Relevant bibliographies by topics / Alkaloids

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Alkaloids'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Alkaloids"

1

Han, Sunkyu, Sangbin Jeon, and Joonoh Park. "Syntheses of Dimeric Securinega Alkaloids." Synlett 28, no. 18 (August 22, 2017): 2353–59. http://dx.doi.org/10.1055/s-0036-1590864.

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The isolation of flueggenines A and B by Yue and co-workers in 2006 has triggered a burst of isolation reports of dimeric and oligomeric securinega alkaloid natural products. The compelling molecular structures of these compounds with various modes of connection between monomeric securinega units have posed intriguing challenges to the synthetic organic community. Herein, we have categorized high-order securinega alkaloids based on their biosynthetic mode of dimerization or oligomerization. We then have compiled all reported syntheses of dimeric securinega alkaloids based on our classification.1 Introduction2 Categorization of High-Order Securinega Alkaloid Natural Products3 Syntheses of Type I Dimeric Securinega Alkaloids4 Syntheses of Type II Dimeric Securinega Alkaloids5 Synthesis of Type III Dimeric Securinega Alkaloid6 Conclusion
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Věžník, František, Eva Táborská, Hana Bochořáková, František Tureček, Vladimír Hanuš, and Jiří Slavík. "Alkaloids of Papaver nudicaule SUBSP. xanthopetalum (TRAUTV.) FEDDE and P. nudicaule SUBSP. album (REGEL) FEDDE from the section Scapiflora REICHB." Collection of Czechoslovak Chemical Communications 52, no. 6 (1987): 1634–40. http://dx.doi.org/10.1135/cccc19871634.

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The alkaloidal composition in the two title taxa differs only quantitatively. Both contain amurine as the main alkaloid. P. nudicaule ssp. xanthopetalum contains muramine, protopine and alkaloid PN1 (probably identical with (±)-nudaurine (Ia)) as dominant alkaloids; further were isolated amurensine, epialpinine, cryptopine, mecambridine and alpinigenine. Allocryptopine, papaverrubines A, B, D and G, palmatine and coptisine were detected chromatographically. The quaternary alkaloid fraction afforded cis-N-methylstylopinium hydroxide (as the iodide II) which was isolated for the first time from P. nudicaule. In P. nudicaule ssp. album the alkaloid PN1, epialpinine, amurensine and muramine represented the dominant alkaloids, accompanied with mecambridine, protopine, cryptopine, allocryptopine and alpinigenine. Among the quaternary alkaloids N-methylstylopinium hydroxide was found.
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El-Shazly, Assem. "Pyrrolizidine Alkaloid Profiles of Some Senecio Species from Egypt." Zeitschrift für Naturforschung C 57, no. 5-6 (June 1, 2002): 429–33. http://dx.doi.org/10.1515/znc-2002-5-604.

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Alkaloid profiles of two Egyptian Senecio species (Senecio aegyptius var. discoideus and S. desfontainei) in addition to a cultivated species (S. cineraria) were studied using capillary GLC and GLC-mass spectrometry with respect to pyrrolizidine alkaloids (PAs). Four alkaloids were identified in S. aegyptius var. discoideus, 8 in S. desfontainei and 13 in S. cineraria. Some of these alkaloids have not been reported from these plants. The alkaloidal pattern of different plant organs (flowers, leaves, stem, root) were also investigated. Senecionine has been found to be a one of the major alkaloid in all studied species, it was isolated and its structure was elucidated by 1H- and 13C-NMR.
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El-Shazly, A., A. M. Ateya, L. Witte, and M. Wink. "Quinolizidine Alkaloid Profiles of Retama raetam, R. sphaerocarpa and R. monosperma." Zeitschrift für Naturforschung C 51, no. 5-6 (June 1, 1996): 301–8. http://dx.doi.org/10.1515/znc-1996-5-607.

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Abstract About 28 quinolizidine alkaloids and the dipiperidine alkaloids am modendrine, dehydroammodendrine and N -formylammodendrine were identified in the alkaloidal extracts of Retama raetam, Retama sphaerocarpa and Retama monosperma by capillary GLC and GLCMS. Alkaloid profiles of the three Retama species with a Mediterranean distribution are more similar than alkaloid patterns of different organs of the same plant. Whereas sparteine and retamine are the major components of stems, lupanine, retam ine, N-methylcytisine and cytisine dominate in flowers and pods, and cytisine in seeds indicating a high degree of organ specificity of alkaloid storage.
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Slavík, Jiří, and Leonora Slavíková. "Alkaloids of Meconopsis cambrica (L.) VIG. and M. robusta HOOK. f. et THOMS." Collection of Czechoslovak Chemical Communications 61, no. 12 (1996): 1815–22. http://dx.doi.org/10.1135/cccc19961815.

