Academic literature on the topic 'Alternatifs'
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Journal articles on the topic "Alternatifs":
Stréliski, Jean-Jacques. "Courants alternatifs." Gestion 42, no. 2 (2017): 12. http://dx.doi.org/10.3917/riges.422.0012.
Deléage, Jean-Paul. "Écologistes et alternatifs." Ecologie & politique N°28, no. 1 (2004): 161. http://dx.doi.org/10.3917/ecopo.028.0161.
Poirier, Laetitia, Éric Ghigo, David Daudé, and Éric Chabrière. "Modèles alternatifs (6)." médecine/sciences 35, no. 6-7 (June 2019): 544–48. http://dx.doi.org/10.1051/medsci/2019110.
Moreau, Rémi. "LES MARCHÉS ALTERNATIFS." Assurances 67, no. 2 (1999): 215. http://dx.doi.org/10.7202/1105262ar.
Mitra, Goldis, Agnes Grudniewicz, M. Ruth Lavergne, Renee Fernandez, and Ian Scott. "Modes de rémunération alternatifs." Canadian Family Physician 67, no. 11 (November 2021): 812–15. http://dx.doi.org/10.46747/cfp.6711812.
Deléage, Estelle. "Les mouvements agricoles alternatifs." Informations sociales 164, no. 2 (2011): 44. http://dx.doi.org/10.3917/inso.164.0044.
Concialdi, Pierre, Frédéric Pierru, and Louis Weber. "Les indicateurs économiques alternatifs." Savoir/Agir 8, no. 2 (2009): 43. http://dx.doi.org/10.3917/sava.008.0043.
Ferron, Benjamin. "Professionnaliser les « médias alternatifs » ?" Savoir/Agir 38, no. 4 (2016): 21. http://dx.doi.org/10.3917/sava.038.0021.
Texier, Bruno. "Trois réseaux sociaux alternatifs." Archimag N°322, no. 2 (March 1, 2019): 52. http://dx.doi.org/10.3917/arma.322.0052.
Zuger, Abigail, and Nicolas Saintonge. "La magie des traitements alternatifs." Books N° 93, no. 12 (December 3, 2018): 82–83. http://dx.doi.org/10.3917/books.093.0082.
Dissertations / Theses on the topic "Alternatifs":
Tanaka, Iris. "Régulation de l'épissage et de la polyadénylation alternatifs par les agents anti-cancéreux génotoxiques." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS025/document.
Most human coding genes generate alternative transcripts (isoforms) through alternative splicing (AS) and alternative polyadenylation (APA), most often within the coding region and the 3’ untranslated region (3’UTR), respectively. Both AS and 3’UTR-APA regulations have been increasingly involved in oncogenesis. In particular, AS networks connecting oncogenic splicing factors and oncogenic splicing variants have been recently identified. AS is also widely regulated by genotoxic anticancer drugs, like doxorubicin and cisplatin that induce different types of DNA lesions and are widely used in breast cancer and non-small-cell lung cancer (NSCLC) therapy, respectively. Given the frequent occurrence of resistance to chemotherapy, understanding the underlying mechanisms is crucial to overcome this major issue. There are examples of AS events associated with anticancer drug resistance, but very little is known about the splicing factors and therefore the AS networks involved. In addition, a previous study showed that doxorubicin represses a large set of alternative last exons (ALE) corresponding to the use of intronic polyadenylation (IPA) sites. ALEs have an emerging role in cancer, but little is known about its regulation by other anticancer drugs, like cisplatin. In order to better understand the role of AS and APA regulation in cell response and resistance to chemotherapy, my PhD project had two main aims: 1) determine the extent, regulatory networks and function of AS regulation in breast cancer cell resistance to doxorubicin, and 2) determine the extent, mechanism and impact of ALE regulation in response to cisplatin in NSCLC cells. In the first part, I identified by RNA-seq thousands of AS events and dozens of splicing factors regulated in a cell model of acquired resistance to doxorubicin in ER+ breast cancer. Through an siRNA miniscreen, I found two splicing factors, ZRANB2 and SYF2, involved in doxorubicin resistance. Further RNA-seq analyses revealed the AS events regulated by depletion of these poorly characterized splicing factors, and their convergence on the alternative exon 5 of the oncogene ECT2. Depletion of ZRANB2, SYF2 and the ECT2-Ex5 variant reduces doxorubicin-induced S phase arrest and doxorubicin resistance. In addition, high inclusion levels of ECT2-Ex5 correlate with poor survival specifically in ER+ breast cancer treated with chemotherapy. In the second part, I found by 3’-seq that in NSCLC cell treatment with cisplatin (but not oxaliplatin) induces ALE/IPA in thousands of genes enriched in cell cycle and cell death. This effect is linked to an inhibition of transcription elongation processivity in long genes. 3’-seq analysis on polysomes showed that this ALE regulation impacts the translatome, and revealed a set of particularly short isoforms that were inefficiently translated, including a transcript with a non-coding function. In conclusion, during my thesis, I could identify a novel AS network involved in doxorubicin resistance in ER+ breast cancer, and widespread ALE regulation impacting the translatome in lung cancer cisplatin response. This work increases our understanding of AS and IPA role in cell response and resistance to anti-cancer chemotherapy. In the longer term, the identified alternative transcripts and regulators constitute candidate biomarkers of chemoresistance
Prache, Nolwenn. "Apport des solvants alternatifs pour la cartographie du lipidome par chromatographie." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS052/document.
