Relevant bibliographies by topics / Alternating Therapy

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Alternating Therapy'

Author: Grafiati
Published: 25 June 2021
Last updated: 4 February 2022

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Journal articles on the topic "Alternating Therapy"

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&NA;. "Alternating antiretroviral therapy prolongs viral suppression." Inpharma Weekly &NA;, no. 1476 (February 2005): 17. http://dx.doi.org/10.2165/00128413-200514760-00043.

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Hudis, Clifford. "Is There an Alternative to Alternating Adjuvant Therapy for Breast Cancer?" Cancer Investigation 12, no. 3 (January 1994): 329–35. http://dx.doi.org/10.3109/07357909409023032.

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Kassubek, J., O. Witzke, E. Bonmann, and E. Musch. "Alternating Immune Therapy in Renal Cell Carcinoma." Oncology Research and Treatment 18, no. 3 (1995): 252–54. http://dx.doi.org/10.1159/000218593.

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Kasinathan, Ananthanarayanan, Indar Kumar Sharawat, Jitendra Kumar Sahu, and Naveen Sankhyan. "Topiramate Therapy in Alternating Hemiplegia of Childhood." Indian Journal of Pediatrics 84, no. 12 (May 13, 2017): 957–58. http://dx.doi.org/10.1007/s12098-017-2366-5.

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Tian, Jia, Lei Xia, Jian Wu, Baoxuan Huang, Hongliang Cao, and Weian Zhang. "Linear Alternating Supramolecular Photosensitizer for Enhanced Photodynamic Therapy." ACS Applied Materials & Interfaces 12, no. 29 (June 25, 2020): 32352–59. http://dx.doi.org/10.1021/acsami.0c07333.

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Pandit, Sandeep V. "Alternating current for defibrillation therapy: Time for reconsideration?" Heart Rhythm 10, no. 5 (May 2013): 749–50. http://dx.doi.org/10.1016/j.hrthm.2013.01.031.

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Dibartolomeo, Joseph R., and Robert D. Yee. "Periodic Alternating Nystagmus." Otolaryngology–Head and Neck Surgery 99, no. 6 (December 1988): 552–57. http://dx.doi.org/10.1177/019459988809900603.

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Horizontal jerk nystagmus is indicative of a disorder involving the vestibular system. Periodic alternating nystagmus is a form of spontaneous nystagmus with a specific pattern. It is identified by the presence of spontaneous nystagmus in the primary direction of gaze, which beats in one direction for 1 or 2 minutes, followed by a null period, and then reappearance of the nystagmus in the opposite direction for a similar length of time. It may be congenital or acquired, and may be seen in association with vestibular-cerebellar disease or loss of vision. Recent case reports indicate that some forms of periodic alternating nystagmus may respond favorably to baclofen therapy.
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Ward, Alex R. "Electrical Stimulation Using Kilohertz-Frequency Alternating Current." Physical Therapy 89, no. 2 (February 1, 2009): 181–90. http://dx.doi.org/10.2522/ptj.20080060.

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Transcutaneous electrical stimulation using kilohertz-frequency alternating current (AC) became popular in the 1950s with the introduction of “interferential currents,” promoted as a means of producing depth-efficient stimulation of nerve and muscle. Later, “Russian current” was adopted as a means of muscle strengthening. This article reviews some clinically relevant, laboratory-based studies that offer an insight into the mechanism of action of kilohertz-frequency AC. It provides some answers to the question: “What are the optimal stimulus parameters for eliciting forceful, yet comfortable, electrically induced muscle contractions?” It is concluded that the stimulation parameters commonly used clinically (Russian and interferential currents) are suboptimal for achieving their stated goals and that greater benefit would be obtained using short-duration (2–4 millisecond), rectangular bursts of kilohertz-frequency AC with a frequency chosen to maximize the desired outcome.
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Hedrick, Allen. "The Split Alternating Foot Snatch." Strength and Conditioning Journal 38, no. 6 (December 2016): 76–80. http://dx.doi.org/10.1519/ssc.0000000000000231.

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Grimm, Jimm, Joseph Moore, Ted Hooker, Rachel Grimm, Ellen Huang, Juan Jackson, Kristin Redmond, and Lawrence Kleinberg. "RTHP-20. RADIATION THERAPY TARGETING ACCURACY WHEN COMBINED WITH ALTERNATING ELECTRIC FIELD THERAPY." Neuro-Oncology 19, suppl_6 (November 2017): vi223. http://dx.doi.org/10.1093/neuonc/nox168.904.

