Academic literature on the topic 'Alkoxylation'

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Journal articles on the topic "Alkoxylation"

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Liu, Zhuqing, Fei Huang, Jiang Lou, Quannan Wang, and Zhengkun Yu. "Copper-promoted direct C–H alkoxylation of S,S-functionalized internal olefins with alcohols." Organic & Biomolecular Chemistry 15, no. 26 (2017): 5535–40. http://dx.doi.org/10.1039/c7ob01234a.

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Shen, Jiabin, Jun Xu, Heng Cai, Chao Shen, and Pengfei Zhang. "Platinum(ii)-catalyzed selective para C–H alkoxylation of arylamines through a coordinating activation strategy." Organic & Biomolecular Chemistry 17, no. 3 (2019): 490–97. http://dx.doi.org/10.1039/c8ob02942c.

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Lin, John, Upali Weerasooriya, E. Leach Bruce, Steve V. Orsak, and Park T. X. Cedar. "5627121 Process for preparing alkoxylation catalysts and alkoxylation process." Journal of Molecular Catalysis A: Chemical 125, no. 2-3 (November 1997): 182. http://dx.doi.org/10.1016/s1381-1169(98)80116-7.

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Liu, Lunzu, Guowei Li, and Mingzhi Huang. "ALKOXYLATION OF HYDRIDOPHOSPHORANES." Phosphorus, Sulfur, and Silicon and the Related Elements 69, no. 1-2 (June 1992): 1–6. http://dx.doi.org/10.1080/10426509208036849.

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Weerasooriya, Upali. "Ester alkoxylation technology." Journal of Surfactants and Detergents 2, no. 3 (July 1999): 373–81. http://dx.doi.org/10.1007/s11743-999-0092-5.

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Lakhtin, V. G., V. L. Ryabkov, M. V. Polyakova, V. M. Nosova, A. F. Kisin, and E. A. Chernyshev. "Alkoxylation ofC-chlorovinylsilanes." Russian Chemical Bulletin 44, no. 4 (April 1995): 718–23. http://dx.doi.org/10.1007/bf00698510.

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Rogers, R. L., and K. Hermann. "Upgrading an Alkoxylation Facility." Process Safety and Environmental Protection 82, no. 1 (January 2004): 12–17. http://dx.doi.org/10.1205/095758204322777624.

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Romanova, S. M., A. M. Madyakina, L. A. Fatykhova, and S. V. Fridland. "Alkoxylation of cellulose nitrates." Russian Journal of General Chemistry 83, no. 1 (January 2013): 58–62. http://dx.doi.org/10.1134/s1070363213010106.

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Zhang, Yu-Feng, and Mohamed Mellah. "Samarium(ii)-electrocatalyzed chemoselective reductive alkoxylation of phthalimides." Organic Chemistry Frontiers 9, no. 5 (2022): 1308–14. http://dx.doi.org/10.1039/d1qo01760h.

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Takemura, Noriaki, Yoichiro Kuninobu, and Motomu Kanai. "Copper-catalyzed benzylic C(sp3)–H alkoxylation of heterocyclic compounds." Org. Biomol. Chem. 12, no. 16 (2014): 2528–32. http://dx.doi.org/10.1039/c4ob00215f.

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Dissertations / Theses on the topic "Alkoxylation"

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Arbour, Jannine Louise. "Metal-mediated intramolecular hydroamination and hydro(acy)alkoxylation reactions." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9203.