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Additional alkaloids (+)-roemerine (3b), (+)-corytuberine (3d), (-)-N-methylmecambridinium and alkaloid MC 2 (the last two as iodides) were isolated as minor alkaloidal components from Meconopsis cambrica (L.) VIG. (Papaveraceae) besides of the dominant known alkaloids (-)-mecambrine (1), (-)-mecambridine (2), (-)-flavinantine (4) and (+)-magnoflorine (5), and a small amount of (+)-mecambroline (3a). Minute quantities of protopine, allocryptopine, roemeroline, papaverrubine D and C, berberine, coptisine, corysamine and palmatine were identified by thin layer chromatography (TLC). From M. robusta HOOK. f. et THOMS., protopine, (-)-amurensinine (6) and two incompletely characterized alkaloids MRO 1 and MRO 2 were isolated, and allocryptopine, cryptopine, rhoeadine, 6-methoxy-2-methyl-1,2,3,4-tetrahydro-β-carboline, alkaloid MR 1, coptisine, corysamine, magnoflorine, corytuberine and N-methylamurensininium salt were detected on TLC.
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Sreevidya, Narasimhan, and Shanta Mehrotra. "Spectrophotometric Method for Estimation of Alkaloids Precipitable with Dragendorff's Reagent in Plant Materials." Journal of AOAC INTERNATIONAL 86, no. 6 (November 1, 2003): 1124–27. http://dx.doi.org/10.1093/jaoac/86.6.1124.

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Abstract A rapid, easy, and simple spectrophotometric method was developed for the estimation of total alkaloids precipitated by Dragendorff's reagent (DR) in plant materials. It is based on the formation of yellow bismuth complex in nitric acid medium with thiourea. The yellow-colored complex formed obeys Lambert-Beer's law in the concentration range of 0.06–50 μg/mL with λmax at 435 nm. Using this method, the alkaloidal percentage of certain alkaloids (ajamalicine, papaverine, cinchonine, piperine, berberine) and some plant materials containing alkaloids (Berberis aristata, Solanum nigrum, and Piper longum) were determined. The method was compared with other methods. It can be used for routine analysis of commercial samples by industries dealing with herbal drugs for standardization of plant materials containing alkaloids and for alkaloid-containing pharmaceutical products.
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Lim, Hyeonggeun, Sikwang Seong, and Sunkyu Han. "Syntheses of Post-Iboga Alkaloids." Synthesis 51, no. 14 (February 19, 2019): 2737–58. http://dx.doi.org/10.1055/s-0037-1612061.

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Post-iboga alkaloids are secondary metabolites that are biosynthetically derived from iboga-type alkaloids via rearrangements of the indole and/or isoquinuclidine moieties. Herein, we categorize post-iboga alkaloids into five types based on the biosynthetic mode of transformation of the iboga scaffold. We then describe reported syntheses of post-iboga alkaloids, including our laboratory’s recent contributions, based on our own categorization.1 Introduction1.1 Iboga and Post-Iboga Alkaloids1.2 Classification of Post-Iboga Alkaloids1.2.1 Introduction to Type I Post-Iboga Alkaloids1.2.2 Introduction to Type II Post-Iboga Alkaloids1.2.3 Introduction to Type III Post-Iboga Alkaloids1.2.4 Introduction to Type IV Post-Iboga Alkaloids1.2.5 Introduction to Type V Post-Iboga Alkaloids2 Syntheses of Post-Iboga Alkaloids2.1 Syntheses of Type I Post-Iboga Alkaloids2.1.1 Syntheses of Monomeric Type I Post-Iboga Alkaloids2.1.2 Syntheses of Dimeric Type I Post-Iboga Alkaloids2.2 Syntheses of Type II Post-Iboga Alkaloids2.3 Synthetic Studies Toward Type III Post-Iboga Alkaloids2.4 Syntheses of Type IV Post-Iboga Alkaloids2.5 Synthesis of Type V Post-Iboga Alkaloids3 Conclusion and Outlook
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Wink, M., and L. Witte. "Quinolizidine Alkaloids as Nitrogen Source for Lupin Seedlings and Cell Cultures." Zeitschrift für Naturforschung C 40, no. 11-12 (October 1, 1985): 767–75. http://dx.doi.org/10.1515/znc-1985-11-1204.