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Dissertations / Theses on the topic "Alternating Therapy"

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Sheehy, Suzanne Lyn. "Design of a non-scaling fixed field alternating gradient accelerator for charged particle therapy." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:d9cd977c-35db-45cc-ad33-67710fc3e82f.

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This thesis describes the design a novel type of particle accelerator for charged particle therapy. The accelerator is called a non-scaling, Fixed Field Alternating Gradient (ns-FFAG) accelerator, and will accelerate both protons and carbon ions to energies required for clinical use. The work is undertaken as part of the PAMELA project. An existing design for a ns-FFAG is taken as a starting point and analysed in terms of its ability to suit the charged particle therapy application. It is found that this design is particularly sensitive to alignment errors and would be unable to accelerate protons and carbon ions at the proposed acceleration rate due to betatron resonance crossing phenomena. To overcome this issue, a new type of non-linear ns-FFAG is developed which avoids resonance crossing and meets the requirements provided by clinical considerations. Two accelerating rings are required, one for protons up to 250 MeV and fully stripped carbon ions to 68 MeV/u, the other to accelerate the carbon ions up to 400-430 MeV/u. Detailed studies are undertaken to show that this new type of accelerator is suitable for the application. An alignment accuracy of 50 micrometers will not have a detrimental effect on the beam and the dynamic aperture for most lattice configurations is found to be greater than 50 pi.mm.mrad normalised in both the horizontal and vertical plane. Verification of the simulation code used in the PAMELA lattice design is carried out using experimental results from EMMA, the world's first ns-FFAG for 10-20 MeV electrons built at Daresbury Laboratory, UK. Finally, it is shown that the described lattice can translate into realistic designs for the individual components of the accelerator. The integration of these components into the PAMELA facility is discussed.
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He, Wei. "Mathematical Modeling of Therapies for MCF7 Breast Cancer Cells." Diss., Virginia Tech, 2021. http://hdl.handle.net/10919/103967.