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This PhD thesis describes work undertaken to effect asymmetric catalysis in hydroamination and hydro(acy)alkoxylation reactions of allenes. The introductory Chapter provides an overview of recent advances in asymmetric heterofunctionalisation reactions of allenes. This includes intra- and inter-molecular reactions involving C-N and C-O bond formations. Chapter 2 begins by comparing the preparation of a γ-allenic alcohol by two different synthetic routes and its subsequent use in intramolecular hydroalkoxylation reactions using copper(II) and silver(I) salts. From this study, the ability of silver diphosphine complexes to facilitate enantioselective hydroalkoxylation reactions in a 5-exo-trig fashion was discovered. Extensive reaction optimisation was undertaken, however only moderate ee’s and conversions were observed. In Chapter 3, the use of other metal Lewis acids to catalyse hydroalkoxylation reactions of γ-allenic alcohols is presented. DFT calculations undertaken by a colleague (Prof H. S. Rzepa) were used to rationalise the observed regioselectivities with silver(I), zinc(II), and tin(II) triflates. From DFT calculations, the metal counteranion was found to be intimately involved in the C-O bond formation. In the following two Chapters, the possibility of asymmetric synthesis by using chiral anionic ligands is discussed. In Chapter 4, additional γ-allenic alcohols and β-allenic acids were synthesised for intramolecular hydroalkoxylation or hydroacyalkoxylation reactions respectively. In Chapter 5, the respective γ-allenic amines were prepared for intramolecular hydroamination. In both cases, the outcome, scope and limitations of the reaction are discussed. In Chapter 6, an overall conclusion and future work is discussed. The last Chapter contains experimental procedures and characterisation data of all the compounds synthesised during the course of this project.
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Diamante, Daria. "Transition metal-catalyzed alkoxylation and amination reactions involving propargyl or allyl derivatives." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066119/document.

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Durant toute ma période de doctorat, passé en co-tutelle entre l'Università degli Studi dell'Insubria et l'UPMC de Paris, j'ai dirigé mes efforts vers l'étude de la formation des liaisons C-O et C-N par de nouvelles réactions catalysées par des métaux de transition.En poursuivant notre projet en cours sur les réactions d'amination et d'alcoxylation catalysées par des métaux de transition intra- et intermoléculaires impliquant la fonctionnalisation C-H, nous avons essayé de réaliser deux procédures d'alcoxylation intramoléculaire de liaisons multiples carbone-carbone pour obtenir des hétérocycles oxygénés et une amination allylique oxydante intermoléculaire pour réaliser des scaffolds azotés.Effectuées au niveau intramoléculaire, les réactions catalysées par des métaux de transition offrent une stratégie polyvalente pour obtenir des molécules cycliques, difficilement obtenues par des méthodes de synthèse conventionnelles et à partir de matériaux de départ facilement disponibles, et représentent l'une des méthodologies clés pour le progrès de la chimie verte et durable.En ce qui concerne les protocoles d'alcoxylation, deux lignées de recherche différentes basées sur la catalyse des métaux de transition appliqués aux réactions de domino ont été étudiées.Les processus domino sont des outils efficaces pour augmenter rapidement la complexité moléculaire par la formation de plus d'une liaison en une seule étape, en respectant la règle de l'économie. Bien que l'approche domino impliquant des alcènes et des allènes soit bien étudiée, des exemples impliquant des alcynes sont quelque peu limités dans la littérature
During the whole period of my PhD, spent in co-tutorship between Università degli Studi dell’Insubria and UPMC in Paris, I have directed my efforts towards the study of C-O and C-N bonds formation by new transition metal-catalyzed reactions.Pursuing our ongoing project on intra- and intermolecular transition metal-catalyzed amination and alkoxylation reactions involving C-H functionalization, we tried to perform two intramolecular alkoxylation procedures of carbon-carbon multiple bonds to obtain oxygenated heterocycles and one intermolecular oxidative allylic amination to accomplish nitrogen-based scaffolds.Performed at intramolecular level, transition metal-catalyzed reactions offer a versatile strategy to obtain cyclic molecules, not easily obtainable by conventional synthetic methods and starting from readily available starting materials, and represent one of the key methodologies for the progress of green and sustainable chemistry. Dealing with alkoxylation protocols, two different research lines based on transition metal catalysis applied to domino reactions were investigated. Domino processes are efficient tools to rapidly increase the molecular complexity through the formation of more than one bond in a single step, respecting the rule of step economy. While the domino approach involving alkenes and allenes is well investigated, examples involving alkynes are somewhat limited in the literature
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Moradi, Alfred. "Organic synthesis via anodically generated iminium cations." Thesis, Queen Mary, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297194.

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GIOFRE', SABRINA. "SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLIC SYSTEMS OF BIOLOGICAL INTEREST THROUGH DOMINO STRATEGIES." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/701960.

