-cr. Among cAmpC isolates, the predominant PMQR was aac(6’)-Ib-cr. The increase in the prevalence of these enzymes is due to the spread of genes through horizontal transfer. The analysis of plasmids showed that IncI1 and IncF were the main replicons involved. IncI1 and IncF were related to blaCMY-2 and blaDHA-1, respectively. The pMLST analysis of plasmids revealed a large genetic variability. IncI1/ST12 was the predominant sequence type. Other sequence types belonging to the same incompatibility group were IncI1/ST26, IncI1/ST55, IncI1/ST94 and IncI1/ST134, the latter being first described in this study. Regarding IncF, each plasmid corresponded to a different sequence type.
Sunnvius, Louise, and Hanna Angermund. "Mammors tillit till sin förmåga att amma." Thesis, Högskolan i Gävle, Medicin- och vårdvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-25464.
Full textBackground: The number of breastfeeding mothers is reducing in Sweden, a contributing factor to the decrease can be the lack of confidence in their ability to breastfeed. It is important to identify mothers with low confidence in their ability to breastfeed in order to make it possible to reverse the declining number of breastfeeding mothers, and for the primary care nurse to strengthen the woman in the role of a breastfeeding mother. Aim: The purpose of the study was to describe and compare mothers’ confidence in their ability to breastfeed. Method: With the survey, the breastfeeding self-efficacy scale - short form (BSES-SF) that measures trust in its ability to breastfeed, data was collected to identify mothers with low or high confidence. Results: The mothers’ of the age groups 18-25 years and 35-45 years, regardless of the age of the child, estimated the lowest confidence in their ability to breastfeed that they could always perform each breastfeeding in a satisfactory manner. The highest ranked trust of all mothers, regardless of their own age or child's age, was that they could always come to the conclusion that they would want continue to breastfeed. Mothers who breastfeed children in the higher age group, 10 weeks (w) – 17 w + 6 days (d), estimated in total according to BSES-SF, their confidence in breastfeeding significantly higher than mothers who breastfeed children between 0 w – 9 w + 6 d. Conclusion: The mothers’ in this study who breastfeed babies between 10 w – 17 w + 6 d estimate their ability to breastfeed higher than the mothers who breastfeed children between 0 w – 9 w + 6 d.
Vásquez, Aguilar Raquel. "Att amma är mitt val : En intervjustudie." Thesis, Högskolan i Borås, Institutionen för Vårdvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-16525.
Full textProgram: Barnmorskeutbildning
Pennafiel, Uilson Ruas. "AMDC : analisador microcontrolado de desfibriladores e cardioversores." [s.n.], 1998. http://repositorio.unicamp.br/jspui/handle/REPOSIP/259888.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação
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Resumo: O funcionamento eficaz e seguro de equipamentos médicos, tais como desfibriladores e cardioversores, requer manutenção preventiva e corretiva que, em muitos casos, precisa ser realizada próximo à unidade hospitalar onde os equipamentos são utilizados. Este trabalho descreve o desenvolvimento de um analisador microcontrolado de desfibriladores e cardioversores, que atende aos requisitos de versatilidade de um instrumento de calibração, a um custo relativamente baixo. O analisador é portátil e auto-suficiente (pode ser alimentado e carrega automaticamente suas baterias) e mede os seguintes parâmetros do pulso desfibrilatório: 1) energia direta e reversa (em 4 escalas, variando de 2 a 1.000J); 2) amplitude máxima de tensão e corrente das parcelas positiva e negativa (até 6 kV); 3) taxas de subida tR, t50 e t10 da norma ANSI/AAMI-DF2 (de 100ms até 200 ms); e 4) duração (de 100ms até 200 ms). A forma de onda do pulso desfibrilatório é apresentada num display tipo LCD de 256x64 pixels e todos os parâmetros aferidos podem ser impressos ou transmitidos a um dispositivo de registro. Uma carga resistiva de entrada (de 25, 50, 75, 100 ou 125 O), selecionada pelo usuário operador, simula a impedância transtorácica do corpo humano. Para testar cardioversores, o analisador simula o complexo QRS ou aguarda um sinal de sincronismo externo para medir o tempo de resposta (atraso entre o sinal de sincronismo e a cardioversão). Ensaios em laboratório com instrumentos calibrados (osciloscópio e geradores) e com destibriladores / cardioversores demonstraram um bom desempenho do protótipo
Abstract: The effectiveness and safety of medical devices, such as defibrillators and cardioverters, require preventive maintenance and repair, which should be carried out in many instances near the hospital unit where the devices are being used. This work describes the development of a microcontrolled analyzer, which fulfills the requirements of a calibrating equipment, at a relatively low cost. The analyzer is powered by batteries, is self-sufficient and measures the following defibrillator output pulse parameters: 1) direct and reverse energy (four ranges, from 2 to 1,000J); 2) direct and reverse peak voltage and current (up to 6 kV); 3) ANSI/AAMI-DF2 tR, t50 and t10 rise rate (from 100ms to 200 ms); and 4) pulse width (from 100ms to 200ms). The defibrillating pulse waveform is shown on a 256x64-pixel LCD display. All measured parameters can be printed or transmitted to a record device. An internal resistive load (of 25, 50, 75, 100 or 125 O) simulates the transthoracic impedance of the human body. To test cardioverters, the analyzer simulates the QRS complex and measures the response time (delay between synchronous and cardioverter pulses). Laboratory tests performed with calibrated instruments (oscilloscope and generators) and field tests with different types of defibrillators have shown good performance of the prototype
Mestrado
Automação
Mestre em Engenharia Elétrica
Assis, Tatiana Oliveira Gonçalves de. "Comparação dos modelos AMMI e AMMI ponderado na análise da interação genótipo x ambiente e interação QTL x ambiente." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-14122015-100356/.