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Estrogen receptor (ER)-positive breast cancer is responsive to a number of targeted therapies used clinically. Unfortunately, the continuous application of any targeted therapy often results in resistance to the therapy. Our ultimate goal is to use mathematical modelling to optimize alternating therapies that not only decrease proliferation but also stave off resistance. Toward this end, we measured levels of key proteins and proliferation over a 7-day time course in ER-positive MCF7 breast cancer cells. Treatments included endocrine therapy, either estrogen deprivation, which mimics the effects of an aromatase inhibitor, or fulvestrant, an ER degrader. These data were used to calibrate a mathematical model based on key interactions between ER signaling and the cell cycle. We show that the calibrated model is capable of predicting the combination treatment of fulvestrant and estrogen deprivation. Further, we show that we can add a new drug, palbociclib, to the model by measuring only two key proteins, c-Myc and hyperphosphorylated RB1, and adjusting only parameters associated with the drug. The model is then able to predict the combination treatment of estrogen deprivation and palbociclib. Then we added the dynamics of estrogen concentration in the medium into the model and extended the short-term model to a long-term model. The long-term model can simulate various mono- or combination treatments at different doses over 28 days. In addition to palbociclib, we add another Cdk4/6 inhibitor to the model, abemaciclib, which can induce apoptosis at high concentrations. Then the model can match the effects of abemaciclib treatment at two different doses and also capture the apoptosis effects induced by abemaciclib. After calibrating the model to these different treatment conditions, we used the model to explore the synergism among these different treatments. The mathematical model predicts a significant synergism between palbociclib or abemaciclib in combination with fulvestrant. And the predicted synergisms are verified by experiments. This critical synergism between these Cdk4/6 inhibitors and endocrine therapy could reflect the reason that Cdk4/6 inhibitors achieve pronounced success in clinic trails. Lastly, we used protein biomarkers (cyclinD1, cyclinE1, Cdk4, Cdk6 and Cdk2) and palbociclib dose-response proliferation assays to assess the difference between mono- and alternating therapy after 10 weeks of treatments. But neither the protein levels nor palbociclib dose-response show significant differences after 10 weeks of treatment. Therefore, we cannot conclude that alternating therapy delays palbociclib resistance compared with palbociclib mono-treatment after 10 weeks. Longer term experiments or other methods will be needed to uncover any difference. However, in this research we showed that a mechanism-based mathematical model is able to simulate and predict various effects of clinically-used treatments on ER-positive breast cancer cells at different time scales. And this mathematical model has the potential to explore ideas for potential drug treatments, optimize protocols that limit proliferation, and determine the drugs, doses, and alternating schedule for long term experiments.
Doctor of Philosophy
Estrogen receptors are proteins found inside breast cancer cells that are activated by the hormone estrogen. Estrogen-receptor positive breast cancer is the most common type of breast cancer and accounts for about 70% of breast cancer tumors. Endocrine therapy, which inhibits estrogen receptor signaling, and Cyclin-dependent kinase 4 and 6 (Cdk4/6) inhibitors are the preferred first-line therapy for patients with estrogen receptor-positive cancers. We built a mathematical model of MCF7 cells (an estrogen receptor-positive breast cancer cell line) in response to these standard first-line therapies. This mathematical model can capture the experimentally observed protein and cell proliferation changes in response to various treatment conditions, including different drug combinations, different doses, and different treatment durations up to 28 days. The model can then be used to look for more effective treatment possibilities. In particular, our mathematical model predicted a strong synergism between Cdk4/6 inhibitors and endocrine therapy, which could allow significant reductions in drug dosage while producing the same effect. This synergism was verified by experiments. In addition to treatment methods where one drug or combination of several drugs is used continuously, we consider alternating among various therapies in a fixed cycle. The mathematical model can help us determine which drugs and which doses might be most appropriate. Since an alternating therapy doesn't inhibit one particular target non-stop, the hope is that alternating therapies can delay the onset of drug resistance, where the drug becomes less effective or stops working completely. Unfortunately, an initial 10- week experiment to test for differences in resistance to a mono-therapy versus an alternating therapy did not show a significant difference, pointing to the need for longer experiments to see if alternating therapies can actually make a difference in resistance. Mathematical models will be important for determining the drugs, doses, and time intervals to be used in these experiments, as figuring out the best options by trial and error in such long-term experiments is not practical.
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Boyer, Valerie E. "Animal-assisted therapy in speech-language pathology : using an alternating treatment design to compare the effects of using animal-assisted therapy in working with children with language impairments /." Available to subscribers only, 2006. http://proquest.umi.com/pqdweb?did=1216741901&sid=4&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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Thesis (Ph.D.)--Southern Illinois University Carbondale, 2006.
"Department of Educational Psychology and Special Education." Includes bibliographical references (leaves 114-118). Also available online.
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Amano, Tamaki. "The role of alternating bilateral stimulation in establishing positive cognition in EMDR therapy: a multi-channel near-infrared spectroscopy study." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225519.

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Schmulian, Dunay Liezel. "The development of a universal speech facilitation program as an extension of the speech motor learning program and its application in an experimental alternating treatment study." Pretoria : [s.n.], 2000. http://upetd.up.ac.za/thesis/available/etd-07172006-130724.

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Parralego, Paula Alessandra Garcia Gripp. "Desenvolvimento e aplicação de um protocolo fisioterapêutico para lipodistrofia abdominal feminina por meio de técnicas eletrotermoterapêuticas." Universidade Tecnológica Federal do Paraná, 2015. http://repositorio.utfpr.edu.br/jspui/handle/1/1925.