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Abstract. In this thesis the synthesis of potentially biologically active heterocyclic compounds has been developed through novel catalytic methods involving C-N and C-O bond forming processes. The thesis consists of three main chapters: a) oxidative intramolecular palladium(II)-difunctionalizations of alkenes (Chapter 1); b) iodine species as a powerful tool in oxidative ring closing reaction (Chapter 2); c) intramolecular rhodium(I) allylic addition to afford α-vinyl-substituted heterocycles (Chapter 3). In Chapter 1.1 an aminoarylation process of allylic ureas has been investigated as a tool to construct 4-substituted imidazolidinones. In the presence of aryltin nucleophiles and hydrogen peroxide as an inexpensive and green oxidant, a 5-exo-regioselective procedure has been developed. On the other hand, when the homoallylic urea is used under similar conditions the seven-membered ring is obtained as a consequence of the β-elimination accountable to a Pd(II)/Pd(0) catalytic cycle. In Chapter 1.2 an intramolecular alkoxyacylation is described employing an hypervalent iodine (III) as both the acylating and oxidizing reagent. A regioselective 6-exo-trig Pd(II)-catalysed cyclisation of N-allyl aminophenol and N-allyl aminoethanol affords benzoxazine and morpholine nuclei, respectively. The synthetic utility of this new products is demonstrated through two-step transformations into purine derivatives, which are used for the treatment and prevention of cancer, and into β-aminoacids. In Chapter 2.1 it is reported the development of an intramolecular domino-type Diels Alder reaction initiated by hypervalent iodine reagents. The employment of N-allyl 2-aminophenols as substrates leads to the formation of a tricyclic system in the sole presence of I(III) species. Moreover, the insertion of various nucleophiles on the α-position of the amino group opens up the way to further unexplored functionalizations. The substrate scope is investigated varying both substituents on the aromatic ring, protective groups and nucleophiles, affording the respective products in 23-67% yields. In Chapter 2.2 a metal-free aminoiodination of O-allyl Ts-protected carbamates is described. Thus, by using hydrogen peroxide and potassium iodide in aqueous media, iodomethyl-substituted heterocycles are obtained in good yields and for selected substrates in a diastereoselective way, too. The reaction proceeds through the formation of an iodonium intermediate with the subsequent attack of the nitrogen in anti. In Chapter 3.1 an intramolecular hydroamination of Ts-protected allenyl amines is investigated. The ability of Rh(I) to catalyse a hydroamination process in a complete selective way, mostly modulating the type of ligand employed, is herein shown. Vinyl-substituted benzoxazine and benzoxazepine have been obtained in good yields and excellent enantioselectivity, as it has never been done before, by employing Josiphos J688-1 ligand and PPTS as co-catalyst. In Chapter 3.2 the results regarding the intramolecular hydroalkoxylation of allenyl alcohols are reported. N-allenyl aminoethanol, N-allenyl aminophenol, allenyl alcohols and allenyl phenols are subjects of our research. Despite the substrate diversity, the chiral ferrocelane diphosphine ligand, (R,R) Me-ferrocelane, is proven optimal for the intramolecular OH-addition to allenes. High yields and good enantioselectivity can be reached varying the Brønsted acid, employed as additive in the reaction. In conclusion, oxidative palladium(II)-catalysed alkene difunctionalizations, hypervalent iodine-promoted dearomatizing intramolecular Diels-Alder reaction, oxidative aminoiodinations and intramolecular enantioselective rhodium(I)-catalysed hydroaminations and alkoxylations of allenes are approaches described in this thesis as valuable methods for the construction of medicinally relevant heterocycles.
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Hall, Charles A. "Kinetics and mass-transfer effects in batch alkoxylations." Thesis, Georgia Institute of Technology, 1987. http://hdl.handle.net/1853/11213.

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Zhang, Shoukun. "Selective C–H Activation by Ruthenium(II) Carboxylate and Nickelaelectro-Catalysis." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2021. http://hdl.handle.net/21.11130/00-1735-0000-0005-155B-E.

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Smith, Paul Craig. "The alkoxylation of biodiesel and its impact on fuel properties." Thesis, 2010. http://hdl.handle.net/2440/61635.