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Abstract The alkaloid patterns during germination and seedling development of Lupinus polyphyllus, L. angustifolius, L. albus, L. pubescens, Cytisus scoparius, Baptisia australis, Spartium junceum and Laburnum anagyroides were studied by capillary glc and EI-MS and CI-MS. The alkaloid contents were relatively high in the seeds and decreased by 20-100% during germination and the early developmental stages. The plants with fully developed leaves were able to synthesize new alkaloids. The decrease of alkaloid concentrations during germination was interpreted in terms of alkaloid turnover and use of the alkaloidal nitrogen for seedling development. The ability of plants to rely on the alkaloidal nitrogen as a nitrogen source could also be shown in lupin cell cultures which could survive and even grow on media which contained sparteine as the sole nitrogen source.
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El-Shazly, Assem, Abdel-Monem M. Ateya, and Michael Wink. "Quinolizidine Alkaloid Profiles of Lupinus varius orientalis, L. albus albus, L. hartwegii, and L. densiflorus." Zeitschrift für Naturforschung C 56, no. 1-2 (February 1, 2001): 21–30. http://dx.doi.org/10.1515/znc-2001-1-204.

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Abstract Alkaloid profiles of two Lupinus species growing naturally in Egypt (L. albus albus [synonym L. term is], L. varius orientalis) in addition to two New World species (L. hartwegii, L. densiflorus) which were cultivated in Egypt were studied by capillary GLC and GLC-mass spectrometry with respect to quinolizidine alkaloids. Altogether 44 quinolizidine, bipiperidyl and proto-indole alkaloids were identified; 29 in L. albus, 13 in L. varius orientalis, 15 in L. hartwegii, 6 in L. densiflorus. Some of these alkaloids were identified for the first time in these plants. The alkaloidal patterns of various plant organs (leaves, flowers, stems, roots, pods and seeds) are documented. Screening for antimicrobial activity of these plant extracts demonstrated substantial activity against Candida albicans, A spergillus flavus and Bacillus subtilis.
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Marsi Mbayo Kitambala, Emery Kalonda Mutombo, Blandine Nkiko Niyibizi, Grégoire Sangwa Kamulete, Glauber Mbayo Kalubandika, Jean Mulamba Muidikija, Evodie Numbi wa Ilunga, et al. "The in vitro antisickling effect of purified alkaloids of Cremaspora triflora (Thonn.) K. Schum. (Rubiaceae) and Macaranga schweinfurthii Pax. (Euphorbiaceae)." World Journal of Advanced Research and Reviews 9, no. 3 (March 30, 2021): 129–37. http://dx.doi.org/10.30574/wjarr.2021.9.3.0074.

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Introduction and objective: Sickle cell disease is an inherited pathology to an abnormality of hemoglobin precisely hemoglobin S for which there is no curative therapy. It mainly affects sub-Saharan African and Caribbean populations. Thus, this study aims to make the phytochemical screening of Cremaspora triflora and Macaranga schweinfurthii as well as to evaluate the antisickling activity of their purified alkaloids. Methodology: Chemical screening was performed using color and precipitation tests as well as the foam index method. The extraction of the alkaloids was carried out with organic solvents in a basic medium while the purification by open column chromatography. The evaluation of the antisickling activity was carried out by Emmel’s test. Results: The chemical screening highlighted alkaloids, steroids, saponins, tannins, and terpenoids in the species studied. Flavonoids and anthocyanins were present in organs of Macaranga schweinfurthii, but absent in Cremaspora triflora. The extraction showed that Macaranga schweinfurthii leaves contained 0.59% alkaloids and 0.73% alkaloids in Cremaspora triflora leaves. The alkaloids purification allowed to obtain an alkaloidal fraction MS1 (1.24 g, 70.05%) from Macaranga schweinfurthii and two fractions [CT2 (0.934 g, 63.97%) and CT3 (0.006 g, 0.41 %)] from Cremaspora triflora which tested positive with Dragendorff and Wagner reagents. The antisickling activity evaluation showed that the SIR varied between 36.00% (0.25 mg/ml) and 90.66% (1 mg/ml) for the alkaloid solutions of Cremaspora triflora (IC50 of 0.51 mg/ml) as well as between 4.00% (0.25 mg/ml) and 33.33% (1 mg/ml) for the alkaloid solutions of Macaranga schweinfurthii (IC50 of 1.40 mg/ml). Conclusion: This study showed that the purified alkaloids of the studied plant species have an inhibitory power on sickling.
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Dissertations / Theses on the topic "Alkaloids"

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Witt, Anette. "Synthetic development towards benzodiazepine alkaloids : total synthesis of circumdatin F and C /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-077-6/.

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Callaghan, Owen. "Synthetic and mechanistic studies in free radical." Thesis, University of Strathclyde, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366957.

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Kalusa, Andrew. "Synthesis of marine alkaloids." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275274.