Full textThe genetic characteristics of crops can be influenced by the environment, interfering with productivity. This research intends to understand the genotype-by-environment interaction(IGA) and quantitative trait locus (QTL)-by-environment interection (IQA), in order to provide tools that can improve productivity. That the Additive Main Effects and Multiplicative Interactions (AMMI) model, has been widely used to study and understand these interactions and has shown to provide good interpretations of both IGA and IQA, as well as QTL detection. In order to take into account of the heterogeneity of error variance over the environments, a generalization of the AMMI model is used, the weighted AMMI or W-AMMI. In this study, observing the data resulting from an experiment with 9 maize genotypes conducted in 20 environments and 4 blocks, was used to compare the results between the AMMI and W-AMMI models. A second set of data, resulting a cross between the barley varieties Harrington and TR306, with 141 genotypes conducted in 12 environments, was used to compare the AMMI and two versions of the W-AMMI (equal weighs per row; and equal weights per column) models in terms of IGA, IQA and QTL detection.
Silva, Maria Joseane Cruz da. "Imputação AMMI Bootstrap Não-paramétrico em dados multiambientais." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-18052017-183043/.
Full textIn multienvironment studies, the process of recommendation of genotypes with higher production and the determination of stable environments are of utmost importance for plant breeders. However, when there is missing of genotype in one or more environments this process show difficulties. Therefore, this procedure depends on statistical methods that complete data matrix requered. Since 1976 various mathematical and statistical study, continually, one way of dealing with the loss of information on data multienvironments, seeking to obtain a method that estimate, precisely, the missing units without loss of information. In this way, the purpose of this study is develop a new method of apportionment based on the methodology AMMI doing reamostragens bootstrap nonparametric in the array of means of genotype x environment interaction (GE). For the study of simulation was considered the data set concerning the origin of S. Mexico City - Mt Pandanus - QLD (14,420) of Eucalyptus grandis collected in Australia in 1983. It was performed two studies of simulation. The first performed 2000 resampling on the lines of the interaction matrix G X E, for two percentages of missing data (10% and 20%). The second simulation study considered 200 replicates in the missing data set (10 %) and three different models of IMAMMI-BNP: AMAMMI0-BNP, which considers only the main effects of the AMMI model; IAMMI1-BNP and IAMMI2-BNP which considers one and two axes multiplied by the AMMI model, respectively. In general, according to the comparison methods, the imputation method proposed in the two simulation studies provided imputed values similar to the originals. Considering the simulation studies with 10 % loss, the efficiency of the proposed imputation method was better when using the IAMMI2-BNP model (with two multiplicative axes). The Wilcoxon test of the orders showed that the values imputed had no influence on the mean estimate, indicating that mean values of the data imputed from each environment were statistically similar to the original mean values.
Guillon, Hélène. "Activité carbapénémase des β-lactamases de type AmpC." Amiens, 2013. http://www.theses.fr/2013AMIED003.
Full textOwing to several clinical reports, it appears that AmpC-type β-lactamases (cephalosporinases) account frequently for carbapenem resistance in Enterobacteriaceae. The aim of this study was to perform a phenotypic, biochemical, and molecular characterization of the carbapenem-hydrolyzing activity of AmpC-type β-lactamases. First of all, the genes encoding the five main plasmid-mediated AmpC β-lactamases were cloned and transferred into the porin-deficient Escherichia coli HB4 strain. Phenotypic and molecular comparison of the recombinant strains revealed that only CMY-2, ACT-1, and DHA-1 conferred resistance to carbapenems and had an asparagine residue at position 346 (Asn 346), located in the vicinity of the active site. Site-directed mutagenesis experiments were performed to replace the Asn 346 residue of CMY-2 β-lactamase by amino acids differing in size, charge, and polarity. It confirmed the contribution of Asn 346 to the carbapenem-hydrolysing activity of cephalosporinases. Biochemical characterization of three variants revealed that Asn 346 assisted the binding of imipenem. The analysis of the carbapenem-hydrolyzing activity of chromosomal extended-spectrum AmpC β-lactamases (ESAC) constitutes the second part of this thesis. Sequencing, cloning and biochemical characterization of a novel ESAC produced by an ertapenem-resistant E. Coli clinical isolate demonstrated that the extension of the hydrolysis spectrum of cephalosporinases, which was due to increased affinity, may also contribute to carbapenem resistance
Brandão, Catarina Salomé da Cruz. "Aplicação de testes fenotípicos para deteção de AmpC." Master's thesis, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/11561.
Full textA seletividade, eficácia e espetro de ação dos antibióticos β-lactâmicos faz deles a classe de antimicrobianos mais comummente prescritos para o tratamento de infeções causadas por enterobactérias. As β-lactamases surgem como um dos principais mecanismos de resistência microbiano aos antibióticos β-lactâmicos, onde as β-lactamases do tipo AmpC se assumem como clinicamente relevantes, ao conferir resistência à maioria das penicilinas, cefalosporinas e combinações de β-lactâmico/inibidor de β-lactamase. A dificuldade na deteção deste mecanismo de resistência antimicrobiana, associada a múltiplos genes de resistência de rápida evolução e transmissão bem como a inexistência, até à data, de guidelines de referência para a deteção de AmpC constitui um desafio no diagnóstico para o laboratório de microbiologia, que carece de uma estratégia definida para a pesquisa destas enzimas, a ser implementada na rotina hospitalar. São vários os métodos propostos para a deteção destas enzimas, quer genotípicos, quer fenotípicos. No último grupo podem destacar-se os que detetam a atividade AmpC em extratos enzimáticos e os que avaliam o efeito induzido pelos inibidores de AmpC sobre as enzimas. No presente trabalho foram usados discos de cefoxitina, cujo resultado foi comparado com um kit da casa comercial MAST, para a pesquisa e deteção de AmpC em 50 isolados bacterianos. O uso de discos de cefoxitina (30μg) para o screening destas enzimas mostrou-se sensível e específico. O teste fenotípico confirmatório da MAST revelou-se uma ferramenta útil na confirmação da presença destas enzimas. No contexto deste estudo, ambos os testes foram validados para introdução na rotina hospitalar.