Green analytical chemistry development represents one of the main issues of the 21th century. Many investigators in analytical chemistry are actually involved in the development of well-established analytical methods that prevent irreversible damage to humans and environment. In the domain of lipid analysis, structural diversity as well as difference in solubility of these compounds is leading to work with a very large polarity range to separate lipids by classes. The normal-phase liquid chromatography (NPLC) allows realising the elution of compounds in order of increasing polarity. The solubilisation of lipid classes requires the use of a mixture of several solvents, among them chloroform, n-heptane, dichloromethane. Moreover, organic solvents traditionally used in NPLC, although well performing are raising different problems due to their original source, i.e. fossil hydrocarbons, volatility and toxicity for humans and environment. One of the ways to avoid such solvents is the substitution with alternative solvents, as proposed by various players in green chemistry. The interest raised by these solvents, is promising in terms of reduction of solvent use with a significant environmental impact. The properties of supercritical fluid chromatography using CO₂ are similar to NPLC and also offer a green alternative to this method. This work has highlighted that separation methods could be developed with alternative solvents to n-heptane, methanol and chloroform. Their use is compatible with liquid and supercritical chromatography and offer better selectivity in terms of separation of lipid classes. The compatibility of alternative solvents with ELSD and mass spectrometry was also evaluated, which showed that the unavailability of sufficient purity could be an issue. However, this problem was also observed with the use of commercial solvents, which presented impurities such as fatty acids, polymers and antioxidants
Jorge, Manuel. "Les rattachements alternatifs en droit international privé." Paris 1, 1988. http://www.theses.fr/1988PA010294.
The complexity of the structure and the working of the alternative conflicts rules are used in this kind of rules with a teleological character. What is the significance of the connecting factors in the light of the competing substantive rules? They take into consideration the parties interests and pay greater attention to the social realities by providing that several designated laws apply alternatively. But the alternative conflicts rules cannot be considered as substantive rules. In fact, the "closest connection" principle can be used as a corrector of the alternatives conflicts rules
Xu, Xiao. "Généralisation d'automates alternatifs sur des alphabets infinis." Thesis, Université Grenoble Alpes, 2020. http://www.theses.fr/2020GRALM007.
The language inclusion problem is recognised as being central to verification in different domains, such as hardware, communication protocols, software systems, etc. There we might face two challenges: non-determinism and infinite alphabets.We propose two models of alternating automata over infinite alphabets: (i) alternating data automata (ADA) and (ii) first-order alternating data automata (FOADA). They both recognise the data words over infinite alphabets. In ADA model, the control states are Booleans and the transition rules are specified by a set of formulae in a combined first-order theory of states (Booleans) and data that relate past values of variables with current values of variables. But a restriction of the ADA model is that, there is not hidden variable, hence all the data values taken by the variables are visible in the input. But in FOADA model, the arguments of a predicate atom track the values of the internal variables associated with the state, and these values are invisible in the input sequence, which overcomes the restriction of the ADA model.With these two alternating models, Boolean operations of union, intersection and comple- ment can be done in linear time, thus matching the complexity of performing these opera- tions in the finite-alphabet case. However, the price to be paid here is that the emptiness checking becomes undecidable. For this reason, we provide two efficient semi-algorithms for emptiness checking: (i) lazy predicate abstraction and (ii) IMPACT method. These semi-algorithms are proven to terminate by returning a word from the language of the given au- tomaton if one exists; but if the language of the given automaton is empty, then the termination is not guaranteed.The main application of our models is checking inclusions between various classes of au- tomata extended with variables ranging over infinite domains that recognise languages over infinite alphabets. The most widely known classes of this kind are timed automata and finite- memory (register) automata. Another application is checking safety (mutual exclusion, absence of deadlocks, etc.) and liveness (termination, lack of starvation, etc.) properties of parameterised concurrent programs.Besides the theoretical parts, we also have developed a tool - FOADA Checker, mainly used for checking inclusion between two automata or checking emptiness of an automaton. FOADA Checker is written in Java, via Java-SMT interface and using Z3 SMT solver for spuriousness, coverage queries and interpolant generation. The IMPACT semi-algorithm has been implemented in the tool to check the emptiness of an automaton
Jorge, Manuel. "Les Rattachements alternatifs en droit international privé." Lille 3 : ANRT, 1989. http://catalogue.bnf.fr/ark:/12148/cb37614551t.