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Goddard, Euan. "Asymmetric Synthesis of Alkaloids." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.489446.

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Smith, Catherine Janet. "Synthesis of histrionicotoxin alkaloids." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620245.

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Brock, Elizabeth Anne. "Alkaloids from transannular iodoaminations." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:0feddc99-0fde-4dcd-b717-b0c6b0515615.

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This thesis is concerned with the development of transannular iodoamination methodology for the synthesis of pyrrolizidine, indolizidine and tropane alkaloids. Chapter 1 introduces the concept of a ‘transannular cyclisation’ and outlines the utility of such cyclisations in the synthesis of a range of [x.y.z]-azabicyclic alkaloids. Chapter 2 describes the development of a three step lithium amide conjugate addition, ring-closing metathesis and transannular iodoamination protocol for the preparation of the pyrrolizidine scaffold ([3.3.0]-azabicycle). Cyclisation of a hexahydroazocine occurs with concomitant N-debenzylation to give a single diastereoisomer of the corresponding C(7)-iodopyrrolizidine product, which is then elaborated to the known pyrrolizidine, (−)-7a-epi-hyacinthacine A1. Chapter 3 delineates an extension of the methodology described in Chapter 2, and an investigation into accessing alternate diastereoisomeric pyrrolizidine scaffolds via the transannular iodoamination process. These studies culminate in the synthesis of two pyrrolizidine alkaloids, (−)-hyacinthacine A1 and (−)-hyacinthacine A2. Chapter 4 details investigations into the further elaboration of the C(7)-iodopyrrolizidine scaffold synthesised in Chapter 2. A nucleophilic displacement reaction with azide leads to the synthesis of novel 7-deoxy-7-aminoalexine analogues, whilst radical-mediated substitution of the iodide by oxygen allows the synthesis and isolation of the pyrrolizidine alkaloid (−)-1-epi-alexine. Chapter 5 outlines the development of the transannular iodoamination reaction to facilitate the synthesis of the tropane architecture ([3.2.1]-azabicycle). A tandem lithium amide conjugate addition and aldol reaction sequence is followed by ring-closing metathesis to give the required aminocycloheptene. Subsequent treatment with iodine results in transannular cyclisation to give a single iodotropane product which, following elaboration culminates in the synthesis of (+)-pseudococaine. Chapter 6 contains full experimental procedures and characterisation data for all compounds synthesised in Chapters 2, 3, 4 and 5.
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Stanley, Paul. "Semisynthesis of jerantinine alkaloids." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/47504/.

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This thesis details the synthetic studies undertaken on natural products with anti-cancer activity. The general aim was to explore the synthesis and find an efficient and effective method to generate compounds, which would be used to further examine novel biological action. The first half of this thesis details the synthetic studies on the jerantinine family of natural products. The approach utilised the complex alkaloid (-)-tabersonine as a starting material, which was isolated from an abundant and sustainable source. Ultimately the first synthesis of (-)-jerantinine A and first enantioselective synthesis of (-)-jerantinine E were achieved. The biological activity of the synthetic material proved to be identical to that isolated from natural sources. The final part of this work describes the synthesis of a series of compounds derived from piperlongumine, which is of the Piperaceae family of natural products. The synthesis was accomplished using a novel methodology, which enabled the generation of a focussed library of derivatives. The compounds were tested by collaborators and their anti-cancer activity assessed in a variety of cell lines, revealing features of the structure activity relationship.
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Choi, Joong-Kwon. "Synthesis of pyrrolizidine alkaloids /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487259125219504.

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Saensuk, Pilan. "Phytochemistry of norditerpenoid alkaloids." Thesis, University of Bath, 2007. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485128.