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No Brasil 72% dos óbitos são decorrentes de complicações destas doenças. Associado ao alto custo do Sistema Público de Saúde e elevado risco às doenças secundárias, o excesso de peso, pode ocasionar a lipodistrofia localizada, esta, caracterizada pelas poucas alternativas de tratamento, sendo o tratamento cirúrgico o mais realizado. Poucos estudos demonstram a utilização de terapia auxiliar para a redução da lipodistrofia localizada e ainda há maior restrição em pesquisas específicas visando o tratamento da lipodistrofia abdominal. O presente estudo procurou verificar os efeitos de uma terapia não invasiva, em uma região específica predisponente ao acúmulo de gordura, o abdome. Foi realizado um estudo longitudinal, de abordagem quantitativa, do tipo descritiva, composto por 33 mulheres, com acúmulo de adiposidade abdominal, na faixa etária dos 20 a 35 anos. Inicialmente todas assinaram o Termo de Consentimento Livre e Esclarecido (TCLE); sequencialmente, houve uma divisão da amostra em dois grupos: A, que realizou dez sessões seguidas do protocolo fisioterapêutico e B, que realizou cinco sessões, seguida de uma pausa e realizou outras cinco sessões do protocolo. Todas as voluntárias responderam o questionário e realizaram a primeira avaliação corporal que foi repetida após a quinta e décima sessão do protocolo fisioterapêutico além da realização do exame de Densitometria por Absorciometria de Raios X de Dupla Energia (DXA) que foi realizado ao início e término das sessões, que consistiu na aplicação abdominal de um protocolo desenvolvido baseado em associação de duas técnicas fisioterapêuticas: o ultrassom de 3MHz e a corrente alternada de média frequência. Foram analisados inicialmente os dados coletados da amostra geral seguido da análise de comparação entre os grupos A e B, para a verificação da normalidade da distribuição utilizou-se o teste de Shapiro-Wilk e para a comparação dos dados utilizou-se a ANOVA de Friedman. Os resultados encontrados para as variáveis analisadas da amostra geral: massa, perimetria de cintura, perimetria de cicatriz umbilical, perimetria da menor circunferência abdominal, perimetria da maior circunferência abdominal e percentual de gordura de tronco avaliado por meio da DXA, apresentou o valor de p<0,001 verificando uma diferença significativa comparada à avaliação inicial à final. Em relação ao percentual de gordura corporal total avaliado pela DXA, o valor de “p” foi p=0,779, demonstrando uma redução com variação de 0,1% a 2,7% entre as voluntárias. Quando comparados os grupos A e B, observou-se homogeneidade entre os grupos e não foi apresentada diferença estatística entre eles, portanto não houve alteração do resultado final. Sendo assim, este protocolo foi desenvolvido especificamente para o tratamento da lipodistrofia abdominal feminina e durante o estudo se mostrou eficaz no tratamento para redução deste tipo de adiposidade em mulheres jovens.
In Brazil the complications of these illnesses are responsible for 72% of the deaths. Overweight combined with not only the high costs of health service provided by the government, but also with the high risk of secondary diseases, can cause localized lipodystrophy which has few alternatives for treatment, being surgical treatment the most common. Few studies show the usage of adjunctive therapy in order to reduce localized lipodystrophy and still they have greater restriction in specific research aiming at the treatment of localized abdominal lipodystrophy. The objective of this study was to verify the results of a non-invasive therapy in a specific area more predisposed to fat accumulation – the abdomen. A longitudinal study was performed, using a quantitative-descriptive research composed of 33 women with abdominal fat accumulation, with an age range of 20 to 35 years old. All of them signed an informed consent term (TCLE) and the sample was divided in two groups: A, which held ten physiotherapy sessions according to the physiotherapy protocol and B, which held five physiotherapy sessions, followed by a pause, and then held other five sessions according to the protocol. All the volunteers answered a questionnaire and went through their first body evaluation, which was repeated after the fifth and tenth session according to the physiotherapy protocol. They also underwent a Dual-Energy X-ray absorptiometry (DXA) test, repeated in the beginning and in the end of the sessions, which consisted of an application of a protocol, in the abdomen, developed based on the association of two physiotherapy techniques: 3-MHz ultrasound and medium-frequency alternating current. Initially, the general sample data was analyzed, followed by the comparative analysis between groups A and B. A Shapiro- Wilk test was performed to check the normality of the distribution and ANOVA Friedman was used to compare the data. The results for the variables analyzed in general sample were: mass, waist measurement, umbilical scar measurement, narrowest abdominal circumference measurement, widest abdominal circumference measurement and midsection fat percentage p<0,001, evaluated by DXA, showing a considerable difference if compared from the initial evaluation to the final. The percentage of total body fat evaluated by DXA was p=0,779 demonstrating reduction with a variation of 0,1% to 2,7% among all the volunteers. Comparing groups A and B, homogeneity could be observed and there was no statistic difference between them. Therefore, this protocol was developed specifically for the treatment of abdominal lipodystrophy in women and during the present study it demonstrated to be efficient for the treatment of reduction for this type of adiposity in young women.
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Müller, Pierrette A. "Autistic children and music therapy : the influence of maternal involvement in therapy." Thesis, University of Reading, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385078.

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Thurber, Shawn L. "The Effects of Direct Supervision on Therapist Behavior: A Functional Analysis." BYU ScholarsArchive, 2005. https://scholarsarchive.byu.edu/etd/298.