Emilian, Marine. "Aspects juridiques des modes alternatifs de règlement des différends en droit des affaires : une réelle alternative ?" Paris 10, 2001. http://www.theses.fr/2001PA100209.
The Alternative Dispute Resolution methods (R. A. D. ) are sources of a large curiosity actually. Their identity, characteristics, and processes must be clarified to have a better knowledge. These R. A. D. , very innovative, are not completely successful in France, or even in United States or Asia. In France and Asia, they are rarely used. In the Untied States, it exist some very imaginative methods but practically, they are very uncommon. On the other hand, it seems that the R. A. D. Are more adapted to the international context where their development and institutionalisation are increasing. The international context is effectively more convenient for the use of new methods which are flexible, non coercive, non binding and very far from governmental laws. The processes proposed can be used anywhere, without any legal barrier. Among these methods, we can note the mediation (judiciary and not judiciary) success in France and abroad. The mediation seems to be the helpful alternative to classic justice
Fathallah, Mourad. "Contribution à l'intégration d'algorithmes de commande des machines électriques à courant alternatif." Lyon, INSA, 2001. http://www.theses.fr/2001ISAL0051.
Vigneault, Karine. "Sujet des médias alternatifs: un citoyen néolibéral modèle?" Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18209.
Par-delà leur contenu, les médias alternatifs apparus au cours de la dernière décennie constituent aussi une pratique sociale concrète qui présuppose et, donc, contribue à normaliser une définition de la réalité donnée. Plus particulièrement, ces médias doivent faire appel à une conception du sujet politique déterminée afin de se présenter comme pratique rationnelle. À partir d’entrevues réalisées auprès de bénévoles de médias alternatifs du Québec, c’est cet idéal du sujet que nous avons cherché à caractériser. S’est ainsi vu dressé un portrait en trois temps : conçu sous l’angle (1) expressiviste, l’individu apparaît comme (2) « soi entreprise », mais un « soi entreprise » s’insérant dans des (3) communautés d’intérêts. Or, en s’articulant autour de cette définition du sujet politique plutôt qu’une autre, les médias alternatifs s’appuient sur une subjectivité très près de celle que présuppose une rationalité néolibérale de gouvernement à laquelle, pourtant, ils s’opposent ouvertement.
Sirichantranon, Wuttipong. "Les modes alternatifs de règlement des litiges fiscaux." Paris 2, 2010. http://www.theses.fr/2010PA020058.
Chadaigne, Pierre-José. "La communication alternative : la presse parallèle en France des années soixante à la fin des années quatre-vingt-dix." Paris 2, 2002. http://www.theses.fr/2002PA020009.
Books on the topic "Alternatifs":
1922-, Debuyst Frédéric, Wautelet Jean-Marie, Conseil pour le développement intégré., and Séminaire "Projets alternatifs et démocratie" (1985 : Université catholique de Louvain), eds. Projets alternatifs et démocratie. [Louvain-la-Neuve]: CIACO éditeur, 1987.
Esteban. Devenons des médi@s alternatifs: Guide des médias alternatifs et des sources d'informations différentes. Lyon, France: P'tit Gavroche, 2006.
Terroni, Cristelle. New York seventies: Avant-garde et espaces alternatifs. Rennes: Presses universitaires de Rennes, 2015.
Blakeman, Robyn. Strategic uses of alternative media: Just the essentials. Armonk, N.Y: M.E. Sharpe, 2011.
Hébert, Jean. Réflexion sur le maldéveloppement et les concepts alternatifs de développement. [Sainte-Foy]: Centre de recherches en aménagement, 1988.