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Norditerpenoid alkaloids have important biological activities. Many of them are potent ligands and therefore promising leads for novel selective antagonists and/or agonists of subtypes of nicotinic acetylcholine receptors (nAChR) and voltage-gated sodium channels. Aconitum, Consolida, and Delphinium are important sources of norditerpenoid alkaloids. This thesis is focussed on the chemistry of norditerpenoid alkaloids from these three genera, starting with a review of those recently isolated from Aconitum, Consolida, and Delphinium with brief aspects of taxonomy, biological activities, and modes of action. Selected aspects of the uses in traditional medicine of Delphinium and Aconitum are presented, including data on both toxicity and detoxification. In this thesis, chemical constituents of the seeds of Delphinium cultivar Pacific Giant and the seeds ofAconitum lycoctonum were investigated. To extract the crude alkaloidal material, Soxblet extraction was used for Delphinium cv Pacific Giant seeds and room temperature extraction for A. lycoctonum seeds. The crude extracts were purified by repeated column chromatography (over silica and alumina gels), yielding five known norditerpenoid alkaloids from Delphinium cv Pacific Giant (delavaines A and B, delpheline, methyllycaconitine (MLA), and pacinine) and two from A. lycoctonum (lycaconitine and N-succinylanthranoyl lycoctonine) which were analysed by detailed spectroscopic methods. X-Ray crystallographic analysis of aconitine, mesaconitine, lycoctonine, and delpheline was also studied. Three compounds were obtained from semisynthesis starting with MLA: lycoctonine by basic hydrolysis, inuline by acidic hydrolysis and by esterification of lycoctonine, and elatine by methylenedioxy acetal fonnation. These known alkaloids were structurally elucidated by a variety of spectroscopic techniques. MLA is a selective competitive antagonist at 0.7 sub-type nAChR. From collaborative studies, the results of biological activity for methyl esters delavaines A and B (a 3:2 mixture), delpheline'iand pacinine (the B-ring C6-ketone of delpheline) are reported in this thesis. Their biological activities were detennined in competitive o.-bungarotoxin binding assays for 0.7 nAChR in rat brain membranes. Delavaines A and B were potent ligands (ICso = 50 nM, cfMLA ICso =-1-2 nM), whereas delpheline and pacinine displayed only modest activity at 0.7 nAChR (ICso = -1 JlM). After studying N-ethylpiperidine as a model alkaloid, the pKa (a key physico-chemical parameter) ofMLA was measured by IH NMR as 7.15. A brief comparison with pKa data reported in the literature IS made across closely related norditerpenoid alkaloids.
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Sedlock, Andrea B. "Ergot alkaloids and herbivory in model animals and variation in an ergot alkaloid biosynthesis gene." Morgantown, W. Va. : [West Virginia University Libraries], 2003. http://etd.wvu.edu/templates/showETD.cfm?recnum=3190.

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Thesis (M.S.)--West Virginia University, 2003.
Title from document title page. Document formatted into pages; contains viii, 62 p. : ill. (some col.) Vita. Includes abstract. Includes bibliographical reference.
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Books on the topic "Alkaloids"

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Roberts, Margaret F., and Michael Wink, eds. Alkaloids. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4757-2905-4.

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Linskens, Hans Ferdinand, and John F. Jackson, eds. Alkaloids. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-84226-9.

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Cordell, Geoffrey A. The Alkaloids, Volume 59 (The Alkaloids) (The Alkaloids). Academic Press, 2002.

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The Alkaloids, Volume 59 (The Alkaloids) (The Alkaloids). Academic Press, 2002.

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Knölker, Hans-Joachim. Alkaloids. Elsevier Science & Technology Books, 2017.

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Knolker, Hans-Joachim. Alkaloids. Elsevier Science & Technology Books, 2015.

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Cordell, Geoffrey A. Alkaloids. Elsevier Science & Technology Books, 2003.

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Qin, Hailin, and Dequan Yu. Alkaloids. De Gruyter, 2021. http://dx.doi.org/10.1515/9783110627299.

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Alkaloids. Elsevier, 2015. http://dx.doi.org/10.1016/c2011-0-04166-2.

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Alkaloids. Elsevier, 2015. http://dx.doi.org/10.1016/c2012-0-07416-9.

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Book chapters on the topic "Alkaloids"

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Pengelly, Andrew. "Alkaloids." In The constituents of medicinal plants, 168–201. 3rd ed. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789243079.0010.

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Abstract Found in roots, rhizomes, leaves, bark, fruit or seeds of 15-30% of all flowering plants, alkaloids are particularly common in certain families, such as the Fabaceae, Rubiaceae, Ranunculaceae, Apocynaceae, Solanaceae and Papaveraceae. Over 20,000 different alkaloids have been isolated from over 300 plant families. Over 150 alkaloids are known to occur in one species, Catharanthus roseus (Apocynaceae). The most widely occurring plant alkaloids are caffeine and berberine. This paper discusses the properties, nomenclature, pharmacological actions and classification of alkaloids. Tabulated data are given on major alkaloidal groups, with examples and actions.
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Makkar, Harinder P. S., P. Siddhuraju, and Klaus Becker. "Alkaloids." In Plant Secondary Metabolites, 107–11. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-425-4_18.

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Böttger, Angelika, Ute Vothknecht, Cordelia Bolle, and Alexander Wolf. "Alkaloids." In Lessons on Caffeine, Cannabis & Co, 179–203. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-99546-5_12.

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Leonard, J. "Alkaloids." In The Chemistry of Natural Products, 218–58. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2144-6_6.