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Live (Direct) Supervision has always been key to training therapists. However, little research has been done to determine which type of direct supervision is most effective in changing therapist behavior. This study compared bug-in-the-ear (BITE), phone-in, and computer assisted (CA) supervision. The purpose of this study was to (a) complete functional analysis of each supervision type via an alternating feedback session, to determine each therapists' most effective form of supervision; (b) determine the effect of using the most-effective form of supervision on the therapists' adherence to treatment protocols during follow-up sessions; (c) determine the effect of therapist adherence on client in-session behaviors, and outcome assessments. Results of the functional analysis indicated that phone-in supervisory feedback was the least effective form of supervision. BITE and CA supervision were both found to be effective for at least one therapist. In follow-up sessions BITE supervision did not create sustained changes in overall adherence. CA feedback appeared to maintain overall therapist adherence. In affecting changes to client behavior and outcome scores BITE supervision gave mixed results. CA supervision created desired changes in client behaviors and outcome assessments. For practitioners in the field, this study demonstrates that client behavior does not improve without therapist intervention. Even when client behavior in session appears to be improving, marital distress may increase. This is especially true when therapist adherence does not improve. This study further demonstrates that when the therapists did not intervene appropriately the clients either worsened, or at best, stayed the same. When the therapists made even small improvements client behavior improved. Improving adherence to treatment protocols will always serve the best interest of the client.
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Zupancic, Christine Lyn. "Therapy or Culture: A Comparison of the Buckhorn Model of Therapy to Other Therapeutic Models in the United States." University of Cincinnati / OhioLINK, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=ucin974918319.

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Bates, Nora. "Alternative healing as a complement to traditional, western therapy." Online version, 2000. http://www.uwstout.edu/lib/thesis/2000/2000batesn.pdf.

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Books on the topic "Alternating Therapy"

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Wong, Eric T., ed. Alternating Electric Fields Therapy in Oncology. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9.

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Options: The alternative cancer therapy book. Garden City Park, N.Y: Avery Pub. Group, 1993.

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Oxenford, Rosalind. Reflexología: Técnicas sencillas para aliviar el estrés y estimular la mente. Barcelona: Parramón, 1998.

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Complementary & alternative medicine in breastfeeding therapy. Amarillo, TX: Hale Pub., 2011.

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Beyond psychoppression: A feminist alternative therapy. North Melbourne, Vic., Australia: Spinifex, 1995.

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Lawrence, Ronald Melvin. Magnet therapy: The pain cure alternative. Rocklin, CA: Prima Health, 1998.

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K, Gupta R. Epilepsy: Combination therapy by alternative medicine. 2nd ed. [Dehra Dun: Bishen Singh Mahendra Pal Singh, 2001.

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Music therapy for non-musicians. Batavia, Ohio: Dragonhawk Pub., 1997.

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Kasad, Kershasp N. Iscador therapy of cancer. Bombay: Progressive Writers Combine, 1990.

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Barbara, Allan. Guide to information sources in alternative therapy. Aldershot, Hants, England: Gower, 1988.

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Book chapters on the topic "Alternating Therapy"

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Gera, Nidhi, and Kenneth D. Swanson. "Cell Biological Effects of Tumor Treating Fields." In Alternating Electric Fields Therapy in Oncology, 1–14. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_1.

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Wong, Eric T., Minesh P. Mehta, Andrew A. Kanner, and Manmeet S. Ahluwalia. "Future Directions for Tumor Treating Fields." In Alternating Electric Fields Therapy in Oncology, 117–26. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_10.

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Lok, Edwin, and Erno Sajo. "Fundamental Physics of Tumor Treating Fields." In Alternating Electric Fields Therapy in Oncology, 15–27. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_2.

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Wenger, Cornelia, and Pedro C. Miranda. "Biophysical Effects of Tumor Treating Fields." In Alternating Electric Fields Therapy in Oncology, 29–39. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_3.

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Lok, Edwin, Eric T. Wong, and Erno Sajo. "Computer Simulation of Tumor Treating Fields." In Alternating Electric Fields Therapy in Oncology, 41–54. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_4.

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Vymazal, Josef, Aaron M. Rulseh, and Eric T. Wong. "Response Pattern and Modeling of Tumor Treating Fields." In Alternating Electric Fields Therapy in Oncology, 55–65. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_5.

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Wong, Eric T. "Clinical Efficacy of Tumor Treating Fields for Recurrent Glioblastoma." In Alternating Electric Fields Therapy in Oncology, 67–77. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_6.