Jean-Louis, Baudouin, Rouleau Gontran, Association Henri Capitant des amis de la culture juridique française., Barreau du Québec, and Chambre des notaires du Québec., eds. Médiation et modes alternatifs de règlement des conflits: Aspects nationaux et internationaux. Cowansville, Qué: Éditions Y. Blais, 1997.
Berry, Leonard. Systèmes alternatifs et durables de production et de subsistance pour les terres marginales. [S.l.]: Bureau des Nations Unies pour la région soudano-sahélienne, 1992.
magistrat, Chevalier Pierre, Desdevises Yvon, and Milburn Philip, eds. Les modes alternatifs de règlement des litiges: Les voies nouvelles d'une autre justice. Paris: Mission de recherche Droit et justice, 2003.
1951-, Böhler Karl, and Vereinigung Schweizerischer Archivare, eds. Scan or Mikrofilm: Ja, nein, beides?! =: Scanner ou microfilm: outils alternatifs ou complémentaires?! Zürich: ETH-Bibliothek, 2001.
Canadian Society of Civil Engineers., ed. Multiphasal alternating currents. [S.l: s.n., 1986.
Book chapters on the topic "Alternatifs":
Coffin, Benoî. "Syndrome de l’intestin irritable: traitements conventionnels et alternatifs." In Post’U FMC-HGE, 85–94. Paris: Springer Paris, 2011. http://dx.doi.org/10.1007/978-2-8178-0237-4_10.
Stewart, Paul. "Alternating and Alternative Sexualities." In Sex and Aesthetics in Samuel Beckett’s Work, 99–132. New York: Palgrave Macmillan US, 2011. http://dx.doi.org/10.1057/9780230339279_5.
Langen, Rainer. "Sind alternative Finanzierungen noch alternativ?" In Finanzierungschancen trotz Bankenkrise, 67–81. Wiesbaden: Springer Fachmedien Wiesbaden, 2015. http://dx.doi.org/10.1007/978-3-658-07772-3_7.
Moser, F., M. Naradoslawsky, and J. Schulte. "Alternative Research or Research on Alternatives?" In Ultra High Dilution, 255–61. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-015-8342-8_26.
Capdepuy, Vincent. "Les mots « alternatifs »." In Le Monde ou rien, 77–112. Presses universitaires de Lyon, 2023. http://dx.doi.org/10.4000/books.pul.52380.
"4 Solvants alternatifs." In Chimie verte, 277–338. EDP Sciences, 2020. http://dx.doi.org/10.1051/978-2-7598-2002-3-005.
"4 Solvants alternatifs." In Chimie verte, 277–338. EDP Sciences, 2020. http://dx.doi.org/10.1051/978-2-7598-2002-3.c005.
Deléage, Jean-Paul. "Écologistes et alternatifs." In Histoire des gauches en France, 146–58. La Découverte, 2005. http://dx.doi.org/10.3917/dec.becke.2005.02.0146.
"Indicateurs alternatifs du bien-être." In Réformes économiques, 133–48. OECD, 2006. http://dx.doi.org/10.1787/growth-2006-7-fr.
Pruvost, Geneviève. "Modes de vie alternatifs et engagement." In En quête d’alternatives, 218–24. La Découverte, 2017. http://dx.doi.org/10.3917/dec.badie.2017.01.0218.
Conference papers on the topic "Alternatifs":
ABRIAK, Nor Edine, Raouf ACHOUR, and Rachid ZENTAR. "Évaluation de l’acceptabilité environnementale des sédiments en tant que matériaux alternatifs : Application du guide méthodologique." In Conférence Méditerranéenne Côtière et Maritime - Coastal and Maritime Mediterranean Conference. Editions Paralia, 2011. http://dx.doi.org/10.5150/cmcm.2011.023.
Gasiglia, N. "Le traitement des "identifications diachroniques" dans des dictionnaires scolaires français : évaluation de pratiques et proposition de principes de rédaction alternatifs." In Congrès Mondial de Linguistique Française 2008. Les Ulis, France: EDP Sciences, 2008. http://dx.doi.org/10.1051/cmlf08236.
Torres, J. Andres, and Wilhelm Maurer. "Alternatives to Alternating Phase Shift Masks for 65nm." In Photomask Technology 2002, edited by Brian J. Grenon and Kurt R. Kimmel. SPIE, 2002. http://dx.doi.org/10.1117/12.467782.