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Fox, Malcolm A. "Alkaloids." In Glossary for the Worldwide Transportation of Dangerous Goods and Hazardous Materials, 7. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-11890-0_4.

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Herbert, R. B. "Alkaloids." In The Biosynthesis of Secondary Metabolites, 120–81. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-010-9132-9_6.

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Buckingham, J., and R. A. Hill. "Alkaloids." In Atlas of Stereochemistry, 103–14. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4899-3420-8_4.

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Bhutani, S. P. "Alkaloids." In Chemistry of Biomolecules, 397–441. Second edition. | Boca Raton : CRC Press, 2019.: CRC Press, 2019. http://dx.doi.org/10.1201/9780429266423-7.

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Bruce, Neil C. "Alkaloids." In Biotechnology, 326–61. Weinheim, Germany: Wiley-VCH Verlag GmbH, 2008. http://dx.doi.org/10.1002/9783527620906.ch7.

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Gooch, Jan W. "Alkaloids." In Encyclopedic Dictionary of Polymers, 873. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_13089.

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Conference papers on the topic "Alkaloids"

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Seijas, Julio, M. Vázquez-Tato, Javier Seijo-Muras, Pablo Ramil-Rego, and M. Buján. "Alkaloids from Narcissus bulbocodium L." In The 8th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01978.

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Yunusov, M. S., E. M. Tsyrlina, S. A. Kryzhanovsky, I. B. Tsorin, and S. G. Yunusova. "ANTIARRHYTHMICS BASED ON DITERPENOID ALKALOIDS." In MedChem-Russia 2021. 5-я Российская конференция по медицинской химии с международным участием «МедХим-Россия 2021». Издательство Волгоградского государственного медицинского университета, 2021. http://dx.doi.org/10.19163/medchemrussia2021-2021-133.

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Seijas, Julio, M. Vázquez-Tato, M. Linares, Pablo Ramil-Rego, and M. Buján. "Mesembrine Alkaloids from Narcissus triandrus L." In The 8th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01979.

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Trauner, Dirk, Johann Mulzer, Jan Bats, Stefanie Porth, and Till Opatz. "Total Synthesis of Morphine- and Hasubanane Alkaloids." In The 1st International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 1997. http://dx.doi.org/10.3390/ecsoc-1-02045.

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Wipf, Peter, and Filip Petronijevic. "New Approaches to Indoles and Indole Alkaloids." In 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0388-1.

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Cheng, YB, CJ Su, SR Chen, and CY Chen. "New Alkaloids from Taiwanese Zoanthid Palythoa tuberculosa." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608091.

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Kaya, Gİ, K. Uzun, S. Demir, B. Bozkurt, MA Onur, and N. Unver Somer. "Isolation of further alkaloids from Galanthus cilicicus." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608244.

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Som, Ayub Md, Norizan Ahmat, Hairul Amani Abdul Hamid, Siti Raihanah Abdul Rahman, Nurul Amirrah Rahimudin, Nur Amira Zainidi, and Adilah Amirah Ayub. "Phytochemical Screening and Antioxidant Activity of <i>Hylocereus undatus</i> Foliage: Effects of Using Different Drying and Assays Methods." In 5th International Conference on Global Sustainability and Chemical Engineering 2021 (ICGSCE2021). Switzerland: Trans Tech Publications Ltd, 2023. http://dx.doi.org/10.4028/p-m2r02u.

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Phytochemical screening was conducted on Hylocereusundatus foliage to determine the presence of alkaloids, flavonoids, tannins, and saponins using methanol and chloroform solvents via oven-dried and open air-dried methods. As for the antioxidant activity, powdered Hylocereusundatus foliage were extracted using both solvents through Ferric Reduction Antioxidant Power (FRAP) assay; and the findings were then compared to 2,2-Diphenyl-1-Ipicrylhydrazyl (DPPH) assay from previous studies. Results revealed that for both methods in phytochemical screening, flavonoids were present only in methanol extract; however, saponins were present in both extracts. No alkaloid and tannins were present in both extracts using both methods. Antioxidant activity results revealed that the methanol extract (59.05%) and chloroform extract (20.58%) using the FRAP assay were comparable to that of DPPH assay in which methanol extract (88.81%) and chloroform extract (38.30%) were obtained. It concludes that Hylocereusundatus has comparable phytochemical constituents and antioxidant activity based on the different drying and assay methods.
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Petrovic, Aleksandra, Gorica Vukovic, Tijana Stojanovic, Dušan Marinkovic, Bojan Konstantinovic, Bojana Špirovic-Trifunovic, Željka Jeličic Marinkovic, and Vojislava Bursic. "OCCURRENCE OF TROPANE ALKALOIDS IN MAIZE DUE TO THE PRESENCE OF SOLANACEAE FAMILY." In XXVI savetovanje o biotehnologiji sa međunarodnim učešćem. University of Kragujevac, Faculty of Agronomy, 2021. http://dx.doi.org/10.46793/sbt26.297p.