The selectivity, efficacy and spectrum of action of β-lactam antibiotics make them the class of antibiotics most commonly prescribed to treat infections caused by Enterobacteriaceae. The β-lactamases emerged as one of the major mechanisms of microbial resistance to β-lactam antibiotics, where the AmpC β-lactamases themselves are clinically relevant, conferring resistance to most penicillins, cephalosporins and combinations of β-lactam/β-lactamase inhibitor. Detecting this mechanism of antimicrobial resistance can be difficult because it is associated with multiple resistance genes. Moreover, the lack of guidelines for detection of AmpC is a challenge in a microbiology laboratory. Therefore a strategy to detect this type of enzymes is needed, to be implemented in the daily routine. There are several methods proposed for the detection of the enzyme, either genotypic or phenotypic. In the latter group can be underlined those that detect the activity of AmpC in enzyme extracts and those who evaluate the effect induced by inhibitors on AmpC enzymes. In the present study, the results obtained with cefoxitin disks were compared to a commercial kit (MAST), for screening and detection of AmpC β-lactamases, in 50 bacterial isolates. The use of cefoxitin discs (30μg) for the screening test was sensitive and specific. The confirmatory test of MAST has proved to be a useful tool in confirming the presence of these enzymes. In the context of this research, both tests have been validated to be performed in the hospital daily routine.
Schulz, Stefan E. "AMC 2015 – Advanced Metallization Conference." Universitätsverlag der Technischen Universität Chemnitz, 2016. https://monarch.qucosa.de/id/qucosa%3A20503.
Full textSpecker, Silvia. "Klonierung von Cytochrom-P450-abhängigen Monooxygenasen aus Ammi majus L. und funktionelle Expression der Zimtsäure 4-Hydroxylase." [S.l. : s.n.], 2004. http://archiv.ub.uni-marburg.de/diss/z2004/0072/.
Full textMeschin, Pierre. "Régulations monoaminergiques AMPc-dépendantes du coeur sain et pathologique." Thesis, Montpellier 1, 2014. http://www.theses.fr/2014MON1T010.
Full textCardiac function is tightly regulated by hormones such as monoamines which are substantial modulators of cardiac activity (chronotropy and inotropy). These hormones, derived from aromatic amino acids, maintain myocardial activity in a physiological range and allow the cardiac adaptation to environmental conditions. The cellular receptors to monoamines are coupled to signaling pathways involving a cyclic nucleotide, cAMP, and modulate cardiac activity by phosphorylating several key proteins of calcium handling (L-type calcium channel, RyR2 or phospholamban) by the cAMP-dependent protein kinase A. Deregulation of monoamines in pathological conditions such as heart failure (HF) or during antidepressanttreatment leads to a hyperstimulation of their specific receptors. It therefore induces alterations of the cAMP signaling pathway and calcium handling leading to the occurrence of proarrhythmogenic ectopic cellular events known as afterdepolarizations. These dysfunctions in cellular contractility and calcium handling may cause tissue arrhythmias andeven sudden cardiac death. Calcium handling alterations leading to cardiac arrhythmias remain a clinically relevant issue despite the current therapeutical approaches (!-blockers, angiotensin-converting-enzyme inhibitors) which slow the post-ischemic myocardial remodeling and thus represent an active target in the cardiovascular research field. Rycals, RyR2 pharmacological stabilisers, are a new approach to prevent these alterations. In this work, we focused on the two major monoaminergic cAMP-dependent pathways in the heart, the adrenergic and serotoninergic pathways. In the first part of this work, we aimed to evaluate the potential benefits of a new Rycal, S44121, on cellular and tissue arrhythmias occurrence in post-myocardial infarction rat model. These effects were compared to those of the well-known !-blocker, metoprolol. This study failed to show any strong benefit of S44121 but confirmed the cardioprotection associated with the metoprolol use. In a second part of the work presented here, we aimed to evaluate the potential involvement of the S100A10 protein in the modulation of the cardiac serotonin receptor 4 pathway (5-HT4R) in physiological conditions or during HF. This original study unraveled for the first time a new role for S100A10 in the healthy heart by revealing a functional 5-HT4R pathway when S100A10 expression is induced by neurotrophins such as brain-derived neurotrophic factor or by antidepressant drugs such as imipramine. However, we failed to conclude on a direct evidence for a role of S100A10 in the modulation of the 5-HT4R pathway in the failingheart
Wimmer, Emily [Verfasser]. "Mittelfristige Ergebnisse der autologen matrixinduzierten Chondrogenese (AMIC) / Emily Wimmer." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2011. http://d-nb.info/1009670387/34.
Full textChadia, Elharbiti, and Engdahl Sofie. "Mammors upplevelser av sjukvårdens och omgivningens bemötande vid val av att inte amma eller sluta amma i ett tidigt skede : En deskriptiv kvalitativ studie." Thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-353597.
Full textEsnault, Stéphane. "Expression differentielle des cytokines de type 1/type 2 chez le sujet allergique et, implication de la voie ampc dans les mecanismes de regulation." Reims, 1996. http://www.theses.fr/1996REIMP210.
Full textHehmann, Marc. "Klonierung von O-Methyltransferasen zur Furanocumarinbiosynthese in Ammi majus L." [S.l.] : [s.n.], 2004. http://archiv.ub.uni-marburg.de/diss/z2004/0156/.
Full textCorrêa, Adriana Cristina Giusti. "Recuperação de documentos baseados em informação semântica no ambiente AMMO." Universidade Federal de São Carlos, 2003. https://repositorio.ufscar.br/handle/ufscar/522.
Full textThis study presents techniques used for extracting semantic information from texts and strategies for semantic information-based document retrieval. These techniques and strategies have been adopted so as to develop a Document Manipulation System based on Semantic Information. Previously established values of similarity and relevance are used in the document retrieval process.. The organization of semantic information, user interfaces, manipulation of imprecise information and the extraction and retrieval mechanism are discussed. The impreciseness in the semantic information is treated through similarity values in order to compare the query´spredicates with the database results. Relevance values specified for the query´s predicates have been used to classify the resulting documents. A prototype of the system has been developed. This prototype can be incorporated into the AMMO environment (Authoring and Manipulation of Multimedia Objects), whose aim is to provide resources for creating, storing and manipulating multimedia applications.