Dai, Guiping, and Yong Wang. "Non-Alternating ActorGame: Game semantics for actors without alternation." In 2013 IEEE International Conference on Information and Automation (ICIA). IEEE, 2013. http://dx.doi.org/10.1109/icinfa.2013.6720357.
"Front Matter: Volume 7271." In Alternative Lithographic Technologies. SPIE, 2009. http://dx.doi.org/10.1117/12.829689.
"Front Matter: Volume 7970." In Alternative Lithographic Technologies III. SPIE, 2011. http://dx.doi.org/10.1117/12.897034.
"Front Matter: Volume 8680." In Alternative Lithographic Technologies V, edited by William M. Tong and Douglas J. Resnick. SPIE, 2013. http://dx.doi.org/10.1117/12.2021502.
"Front Matter: Volume 9423." In Alternative Lithographic Technologies VII, edited by Douglas J. Resnick and Christopher Bencher. SPIE, 2015. http://dx.doi.org/10.1117/12.2192291.
"Front Matter: Volume 8323." In Alternative Lithographic Technologies IV, edited by William M. Tong. SPIE, 2012. http://dx.doi.org/10.1117/12.928431.
Hanshaw, Geoffrey, and Gary Pope. "Liquefied Natural Gas - Heavy Duty Truck Applications." In Alternative Fuels Conference & Exposition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 1995. http://dx.doi.org/10.4271/952740.
Reports on the topic "Alternatifs":
Brothers, A. J. Alternative comparison, analysis, and evaluation of solid waste and materials system alternatives. Office of Scientific and Technical Information (OSTI), September 1995. http://dx.doi.org/10.2172/205143.
Gomez-Leon, Steve, and Anthony J. Smalley. TR-97-7 Main Bearing Temperature Monitoring. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), April 1998. http://dx.doi.org/10.55274/r0011736.
Soares, Weber. O Impacto das Remessas no Desenvolvimento Econômico Local. Inter-American Development Bank, May 2004. http://dx.doi.org/10.18235/0007866.
Abdelaziz, Omar, Som S. Shrestha, Bo Shen, Randall Lee Linkous, William Goetzler, Matt Guernsey, and Youssef Bargach. Alternative Refrigerant Evaluation for High-Ambient-Temperature Environments: R-22 and R-410A Alternatives for Rooftop Air Conditioners. Office of Scientific and Technical Information (OSTI), September 2016. http://dx.doi.org/10.2172/1326522.
Alarcón López, Luis Guillermo, Rafael Cavazzoni Lima, and Martin Poveda. REAL 5G: Uma alternativa para a renovação de licenças e para implementação de um mercado secundário de espectro radioelétrico no Brasil. Inter-American Development Bank, March 2021. http://dx.doi.org/10.18235/0003112.
Author, Unknown. L52297 Technologies for In-Service Measurement of Seal Gaps in Internal Floating Roof Tanks. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), June 2009. http://dx.doi.org/10.55274/r0010683.
Abdelaziz, Omar, Som S. Shrestha, Jeffrey D. Munk, Randall Lee Linkous, William Goetzler, Matt Guernsey, and Theo Kassuga. Alternative Refrigerant Evaluation for High-Ambient-Temperature Environments: R-22 and R-410A Alternatives for Mini-Split Air Conditioners. Office of Scientific and Technical Information (OSTI), October 2015. http://dx.doi.org/10.2172/1223676.
Abdelaziz, Omar, Jeffrey D. Munk, Som S. Shrestha, Randall Lee Linkous, William Goetzler, Matt Guernsey, and Theo Kassuga. Alternative Refrigerant Evaluation for High-Ambient Temperature Environments: R-22 and R-410A Alternatives for Mini-Split Air Conditioners. Office of Scientific and Technical Information (OSTI), August 2015. http://dx.doi.org/10.2172/1209213.
Romero Ugarte, José Luis, Abel Sánchez Martín, and Carlos Martín Rodríguez. Alternativas a la evolución de la operativa bancaria mayorista en el eurosistema. Madrid: Banco de España, March 2023. http://dx.doi.org/10.53479/29779.
Brown, Jasen, Robert Davinroy, Ivan Nguyen, Aron Rhoads, Nathan Lovelace, Emily Russ, and Jessamin Straub. Tombigbee River : River Miles 81.0-76.0 sediment management study. Engineer Research and Development Center (U.S.), April 2022. http://dx.doi.org/10.21079/11681/43942.