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Tropane alkaloids are considered to be serious health hazard for humans and that their maximum residue levels in food and feed are still not established. In this paper five samples of maize collected from the local producer in 2020 have been investigated by the liquid chromatography with tandem mass spectrometry (LC-MS/MS) for the atropine and scopolamine determination. The detected concentrations of atropine and scopolamine were extremely high (17.7-67.0 μg/kg for atropine and 2.3-10.4 μg/kg for scopolamine). The obtained results show the seriousness of the tropane alkaloids problem in maize as well as the need for monitoring and further research.
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Gámiz-Gracia, Laura, Natalia Arroyo-Manzanares, Vicente Rodríguez-Estévez, and Ana M. García-Campaña. "Occurrence of principal ergot alkaloids in swine feeding." In 1st International Electronic Conference on Toxins. Basel, Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/iect2021-09152.

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Reports on the topic "Alkaloids"

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Pereboom, D. P. K. H., P. P. J. Mulder, M. Sopel, and J. Grzetic. Proficiency test for ergot alkaloids in cereals : EURLPT-MP08 (2022). Wageningen: Wageningen Food Safety Research, 2023. http://dx.doi.org/10.18174/636591.

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Pereboom, D. P. K. H., A. Veršilovskis, P. P. J. Mulder, M. de Nijs, and J. G. J. Mol. Proficiency test for ergot alkaloids in cereals : EURL-PT-MP03 (2019). Wageningen: Wageningen Food Safety Research, 2020. http://dx.doi.org/10.18174/526444.

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Pereboom, D. P. K. H., W. C. M. de Nijs, and P. P. J. Mulder. Proficiency test for tropane alkaloids in food and feed matrices : EURLPT-MP04 (2020). Wageningen: Wageningen Food Safety Research, 2021. http://dx.doi.org/10.18174/544466.

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Pereboom, D. P. K. H., M. de Nijs, J. G. J. Mol, and P. P. J. Mulder. Research study for pyrrolizidine alkaloids in alfalfa and herbal tea : EURLPT-MP02 (2019). Wageningen: Wageningen Food Safety Research, 2021. http://dx.doi.org/10.18174/545714.

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Pereboom, D. P. K. H., P. P. J. Mulder, M. Sopel, and J. Grzetic. Proficiency test for opium alkaloids in poppy seeds and bakery products : EURLPT-MP09 (2023). Wageningen: Wageningen Food Safety Research, 2023. http://dx.doi.org/10.18174/641239.

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Annunziato, Dominick. HPLC Sample Prep and Extraction SOP v1.3 for Fungi. MagicMyco, August 2023. http://dx.doi.org/10.61073/sopv1.3.08.11.2023.

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medicine, industry, and biotechnology. Fungi produce a wide range of bioactive compounds, such as alkaloids, antibiotics, antifungals, immunomodulators, anticancer agents, enzymes, and vitamins. However, these compounds are often locked inside the fungal cell wall, which is composed of chitin, a tough substance that is dif�icult to digest by humans1. Therefore, it is essential to have a good extraction technique that can break down the chitin and release the valuable compounds from the fungi, this is especially essential in the laboratory for accurate lab assays and potency determination during routine HPLC chromatography analysis. During licensure and/ or certi�ication any given lab will be required to take a pro�iciency test which gauges the lab’s pro�iciency at measuring a given matrices for accurate evaluation. They evaluate our abilities to run the gear and accurately measure the potency of what was extracted; however, at the time of this writing none existed for extraction of the fungal material itself, so this remains a variable between testing labs. It is important that we openly share our extraction techniques for evaluating fungi materials speci�ically for the clean extraction of active alkaloids for which potency can be measure via chromatography and/or spectrometry devices. In this way hopefully creating less variables between testing lab and more concise results. In this paper, we present a novel sample prep and extraction technique for fungi that uses speci�ic solvent composition in conjunction with M.A.E (microwave assisted extraction) in 75% methanol , 25% water which helps break the cell wall to release the compounds. Also used is an ultrasonication unit and vortex mixer. Our technique quickly releases all the available alkaloids for accurate chromatography measurements in just two hours, forty-�ive minutes with minimal handling. We demonstrate the effectiveness and ef�iciency of our technique by applying it to magic mushroom fruit bodies for the extraction of tryptamines namely psilocybin and its active derivative psilocin; however, this technique can be used for other species of fungi and compounds like Cordyceps/ cordycepin or Lions’ mane/ erinacines, etc.. We also compare our technique with other popular methods in terms of extraction techniques, digestion times and solvent compositions. Our results show that our technique is superior to the others in terms of time and effectiveness while pulling all the active compounds and not degrading them. Our extraction technique for fungi chromatography analysis offers a new and improved way to access the natural products of fungi and explore their potential for various biotechnological applications. We hope that our technique will inspire further research and innovation in the field of fungal extraction and natural product.
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Committee on Toxicology. New Approach Methodologies (NAMs) In Regulatory Risk Assessment Workshop Report 2020- Exploring Dose Response. Food Standards Agency, March 2024. http://dx.doi.org/10.46756/sci.fsa.cha679.