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Ruzevick, Jacob, Eric T. Wong, and Maciej M. Mrugala. "Tumor Treating Fields in Clinical Practice with Emphasis on PRiDe Registry." In Alternating Electric Fields Therapy in Oncology, 79–92. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_7.

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Wong, Eric T., and Zvi Ram. "Tumor Treating Fields Therapy for Newly Diagnosed Glioblastoma." In Alternating Electric Fields Therapy in Oncology, 93–102. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_8.

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Lacouture, Mario E., John DeNigris, and Andrew A. Kanner. "Supportive Care in Patients Using Tumor Treating Fields Therapy." In Alternating Electric Fields Therapy in Oncology, 103–16. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30576-9_9.

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Conference papers on the topic "Alternating Therapy"

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Van de Kerkhove, C., M. Kicinski, P. C. Goeminne, T. S. Nawrot, and L. J. Dupont. "Alternating inhaled antibiotic therapy in CF: A single center analysis." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa1295.

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Liu, Xiaoguang, Jie Li, Timon Chengyi Liu, Jianqin Yuan, and Qingming Luo. "Randomized trial comparing exercise therapy, alternating cold and hot therapy, and low intensity laser therapy for chronic lumbar muscle strain." In Photonics and Optoelectronics Meetings, edited by Qingming Luo, Lihong V. Wang, and Valery V. Tuchin. SPIE, 2008. http://dx.doi.org/10.1117/12.823363.

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Bai, Jingfeng, Xiaogang Fu, and Yazhu Chen. "Power controlling strategy for cryosurgery & RF alternating thermal therapy system." In 2008 International Conference on Technology and Applications in Biomedicine (ITAB). IEEE, 2008. http://dx.doi.org/10.1109/itab.2008.4570614.

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Feng, Xiaohua, Fei Gao, and Yuanjin Zheng. "A self-monitored theranostic platform based on nanoparticle hyperthermia therapy and alternating magnetic field induced thermoacoustic imaging." In SPIE BiOS, edited by Alexander A. Oraevsky and Lihong V. Wang. SPIE, 2015. http://dx.doi.org/10.1117/12.2078612.

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Stigliano, Robert V., Fridon Shubitidze, and P. Jack Hoopes. "Magnetic Nanoparticle Hyperthermia Cancer Therapy Temperature Distribution Modeling and Validation." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93123.

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The use of magnetic nanoparticles (mNP’s) in hyperthermia therapy for the treatment of cancer has been receiving increasing interest in the past few decades. It is known that heating cancerous tissues to temperatures above physiologically normal levels will cause cytotoxicity. In mNP hyperthermia, mNP’s are either injected intravenously or directly into the tumor site. In many tumor types the nanoparticles are invaginated into the cancer cells and aggregated into endosomes. Local temperature increases are achievable by exposing tumors containing mNP’s to an alternating magnetic field (AMF). The proximity of the mNP’s has a strong influence on their ability to generate heat due to inter-particle magnetic interaction effects [1, 2]. Taking this effect into account is important when modeling the heating characteristics of mNP’s.
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Thamire, Chandrasekhar, Rabee Zuberi, Charlie Choe, and Prabhakar Pandey. "Treatment Planning for Transurethral and Interstitial Thermal Therapy for Benign Prostatic Hyperplasia." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-10903.

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The purpose of this study is to develop thermal-damage correlations for transurethral and interstitial thermotherapy to aid treatment planning for benign prostatic hyperplasia (BPH). Using an Alternating-direction implicit method, the Pennes bioheat transfer equation is solved for microwave and ultrasound hyperthermia applicators for a range of parameters, including the applicator power, treatment time, and coolant parameters. Thermal coagulation contours are developed by evaluating the temperature-history data against the thermal-damage data obtained in ex-vivo experiments for prostate tissue slices and cells. Treatment protocols are proposed for treatment planning purposes and developing an optimal hyperthermia applicator that can coagulate the target tissue effectively, without destroying the surrounding healthy tissue.
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Voloshin, Tali, Noa Kaynan, Shiri Davidi, Yaara Porat, Anna Shteingauz, Mijal Munster, Rosa S. Schneiderman, et al. "Abstract 3961: Alternating electric fields (TTFields) induce immunogenic cell death resulting in enhanced antitumor efficacy when combined with anti-PD-1 therapy." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-3961.