Neste trabalho são apresentadas técnicas utilizadas na extração de informação semântica de textos e estratégias para recuperação de documentos baseada em informação semântica, que foram adotadas para o desenvolvimento de um Sistema para Manipulação de Documentos baseada em Informação Semântica. Para a recuperação de documentos são considerados valores de similaridade e relevância estabelecidos. A organização da informação semântica, as interfaces com o usuário, a manipulação das informações imprecisas, o mecanismo de extração e recuperação são discutidos. A imprecisão inerente à informação semântica é tratada através de valores de similaridade para comparar os termos requeridos na consulta e os consultados no banco de dados. Os valores de relevância especificados para os termos envolvidos na consulta são utilizados para classificar os documentos resultantes. Foi desenvolvido um protótipo do sistema, que pode ser incorporado ao ambiente AMMO (Authoring and Manipulation of Multimedia Objects), que tem por objetivo fornecer recursos para a criação, armazenamento e manipulação de aplicações multimídia.
Djossou, Agboadannon Koumagnon Alfred. "African women's empowerment : a study in Amma Darko's selected novels." Thesis, Le Mans, 2018. http://www.theses.fr/2018LEMA3008/document.
Full textThis thesis adresses the question of wether African female novelists have a different view in portraying their female characters ans it investigates on wether their fiction can inspire women'e empowerment. It examines the influence of culture and customs in the selected novels by Amma Darko. Focusing on thse novels of the third generation, the thesis explores mods of memories, trauma and history writing and highlights the way she represents, reaffirms ans re-positions women in her creative writings to empower them in society.It analyses the solutions o issues raised through the novelist's choracters. This thesis finally shows how much Amma Darko' is at the forefront of a committed African litterature written by African women with an ideological point of view
Westergren, Ylva. "Upplevelser av att amma på offentlig plats : En kvalitativ intervjustudie." Thesis, Linnéuniversitetet, Institutionen för kulturvetenskaper (KV), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-49286.
Full textDaradda, Lidiane Fernanda Rocha. "Mensuração do desempenho estratégico no terceiro setor: o caso AMIC." Universidade Estadual do Oeste do Paraná, 2018. http://tede.unioeste.br/handle/tede/3667.
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The theme of this study refers to the use of the Strategic Performance Measurement System (SPMS) in organizations of the third sector, which have required performance mechanisms that apply to the management. Therefore, this research aimed to investigate how the Strategic Performance Measurement System can contribute to strategic planning in the third sector by means of performance indicators, justifying the application of SPMS in this segment that is differentiated and poorly explored. The theoretical reference was based on the Third Sector, Strategic Planning, Strategic Performance Measurement System and Previous Studies. For this purpose, a unique case study and action research with a qualitative focus were performed at AMIC. Data collection consisted of a focus group, questionnaires, documents, organizational records and participant observation, using the case study´s protocol and triangulation of research sources. The results confirmed the research propositions and the findings of the literature, and it was verified that the strategic planning allows the use of the measurement system in the organizations of the third sector through the elaboration of the SWOT Analysis and action plan; the evaluation of strategy implementation contributes to the performance of third sector organizations through the control, monitoring, identified gaps and positive influence on performance; and the elaboration of the own measurement model uses financial and non-financial indicators for the management in the third sector based on strategic direction. Thus, as result of the intervention, the management of the strategic actions was achieved, the implementation of the strategy generated benefits to the performance and the composition of a coherent set of performance measures were obtained. The main contributions show that the SPMS can be used in nonprofit organizations, in addition to those that aim for profit and make use of it, as well as contribute to the theoretical gap on appropriated performance measures to the third sector.
O tema desta pesquisa refere-se ao uso do Sistema de Mensuração de Desempenho Estratégico (Strategic Performance Measurement System - SPMS) em organizações do terceiro setor, as quais têm requerido mecanismos de desempenho que se apliquem a gestão. Dessa forma, este estudo teve por objetivo investigar como o Sistema de Mensuração de Desempenho Estratégico pode contribuir ao planejamento estratégico no terceiro setor por meio de indicadores de desempenho, justificando-se pela aplicação do SPMS nesse segmento diferenciado e pouco explorado. O referencial teórico embasou-se no Terceiro Setor, Planejamento Estratégico, Sistema de Mensuração do Desempenho Estratégico e Estudos Anteriores. Para tanto, um estudo de caso único e pesquisa-ação com enfoque qualitativo foi realizado na AMIC - Associação de Microempresas e Empresas de Pequeno Porte do Oeste do Paraná. A coleta de dados valeu-se de grupo focal, questionários, documentos, registros organizacionais e observação participante, com utilização do protocolo do estudo de caso e triangulação das fontes de pesquisa. Os resultados confirmaram as proposições de pesquisa e os achados da literatura, verificando-se que o planejamento estratégico possibilita a utilização do sistema de mensuração nas organizações do terceiro setor por meio da elaboração da Análise SWOT e plano de ação; a avaliação da implementação da estratégia contribui ao desempenho das organizações do terceiro setor mediante o controle, monitoramento, lacunas identificadas e influência positiva sobre o desempenho; e a elaboração do modelo próprio de mensuração utiliza indicadores financeiros e não financeiros para a gestão no terceiro setor pautados no direcionamento da estratégia. Portanto, como resultado da intervenção obteve-se o gerenciamento das ações estratégicas, benefícios gerados ao desempenho pela implementação da estratégia e composição de um conjunto coerente de medidas de desempenho. As principais contribuições apontam que o SPMS pode ser utilizado nas entidades sem fins lucrativos, além daquelas que visam lucro e fazem uso do mesmo, bem como contribui a lacuna teórica sobre as medidas de desempenho adequadas ao terceiro setor.
Papproth, Eckhard. "Conception et traitement de signal pour les systèmes radiomobiles AMRC /." Paris : École nationale supérieure des télécommunications, 1996. http://catalogue.bnf.fr/ark:/12148/cb35855706p.
Full textMkalaluh, Sabreen [Verfasser]. "Langfristige Ergebnisse der Autologen Matrix-Induzierten Chondrogenese (AMIC) / Sabreen Mkalaluh." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2015. http://d-nb.info/1079730265/34.
Full textSaunois, Marielle. "Bilan de l'ozone troposphérique en Afrique : Apport du programme AMMA-Chimie." Phd thesis, Université Paul Sabatier - Toulouse III, 2009. http://tel.archives-ouvertes.fr/tel-00421963.
Full textIvars, i. Santacreu David. "Tabaco, estrés oxidativo e inflamación en vías aéreas. Papel del AMPc." Doctoral thesis, Universitat de València, 2010. http://hdl.handle.net/10803/62139.