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A property of biodiesel that currently inhibits its use is its relatively poor low-temperature properties, most commonly expressed as cloud point. Improving the low-temperature properties of biodiesel to those for petroleum based diesel will remove one of the few physicochemical barriers to its more widespread application. Improvement of biodiesel low-temperature properties by alkoxylation is a potential method that is investigated in this thesis. While previous work has been performed with model compounds and synthetic laboratory conditions, this work investigates the likely success of a commercial process to produce alkoxylated biodiesel. Process parameters were constrained to atmospheric pressure, low temperatures and reasonable reaction times, while avoiding the use of organic solvents. Epoxidation and alkoxylation of methyl biodiesel produced from canola oil was studied to determine the best conditions while simultaneously developing the analytical methods. A gas chromatography-mass spectrometry method was developed to determine conversion and selectivity for epoxy and alkoxy biodiesel. The best reaction conditions for the epoxidation step, based on conversion and selectivity, and the option of either in-situ generated peroxyformic acid or peroxyacetic acid as the oxygen carrier were determined. Optimal conditions were H₂ O₂ / biodiesel molar ratio of 2:1, acetic acid / biodiesel molar ratio of 0.2:1, acid catalyst to acetic acid / peroxide of 2 wt% and a 6h reaction time at 60°C. The optimal reaction conditions for methyl biodiesel were then transferred to ethyl and butyl biodiesel. An acid catalysed alkoxylation with the same alcohol as the ester head-group was then performed and the cloud point impact was assessed. Alkoxylation of methyl and ethyl biodiesel resulted in reduced low-temperature tolerance while alkoxy butyl biodiesel displayed a slightly improved tolerance. Since butoxylated butyl biodiesel was the most promising in terms of cloud point improvement, the next phase of work was concerned with maximising selectivity for butoxy biodiesel. A range of conditions including reaction time, temperature, catalyst concentration and molar ratio of alcohol were studied. Optimal conditions for the butoxylation of epoxy butyl biodiesel were: 80°C, 2 wt% sulfuric acid and a 40:1 molar ratio of butanol over a period of 1h. Conversion of epoxy butyl biodiesel was 100% and selectivity for butoxy biodiesel was 87.0%. The cloud point of butoxy butyl biodiesel (46% conversion of unsaturated fraction) was identical to that for butyl biodiesel. To determine the impact of higher conversion of unsaturated ester to butoxy ester, a batch of butyl biodiesel was subjected to 30h of epoxidation resulting in a conversion of 93%, corresponding to a butoxy content of 74 wt%. The cloud point of this material was 2°C, representing an increase of 5K over that for butyl biodiesel. Blends of the high conversion batch of butoxy biodiesel showed that cloud point was virtually unchanged at concentrations below 35 wt% and then increased 1K every 8 wt% to approximately 70 wt % butoxy biodiesel. The last phase involved the investigation of the impact of longer and branched side-chains on the properties of butyl biodiesel. Longer straight-chain alcohols were added at the epoxidised double bonds, as were some branched isomers under the optimal conditions determined in phase two. Alcohols included: methanol, ethanol, n-propanol, n-butanol, tert-butanol, n-pentanol, n-hexanol, n-octanol and 2-ethylhexanol. Alkoxylation of butyl biodiesel with methanol, ethanol and propanol increased the cloud and pour point of butyl biodiesel. Alkoxylation with alcohols larger than butanol produced significant improvements in low-temperature properties as indicated by lower cloud and pour points. The lowest cloud point achieved was for ethylhexoxy butyl biodiesel at -6°C, a 6K reduction in cloud point over conventional methyl biodiesel. Alkoxylation also resulted in significant increases in kinematic viscosity, with the viscosity of ethylhexoxy butyl biodiesel being 9.76 mm².s⁻¹, more than double that for methyl biodiesel.
Thesis (Ph.D.) -- University of Adelaide, School of Chemical Engineering, 2010
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Yen-Yi, Hu, and 胡衍毅. "Asymmetric electro-oxidative intramolecular α-alkoxylation of Pyrrolidine : The Synthesis of (-)-Pyrrolidine 197 B And The Synthesis of Trachelanthamidine." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/20378772889149665288.

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Lanier, Megan. "Method Development for the Stereoselective Synthesis of Medium-Sized Cyclic Ethers and Application to Natural Product Synthesis: Part I. Organocatalytic Oxa-Conjugate Addition for α,α´-trans-Oxepanes Part II. Gold(I)-Catalyzed Alkoxylation for α,α´-cis-Oxocenes Part III. Studies toward the Synthesis." Diss., 2015. http://hdl.handle.net/10161/9941.