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The UK Food Standards Agency (FSA) and the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) held an “Exploring Dose Response” workshop in a multidisciplinary setting inviting regulatory agencies, government bodies, academia and industry. The workshop provided a platform from which to address and enable expert discussions on the latest in silico prediction models, new approach methodologies (NAMs), physiologically based pharmacokinetics (PBPK), future methodologies, integrated approaches to testing and assessment (IATA) as well as methodology validation. Using a series of presentations from external experts and case study (plastic particles, polymers, tropane alkaloids, selective androgen receptor modulators) discussions, the workshop outlined and explored an approach that is fit for purpose applied to future human health risk assessment in the context of food safety. Furthermore, possible future research opportunities were explored to establish points of departure (PODs) using non-animal alternative models and to improve the use of exposure metrics in risk assessment.
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Houck, Marilyn, Uri Gerson, and Robert Luck. Two Predator Model Systems for the Biological Control of Diaspidid Scale Insects. United States Department of Agriculture, June 1994. http://dx.doi.org/10.32747/1994.7570554.bard.

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Hemisarcoptes (Acari: Hamisarcoptidae) is a parasite of scale insects (Diaspididae), tenacious pests of vascular plants. Hemisarcoptes also has a stenoxenic phoretic (dispersal) relationship with Chilocorus (Coleoptera: Coccinellidae). Chilocorus feeds on diaspidids, transports mites as they feed, and has been applied to the control of scales, with limited success. U.S.-Israeli cooperation focused on this mite-beetle interaction so that a two-component system could be applied to the control of scale insects effectively. Life history patterns of Hemisarcoptes were investigated in response to host plant type and physical parameters. Field and lab data indicated that mites attack all host stages of scales tested, but preferred adult females. Scale species and host plant species influenced the bionomics of Hemisarcoptes. Beetle diet also influenced survival of phoretic mites. Mites use a ventral sucker plate to extract material from Chilocorus, that is essential for development. Seven alkaloids were found in the hemolymph of Chilocorus and three were characterized. Examination of the subelytral surface of Chilocorus indicated that microsetae play a role in the number and distribution of mites a beetle transports. While Hemisarcoptes can be innoculatd into agroecosystems using various indigenous or imported Chilocorus species, the following are preferred: C. bipustulatus, C. cacti, C. distigma, C. fraternus, C. orbus, and C. tristis.
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Paterek, J. Robert. L51963 Environmental Benign Mitigation of Microbiologically Influenced Corrosion (MIC). Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), September 2002. http://dx.doi.org/10.55274/r0011299.

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The objective is to develop and evaluate environmental benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) on the internal surfaces of metallic natural gas pipelines. The goal is one or more products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this year has been to evaluate a number of methods to fractionate and concentrate the components found in the pepper extracts. The separation methods considered include size exclusion chromatography, hygroscopic and hydrophobic extraction with HPLC fractionation and analysis; preparative HPLC; and other methods based on the chemical class of compounds to be evaluated. The first classes to be studied are: terpenoids; phenolics; fatty metabolites; alkaloids; and other products of secondary metabolism in plants. Other methods to be reviewed as needed include: planar chromatography; supercritical water and CO2 extraction; and ion-exchange methods. A review of the patent literature and scientific databases found no evidence that any of the potential products have been patented, indicating potential for establishment of a strong intellectual property position. The work plan for the continuation of specific tasks of this project for two additional years was completed and accepted for funding. Laboratory testing protocols for control of biofilm formation and/or biocidal activities for both aerobic and anaerobic microorganisms known to support MIC were codified.
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Doncheva, Tsvetelina, Nadezhda Kostova, Vassil Vutov, Ina Aneva, and Stefan Philipov. Comparative Study of the Alkaloid Composition in Some Bulgarian Species of Genus Hypecoum. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, June 2019. http://dx.doi.org/10.7546/crabs.2019.06.04.

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