Full textChronic Obstructive Pulmonary Disease (COPD) is a pathological state characterised by an irreversible and progressive airway obstruction where tobacco smoke is the main cause of disease progression. Mucus hypersecretion is a distinctive feature in COPD patients; moreover oxidative stress plays a key role in the pathology. NADPH oxidase system is involved in this oxidative stress. Currently, selective inhibition of phosphodiesterase (PDE) 4 appears to be promising in COPD management, due to PDE4 are expressed in distinct cellular types involved in inflammatory and immunomodulatory responses. Intracellular cyclic AMP (cAMP) levels are augmented as a consequence of PDE4 inhibition. In the present thesis we aimed to study the characterisation of mechanisms by which NADPH oxidase system activation is induced in response to cigarette smoke extract, studying further AMPc involvement in the process. Results shown that NADPH oxidase system was induced in response to cigarrete smoke extract, which generates an oxidative stress that leads to activation of epidermal growth factor receptor (EGFR) , and mucin overexpression was produced in a reduced AMPc levels dependent process in consequence. Blocking NADPH oxidase activity using a nonspecific inhibitor of the system, diphenileneidonium (DPI), N-acetylcisteine (NAC) as antioxidant, as well as piclamilast as a PDE4 selective inhibitor (via a cAMP level increase), inhibited mucin expression induction at different levels in response to NADPH oxidase system activation dependent by cigarette smoke extract.
Araújo, Lúcio Borges de. "Métodos de correção de autovalores e regressão isotônica nos modelos AMMI." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-06032006-170637/.
Full textIn agricultural research is common to analyse groups of experiments. In many cases, the researcher intends to generalize results to general conditions of areas and/or evaluate the responses of several genotypes (treatments) in several environments (places and/or years). When a group of experiments is planned for several places it is necessary to consider the of design in each place and the combinations of the genotypes with the places (the interaction of genotype × environment). The observed data can be organized in an array. There are several methods of analysis and interpretation for the genotype × environment interaction from a group of genotype tested in several environments. These methods include AMMI models (additive main effect and multiplicative interaction models). As the name says it is a uni-multivariate method, that includes an analysis of variance for the main effects (the effects of the genotypes (G) and environments (E)) and assumes multiplicative effects for the genotype × environment interaction, using a singular value decomposition (DVS). This method estimates the eigenvalues and eigenvectors deriving from the matrix of genotype × environment interaction. Araújo and Dias (2005) found an overestimation and underestimation problem with the eigenvalues in the conventional way. To correct these problems Muirhead (1987) presents three methods to correct the eigenvalues from covariance the matrix and noted that these do not always maintain the order of values. The author suggested the use of isotonic regression to correct the eigenvalues, using an algorithm presented by Lin and Pearlman (1985). The results indicated that: The isotonic regression with the algorithm is necessary and it showed very important in all groups of data; There was a reduction in the number of significant components to be kept in the models and the order that the AMMI model selected is more parsimonious when any of the correction methods is used; The method 2 has the smallest rate of correction to the sum of squares of the genotype × environment interaction and method 3 has the largest correction rate; The measure RMSPDPRESS was smallest when method of correction 2 was used. The method of correction 3 has the largest values for RMSPDPRESS; Method 2 was also better when the interest was to verify the gain in number of replicates, and this benefit was always close to 3 replicates. The method 3 gives the smaller gain in the number of replicates, of around two replicates.
Lavoranti, Osmir José. "Estabilidade e adaptabilidade fenotípica através da reamostragem "Bootstrap" no modelo AMMI." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-22102003-160700/.
Full textReliable evaluation of the stability of genotypes and environment is of prime concern to plant breeders, who have Undertaken much research into the development of methods for studying in detail the structure of genotype-environment interaction. The lack of a comprehensive analysis of the structure of the GEI interaction has been a stumbling block to the recommendation of cultivars. Traditionally, the analysis of that structure was superficial and stopped short of detailing the efects of the complexity of the interaction. However, recent advances in computer science have allowed the development of interactive systems of data processing with fast and precise algorithms. Consequently, statistical methods are being developed to study in detail the structure and stability of GEI interaction. At the moment, the Additive Main Efects and Multiplicative Interaction (AMMI) Model promises to be more eficient than the usual analyses in the interpretation and understanding of the GEI interaction. The main drawbacks of the AMMI methodology are the dificulty of interpreting the interaction when there is a poor explanation of the first principal component; the dificulty of determining low scores, which relates to the statistical stability of the genotypes and/or environments; and the lack of presentation of the pattern of response of the genotype, which characterizes the adaptability patterns of the groups formed through significant parameters. Thus care needs to be exercised in the interpretation. The present contribution proposes the use of bootstrap re-sampling in the AMMI Model, and applies it to obtain both a graphical and a numerical analysis of the phenotypic stability and adaptability of 75 progenies of Eucalyptus grandis from Australia that were planted in seven environments in the South and Southeast regions of Brazil. The results show diderential behavior of genotypes and environments, the genotype x environment interaction being significant (p value < 0.01). The interpretation of the phenotypic stability through graphical analysis of the AMMI biplot is better understood with the aid of the bootstrap. The bootstrap coeficient of stability based on the squared Mahalanobis distance of the scores bootstrap, shows that genotypes and environments can be diferentiated in terms of their stabilities. The AMMI bootstrap proposal thus provides better and more precise predictions of phenotypic stability and adaptability of the geno- types than the traditional AMMI analysis, and eliminates the doubts related to the identification of the low scores.
Godoi, Débora Robert de. "Estabilidade em análise de agrupamento via modelo AMMI com reamostragem \"bootstrap\"." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-13112013-143342/.
Full textThe objective of this work is to propose a new interpretation methodology of clustering methods for vegetation data stability, using the AMMI and bootstrap methodology, to gain reliability in the clusters formed. The database used is from the Departament of Genetics of Luiz de Queiroz College of Agriculture, aiming soybean yield. Firstly AMMI is applied, then the Euclidian distance matrix is estimated - based on the original data and on the acquired by the bootstrap method - for the application of clustering methods (nearest neighbor, furthest neighbor, average linkage, centroid , median and Ward). In order to assess the validity of clusters formed the cophenetic correlation coefficient is used, and the Mantel test, in order to show the empirical distribution of the cophenetic correlation coefficients. The clusters obtained by different methods are, in most cases, quite similar, indicating that in principle, any of these methods would be suitable for the representation. The method that presents discrepant results (for both the original and bootstrap method obtained data) - on the dendrogram graphical representation, compared to the others - is the Ward\'s. This study is promising in the analysis of validity of clusters formed in vegetation data.