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Medium-sized cyclic ethers are challenging synthetic targets due to enthalpic and entropic barriers. Methods for the stereoselective synthesis of α,α΄-disubstituted medium-sized cyclic ethers began to appear with the discovery of naturally-occurring, ladder-shaped polycyclic ethers, such as brevetoxin B, and monocyclic ethers, such as (+)-laurencin. Despite the progress made in this field, limitations remain including competing formation of smaller ring sizes and scarcity of catalytic methods. Our aim has been to develop stereoselective syntheses for 7- and 8-membered cyclic ethers which have potential for application in natural product synthesis. The C-O bond disconnection was selected for the methods described within because cyclization and stereoinduction could be achieved simultaneously. In the case of 7-membered cyclic ethers, an organocatalytic oxa-conjugate addition reaction promoted by the gem-disubstituent (Thorpe−Ingold) effect has been developed to stereoselectively provide α,α′-trans-oxepanes. A gold(I)-catalyzed alkoxylation reaction has also allowed access to α,α′-cis-oxocenes. This method has been probed for feasibility in the stereoselective synthesis of (+)-intricenyne, an 8-membered cyclic ether belonging to the C15 nonterpenoid acetogenin natural product class. These methods have the potential to become general and efficient routes to highly functionalized oxepanes and oxocenes.


Dissertation
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Book chapters on the topic "Alkoxylation"

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Caiado, M., D. S. Pito, and J. E. Castanheiro. "Alkoxylation of Terpenes over Tungstophosphoric Acid Immobilised on Silica Support." In Environmentally Benign Catalysts, 153–64. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6710-2_7.

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Stadlbauer, W. "Alkoxylation." In Five-Membered Hetarenes with Two Nitrogen or Phosphorus Atoms, 1. Georg Thieme Verlag KG, 2002. http://dx.doi.org/10.1055/sos-sd-012-00362.

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Sapeta, K., and M. A. Kerr. "Alkoxylation." In Science of Synthesis Knowledge Updates KU 2011/1, 1. Georg Thieme Verlag KG, 2011. http://dx.doi.org/10.1055/sos-sd-112-00091.

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Camp, J. E. "C-Alkoxylation." In Six-Membered Hetarenes with Two Unlike or More than Two Heteroatoms and Fully Unsaturated Larger-Ring Heterocycles, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-117-00064.

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Soenen, D. R., and C. D. Vanderwal. "Photochemical Alkoxylation." In Ethers, 1. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-037-00108.

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Sato, N. "Hydroxylation and Alkoxylation." In Six-Membered Hetarenes with Two Identical Heteroatoms, 1. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00974.

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Sato, N. "Hydroxylation, Alkoxylation, and Sulfanylation." In Six-Membered Hetarenes with Two Identical Heteroatoms, 1. Georg Thieme Verlag KG, 2011. http://dx.doi.org/10.1055/sos-sd-116-00487.

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Soenen, D. R., and C. D. Vanderwal. "Radical Alkoxylation of Alkenes." In Ethers, 1. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-037-00113.

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Soenen, D. R., and C. D. Vanderwal. "Electrochemical Alkoxylation of Alkenes." In Ethers, 1. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-037-00114.

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Sato, N. "Hydroxylation, Alkoxylation, and Sulfanylation." In Six-Membered Hetarenes with Two Identical Heteroatoms, 1. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00986.

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Conference papers on the topic "Alkoxylation"

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Carreira de Rezende, Fabiola, Rodrigo Balloni Rabelo, Lilian Kinouti, Conrado Gerard Ewbank, and Olivia Cueva Candido Poltronieri. "Tailoring Alkoxylation of Flowback Aid Surfactants for Maximum Efficiency." In SPE International Conference on Oilfield Chemistry. Society of Petroleum Engineers, 2019. http://dx.doi.org/10.2118/193623-ms.

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Nohr, Marcus, Tilman Utz, and Knut Graichen. "Kinetic modelling of an industrial semi-batch alkoxylation reactor for control studies." In 2014 UKACC International Conference on Control (CONTROL). IEEE, 2014. http://dx.doi.org/10.1109/control.2014.6915210.

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Xu, Zhen, Jinsheng Zhao, and Weiyu Fan. "Chemosynthesis and photoelectric characterization of a novel solution-processable electrochromic copolymer based on alternating alkoxylating benzene and benzo[1,2-b:4,5-b']dithiophene derivatives." In 2015 2nd International Workshop on Materials Engineering and Computer Sciences. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/iwmecs-15.2015.120.

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