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Voloshin, Tali, Noa Kaynan, Shiri Davidi, Yaara Porat, Anna Shteingauz, Mijal Munster, Rosa S. Schneiderman, et al. "Abstract 3961: Alternating electric fields (TTFields) induce immunogenic cell death resulting in enhanced antitumor efficacy when combined with anti-PD-1 therapy." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-3961.

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Thamire, Chandrasekhar, Rao L. Divi, and Mukesh Verma. "A Theoretical Comparison of the Efficacy of Microwave and Ultrasound Applicators Used in Transurethral Thermal Therapy." In ASME 2005 Summer Heat Transfer Conference collocated with the ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems. ASMEDC, 2005. http://dx.doi.org/10.1115/ht2005-72674.

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Microwave and ultrasound energy sources are commonly used in minimally invasive thermal therapy for benign prostatic hyperplasia. Successful management of the therapy using either of these methods requires an accurate estimation of the thermal dosage. The purpose of this study is to evaluate, theoretically, the thermal damage caused by typical transurethral microwave and ultrasound applicators for different thermal doses and compare the efficacy of the two methods. Using an Alternating-direction implicit method, the Pennes bio-heat transfer equation is solved for different levels of power and heating times. Internal and external cooling is applied to preserve the urethral and rectal lining and to control the temperatures within the tissue. The extent of thermal coagulation is determined from the resulting temperature histories, using the existing experimental thermal damage data for prostate tumor cells. The temperatures and damage contours calculated are validated using an Arrhenius analysis of the temperature and thermal-lesion data from the available experimental results. Results show that the calculated damage zones are in good agreement with those observed in the experiments. Results from calculations for different combinations of the parameters are presented in terms of the transient temperature histories and radial and axial extent of the lesion shapes. These results suggest that both methods can yield comparable thermal damage, though ultrasound appears to possess an improved control of directional heating.
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Jiang, Junfeng, Ruoyu Hong, Xiaohui Zhang, and Hongzhong Li. "On the in Vitro Hyperthermia of Magnetic Fluid in AC Magnetic Field." In ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer. ASMEDC, 2009. http://dx.doi.org/10.1115/mnhmt2009-18547.

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Hyperthermia therapy for cancer has attracted much attention nowadays. The study on the heat transfer in the magnetic fluid and the tumor is crucial for the successful application of magnetic fluid hyperthermia (MFH). Water-based Fe3O4 magnetic fluid is expected to be a most appropriate candidate for MFH due to the good biocompatibility, high saturation magnetization, super-paramagnetization and high chemical stability. In this paper, we explore the heat generation and transfer in magnetic fluid which is placed under an AC magnetic field. It is found that the amplitude and the frequency of alternating magnetic field, particle size and volume fraction have a pronounce influence on maximum temperature of hyperthermia.
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Reports on the topic "Alternating Therapy"

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Almeida, Sandra, Sandra G. Leichliter, Linda K. Hervig, Jackson Streeter, and Karen Maxwell-Williams. Low-Level Laser Therapy: A New Treatment Alternative Effective for Acute Exercise-Related Tendinitis. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada420506.

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Sun, Manqiang, Qi Chen, Tian Zhou, Dan Wang, Xueni Fang, Haoyue Pang, Yu Chen, et al. Efficacy and Safety of Complementary and Alternative Medicine Therapy for gastroparesis: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2020. http://dx.doi.org/10.37766/inplasy2020.10.0033.

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Chen, Min'an, Mingmin Zhu, Yimin Zhang, Sisi Zhao, Yu Guo, Luxi Cao, Hai Zeng, Zhuowen Lin, and Shiqi Wang. Can Acupuncture be a Complementary or Alternative Therapy for Ulcerative Colitis? A Systematic Review and Meta-Analysis of Randomized Controlled Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2021. http://dx.doi.org/10.37766/inplasy2021.9.0041.

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Lumpkin, Shamsie, Isaac Parrish, Austin Terrell, and Dwayne Accardo. Pain Control: Opioid vs. Nonopioid Analgesia During the Immediate Postoperative Period. University of Tennessee Health Science Center, July 2021. http://dx.doi.org/10.21007/con.dnp.2021.0008.