Farahi, Si Mohamed. "Etude phytochimique d'apiacées : selinum broteri, eryngium giganteum, ammi huntii, opopanax chironium." Mulhouse, 2001. http://www.theses.fr/2001MULH0656.
Full textWimmer, Johannes [Verfasser]. "Evaluierung von Knorpelersatzverfahren (AMIC und MACT) mittels optimierter Magnetresonanztomographie / Johannes Wimmer." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2011. http://d-nb.info/1015757650/34.
Full textSouza, Heraldo Namorato de. "Análise AMMI e SREG da interação genótipos x ambientes em milho." Universidade Federal de Viçosa, 2004. http://www.locus.ufv.br/handle/123456789/10485.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico
A avaliação de cultivares e a identificação de mega-ambientes são os objetivos mais importantes em ensaios de avaliação de cultivares. Com este propósito foram avaliados, nas safras 1998/1999 e 1999/2000, os dados de produtividade de milho precoce do Ensaio Nacional no Estado de Minas Gerais, objetivando não apenas o conhecimento do desempenho dos cultivares comerciais e pré-comerciais, mas, principalmente, avaliar por meio da comparação das metodologias multivariadas AMMI (Additive Main Effects and Multiplicative Interaction) e SREG (Sites Regression) de análise de interação genótipos x ambientes. Estas metodologias também possuem propriedades de estratificação de ambientes e de avaliação de adaptabilidade. Realizou-se comparação com outras metodologias tradicionais e com metodologia multivariada recém-proposta por Murakami (2001), com base na análise de fatores. O desempenho dos cultivares foi analisado mediante a utilização de análises de variância, metodologias de adaptabilidade e estabilidade. As análises AMMI e SREG apresentaram como vantagens o fato de explicarem uma maior parcela das soma de quadrados da interação G x A e possibilitar uma fácil interpretação gráfica dos resultados da análise estatística. Apesar de possuírem propriedades metodológicas de análise semelhantes, os resultados diferiram, na maioria das vezes, entre as análises AMMI e SREG. A análise SREG por incorporar o efeito de genótipo e por este na maioria dos casos estar altamente correlacionado com os escores do primeiro componente principal, possui a vantagem de permitir a avaliação gráfica direta do efeito de genótipo. O desenho de setores no biplot apresentado por Yan et al. (2000) e a análise SREG identificam com melhor propriedade a existência de mega-ambientes graficamente, prestando-se ao zoneamento agronômico. Como limitações das análises AMMI e SREG podem-se citar o requisito de dados balanceados, a explicação de apenas uma pequena porção da total da soma de quadrados G ou G + G x A, respectivamente, e a perda da medida de incerteza, pois não permitem o cálculo de uma hipótese em particular. A metodologia para estratificação de ambientes com base na técnica multivariada de análise de fatores mostrou-se eficiente em reunir locais pela similaridade de desempenho dos cultivares. Os agrupamentos de ambientes formados pela estratificação ambiental e a capacidade de discriminação de genótipos foram em parte coincidentes pelas metodologias utilizadas na avaliação dos dados. Dadas as condições de realização dos ensaios, alguns cultivares se destacaram por sua produtividade média, por seus resultados nas análises de estabilidade e pela adaptabilidade. Na safra 1998/1999, os genótipos P 30F33 e P 3041 se notabilizaram pelas suas produtividades e estabilidade através dos ambientes de avaliação. Na safra 1999/2000, o destaque foi o genótipo 98 HS 16B. Os ambientes Patos de Minas 2 e Uberlândia 2 de destacaram pela coincidência no agrupamento pela unanimidade das metodologias utilizadas, levando a inferir o forte caráter de homogeneidade edafoclimática pela proximidade geográfica, altitudes semelhantes e de localização nos Cerrados. Também a homogeneidade de manejo agrícola, praticada para estes dois ambientes, teve importância. As análises AMMI e SREG apresentaram propriedades importantes e adequadas ao estudo da interação genótipo x ambientes, sendo recomendadas suas utilizações pelos melhoristas de plantas.
The evaluation and identification of mega-environments are the major objectives in cultivar evaluation trials. Thus, the Minas Gerais National Trials data on early maize productivity were evaluated during 1998/1999 and 1999/2000, aiming not only to understand the performance of commercial and pre-commercial cultivars but especially to evaluate them by comparing the multivariate AMMI methodologies (Additive Main Effects and Multiplicative Interaction) and SREG (Sites Regression) of genotype x environments interaction analysis. Such methodologies also have environment stratification and adaptability evaluation properties. Comparison was made to other traditional methodologies and to the multivariate methodology recently proposed by Murakami (2001), based on factor analysis.Cultivar performance was analyzed by using variance analyses, and adaptability and stability methodologies. The AMMI and SREG analyses had the advantages of explaining a greater portion of the square sum of G x A interaction and allowing an easy graphic interpretation of the statistical analysis results. Despite having similar analysis methodological properties, the AMMI and SREG analyses xresults differed most of the times; the latter for incorporating the genotype effect and since, in most cases, it is highly correlated with the scores of the principal first component, having the advantages of allowing the direct graphic evaluation of the genotype effect. The sector design in the biplot presented by Yan et al. (2000) and the SREG analysis could better identify the existence of mega- environments graphically, being suitable for agronomical zoning. The AMMI and SREG analyses presented the following disadvantages: the requirement of balanced data, the explanation of only a small portion of the total sum of the squares G or G + G x A, respectively, and loss of uncertainty measurement, since it did not allow the calculation of a hypothesis in particular. The methodology applied for environment stratification based on factor analysis multivariate technique was found to be efficient in grouping locations based on cultivar performance similarity. The environment groupings formed by environmental stratification and genotype discrimination capacity coincided in part with the methodologies applied to data evaluation. Given the assay performance conditions, some cultivars stood out for their average productivity and stability and adaptability analysis results.In the 1998/1999 harvests, the genotypes P 30F33 and P 3041 presented outstanding productivities and stability in the evaluated environments. In the1999/2000 harvest, the genotype 98 HS 16B was the most outstanding. The environments Patos de Minas 2 and Uberlândia 2 stood out for coinciding in the grouping for unanimous methodology application, leading to infer the strong character of edaphoclimatic homogeneity due to geographic proximity, similar altitudes and locations in the cerrados. Homogeneity of the agricultural management practiced in these two environments was also important. The AMMI and SREG analyses presented important properties adequate to the study of genotype x environment interaction, their application being thus recommended by plant breeders.
Winn, Kerry Lynn. "Gunsmoke: An investigation of conversational implicature and Guns & Ammo magazine." CSUSB ScholarWorks, 2002. https://scholarworks.lib.csusb.edu/etd-project/2069.
Full textAndrade, Leonardo Neves de. "Estudo fenotípico e molecular de beta-lactamases de espectro estendido e AmpC em enterobactérias isoladas de pacientes com suspeita de meningite." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/60/60135/tde-02102008-163953/.
Full textMembers of Enterobacteriaceae family are cause of cause meningitis associated with nosocomial or secondary infection. The empiric therapy used in patients with suspicion of meningitis is, sometimes, inefficient due to extended-spectrum beta-lactamases (ESBL)- producing, that is the most common mechanism of resistance to cephalosporins in enterobacteria. The main objective of this study was to evaluate ESBL and AmpC-producing Enterobacteriaceae isolated of cerebrospinal fluid and blood from patients with suspicion of meningitis from the region of Ribeirão Preto city, during 2000 to 2005. Combination disk method was used for phenotypic detection and PCR was used to amplify genes encoding ESBL and AmpC. Three (6.52 %) out of 46 enterobacteria isolated in the period studied were detected as ESBL-producing and harbored the blaCTX-M-2 gene. The ESBL-producing enterobacteria were: S. marcescens IAL 19, (isolated in Araraquara city SP - Brazil, 2002), P. mirabilis IAL 29 e E. coli IAL 45 (isolated in Franca city SP- Brazil, respectively, 2003 e 2004). The blaCTX-M-2 gene was detected in three different genera isolated for a long time, suggesting that the blaCTX-M-2 gene is endemic in the region of Ribeirão Preto city. The data generated by this study are important because there are low reports about ESBL-producing enterobacteria isolated of cerebrospinal fluid and blood from patients with suspicion of meningitis.
HENNE, PATRICIA. "Interet du dosage de l'amp cyclique urinaire en peroperatoire lors d'hyperparathyroidie primaire." Strasbourg 1, 1989. http://www.theses.fr/1989STR15075.
Full textAl-Janabi, Muayad Sadik Croock. "Resource allocation software algorithms for AMC-OFDM systems." Thesis, University of Newcastle Upon Tyne, 2012. http://hdl.handle.net/10443/1537.
Full textWeeks, Colin. "Pulsed-flow microreactor studies of propene (Amm)oxidation." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266799.
Full textEkdahl, Cecilia, and Katarina Hallén. "Mödrars erfarenheter av att amma sina för tidigt födda barn efter hemkomst." Thesis, Linköpings universitet, Avdelningen för omvårdnad, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-98434.
Full textHaj, Slimane Ammar Zeineb. "Dynamique Spatiotemporelle de la protéine kinase AMPc dépendante dans les myocytes cardiaques." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00954406.
Full textAmma, Christoph [Verfasser], and T. [Akademischer Betreuer] Schultz. "Modellierung und Erkennung dreidimensionaler Handschrift mittels Inertialsensorik / Christoph Amma. Betreuer: T. Schultz." Karlsruhe : KIT-Bibliothek, 2015. http://d-nb.info/1106330161/34.
Full textLundström, Sofia, and Catarina Ivarsson. ""Kvinnor kan amma, män kan inte" : Mäns erfarenhet och upplevelse av amning." Thesis, Umeå universitet, Institutionen för omvårdnad, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-130159.
Full textPiovesan, Pamela. "Validação cruzada com correção de autovalores e regressão isotônica nos modelos AMMI." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-16102007-113618/.
Full textThis paper presents the application of AMMI models for a thorough study about the effect of the interaction between genotypes and environments in multi-environments experiments. Through the decomposition of the sum of squares of these interactions, one searches to select the number of terms that explains this interaction, discarding its noise in. There are two ways for choosing these terms: cross-validation and hypotheses test. The focus will be on the crossvalidation for its advantage of being one prediction criterion of evaluation. Two methods of cross-validation are presented , both outlined by Eastment and Krzanowski (1982) and Gabriel (2002). These methods use the decomposition by singular values in order to obtain eigenvalues referred to the matrix of interactions, whose sum of squares accurately gives us the sum of squares of the interation. As these eigenvalues either over- or underestimated (ARAÚJO; DIAS, 2002), these techniques of validation will be improved through the correction of these eigenvalues and, in order to rearrange them, isotonic regression will be used . A comparative study between these methods through real data will be carried out.
Carlsson, Malin, and Jessica Sundberg. "Prematuritet och amning : en litteraturöversikt över upplevelsen att amma det prematura barnet." Thesis, Sophiahemmet Högskola, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-2855.
Full textJohansson, Lisa. "Mammors upplevelser av att amma sitt prematurfödda barn på neonatalavdelning - En litteraturstudie." Thesis, Örebro universitet, Institutionen för hälsovetenskaper, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-84182.
Full textLafon, Anne. "Signalisation AMPc/PKA : rôle dans le développement du champignon filamenteux Aspergillus nidulans." Paris 7, 2005. http://www.theses.fr/2005PA077103.
Full textHongyu, Kuang. "Comparação do GGE biplot-ponderado e AMMI- ponderado com outros modelos de interação genótipo x ambiente." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/11/11134/tde-04052015-172304/.