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Background Opioid analgesia has become the mainstay for acute pain management in the postoperative setting. However, the use of opioid medications comes with significant risks and side effects. Due to increasing numbers of prescriptions to those with chronic pain, opioid medications have become more expensive while becoming less effective due to the buildup of patient tolerance. The idea of opioid-free analgesic techniques has rarely been breached in many hospitals. Emerging research has shown that opioid-sparing approaches have resulted in lower reported pain scores across the board, as well as significant cost reductions to hospitals and insurance agencies. In addition to providing adequate pain relief, the predicted cost burden of an opioid-free or opioid-sparing approach is significantly less than traditional methods. Methods The following groups were considered in our inclusion criteria: those who speak the English language, all races and ethnicities, male or female, home medications, those who are at least 18 years of age and able to provide written informed consent, those undergoing inpatient or same-day surgical procedures. In addition, our scoping review includes the following exclusion criteria: those who are non-English speaking, those who are less than 18 years of age, those who are not undergoing surgical procedures while admitted, those who are unable to provide numeric pain score due to clinical status, those who are unable to provide written informed consent, and those who decline participation in the study. Data was extracted by one reviewer and verified by the remaining two group members. Extraction was divided as equally as possible among the 11 listed references. Discrepancies in data extraction were discussed between the article reviewer, project editor, and group leader. Results We identified nine primary sources addressing the use of ketamine as an alternative to opioid analgesia and post-operative pain control. Our findings indicate a positive correlation between perioperative ketamine administration and postoperative pain control. While this information provides insight on opioid-free analgesia, it also revealed the limited amount of research conducted in this area of practice. The strategies for several of the clinical trials limited ketamine administration to a small niche of patients. The included studies provided evidence for lower pain scores, reductions in opioid consumption, and better patient outcomes. Implications for Nursing Practice Based on the results of the studies’ randomized controlled trials and meta-analyses, the effects of ketamine are shown as an adequate analgesic alternative to opioids postoperatively. The cited resources showed that ketamine can be used as a sole agent, or combined effectively with reduced doses of opioids for multimodal therapy. There were noted limitations in some of the research articles. Not all of the cited studies were able to include definitive evidence of proper blinding techniques or randomization methods. Small sample sizes and the inclusion of specific patient populations identified within several of the studies can skew data in one direction or another; therefore, significant clinical results cannot be generalized to patient populations across the board.
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Tidd, Alexander N., Richard A. Ayers, Grant P. Course, and Guy R. Pasco. Scottish Inshore Fisheries Integrated Data System (SIFIDS): work package 6 final report development of a pilot relational data resource for the collation and interpretation of inshore fisheries data. Edited by Mark James and Hannah Ladd-Jones. Marine Alliance for Science and Technology for Scotland (MASTS), 2019. http://dx.doi.org/10.15664/10023.23452.

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[Extract from Executive Summary] The competition for space from competing sectors in the coastal waters of Scotland has never been greater and thus there is a growing a need for interactive seascape planning tools that encompass all marine activities. Similarly, the need to gather data to inform decision makers, especially in the fishing industry, has become essential to provide advice on the economic impact on fishing fleets both in terms of alternative conservation measures (e.g. effort limitations, temporal and spatial closures) as well as the overlap with other activities, thereby allowing stakeholders to derive a preferred option. The SIFIDS project was conceived to allow the different relevant data sources to be identified and to allow these data to be collated in one place, rather than as isolated data sets with multiple data owners. The online interactive tool developed as part of the project (Work Package 6) brought together relevant data sets and developed data storage facilities and a user interface to allow various types of user to view and interrogate the data. Some of these data sets were obtained as static layers which could sit as background data e.g. substrate type, UK fishing limits; whilst other data came directly from electronic monitoring systems developed as part of the SIFIDS project. The main non-static data source was Work Package 2, which was collecting data from a sample of volunteer inshore fishing vessels (<12m). This included data on location; time; vessel speed; count, time and position of deployment of strings of creels (or as fleets and pots as they are also known respectively); and a count of how many creels were hauled on these strings. The interactive online tool allowed all the above data to be collated in a specially designed database and displayed in near real time on the web-based application.
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Mindfulness therapy may provide an alternative to continuing antidepressants in preventing recurrence of depression. National Institute for Health Research, July 2015. http://dx.doi.org/10.3310/signal-000026.

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High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies. National Institute for Health Research, May 2016. http://dx.doi.org/10.3310/signal-000240.

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Heated, humidified high-flow oxygen therapy may be a useful alternative to other forms of respiratory support for preterm babies. National Institute for Health Research, December 2015. http://dx.doi.org/10.3310/signal-000159.

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