Full textGenotype × environment interaction (GEI) is an extremely important issue in plant breeding and production. The selection and recommendation of superior genotypes are hampered due to the occurrence of GEI and represents a major challenge for researchers. In this context, biplot analyzes have been increasingly used in analyzing agronomic data, in which data are represented by a table of two entries of means of GEI. However, the particularities in the biplot graphic hamper its interpretation, and could lead the researcher to errors. There are several models in the literature for DGE analysis (GEI data), among them, the most used are the AMMI model (Additive Main effects and Multiplicative Interaction Models) and GGE biplot (Genotype main effects + Genotype environment interaction). The AMMI model is a statistical method to understand the structure of interactions between genotypes and environments, combining the analysis of variance and principal component analysis, to adjust, respectively, the main effects (G and E) and the effects of GEI. The GGE Biplot groups genotype of additive effect with multiplicative effect of GEI, and submit these to the principal component analysis. There are two problems in using these models: i) can only be used to analyze MET data (multi-environments), which has a unique feature and ii) whose environments are heterogeneous. This paper aims to propose new W-GGE biplot models (Weighted Genotype main efffects + Genotype environment interaction) and AMMI-weighted multi-environments for data analysis, and make a comparison between the existing models as AMMI and GGE biplot; mega-environment analysis; genotype evaluation, test environment within each mega-environment and understand the causes of GEI.
Rocha, Darlan Augusto da Costa. "Caracterização fenotípica e genotípica de betalactamases do tipo AmpC plasmidial em Escherichia coli." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-26062014-145930/.
Full textIntroduction: AmpC enzymes can degrade cephalosporins and cephamycins and are not inhibited by clavulanic acid, sulbactam or tazobactam. They can be encoded by genes of plasmid or chromosomal location. Detecting these enzymes is epidemiologically important because their expression and concomitant porins loss in Enterobacteriaceae can lead to resistance to carbapenems, antimicrobials widely used to treat serious infections. Reports of detection of plasmidial AmpCs in Brazil are scarce, but the analysis of the susceptibility profile of Escherichia coli isolated from cases of urinary tract infection in patients attended in a private laboratory, located at the city of São Paulo, from 2006 to 2010 indicated a considerable increase in cefoxitin resistance, a marker for plasmidial AmpC expression. In 2006 the rate was 0.03% and in 2011 it was 0.65%. One hypothesis for this increase was the spread of clones or genes encoding AmpC transferred into plasmids. Objective: To characterize the genetic determinants in E. coli presenting a phenotype consistent with plasmidial AmpC production. Material and Methods: We studied all E. coli not susceptible to cefoxitin isolated in urine cultures at Fleury Medicine and Health, in São Paulo, during the period from January 2nd to February 1st 2012. The isolates were phenotypically evaluated for purity, species identification and enzymatic blockage with cefoxitin and ceftazidime disks with added phenylboronic acid. The presence of genes encoding plasmidial AmpCs was evaluated using two different PCR methods. Sequencing of the genes detected was obtained. The performance of the enzymatic blockage with phenylboronic acid was determined using PCR as a gold standard. The plasmid profile and clonality were evaluated respectively by alkaline lysis and ERIC-PCR. Results and conclusions: Among 2,494 E. coli isolates, 12 had genes encoding for plasmidial AmpC; consequently the frequency of plasmidial AmpC in E. coli was 1.8% in inpatients and 0.46% in outpatients. Sequencing of the genes encoding plasmidial AmpCs showed them to be blaCMY-2 and just one blaCMY-4. The better performance of the phenotypic test was obtained when at least 5 mm inhibition zone difference was observed between the disc of cefoxitin and ceftazidime with added phenylboronic acid. With these parameters the sensitivity was 100%, specificity 100%, positive predictive value 100% and negative predictive value 100%. The presence and the dissemination of three clonal groups of CMY producing E. coli was observed among hospitals located at the city of São Paulo
Barbosa, Larissa Ferreira Regis. "AMC : afecção mediada por computador em coletivos performáticos desterritorializados." reponame:Repositório Institucional da UnB, 2010. http://repositorio.unb.br/handle/10482/7356.
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O presente trabalho aborda a constituição dos coletivos performáticos na performação em telepresença. Estes agrupamentos se encontram na simultaneidade dos tempos e forjam um espaço de afecção telemática. Na efemeridade dos gestos mediados, corpos de muitos se integram como grupo, o qual chamamos de coletivos performáticos desterritorializados. Estes são experienciados em iniciativas brasileiras que foram mapeadas nesta pesquisa: Açúcar Invertido, Antonieta Chegou Hoje, Corpos Informáticos, Grupo ERRO, Performídia, Perforum, Phila 7, Poética Tecnológica na Dança, Quik Corpo Aberto. A partir da análise desta cartografia itinerante, contrastamos a AMC (Afecção Mediada por Computador) com a CMC (Comunicação Mediada por Computador) a fim de distinguir os coletivos desterritorializados e as comunidades virtuais. Enfatizamos a AMC em sua urgência em fazer compartilhar, poeticamente e politicamente em intervenções que deflagram os espaços de poder na rede. As impressões resultam neste documento-inventivo que segue por planos de composição estética ao criar os seguintes conceitos: performação, ato-ação, corpo em obra, perfornomadismo, telepresença em circuito fechado e aberto, olhar incorporado, espaço em corpo. Agrupamos-nos, sobretudo, com Spinoza, Deleuze, Negri, Guattari, Certeau, Baudrillard. _________________________________________________________________________________ ABSTRACT
The presente research discursses accost the formation of collectives in the action of performance in telepresence. These groups find in the simultaneity of the time and found an affection telematics space. In ephemeral gestures mediated, bodies join as a group, which we call collective perfomartic deterritorialized. These are experienced in Brazilian initiatives that have been mapped in this research: Açúcar Invertido, Antonieta Chegou Hoje, Corpos Informáticos, Grupo ERRO, Performídia, Perforum, Phila 7, Poética Tecnológica na Dança, Quik Corpo Aberto. Based on the analysis of this map itinerant, constrasted AMC (Affection Mediated by Computer) with the CMC (Communication Computer mediated) in order to distinguish the collective deterritorialized and virtual communities. We emphasize the AMC in his urge to share, poetically and politically interverntions that trigger the spaces of power in the net. We made some impressions that result in this document-inventive about the performação, act-action, body in art, perfornomadismo, telepresence in closed circuit and open circuit, corporate eyes, space in body. We join with Spinoza, Deleuze, Negri, Guattari, Certeau, Baudrillard.